text:
American who plotted ‘India’s 9/11’ gets 35 years in prison
BY RUMMANA HUSSAIN AND KIM JANSSEN Staff Reporters January 24, 2013 11:39AM
David Coleman Headley | ABC7
Updated: February 26, 2013 6:23AM
Linda Ragsdale looked straight at David Coleman Headley Thursday and told him of the bloody destruction he helped unleash at a luxury hotel in Mumbai, leaving her with a bullet wound and “unbearable” emotional scars.
The Nashville, Tenn. woman was enjoying a meal with her meditation group when a “boy” no older than her own son sprayed The Oberoi hotel with bullets and grenades, killing a Virginia man, his teenage daughter, and countless others.
“I know what a bullet could do to every part of the human body. I know the sound of life leaving a 13-year-old child. These are things I never needed to know, never needed to experience,” Ragsdale said in a wavering voice staring at the terrorist who locked his eyes — one brown, one blue — on the floor.
Headley on Thursday was sentenced to 35 years in prison for his role in the 2008 Mumbai attacks and a foiled plot targeting a Danish newspaper that published controversial cartoons of the prophet Muhammad.
Although U.S. District Judge Harry Leinenweber said Headley, 52, deserves life in prison, the judge said he had to take in account his extensive cooperation with U.S. authorities since pleading guilty following his 2009 arrest at O’Hare Airport.
Headley, who wore a gray sweat suit and black New Balance gym shoes, told the judge in a letter that he was “capable of change,” valued “American” ways and re-read the Islamic scriptures he said were taken out of context when he was swayed by Lashkar-e-Taiba — the Pakistan-based militant organization responsible for “India’s 9/11.”
But Leinenweber said he didn’t have “faith” that the former heroin addict had been transformed and said Headley should be “under lock and key.”
The damage that was done was “unfathomable to the people who survived. Perhaps the lucky ones were the ones who didn’t survive,” the judge said.
Ragsdale was the only victim who testified in court Thursday. She addressed Headley by his given name of Daood Gilani and “not the name he masqueraded” in as he plotted the South Asian attack.
Ragsdale said she remembered the gunfire flash by as she and others hid under the table and saw 13-year-old Naomi Scherr and her father Alan take their last breaths in the devastating carnage.
“Together we faced all of this while you faced a TV screen,” Ragsdale said, referencing Headley’s account of how he watched the three-day bloodshed unfold in front of a television in Lahore, Pakistan.
Earlier Thursday, former U.S. Attorney Patrick Fitzgerald joined prosecutor Daniel Collins, who asked for a 30-to-35-year sentence, to highlight the assistance Headley provided in dissecting a complex international terror web. Headley’s attorney John Theis went a step further to say the “profound” information his client volunteered “saved” lives all over the world.
Outside of court, Headley’s other lawyer, Robert Seeder, assured reporters, “Mr. Headley’s [sealed] letter to the judge expressed his sincere remorse and it was voluminous and it was very clear. He did explain in that letter what led him to this and how sorry he was. I think we’ll leave it at that.”
Acting U.S. Attorney Gary Shapiro said U.S. and foreign officials hope to continually glean more from Headley so others can be prosecuted in the future. Should he refuse, the plea agreement that keeps Headley from being extradited to India would be voided, Shapiro said.
“The number of cooperators you get in terrorism cases is vanishingly small. The object of this exercise for us here in Chicago was to try to balance between the horrific nature of the crime and the future investigations we’re going to be conducting, . . .” Shapiro said.
“I don’t know whether Headley’s proclamations of remorse are sincere and quite frankly, I don’t care. What I care about is that he’s been telling us the truth, and it’s been really valuable and I hope in future cases, it’s a beacon.”
Headley, made headlines when he testified at the 2011 trial of his Northwest Side pal and co-defendant Tawahhur Rana.
Headley admitted acting as a scout for the Mumbai attack and the thwarted plot in Europe while posing as the emissary of Rana’s Chicago-based travel business. While on the stand, he also told tales of how he charmed the likes of extremists, members of the right wing Hindu group Shiv Sena and the son of a prominent Bollywood director while he did his scheming in India.
Though specifics of Headley’s help to U.S. and Indian investigators were detailed only in a sealed court filing, publicly available court papers state that he gave valuable information on Lakshar’s leadership, its planned future terror targets and top-ranking al-Qaida terrorist Ilyas Kashmiri, before Kashmiri’s 2011 death in a drone strike.
Headley and Rana grew up together in Pakistan and remained close, even after Rana moved to Canada and later Chicago, evidence showed.
Rana, 52, was sentenced last week to 14 years in prison for helping Headley plan the Denmark attack and assisting Lakshar.
Authorities Thursday said they hoped there was “some measure of comfort” for Indians here and overseas.
But that didn’t give much relief to Rich Jeswani. Jeswani’s Chicagoan cousin, Sandeep “Sam” Jeswani, was one of the nearly 170 killed in Mumbai.
“He should have gotten life,” Rich Jeswani said of Headley, who was born to an American mother and a Pakistani father who worked for the Voice of America.
“He cooperated because of fear. It’s not just about my cousin. We lost many lives in India.”
Om Arora, 71, who owns Uma Sarees on Devon Avenue, said the sentence was “very, very” fair.
“He [Headley] deserves it for what he has done. I think the chapter is closed [in the U.S].” India and Pakistan “have to do their own part.”
Contributing: Becky Schlikerman


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A free tutorial about how to create the dog face, and free printable pattern pieces for the dimensional muzzle and ears.
The latest from some of our partners:
- Just Arrived - Today's Newest Fabric Collections! 🎉
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domain: design


text:
As Dirty Syringes Pile Up, One N.H. Lawmaker Seeks to Legalize Needle Exchange
New Hampshire Public Radio
January 12, 2016
In Manchester this past year, more than 540 dirty syringes have been found. But as heroin use increases across the state, used needles are also showing up in cities like Nashua, Dover and Laconia.
As part of our series, Dangerous Ends, we look at one bill seeking to legalize needle exchange programs in New Hampshire – a proposal that has been controversial in the state.

domain: politics


Availability: Currently Out of Stock
Starting at $4829
Availability: Call for Availability
Trike of the year 2015
When you sit in the TRIcon 26 for the very first time, it immediately becomes clear why this trike has won the title Trike of the year 2015. Just settle comfortably in the ergonomic seat, sit back and start pedalling. The first two or three corners will give you a taste of the best advantages of our revolutionary 26 rear wheel solution. The shortest possible stiff fork with the 157mm wide Syntace solid through-axle design that we borrowed from mountain bikes, work an absolute miracle. What previously was unthinkable in the world of tricycles with a 26 rear wheel suspension has now become a reality. Yes, we are talking about fast cornering with minimal rear wheel flex while making you feel that the trike is absolutely stable and reacts accurately and instantly to any correction of the direction coming from the handlebars. And this feeling sure is absolutely exhilarating.
Attention to detail, beauty of the whole.
All the above mentioned is complemented by the prized characteristics of the dimensionally smaller but older brother, the TRIcon 20. These include a very comfortable rear suspension due to a genuine cycling shock, perfectly tuned steering, excellent power transmission, comfortable seat and the F2F-U (Fold to Flat Ultra) folding system which allows the trike to be folded not only in half but which also allows the rear fork be rotated below the frame, thus reducing the overall size of the trike when completely folded. Nevertheless, for many people the appearance of their TRIcon 26 is an important factor as well. And in this sense, the trike is truly unique. Emphasis has been placed on details such as the red bowden ends, the removable anodized rear fork dropouts, the wonderful quick releases or the cleverly shaped front wheels caps. The TRIcon 26 simply exudes robustness and healthy aggression.
26 or 20?
Shall I choose a trike with a 20 or 26 inch rear wheel? This is one of the most frequent questions we get asked. Many people just like the look of the 26" rear wheel and for them it is the biggest factor when they are deciding, but there are some objective reasons why to opt for this size as well. The more so when you learn that we in AZUB have managed to eliminate one of the major disadvantages of a 26" tricycle with rear suspension its immense flexion when cornering. The 26" wheel has more inertia and therefore it is better at maintaining speed on flat terrain and when going downhill. It is also easier to find the right combination of gears and components because the 559 size (26") is still more common than the 406 (20"). In addition, a larger wheel provides a higher level of comfort, since due to its size it is better at coasting potholes as the wheel doesnt fall in so much, which in turn also makes the trike a little faster. And when you compare the TRIcon 26 with the TRIcon 20, the 26" wheel in the former gives it a kind of a more grown-up look. If we were to carry on comparing the 20" and 26" TRIcons, we must not forget to mention that the TRIcon 26 offers all the available gimmicks, including the rear Syntace X-12 solid-thru axle or the removable rear fork dropouts not found on the TRIcon 20. Although, technically speaking, there is no real need for them.
Smooth adjustment of the seat
Ever since we started back in 2000, we have always thought that a bike should adapt to the rider and not the other way round. Thats why we used an adjustable seat for our first bike, in which both the angle and the pedal distance were adjustable. With each further development stage, we introduced a more accurate adjustment, until 2013, when we reached a stage of adjusting without positions. This concept is based on a sliding sleeve, which we produce in a straight version for our tricycles and some bicycles, as well as in a curved version for recumbents.
In 2015, we introduced a new folding mechanism we are really proud of. We wanted to create a folding tricycle that would be adequately stiff and whose folding mechanism would be smooth and easy to operate. The feedback from hundreds of AZUB riders has confirmed that we have definitely accomplished what we had planned.
It took us hours and hours of thinking and discussions before we thought up and then designed probably the most sophisticated folding handlebars in the world of recumbent tricycles. We would rather not mention the number of prototypes we have made...
F2F U - Fold to flat ultra
In addition to folding the front part, you can also rotate the rear fork which is designed to fit neatly just below the rear of the frame. This will turn the tricycle into an incredibly small package which you can easily fit into the boot of a small car or into our carry case should you wish to take the trike for example on a plane. And the whole maneuver will take you no more than 5 minutes without the need for any tools.
|Total Weight Capacity||275lbs (125kg)|
|Wheel Track||29.75in (755mm)|
|Total Length||78-88in (1980-2230mm)|
|Total Width||32.8in (835mm)|
|Total Assembled Height||27.5-32in (700-820mm)|
|Ground Clearance||4.6in (117mm) - w/1.5 Tires|
|Folded Size||31x25.5x13.5in (790x650x340mm)|
|Bottom Bracket Height||15.5-18in (400-450mm)|


text:
Our Sofia tote bags made by Turkish artisans feature a unique printed geometric design on a beautiful sand-colored base with a colorful interior. These straps are incredibly durable and will hold up when you’re carrying beach gear or when you want to just make one trip inside after a grocery store run.
Eco-friendly reusable bag, a great alternative to plastic bags
Double-stitched for durability
Features large inside pocket with zipper to store valuables
Unique bold color interior
Bag dimensions: 17.5" X 18" (Height X Width)
Inside pocket: 8.875" X 10"
Comes in Tobacco, Burnt Maroon, or Purple Grey
Made in Turkey
100% pre-washed cotton
You have not selected a page yet. A page can be used for 'About Us' content, contact information, and more.


