text:
Nestlé’s vegan and vegetarian brand Garden Gourmet will soon hit store shelves in the United Kingdom. Sainsbury’s and Ocado will be the first supermarkets to stock the meat-free meals.
The move will assist Nestlé in taking “a bite out of the booming plant-based meat alternative market,” according to media publication The Grocer.
The range is made up of 12 products in four categories: Familiar Swaps, Veggie Creations, Just Ingredients, and Snack On. The line includes frozen and chilled food items, including meat-free patties, falafel, chicken-style fillets, and broccoli bakes, with more products in development.
The brand is not considered vegan since some of its products contain cheese and egg, however, Garden Gourmet has produced a range of vegan items, including Quinoa Kale Burgers, Filet Pieces, Falafel Spinach, Falafel Beetroot, Mince, Hamburgers, and Chorizo, among others, which are completely free from animal products. It is not yet clear which vegan-friendly products will appear in Sainsbury’s and Ocado.
Both the dairy and the egg industry have faced backlash in recent times as an increasing number of people recognise the ethical complications associated with using animals for food. The cruelty towards animals, the industry’s environmental impact, and health problems linked to eggs and dairy have led to more people than ever ditching the food items. Research finds that almost 30 percent of the UK want to give up cheese and cow’s milk in 2018.
Nestlé told The Grocer that the Garden Gourmet range provides “delicious and heathy meat-free products for food lovers looking to cut down on meat but not wanting to compromise on taste.”
Paula Jordan, the Managing Director of Nestlé’s UK Food Division added that the brand will “revolutionise the vegetarian category.” She added, “We find that people want to enjoy a healthier diet and try to eat less meat, but they are sometimes disappointed with the taste.” Jordan also pointed out that a high number (80 percent) of shoppers that are new to meat-free eating give up early on due to problems with availability, taste, and texture. However, Garden Gourmet is said to offer a “versatile range of delicious meat-free products packed with flavour to make sure there is no need to compromise on taste ever again.”
Garden Gourmet launched in Israel in 1986. Nestlé invested in the brand early on in its trajectory and acquired it entirely last year, The Grocer noted. Nestlé also invested in plant-based organic snack company Terrafertil earlier this year and acquired vegetarian ready-made meal brand Sweet Earth last year. Regarding the acquisition, co-founder of Sweet Earth, Kelly Swette, told FoodNavigator, “Big food companies such as Nestlé have to be part of the change, so this deal is a validation.”
Patrice Bula, EVP of strategic business units, marketing, and sales at Nestlé previously said, “We want to bring a vegetarian offer to consumers in Europe and the Western World and ride on this trend that we believe is here to stay and amplify.”
The products are set to appear in Sainsbury’s and Ocado on May 27.
Image Credit: Garden Gourmet


text:
Purpose: Neonatal mastitis is a rare but challenging problem that commonly appears within the
first 8 weeks after birth. Abscess formation in an infant’s breast can lead to acute complications and longterm
dysfunction. To our knowledge, no publication focuses on surgical techniques and postoperative care
to avoid breast scarring in neonates. We herein present our surgical approach by periareolar drainage to
avoid this long term complications.
Methods: After reviewing the medical database of our hospital from 2002 to 2012, 11 cases (6 females and
5 males; 10 unilateral and 1 bilateral) of neonatal mastitis were found. Four cases required surgery, performed by periareolar
drainage (n = 4, 4:11). Our data were compared with data obtained from a literature review using Medline and Cochrane
Results: In all our patients that underwent surgery, clinical symptoms were reduced directly after surgery. Our results
were comparable with those reported in the literature, which included 163 patients (105 [64.42%] required surgery) from
seven publications. Regarding our surgical technique, we have not observed any long-term complications during follow
up examinations (range 12–116 months postoperative; mean, 77.36 months), which have been reported in the literature.
Conclusions: Even if the acute infection can be cured by parenteral antibiotics and surgical incision if necessary, the longterm
problems of scarring after mastitis, especially from surgical incisions at the site of maximum swelling, can lead to
severe functional and aesthetic problems. To avoid such scarring, we herein present our surgical approach to mastitis by

