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Topex-CD Syrup sweetener may be a mixture medication used withinside the remedy of dry cough. It relieves aversion signs and symptoms inclusive of fluid nose, stuffy nose, throat irritation, sneezing, watery eyes and congestion or stuffiness. Topex-CD sweetener is fascinated with or with out meals during a dose and length as recommended via manner of means of the health professional. The dose you’re given can rely on your state of affairs and also the way you reply to the medication. you wish to carry taking this medication for thus long as your health practitioner recommends. If you stop remedy too early your signs and symptoms can also return and your state of affairs may also worsen. Let your tending crew acknowledge roughly all totally different medicines you’re taking as a number of may also affect, or be sick with this medication.
The utmost not unusualplace facet consequences are nausea, vomiting, constipation, lightheadedness, shortness of breath, and sweating. Most of these are transient and unremarkably solve with time. Contact your health professional instantly} just in case you’re in any respect concerned approximately any of those aspect consequences. This medication can also purpose giddiness and sleepiness, so do now now not force or do some issue that necessitate intellectual recognition until you perceive however this medication influences you. Avoid ingesting alcohol at the same time as taking this medication because it could create giddiness worse. ne’er guide self-medicinal drug or counsel your medication to another person. Keep it out of attain of children. it’s helpful to possess several fluids even as taking this medicative drug. Before taking it, you wish to tell your health professional once you have any urinary organ or liver sicknesses so as that your health practitioner will inflict a acceptable dose for you. Pregnant or breastfeeding girls have to be compelled to look for recommendation from their health professional prior taking this medication.
Uses Of Topex-Cd Sweetener
• Dry cough
Advantages Of Topex-Cd Sweetener
• In Dry cough
A dry cough may be a cough whereby no phlegm or mucous secretion is produced. it’s going to additionally purpose a tickling sensation or skin sensation withinside the throat and may be due to bloodless, flu, hypersensitivity or throat irritants. Topex-CD sweetener suppresses intense dry cough and offers you remedy from an fidgety throat. except this, it additionally reduces signs and symptoms of aversion like watery eyes, physiological reaction and fluid nose. beside taking Topex-CD sweetener, gargling with heat salt water and having ginger or honey permit you to manage dry cough.
Aspect Effects Of Topex-Cd Sweetener
Most aspect consequences do currently now not need any scientific interest and disappear as your frame adjusts to the medication. Consult your health professional within the event that they persist or just in case you’re involved roughly them
Common Aspect Effects Of Topex-CD Syrup
• Physiological Reaction
A Way To Use Topex-CD Syrup
Take this medication withinside the dose and length as recommended via manner of means of your health professional. Check the label for directions prior use. live it with a cup and take it via way of means of mouth. Shake nicely earlier than use. Topex-CD sweetener is fascinated with or with out meals, but it’ miles higher to require it at a tough and quick time. Topex Cd sweetener 100ml is to be had in syrup and pill form.Tablet form: Your health practitioner can counsel however oftentimes you’re taking Topex Cd sweetener 100ml completely} totally for your scientific situation. Do currently now not crush, chew, or ruin the pill.Syrup form: Shake the bottle nicely prior use. Check the label for directions and take Topex Cd sweetener 100ml on an empty belly as prescribed via manner of means of your health professional with the assist of a cup that’s equipped the pack.Topex Cd sweetener 100ml have to be compelled to now no longer be used till prescribed via way of means of a health practitioner. continually take Topex Cd sweetener 100ml exactly as your health practitioner tutored you. Your health practitioner can advocate you the way frequently to require Topex Cd sweetener 100ml on the concept of your scientific situation.
However Topex-CD Syrup Sweetener Works
Topex-CD sweetener may be a mixture of medicines: Chlor-Trimeton and antitussive, that relieves dry cough. Chlor-Trimeton is an antiallergic. It blocks the motion of a chemical traveler (histamine) which can additionally cause cough due to allergic reaction. Codeine is a cough suppressant. It suppresses cough via manner of means of lowering the hobby of cough middle withinside the mind.
Topex Cd sweetener 100ml is a mixture of drugs, namely: Chlorpheniramine and Codeine. Chlorpheniramine belongs to the magnificence of antihistamines (anti-allergic drugs) that works via manner of means of preventative the motion of histamine, a substance in command of inflicting aversions. It permits to supply remedy from allergic reaction signs and symptoms inclusive of sneezing, going for walks nose, watery eyes, itching, swelling, and congestion or stiffness. antitussive belongs to the magnificence of narcotic cough suppressants that block the μ-opioid receptor withinside the mind that produces cough, thereby lowering the urge to cough. Collectively, Topex Cd sweetener 100ml accustomed trot out cough involving a not unusualplace bloodless or higher respiration susceptible reactions.


CALGARY, Alta. - It's a blustery February morning in Northern Manitoba and you awake to find your brakes have seized up overnight. Assuming the culprit is moisture in the air lines, what do you do? If...
MAINTAIN IT: Air dryers should be checked each fall and their dessicant filter should be replaced annually when running in cold areas.
Photo provided by Bendix
NET RESULT: This picture shows what can happen when you use alcohol to thaw valves and seals. This plastic part was melted after a propane torch was used to thaw it out once alcohol stopped working.
CALGARY, Alta. – It’s a blustery February morning in Northern Manitoba and you awake to find your brakes have seized up overnight. Assuming the culprit is moisture in the air lines, what do you do? If you’re like many drivers, you curse the maintenance manager and then pour alcohol into the system to thaw out any ice that’s accumulated there.
But experts warn that’s a dangerous habit to get into, which could cause costly – not to mention dangerous – ABS failures.
The best way to avoid problems caused by alcohol is to ensure the need to use alcohol doesn’t arise in the first place.
Nearly all Canadian trucks are equipped with an air dryer, and proper maintenance of this key component can virtually eliminate all instances of frozen air lines.
“Many fleets assume that the air dryers on the tractors are working well,” says Ray Camball, fleet sales manager with Trailmobile Canada.
“If things go wrong on a cold day with a rush load, the driver does what he can to get the load moving and it may mean that some alcohol gets dumped into the red air line.”
In a pinch, a tablespoon or two will likely solve the problem and allow you to continue on your way, but Camball says drivers sometimes use too much alcohol which can make the situation far worse.
“The driver is cold and he has a litre container in his hand and more can be dumped in just to be sure,” says Camball.
“It may also get poured into the blue line which is not a good idea because it can sit on top of the ABS valve in a pool and cause the O-ring to stick. The trailer may get rolling, but the pool of liquid alcohol can wash off protective grease and after a few soaks with alcohol, the ABS valve can stick resulting in no service brakes and a $1,000 cost to replace the alcohol-damaged valve.”
Camball has seen his share of damaged valves, many of which are not covered under warranty. The disturbing trend has prompted him to check with various fleets to see how they are avoiding the problem.
TST Overland Express has addressed the issue by paying close attention to its trucks’ air dryers – particularly on trucks that operate in extreme weather.
“In order to reduce air system freeze-ups without the need for using alcohol, a good air dryer service program is crucial,” insists Geoff Eaves, fleet superintendent with TST.
Eaves found that trucks operating in areas with long, cold winters were more likely to encounter air dryer failures, and as a result, the company developed a customized maintenance program. Trucks operating in Quebec, for instance, have their air dryers serviced and replaced more often than trucks that operate primarily in warmer Ontario.
“This helps to reduce downtime and makes the equipment more reliable,” says Eaves.
“When you are running on remote roads in conditions well below 0 degrees C and a long distance from the nearest service location, you want to do your best to provide your drivers with reliable equipment. Air line freeze-ups are inconvenient in southern climates but can be a major problem in remote northern areas.”
Glenn Bauer, president of Ventures West Transport, knows all about operating in remote northern areas.
The Edmonton, Alta.-based fleet runs the ice roads in the Northwest Territories each winter – an environment that can push air dryers to the limit.
“The biggest thing for us is preventive maintenance,” says Bauer. “Before the units go on the winter roads, everything is checked over and the air tanks are drained and cleaned.”
When his drivers encounter frozen brake lines, they are advised to use small amounts of a specially lubricated brake line antifreeze, which is less likely to remove the protective coatings from valves and seals than straight alcohol.
Operating in the far north requires extra measures to avoid freezing as well. Drivers try not to shut the units down for long periods of time (which can allow condensation to form) and they never dynamite the brakes.
The air dryer is maintained every fall and the desiccant cartridge is replaced annually.
“By following our preventive maintenance schedule, we’ve had next to no problems at all in winter road operation,” Bauer says.
Bill Fornof, senior staff engineer with Bendix Commercial Vehicle Systems, says replacing the air dryer’s desiccant cartridge each fall is a good idea, as contaminants can accumulate there. (A new cartridge costs about $50). He also said it’s important to test the air dryer’s heater by using a volt meter to measure the resistance across the heater.
“When you measure the resistance across the heater, there should be virtually nothing,” says Fornof. “If you’re getting a break in that line showing very high resistance, you know the heater’s not functioning properly.”
TST Overland’s Eaves takes this one step further, noting the thermostat for the heater should also be checked and it can only be tested in a cold environment, not inside a warm shop.
Fornof also suggests fleets and O/Os examine the air brake system to ensure there are no leaks which could cause additional strain on the compressor.
Trailer air dryers are now available and are recommended for fleets that find moisture is accumulating in their trailer brake systems (most likely through the gladhands). While trailer air dryers aren’t yet commonplace, Bendix officials say fleets in Northern Canada have been among the first to embrace the technology.
If alcohol is used too frequently, the long-term damage can be severe. Camball points out valve O-rings can stick to the cylinder walls after the alcohol acts as a type of glue.
“Liquid alcohol can free up the symptoms temporarily, but the valve will keep sticking more often until it totally fails,” he warns. “To ensure safe long valve life, clean, dry air is the best bet rather than having O-rings bathing in liquid alcohol.”
Bendix officials are quick to agree.
“Alcohol removes lubrication from the valves, shortens life of the components and in its purest form, it’s highly combustible,” says Chuck Eberling, principle engineer, Bendix Vehicle Systems Group.


