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The mornings are cool and the leaves are turning colors. Fall is here! And that means that it is the perfect time to plant garlic in your garden!
While garlic can be planted in the fall or the spring, I usually prefer to plant my garlic in the fall. This way it can develop a good strong root system over the winter. The garlic has a longer time to grow during cool weather which may lead to larger heads. Some people think that fall planted garlic also tastes better and has a more complex flavor.
A second reason why I usually plant my garlic in the fall is because I am usually planting garlic that I grew the previous season. By planting it in the fall so I will not have to store it as long, so the garlic is less likely to sprout early or have other issues during storage.
This post will explain the different types of garlic and how to plant it step-by-step. Let’s get started!
Related Post: Why Garden Planning Starts in September
This post may contain affiliate links, where I earn a small commission from qualifying purchases. I only provide links to products that I use personally and recommend highly.
When to Plant Garlic
Garlic should be planted in the late fall before the ground freezes for the winter. October through early November is the ideal time. It is best to err on the side of starting it too late rather than too early because too much top growth could make it more susceptible to winter injury.
What Type of Garlic to Plant
Make sure that you purchase garlic from a seed company rather than the grocery store. Grocery store garlic may be sprayed with chemicals to prevent sprouting, and it is not guaranteed to be free of disease.
There are two main types of garlic to choose from: hardnecks and softnecks. We will go through the differences below.
Hardneck garlic has one row of cloves around a stiff woody stem. The cloves are generally larger and there are generally 6-8 cloves per head. Some people think the flavor of hardneck garlic is superior to other types. However, hardneck garlic may not keep as well as softneck types and it is generally less hardy in warmer climates.
Popular hardneck varieties include: Music, German Extra Hardy, Purple Italian, German Red, Purple Glazer, and Chesnok Red.
This type of garlic has a few rows of cloves and does not have a central stem like the hardneck garlic. The cloves are generally smaller and there are around 10-20 cloves per head. Softneck garlic can be better in warmer climates and the heads keep for 9-12 months if stored properly.
Popular softneck varieties include: Inchelium Red, Italian Late, Silver White, and Blanco Piacenza.
What Type to Choose
What variety to plant is up to you! Personally I usually plant the hardneck types because the cloves are larger and easier to peel. But depending on where you live the softenecks or hardnecks may grow better. Try a few different varieties and see what you like!
Related Post: Garlic Review: Comparing Music, Duganski, and German Red
How to Plant Garlic
Step 1: Select a Site
Garlic grows best in full sun. Choose a site that has loose, well drained soil and few weeds.
After I choose where I’m going to plant my garlic, I like to mark my rows with heavy cotton string (affiliate link) tied to popsicle sticks. This helps me to see the edges of the row so I plant my garlic in the correct place.
Step 2: Prepare the Soil
Garlic are heavy feeders but too much fertilizer at this point can make the plants more susceptible to winter damage. You can add a small amount of compost or fertilizer at planting time but this is not required.
If you do add fertilizer, choose one that is higher in phosphorus such as bone meal so it will help the garlic to get a good root system established. It is best to wait to add too much nitrogen until after growth starts in the spring.
Step 3: Dig a Hole
Garlic needs to be planted 3-4 inches deep. How you dig a hole for your garlic depends on how much you have to plant. If you don’t have many cloves to plant you can just dig a small individual hole for each clove and drop it in. If you are planting your garlic in rows, you can dig a long narrow trench.
I am planting a lot of garlic this year (about 80 cloves!) so I like to plant it in a wide row about 18-24 inches wide. Instead of digging individual holes, I use a rake to move all the soil off to the sides of the row. This way I can plant the garlic all at once.
Step 4: Separate the Garlic into Cloves
Carefully separate the garlic heads into cloves right before planting. Each of these cloves will eventually grow into a whole head of garlic. Try to keep the skins intact because they will help protect the cloves.
If you have more garlic than you need, select only the biggest cloves to plant and save the smaller ones for cooking. Larger cloves produce larger plants. You cannot get a big garlic plant from a puny clove!
Step 5: Plant the Garlic
Plant the garlic cloves about 6 inches apart in all directions. Do not plant them closer than this because they will start to compete with each other for water and nutrients and not grow as big. Make sure the pointy ends of the cloves are facing upwards when you plant them.
When all the garlic cloves are placed cover them with soil. Gently pat the soil down with your hand and water the garlic lightly. Now wait for it to start growing!
Garlic shoots should emerge in a few weeks to a few months, depending on the temperature. Water lightly because garlic does not like heavy wet soils. The fall rains will likely keep it plenty wet, and too much moisture could cause the garlic to rot in the ground if there is poor drainage.
If you see green shoots appear you can add a few inches of mulch to help protect the plants against cold winter temperatures. Clean straw or leaves works well. You can pull the mulch away when the weather warms in the spring.
There you have it! Now that you know how to plant garlic you will be rewarded with beautiful garlic plants next spring that will be ready around July. Happy Gardening!
Don’t forget to pin for later!

domain: agronomy


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44 killed in United States due to storm
Due to storm Ida, at least 44 people have been wiped out in the United States. The storm badly hit the north-eastern states of the country.
According to media reports, ‘historic’ rainfall prompted an unprecedented flash flood in Louisiana, Pennsylvania, New York City and Mississippi.
Most of the New York’s subway system has been suspended after water flooded into stations, while people have been trapped in basement. A large number of vehicles swept away and lacs of people faced power outages due to storm.
For the first time, the US National Weather Service has issued flood emergency in New York. The authorities are trying to rehabilitate the transportation system. New York City Mayor Bill de Blasio said it was a historic weather event.
New York Governor Kathy Hochul asked people not to leave home and give the authorities some time to restore the train service.
According to NBC New York, one more person had died in New Jersey and seven had died in New York City, including a 2-year-old boy. Local American media reported that many people were stuck in their basements due to water surging through the metropolis.
New Jersey and New York’s governors have declared a state of emergency viewing the deteriorating situation of the ‘historic’ flooding.
PowerOutage.US, which gathers data from companies, claimed that over 0.2 million houses were deprived of electricity in five states which received most of the rains. Pennsylvania, New Jersey, New York, Connecticut and Massachusetts were the states which experienced power outages.
Meanwhile, the Meteorological Department had on September 1 predicted that rains would take place in Karachi for three days starting from Wednesday.
On September 1, rains had happened in different parts of the country including Sindh and Balochistan. Several areas of Karachi had also received light rain. During the day, temperature remained dry and hot in the megalopolis.

domain: news


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Blog: UN warns poor maize harvest likely
Katy Askew | 30 April 2015
The United Nations Food and Agriculture Organisation (FAO) has warned that lower maize harvests in Africa could "trigger food price increases" in the region.
According to the agency, 2015 maize production is expected to fall by about 15% in the subregion. Declines are lead by South Africa, where production is expected to fall by 26%. Malawi, Zambia, Botswana, Lesotho, Madagascar, Mozambique, Namibia, Swaziland and Zimbabwe are all expected to see lower harvests compared to a "bumper" harvest last year.
"Last year, the subregion saw a bumper harvest, which has made this year's harvest prospects look even weaker so we have to be cautious until governments, often with the support of the FAO, have completed all the assessments in the coming days," said David Phiri, the FAO's subregional co-ordinator for southern Africa. "The carry-over stocks from 2014's bumper maize crop is expected to partly offset the impact of lower domestic production and somewhat contribute to stabilising national supplies in some countries."
The fall is mostly due to the impact of erratic weather conditions, the FAO suggested. These have included the late start of seasonal rains in November, followed by heavy rains that caused flooding, and then a long dry spell in the southern areas.
The poor outlook is already having some impact on cereal markets. South Africa recorded significant price increases in February – although the rise eased in March following improved rains.
The BBC turned to just-food today for insight on the price dispute between Tesco and Unilever....
Just weeks after buying UK turkey processor Bernard Matthews from administration, food tycoon Ranjit Boparan has struck a similar deal....
Shares in Tyson Foods slumped on Friday, closing down almost 9% after an analyst claimed a lawsuit facing the company could hit the US meat titan....
- Price an underlying tension across European FMCG
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- Constellation Brands, Inc. (STZ) - Financial and Strategic SWOT Analysis Review

domain: food


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How to improve lifestyle vision in patients with severe corneal irregularities: Small-Aperture Intraocular Lens (IC-8) implantation
First Author: L.Vicchio ITALY
Co Author(s): M. Branchetti F. Franco
The purpose is to consider the impact of small-aperture intraocular lens (IC-8) implantation in eyes with cataract and corneal irregularities. The aim of the surgery is to reduce high order aberrations and to improve quality and quantity of the central visual acuity.
University Hospital of Careggi, Florence, Italy
Eyes with severe corneal irregularities (due to keratoconus, postradial keratotomy, scarring after trauma, previous penetrating keratoplasty) were enrolled. Each patient reported a poor quality vision due to aberrations. We excluded eyes with important diseases that could influence the results (as glaucoma, maculopathy, progressive keratoconus). Conventional phacoemulsification with implantation of IC-8 was performed. The primary endpoint was the best corrected visual acuity (BCVA), visual function questionnaire and the visual field.
Six eyes of four patients (two bilateral implantation) were enrolled. For each patient, BCVA, vision and lifestyle quality were evaluated. In all patient, we registered an improvement in all parameters.
Pinhole IC-8 Lens implant is a safe and useful method to reduce the effect of high order aberrations in irregular cornea.