domain: medical


We have an existing website on Poets and Poetry. Through our website poets can publish Poetry.
We would like to offer an App so that people can publish their poetry on the go.
The requirement for the App is quite simple. I have listed the requirements below:
- We need the App to be developed using a Cross Platform Tool like Phone Gap so that it can be published in 3 main Marketplaces [ Android/ Windows / iStore ]
- The Graphic must be very good and Attractive and Lightweight. This is a fundamental requirement for the App.
- Users will be able to publish poems from the App. This functioality is also there in our existing website. However in existing site the functionality is not exposed as web service.
- The Home page of the App will display a Live Feed of new Poems published. This will be a realtime feed. Means lets say one user is in Home Page and at the same time there is another user in website or from the App submits a poem. It will be shown immediately to this user too. The design should be very intutive.
- Poets will be able to create their basic profiles through the App which is required for publishing. The Account creation and basic information should be updateable through Social Logins like Facebook, Google and Twitter as well (like existing site )
- When the user opens the App, they will be logged in by default and will show the home screen which will be the published poems. Any update to the poems will be synchronixed by taking permission from the user.
- discover - It will show a random selection of few poems and a search option to search the database of poems from our site. This functionality of searching is also there in the existing site.
- Notification - Admin can notify any messages to the users of the App.
- Contact - Users can contact Admin through the App
- Favourite - Users can mark poems as favourite and this list of favourite can browse at any time. Users will also be able to like a poem.
- While publishing the poems, it will be asked if it is OK to share in Facebook, on acceptance, share the poem in facebook as well.
- Advertisement - Admob code will be picked up from our database and ads will be displayed.
- Social Sharing should be possible
- Below each published poems, it will show the count of views, likes , poets name and within bracket (with hyperlink) to other poems of that poet
- Listing of poems should be possible by poets name
- Completion of the App development and publishing must be done before 30th April
Apps to be refered:
- Refer Jotterpad from Google Playstore to get a view of how a similar App works
- Refer Shpock to get an idea about Design
- Refer Poetizer - similar type of App
32 freelancers are bidding on average $385 for this job
Hi I work towards providing reliable, relevant and robust IT solutions at most competitive prices to my customers. I ensure 100% customer satisfaction so lets start Thanks


text:
This program is FREE for all pregnant women in Wyoming. We offer Presumptive Eligibility screening for Title XIX. We provide smoking cessation referral information and support as well as numerous community resources. We also discuss all of the free programs provided by the Maternal Child Health Department including; Best Beginnings, Nurse Family Partnership, Welcome Home, and Children’s Special Health.
Presumptive Eligibility (PE) for Pregnant Women is a Medicaid option designed to improve an applicant’s access to temporary Medicaid while their eligibility for full Medicaid benefits is being determined. Eligible pregnant women are limited to outpatient services through a Medicaid provider for up to 60 days after completing an application for Medicaid.
To qualify a woman must be:
Children’s Special Health is a program for infants and children with special health care needs that require more than routine and basic care. CSH provides payment for specialty medical care and coordination of care for children with an approved condition and diagnosis. The Genetic Clinics are held at Casper-Natrona County Health Department.

domain: health


text:
Scientists at the University of Sheffield have cast doubt on the validity of the controversial theory of biological cold fusion, the principle sometimes used to lend credence to the practice of selling silicon tablets to strengthen bones, on the assumption that the body will turn the silicon into calcium.
Biological cold fusion, also known as the ‘Kervran effect’, is the principle that living organisms can act as alchemists and turn one element into another. The French Scientist, Louis C. Kervran claimed that he had proven the existence of cold fusion by feeding hens with a calcium deficient diet and observing that they still laid eggs with the usual calcium rich shells. He argued that they did this by changing silicon into calcium.
In a paper published in the Spring 2003 edition of The Journal of Scientific Exploration, Dr. Milton Wainwright, of the Molecular Biology and Biotechnology Department at the University of Sheffield casts serious doubts on one of the alleged proofs of the Kervran Effect . He describes how he and his team used the common mould, Aspergillus niger, to attempt to turn manganese into iron. This was another example cited in Kervran’s work.
Lorna Branton | alfa
Scientists enlist engineered protein to battle the MERS virus
22.05.2017 | University of Toronto
Insight into enzyme's 3-D structure could cut biofuel costs
19.05.2017 | DOE/Los Alamos National Laboratory
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...
For the first time, scientists have succeeded in studying the strength of hydrogen bonds in a single molecule using an atomic force microscope. Researchers from the University of Basel’s Swiss Nanoscience Institute network have reported the results in the journal Science Advances.
Hydrogen is the most common element in the universe and is an integral part of almost all organic compounds. Molecules and sections of macromolecules are...
22.05.2017 | Event News
17.05.2017 | Event News
16.05.2017 | Event News
22.05.2017 | Materials Sciences
22.05.2017 | Life Sciences
22.05.2017 | Physics and Astronomy