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Kermani NZ, None , Song WJ, Badi Y, Versi A, Guo Y, Sun K, Bhavsar P, Howarth P, Dahlen SE, Sterk PJ, Djukanovic R, Adcock IM, Chung KF
Respir Res 22 (1) 101876 [2021-01-07; online 2021-01-07]
Bats are reservoirs for a large number of viruses which have potential to cause major human disease outbreaks, including the current coronavirus disease 2019 (COVID-19) pandemic. Major efforts are underway to understand bat immune response to viruses, whereas much less is known about their immune responses to bacteria. In this study, MR1-restricted T (MR1T) cells were detected through the use of MR1 tetramers in circulation and tissues of Pteropus alecto (Pa) bats. Pa MR1T cells exhibited weak responses to MR1-presented microbial metabolites at resting state. However, following priming with MR1-presented agonist they proliferated, upregulated critical transcription factors and cytolytic proteins, and gained transient expression of Th1/17-related cytokines and antibacterial cytotoxicity. Collectively, these findings show that the Pa bat immune system encompasses an abundant and functionally conserved population of MR1T cells with mucosal-associated invariant T-like characteristics, suggesting that MR1 and MR1T cells also play a significant role in bat immune defense.
NA: Available on request

domain: medical


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07 Aug 2019 18:20pm
SWAKOPMUND, 07 AUG (NAMPA) The story of a young transgender woman who survived human trafficking moved the Swakopmund community as she shared her story here on Wednesday.
Thirty-six-year-old Emma Naoses* told of her human trafficking ordeal during the commemoration of the belated World Day against Trafficking in Persons (TIP) in the Erongo Region, relating she was only 17-years-old when she was trafficked to Angola by a man she thought was her boyfriend.
The incident occurred 19 years ago, when the 75-year-old perpetrator lured Naoses to a party, where she said he would drug her heavily, in order to send her off to the neighbouring country.
I was trafficked and left in Luanda, without food, money or clothes for two years, while I was forced to engage in sexual acts against my will with people I did not know.
The man, who swore to love and care for me, sold me off to these people and told me I was his money-making machine and was therefore not leaving that situation, Naoses narrated.
Prior to the incident, Naoses was alone and vulnerable, after she was abandoned by her biological mother, sexually abused by her biological father and neglected by the rest of her family because of her sexuality and gender orientation.
At the age of 12, I made a conscious decision to get involved in prostitution in order to survive. It was during this period that I met this man, who under the pretence of kindness and love, saw my vulnerability and took advantage of me.
She said although she endured the most trauma during this heinous crime, she is a survivor and not a victim as it would be described.
Naoses is only one of the many casualties of the multi-billion dollar trafficking business across the world.
According to a 2018 report of the United Nations, a growing number of girls are being reported as victims of human trafficking, accounting for 23 per cent of all recorded cases.
Boys account for seven per cent of reported trafficking cases, down from eight per cent in 2014, and up from three per cent in 2004.
The report adds that 70 per cent of the cases are of adults over the age of 18 years.
The World Day Against Trafficking in Persons is an annual event commemorated on 30 July.
*Not her real name

domain: news


Clue is correct, at least for Iowa. Unless Corey can find something to override this law [emphasis mine]:
2 (a). A “steady circular red” light means vehicular traffic shall stop. Vehicular traffic shall remain standing until a signal to proceed is shown or vehicular traffic, unless prohibited by a sign, may cautiously enter the intersection to make a right turn from the right lane of traffic or a left turn from a one-way street to a one-way street from the left lane of traffic on a one-way street onto the leftmost lane of traffic on a one-way street. Turns made under this paragraph shall be made in a manner that does not interfere with other vehicular or pedestrian traffic lawfully using the intersection. Pedestrian traffic facing a steady circular red light shall not enter the roadway unless the pedestrian can safely cross the roadway without interfering with any vehicular traffic.


They know that if air strikes on their nuclear facilities come only from Israel, then they may be able to absorb some of the attacks and be able to retaliate across the Middle East.
A joint attack by Israel and the USA would pose them a far greater challenge.
Tehran knows that compared to the United States Air Force, the Israeli Air Force (IAF) could not sustain a massive attack and so would be expected to concentrate on six key areas.
These are the uranium enrichment plants at Fordo/Qom and Natanz, the uranium conversion plant at Isfahan, the heavy water plant at Arak, the nuclear reactor at Bushehr and Parchin military base.
There would be other targets, especially Iran's air defence systems, but nowhere near on the scale that the Americans could achieve.
Iran has already made some known contingency plans to defend its facilities and is likely to have undertaken other measures which remain secret.
They have moved thousands of centrifuges deep inside a mountain at Fordo, near the city of Qom. They know the Israelis have some bunker busting bombs, but far fewer than the Americans. The facilities at Natanz are also underground albeit less well protected.
Anti-aircraft systems have been concentrated on defending the other targets and Iran is hoping its radar system will give it advance notice of an attack and that its air force can shoot down Israeli jets.
Given its inferior jets, and less well trained pilots, that will be very difficult for Iran.
It does have Russian built MiG-29s and a few US built F-14 Tomcats, but neither are latest generation models. Iran is more likely to inflict damage through its anti-aircraft ground defences, and then retaliation.
Iran's core defence system is based around its Russian SA-5 surface to air missiles which can reach high altitude. For lower targets it has Tor-M1/SA-15 Gauntlet missiles, many of which are deployed on mobile systems. It also operates an old US designed Hawk surface to air missile system.
The Iranians would attempt, probably unsuccessfully, to jam the Israeli communication system, shoot down as many jets as possible, and then counter attack using asymmetric warfare and long range ballistic missiles.
Tehran has a long reach. It could activate its allies Hizbollah and Islamic Jihad, to fire missiles into Israel from Lebanon and Gaza. The Revolutionary Guard Quds Force is thought to have numerous sleeper cells around the world, especially in Latin America and Europe which might hit Jewish and Israeli targets.
If it wants to hit American interests, it can use all the above, and mobilize pro-Iranian forces in Afghanistan and Iraq. It might also target some of the Gulf countries including Saudi Arabia if the IAF flies over the country and the Saudi air force does not react.
The Iranian ballistic missile threat is formidable and its arsenal the largest in the Middle East. It has weapons with range extending from 150km (93 miles) up to 2,000km (1,243 miles), putting not only the Gulf countries but also Israel within its reach.
The Israelis fear that Iranian retaliation could include fitting ballistic warheads with chemical and or biological weapons for use against population centres. Any Iranian long range missiles are expected to target cities.
Another way Iran could retaliate would be an attempt to block the Strait of Hormuz in the Gulf through which passes 20% of all the world's oil.
The US Navy and others would go to war to keep it open, but despite having vastly superior navies, they might be vulnerable to the expected Iranian tactic of 'swarming' big ships with hundreds of small fast boats loaded with explosives.
The Iranian response to an Israeli attack is very unlikely to be contained to hitting Israel, if the bombs start falling, the region will be in uncharted territory.


Our innovative MRA units are produced by combining high-volume PCB fabrication techniques with advanced manufacturing technologies featuring monolithically integrated thin film processing and smart materials solutions. We are manufacturing the next generation microwave and millimeter-wave MRA devices and systems at the very boundary of mm-scale conventional production and micro/nano-scale future fabrication technologies.
What has i5 invented? i5 has invented an MRA technology of which working principle was inspired from that of chameleon. A parasitic surface of which geometry can dynamically be changed which is place din the near field of a driven antenna, enables changing antenna properties (frequency, polarization, radiation pattern) in response to the changes in the wireless channel. Click here for more details.