domain: literature


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I was working my way through Sly 3.
Nope. I haven't played that game. But i suggest you to check out walkthrough videos on your YouTube. There are many videos of this game actually. My recommendation is a channel named “RadBrad” on Youtube. He is an awesome guy with fun to watch videos.
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domain: entertainment


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Artwork, framing, decorative mirrors, and interior decor for all your interior design needs. Steffanino's has been a leader in the visual arts and design trade for over twenty years. We are located in Costa Mesa in Southern California and provide wholesale fine artwork, commissioned art, decorative mirrors, custom framing, and many other interior decor to the trade and hospitality industry. Our art gallery showcases our in-house commissioned art and framing capabilities and we offer a wide range of services including printing and art consulting. Take a look inside for a brief tour of our gallery and see how we can enrich your environment with art.
Design and Supply is an award-winning Philadelphia area interior design and purchasing company. Design and Supply's diverse creative team specializes in interior design for boutique to luxury hotels, restaurants, ski resorts, senior living, healthcare and more. What we do and how we work is... Read More
- Visit us online and you’ll find our complete catalog at your fingertips, including metal frames, lit mirrors, and more. - Custom engineering AND timeless standards: all DOMESTIC fabrication, made in our factory in Los Angeles, CA. - Technology-focused, design savvy, and ready to build your...
RFA Decor has been providing art and mirrors to wholesale and retail clients since 1979, but what sets us apart is our full range of related service offerings from initial art consulting to final installation. We are a single source for all art-related needs. We offer art at every price...
Full time, highly experienced art consultanting professionals offer personalized service to every client. They provide a relaxed atmosphere for the client while contributing their expert knowledge and advice. They will assist the customer in choosing the latest styles and most appropriate... Read more
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Steffanino's has everything you need to complete any design project. From the large selction of poster art and fine art to our in-house framing and commissioned artists, you are sure to find what you are looking for. Steffanino's also provides limited art reproduction and photo enlargement... Read more

domain: artistic


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Ultra FCC ADDITIVES™
G.W. Aru, LLC is pleased to offer a full line of Ultra FCC Additives™ manufactured by our OEM partners and suppliers in the USA, China and Europe. These additives can be packaged in any manner to meet your requirements and we can work with our logistics partners and suppliers to further optimize the material handling requirements and costs for your additive usage needs. Independent Quality Control and Assurance is provided by Cat Testing Labs, Inc (CTL), which is trusted by many refiners to provide QC and QA of catalysts and additives produced by US-based and overseas manufacturers.
Great FCC Promoter™ (GFP™)
We are pleased to offer a new and innovative, patent pending CO oxidation promoter for the FCC process. Great FCC Promoter™ (GFP™) brings value to our refining customers by providing excellent CO promotion at significantly reduced Platinum Group Metals (PGM) content compared with the industry standard platinum and palladium promoters widely used today.
Platinum-based FCC promoters were developed in the 1970’s when platinum prices were ~$100/troy ounce. Palladium-based promoters to meet the EPA’s FCC NOx reduction requirements were developed in the early 2000’s when palladium prices were ~$200/troy ounce. Since then, these PGMs have increased in cost by 5 to 10 times. The substantially increased costs of the PGMs have simply been passed on to the refiners as R&D investment for new CO promoter technology has been lacking from the major suppliers.
Our proprietary and patent pending composition of matter and manufacturing process enables us to significantly reduce PGM content while maintaining CO oxidation performance, this for both platinum (GFP™-Pt) and palladium (GFP™-Pd) promoters. This provides significant savings for the refiners; e.g. at $1,000/troy oz, a 1,000 ppm promoter has $14.58 PGM per lb promoter. Further, because of the NOx formation chemistry from PGMs in the FCC process, GFP™ has promise to reduce NOx emissions compared with both the platinum and palladium promoters in use today.
We have developed GFP™ with testing support from CPERI and their world-renowned personnel and facilities in Thessaloniki, Greece. GFP™ is custom manufactured in the European Union by our manufacturing partner, Euro Support, at their best in class ISO and Responsible Care Certified factory. We are developing additional patent-pending technology, Super Low NOx™ (SLN™), to provide even lower NOx emissions from CO promoter usage.
CO promoters in platinum and non-platinum variants
CO promoters for Super Low NOx (SLN™) emissions

domain: chemistry


Rep. Steube Says US Shouldn’t Have Raised Debt Ceiling With Spending Spiraling Out Of Control
Rep. Greg Steube recently made an appearance on Newsmax where he said that while our country’s spending is raging out of control, the debt limit should not have been raised, especially while Democrats are doing their darnedest to get a massive “socialist welfare program” passed into law that will tack another $5.5 trillion to the problem.
“This is my second term,” the Republican congressman stated Wednesday on ”National Report.” “When I got elected, the deficit was $21 trillion. It’s almost $30 trillion as we sit here today. Just in the last 18 months, our Congress has spent $11 trillion, and just to put that into perspective, we only take in $3.5 trillion a year.”
The House on Tuesday night approved legislation that will allow the current national debt limit to rise to about $28.8 trillion, or by $480 billion. The current national debt is at $28.4 trillion. President Joe Biden is expected to sign the bill, particularly after Treasury Secretary Janet Yellen’s warnings of severe economic problems by Oct. 18.
“Washington has a spending problem,” Steube went on to state. “Why in the world will we raise the debt ceiling to pay for a socialist welfare program? We should be reining in the spending and cutting spending in Washington, not increasing it.”
Steube also criticized House Speaker Nancy Pelosi D-Calif., after her comments to the media that she thinks they could do a “better job of selling” the $3.5 trillion spending bill to the public.
“I mean, for the most part, the left-wing mainstream media is trying to cover for the Democrats,” Steube continued. “But this bill is so bad that even Democrats are starting to push back. … People are starting to push back once they’re starting to find out what’s actually in this $3.5 trillion spending bill.”
Steube also said during the interview that he doesn’t know what difference it makes to push the debt ceiling to December, “as Democrats have been talking about the infrastructure plan since February, and the measure is still being blocked by progressives who won’t vote for it unless it includes the $3.5 trillion spending bill,” the report added.
“If they would have just passed the infrastructure plan that passed the Senate. I believe that would have passed the House,” Steube went on to add. “I wouldn’t have supported it, but it would have had enough votes to pass the House.”


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Pie and pasty manufacturer Peter’s Food Service has unveiled a new logo design as it continues a plan to turnaround its business.
The new design has been rolled out across all of the company’s retail packaging ready for supermarket St David’s Day promotions.
Mike Grimwood, Managing Director of Peter’s, said: “We hope this new style and messaging really resonates with our customers, particularly as families are spending more mealtimes together at home.”
Peter’s makes a £2.8m loss
The firm, based on Bedwas House Industrial Estate, has endured difficult trading recently – making a loss in three consecutive years.
The company’s latest annual accounts lodged at Companies House show Peter’s made an operating loss of £2.8 million on revenue of £59.3m for the 12 months ending June 1, 2019.
This was an improvement on the previous year’s £3.6m loss – although the firm is in the process of turning its business around.
The directors report accompanying the accounts states: “The company’s overall profitability has improved during the period, following a restructuring of the business’ overhead base and a conscious move away from less profitable products and customers.”
It continues: “Since the balance sheet date, the company has concluded several financial transactions that have generated significant cash funds for the business, including the sale and leaseback of the company’s plant and machinery.
“In addition, the company has also gained new business with several key customers that has improved both sales and profitability for the current period.”
As part of its turnaround plan the company sold the freehold of its premises for £5m in June 2018 and launched a new range of low-fat products under a new brand called Nurish.
While the company accounts do not cover the time of the coronavirus pandemic, the directors’ report does make mention of it.
It notes that further trading restrictions imposed by the Welsh Government may require the company to seek funds from external sources to make up any shortfall in working capital. The company said it believes it would be able to secure that funding if needed.
In October last year the company had around 48 staff members test positive for coronavirus after more than 600 staff were tested over two days.
- Investigation into possible plastic contamination underway at quarry
- Is part of Ystrad Mynach moving to Llanbradach? Is Ynysddu merging with Crosskeys?
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Established by family man and entrepreneur Stan Thomas as a small pie manufacturer in Merthyr Tydfil, “Thomas’ Pies” supplied highly sought-after savoury pastries to the Valleys.
The Thomas family, including sons Sir Stanley Thomas OBE and Peter Thomas CBE, moved the business to its existing home in Bedwas, Caerphilly in 1970 and created the now highly successful Peter’s brand.
Although Peter’s is no longer run by the Thomas’, the founding family maintains a close affinity with the business and recently called to celebrate the fiftieth anniversary. Prior to his passing in 2015, Sir Stanley enjoyed visiting the Bedwas bakery and meeting with staff.
Mr Grimwood said: “Peter’s is Stan’s, Stanley’s and Peter’s legacy – a household name that supplies retailers and venues across Britain, and based in a modern, purpose-built factory in Bedwas.
“They had a passion for pastry, innovative ideas and a brain for business. Stan saw the opportunities the end of meat rationing offered in the 1950s and created a company which simply grew and grew, today employing 700 staff and selling millions of pies every year.”
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domain: finance