domain: chemistry


After signing Wells Fargo as the anchor tenant for his 17-story office tower in downtown Spokane, Davenport Hotel owner Walt Worthy is buying the financial institution’s soon-to-be former building.
Wells Fargo plans to move out of its eight-story building on the northeast corner of Riverside and Howard by mid-2005. The bank will move into 34,000 square feet of leased space in the former Metropolitan Financial Center, which Worthy bought last summer. That building, at 601 W. First Ave., will be renamed the Wells Fargo Center and will become the new Spokane headquarters for the San Francisco-based bank.
Worthy’s purchase of Wells Fargo’s building is expected to close today or Friday, he and bank officials said. Neither party would disclose the purchase price. However, the 62,000-square-foot building and the land it sits on are assessed at $3.3 million, according to the Spokane County Assessor’s Office.
“I thought it was a good deal,” Worthy said Wednesday. “It’s about as prominent a location as you could want, and the building’s in reasonably good shape.”
The building was constructed in 1952 and has previously been called the Fidelity Building and the First Interstate Bank Building. It has 47,000 square feet of space above ground and a 15,000-square-foot basement, according to the assessor’s office.
Worthy said he’ll upgrade the building after the bank moves and will lease it out as office space. Worthy plans to install new windows and resurface the exterior. He also plans to rename it, but hasn’t decided what to call it. New names are frequently tied to anchor tenants, and Worthy said he has not secured one yet, but does have a business in mind.
“We’d like to attract a bank,” he said. “It’s a bank now, and there’s a vault there. It’s a good location for a bank to locate.”
Other parties were interested in buying the building, but Worthy offered the best overall deal, said Don Young, Eastern Washington community banking president for Wells Fargo. The bank plans to lease its space back from Worthy until its operations are moved.


text:
UA research leads to breakthrough pulmonary-infection treatment possibility05/19/2009
Dr. Wiley Youngs, UA distinguished professor of chemistry (top), joined with Dr. Yang Yun, UA assistant professor of biomedical engineering (above) and Dr. Carolyn Cannon, co-director of the Cystic Fibrosis Center, Washington University School of Medicine in St. Louis, to invent a new antibiotic treatment option for pulmonary infections.
Research on a new antibiotic treatment option for pulmonary infections including pneumonia and cystic fibrosis, developed at The University of Akron and Washington University School of Medicine, has potential for significantly increasing survival among patients with lung infections.
The nanoparticle antibiotic treatment is composed of encapsulated silver carbene complexes, or SCCs (a novel class of silver-based antimicrobials), developed by Dr. Wiley Youngs, UA distinguished professor of chemistry, with collaborators Dr. Yang Yun, UA assistant professor of biomedical engineering who developed the nanoparticle delivery system, and Dr. Carolyn Cannon, co-director of the Cystic Fibrosis Center, Washington University School of Medicine in St. Louis. The research team presented notable, treatment-related increases in survival in a mouse pneumonia model at the American Thoracic Society 2009 International Conference in San Diego on May 19.
The concentrated nanoparticles are administered once daily. According to the researchers, these nebulized antimicrobials epitomize effective and convenient drug delivery that encourages patient compliance with the treatment regimen, ensuring successful reduction of patients’ illness severity, limiting development of resistance to antibiotics and potentially decreasing the spread of epidemics.
Treatment is effective
Although all of the untreated animals died, treatment with aerosolized, nano-sized, silver-based antibiotics allowed survival of 100 percent of mice inoculated with Pseudomona aeroginosa, a common bacteria that infects the respiratory tract in humans, especially those who are immunocompromised, on mechanical ventilatory support or afflicted with cystic fibrosis. Treatment with the SCC-loaded nanoparticles also minimized weight loss and the bacteria burden in the lung and reduced the spread of bacteria from the lung through the blood stream to the spleen.
The team’s collaboration began in 2004 when Cannon approached Youngs with an inquiry about testing SCCs for their effectiveness in treating a resistant Burkholderia strain that had infected several cystic fibrosis patients in Boston. Youngs sent Cannon a methylated caffeine silver acetate compound (SCC1), which he developed at UA. The compound proved highly effective against Burkholderia dolosa and every other bacteria strain tested to date. The uniqueness of these compounds is related to their broad-spectrum activity, according to the researchers. In 2007, SCCs were encapsulated into nanoparticles with the help of Yun. This allowed their extended release formulation.
Youngs and his UA research team are embarking upon commercialization of their technology through a University of Akron Research Foundation startup venture known as Akron Research Commercialization Corp. Their first product offering —Silvamist™ — will soon be under application process with the FDA for Investigational New Drug status. Also, UA has established the Center for Silver Therapeutics Research, headquartered at the university as an academic and industry center for continued research and development of silver-based pharmaceutical candidates.
Media contact: Denise Henry, 330-972-6477 or email@example.com.