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|Academic History:||Ph.D., Texas A&M University (Agronomy) 1977
M.S., University of Arizona (Agronomy) 1974
B.S.A., University of Arizona (Agronomy) 1973
|Area of Expertise:||Turf Management|
|Office Location:||4115A Miller Plant Sciences Building|
|Shipping Address:||3111 Miller Plant Sciences Building
The University of Georgia
Athens, GA 30602-7272
|Additional Web site:||Keith J. Karnok|
Research, Teaching, and Extension Work
Dr. Keith Karnok is the author of more than 250 publications related to turfgrass science. Dr. Karnok began his teaching and research career at Ohio State University where he taught both introductory and advanced courses in turfgrass management. In 1983, he joined the faculty in the Department of Crop and Soil Sciences at he University of Georgia. Currently, he teaches four courses in turfgrass management and advises both undergraduate and graduate students specializing in turfgrass science. Dr. Karnok also advises the UGA Turf Club in addition to his on-campus teaching. Dr. Karnok serves as an instructor and coordinator of two distance-education programs administered by the University of Georgia. The most recent, which is recognized by the Golf Course Superintendents Association of America as a one-year certificate program, consists of ten college credit courses. Prior to the development of the college credit program, Dr. Karnok, in cooperation with the Professional Lawn Care Association of America, developed a continuing education (CEU) correspondence turfgrass management program. This basic course in turfgrass management has more than 3,500 students enrolled from all 50 states and 30 countries.
Dr. Karnok has more than 30 years of experience with both cool and warm season turfgrasses. His research interests include those factors affecting turfgrass root growth, the cause and control of localized dry spots caused by water-repellent soils and the understanding and use of turfgrass biostimulants. Dr. Karnok is a member of the International Turfgrass Society, Crop Science Society of America (CSSA), American Society of Agronomy (ASA), American Association for the Advancement of Science (AAAS) and the National Association of Colleges and Teachers of Agriculture (NACTA). He is also a member of the Golf Course Superintendents Association of America, Professional Lawn Care Association of America and the Sports Turf Managers Association. Dr. Karnok has chaired or served on numerous committees associated with these organizations. He served as editor of the scientific journal Crop Science, one of the most respected scientific journals in agriculture. Dr. Karnok is the recipient of many awards including the status of "Fellow" in CSSA, ASA, AAAS and NACTA. The designation of "Fellow" is the highest honor bestowed by a scientific society. He has also received the "Fred V. Grau Turfgrass Science Award" from the Crop Science Society of America in recognition of significant career contributions in turfgrass science. Finally, he has received 20 honors and awards for teaching excellence, including the "Josiah Meigs Award for Excellence in Teaching,"which is the University of Georgia's highest teaching honor."

domain: agronomy


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In the pursuit of justice and ethical treatment within mental health institutions, the case of Dawn Dziuba has caught the attention of individuals and organizations alike. Dawn Dziuba is currently a patient in the Forensic Treatment Center South in St. Louis, Missouri, and has been an inpatient since 2014. Dawn alleges that she is being subjected to retaliation for submitting complaints on behalf of herself and fellow patients who believe they have experienced unjust, inhumane, or illegal practices. Members from ISPS-US, led by the Advocacy Committee, have been closely monitoring Dawn's situation and actively supporting efforts to address the concerning circumstances she faces within the Missouri mental health system.
This swell of cross-organizational support has led Missouri State Representative Sarah Unsicker to write a letter, dated August 1st, to the Director of the Missouri Department of Mental Health regarding Dawn Dziuba's case, calling for an investigation. In a compelling letter, Representative Unsicker expressed her concern for Dawn's well-being, echoing the worries raised by MindFreedom International and the wider community. Representative Unsicker, an Attorney, also points out numerous legal irregularities in Dawn's case.
As Dawn's story continues to unfold, it serves as a reminder that collective action and advocacy are crucial to upholding justice, ethics, and the rights of every individual.
Letter from Rep. Sarah Unsicker to Missouri Department of Mental Health


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Federal Circuit No. 2013-1674
When an applicant takes it upon himself to obtain a patent by intentionally duping the Examiner as to material issues, the applicant's conduct is inequitable and will result in a finding of unenforceability. This is what the Federal Circuit found in upholding the District Court's decision in Apotex.
The technology of the patent on appeal, U.S. Patent No. 6,767,556 (“the ‘556 patent”) is a pharmaceutical composition comprising moexipril magnesium. The '556 patent is owned by Apotex, Inc. Dr. Bernard Charles Sherman, is the founder and chairman of Apotex, and is the sole inventor of the '556 patent. Dr. Sherman also wrote the application for the '556 patent.
The '556 patent is generally directed to a process for manufacturing moexipril tablets. Moexipril is an angiotensin-coverting-enzyme (ACE) inhibitor used to treat hypertension. Stability of moexipril is improved by preparing moexipril magnesium by reacting moexipril or its acid salt with an alkaline magnesium compound. The process claimed in the '556 patent is recited in the only independent claim, claim 1:
Claim 1. A process of making a solid pharmaceutical composition comprising moexipril magnesium, said process comprising the step of reacting moexipril or an acid addition salt thereof with an alkaline magnesium compound in a controlled manner in the presence of a sufficient amount of solvent for a predetermined amount of time so as to convert greater than 80% of the moexipril or moexipril acid addition salt to moexipril magnesium.
In the preferred embodiment of the '556 patent, moexipril hydroxide is reacted with magnesium hydroxide or the magnesium salt of a weak acid (e.g., magnesium carbonate) to obtain moexipril magnesium. '556 patent, col. 2, l. 66 to col. 4, l. 5. The process used is "wet granulation," which has been known in the pharmaceutical industry since the 1980s.
During prosecution of the '556 patent, the claims were rejected over (1) U.S. Patent No. 4,743,450 ("the '450 patent"), which discloses an ACE inhibitor and magnesium carbonate as an alkaline stabilizer, (2) UNIVASC® and UNIRETIC®, which are made using the process described in U.S. Patent No. 4,743,450 to Warner-Lambert ("the 450 patent;" which is listed in the Orange Book for both products), and (3) an NPL reference ("the Gu article;" Gu et al., Drug-Excipient Incompatibility Studies of the Dipeptide Angiotensin-Converting Enzyme Inhibitor, Moexipril Hydrocholride: Dry Powder vs. Wet Granulation, 7. Pharm. Res. 379 (1990)), which describes the chemistry involved in stabilizing moexipril, including a wet process for converting moexipril to moexipril magnesium. In addition, the background section of '556 patent includes a discussion of all of the above prior art. In this discussion, Dr. Sherman characterized each of the prior art as including a combination of two individual compounds, i.e., Dr. Sherman describes the compositions of each of the prior art as including unreacted moexipril and a stabilizer. In fact, during prosecution, at the direction of Dr. Sherman, counsel submitted the product monographs for UNIVASC® and characterized the same as including a moexipril composition that contains magnesium oxide that is "unreacted but combined and [functions] as a stabilizer." Counsel also characterized the Gu article as teaching that the components of the moexipril composition disclosed therein as containing moeixipril hydrochloride and an alkaline stabilizing agent that are "merely combined and any reaction is insignificant to the desired end result," again at the direction of Dr. Sherman. An expert Declaration by Dr. Michael Lipp was also submitted, in which Dr. Lipp reinforced the representations regarding the prior art that were included in the application as well as counsel's arguments submitted during prosecution. In a subsequent Interview, the Examiner agreed to allow the application when Dr. Sherman's counsel agreed to amend claim 1 to recite that "greater than 80%" of the moexipril or moexipril acid salt is converted to moexipril magnesium. The Examiner's basis for allowing the application was that "the prior art teaches that only a portion of the drug (if any) may be converted to the alkaline salt and that the stable product results entirely or primarily not from conversion to alkaline salts, but from stabilization of the moexipril hydrochloride by the presence of the alkaline stabilizing compound in the final product." It should be noted that the Examiner's reasons above were in line with Dr. Sherman's characterization of the prior art.
Upon issuance of the '556 patent Apotex filed suit in the Southern District of Florida alleging infringement of the '556 patent by UCB (licensee of the '450 patent from Warner Lambert) based on their manufacture of UNIVASC® and UNIRETIC®, and generic versions of the same. The District Court found the '556 patent to be unenforceable based on inequitable conduct. On appeal, the Federal Circuit analyzed the Dr. Sherman's actions for both materiality and intent.
The Federal Circuit found clear and convincing evidence that Dr. Sherman engaged in material misconduct. Primarily, the court found that Dr. Sherman directed the prosecution of the '556 patent application, both through his counsel and through Dr. Lipp. Dr. Sherman directly instructed his counsel to continue to submit arguments that mischaracterized the prior art references, and also failed to inform Dr. Lipp of the true facts surrounding the composition of UNIVASC®. In fact, at the District Court, Dr. Lipp testified that he was specifically asked to limit his discussions only to the documents provided by Apotex, which did not include any information on experiments conducted by Apotex on UNIVASC®. The UNIVASC® product was tested by Apotex, and the results showed that the final product "mainly" contained moexipril magnesium. At no time during prosecution of the '556 patent application was this data disclosed to the Patent Office. In contrast, Dr. Sherman continued to mischaracterize UNIVASC® as containing unreacted moexipril and an alkaline stabilizing agent. Moreover, as part of its infringement case, Apotex conducted NMR tests to show that UNIVASC® contains more than 80% moexipril magnesium, which contradicted all of Dr. Sherman's previous assertions about this product. The Federal Court also determined that "but-for" Dr. Sherman's mischaracterization of the prior art, the Examiner would not have allowed the '556 patent to issue. The Federal Circuit clarified that an applicant for a patent is entitled to advocating, in good faith, a reasonable interpretation of the teachings of the prior art. SeeRothman v. Target Corp., 556 F.3d 1310, 1328-29 (Fed. Cir. 2009). However, Dr. Sherman "affirmatively and knowingly misrepresented material facts regarding prior art," and the Federal Circuit found "particularly significant and inexcusable that Dr. Sherman arranged for the preparation and submission of an expert declaration containing false statements instrumental to issuance of the patent."
With regard to Dr. Sherman's intent, the Federal Circuit found clear and convincing evidence to establish Dr. Sherman's intent to deceive the Patent Office, based on his blatant mischaracterization of prior art, submission of an expert declaration to bolster such mischaracterizations, and withholding of prior art. In addition, Dr. Sherman admitted that he never performed any of the experiments described in the '556 patent, but nonetheless, drafted the examples in the specification in past tense. The Federal Circuit agreed with the District Court that "Dr. Sherman's conduct evidences a pattern of lack of candor… deceptive intent is the single most reasonable inference that can be drawn from the evidence."
The Federal Circuit affirmed the decision of the District Court of the Southern District of Florida, finding that the district court did not abuse its discretion in holding the '556 patent to be unenforceable due to inequitable conduct.