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Dream Lake, Rocky Mountain National Park. The day before, there was two feet of snow here.
Last light on the Great Sand Dunes National Park
A touch of fall color along Ouray County Road 9, Ridgway, CO
Post-sunset at Maroon Lake. Aspen, CO
Alpenglow above Mohawk Lake, Breckenridge, CO
Cooper Lake, Lake City, CO
9:30 PM, Eleven Mile Reservoir State Park, Lake George, CO
Mt Princeton as seen from Mt Antero, Freemont County, CO.
First light on Quandary Peak, Mohawk Lake, Breckenridge, CO
The setting sun casts its rays on the Sangre de Christo Mountains, Great Sand Dunes NP
4th of July weekend, Slate River, Crested Butte, CO
Ouray County Road 5, Ridgway, CO
Sun's rays and sunflowers over the 4th of July weekend, Crested Butte, CO
Colorado Springs Inversion from Barr Trail.
Sunrise Mohawk Lake, Breckenridge, CO
Hallett Peak, Rocky Mountain National Park.
Wilkerson Pass overlooking South Park, CO
Mt Sneffels Wilderness, Ridgway, CO.
Sunset at Upper South Colony Lake with Crestone Needle and Broken Hand Peaks.
Pre-dawn at Diamond Lake, Indian Peaks Wilderness...with Venus to the east.
Mountain Goat at Mohawk Lake, Breckenridge, CO
Arkansas River, Texas Creek, Colorado.
Pikes Peak as seen from Wilkerson Pass.
Waiting for the blood moon & eclipse. Wilkerson Pass, CO.
Windy Ridge Bristlecone Pine Scenic area, Park County, CO. Some trees in this stand are over 1,000 yrs old.
Bristlecone Pine, Windy Ridge Scenic Area, Park County, CO
New Castle Buford Rd., Rio Blanco County, CO
Routt County Road 14, Steamboat Springs, CO
Crystal Creek, Green Mountain Falls, CO
2015 Fowler-Hilliard Hut trip - Vail Pass Winter Recreation Area
Sprague Lake, Rocky Mountain National Park
Medano Zapata Ranch, Mosca, CO
Early sunset, Rampart, Reservoir.
Sunset, Rampart Reservoir, Woodland Park, CO.
When nighttime and sunrise collide. Kiowa, CO.
July on the East River with Mt. Belleview in arrears. Gothic, CO
London Mountain, Park County, CO
Pennsylvania Mountain as seen from the South London Mine, Park County, CO
Sunset after a heavy rain, Rampart Reservoir . Woodland Park, CO
Long exposure sunset, Eleven Mile Reservoir, Lake George, CO
Brush Creek, Crested Butte, CO
Sunrise, Picket Wire Canyon, Comanche Nat'l Grassland, CO. Nearly stepped on a rattlesnake after this shot!
Kiowa, CO. Sigma 15 mm fisheye.
From Recent Work

domain: geography


text:
Describe the data that needs to be collected about the care process, professionals involved, patients and their health outcomes. These include: e.g. clinical indications, specified populations, prescriber information, inpatient or outpatient use, test results, review period, and health outcomes. In case of new technologies, EVIDENT database could be consulted.
Sources: Local authorities and legislation, administrative staff, clinical professionals, HTAs, National or local judgement.
Liberati A. et al. 1997; Busse R. et al. 2002; Kristensen FB et al. 2001; Draborg E et al. 2005

domain: medical


text:
Having spent countless hours on NBA 2K14, I'm eagerly awaiting the release of NBA 2K15. And that's not just because my team, the Cavs, is assembling a monster of a team with Kyrie Irving, Lebron James, and Kevin Love. That's just a bonus.
One of the teams the Cavs could meet in the NBA Finals (Yes, I'm saying it now.) is the Oklahoma City Thunder. Reigning NBA MVP Kevin Durant is the cover athlete and 2K Sports has released a quick preview of him in action.
The game does look like a step up from last year's version with a very nice looking Durant dunking on Andre Iguodala. October 7th will be the release date for NBA 2K15 on most platforms.

domain: sports


SEWALL'S POINT — The Treasure Coast Council of Local Governments recently met at the Dolphin Bar and Grill north of Sewall's Point for its annual Installation Luncheon, Outgoing chair and mayor of Sewall's Point, Jacqui Thurlow-Lippisch swore in commissioner Richard Gillmor of Sebastian as the 2012 chairperson, and Indian River County commissioner Peter O'Bryan as vice chair. Council Member Dowling Watford of Okeechobee will continue as Treasurer, and Alderwoman Ingrid Van Heckken of St Lucie Village will continue as secretary. The Treasure Coast Council of Local Governments is represented by county, municipality, and school board elected officials from Indian River, St Lucie, Martin and Okeechobee Counties. The mission of the group is to build a sense of cohesiveness and regionalism among the government agencies of the Treasure Coast.
This story is contributed by a member of the Treasure Coast community and is neither endorsed nor affiliated with TCPalm.com
- Sewall's Point commissioner elected to Harbor Branch Oceanographic Institute's Foundation Board Published 2/4/2013 at 3:51 p.m.
- River Kidz plans Help the Rivers Art Show at Harbor Bay Plaza Published 10/24/2012 at 5:29 p.m.
- River Kidz protest House Bill 421 Fertilizer preemption bill Published 2/7/2012 at 12:38 p.m. 0 comments
- Joined September 22, 2011
- Contributed 8 stories
- Posted 24 comments


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|I inquired about the Matrix for a Focal Point gas fire as I wasn't sure if it was the correct one and kindly MYtub assistants enquired for me to Focal Point to make sure it was the correct part. I then ordered the part and could trace its progress on Mytubs web site, which I found very useful. Mytub kept me up to date on the order through emails also. I quickly received the part via a courier which was very well packaged as the parts were delicate and were in perfect condition. Thank you Mytub.
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However, customer services dealt with it quickly and efficiently, calling me back to keep me updated. Item was then delivered the next day.
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|Without this company we would have to have bought a new boiler. They were the only people to stock the part on an old but very usable boiler. Excellent communication and service. Would highly recommend them
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|couldnt find the product any where else at this good price, recieved items in perfect condition, delivery was as discribed, thank you
...arthur llewellyn jenkins


text:
Three a.m. and you’re smoking, Dear,
(and so am I). One shared-cigar
and music--something extravagant
romantic, pours from a bag lady's
mouth as her handcart jumps fish-silver
at the sidewalk's buckled vertebrae
where the Chinese New Year tunneling
underground marches the dragon's collaborative
concrete spine to the end of the block.
Outside The Black Tulip we collect
our affections like rainwater
and then hold the canteen
of each other for the certain thirst.
We treat our love like our houseplants,
making them wait so long,
they slouch toward the sink
before we finally give in
and hand them a drink.
Inside the black tulip:
night-lit, visceral, every color of hurt,
of scabs, the dried injury’s memory
of what it meant to tear open,
a space like that within praying hands.
Inside the black tulip, a small room
where a tiny family might gather
around the dollhouse television
as if it were a fire. The president
might present the queen with an i-pod
and we’d think it surreal only here,
where the black tulip chimes
the hour of Plato’s worst fears,
to name a thing is to make it possible,
to make it possible invites the lie.
Outside The Black Tulip, our breath
braids tequila and rum, and someone
tells someone of how today the queen
was given an i-pod by the president
and for a minute, in another realm, Plato
and Einstein raise their glass across
the mushroom clouds of paradise
as an imaginary family inside an imaginary
flower, grown in an imaginary (impossible)
shade of night, points their imaginary
remote control at their tiny screen
and shuts our whole world down.