domain: news


text:
No matter which religious holiday you celebrate at this time of year -- or even if it is a purely secular one -- I want to wish you and yours, from me and mine, a most glorious holiday season.
I've had an extraordinary year but I'll get to that at some other time (perhaps around New Year's) but suffice to say today that the Windy City Author is enjoying her new life in beautiful southern coastal Maine. I love my new home and wonderful neighbors but, of course, I also miss Illinois. How can I not? I lived there for well over a century!
The new challenge for me will be to determine how the Windy City Author is going to transition into a writer who incorporates a new regional flair into her work. New England has a rich history of outstanding writers in all genre including my own own and I'm excited that I am now able to tap into that rich tradition and, hopefully, bring something to the table as well. As I feel myself evolving as a novelist I realize how much my Midwestern roots shape and influence my story telling. It is so exciting to think about the many possible ways in which my new home will add it's own unique flavors to the body of my work.
Lobster meat on a Chicago pizza? Who knew?
I haven't blogged here since I shut it down to start packing for our move late last summer but despite my absence here I've done a great deal of writing elsewhere (as you may know, I write a LOT of political commentary!). However, one of the projects I've been working on is the sequel to January Moon, March Storm, which I hope will be ready to publish in early to mid '12. Like all writers, there is almost nothing as wonderful as hearing from your fans and I'm not sure what's normal for most writers but I received an enormous amount of earnest heartfelt feedback from my readers. It is really amazing how often people who have read January Moon will contact me either through my website or on Facebook or Twitter and share with me their wonderful impressions and opinions about January Moon. I am not yet a well-known author -- and it is quite possible I never will be -- but I suspect there is no author in America who receives the kinds of messages I am blessed to receive. There are many things about the issues and characters in January Moon that seem to strike very, very deep chords in people, such as racism, female genital mutilation, religious extremism and mental illness but above all else it seems the story of a heroic dog, as well as the healing powers of true love resonate more than any other.
Last week I received a remarkable email from a woman struggling with her own dysfunctional family issues and she wrote this: "Above all else, I think January Moon may be a love story. It shows how tragic it is when we live without love and how magical it is when we are blessed with love. Love, or the lack of it, is really what shapes our lives, isn't it?"
So, on that wonderful note -- and what could be more about the Holiday Season than the Spirit of Love? -- I thought I might share with you today an excerpt from January Moon that specifically mentions Christmas.
In the following excerpt, Chicago Homicide detective, Lt. Del Carter, is spending Christmas with his fiancé, Jess Farrell, at her parents' home in Wisconsin. It is already well established that Del and Jess are deeply in love.
Several days earlier, Del and Jess delivered the heartbreaking news to her parents, Frank & Louise, that their beloved 13-year-old granddaughter, Summer, was dead. Summer, or "Sunny" as she was called, had been a happy and content child who was being lovingly raised by her maternal grandparents until an Illinois court ruled in favor of her mentally unstable biological mother, the Farrells' oldest daughter Evelyn. After the court ruling, Evelyn, a woman with a history of serious emotional problems, took her daughter to live with her inside a secretive and bizarre religious cult somewhere on the Illinois prairie.
The circumstances under which Sunny died are both tragic and mystifying and before the mystery of her death is solved, the cult leaders, the feds, the police, Del and Jess, and even the Mayor of Chicago, will be dragged into one of the strangest tales of mutilation, murder, and terror to ever surface in the Midwest.