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Georgia Mother Charged With Felony After Starving Her Newborn Baby [Photo]
These child abuse incidents are so disturbing, just the thought of what an innocent child went through is beyond horrifying!! NY Daily News reports; “Jamie Lynn Bentley, a 33-year-old mother of eight from Georgia has been arrested and charged with starving her newborn baby until he was nothing but skin and bones.
A Georgia mother of eight is charged with felony cruelty to children after she allegedly starved her six-week-old baby to the point that it lost 2 lbs. after birth. Jamie Lynn Bentley’s newborn son couldn’t be recognized as a baby after it was allegedly fed just two ounces of food every six hours in the first weeks after birth, according to a Douglas County attorney. By the time authorities discovered the newborn’s withering condition in Lithia Springs they say it was eating its own muscle mass to survive.
“It was skin and bones,” Kristi Wilson, with the Douglas County District Attorney’s Office, told the Douglas County Sentinel. “They couldn’t even recognize it was a baby in the pictures.” Wilson said the 33-year-old mom has faced allegations of drug use for some time and has had her other children removed from her custody before.
She said it was Bentley’s ability to pass a drug screen for meth that allowed her to leave the hospital after her baby’s delivery. But just six weeks after a Douglas Family and Children Services nurse visited Bentley’s home and weighed the baby, the child was rushed back to the hospital.
Bentley was initially allowed to stay at the hospital with her baby in an effort to help feed him, which allegedly didn’t last long.
“When they’d come and wake her up to feed the baby she told them she wasn’t feeding that baby every two hours, that drove her crazy and they need to get the (expletive) out of her room,” Wilson told the paper. “And so she was excused from the hospital, so they took other precautions to feed the baby.”
Bentley has reportedly argued claims that she wasn’t feeding her youngest son.
She allegedly told authorities that she had purchased $25 worth of baby formula and that half of it had been fed to her youngest. She also insisted that she was able to pass a drug test.
Hospital workers have argued that claim, saying it would be impossible for the baby to lose so much weight so fast.
Two weeks after the infant’s hospitalization they said it had returned to its original birth weight.
“The state is adamant that her bond should be denied. Certainly we feel she is a risk of reoffending,” said Wilson.
Douglas County Magistrate Court Judge Susan Camp shared in that decision on Friday.
“It looks like you really didn’t care anything about the baby and you were just doing what you wanted to do,” she told Bentley just before denying her bond. “You may have to take this thing to trial because it looks really bad.”
Bentley’s seven other children were removed from her custody as well, the Sentinel reports.”
Source: NY Daily News

domain: sociology


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Attorney Douglas Brannon. JIM WITMER / STAFF
Attorney Douglas Brannon. JIM WITMER / STAFF
Brannon is one of several attorneys representing Guglielmo, a veteran who was taken to the jail after a disturbance at a area homeless shelter in January 2015. Guglielmo says he was beaten by corrections officers before he was taken to the hospital with head injuries that left him wheelchair-bound. The county claims Guglielmo had head injuries from fighting at the shelter before getting to the jail.
RELATED: County blames health care provider for jail inmate's injuriesIn an effort to prove "the pattern and practice of excessive use of force at the Montgomery County Jail," Brannon submitted as evidence in the case a video of former inmate Amber Swink being pepper-sprayed while unable to move in a restraint chair.
Swink settled her lawsuit in April 2017 for $375,000. The sergeant who pepper-sprayed her, Judith Sealey, pleaded guilty to disorderly conduct and surrendered her law enforcement certification last month.
But questions remain about how the pepper-spray video disappeared from county records. It only became public when Brannon, who represented Swink, posted a copy of it on his website.
County officials say the video was stolen from the county by former Sgt. Eric Banks. Banks' role in how the pepper-spray incident became public has emerged in his court testimony in the Guglielmo suit and interviews with the Dayton Daily News. Banks told the Daily News that he gave a copy of the video to attorneys and also told the FBI about it because he feared the county would try to cover up the pepper-spray incident.
“Banks testified under oath that he allegedly engaged in a conspiracy with former employee Ransley Creech and Attorney Doug Brannon in the year 2016 to steal Montgomery County Sheriff Office property,” says a March 15 filing by county prosecutors. Prosecutors said in the filing that they wanted to depose Brannon and Creech, another former sergeant.
RELATED: Former jail sergeant alleges cover-up of pepper-spray incident"The Court should note that Defendants are not stating that anyone engaged in criminal conduct as Defendants have no firsthand knowledge of their actions," says the county's filing, which was unsealed Friday. "Rather, Defendants are citing the Court to the sworn testimony of Eric Banks given earlier this month in which he states facts that could be construed to constitute a crime."
Ovington wrote that the county provided a “gross mischaracterization” of Banks’ testimony, in which he clearly said that what he did “was absolutely legal.” The judge also noted that no one has been charged with such a crime.
The original video and other records of the incident disappeared after they were sent to the major in charge of the jail, according to an internal affairs report obtained by the Daily News.
RELATED: No cover-up of pepper-spray incident, sheriff's investigation findsIn court filings, Brannon calls the county's claims "clearly an attempt to intimidate counsel from pursuing this case as well as the other cases in which Douglas Brannon is pursuing against the Montgomery County Sheriff's department on behalf of his clients."
Brannon said the county also filed a complaint against him with the Ohio Bar Association.
Ovington’s ruling prevents the county from deposing Brannon.
“Defendants’ attempt to depose Mr. Brannon appears to be nothing more than a fishing expedition,” she wrote. “Defendants’ implication that he regularly assists his clients in committing crimes lacks any support in the record, insults Mr. Brannon, and reflects poorly on the professionalism of the Montgomery County Prosecutor’s Office and (its hired) attorneys.”
The judge ordered the county to repay Brannon for fees and expenses related to their attempts to depose him.
Contacted for comment Monday, Brannon said: “It’s unfortunate that the county and the county defendants have engaged in this continuous course of conduct.”
Prosecutor’s office spokesman Greg Flannagan released a statement Monday saying the court filings seeking to take a deposition of Brannon was signed and filed by the insurance company’s attorney, and not prosecutor’s office attorneys. He said the county has not filed any ethics complaints against Brannon.
Flanngan said the Montgomery County Prosecutor’s office is considering filing an objection to the judge’s ruling, saying the office was “very disappointed by the decision and order, and the tone of the decision and order, as written by Magistrate Ovington.”


President Joe Biden’s Federal Trade Commission (FTC) Chair has come under fire from an interim report revealing “a serious attack on the Constitution,” ahead of the much anticipated meeting in the House regarding the weaponization of the federal government.
The House Judiciary Committee’s Select Subcommittee on the Weaponization of the Federal Government was last convened a month ago and the Chair Rep. Jim Jordan (R-Ohio) released an interim report claiming the FTC Chair, Lina Khan, directed the agency to orchestrate “an aggressive campaign to harass Twitter,” and thus undermining our freedom of speech.
Since Elon Musk bought Twitter in October, the FTC has vigorously pursued them via numerous demanding letters seeking to look through internal communications of the company and over 300 more requests were submitted to the company in what seems like unending harassment.
The report released by Jordan said, “The FTC has demanded that Twitter provide, among other things… Information relating to journalists’ work protected by the First Amendment, including their work to expose abuses by Big Tech and the federal government.”
In a reaction to the report which said the FTC must “identify all journalists”, billionaire Dr. Jay Bhattacharya posted to Twitter, “The Biden administration’s casual violation of the First Amendment should shock every journalist, even those not fond of @elonmusk. This is a serious attack on the Constitution by a federal agency.”
Elon Musk has been claiming this for years and responded to the report on Twitter writing, “A shameful case of weaponization of a government agency for political purposes and suppression of the truth!”