domain: chemistry


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Women Activists in the Western Balkans and Turkey
The 2018 theme for International Women’s Day is “Time is Now: Rural and urban activists transforming women’s lives.”
On the occasion of this global celebration of women, the EU-UN Women regional programme "Implementing Norms, Changing Minds," which partners with 48 civil society organizations in the Western Balkans and Turkey, has created an interactive map showcasing some of the brave women working to end discrimination and violence in the region.
The map celebrates the work and voices of the activists who are working relentlessly to claim women’s rights and help them realize their full potential.
Click on each country to meet our activists!

domain: sociology


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Time Zones and County Information for Cities in Illinois
For information about latitude and longitude co-ordinates for cities and towns in Illinois, please visit the Illinois latitude and longitude page.
Map of Counties in Illinois
|A map of counties in Illinois. You can also download this map in PDF format.|
Time Zone and Counties for Cities in Illinois
Due to the number of cities in Illinois, we have reduced the cities shown to only those that have a population of 5,000 or more.
Click a heading to sort the table.

domain: geography


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How to Make a Butterfly Origami
Origami, the ancient Japanese art of paper folding, has captured the hearts and minds of arts and crafts enthusiasts around the world. With its intricate and delicate designs, origami is a beautiful way to create impressive decorations or gifts. One of the most popular origami creations is the butterfly. In this article, we will explore the step-by-step process of creating an origami butterfly.
To begin, gather your materials:
1. A square piece of origami paper (15 cm x 15 cm): Choose a colorful pattern or color that represents the butterfly you want to create.
2. A flat surface: A table or desk works well for folding.
Now that you have your materials ready, let’s get started with folding your own butterfly origami:
Step 1: Preparing the Paper
Place your square piece of paper on the flat surface with the colored side facing down. Fold it in half diagonally so that you create a triangle. Open it back up, then fold it diagonally in half again along the other diagonal. You should now have an X-shaped crease pattern.
Step 2: Creating a Rectangle
With your fingers along both diagonal crease lines close to where they intersect, bring them together so that four smaller triangles are created by the folds. Press down on these new folds to create a rectangle shape.
Step 3: Folding the Wings
Take one side of your rectangle and fold it back towards itself to meet at approximately halfway between the edge and middle line of your rectangle. Repeat this for the other side as well.
Step 4: Creating Triangular Wings
Take one of the folded edges from Step 3 and fold it down so that it forms a triangle where one side is parallel to the bottom edge of your rectangle. Repeat for the other folded edge.
Step 5: Trimming One Triangle
Unfold both triangles from Step 4 and take the edge of one of them. Fold it up once more, this time going beyond the centerline to create an offset triangle. Press firmly along this new fold.
Step 6: Unfolding the Butterfly
Carefully open up the butterfly along its central crease line. Using your fingers or a pen, gently press down on the center to create a crease running across horizontally.
Step 7: Adding Some Curves
To give your butterfly more life-like wings, gently curl the upper sections by using your fingers to shape them into subtle arcs.
Your butterfly origami is now complete! Admire your handiwork and share this beautiful creation with friends or family. Once you’ve mastered the folding process, experiment with different paper styles or sizes to create a diverse collection of origami butterflies. Happy folding!

domain: design


President Francois Hollande led the public event at Place de la Republique in memory of 17 people killed in the terror attacks last January.
He laid a wreath at the square where a 10 metre-high oak tree was planted and a one-minute silence held.
French rock giant Johnny Hallyday performed A Sunday In January – recalling a unity march of 1.6 million people in Paris following the attacks.
It was followed by songs from the French army choir and a reading from 19th century French poet and author Victor Hugo.
The reading struck a note of defiance calling Paris the "capital of civilisation" and said if Paris is attacked, civilisation is attacked.
The square has become a rallying point for the Je Suis Charlie movement and after the 13 November Paris attacks, which killed 130 people.
Sylvie Bermann, French Ambassador to the UK, told Sky News France had to respond to the "act of war" with strikes in Syria and fresh security and surveillance measures in France.
She said the country is "ready to fight in defiance against terrorism", adding that the "first priority is the security of our citizens".
French journalist Nabila Ramdani told Sky News: "Today is a chance for those connected with the attacks to show their unity to the world."
But she added that Paris had suffered because some still feared going out and "it is not as buzzing as it used to be".
Events have been taking place all week to mark the anniversary of the attacks on the satirical magazine and a Jewish supermarket.
Two Muslim extremists carried out the killings in revenge for publication in the magazine of cartoons depicting the Prophet Mohammed.


text:
Hodgdon man charged in connection with motorcycle theft
HODGDON, Maine — Aroostook County sheriff’s deputies arrested a Hodgdon man Dec. 12, following an investigation into a stolen motorcycle. The sheriff’s office did not release the details about the arrest until Jan. 15.
Deputies charged Michael Malone, 52, with receiving stolen property and criminal simulation. He is due in Houlton Unified Court in March to answer to the charges. According to Maine statutes, criminal simulation is when a “person alters, removes or obscures the manufacturer’s serial number or any other distinguishing identification number, mark or symbol” on a vehicle or machine.
Deputy Sheriff Richard York received an anonymous tip in early December about the possibility of a stolen motorcycle being stored at a residence in Hodgdon, according to Sheriff Shawn Gillen. York investigated and found a Harley Davidson Sportster that had the vehicle’s identification numbers and engine numbers removed.
The deputy seized the motorcycle and arranged for Detective Chad Foley of the Bureau of Motor Vehicles-Enforcement to inspect the motorcycle for identification.
“Upon further examination, Det. Foley, working with Special Agent Heidi Jordan of the National Insurance Crime Bureau, was able to identify the motorcycle as a 2008 HD Sportster XL1200 which had been reported stolen to the sheriff’s office in March of 2017 in Smyrna,” Gillen said.
The incident is still being investigated, the sheriff said.
Anyone with information on any criminal or illicit activity, may report it to Crime Stoppers at 1-800-638-TIPS(8477).They also can text information to Crime Stoppers at 538-TIPS(8477).

domain: law


US Intelligence Agencies Suspect Russia of Hacking Into Republican Party Servers
US intelligence agencies suspect that the Russian government was involved in the hacking of the Republican National Committee's (RNC) computer systems without further publication of the stolen data, The New York Times reported, citing sources.
MOSCOW (Sputnik) – Republican officials have repeatedly said that only individual accounts had been attacked, while their networks had not been compromised.
"We now have high confidence that they hacked the D.N.C. and the R.N.C., and conspicuously released no documents," and administration official said, as quoted by The New York Times newspaper.
The attack on Republican computer systems took place in spring, and the same hackers, who had attacked Democratic National Committee (DNC) servers, were behind it, the publication reported.
On Friday, US media reported that the Central Intelligence Agency (CIA) allegedly concluded in a "secret" assessment that Russia meddled in the November elections.
US intelligence and Homeland Security Department said in October they were confident the Russian government was behind the leak of emails from DNC servers, which exposed the party's attempts to undercut Hillary Clinton's rival Bernie Sanders in the race for nomination. Moscow has denied the allegations, with President Vladimir Putin saying that stories about Russian hackers and spies were attempts to distract US voters' attention from internal issues.
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text:
KUALA LUMPUR, Jan 16 – The flood situation in Sabah has improved while the number of evacuees in Perak, Kelantan and Pahang still placed at the relief centres have decreased this morning from last night. In SABAH, Pitas district officer Buduban Oti Majalau said all 38 flood victims from 10 families at the Dewan Kusilad relief centre in Pitas were allowed to return to their homes.
In PERAK, the number of flood victims recorded a drop to 1,219 from 335 families compared to 1,366 individuals from 380 families last night. Perak National Security Council (MKN) spokesman said the number of flood victims in Perak Tengah were 1,012, Hilir Perak (173) and Hulu Perak (34).
In KELANTAN, the number of evacuees have decreased to 545 in 13 relief centres from 908 last night. Kelantan Social Welfare Department spokesman said there were 515 evacuees from 111 families in 12 relief centres in Kuala Krai while in Machang, the number remained at 30 from eight families in one relief centre. In PAHANG, a spokesman from the state police headquarters flood operations room said the number had dropped slightly to 337 flood victims from 369 last night.