domain: artistic


text:
Beloved Pagham pond rescued by Portsmouth Water top-up
Lakeview pond, in Pagham, was rescued by residents and a Portsmouth Water technical team after it started to dry up last week.
All that was left of the pond by Friday, when the Portsmouth Water team finally arrived, was a 'slimy green sludge’, according to resident Georgina Steen.
The pond is home to a number of wild animals, including ducks, swans, cygnets, eels and birds – many of whom where endangered by the sudden loss of water.
Desperate to save them, many residents described leaving food and buckets of water for the animals, trying to keep them as safe as possible until a real solution revealed itself.
“Everybody was devastated to see what happened. It was so dreadful to watch,” said resident Jo Robertson. “The ducks and the swans could fly out, but the cygnets couldn’t and neither could the ducklings or the moorhens. So we had to fill up a bath with water and put it in there for them to use.”
By Friday, a Portsmouth Water technical team arrived to top up the pond’s water, making it safe for the wildlife once again.
At the time, a spokesperson for Portsmouth Water said filling the pond was more complicated than merely raising the water level: “Whilst in the past, as a goodwill gesture, we have topped up the pond from our network this, current hot dry spell has meant we have had to think very carefully about helping again. Our underground water resources are under pressure following a period of very low rainfall dating back to January - and as a result of this we have been appealing to our customers to 'use water wisely'. Indeed the Bognor area in general has been a focus of much of our effort recently due to the high demands in the peak holiday season. So we have had to balance the needs of our customers and the environment," they said.
Thankfully, a viable solution was found, but Portsmouth Water has warned it is ‘not as long-term solution', urging residents to ‘work with the owner of the pond to find a permanent solution to the ponds’ vulnerability in dry weather.”

domain: news


text:
THE Capitol needs to ask its officials and employees to refund a total of P29.91 million in incentives they received in 2014, the Commission on Audit (COA) said.
“The Provincial Government of Cebu granted productivity enhancement incentives (PEI) to its employees at the rate of P22,000 or one month’s salary, whichever is higher, contrary to the maximum amount of P5,000 as prescribed under Executive Order 80,” COA said.
It pointed out that the Province spent P37.495 million on the PEI last year, instead of the maximum P7.585 million.
It recommended that the Capitol ask each of its employees who received P22,000 to give back P17,000. Those who received more would have to refund anything beyond P5,000.
State auditors also asked the Capitol to “observe strictly the limitation on the grant of PEI.”
The Capitol had tried to explain that under Section 9 of Department of Budget and Management Circular 2013-3, it is the Provincial Board that should determine how much PEI can be granted, “depending on the local government unit’s financial capability.”
COA also quoted the Provincial Budget Office as saying that the P5,000 ceiling did not apply to offices with fiscal autonomy, as well as government-owned corporations and government financial institutions.
Acting Provincial Budget Officer Danny Rodas told reporters that COA erred in citing EO 80 as its basis for granting the PEI, as this applied only to government agencies.
He said it’s DBM Circular 2013-3, particularly Section 9, that should be used as the basis for granting the incentive to local government employees.
Rodas said he already submitted a response to the Provincial Legal Office, which will, in turn, answer COA.


text:
Voters in Humboldt County last week soundly rejected a ballot measure that would have tightened regulations on the area’s famed cannabis industry. Known as Measure A, the initiative was defeated at the polls on March 5, with more than 73% of the voters casting their ballot against the proposal.
Genine Coleman, the executive director of Origins Council, a group representing California’s legacy cannabis growers, wrote in an email to High Times that the “defeat of Measure A demonstrates that the grassroots cannabis industry in Humboldt County is politically organized and effective, thanks to the Humboldt County Growers Alliance and their successful ‘No on A Campaign.’”
Had it passed, Measure A would have changed Humboldt County’s regulations for cannabis cultivation in a manner that opponents of the initiative say would have likely destroyed the local industry. The proposal was created and advanced by Mark Thurmond and Elizabeth Watson, residents of Kneeland, an unincorporated community in Humboldt County, the epicenter of California’s infamous Emerald Triangle cannabis cultivation region.
Measure A would have added several restrictions on cannabis cultivation businesses to the county’s planning regulations, ostensibly for environmental purposes. New rules would have included a cap on the size of weed farms at 10,000 square feet, a change that would have made more than 400 cultivators noncompliant with county regulations, according to a report from MJBizDaily. The ballot measure also would have prohibited noncompliant businesses from expanding their operations, including increasing water or energy use or expanding the space or buildings used for cannabis cultivation.
Additionally, the defeated ballot measure would have required public hearings for cannabis cultivation operations exceeding 3,000 square feet. The proposal also would have restricted weed farms located on two-way roads designed to accommodate traffic traveling at speeds of 25 to 40 miles per hour.
Measure A was fiercely opposed by many members of Humboldt County’s cannabis community, who feared that passage of the initiative could cripple the local cultivation industry. Some referred to the proposal as the “Karen Initiative” because a group of neighbors began work on the ballot measure after a cannabis grower set up a new operation in their community.
Humboldt Pot Growers Welcome Election Results
The voters’ rejection of Measure A at the ballot box was welcome news for Humboldt County’s cannabis community. Dylan Mattole, a cannabis farmer and chairman of the Humboldt County Growers Alliance (HCGA), said that the members of the trade group were encouraged by the results of the election.
“There’s a feeling of relief from knowing that our community accepts us and that we’re not going to have to keep fighting for the right to do business,” Mattole told SFGATE.
Mattole said that cannabis businesses spent $150,000 on the campaign to defeat Measure A. Although the fight against the initiative was an ordeal, he cited bringing the cannabis community together as a positive outcome of the situation.
“I feel like we’ve really advanced our standing in the community through this terrible situation,” Mattole said. “The silver lining in all this is that I think we actually advanced … the normalization of cannabis as just part of the normal business community.”
Watson, one of the lead proponents of Measure A, said that the results of last week’s election were not unexpected. The initiative was widely opposed by members of the community, including Humboldt County Sheriff William Honsal, three of five county supervisors and city and tribal leaders, as well as the Republican, Democratic and Green political parties. Environmental groups including Cannabis for Conservation also registered their opposition to the ballot proposal.
“When the environmental organizations and all the elected officials came out against it, that was pretty much the kiss of death,” Watson told the Times-Standard.
Watson said that she spent a quarter of her life savings on the campaign to pass Measure A. However, it was not enough to overcome the resources mustered by the campaign to defeat the initiative.
“We were just totally outgunned financially and did the best we could,” she said.
“I’m 76, you can’t take it with you,” she added, saying that she would probably have donated a similar amount of money to environmental groups.
As the defeat of Measure A became apparent on election day, opponents of the initiative also said they were not surprised by the results.
“We were definitely seeing a lot of support leading up to the election. So I think we felt pretty confident going into it,” said Ross Gordon, policy director for the HGCA. “But, of course, we didn’t know until we knew, and so I wouldn’t say it was shocking, but I think we were definitely happy to see that number.”
Gordon acknowledged that cannabis regulations should be reviewed continually. But he added that the process should be a collaborative effort that includes members of the cannabis industry.
“I think it’s been really unfortunate that for the past year or so, we’ve really had to focus on just maintaining the status quo,” said Gordon. “And I don’t think the status quo for small farmers is amazing right now. And I really think we need to be working on more hopeful affirmative projects,” he said, noting the organization’s support of AB 1111, a state Assembly bill that would allow small cultivation businesses to sell cannabis at events.


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Año Nuevo State Park’s rich variety of natural and cultural resources draws visitors from around the world. The park’s Natural Preserve offers an extraordinary wilderness experience, where every year up to 10,000 elephant seals return to breed, give birth, and molt their skin amongst the scenic dunes and beaches.Plan a trip to Pescadero easily and quickly by telling Inspirock to suggest an itinerary.
The park features the Marine Education Center boasting a natural history exhibit, bookstore, and theater. This complex is housed in the historic nineteenth century dairy ranch of the Dickerman/Steele family. These restored buildings recall the early American settlers, while the midden sites throughout the Natural Preserve tell us the story of the Quiroste Indians that lived peacefully here for thousands of years prior to the 1600s. Cove Beach is a short walk from here for beachgoers and surfers.
The physical terrain of Año Nuevo is distinctive, with coastal terrace prairie, wetland marshes, dune fields and coastal scrub hosting a high diversity of plants and animals, including the rare and endangered San Francisco Garter Snake and California Red-legged Frog.
A hike out along ocean bluffs brings visitors to Año Nuevo Point, a major bird migratory route and fantastic birding location. Located just offshore sits Año Nuevo Island and the remains of a 19th century lighthouse and fog signal station. Built in 1872, the historic keeper’s house now provides a new home to Brandt’s and Pelagic Cormorants as well as California Sea Lions. Otters and harbor seals are often sighted in the waters and magnificent Steller Sea Lions take up residence on the outlaying rocks.
Ano Nuevo State Reserve Reviews
This place has limited opening times so plan ahead accordingly. I was disappointed as in my visit there weren’t many seals and they weren’t that Close. But ur really depends on when you visit. July wa... more »
Meravigliosa esperienza tra i giganteschi elefanti marini. La loro stazza fa veramente impressione, come il loro strano verso. La guida personale ti accompagna passo passo spiegando le abitudini di qu... more »Wonderful experience among the gigantic sea elephants. Their size really makes an impression, like their strange verse. The personal guide accompanies you step by step explaining the habits of this species of mammoth seals that come to winter in this beautiful nature reserve. Outside the usual tourist routes, the tours are always with a fair number of people and the guide devotes the right time to the visit without haste. To visit absolutely if you pass by here.
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I work with several companies and links to any products within posts are affiliate.
I’ve always bragged to Zach that I will outlive him since women live longer than men do! Now that I have a son I find the differences between women and men (boys and girls in this case I guess) so interesting. I stumbled across an article in Parents magazine and thought I’d share! And of course I included some pictures of Kye doing the typical boy thing…playing with a ball 🙂
- are four times more susceptible to hip dysplasia where the thighbone dislocates from the hip socket
- more likely to leak breast milk from their nipples as newborns due to high levels of Mom’s estrogen
- get more UTIs
- twice as likely to get asthma
- five times as likely to be born with hemangiomas (raised red spots)
- feel pain and discomfort more acutely than boys so are more likely to cry or fuss
- produce more of the human-bonding hormone (oxytocin) and the feel-good hormone (serotonin)
- less active style of play, stay closer to adults, engage in fantasy and play in small groups
- typically master the potty four months earlier (35 months old)
- more likely to be fascinated by objects with interesting colors and textures
- reach 50% of adult height at 20 months old
- at 18 months vocabulary averages 90 words
- weight less at birth (average is 7lb 4 oz)
- are eight times more likely to be born with a hernia
- four times as many boys are affected by autism
- three times as likely to be diagnosed with ADHD
- more likely to have dyslexia or delayed speech
- don’t hear as well but are better at determining the location of a sound
- explore things more physically yet also have more fluid in their brains to protect their heads from impact
- gravitate towards packs of playmates and intense active games that involve lots of running and chasing
- weigh 4 ounces more on average at birth (average is 7 lb 8 oz, bigger because women pregnant with a boy typically tend to consume 10% more calories!)
- more interested in playing with things that move like toy cars and trucks
- reach 50% of adult height at 24 months old (late bloomers)
- reach puberty 2 years later and tend to continue growing for an additional three years
- at 18 months vocabulary averages 40 words (but catch up to girls by age 3)
- have larger area of brain devoted to visual-spatial relation so master advanced movements (aiming a throw, kicking a ball, building towers) at a younger age
- master the potty 4 months slower (39 months old)
throwing the ball to Mommy!
I thought this was so interesting! Especially the fact that women pregnant with boys consume more calories!!! Does that mean if I have a baby girl that I won’t gain so much weight? That’d be awesome! 🙂 I really feel like that boys have the shorter end of the stick. Girls seem to be healthier and more ahead in life overall. While it makes me happy because I’m a woman, it makes me feel sorry for my son and a little nervous too. The whole autism thing is SO scary! One statistic they missed? Boys are also more likely to be color blind than girls! 1 out of every 20 men are color blind…crazy huh?
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domain: psychology