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World famous record label Anjunabeats brings their annual label pool party to The Raleigh in Miami on Sunday, March 20, 2016.
Closing this year’s Miami Music Week—and it usually does—Above & Beyond’s Anjunabeats label is hosting its very own must-see event at The Raleigh Hotel in South Beach.
With the Anjunabeats North American Tour underway, the Miami stop boasts one of the tour’s biggest lineup’s to date. With electronic dance music forces Andrew Bayer, Audien, Genix, Grum, ilan Bluestone, Jason Ross, Jerome Isma-Ae, Kyau & Albert, Maor Levi, and Nick Sember included on the talent roster, Anjunabeats in Miami is one of the week’s most promising events.
Anjunabeats in Miami, which just recently celebrated its 15th year anniversary in Miami, is certain to provide stellar entertainment, likeminded Anjuna enthusiasts, and fun in the sun from noon until 10PM.
Watch Anjunabeats in Miami 2015 official after movie:
Tickets for Anjunabeats in Miami 2016 are available HERE.
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It’s the last day of the decade, so what better way to close out 2019 than with our picks for...


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James McAvoy and Anne-Marie Duff became a couple in and married in Almost 10 years later the two announce their divorce. They’ve kept things very friendly for the sake of their son and continued respect for each other.
James McAvoy isn't one to go into grave detail about his personal life. He's an actor, not a tabloid obsession, and he'll keep it that way, thank you very much. Anne-Marie Duff. The year.
James McAvoy Opens Up About His Divorce from Anne-Marie Duff: 'My Life Has Changed Massively' Entertainment Press/Splash News Online "My life has changed massively," the .
JAMES McAvoy is a Scottish actor best known for his roles in X-Men, The Last King of Scotland and Atonement. But what else do we know about the actor, when was he married to Anne-Marie Duff and. James McAvoy and Anne-Marie Duff are filing for divorce. The couple - who met on the set of TV comedy Shameless - have announced they are parting ways after nine years of marriage, revealing the.
FILE - In this Oct. 7, file photo, actors Anne-Marie Duff and James McAvoy pose for photographers upon arrival at the premiere of the film "Suffragette," at the opening gala of the London film festival in London.
Mar 28, · Matthew Perry Takes The Friends Apartment Quiz - The Graham Norton Show - Duration: The Graham Norton Show 6,, views. Actors James McAvoy and Anne-Marie Duff met on the British TV show mrrak.info was in And despite their age difference – Anne-Marie is older by nine years – .

domain: celebrity


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Is this the week to watch a movie in which a predatory man and his patriarchy-upholding wife get hacked to death with a hatchet? Maybe! Chloë Sevigny spends most of Lizzie as if she’s trying not to throw up, and really who can blame her. The unmarried daughter of a creepy banker and a loveless stepmother, 32-year old Lizzie Borden is too old to be a debutante and too young to be a spinster. What’s a girl to do? The screenplay is odd and a little too long, but Sevigny is perfect, her droopy eyes and pale skin suggesting a woman exhausted with life – she’s seen too much – or maybe just a need to get out of Fall River once in a while.
Lizzie screens this week at Showcase Cinemas Warwick and the Picture Show at South Coast Marketplace in Fall River


One, they never intended to work here but didn't want to waste an excuse to fire up the virtue signal.
Two, they're a grumpy Californian who's been looking for an excuse to say we're not a worthy state to practice the hallowed art of filmmaking since 2008 or so.
I still hold by that.
But I ran into a blog post that points out an interesting idea. Namely, that boycotts are effective locally, but rarely nationally and never internationally.
Which makes sense. I've seen a couple of eateries go down for good because enough people got cranky with them. But the only national boycott I can think of that was effective in the long term was Dick's after they destroyed their stock of AR's because reasons. Haven't looked at them lately but that move hurt them for at least a few quarters.
Internationally, on the other hand, the US may no longer a market that can do significant damage by its removal.
There are more moviegoers in China than there are people in America. India's not too far behind.
There are more NBA fans in China than there are Americans total. MLB is chasing that market segment too. NFL lags behind because American Football is culturally niche.
Cola drinkers, same deal.
And if any of these international companies annoy a segment of Americans, who cares?
Well, as Stacey pointed out, the people working for the internationals you're trying to boycott. A lot of whom probably agree with you, but don't have the luxury of dropping their meal ticket at the moment.


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Ryan “Fluff” Bruce is a guitarist in Dragged Under and a YouTuber who reviews gear on his channel Riffs, Beards, and Gear.
On this episode, Fluff, Eyal Levi, and John Browne dive into:
Why guitarists should learn video basics
Dealing with gear elitists
Handling imposter syndrome
Follow Riffs, Beards, and Gear on YouTube.
Follow Fluff on Instagram and Twitter.
Want to level up your guitar game? Check out Riffhard.
When you sign up, you'll get access to:
Over 100 video tutorials with tabs
A chance to enter our monthly King Of The Riff contest
Livestream Q&As and other events
Our private community
Be sure to follow Riffhard on Instagram and Facebook.
Follow Eyal Levi on Instagram.
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Like this show? Please leave us a 5-star review - even one sentence helps!
Learn more about your ad choices. Visit megaphone.fm/adchoices


text: David Lee Pancake’s sculptures and illustrations represent a varied and unique repertoire of his personal interests. He pursues a wide variety of subject matter that includes dragons, superheroes, D&D Characters, abstracts and horror sculptures and paintings. His talent expresses equally in clay or canvas. David loves to play with textures in his sculptures and his attention to detail is revealed in his careful application of dragon scales and feathers. He states: “I love detail and texture and angels, dragons, and other mythical creatures allow me the freedom to play with the clay and bring to life what’s inside my head.” The fantasy creations of David Lee Pancake are gracing homes and businesses all over the world and we are sure you won’t forget his name, just think about your favorite breakfast food.

domain: design


Joran Van der Sloot: Fact vs. Fiction and False Reports
Joran Van der Sloot will appear before a judge today in Lima. (Court's press release here, Spanish version here.) The hearing will be at Miguel Castro Castro prison. Again, the media reports are all over the place as to what charges the prosecutor has asked the Judge to consider and who his lawyer will be.
First off, contrary to some news reports Sunday (which appear to be based on this one from Lima, translation here), New York attorney Joe Tacopina is not going to Peru (at least not at this time) but he has been consulting with Joran's mother and assisting her in securing a top attorney in Peru. How do I know? He's a good friend of mine and he just told me.
Second, as I understand them, the charges being contemplated are murder (with special circumstances) and simple theft (not aggravated robbery.) The best source is the Court's press release announcing the charges on June 11, 2010. Translation, followed by Spanish: [More...]
|< Peru's Media Displays of Prisoners : This is How We Do It | Supreme Court Upholds Material Support of Terrorism Law >|


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CLIA is partnering with Cruise Weekly to invite you to nominate in CLIA’s 21st annual Cruise Industry Awards.
CLIA’s 21st annual Cruise Industry Awards are a chance for dedicated travel agents to gain the recognition they deserve.
Nominations are now open, allowing CLIA members to put themselves forward or nominate a colleague for the cruise industry’s biggest accolades.
Each award helps recognise the critical role Australian and New Zealand travel agents have played in cruising’s comeback. They bring recognition for travel agencies as well as valuable industry standing for individuals.
Importantly, the awards honour more than just sales – there are categories for Rising Stars, creative Cruise Promotions, and Champions of the Cruise Industry. Any CLIA member is a potential candidate.
Nominations close 30 November 2023. For more information, visit CLIA Cruise Industry Awards.

domain: travel


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We collaborate with some truly extraordinary people here at the Foxfeet Collective, and for us, there is nothing more exciting than to be able to inspire and communicate with people through fashion. So we’ve teamed up with some amazing Perth creatives to bring you the Editorial Series; photo shoots organised and styled by our very own fashion team.
Creative Director and Stylist: Alexsia Sargent
Makeup: Dana Sekar
Models: Lauren Garnett, Mia Clark and Georgia Hondris (La Mods Modelling Agency)
Photographer: Michelle Maretha (Lepak Media)
For more information on the Foxfeet Collective or opportunities to collaborate contact us at email@example.com or come in and visit us at 241 Hay Street, Subiaco WA 6008.