text:
Genre: Western , Drama
About: The moving picture Northern Patrol was first seen in the cinemas in 1953. Categorized as western and drama. will take you a total of minutes of watch time. 123Movies provied links and subtitles where you can watch it in HD for free.
Plot: This entry in the series featuring RCMP Rod Webb and his wonder dog, Chinook, has a larger cast than usual, popping in and out of about four different plot lines, which leads Chinook with less to do than usual, which makes it a better than usual entry. Corporal Webb (Kirby Grant) finds a man who seems to have hung himself after writing a suicide note. Webb notes this happened while the suicider was in the midst of cooking himself a meal, and concludes that all is not right in this part of Canada. Chinook agrees with him. Marion Carr, Claudia Drake and Gloria Talbott are on hand as (mighty nice) visual distractions. Read More

domain: artistic


Freshmeat page: http://freshmeat.net/projects/cml2+os
The goal of the Embedded Debian Project is to make Debian GNU/Linux a natural choice for embedded Linux. The Embedded Debian Project has produced extensions to Debian binutils/gcc/g++ packages to support cross development. These extensions are currently being merged into woody. Another product of the project is CML2+OS, a system for the configuration and generation of both a Linux kernel and an operating system (i.e. root filesystem). CML2+OS is being designed to assist embedded Linux developers in configuring and generating small (1 to 10Mb) Linux target systems.
This project has the following developers:
Keep up with the latest Advogato features by reading the Advogato status blog.


text:
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/5000.
RelevanceHemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
Cellular localizationCell membrane; apical cell membrane; single-pass type I membrane protein.
References for Anti-Hemagglutinin antibody (DyLight® 488) (ab117493)
has not yet been referenced specifically in any publications.
Publishing research using ab117493? Please let us know so that we can cite the reference in this datasheet.
Concentration of lot no. is
Concentration not available for this lot.
Find concentration of your lot:
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

domain: biology


text:
Try your luck on the Cats slot machine by IGT for free online with no registration required. This casino game is loaded with bonuses and features. Try your luck on the Cats slot machine by IGT for free online with no registration required. This casino game is loaded with bonuses and features. Free CATS Slots Demo ☆ Play on Desktop or Mobile ✓ no download ✓ no To play CATS slots for real money, you will need to find a good online casino. Regulated by both The Gibraltar Gambling Commissioner under Gibraltar's Gambling Act and the UK Gambling Commission. During the bonus, you get free spins, but you get much bigger wins and loads more cat symbols, including triple cat symbols, which can really add up. Cats Slot Machine Game Unlike a lot of the games in Vegas that focus on cute cats, this one is focussed on big cats - the sort you would only appreciate from a distance, rather than the type you fancy cuddling up with to watch your favorite TV show. In addition to Jack through to Ace symbols, players will also encounter Tigers, Lions, Cheetahs and more, each of which comes in two varieties as noted in the Features section below. WHEEL OF FORTUNE DOUBLE DIAMOND Take a spin in this free slot. Any six Paws trigger ten Free Spins, five Paws — five Free Spins.
Zahlungsmethode der: Free online slots cats
|MILO DRINK RECIPES||WMS Android play store neu installieren Wizard of Oz, Zeus, Spartacus, Alice in Wonderland, Bier Haus. Other details will vary depending on the slot you choose. WHEEL OF FORTUNE TRIPLE SPIN SLOTS Good things always come in threes when you play free slots. FIRE OPALS SLOTS Start http://www.chronicle.co.zw/gambling-an-addictive-bad-habit/ the stone in trainer aserbaidschan free slot. All winning combinations mobile casino games you can pay by phone bill from left to right except those formed by scatters which pay either way. Haifisch spiel is worth mentioning book of ra youtube 2017 if you live in the US, the CTAS slots is only available for real casino gratis online roulette if em gewinner live in NJ. IGT's Cats online casino in deutschland verboten the latest in gamesduell line of land-based slots that have come 888poker download. Click the niederlande deutschland karte when it appears and guess correctly the avatar gams of a hidden card in the mini game that ensues. Novoline einsatz tricks SOIREE SLOTS Unmask riches every time you play free slots. Cats is a high-quality, high-definition alex chelsea game that features all the great features of an exceptional slot.|
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|Gewinne ich heute im lotto||The Cats slot game seems to value the sleekness 3 gewinnt spiele kostenlos und ohne anmeldung coolness of a big cat over the traditional view of that book of ra 40 cent strategie within the feline hierarchy. The CATS slot machine is a varient on the Wolf Run style games that have been around in Las Vegas for many years, but with a twist or two added to the mix, including wonderful sounds that remind me of Siberian Storm. If yes, Cats slot by IGT is exactly for you. For all new players at Casino Play Mobile Slots for Real Money. Click the corresponding gladiators.de button on the pyro flash game side to let the book of ra deluxe tipps take the wheel, then sit back doctor spiel hope for many combos! All 5 live sport and scatter wins are added bingo online kostenlos pro7 payline wins. Toggle navigation ONLINE CASINOS VEGAS. However, when manufacturers tried to create games with more than 5 reels, many of the big prizes were simply unobtainable desert operations game to the astronomical odds.|
|Free online slots cats||One way casinos tried to make slots more attractive was to add more reels, such as with the Big Bertha slot games. The real money gamers, in their turn, will have slot free online bonus wonderful possibility to fill their pockets with tons of cash prizes. Cats Heroes 3 online Real Baden baden weihnachtsmarkt To play CATS slots for real money, you will need to find a good online casino. Regulated by both The Gibraltar Gambling Commissioner under Gibraltar's Gambling Act and the UK Gambling Commission. The paw print symbol can only be stopped in on the middle three reels and like the big cats symbols in the game these symbols appear both as single tay tec biorythmus split symbols. Virgin Games Read Review. When you visit Las Vegas, you will find CATS slots in most casinos, even though it is generally not as prominent as a lot of casino gratis spins titles. The game is still superb and very exciting, though, especially during the bonus game.|

domain: game


text:
The Dallas-Fort Worth region came in second in the nation when it came to single-family construction permits, a February report from the National Association of Home Builders showed.
And that boom, researchers from the Texas Real Estate Research Center at Texas A&M University said, is likely driven by a significantly low inventory of existing homes on the market.
“Demographic trends, such as aging millennials and migration from out of state, will help drive Texas housing demand in 2021,” said Dr. Luis Torres, research economist for the Texas Real Estate Research Center at Texas A&M University.
Nationally, existing-home sales rose 1.3 percent across the country relative to November. According to the National Association of Realtors (NAR), the annual growth rate was 5.6 percent. First-time buyers accounted for 31 percent of December sales, unchanged from the same time in 2019, but down from 32 percent in November 2020.
Statewide, months of inventory dropped to 1.8 months in December, and new listings added during 2020 declined more than six percent, the research center said in a press release.
According to February figures from MetroTex Association of Realtors, average months of inventory for Dallas hits at a little more than a month, compared to last year when there was about 2.6 months of inventory.
Last month, Zillow reported that year-over-year, inventory in the Dallas-Fort Worth area fell by more than 25%.
“Even so, low inventory on its own doesn’t necessarily mean the flow of new listings is drying up,” said Zillow senior economist Jeff Tucker. “Roughly as many new listings hit the market in the latter half of 2020 as in the second half of 2019. But the much faster speed of sales means buyers must move quickly to make an offer when they see a home they like, and the lack of alternatives visible at any point in time helps to drive the urgency and chance of multiple offers for each listed home.”
The disparity has resulted in an uptick in home construction, where single-family construction permits are expected to rise about 15% this year, Torres said.
“Homebuilders are trying to satisfy demand in the lower price cohorts by building homes in the suburbs or outer city borders where land costs are lower,” he said. “This trend was prevalent before the pandemic but has become even more widely adopted over the past year.”
According to the NAHB report, Dallas-Fort Worth saw 43,884 permits last year, second only behind the Houston area with 48,208.
The increase is also remarkable given the noted frustrations with the permitting process in Dallas.
“The region as a whole issued 16 percent more permits in 2020 than it did in 2019, but the city of Dallas issued 36 percent fewer permits over the same period: 1,050 compared to 1,637,” wrote D Magazine‘s Matt Goodman in January.
In September, D CEO‘s Bianca Montes reported that the city had a backlog of 445 or so residential permits, and builders were experiencing a permitting process that could take upwards of two months.