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If your trip to Huixquilucan is all sorted out but your itinerary is a bit on the empty side, let us give you a helping hand.There’s nothing like discovering new places. While you’re staying in the area, Paseo Interlomas and Centro Santa Fe should be among them. One more sight to keep in mind is Parque Nacional Desierto de los Leones.
If you’ve ticked off all the major sights in Huixquilucan, you won’t want to pack away those comfy sneakers just yet. You’ll find big-name attractions just a little further out. Teotihuacan Archaeological Site is well worth a day trip. You’ll find it in Teotihuacan, 35 miles away.
If you have some important work-related business to see to in Huixquilucan, there’s a high chance you’ll be spending a lot of time in a major convention center. If that’s the case, you might like to know some of the ones that have hotels and restaurants nearby:
Expo Santa Fe Mexico (6 miles away).
Centro Citibanamex Convention Center (8 miles away).
Pepsi Center (11 miles away).
No other mode of transportation can offer you freedom and convenience like your own wheels. No matter the reason for your adventure to Huixquilucan, CarRentals.com has a fantastic selection of vehicles for you to pick from. Heading to the city with your beloved? Turn up the romance by renting a mini or convertible. Loads of fun to drive and easy to park in tight spots, you’ll adore sitting alongside each other in one of these zippy rides. An SUV is a great choice for big families. There’s loads of space for everyone and you can go wherever you want, when you want. If you’re traveling for business, a premium car will get you from conference to meeting in luxury and comfort.
You’ll be happy to hear that there’s a great range of luxury rental vehicles on offer in Huixquilucan. What you go for depends on how much you’re willing to spend and what you plan to do. Specialty vehicles are hard to beat if you’re all about comfort and class. If you’re splurging, why not pick a fully kitted-out SUV, or perhaps a stylish mid-sized vehicle? On the other hand, if you just need a set of wheels to get you around town at the cheapest price possible, stick with a no-frills compact vehicle (or something else that won’t break the bank).
In Huixquilucan, you’ll have to keep on the right side. When exploring a new place, it’s smart to select a car with automatic transmission. That way, you can concentrate on the road ahead and not stress about gear changes.
Finding a car space in Huixquilucan shouldn’t be too difficult. Of course, it can depend on where you are and when — you may have trouble parking in the very center during busy periods.
Since the population of Huixquilucan is around 124,800, you won’t have a lot of difficulty with traffic congestion. That said, major roads are generally busier before and after work hours, so you may want to avoid driving then.
While cruising through the streets of Huixquilucan, keep in mind that the speed limits range from 60km/h to 110km/h. Residential areas are 60km/h unless signed otherwise.
One of two things will happen. Your rental company may bill the amount of the fine to your credit card. This is the more common practice. Alternatively, it may give your contact details to local authorities so the fine is issued to you directly.
It is illegal to use your cell phone while cruising in your car around Huixquilucan, and you may also receive a fine for just holding a phone if you’re in control of a vehicle. That being said, the use of hands-free or Bluetooth functions is permitted, as long as your attention remains on the road.
The legal BAC (blood alcohol content) limit when operating a vehicle in Huixquilucan is 0.08%. If you’re planning on partying, leave the car behind and organize some other way of getting home instead.
No, it’s not. In Huixquilucan, red equals stop, with no exceptions. When approaching traffic lights, always maintain a safe speed so you can easily stop when you need to.
Although there are a small number of exceptions, seat belts must be fastened in State of Mexico.