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Having a false dollar, presumes a risk. It may seem mischievous, that just as they gave it to you, you will also put it back. But it turns out that by chance of life you can go to jail if you are caught in the process.
The dollar is an international currency and the origin can come from any country that allows transactions. Therefore, if you dare to receive the money without being familiar with the ticket, it is better that you go to someone close to you if you know it, before you pass for unsuspecting and lose your money, for accepting fake bills.
However, with a little more time, you can analyze the characteristics that real notes should have, to avoid any ticket that you think is doubtful. In the networks there is plenty of information on how to detect a fake banknote. The important thing is that you think, what you should do as a good citizen if a false bill has reached your hands.
There are many unfortunate cases of people, who because they feel powerless in the face of theft, decide not to stay with them and have got into serious problems. If the amount is very large, the risk of returning them to the system is greater, if more than one person identifies as a fraudster you have your days off counted.
Like the woman who was the victim of a scam, she returned the action and distributed the fake dollars in several transactions, she reported to the police and was booked as a scammer. The real thieves are free of guilt and the woman is prey and frustrated, for lack of good sense.
The legal sanctions may vary depending on the country, but on average a penalty of three to fifteen years of imprisonment is established for those who falsify or put into circulation the coins or counterfeit bills. Whoever has received the fake banknote or coin in ignorance of its authenticity and equally places it in circulation once it has been found out, will have to pay fines imposed.
It is totally impotent to receive false money, it deserves that if you have doubts that it is doubtful, you must inform the authorities. If the currency is foreign like the case of dollars and you are not in the United States, banks should collaborate in checking their authenticity.
Demonstration that you have been scammed
If they are authentic, they can return the equivalent of the amount if it is a local currency, if they are foreign they will return the delivered ticket. In addition to a report verifying the authenticity of the financial institution.
If the ticket is false, unfortunately the bank will keep the ticket and your money will be lost, from the moment you accepted the ticket to the scammers. It is worth placing the complaint and giving all the possible data to capture them.
Clear signs that it is a fake bill
There are more fake bills circulating than you think about it, it is necessary to keep your eyes open when receiving money in cash, even from ATMs, but if it is not the currency with which you normally move. It details the texture, the painting and the security tapes, almost all the bills of the world have them and strongly rejects if you doubt.

domain: law


Granite crushing machine price in ghana,600 tph granite crushing plant in ghana production line configuration: jaw crusher, HP multi-cylinder hydraulic cone crusher, single-cylinder hydraulic cone crusher, vibrating screen, vibrating feeder, etc. jaw crusher. hydraulic cone crusher. vibrating screen. vibrating feeder. main equipment in 600 tph granite crusher plant for sale in ghana
Jaw crusher is widely used in crushing the medium particle size materials of varieties of minerals and large materials, and it is widely used in mining, smelting, building material, highway, railway, water conservancy and chemical industry and other industries.
Impact crushers are also known as impact breakers or impact crushing machines. It can crusher the material whose side length is below 100-500mm and highest compressive strength can reach to 350Mpa.
Cone crushers are also known as cone breakers. Compressive strength of cone crusher is no more than 250MPa. Cone crusher is widely used in mining, metallurgy, building materials, chemicals and other sectors to crush hard and medium hard materials.
Sand maker is also known as impact crusher or sand making machine. It is a kind of equipment with high technology.
Sand washer is also called sand washing machine. It is the necessary equipment for washing sand making.
Ball mill is suitable for grinding various ores and other materials. It is widely used in mineral processing, building materials and chemical industry.
The wheel-mounted mobile impact crusher as a kind of mobile impact crushing plant adopts the star product of our company: the impact crusher. As a leading rubber-tyred mobile impact plant
Charcoal briquette machine is also known as charcoal briquetting machine, charcoal ball press machine, or charcoal pressure ball machine.
Rotary screen is mainly used for sieving big or small stones, separating soil and gravel, coal blocks and coal powder, etc. It can also be called gravel screen or stone separator. Since roller device is composed of filter screen, it is also called rotary sieve.
Hammer crusher is composed of chassis body, rotor, hammer, back liner, sieve, etc.. It is suitable for conduct coarse, medium, fine crushing for materials with the compressive strength less than 180MPa like limestone, coal, gypsum, shale and other types of brittle materials.
Roll crusher (roller crusher) is suitable for the fine crushing of the materials with feeding size less than 110mm, and finished particle size 3-30mm.
Compound crusher is also known as combination rock crusher. Compound crusher is mainly used for medium or small cement or clinker crushing.
Actively listen to customer needs, carefully build product quality, and sincerely provide satisfactory services
7*24 hours waiting for you to answer your questions at any time
Professional tailor-made, comprehensively solve the needs of users
Provide technical training to ensure that you have knowledge of equipment operation
Perfect after-sales service system, let your production sit back and relax
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Getting My 90 essential vitamins and minerals To WorkAlso, you may eat dairy solutions including milk and yoghurts, along with non-vegetarian goods like fish. Entire wheat bread made up of bran and germ has twice the magnesium articles when compared with white bread. Water also incorporates a significant magnesium articles; difficult water has much more magnesium than soft water, Even though difficult water is just not superior for your body, especially the kidneys.
Disclaimer: Each exertion has been produced in order that the data supplied by Cerner Multum, Inc. ('Multum') is accurate, up-to-day, and finish, but no promise is produced to that influence. Drug facts contained herein can be time delicate. Multum data continues to be compiled to be used by healthcare practitioners and buyers in The us and so Multum will not warrant that uses outside of the United States are proper, Except specially indicated or else. Multum's drug data would not endorse prescription drugs, diagnose individuals or recommend therapy. Multum's drug information is surely an informational resource created to aid accredited healthcare practitioners in caring for their people and/or to serve customers viewing this provider for a supplement to, instead of a substitute for, the skills, ability, awareness and judgment of healthcare practitioners.
It is essential for over 300 unique chemical reactions in the body, like retaining your Strength degree, supporting you relax, and sustaining the health of the coronary heart and blood vessels. Sadly, in many of the designed world, magnesium deficiency might be the commonest nutritional deficiency.
Enter The form, shade, or imprint within your prescription or OTC drug. Our pill identification Resource will Show pictures you can Assess to the pill.
Stopping bleeding problems in newborns with very low amounts of vitamin K (hemorrhagic disorder). Offering vitamin K1 by mouth or being an injection to the muscles can protect against bleeding difficulties in newborns.
Continue having magnesium gluconate and talk with your health practitioner For those who have any of such less Get the facts serious Unwanted effects:
Approximately fifty% of our entire body’s complete magnesium is saved within our bones, when the remaining section is predominantly located in the cells of physique tissues and organs. Just one% of it is on the market in blood, although the human entire body is superb at regulating a relentless amount of magnesium during the blood.
We place celebs on the exam to see which issues they prefer over Some others. Pet dogs or cats? Cake or kale? You will have to look at to...
Even if you previously try to eat a healthy diet plan, having prenatal vitamins is essential to ensure that you get all the nutrients you and yo...
Discuss with health industry experts and other people like you in WebMD's Communities. It is a safe Discussion board where you may develop or get involved in guidance teams and conversations about health matters that fascination you.
Cures migraines – Migraine assaults terribly have an impact on lots of Individuals, Specifically, ladies. Magnesium supplements and liquids noticeably decrease the severity of such assaults and may also assist in lowering the speed of recurrence.
The health benefits of pink rooibos tea are considerable. This type of tea has customarily been well-known due to its ...
By no means delay or disregard searching for Expert clinical information from the physician or other qualified health treatment service provider on account of something you've got Keep reading WebMD. You need to normally speak with your health practitioner or health treatment Skilled before you start, quit, or alter any prescribed part of your respective health care approach or cure and to determine what course of therapy is good for you.
Pleasing picky eaters When your child's a picky eater, each and every meal can appear to be a battle. Learn how to acquire the food wars!

domain: medical


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Beginning an Instructional DVD on Creating Armatures for Sculpting
I get countless requests for where to buy ready made human armatures. Well the one source I had has dried up. So I've decided to show how to make wire armatures for creating clays.
This will be a new Instructional DVD on which I'll include making and plotting out armatures for human, and some animal armatures.