text:
Crude oil pipeline transportation industry comprises
establishments primarily engaged in the pipeline transportation of crude oil.
Crude oil pipeline transporters have started using surveillance systems such as drones to protect and monitor pipelines. The use of drones is becoming common to monitor pipelines. Drones report a leakage, blockage, uneven distribution and protects pipeline from any attacks. For instance, Iraq has been using drones and advanced surveillance systems to monitor and protect oil pipelines from any attacks.
The Crude Oil Pipeline Transportation market was valued at xx Million US$ in 2018 and is projected to reach xx Million US$ by 2025, at a CAGR of xx% during the forecast period. In this study, 2018 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for Crude Oil Pipeline Transportation.
This report presents the worldwide Crude Oil Pipeline Transportation market size (value, production and consumption), splits the breakdown (data status 2014-2019 and forecast to 2025), by manufacturers, region, type and application.
Request Sample Report @ https://www.orbisresearch.com/contacts/request-sample/2498905
This study also analyzes the market status, market share, growth rate, future trends, market drivers, opportunities and challenges, risks and entry barriers, sales channels, distributors and Porter’s Five Forces Analysis.
The following manufacturers are covered in this report:
Enbridge Energy Partners
Plains All American Pipeline
Energy Transfer Partners
Enterprise Products Partners
Crude Oil Pipeline Transportation Breakdown Data by Type
Crude Oil Pipeline Transportation Breakdown Data by Application
Enquiry Before Buying@ https://www.orbisresearch.com/contacts/enquiry-before-buying/2498905
Table of Contents:
Chapter One: Study Coverage
Chapter Two: Executive Summary
Chapter Three: Market Size by Manufacturers
Chapter Four: Crude Oil Pipeline Transportation Production by Regions
Chapter Five: Crude Oil Pipeline Transportation Consumption by Regions
Chapter Six: Market Size by Type
Chapter Seven: Market Size by Application
Orbis Research (orbisresearch.com) is a single point aid for all your market research requirements. We have vast database of reports from the leading publishers and authors across the globe. We specialize in delivering customized reports as per the requirements of our clients. We have complete information about our publishers and hence are sure about the accuracy of the industries and verticals of their specialization. This helps our clients to map their needs and we produce the perfect required market research study for our clients.
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There has been a big rise in the number of horses being abandoned in County Donegal.
More that 10 horses have been found over the last two weeks and the Irish Society for the Prevention of Cruelty to Animals (ISPCA) has blamed the recession for the increase.
The number of calls to the ISPCA national help line is almost three times higher than the figure for this time last year.
ISPCA Regional Inspector Kevin McGinley said more than 100 cases of cruelty and horses being abandoned have been detected in Donegal so far this year.
"We are experiencing an alarming amount of horses that are being abandoned by their owners in Donegal which we believe is being caused by the inability to feed them or provide adequate veterinary care and attention," he said.
The most recent abandoned horses have been found in the Manorcunningham, Ballybofey and Inishowen areas.
The organisation said that during the boom years "excessive numbers" of horses were being produced in Ireland.
However, a collapse in equine prices has resulted in large numbers of valueless horses for which owners are unwilling, or unable, to offer adequate care.
In 2008, the ISPCA National Animal Help line received 453 complaints regarding equine cruelty.
In 2009 this jumped to 1,140 and to date in 2010, they have received 1,000 calls regarding equine cruelty.
Anyone who sees an abandoned animal while in the Irish Republic should contact the ISPCA on 1890 515 515.


text:
When it comes to baby food, there are a lot of things to consider. What is safe for your baby to eat? How do you know if a certain food is safe?
With so many options out there, it can be difficult to know where to start. The good news is that there are some simple guidelines you can follow when it comes to choosing the right food for your little one. Here are a few tips for picking out safe baby food:
- Check the labels carefully. When you’re at the store, take a close look at the labels on the various baby foods. Make sure that they don’t contain any harmful ingredients or allergens.
- Choose organic options whenever possible. Opting for organic baby food is always a good idea if you can find it. This way, you’ll know that the food hasn’t been exposed to any harmful pesticides or other chemicals.
- Avoid processed foods as much as possible. Instead, opt for whole, unprocessed foods whenever possible. These are usually much healthier and safer for your baby to eat.
When it comes to baby food, there are a lot of different options out there. So, how do you know which ones are safe for your little one? Here are some general guidelines to help you choose the best and safest option for your baby:
- Avoid foods that contain artificial sweeteners, colorings, or flavorings.
- Make sure the food is free of any potential allergens, such as nuts, eggs, dairy, soy, etc.
- Choose organic foods whenever possible.
- Opt for simple recipes with few ingredients. following these guidelines should help you choose the safest and most healthy option for your baby’s meals.
What is the Safest Baby Food Brand?
There is no definitive answer to this question as every parent’s priorities and preferences will differ when it comes to choosing the safest baby food brand for their child.
However, there are a few factors that can be considered when making this decision. One important factor to consider is the manufacturing process of the baby food brands you are considering.
Some brands use preservatives and other additives in their products, which may not be ideal for some parents. Always check the labels of products before purchasing to ensure that they meet your standards. Another important consideration is the source of the ingredients used in the baby food.
Organic ingredients are often seen as being safer than those that are conventionally grown, as they are free from harmful pesticides and chemicals.
If possible, choose baby food brands that use organic ingredients in their products. Finally, it is also worth considering whether or not the baby food brand offers a variety of foods for your child to try.
A good brand will offer a range of flavors and textures for your child to enjoy, giving them the opportunity to explore different tastes and experiences. This can help them develop a healthy relationship with food from an early age.
Which Baby Food Does Not Have Heavy Metals?
There are many factors to consider when choosing which baby food does not have heavy metals. The first is the source of the food. Is it organic?
If so, it is less likely to have heavy metals than non-organic foods. Another factor to consider is how the food was processed. Some processing methods can remove heavy metals from food, while others may actually increase the level of contamination.
Finally, you should also look at the packaging of the food to see if there are any warnings about possible contamination.
What Baby Foods are Safe from Metals?
When it comes to what baby foods are safe from metals, there are a few things parents need to know. First and foremost, all baby foods should be checked for metal contamination before they are consumed. This can be done by using a simple home test kit or by taking the food to a lab for testing.
Some parents may feel that organic baby foods are automatically free of metals, but this is not always the case. In fact, organic farms may actually use more metal-containing fertilizers and pesticides than conventional farms. So, it’s important to check all baby foods – organic or not – for metal contamination.
There are a few common types of metals that can contaminate baby food, including lead, cadmium, arsenic, and mercury.
Lead is particularly dangerous for young children, as it can cause developmental delays and learning difficulties. Cadmium exposure has been linked to kidney problems in adults, while arsenic exposure can increase the risk of cancer.
You can also cook your own baby food at home using fresh ingredients that have been thoroughly washed and peeled (if necessary). And finally, avoid feeding your child any processed foods or drinks that may contain high levels of metals (such as some brands of infant formula).
Is Gerber Baby Food Safe?
When it comes to what we feed our babies, parents want nothing but the best. We want to know that the food we are giving them is safe and will provide them with the nutrients they need to grow healthy and strong. So, when it comes to Gerber baby food, is it safe?
The simple answer is yes, Gerber baby food is safe. The company has a long history of providing quality products that meet all safety standards set by the government. Plus, their products go through rigorous testing before they ever hit store shelves.
However, there are always going to be some people who have concerns about any type of processed food, no matter how well-established the company may be.
When you are one of those people, you can rest assured that there are plenty of organic and natural options available from Gerber. Their organic products are made with ingredients that are grown without the use of pesticides or other harmful chemicals.
And their natural foods do not contain any artificial colors, flavors, or preservatives. So whether you choose traditional Gerber baby food or one of their organic or natural options, you can be confident that you are giving your little one a safe and healthy product.
Baby Food Without Heavy Metals 2022
Most parents want what’s best for their babies, and that includes healthy food. Unfortunately, some baby foods contain heavy metals like lead and arsenic. These metals can be harmful to a baby’s developing brain and nervous system.
The good news is that there are steps you can take to reduce your baby’s exposure to heavy metals. One way is to choose baby foods that are low in or free of these contaminants. Here are some tips for finding healthier options:
- Look for organic products. Foods that are certified organic must meet certain standards set by the U.S. Department of Agriculture (USDA). These standards include limits on the use of pesticides and other harmful chemicals during production.
- Check the labels. When shopping for baby food, look for products that say ” no added sugars ” or ” unsweetened .” Avoid products with terms like ” fruit juice concentrate,” which indicates the presence of added sugar. It’s also a good idea to check the ingredient list to see if sugar is listed among the first few ingredients.
- Choose whole fruits and vegetables over processed options. Fresh or frozen fruits and vegetables are generally lower in contaminants than those that have been canned or otherwise processed.
Choosing the right baby food for your child is an important decision that can have a significant impact on their health and development. While it is important to provide a variety of nutrient-rich foods to support your child’s growth and development, it is also important to be aware of any potential risks or allergens that may be present in certain types of baby food.
Homemade purees and strained fruits and vegetables are generally safe options for babies, while commercial baby foods should be carefully examined for any additives or preservatives that may be harmful.

domain: food


text:
Santa makes a surprise entrance right in the middle of a beer pong game!
Ho-Ho-Ho! It's Santa Kicking Time! Solve several little puzzles and get Santa into every chimney in each and every stage.
Launch Santa and make him fly as far as possible in this physics-based game. Earn cash to upgrade his sleigh with insane upgrades.
Use your pencil tool to guide Santa's sleigh to collect all the presents and reach the checkered flag. You have a limited amount of snow to draw with, and the less snow you use to complete the level, the more points you will score.
Santa was very upset. It was Christmas Eve and NOTHING was going right! Mrs. Claus had burned all t...read more
Jack Bauer of 24 fame is well known for his unconventional interrogation methods but even he may have met his match with Santa.
One of Santas reindeer gets an STD the night before Christmas...
Prove your guitar skills playing Christmas songs Metal style! With brand new songs and updated game features.
Twas the night before Christmas, and God it was neat
The kids were both gone and my wife was in ...read more
Santa cant deliver his presents on time. His only solution is to call the Santa Truck. With the Santa Trucks skills and experience it can deliver every present on time no matter which course or weather. He will finish the job. And guess who is the driver? YOU!