domain: travel


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Pro-inflammatory Cytokines and Oxidized Low-Density-Lipoprotein in Patients With Fibromyalgia
Funda Canpolat KUTU1, Şenay ÖZDOLAP2, Selda SARIKAYA2
1Department of Physical Medicine and Rehabilitation, Çaycuma State Hospital, Zonguldak, Turkey
2Department of Physical Medicine and Rehabilitation, Medicine Faculty of Bülent Ecevit University, Zonguldak, Turkey
Keywords: Cytokines, fibromyalgia, oxidative stress, oxidized-low-density lipoprotein, pain
Objectives: This study aims to evaluate the differences in serum levels of tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), (IL-8), and oxidized low-density lipoprotein (Ox-LDL) between female fibromyalgia (FM) patients and healthy females and also to examine a possible relationship between the cytokines/biomarker and the severity of pain and clinical features of FM.
Patients and methods: This case-control study included 48 female patients (mean age 26.51±6.98 years; range, 18 to 50 years) who were diagnosed with FM according to the American College of Rheumatology criteria and 43 healthy female subjects (mean age 23.93±4.22 years; range, 18 to 50 years). Serum levels of TNF-α, IL-1β, IL-8, and Ox-LDL were measured by enzyme-linked immunosorbent assay in both groups. Fibromyalgia Impact Questionnaire, Visual Analog Scale, symptom severity scale, and widespread pain index were carried out and also their relationships with TNF-α, IL-1β, IL-8, and Ox-LDL levels were evaluated.
Results: There was no difference in levels of the serum TNF-α, IL-1β, IL-8, and Ox-LDL between FM patients and healthy controls (p>0.05). The severity of pain was significantly associated with TNF-α (r=0.338; p=0.021) and IL-8 (r=0.299; p=0.043) levels, and Ox-LDL (r=0.415; p=0.006) level was found to be related to symptom severity of FM.
Conclusion: Our results suggest that serum levels of TNF-α and IL-8 may be involved in the occurrence of pain in FM. The level of Ox-LDL may play an important role in the severity of symptoms. Future studies are needed to determine whether and how Ox-LDL plays a role in FM.
Fibromyalgia (FM) is a common musculoskeletal disorder characterized by chronic widespread pain, joint stiffness, multiple tender points, and systemic symptoms (i.e., cognitive dysfunction, fatigue, sleep disturbances, and mood disorders) without an underlying organic disease.(1) It affects nearly 5% of the overall population worldwide, indicating that it is one of the most common rheumatic diseases, and females are nine-times more susceptible to FM than males.(2)
The pathophysiology of FM has not been completely understood and there are no established etiological factors. The fundamental pathophysiological mechanism of FM has not yet thoroughly been explained even though many studies have been conducted. It has been suggested that FM symptoms originate from the interactions among autonomic nervous system, hypothalamus-pituitary-adrenal (HPA) axis, and immune system.(3)
Although FM is accepted to be a non- inflammatory disease, it has been considered that cytokines play a role in its etiology since an earlier study by Wallace in 1988.(4) An imbalance of pro-inflammatory and anti-inflammatory cytokines has been proposed to be involved in pain induction and maintenance. However, several studies have shown contradictory results in cytokine levels in this patient population.(5) Besides, it has been shown that cytokines are engaged with the communication between the immune and nervous systems.(6) In addition, several studies have suggested that there is a connection between several cytokines (tumor necrosis factor-alpha [TNF-α], interleukin-1 beta [IL-1β], IL-6, IL-8) and some of the symptoms of FM including hyperalgesia, fatigue, sleep disorders, cognitive dysfunctions, anxiety, and stress.(7-9) However, how cytokines affect the functions of the central nervous system and what their roles are in creating widespread pain in FM are still the questions to be answered.
In recent studies, some evidences have suggested that oxidative stress may also have a role in the pathophysiology of FM.(2,10) In patients with FM, oxidative stress biomarkers have been significantly found to be elevated.(11,12) Oxidized low-density lipoprotein (Ox-LDL) is one of the markers of oxidative stress which identifies an association between the immune system and abnormal inflammation.(13) Pro-inflammatory effect is one of the features of this lipoprotein which also increases inflammatory cytokine production in addition to cell adhesion, migration, proliferation, and apoptosis.(13,14) Circulating Ox-LDL increases in certain diseases which are associated with high oxidative stress and inflammation.(15) These results have led us to investigate the expression of cytokines, as well as Ox-LDL in FM. Therefore, in this study, we aimed to evaluate the differences in serum levels of TNF-α, IL-1β, IL-8, and Ox-LDL between female FM patients and healthy females and also to examine a possible relationship between the cytokines/biomarker and the severity of pain and clinical features of FM.
Patients and Methods
A total of 318 female patients aged between 18 and 50 years who were diagnosed with FM based on the American College of Rheumatology (ACR) 2010 criteria(16) in the Zonguldak Bülent Ecevit University, Medicine Faculty, Department of Physical Medicine and Rehabilitation between May 2013 and May 2014 were screened and 48 (mean age 26.51±6.98 years; range, 18 to 50 years) were included in this study according to ex-in-criteria. The control group consisted of 43 healthy female hospital workers (mean age 23.93±4.22 years; range, 18 to 50 years) who did not have any systemic disease.
Inclusion criteria for both groups were as follows: (i) patients aged between 18 and 50, (ii) having no systemic disease other than FM, (iii) being diagnosed with FM for the first time, (iv) being treatment-naive for FM, and (v) having no medication within the last three weeks for any reason. Exclusion criteria were the presence of any inflammatory autoimmune disease, cardiovascular, neurologic, renal, metabolic and endocrine problems, pregnancy or breast-feeding, and a diagnosis of FM in the control subjects.
Demographic characteristics of both FM patients and healthy controls were recorded and the body mass index (BMI) was calculated for each individual (kg/m2). The pain severity was assessed using the visual analog scale (VAS)-pain scores (0-10 cm). The numbers of tender points were counted according to the digital palpation which is performed by pressing the tender areas with approximately 4 kg/cm2 pressure, until the pulp of the thumb whitened. For a tender point to be positive, the subject must state that the palpation is painful. Tender points count (TPC) was carried out according to the ACR 1990 FM diagnosis criteria.(17) The Widespread Pain Index (WPI) and Symptom Severity Scale (SSS) scores of each patient were calculated according to the ACR 2010 FM diagnosis criteria.(16) In addition, functional status and disease severity of the patient group were evaluated using the Fibromyalgia Impact Questionnaire (FIQ).(18) This instrument was found to be reliable and valid in Turkish female FMS patients.(19)
Blood samples of the patient and control groups were drawn after an overnight fasting. The levels of TNF-α, IL-1β, IL-8 ELISA assays (Platinum ELISA; eBioscience, San Diego, California, USA), and Ox-LDL (Biomedica, Baster, Vienna, Austria) were measured using the enzyme-linked immunosorbent assay (ELISA) according to the manufacturer's instructions.
A written informed consent was obtained from each participant. The study was approved by the Ethics Committee of Bulent Ecevit University (2013-32-26/02), Zonguldak, Turkey, and was conducted in accordance with the principles of the Declaration of Helsinki.
Statistical analysis was performed using the IBM SPSS version 19.0 software (IBM Corp., Armonk, NY, USA). Continuous variables were expressed in mean ± standard deviation or median (min-max) values, while categorical variables were expressed in number and percentage. Normality of the distribution of the data was analyzed using the Shapiro-Wilk test. Continuous variables were compared using the independent sample t-test or Mann-Whitney U test, while categorical variables were compared using the Yates corrected chi- square test or Fisher’s exact chi-square test. The Spearman’s correlation analysis was performed to examine the relationship between the continuous variables. Linear regression was performed for multivariate analysis. P values of less than 0.05 were considered statistically significant.
A total of 48 FM patients and 43 healthy individuals were included in this study. The mean age was 26.51±6.98 years and 23.93±4.22 years in the patient and control groups, respectively, indicating no statistically significant difference between the groups (p=0.159).
The mean BMI was 21.65±3.32 kg/m2 in the patient group and 21.80±3.38 kg/m2 in the control group, indicating no statistically significant difference between the two groups (p=0.993). Demographic characteristics were similar between the groups (Table 1). However, the WPI, SSS, VAS, FIQ, and TPC scores were statistically significantly higher in the FM group compared to the control group (p<0.001) (Table 1). According to linear regression analysis, WPI and TPC were significant predictors of SSS.
|Demographic data and clinical variables||FM patients (n=48)||Healthy controls (n=43)|
|Body mass index (kg/m2)||21.7±3.3||21.8±3.4||0.993|
|Visual analog scale score||5.7±2.0||1.3±1.9||<0.001|
|Symptom severity scale score||7.1±1.9||1.4±1.6||<0.001|
|Widespread pain index score||9.9±3.1||1.0±1.3||<0.001|
|Tender points count||13.9±2.3||0.9±1.2||<0.001|
|Fibromyalgia impact questionnaire score||50.3±14.5||22.0±13.9||<0.001|
|FM: Fibromyalgia; SD: Standard deviation.|
In this study, there was no statistically significant difference in the levels of serum pro-inflammatory cytokines (TNF-α, IL-1β, IL-8) and Ox-LDL between the patient and control groups (p>0.05) (Table 2). However, there was a significant positive correlation between the VAS scores and serum IL-8 and TNF-α levels (r=0.299, p=0.043; r=0.338, p=0.021, respectively) in the FM group. Although the strength was weak, a significant positive correlation was found between the Ox-LDL levels and SSS scores of the patients in the FM group (r=0.415, p=0.006) (Table 3). Correlations between serum cytokines and clinical variables in the FM patients are shown in Table 3.
|FM patients (n=48)||Healthy controls (n=43)|
|Tumor necrosis factor alpha||75.0±59.2||95.5±57.2||0.144|
|Oxidized low density lipoprotein||11.7±16.6||6.8±5.1||0.379|
|FM: Fibromyalgia; SD: Standard deviation.|
|Visual analog scale score||0.338*||0.192||0.299*||0.221|
|Symptom severity scale score||0.138||0.191||-0.005||0.415*|
|Widespread pain index score||0.085||0.099||0.007||-0.020|
|Tender points count||-0.079||0.111||-0.161||0.175|
|Fibromyalgia impact questionnaire score||0.274||0.024||0.279||0.049|
|TNF-a: Tumor necrosis factor-alpha; IL-1b: Interleukin-1 beta; IL-8: Interleukin-8; Ox-LDL: Oxidized low-density lipoprotein; * p<0.05.|
In this study, the levels of serum pro-inflammatory cytokines (TNF-α, IL-1β, IL-8) and oxidative stress biomarker (Ox-LDL) were investigated in patients with FM and compared with the control group. The levels of serum pro-inflammatory cytokines and Ox-LDL in the patient group were similar to the healthy individuals. The levels of TNF-α and IL-8 were related to pain severity. In addition, Ox-LDL levels of the patients were related to severity of symptoms.
In the literature, controversial results in several studies investigating serum pro-inflammatory cytokine levels in patients with FM have been reported. Some authors have reported normal TNF-α, IL-1β, and IL-8 levels, while others have shown high levels of those cytokines.(7,20-22) In addition, new opinions during recent years have claimed that cytokines may play a role in the pathogenesis and be responsible for many symptoms of FM.(5,8) Table 4 summarizes the relationship between certain cytokines and the FM symptoms.(5,22) It has been reported that cytokines such as TNF-α, IL-1, IL-6, and IL-8 contribute to the development of peripheral neuropathy, they are associated with HPA and sympathetic nervous system, and catecholamines ensure the release of these cytokines.(8,23)
|TNF-a||Stress, REM sleep, allodynia, fatigue, depression|
|IL-1b||Stress, fever, fatigue, sleep, myalgia|