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Moody Much? The Effects of Sleep on Our Moods
By Lissa Coffey
Ever have one of those days? You know the ones – when you are out of sorts and easily irritated, when nothing seems to be working and everything takes more effort? We’ve all been there. And though we tend to blame the traffic, or our co-workers, or the weather, chances are the real culprit that we haven’t gotten enough sleep.
Sleep research shows that there is a definite correlation between being sleep deprived, and feeling angry, hostile, and irritable. In addition, a chronic lack of sleep is associated with depression and anxiety.
When it comes to emotions, sleep deprivation seems to be the cause of increased emotional reactivity. People who experience sleep loss are much more likely to have a negative reaction when things don’t go well for them. Why is this? It’s got to do with the brain and the part of the brain known as the amygdala. The amygdala is responsible for processing negative emotion. When we don’t get enough sleep there’s a disconnect between the amygdala and the area in the brain that regulates its functions. So, sleep loss affects us in two ways: we are more likely to experience negative emotions (or worse than usual negative moods), and we also have less of an ability to regulate those moods.
A lack of sleep also affects our positive moods – making them less positive. Without adequate sleep we feel less happy, less friendly, and less compassionate. Even when something great happens for us, for example we win an award, we don’t experience it as positively as we would have if we had gotten enough sleep. Even losing just one hour of sleep could cause us to feel nervous, hopeless, or restless.
The good news is that a good night’s sleep can restore these brain connections so that the next day we can do better, and be better, both socially and emotionally. And of course, it follows that adequate, quality sleep promotes positive moods and a sense of well-being.
By understanding that this is the case, we can avoid taking on big challenges or confrontations on those days when we haven’t had enough sleep the night before, thereby avoiding possible conflicts and disappointments. We can also wait until days we’ve slept well the night before to celebrate our accomplishments, so that we can enjoy the moment that much more. This understanding also helps us to be more patient with our friends, neighbors and co-workers, and maybe not take it too personally when they snap at us for seemingly no reason.
If sleep deprivation continues, emotional problems can become exacerbated. The risk for developing emotional disorders such as depression and anxiety increases. Lack of sleep over time can impair memory, cause us to exercise less and eat less healthfully. We also tend to be less likely to participate in social or leisure activities when we suffer from sleepiness. Chronic lack of sleep affects our relationships, and our work life. In terms of emotions, those few bad days of bad moods can end up turning into weeks as we fall into the habitual lack of sleep. A 1997 study found that insomnia, defined as habitual sleeplessness, or the inability to sleep, increases the risk of a person developing symptoms of depression by more than tenfold.
If you’ve been sleeping poorly or feeling depressed for four weeks or more then it is important to address the problem. Experts say that one of the first signs of depression is difficulty with sleep. Lack of sleep and depression often go hand in hand, and it can be difficult to determine which came first. Many who don’t sleep enough are depressed, and many who are depressed don’t sleep well. The same holds true for anxiety. Anxiety makes it difficult to fall asleep. It also makes it difficult to fall back to sleep when we wake up in the middle of the night. Stress affects us in the same way. It makes the body alert and aroused, in the “fight or flight” mode, so that we can’t relax enough to get to sleep. Depression and anxiety cause us to wake up more often in the night, which means we miss out on the vital deep sleep that the mind and body needs to function optimally.
Another sleep issue that comes with depression is “hypersomnia” or excessive daytime sleepiness (EDS). Hypersomnia is when you sleep too much and have trouble staying awake. People with hypersomnia feel abnormally sleepy even when they’ve gotten adequate sleep. As many as 40% of adults with depression struggle with this.
Treating a sleep issue often reduces the symptoms of depression and anxiety. When we sleep well, we feel good. Good sleep helps us to be happier by nurturing our mental and emotional resilience. Sleep also contributes to a robust immune system which helps the body to stay healthy.
As you can see, mental health and sleep are intricately connected in many ways. Help yourself to maintain emotional health by following the guidelines that the Better Sleep Council recommends for a good night’s sleep including:
– Making your bedroom a sleep sanctuary – keep electronics out, keep the room dark and cool, and invest in a comfortable supportive mattress
– Getting some exercise and sunshine daily
– Getting to bed by 10 pm, and avoiding screen time an hour before bed.
There are many more great sleep tips and articles on the BetterSleep.org website.
If you are concerned that you might be experiencing depression, or if you have been feeling hopeless and constantly tired for more than four weeks, reach out to a mental health professional. Not sleeping enough, or not getting enough quality sleep, despite following sleep recommendations, or feeling sleepy no matter how much sleep you are getting, could be symptoms of depression or anxiety. It is important to see a professional, especially if you are having suicidal thoughts. You can also call one of these hotlines:
Suicide Prevention Hotline: 1-800-273-8255
MentalHelp hotline: 1-888-993-3112

domain: health


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Patio Fridays: Arwen & The Gael
August 31, 2018 @ 6:00 pm - 8:00 pm
Kick off each weekend this summer by The Clock Tower Collective. The patio has live music every Friday 6-8pm. Enjoy drinks, taqueria meals, desserts, and bands. It’s the ideal way to adjust your attitude for a playful weekend in our community. And this is out last Patio Friday of the series!
Arwen and The Gael play Celtic/Eclectic. You probably know The Gael as an acoustic folk band influenced by Irish, Scottish, and Cape Breton tunes. With Arwen on vocals, the band takes their music to a new level of diversity, where traditional Celtic is mixed with Russian cabaret, American pop, Gypsy soul, etc.
Everyone in the group brings in new songs and tunes to add to their ever-changing repertoire. Their show is kind of like the Colorado weather: if you hear something you don’t like, the next tune will likely be different.


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Chickpea Exports From India Record A Better Performance
PANAMA - May 15/19 - SNS -- So far during the calendar year recorded a a better performance, with chickpea shipments for India improved relative to the previous month in February, according to the latest statistics from Directorate General of Commercial Intelligence & Statistics.
Movement reached 9,316 metric tons (MT) for the month, up 1% from the 9,220 MT exported the previous month. Export sales so far total 18,536 MT, versus 27,932 during the previous calendar year.
The most recent trade data reported Algeria was biggest consumer, taking 1,894 MT. Sri Lanka was the second most important buyer receiving 1,324 MT, followed by United Arab Emirates at 787 MT.

domain: economics


Katie Welch is an American Pop-Jazz singer and songwriter based in Los Angeles, with a voice that is a blend of cinematic pop soul and influences including Lana Del Rey and Celine Dion. She has collaborated with a range of talents including producers Just Loud and Chromosomes, DJ Shitty Princess, British Rapper 4N and singer/rapper Eman8. She has performed for audiences at Los Angeles hotspots such as Delilah, Blind Dragon and the HBO Golden Globes after party. Katie won the first season of the Off The Strip singing competition in West Hollywood, CA, and is now the host of the show heading into its fifth season.
Her first EP Typical Psycho was released in 2018, followed by her upcoming album The New Renaissance.