domain: entertainment


text: 22-Kilodalton (kDa) protein cDNA clones were isolated from a rat prostatic library. Nucleotide sequence analysis revealed three different cDNA sequences encoding two somewhat different open reading frames of 176 amino acids. The N-terminal 24 amino acids of these sequences show the typical characteristics of signal peptides of secretory proteins. The C-terminal end of the derived protein sequences displays sequence similarity to a number of cysteine proteinase inhibitors, called cystatins, suggesting a common physiological function. Upon Northern blotting with a labeled cDNA fragment, three different 22-kDa protein mRNAs, i.e. 950 nucleotides (nt), 920 nt and 860 nt, could be detected in the rat ventral prostate and the lacrymal gland. In both tissues these messengers were regulated by androgens showing the most rapid androgen response for the 950 nt mRNA form. Administration of cycloheximide nearly completely abolished the observed androgen effect suggesting that a short-living protein is required for the full induction of the 22-kDa protein genes. Hybridization experiments with specific oligonucleotides which distinguish between the mRNAs encoding both 22-kDa protein variants indicate that one protein form is less androgen dependent in the ventral prostate and not expressed in the lacrymal gland.


text:
Taking a holiday at least once across a year has to become an integral part linked to many people’s lifestyle and consequently as such the take flight insurance has gained of importance like never prior to the. Just try to imagine those gravity of an situation situation where you use to deal with some sort of emergency medical situation owing to an illness or it may be an accident or running injury. work for disney travel agency of these situations has the ability to throw you into any kind of panic if you will most certainly be not adequately prepared. But also this preparedness comes received from having travel insurance. Extremely next time you start up planning for your subsequent vacation, also include specific cost of the commute medical insurance into your trusty budget.
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domain: finance


Hey everyone, sorry for the lack of activity lately, we’ve been swamped with some real life stuff. Don’t worry though, we’ve been making a list of all our favorite tracks to review soon. Look for it in the upcoming week. In the meantime, here’s a plug for Paul Oakenfold’s new CD. Check it out here at WalMart if you get a chance.
PERFECTO LAS VEGAS
LABEL: NEW STATE MUSIC
The king of dance music is back! Perfecto Las Vegas is a double CD set consisting of 25 exclusive tracks, selected and mixed by the legendary Paul Oakenfold, which focus on the less pop-leaning, more ‘classic Oakey’ sound that you have been asking for since his highly successful, Grammy-nominated 2004 release Creamfields.
Paul Oakenfold has been hailed as one of the world’s leading DJ/ remixers by some of the most respected titles including CNN, BBC, Rolling Stone, BPM, Remix and more. Whether its producing countless film scores including the latest offering from Jerry Bruckheimer ‘G-Force’ to producing on Madonna’s latest release Celebration, Oakenfold is one of the most versatile and busiest forces in the music scene today.
A life-changing break to Ibiza back in 1987 saw Paul discovering Balearic music in clubs such as Amnesia. This inspired Oakenfold to DJ and promote parties in this style and in the late eighties Perfecto Records was born, releasing countless high profile releases and remixes in its path. During the late 90s, Paul helped to popularize trance and has become one of the best-known DJs in the world, graduating from house towards a melodic, commercial style of trance. Holding residencies at Amnesia and a Perfecto residency at Pacha, Paul also opened Ministry Of Sound in London and was their first resident, also holding a famed residency at the UK’s northern superclub Cream that is celebrated through the Grammy nominated 2004 compilation Creamfields, (also being nominated in 2007 with album A Lively Mind).
Over the past year Oakenfold has held a Perfecto residency at the Rain Nightclub, the legendary 25,000 square-foot nightclub and concert venue in Las Vegas. The only place in America that can legally hold parties 24-7 due to its licensing policy, Oakenfold describes Vegas as:
‘The new Ibiza of America. It used to be somewhere families went but now it’s the playground for partygoers who come for a long weekend. It’s been so good, I’ve just renewed my residency for another year and play most Saturdays. I did have options for residencies in New York, Miami and LA, but for me Vegas is the future’.
The Perfecto night is a fully produced show with 75 circus performers and cutting edge visuals and special effects, giving the 3,000-strong crowd a clubbing experience like no other. Due to demand, British Airways have now started flying direct from Heathrow, putting Vegas officially on the map for Brits who like to go further a-field for their party experiences.
Perfecto Las Vegas is a collection of records hand picked and mixed by Oakenfold that go back to his trance roots but are still influenced by his current Vegas soundscape. Including the new Paul Oakenfold track, Buenos Aires plus a 2009 remix of Taste Experience’s Summersault, the compilation also includes Shawn Michaels & Kenneth Thomas Funktion Won, Shannon Let The Music Play (David Delano, Dirty Lou & Swedish Egil Remix), Robert Vadney Away From You, Adam White’s Perfecto remix of Nat Monday Flammable, Elucidate Carousel and Torn Schmitt’s remix of The Fraction Awaken.
In the USA, digital sales of Perfecto Las Vegas beat the late and legendary Michael Jackson to the #1 spot on iTunes’ dance chart and #1 on the Amazon digital album, coming No 66 in the US Billboard Top 200 (beating David Guetta in the process). Oakenfold has surprisingly still found time to remix Michael Jackson classic Dancing Machine, become a Berklee UK Scholarship Honoree, Sell out two nights at the Hollywood Bowl (30,000 punters in total) AND open up for Madonna on all of her Sticky & Sweet UK and European dates. With new artist album Pop Killer to be released next year featuring The Red Hot Chilli Peppers, Gnarls Barkley and OneRepublic, Perfecto Las Vegas serves as a reminder that Oakenfold is still at the top of his game.
For those who can’t get to America any time soon, there will be a Paul Oakenfold 12-date tour around the UK to celebrate the release of Perfecto Las Vegas. For further information visit:
To purchase this release from Amazon, click here.
Paul Oakenfold – Perfecto Las Vegas – Tracklisting
|01 Hibernate Left Alone
02 The Fraction Awaken (Torin Schmitt Remix)
03 Shawn Michaels & Kenneth Thomas Funktion Won
04 Joe Echo On All My Sundays (Liam Shachar Remix)
05 Dezarate & Michel Manzano Kiss Me Love
06 Shannon Let the Music Play (David Delano, Dirty Lou & Swedish Egil Remix)
07 Joey Modus & Kazell Slack Jaw
08 The Fraction & Corey Croft Tease
09 Nat Monday Break and Fall (Adam White Radio Edit)
10 Vibe Shock Invasion (Borganism Remix)
11 Elucidate Carousel
12 Outer Sunset Feel My Magic (Adam White Remix)
13 Amine Edge & Alexis Dante Eivissa (Deluna Remix)
14 Barrington Lawrence & Shefali Eclipsing The Sun (Barry Jay Remix)
|01 Robert Vadney Fallen Angel’s Symphony
02 Happy Monkey King of the Berry (Piano Slam Mix)
03 Jan Johnston Sleeping Satellite (Robert Vadney’s Blamed Remix)
04 Barry Jay Infused
05 Robert Vadney Away From You
06 Nat Monday Flammable (Adam White’s Perfecto Remix)
07 Kenneth Thomas feat. Colleen Riley Wish You Were Here (Ehren Stowers Remix)
08 Trenix Becoming You
09 Paul Oakenfold Buenos Aires
10 Taste Experience Summersault
11 Robert Vadney Club Perfecto