|IL-2||Myalgia, cognitive dysfunction|
|IL-6||Stress, fatigue, hyperalgesia, depression, activates sympathetic nervous system|
|IL-8||Substance P stimulates production, sympathetic pain, REM sleep|
|TNF-a: Tumor necrosis factor-alpha; REM: Rapid eye movement; IL-1b: Interleukin-1 beta; IL-2: Interleukin-2; IL-6: Interleukin-6; IL-8: Interleukin-8; IL-10: Interleukin-10.|
The IL-8 causes hyperalgesia, activating the sympathetic nervous system by means of a mechanism independent from prostaglandins.(24,25) In addition, it has been shown that glial cell activation in chronic pain, such as FM, results in central sensitization and hyperalgesia.(24,25) Glial cell activation causes the release of cytokines such as TNF-α, IL-1β, and IL-8. There are several studies indicating that the level of IL-8 in FM is not different from that of healthy individuals,(9,26) while some others have found higher levels in FM patients.(7,21) Gur et al.(27) reported that IL-8 was related to pain severity in patients with FM. Kadetoff et al.(25) also found higher IL-8 levels in the cerebrospinal fluid of 15 patients with FM, compared to the control group, and concluded that IL-8 was responsible for hyperalgesia. The correlation between the FIQ and IL-8 has also been shown in a very recent study.(21) In our study, although the level of IL-8 in the fibromyalgia group was not significantly different compared to the control group, a significant correlation between the VAS scores and IL-8 levels of the patients was found suggesting that IL-8 can affect the pain severity. We consider that the correlation between the VAS and IL-8 supports that IL-8 may lead to hyperalgesia.
Furthermore, many endogenous and exogenous impacts of IL-1 such as weight loss, sleep regulation, regulation of the immune system and nervous system functions, neuronal transmission, epilepsy, and nerve cell death have been demonstrated.(28) IL-1 is produced by the liver and induces hyperalgesia with vagal stimuli. It also regulates the release of substance P, thereby, contributing to the development of fever.(28) Although it is considered that IL-1 contributes to symptoms such as somnolence, hyperalgesia, fatigue, myalgia, and depression in patients with FM,(22) many studies have shown that IL-1β levels are similar among patients with FM and healthy individuals.(20,22,27) In one report, IL-1 levels were lower in 64 patients with FM.(29) Accordingly, we detected no statistically significant difference between patients with FM and healthy controls in terms of the IL-1β levels, and therefore the IL-1β levels did not correlate with any parameters of disease severity.
Tumor necrosis factor-alpha is produced when the organism is exposed to any inflammatory or infectious stimuli. The major biological role of TNF-α is to defend the organism against bacterial, viral, or parasitic infections.(30) In addition, TNF-α synthesis occurs by means of stress, substance P release, rapid eye movement (REM) sleep, allodynia, norepinephrine, and epinephrine stimulation.(8) It has been proposed that TNF-α is responsible for hyperalgesia, myalgia, fatigue, depression, and REM sleep in FM patients.(8) In our study, there was no significant difference in the serum TNF-α levels between the patient and control groups. However, we found a statistically significant correlation between the VAS scores and serum TNF-α levels in the FM patients. This finding supports the hypothesis that the TNF-α levels can affect the severity of pain, thereby, resulting in hyperalgesia in patients with FM.
To the best of our knowledge, this is the first study investigating the correlation between Ox-LDL and FM. The former is an indicator of oxidative stress, which ensures correlation between inflammation and immune system.(14) It has pro-inflammatory effects and increases the release of inflammatory cytokines and cell adhesion, migration, proliferation, and apoptosis. Oxidized low-density lipoprotein occurs in many diseases due to oxidative stress, such as atherosclerosis, sepsis, and chronic obstructive pulmonary disease.(15,31) In recent years, several studies have been conducted examining the oxidative system in FM patients. These studies have suggested that oxidative stress contributes to the pathophysiology of the disease and have shown lower antioxidant activity in FM population.(2,10) Low antioxidant levels are unable to compete with the reactive oxygen species (ROS). This causes the accumulation of ROS inside the cells and then the lipid peroxidation and in turn, destruction of polyunsaturated fatty acids of the cell membrane, resulting in cell death.(2) In patients with FM, there is a potential connection between the inflammatory process and oxidative stress. In light of these data, we evaluated serum levels of Ox-LDL in the FM patients. We found no significant difference in the Ox-LDL levels between the FM patients and healthy controls. Interestingly, however, we found a positive correlation between the Ox-LDL levels and SSS scores of the FM patients. In the literature, there is no such correlation reported earlier, although there are several studies showing the correlation between lipid peroxidation and pain, depression, and FIQ scores.(32,33) Although we detected similar serum Ox-LDL levels in the FM patients and healthy controls, we cannot conclude that Ox-LDL certainly does not play a role in the etiopathogenesis of FM. Therefore, further, large- scale studies are still needed to investigate the levels of serum Ox-LDL in patients with FM.
The contradictory results of previous studies on the role of pro-inflammatory cytokines in the etiopathogenesis of FM might have resulted from different parameters used such as the inclusion criteria, presence of comorbidities, use of medications, symptom patterns and duration of FM, age, and BMI of the patients, and physical activity patterns. In the present study, we attempted to avoid the factors which might affect the levels of serum cytokines as far as possible, by excluding patients with comorbidities. We also avoided the potential role of obesity in inflammation since the mean BMI was very similar and normal in both groups. These are strengths of our study. However, the small sample size is the main limitation of our study, necessitating further large-scale studies.
In conclusion, our results do not support that the levels of cytokines (TNF-α, IL-Iβ, IL-8) and biomarker of the oxidative stress (Ox-LDL) are elevated in FM patients, although the results suggest that pain experienced by FM patients may be correlated with the levels of TNF-α, IL-8, and Ox-LDL. However, well-designed, large-scale studies are required to confirm these findings.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
This study was supported by Bulent Ecevit University Scientific Research Fund (Project Number: 2013- 93733444-01).
The authors would like to thank Dr. İshak Özel Tekin MD for his precious dedication and care in the studies of tumor necrosis factor-alpha-blocker and oxidized low- density lipoprotein and to Ça¤atay Büyükuysal, Ph.D. and Füruzan Köktürk, Ph.D. for their contributions in the statistical analyses of the data.
- Mease P. Fibromyalgia syndrome: review of clinical presentation, pathogenesis, outcome measures, and treatment. Rheumatol Suppl 2005;75:6-21.
- Pernambuco AP, Leite Schetino LP, Cota Carvalho LDS, Reis DD. Involvement of oxidative stress and nitric oxide in fibromyalgia. Fibrom Open Access 2016;1:1000105.
- Ang DC, Moore MN, Hilligoss J, Tabbey R.MCP-1 and IL-8 as pain biomarkers in fibromyalgia: a pilot study. Pain Med 2011;12:1154-61.
- Wallace DJ, Margolin K, Waller P.Fibromyalgia and interleukin-2 therapy for malignancy. Ann Intern Med 1988;108:909.
- Uçeyler N, Häuser W, Sommer C. Systematic review with meta-analysis: cytokines in fibromyalgia syndrome. BMC Musculoskelet Disord 2011;12:245.
- Staud R.Cytokine and immune system abnormalities in fibromyalgia and other central sensitivity syndromes. Curr Rheumatol Rev 2015;11:109-15.
- Bazzichi L, Rossi A, Massimetti G, Giannaccini G, Giuliano T, De Feo F, et al. Cytokine patterns in fibromyalgia and their correlation with clinical manifestations. Clin Exp Rheumatol 2007;25:225-30.
- Rodriguez-Pintó I, Agmon-Levin N, Howard A, Shoenfeld Y. Fibromyalgia and cytokines. Immunol Lett 2014;161:200-3.
- Xiao Y, Haynes WL, Michalek JE, Russell IJ. Elevated serum high-sensitivity C reactive protein levels in fibromyalgia syndrome patients correlate with body mass index, interleukin-6, interleukin-8, erythrocyte sedimentation rate. Rheumatol Int 2013;33:1259-64.
- Ranzolin A, Duarte AL, Bredemeier M, da Costa Neto CA, Ascoli BM, Wollenhaupt-Aguiar B, et al. Evaluation of cytokines, oxidative stress markers and brain-derived neurotrophic factor in patients with fibromyalgia - A controlled cross-sectional study. Cytokine 2016;84:25-8.
- Chung CP, Titova D, Oeser A, Randels M, Avalos I, Milne GL, et al. Oxidative stress in fibromyalgia and its relationship to symptoms. Clin Rheumatol 2009;28:435-8.
- Ozgocmen S Ozyurt H, Sogut S, Akyol O, Ardicoglu O, Yildizhan H. Antioxidant status, lipid peroxidation and nitric oxide in fibromyalgia: etiologic and therapeutic concerns. Rheumatol Int 2006;26:598-603.
- Tekin IO, Orem A, Shiri-Sverdlov R. Oxidized LDL in inflammation: from bench to bedside. Mediators Inflamm 2013;2013:762759.
- Greig FH, Kennedy S, Spickett CM. Physiological effects of oxidized phospholipids and their cellular signaling mechanisms in inflammation. Free Radic Biol Med 2012;52:266-80.
- Shen Y, Yang T, Guo S, Li X, Chen L, Wang T, et al. Increased serum ox-LDL levels correlated with lung function, inflammation, and oxidative stress in COPD. Mediators Inflamm 2013;2013:972347.
- Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res (Hoboken) 2010;62:600-10.
- Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 1990;33:160-72.
- Burckhardt CS, Clark SR, Bennett RM. The fibromyalgia impact questionnaire: development and validation. J Rheumatol 1991;18:728-33.
- Sarmer S, Ergin S, Yavuzer G. The validity and reliability of the Turkish version of the Fibromyalgia Impact Questionnaire. Rheumatol Int 2000;20:9-12.
- Wang H, Moser M, Schiltenwolf M, Buchner M. Circulating cytokine levels compared to pain in patients with fibromyalgia -- a prospective longitudinal study over 6 months. J Rheumatol 2008;35:1366-70.
- Mendieta D, De la Cruz-Aguilera DL, Barrera- Villalpando MI, Becerril-Villanueva E, Arreola R, Hernández-Ferreira E, et al. IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients. J Neuroimmunol 2016;290:22-5.
- Wallace DJ, Linker-Israeli M, Hallegua D, Silverman S, Silver D, Weisman MH.Cytokines play an aetiopathogenetic role in fibromyalgia: a hypothesis and pilot study. Rheumatology (Oxford) 2001;40:743-9.
- Malek H, Ebadzadeh MM, Safabakhsh R, Razavi A, Zaringhalam J. Dynamics of the HPA axis and inflammatory cytokines: Insights from mathematical modeling. Comput Biol Med 2015;67:1-12.
- Gur A, Karakoc M, Erdogan S, Nas K, Cevik R, Sarac AJ. Regional cerebral blood flow and cytokines in young females with fibromyalgia. Clin Exp Rheumatol 2002;20:753-60.
- Kadetoff D, Lampa J, Westman M, Andersson M, Kosek E. Evidence of central inflammation in fibromyalgia-increased cerebrospinal fluid interleukin-8 levels. J Neuroimmunol 2012;242:33-8.
- Uçeyler N, Valenza R, Stock M, Schedel R, Sprotte G, Sommer C. Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain. Arthritis Rheum 2006;54:2656-64.
- Gür A, Karakoç M, Nas K, Remzi, Cevik, Denli A, et al. Cytokines and depression in cases with fibromyalgia. J Rheumatol 2002;29:358-61.
- Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol 1998;16:457-99.
- Hernandez ME, Becerril E, Perez M, Leff P, Anton B, Estrada S, et al. Proinflammatory cytokine levels in fibromyalgia patients are independent of body mass index. BMC Res Notes 2010;3:156.
- Bradley JR.TNF-mediated inflammatory disease. J Pathol 2008;214:149-60.
- Jin W, Zhao Y, Yan W, Cao L, Zhang W, Wang M, et al. Elevated circulating interleukin-27 in patients with coronary artery disease is associated with dendritic cells, oxidized low-density lipoprotein, and severity of coronary artery stenosis. Mediators Inflamm 2012;2012:506283
- Cordero MD, Alcocer-Gómez E, Cano-García FJ, De Miguel M, Carrión AM, Navas P, et al. Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma.PLoS One 2011;6:26915.
- La Rubia M, Rus A, Molina F, Del Moral ML. Is fibromyalgia-related oxidative stress implicated in the decline of physical and mental health status? Clin Exp Rheumatol 2013;31:121-7.