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AB Science SA, of Paris, said it signed an exclusive licensing agreement with the University of Chicago to research prevention and treatment of nidoviruses, coronaviruses and picornaviruses. The collaboration follows the discovery by the university that masitinib inhibits the main protease, 3CLpro, necessary for the SARS-CoV-2 viral replication cycle. AB Science will supply masitinib and more than 130 other AB Science drugs that have demonstrated activity against SARS-CoV-2 main protease 3CL-Pro via virtual screening methodology.
Having received European Commission market authorization for cardiovascular risk reduction in high-risk, statin-treated adult patients who have elevated triglycerides (≥150 mg/dL) and other risk characteristics, Amarin Corp. plc, of Bridgewater, N.J., and Dublin, said it planned to launch Vazkepa (icosapent ethyl) in Germany before the end of the third quarter of 2021. Amarin said it expects to grow its staffing in Europe to approximately 300 people by the end of 2021, with increases planned as market access is expanded in various countries. Vascepa capsules are composed solely of the active ingredient icosapent ethyl, a form of eicosapentaenoic acid.
New preclinical data from Ampio Pharmaceuticals Inc., of Englewood, Colo., suggested Ampion's suitability for addressing kidney diseases and provides further evidence it is a platform biologic for treatment of inflammatory and autoimmune diseases, the company said. The study evaluated Ampion’s ability to suppress TLR7 signaling in order reduce the pro-inflammatory chemokine, CXCL10. Toll-like receptors are a mechanism for innate immune cells to detect and respond to microbial infection. Ampion is a stem cell antigen-1 inhibitor.
ANI Pharmaceuticals Inc., of Baudette, Minn., said it acquired NDAs for Oxistat Lotion, Veregen Ointment and Pandel Cream and the ANDA for Apexicon E Cream from Sandoz Inc., a unit of Novartis AG, of Basel, Switzerland. Pandel Cream will be transitioned later upon receiving requisite approvals. Collectively, the products generated net revenues of $13.2 million in 2020, the company added. The acquisition was funded through the company’s revolver credit facility.
Bavarian Nordic A/S, of Copenhagen, said it received a new supply order from Janssen Pharmaceutica NV, part of New Brunswick, N.J.-based Johnson & Johnson, valued at approximately $28 million. Bavarian Nordic will manufacture and deliver bulk drug substance of MVA-BN Filo vaccine, licensed to Janssen as part of its Ebola vaccine regimen, Zabdeno (Ad26.ZEBOV) and Mvabea (MVA-BN Filo), which was approved by the European Commission in 2020. Manufacturing of the bulk drug substance will commence in May, and delivery is expected to take place in the second half of 2021.
Hoth Therapeutics Inc., of New York, said it engaged the CRO Worldwide Clinical Trials for a phase IIa dose-ranging trial of HT-001 for treating cutaneous toxicities associated with EGFR inhibitor therapy for cancer patients. The study is an investigation of the efficacy and safety of varying dose strengths of HT-001 compared to placebo for treating cutaneous disorders (skin, nails and scalp) associated with EGFR inhibitor therapy. The study will be conducted in cancer patients receiving EGFR inhibitors, inclusive of both small-molecule and biologic drug classes.
Kuros Biosciences Inc., of Schlieren, Switzerland, said it will receive a $2 million milestone payment from Checkmate Pharmaceuticals Inc., of Cambridge, Mass., for dosing the first melanoma patient in a phase II study with vidutolimod (CMP-001, formerly CYT-003). Checkmate is investigating vidutolimod, a Toll-like receptor 9 agonist, across multiple tumor types in combination with checkpoint inhibitor immunotherapies. Vidutolimod was licensed from Kuros in 2015. Kuros stands to receive up to $56 million in development and regulatory milestone payments related to vidutolimod. In addition, Kuros will receive royalties of high single-digit to low-teens percentages on future annual net sales of products covered by a licensed patent.
Maxwell Biosciences Inc., of Austin, Texas, said Pharmaceuticals published a paper co-authored by scientific advisory board member Gill Diamond of the University of Louisville and collaborators showing that peptoids MXB-4 and MXB-9 exhibited in vitro antiviral activity against SARS-CoV-2. When incubated with virus for one hour at 37°C at increasing concentrations, the researchers observed virus inactivation with IC50 values of 20 µg/mL and 7 µg/mL, respectively. Visualization by Cryo-EM confirmed direct disruption of the viral membrane, as previously shown with HSV-1. The researchers also assayed peptoid cytotoxicity against cultured human cells and observed tolerability up to 500 µg/mL, suggesting a good therapeutic window.
Moderna Inc., of Cambridge, Mass., and Catalent Inc., of Somerset, N.J., said they expanded their strategic collaboration by dedicating a high-speed vial filling line to manufacture Moderna’s COVID-19 vaccine (mRNA-1273) and, potentially, other programs from Moderna’s pipeline at Catalent’s biologics facility in Bloomington, Ind. The high-speed line will be dedicated to Moderna’s use through June 2023. Catalent also will provide inspection, labeling, placement in cartons and final packaging for the programs.
Mybiotics Pharma Ltd., of Rehovot, Israel, and the Hadasit Medical Research Services and Development Ltd., part of Hadassah Medical Center, entered a research collaboration and licensing agreement to identify microbiome-based therapeutics for enhancing the response to and reduce adverse effects of anti-PD-1 and anti-PD-L1 in melanoma patients. The research will aim to assess the composition of the gut microbiome and secondary metabolites in up to 100 melanoma patients treated with PD-1/PD-L1 checkpoint inhibitors, some of which already exhibited long-term response to treatment. Stool and blood samples will be collected at various time points along treatment to identify microbiome components.
Oryzon Genomics SA, of Madrid, Spain, said it initiated a preclinical collaboration on autism with researchers from the Seaver Autism Center for Research and Treatment at the Icahn School of Medicine at Mount Sinai, under the direction of Joseph Buxbaum. The effort will explore the effects of vafidemstat, Oryzon’s phase II lysine specific histone demethylase 1 inhibitor and MAO B inhibitor, in models of autism in Shank3 deficient mice models developed and characterized at Seaver by Buxbaum’s team.
Ose Immunotherapeutics SA, of Nantes, France, said a peer-reviewed publication on OSE-230, its preclinical chemokine receptor-like 1 agonist targeting chronic and severe inflammation, was published in Science Advances. The paper showed that the monoclonal antibody reduced tissue neutrophil accumulation and triggered resolution of chronic inflammation of the G protein-coupled receptor that is overexpressed in the inflamed tissues of people who fail to respond to anti-TNF-alpha or anti-alpha-4 beta-7 therapies. The research team observed reduction of fibrosis in inflamed tissues and reduction in development of inflammation-driven tumors. The collaboration included Ose staff and scientific partners at Ambiotis, a French contract research organization; Mabsilico, a French biotech specializing in artificial intelligence; and the Center for Research in Transplantation and Immunology, based at the University Hospital of Nantes.
Oxford Biomedica plc, of Oxford, U.K., said it agreed to a three-year development and supply agreement with Boehringer Ingelheim GmbH, of Ingelheim, Germany, covering the manufacture and supply of viral vectors. Oxford plans to manufacture GMP batches to support Boehringer’s development of viral vectors and may manufacture and supply viral vector products in the future.
Progenity Inc., of San Diego, said it concluded an agreement with Ionis Pharmaceuticals Inc., of Carlsbad, Calif., to evaluate the safety, tolerability and performance of Progenity’s oral biotherapeutics delivery system (OBDS) for oral systemic delivery of antisense oligonucleotides developed and manufactured by Ionis. The OBDS is an ingestible capsule based on needle-free technology designed by Progenity that enables delivery of a drug formulated in solution directly into the tissues of the small intestine, where it can be absorbed systemically. Initially, the companies plan to evaluate the OBDS in conjunction with an Ionis drug in a preclinical canine model to assess in vitro compatibility and performance as well as in vivo safety, tolerability and performance.
Rational Vaccines Inc., of Cambridge, Mass., said it executed a license agreement with Louisiana State University covering work conducted by virologist Konstantin “Gus” Kousoulas from LSU’s School of Veterinary Medicine in the Division of Biotechnology and Molecular Medicine that expands Rational's core mission to eliminate the herpes virus. In animal models, the vaccine technology, known as VC2, showed potential to treat herpes simplex virus 1 and 2 as well as facial and ocular herpes. VC2 is a live-attenuated, engineered version of HSV-1 that prevents HSV from entering neurons of the body.
Sound Pharmaceuticals Inc. (SPI), of Seattle, said it was awarded a $3.1 million cooperative grant from the National Center for Advancing Translational Sciences at the U.S. NIH to support testing of SPI-1005 in two phase II trials involving 120 adults with moderate or severe COVID-19. The oral capsule contains ebselen, a COVID-19 replicase polyprotein 1a/1ab inhibitor and glutathione peroxidase stimulator, in development for neurotologic, neuropsychiatric and respiratory indications. In addition to assessing clinical outcomes, SPI will examine whether the body's inflammatory and cellular immune response to COVID-19 infection will improve with SPI-1005 treatment.
Valeo Pharma Inc., of Montreal, said it inked a letter of intent following negotiations with the pan-Canadian Pharmaceutical Alliance for coverage of Redesca and Redesca HP (low molecular weight heparin biosimilar) to prevent and treat thromboembolic disorders. The agreement enables Valeo to ensure coverage under publicly funded drug plans in Canada.
Yumanity Therapeutics Inc., of Boston, said an in vivo efficacy study of YTX-7739 in a mouse model of glioblastoma multiforme (GMB) showed increased overall survival. The study, conducted by researchers at the Massachusetts General Hospital and presented virtually at the Society for NeuroOncology/NCI Joint Symposium: Targeting CNS Tumor Metabolism, showed the oral stearoyl CoA desaturase-1 (SCD) inhibitor, administered alone or with temozolomide (TMZ), and YTX-9184, a second SCD inhibitor in development by Yumanity, each increased median survival as a monotherapy and showed synergy with TMZ in both aggressive and slow-growing tumors. YTX-7739 is in development by Yumanity to treat Parkinson’s disease.