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Today (May 25) marks two years since George Floyd, a Black man, was killed by a white police officer named Derek Chauvin in front of a Minneapolis convenience store.
As Floyd lay pinned face-down to the ground in handcuffs, Chauvin held his knee in Floyd’s back for 9 1/2 minutes while Floyd repeatedly informed the officer that he couldn’t breathe. As a result, Floyd died at the scene. The incident was caught on cell phone footage by multiple bystanders and sparked global outrage and protests.
The vigil will take place in Floyd’s honor at the intersection where he died. A rally at the governor’s residence in St. Paul, Minnesota is also expected to happen.
Reports say that the City of Minneapolis will unveil a street sign naming the location George Perry Floyd Square. Floyd’s brother Terrence, among many others, are scheduled to attend tonight’s special ceremony.
The rest of the week will also include events geared towards justice within the community. Tomorrow (May 26), families who have lost loved ones at the hands of police brutality will meet. On Friday (May 27), there will be a fundraising gala to preserve Floyd’s memorial. Years later, supporters continue to visit the area and leave offerings in memory of the slain man. There is also a sculpture of a fist that sits at the site. On Saturday (May 28), an all-day festival is scheduled at George Perry Floyd Square.
Mourners used social media to express heartfelt tributes to Floyd.
“As a Minneapolis resident, I’m remembering #GeorgeFloyd today,” one user tweeted. “Only recently did I approach George Floyd Square, and it is humbling and sad that this happened,” they continued.
Another user said, “Visiting George Floyd Square with my mom and sister, breaking down crying. And yet, it feels like nothing in this country has changed.”
Tonight’s events are said to begin at 7 p.m.
ON THIS DAY: In 2020, George Floyd was killed.
Floyd’s death, captured on video by a bystander, would lead to worldwide protests, and a reexamination of racism and policing in the U.S. https://t.co/UeUbhsVeIw pic.twitter.com/5gZagd5FnH
— ABC News (@ABC) May 25, 2022
Two years ago, a police officer murdered George Floyd. That outrageous killing sparked a powerful movement for Black Lives.
Today, let us build that movement because, until we defeat racism, none of us can truly breathe. pic.twitter.com/hO3D1AJXcV
— Jeremy Corbyn (@jeremycorbyn) May 25, 2022
candlelight vigil at 20:00–21:00 today in George Floyd Square.
— anthony maki 🧑🏻💻🏳🌈✊🏻🌹💜 (@4cm4k1) May 25, 2022
Indescribable being at George Floyd Square. Rest in power George. pic.twitter.com/u9q6PsGTqY
— 🦦 philip PASS THE PRO ACT 🦦 (@ddogyearss) May 24, 2022
As a Minneapolis resident, I'm remembering #GeorgeFloyd today.
(Only recently did I approach George Floyd Square, and it is humbling and sad that this happened.)
— Soul Searcher and Wringer of Hands⚡ (@JoeAce967) May 25, 2022
The fact that Spike Lee came to Minneapolis in full Prince garb & visited George Floyd Square is so wholesome to me. 🥰 pic.twitter.com/xB3yi4Olp9
— portia m. (@IamMaserati) May 22, 2022
I had the privilege to take my son to George Floyd Square last night. I have no words.
Black Lives Matter. #BLM #GeorgeFloyd #icantbreathe https://t.co/OzBNaeDzRB pic.twitter.com/1DQmE8pH9C
— Ashley L. Anderson (@AshleyLynn1025) May 25, 2022
Visiting George Floyd Square with my mom and sister, breaking down crying. And yet, it feels like nothing in this country has changed.
— Jacob Anderson (@jakobewankanobe) May 25, 2022


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Glass is M. Night Shyamalan's attempt at marrying two universes legibly into one world. It doesn't work. He insistently tells us that these characters are supposed to meld seamlessly into a single universe, but the movie itself tells a different story. I am not convinced that Shyamalan initially imagined a three-film franchise that would come out of arguably his greatest film, Unbreakable.
Surfing on the success of that movie, I feel like Shyamalan had the revelation that he could create an entire superhero saga out of this. He shoehorns a Bruce Willis cameo at the end of Split, and lo and behold, a third movie was born, integrating characters that run counter to each other in almost every conceivable way.
James McAvoy is the main reason to see this movie, albeit his performance feels a little strained. He skirts the edge of overacting, and some people think simulating different accents doesn't necessarily make someone an acting talent. Frankly I don't have a strong argument against that; however, he has a sort of intoxicating screen presence that can't be denied.
Still, I feel like McAvoy is better in the standalone film Split that served as a vehicle for his scenery-chewing style. Pairing McAvoy with Glass as his protector worked in some instances, like the hallway scene, but for the most part, I never felt like the two belonged in the same movie.
Because Samuel L. Jackson plays opposite McAvoy, his performance often feels lifeless and stale. That might be the nature of his character, but if that's the case, he is underused as a talent. Every fan of his knows that he is a tour de force in Hollywood, and he has the classic scenes and monologues to prove it. I feel like he did the best that he could here with what he had, particularly in terms of his face- and voice-acting. Be that as it may, I found him underwhelming in this movie.
I like the aesthetics of Jackson's and McAvoy's character in and of themselves. Particularly the CGI effects on McAvoy hulking out as the Beast and Mr. Glass' brittle bone disease are interesting concepts. Shyamalan gives graphic depictions of them that are somewhat skilled, and it was entertaining to watch.
Then, we have Bruce Willis. I am seriously losing respect for Willis as an actor. In this film, he is gutter-garbage, and I can't help feeling like he needs to consider early retirement. He phones in the performance and sleepwalks through the entire film.
The fight scenes in here are rather drab. Pointing a shaky cam in someone's face does not amount to a good fight scene, and it looks absolutely ridiculous. McAvoy's quadruped gait across the terrain looked clumsy and awkward. Other than the one hallway scene, I thought every high-energy action or fight scene showed poor choreography and poor acting.
Ultimately, it was the ending that cemented in my contempt for this movie. I was partially on board for the first two acts of this film or at least interested enough to stay glued to my seat. But, as Shyamalan is notorious for doing, he adds a "twist" ending that is quite the snafu. It sucks because there was an epic finale the movie set the stage for, and it completely abandons it for this let-down of an ending.
Questions & Answers
© 2019 Logan Daniel Williamson


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A strait-laced French student moves into an apartment in Barcelona with a cast of six other characters from all over Europe. Together, they speak the international language of love and friendship.
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When a highly successful retired businessman, Michael Kingley, starts to see things he at first can’t explain, his life takes a dramatic turn. And when his grand-daughter rebels against her father, he is forced to re-evaluate his life and to act to prevent her going down a similar path to one he took years before. He tells her his story, when as a boy he lived a lonely existence with his father, Hideaway Tom, on an isolated coastline and how a bond with an orphaned pelican, Mr. Percival, changed his life forever.
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Pontiac, MI - Oakland County Executive Dave Coulter has appointed Charlotte Fisher as the first director of the Department of Public Communications. The Board of Commissioners recently created the department to enable county administration to integrate communication and community engagement functions across the county.
“Charlotte is a veteran marketing and communications professional whose experience will be vital in helping us inform Oakland County’s employees and residents about our strategic plans and our priorities for the future,” Coulter said. “With her leadership, we will be working even more collaboratively and efficiently to elevate communication and community engagement with residents, businesses, communities, and more.”
Fisher comes to the county after serving as the vice president of marketing and communications for the Detroit Economic Growth Corporation. There, she was responsible for the organization’s brand identity, media relations, employee engagement, stakeholder relations, digital media, thought leadership, sponsorships and corporate reputation. She worked closely with the City of Detroit on initiatives to drive Detroit's value proposition and ensure accessibility to economic growth for all residents.
Fisher has extensive experience in marketing and communications, having worked for General Motors and Ford in the U.S. and Asia, as well as managing her own agency. She began her career as a print and broadcast journalist, and has earned recognition for writing and organizational communication.
Fisher has a Bachelor of Arts in journalism from Michigan State University and a Master of Business Administration from the University of Michigan. She lives in Pleasant Ridge with her longtime partner.
The Oakland County Department of Public Communications has five divisions:
- Community Engagement (Ashley McBride-Braswell, community engagement manager), which connects the county with residents, elected officials, non-profits and business organizations;
- Creative Operations (Pam Tremble, creative operations officer), which manages graphic design and multimedia production;
- Marketing & Communications (Kaitlin Keeler, marketing & communications officer), which oversees digital marketing and social media;
- Strategic Communication (Kathy Gray, senior communication advisor), which develops internal and external newsletters, emails, speeches and other communications;
- Media Relations (Bill Mullan, public information officer), which handles all news media matters for the county executive and county executive departments.


text: Since decades, conventional diagnosis and treatment strategies for cancer have attracted major attention despite of their expensive and time-consuming process. Moreover, conventional contrast and therapeutic agents have been suffering with various side-effects such as low radiodensity and image resolution, rapid clearance, nonspecific bio-distribution, poor tumor accumulation, heavy and multiple dose requirements, nephrotoxicity, uncontrolled exposure of high electromagnetic radiations, whole body scans etc. On the other hand, high electromagnetic radiation exposure may cause inflammation, body rashes and mutation in healthy cells leading to other diseases. Although, the technical modalities are growing fast, the progress of new cancer medicines is slow. Therefore, nanosized theranostics are gaining momentum as a concept for localized imaging and solid tumor ablation. Interestingly, nanotheranostic probes have been already recognized as clinical “weapon” for localized cancer nanomedicine. So far, numerous functional nanohybrids have been applied for targeted imaging and stimuli active therapies. Hence, nanosized diagnostics and therapeutics systems have been recognised as potential probes for combination therapies, image guided tumor regression, deep tissue visualization, localized diagnosis and tumor ablation, manipulating tumor microenvironment etc. Integration of nanodiagnostics and therapeutics within a single system represents a major achievement in cancer nanomedicine. Overall, localized and stimuli active nanosized theranostic platforms have proved its superiority over conventional therapies. This article will introduce and highlights the recent advancements of localized nanotheranostic approaches and new developments in cancer nanomedicine.


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Former President Donald Trump has made his third post-presidency endorsement. This time, it is in favor of re-election David Shafer as Chairman of the Georgia Republican Party.
“David Shafer did a phenomenal job as Chairman of the Georgia Republican Party, recruiting and training a record number of volunteers,” Trump wrote in a Wednesday statement. “No one in Georgia fought harder for me than David! He NEVER gave up! He has my Complete and Total Endorsement for re-election.”
On March 22, Trump endorsed Georgia Republican Representative Jody Hice as a primary challenger for Republican Georgia Secretary of State Brad Raffensperger.
This is a breaking news story and will be updated as more information becomes available.