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NetEnt Releases Much-Awaited Narcos Video Slot
May 24, 2019
Narcos, based on the hit TV series, is the new branded title from NetEnt, and it offers a variety of features like Walking Wilds, Drive-by, and Locked Up.
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domain: entertainment


It’s been a sensational weekend for GP3 in Sochi. For the first time since Austria drivers championship leading driver Bastian Paisler had to skip races, which would have allowed runner-up Benjamin Roeske to cut down Paislers lead to a minimum. But it went all wrong for Roeske.
Pole setter Constantin Grimminger. team mate of Roeske, won the start aswell as turn one, before forcing Roeske later into a spin. This plus another incident ruined Roeskes race and nearly all chances of winning the title in 2014. Later on, Grimminger dominated the race and won by over 6 seconds for the first time since October 2013. Still, he was found guilty by the Stewarts for crashing Roeske, giving him a warning and by that, a 10 place grid penalty for the first race in Abu Dhabi.
Podium finishers were originally Jenzer boys Sebastian Dahlmann on P2 and Marc Stwerka on P3, but Stwerka was later found been guilty on forcing Gallego off track, giving him a +10 seconds penalty, which moved up Status GP driver Victor Forner on P3.
Race 2 began with Roeske spinning in the formation lap, which caused him to lose his rear wing. Back in pits, he repaired the damage and started the race from the pits. At this Moment, he was also still in the hunt for the drivers title.
Grimminger made by far the best start, moving up seven places already into turn 2, being second behind Hilmer Motorsport’s Martin Jatzek. By that, the German showed his hunger for another win. But it went all wrong for him, as he later crashed into Forners back. Luckily enough Forner escaped the collision without any visible damage and continued leading the race. Only half a lap later Stwerka also crashed into Forner, which finally gave Forner the momentum to be alone into the lead. He won in front of his team mate Miguel Veneno, who collected his first podium. Martin Jatzek had a great opportunity to win the race, but was collected by Daniel Wilhelmi and finished 3rd.
Roeske collided already in Lap 5 with Miguel Veneno, which destroyed his race finally in a spectacular race. He was been found guilty, but not penalized.
It was obvious by that already that Paislers lead was unreachable and so is the old and new champion of the GP3 series. Congratulations!
While P1 and P2 are already decided in drivers championship, P3-5 are still in a close fight. At the moment, Grimminger leads this group by two points over Stwerka, who leads by just three points over Carlos Frau. We will see a tight race between these three in Abu Dhabi for sure!
Also, the team’s championship is yet undecided. Carlin does lead over Arden International by 26.5 points. We can be sure that both teams will fight for the title as hard as they can!
See you for a surely amazing race in Abu Dhabi.


Early this year, when it became clear that the Chevrolet Volt and Nissan Leaf had missed their 2011 sales targets, critics declared the electric-car revolution over. Yet at Detroit's annual North American International Auto Show in January, plug-in cars abounded. BMW displayed its forthcoming i3 electric city car, along with its i8 plug-in hybrid sports car. Acura unwrapped a hybrid concept version of the NSX supercar. Tesla Motors brought its all-electric Model S sedan. But the most important car on the show floor might have been one that, on the surface, seemed much less exciting: the new Ford Fusion, which will be available in gasoline, hybrid and plug-in hybrid versions.


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Throughout the Covid pandemic we have been here to support you with your emotional health and well-being. We are aware that some people continue to feel concerned about COVID-19 – please refer to our blog post entitled Managing Worries in Relation to COVID-19. We encourage you to reach out and contact us if you feel you need some extra support, and we encourage all our current clients to maintain their ongoing psychology appointments.
Whilst COVID restrictions eased on the 15th of December 2021, we have made the decision to continue to protect our community by maintaining our covid policy for the time-being. We will continue to require anyone entering the practice to wear a mask and sanitise hands upon entry.
In order to provide our clients and staff with a safe environment we are practising social distancing in the clinic. We ask clients to please stay at home if they are unwell or showing any symptoms that could spread illness (fever, coughing and/or runny nose). We are taking measures to ensure high standards of hygiene control in the practice, including more frequent cleaning of the office space. For anyone who can’t attend in person due to respiratory symptoms, please continue your appointments via videoconferencing or telephone if you feel up to it.
To obtain further relevant information about Covid in NSW, please see the government website:


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Your prompt today: hibernation.
It's been one of those days.
The grey, dark time of year,
Though not as long as it appears,
Is never welcome here.
Strong urges to go south,
To place sweet pastries in my mouth,
To stomp my feet and shout,
That is what winter brings,
Along with the deep blues it sings -
Such a miserable thing.
So I shall stay in bed,
With covers pulled up to my head,And 'till spring I'll play dead.


Goal Frenzy: Sensational Scoring in Today’s Soccer Showpiece
In recent years, soccer has witnessed a goal frenzy like never before. Today’s soccer showpiece, whether it’s the FIFA World Cup, UEFA Champions League, or domestic leagues like the English Premier League or La Liga, has become a spectacle of sensational scoring. Gone are the days when a single goal would be celebrated; now, fans are treated to a plethora of goals in every match.
One of the main reasons for this goal frenzy is the evolution of tactics and strategies employed by teams. Coaches have become more tactical and meticulous, focusing on attacking football rather than a conservative approach. Modern-day coaches prioritize their team’s offensive capabilities and encourage quick, free-flowing football that keeps fans on the edge of their seats.
The emergence of world-class players who possess exceptional technical abilities and creativity has also contributed to the rise in goal-scoring. The likes of Lionel Messi, Cristiano Ronaldo, Kylian Mbappe, and others have set new standards, not only in their respective leagues but also in international competitions. These players are capable of converting any half-chance into a goal and have revolutionized the game with their incredible scoring prowess.
Another factor that has fueled the goal frenzy is the advancements in sports science and player conditioning. Today’s players are fitter, faster, and stronger than ever before. The implementation of high-intensity training, sports science monitoring, and improved nutrition has allowed players to perform at their peak for longer durations, resulting in an increase in goals throughout the match.
Additionally, changes in the rules and regulations of the game have also contributed to the rise in goal-scoring. For instance, the introduction of Video Assistant Referee (VAR) has led to more penalties being awarded, providing an opportunity for additional goals. Moreover, stricter defending has resulted in an increased number of free-kicks and set-piece goals.
The modern soccer fan wants to be entertained, and goals are what make the sport exciting. The availability of instant replays, highlights packages, and social media platforms has intensified the demand for more goals and captivating performances. As a result, teams add extra emphasis on attacking plays to satisfy the fans’ appetite for goals.
Despite the goal frenzy, it is worth noting that defensive prowess has not taken a back seat. Teams are still aware of the importance of maintaining a solid defense and preventing the opposition from scoring. However, there has been a shift in focus, with teams balancing their defensive stability with an attacking mindset.
This sensational scoring not only adds excitement and entertainment value to the game but also pushes it to new heights. Fans are treated to breathtaking goals and memorable moments that will be forever etched in their minds. The goal frenzy has elevated soccer to a level where it is not just a sport, but an art form.
In conclusion, the goal frenzy witnessed in today’s soccer showpiece is the result of a combination of several factors. The evolution of tactics, the rise of exceptional players, advancements in sports science, changes in rules, and the desire to entertain fans have all contributed to this phenomenon. Soccer has become a high-scoring spectacle that captivates audiences worldwide and keeps them coming back for more.


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A package of immigration-related bills earned California Gov. Jerry Brown's signature Saturday, including a bill that prohibits local law enforcement agencies from detaining people for deportation if they are arrested for a minor crime and otherwise eligible to be released from custody.
AB4 by Assemblyman Tom Ammiano, D-San Francisco, creates a statewide standard for how local agencies comply with the federal Secure Communities program, which requires law enforcement to check the immigration status of those who are arrested and to hold for 48 hours anyone whom federal authorities wish to detain.
The law Brown signed allows state and local police and sheriff's departments to detain immigrants only if they have been arrested for or convicted of certain serious or violent felonies. People could also be held if they were convicted of a misdemeanor crime that carries a felony equivalent or if they are registered as sex offenders.
The governor vetoed a similar measure last year because it did not let officials detain those convicted of crimes such as child abuse and drug trafficking, exemptions that were removed from this year's version.
The California District Attorneys Association remained opposed to the legislation, however, expressing concern it “could result in the inappropriate and untimely release of potentially dangerous offenders” and “would frustrate local cooperation with federal officials who maintain exclusive province over the enforcement of immigration law.”
“It appears that this bill would permit a local policy to trump federal law, and it is not clear how such a provision would pass constitutional muster,” the association wrote before the bill cleared the Legislature.
The guidance spelling out when officers would comply with the federal deportation program was one of eight immigration-related measures Brown signed as he faces an Oct. 13 deadline for approving or vetoing legislation.
The governor also approved a bill allowing lawyers to be admitted to the California bar even if they are living in the U.S. illegally.
The package of bills also included a measure stating that someone who threatens to report an immigrant's illegal status to authorities could be charged with criminal extortion, and a related law subjecting employers who retaliate against workers on the basis of immigration to fines and the loss of their business licenses.
Also on Saturday, immigrants and supporters marched through Hollywood as part of an effort taking place across the nation pushing for immigration reform.
The event called "March of the Stars" lasted several hours Saturday and was one of more than 150 that are part of what organizers are billing as a "National Day for Dignity and Respect." The mobilization was a prelude to a rally and free concert Tuesday on the National Mall in Washington.
Immigration has been a rare area of bipartisan cooperation and confidence was boosted earlier in the year on a sweeping overhaul of the system and a path to citizenship for millions. But the crisis over Syria, and now the partial government shutdown, has diverted the attention of legislators in D.C.
More Southern California Stories:
- Drastic Weather Changes Coming
- Firefighting Plane Damaged in "Hard Landing"
- CSUN, UCLA Warn of On-Campus Crimes
- Cancer Patient Gets Wedding Wish at Hospital
- Driver Shoots Officer With Cop's Gun
- Wacky Machines: Ventura Kinetic Race
- Hundreds Mourn Teen Killed in Fiery Crash
- Teen in Deadly Crash Was "Always Smiling"