domain: biology


Fears are growing that some Covid restrictions could remain in place until next spring - as Freedom Day is set to be delayed.
Boris Johnson is expected to agree to put the final easing of controls on hold for up to four weeks when he meets senior ministers on his return on Sunday from the G7 summit in Cornwall.
It could mean that lockdown lifting – which had been due to take place on June 21 as part of the Government’s road map – will be pushed back to July 19.
And Government sources have told The Telegraph they fear the delay could mean some restrictions will remain until next spring as a four-week delay would leave a 'very short window to open up' before winter pressures on the NHS begin.
A senior minister told The Telegraph: "I am very worried the people who want to keep us shut down now want us to shut down permanently and are aiming for 'zero Covid'.
"Once you start delaying to the spring you're making this type of control of people's lives semi-permanent."
One senior Conservative added: "I just don't buy that in four weeks time it will somehow look completely different, and the scientists will say, 'it's fine, you crack on.'"
In an interview with The Mirror, the Prime Minister all but confirmed that it is likely that June 21 would be pushed back to July 19, as Covid cases continued to rise.
They have rocketed by more than a third over the last week to 7,738 - the second-highest daily figure since February after they exceeded 8,000 on Friday.
Mr Johnson said: "We are seeing some worrying stuff in the data, clearly. We are seeing the delta variant causing an increase in cases, we are seeing an increase in hospitalisations.
"The whole point of having an irreversible roadmap is just that, to make it irreversible, and to do that sometimes, as I've said repeatedly, you have to be cautious. And where it's necessary to be cautious, we will be."
Hospitality bosses have said further support is urgently needed if the Government chooses to push back plans to ease pandemic restrictions further on June 21.
Do you think Freedom Day should be delayed? Have your say in the comments here.
Kate Nicholls, chief executive of trade body UK Hospitality, highlighted that thousands of operators will continue to lose money until the last phase of the roadmap out of restrictions.
She said: “Hospitality businesses cannot continue to operate under conditions that leave them unable to trade profitably and so we echo the importance of Government support should there be any delay to the complete lifting of restrictions on July 21.”
Restrictions that are likely to continue until July 19
- Pubs and restaurants won't be able to open to full capacity, with the number of customers allowed in limited by social distancing rules and table service remaining.
- The limit on numbers allowed into arenas, cinemas, theatres sporting events will also remain.
- Rules on face masks will stay in place - for wearing on public transport and inside public venues.
- Nightclubs - which were expected to reopen on June 21 - will remain closed.
- It will mean still only six people can eat together inside, with gatherings of up to 30 people allowed outside.
- Workers are expected to work from home for another month at the very least.
- Reformed drug dealer avoids jail as she's 'now in a great place'
- Chip shop boss in council row over 'uncovered chicken'
- Stoke-on-Trent pub fenced off after not opening for six months
- Potteries ghost hunters on the lookout for haunted locations for their YouTube videos
- 9 coppers who were sacked or jumped before they were pushed
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Photogrammetry is a modern technique of digital capture of real models, which we have already talked about in this blog. Technique we work on rebuilding sculptures or buildings. This technique analyzes a group of photos of a model from different points of view and with them and many triangulation operations we obtain an automatic model in 3D.
The resulting model thanks to 3D printing is not limited to the digital world but can materialize as a sculpture in an automatic process. This is now possible thanks to the current technology, but it was similarly imagined by Fraçoise Willème in 1860. He called it photo-sculpture, a technique that still needed a lot of human handcraft but really dreamed of industrializing sculpture process.left:Photo-sculpture Fraçoise Willème self portrait. right: Photo-sculpture comtesse Walewska
The photo-sculpture came to have a certain fame at the time and portrayed the French imperial court, or the Spanish court of Isabel II by his partner in Spain Jean Laurent. Unfortunately this technique had a high cost and would find the rejection of the majority of the artists of its time who stood against the technological advances that began to dominate their world.
This technique is a clear antecedent of what we do today with photogrammetry. It consisted of taking 24 simultaneous photographs of the person to be portrayed in a room prepared for it. With these photographs and the aid of a pantograph the silhouettes of the model were drawn to the desired scale. These silhouettes were like segments with which a model was built that finally an artist would work to give sufficient detail to the sculpture.left: photo-sculpture studio. right: sculpture from the photos
left: from photo to sculpture. right: patent for photo-sculpture
The most interesting thing is that the material with which they worked, photographs from different points of view is the same as we used in photogrammetry, so the photographic material that Willème and his partners created could serve to create photorealistic models of the high society of the nineteenth century, Creating a link that leaps 150 years in time and technology, linking the era of steam with digital.
In Moøkan we have decided to try to achieve this leap and to honor the work of the French sculptor by searching original files of his studio to be able to process his photographs and reconstruct them in 3D. We hope to be able to update this project soon with new information and if possible some virtual model.


How To Build An Adu In California
The size and number of adu units can be different. Some homeowners may just want some extra space for an office or studio that can also be used as a guest room.
The first step when deciding to build an adu is to determine what type of adu best fits your personal needs, and the physical characteristics of your property.
How to build an adu in california. While construction costs will depend on the design of the home and the quality of the building materials, the average you can expect is about $100 to $200 per square foot. Fees also covered energy modeling per state of california title 24 requirements, and a storm water drainage plan by the civil engineer. 831.227.2217 [email protected] 189 walnut avenue santa cruz, ca 95060 media careers building an adu.
The maximum size for an adu halts at a mere 950 square feet. At openscope studio, we spent the last year designing and engineering several different adu prototypes to streamline the process of adding an adu to your property. California modulars adu home is built with modular construction of the highest quality in mind.
All fees required to plan and build the adu through the city of los angeles. Owners who are just looking for extra room probably don’t need to bother getting all the necessary permits to build an adu. We've compiled an easy list.
Even with a small lot no bigger than 324 square feet of space, california modulars can build an adu on your lot! Adu can be a part of the existing house, conversion of a garage or other structure or build a new structure. Although the city is just a short bart ride from san francisco, walnut creek falls flat with its restrictive requirements.
Adus might be a solution to the california housing crisis, but don’t have to be used to house a person. You’ve landed on the right site! These small houses can be used to keep family close by or even rented out for an extra stream of income.
One way that california counties are starting to address this: So, how do you know if your city is right for an adu? The budget included design fees to cali adu for the adu design and structural engineering.
The key highlights of the new state adu law are summarized below. Want to build your own adu? Our plans include full architectural details that can be used to collect construction bids and handed over to a structural engineer for finalizing and submit for building permits.
Even with all of the updates in legislation throughout california, building an adu on your property can be a time consuming and expensive process. California needs more housing, and homeowners can help by providing additional housing options for our fellow californians. California is a patchwork of differing adu regulations depending.
City and county approved floor plans. Adus have become very popular as a means of increasing property values, generating rental income, and providing affordable housing for. Adubuildingplans.com is the best place to find the perfect floor plan for your adu.
# c33050 ca contractor lic. Walnut creek of contra costa county kicks off our list for the worst cities to build an adu. Ryan o'connell march 27, 2021.
Our focus is streamline your accessory dwelling unit (adu), granny flat, and real estate investment opportunities for your construction project. In 2020, it became easier than ever to build accessory dwelling units in california, thanks to changes in state adu law. We are proud to say we use only the most qualified labor, specifically trained for adu construction.
Paste it into an email and change the name at the bottom to your own name. Built with no compromises in quality, in structural sense our. Available as diy or have turnkey adu complete the entire project.
Address your email to [email protected]


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Authors:J. Delben, A. Delben, K. Miazato, S. Oliveira, and Y. Messaddeq
New fluorindate glass compositions have been investigated in order to improve optical transmission as well as thermal properties.
Chloride inclusion extends transmission of a fluoride matrix to longer wavelength in infrared region. In the present work
thermal parameters of an IZnBS composition, based on InF3, ZnF2, BaF2 and SrF2, with various amounts of alkaline chlorides were investigated by differential scanning calorimetry. The chloride presence
decreased all characteristic temperatures and increased both thermal stability and glass forming ability up to 10% of MCl
content, where M=Li, Na, K and Rb. The presence of NaCl promoted glass phase separation. For samples containing same concentration of NaCl,
this effect is accentuated for increasing the contents of SrF2.
A study was made of the thermal stability of epoxy compounds which were unfilled or contained metallic fillers such as aluminium dust, aluminium flakes, powdered bronze, powdered brass and silver flakes. The properties of the compounds were modified by the use of various hardeners.
derivatives in the chosen models ensure the system's stability. The proposed control law is characterized by several adjustable parameters. The adaptation mechanism used to adjust the parameters is a combination between the MIT and Lyapunov stability methods
groundwater- and river water-level variations (e.g., Schnellmann et al. 2010 ; Mentes 2017b ) on river bank stability. However, to date, the direct effect of hydrological processes on movements and deformations of high river banks (e.g., Uchimura et
Authors:Wantinee Viratyaporn and Richard L. Lehman
properties, particularly its low toughness and poor thermal stability. In the polymerization process the termination reaction of propagating chains can occur either through disproportionation or combination reactions depending on the stability of the
Authors:Jiří Kučerík, Jan David, Martin Weiter, Martin Vala, Jan Vyňuchal, Imad Ouzzane, and Ota Salyk
techniques. Recently, those techniques were used in order to study the stability of DPP N -alkyl derivatives and polymorphism occurring upon fast and moderate cooling of the material [ 8 ].
More recently, the thermogravimetrical analysis of DPP
Authors:Shinn-Gwo Hong, Tsung-Kai Gau, and Shih-Che Huang
– 9 ]. The impressing biodegradation and biocompatibility properties of PHB have resulted in many potential applications of PHB in the industry especially in the medical field, nonetheless, the inherent brittleness and inferior thermal stability (in
Authors:Hieronim Maciejewski, Izabela Dąbek, Ryszard Fiedorow, Michał Dutkiewicz, and Mariusz Majchrzak
resistance and thermo-oxidative stability [ 17 , 18 ]. The high reactivity of the oxirane ring of epoxides makes it possible to obtain a wide range of compounds or organic–inorganic hybrid polymers. Siloxanes are used for the modification of epoxy resins


text: Sun Premade Paper Pieced Embellishments for your scrapbook pages. Each piece cut and hand detailed, using only top quality materials. I accept Paypal only as form of payment and ship USPS First Class Mail upon receipt of payment. I do combine shipping on items purchased the same day. Patterns by LSHD, TBD, KBD, MSC, or CCD.