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Report: The most powerful thing you can do to ensure success is to build an infrastructure that creates digital advantage.
Download the latest report from Open Banking Expo and Equinix on the future of Banking as a Service, industry opinion and insight along with the analysis from the event survey conducted in 2020.
The report has been produced to explore these insights and summarises the Open Up 2020 Challenge which was run in partnership by Nesta Challenges and the Open Banking Implementation Entity.
The Global Open Banking Report 2020, brought to you by The Paypers, has been released! Please download your free, printable PDF copy
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Making banking accessible for everyone, anywhere. Download this whitepaper from Axway to see how they’re helping 60% of the worlds 25 largest banks harness digital.
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Fast forward and download Yapily’s recent whitepaper to learn how the market could soon come of age, as it explores further innovations into the wider Open Finance space.
Recently released Open Banking report from UK based Fintech, Bud looks at a move to an Open Finance world.
This report takes a deep dive into developing and defining a common and open standard for the sector using a community approach.
The Paypers has launched Open Banking Report 2019, which strives to offer the freshest and most robust insights into the global Open Banking landscape.
How will your company utilise the transactional account data that the Open Banking will make available? How will it apply meaning to that data?
This report delineates how key data-driven approaches enable firms to use digitization to improve customer-centricity, successfully service the SME sector, and deliver winning customer service with smart data, analytics and machine learning.
Industry report provided by Equinix looking at the trends currently shaping the global digital payments space.


Ohio man drowns in Oak Orchard River in Carlton
A 67-year-old Ohio man drowned in Oak Orchard River in Orleans County on Thursday.
Orleans County sheriff’s deputies were called about 7:15 p.m. after William E. Rowe of Cincinnati jumped into the river and disappeared in the hamlet of Kenyonville, part of the town of Carlton.
His body was recovered about 8:45 p.m. by the Carlton Fire Department, deputies said in a news release. Deputies said Rowe was in the area for a three-day Lake Ontario fishing charter.
About 7:15 p.m., Rowe approached a group of teenage girls who were jumping off the Kenyonville Road bridge into the river and asked whether he could jump too, deputies reported.
The teens didn’t object so he jumped off the bridge, surfaced briefly and then went under, deputies said. Rpwe did not resurface.
Also assisting at the scene were Albion and Lyndonville fire departments, New York State Police and the sheriff’s marine unit.


The people of Nigeria voice concern over corrupt politicians, the negative influence of Shell and the vagabonds in power.
July 04, 2012
Discontent with Shell is continuing to grow in Nigeria, making room for another wave of protests against the vagabonds in power.
Corruption scandals surrounding Shell seem to dominate the media, creating anger from the public. The corruption penetrates every sphere of Nigerian electoral politics, creating conditions that demonstrate to the Nigerian people that street protest is their best vehicle for fighting back.
Farouk Lawan led a Nigerian parliamentary committee that investigated fuel importers in January over accusations they received 1.1 trillion naira ($6.7 billion) in illegal payments.
Now, Lawan is under investigation himself, facing serious questioning from the police over allegations that he took a $620,000 bribe from a fuel importer and frequent donor to Nigeria’s ruling party.
His recent reversal of roles, from accuser to accused is just a small part of a larger web of allegations and political infighting that have surrounded President Goodluck Jonathan’s administration. The extremely corrupt administration has been “unable” to meet the pledge to end fuel subsidies, reorganize the oil industry and “clean up the financial markets”.
A few months ago, Occupy Nigeria erupted against fuel subsidies, inspiring thousands of young and exhausted Nigerian citizens to take their concerns to the streets. We don’t know when a movement of this scale will erupt again, but with the influence of Shell, conditions in Nigeria continue to get worse. And as activist/singer Nneka pointed out in a recent interview, the people will be back.


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A Messy, Beautiful Life by Sara Jade Alan
Publication Date: October 2, 2017
Publisher: Entangled Teen
Arc provided by publisher in exchange for an honest review.
Life is funny sometimes.
And not always the ha, ha kind. Like that one time where a hot guy tried to kiss me and I fell. Down. Hard. And then found out I had cancer.
I’m trying to be strong for my friends and my mom.
And I’m trying so hard to be “just friends” with that hot guy, even though he seems to want so much more. But I won’t do that to him. He’s been through this before with his family, and I’m not going to let him watch me die.
So, I tell myself: Smile Ellie. Be funny Ellie. Don’t cry Ellie, because once I start, I might not stop.
Who would have thought that a book about a girl with Cancer would be funny? Not me. When I read the description of the book I was intrigued and new I wanted to read this. I needed to know what happened to Ellie and the guy that she wants to be “just friends” with.
Ellie is a part of her improv group at school, and on a night they are invited to participate in a show at another school where she meets Jason, a member of the other school’s improv team. After the show Ellie and her friends are invited to a party at Jason’s house and the invite is reiterated when Ellie runs into Jason at the beach. It’s during this party that Ellie has an accident that lands her in the hospital where she finds out she has a rare form of cancer in her leg. The events that follow her diagnosis lead us through a great story of love, family and friendship and how people are drawn together in a crisis.
One of the things I liked most about this story was the relationships that Ellie had, with not only Jason, but with her friends and her step-brother. Even when Ellie tried to push them away they stayed and fought right beside her. They refused to let her go through any of it on her own, especially Jason.
All in all this was a great read, funny when it needed to be, and serious when it was supposed to be.
Sara Jade Alan wrote her first comedy sketch during second grade recess, then cast it, directed it, and made costumes out of garbage bags. Since then, she has performed in over a thousand improvised and scripted shows all over the country. When she lived in New York City with her college improv group, she worked as an assistant to a best-selling author of young adult novels featuring strong female heroes and was completely inspired by her books and the awesomeness of her teen fans. Spending a year on crutches, Sara turned to writing her own young adult stories and was hooked. Currently, she is one-half of the comedy duo, The Novelistas, who perform about writing and teach performance to writers. Hailing from a suburb of Chicago, Sara now lives in Colorado with her husband—who she met in that college improv group—and daughter, who they waited a bunch of years to make. She is a member of and guest instructor at Lighthouse Writers Workshop.
- A Messy, Beautiful Life Prize Pack, which includes A Messy, Beautiful Life tote bag, DVD of the anime rom-com Ranma 1/2, Disco ball keychain, Bag of Marshmallow Mateys cereal


How is the performance of Nissan Micra Active?
By: Hari on 9 july 2014
Nissan Micra Active is a very smooth drive to ride. The flawless 1198CC engine is mated with a buttery smooth 5-speed manual gear box which ensures a hassle free ride even in city traffic. The engine is also very much responsive which ensures that this cutie pie become a enthusiast's delight.
Sonal Gupta 2014-07-09
Although, Nissan Micra Active is the sibling of Micra and available in only a petrol engine of 1.2L, which scoops out a max power of 67.04bhp at 5000rpm along with a yielding torque output of 104Nm at 4000rpm. This engine is mated with a 5 speed manual transmission gearbox delivering torque to the front wheels. It can achieve the 100kmph speed mark in mere 12 to seconds. It offers a meaty mileage of 19.49kmpl on long revs while on short, it delivers 16-17kmpl.
Related Questions on Nissan Micra Active
Manuj Malviya 2017-07-281Answer
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Rajeev Purushotam 2016-11-021Answer
There is a provision for two reverse lights in Nissan Micra so why is it that there is only one provided in my car that I bought in July 2016? Also, why wasn’t this odd feature told to me when I was buying this car?
KG PRASAD 2016-08-031Answer
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More on Nissan Micra Active


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14 teams made the NFL playoffs in 2020 and many of those teams are expected to contend for the postseason again. But one of those teams has NFL insider Peter King less than impressed heading into the season.
In his latest Football Morning in America column, King revealed that he is “cool on” the Indianapolis Colts. He listed off a bunch of issues they have and potential issues they might face as the season progresses.
The biggest criticism King has of the Colts is their current vaccination status. He pointed out that their star players, quarterback Carson Wentz and linebacker Darius Leonard, are both unvaccinated.
King noted that Wentz has already missed time due to close contact with an infected person. So long as he remains unvaccinated, he will miss time every time that happens.
Teams I’m cool on: I want to like the COLTS, but their two most important players, Carson Wentz and Darius Leonard, aren’t vaccinated, and Wentz just missed five days because of a close contact with an infected person. It seems incredible that, after missing five days of work with his new team on the heels of missing significant time due to foot surgery, that Wentz won’t take the shot. (A vaxxed player who has been a close contact with an infected person doesn’t sit unless he tests positive. An unvaxxed player sits for five days, no exceptions.) “Trust me, I have weighed a lot of things,” Wentz said. “I know what is at stake. It is just where I am at and where I am at with my family.” Does Wentz really know what is at stake? And is it really worth passing on an overwhelmingly safe injection for whatever reason he won’t take it? But that’s America in 2021.
NFL players are inevitably going to miss big games due to COVID-19. We’ve already seen several big name players get scratched from Week 1 after testing positive or coming into contact with someone who has.
That will inevitable affect wins and losses, and could be the difference between a team making the playoffs and not.
The Indianapolis Colts made the playoffs at 11-5 last year and expect to make it again this year. But if King is right, they may find themselves to be a bigger obstacle than any particular team.