However, on this night, a week after Sunny's death, the Farrell's are trying valiantly to just survive Christmas and Del is determined to cover them like a glove. In this part of the story, which I've deliberately constructed to give the reader a breather from the previous tension, Del and the Farrells enjoy a rare moment of peace and Del is given the opportunity to share with Jess and her parents some of his own family’s Christmas traditions.
Excerpt from Chapter 34:
The Farrell’s and Del went to Midnight Mass and Del had to admit Fr. Mike gave a pretty good sermon. Not that he was an expert on sermons, of course, but it reminded him he had to have a serious conversation with Jess about how they were going to raise their kids. He’d been reading Eastern philosophy and had respect for Buddhism but he figured there probably wasn’t a chance in hell that was going to fly with the Farrell’s.
Del and Frank enjoyed some powerful eggnog before they left for church and Del felt warm and mellow and even kind of sappy afterward. He held Jess’s hand and wanted to cry when everyone sang Joy to the World.
He knew Louise, Frank and Jess were dying inside; Jess cried so much people began to look at her strangely and it got kind of embarrassing. When the woman next to Del tapped his arm and kindly handed him more tissues, he whispered, “It’s been kind of tough. There’s been a death in the family.”
“Oh, my,” the poor woman said, “I’m so sorry. Christmas is such a bad time for those things.” She then whispered what she learned to her husband and he nodded kindly at Del, sort of a “hang in there old buddy, keep the chin up” type of look. She then tapped someone on the shoulder in the pew in front of here and whispered some more. Those people turned around and smiled sadly.
The Farrell’s were totally oblivious to the fact that Del was making inroads into the community. By the time the service came to the part where everyone shares the sign of peace most of the church knew the Farrell’s had suffered a terrible tragedy. Louise and Frank were a bit surprised and touched at the number of people who stepped out of pews and walked up and down and across the aisle to hug Louise and shake hands with Frank. Del and Jess received their fair share of Christian love too.
On the ride home, though, Louise had her reservations about how much pain she really wanted to share.
“Well, now I guess I’ll have to tell the whole damn town what happened to us,” Louise bitched. “That nosey cow Lucie Heffernan was all over me as we were leaving Mass. I hate telling her anything. She always twists what she hears and the story’s never the better for it either.”
“Oh, those damn peas,” Frank laughed, “so hard to keep on earth…” Del and Jess laughed but Louise didn’t think it was very funny.
“Frank, sarcasm doesn’t become you.”
Del delivered everyone home safely and proceeded to introduce them to a Carter family post-Midnight Mass tradition: a big breakfast of bacon, eggs and pancakes at 1:30 in the morning. He made a special dish for Wolf and he was in chow hound heaven.
As he was breaking eggs and flipping pancakes, and Jess was minding the bacon, Del educated the Farrells about his own family’s traditions.
“Well, just like you, we always went to Midnight Mass and then returned home to eat bacon and eggs and pancakes, just like we’re doing now. Then we’d all sit around in our pj’s and open presents. When we were really little kids, our next door neighbor came over and played Santa.”
Del had plenty of good stories about Santa.
“Sometimes Bill was stinko drunk. My sister Katie thought Santa was an alcoholic for years and worried about him killing himself on the sled, I guess pile driving Rudolph into a skyscraper or something. Katie was that kind of kid, always thinking about the damnedest things.”
And then there was the time the family dog pissed on Santa’s leg. “Bill bought a new suit that year but for some reason he couldn’t explain the damn thing smelled absolutely terrible. Like rotten venison. He smelled better when he only stunk of cheap gin.”
Del explained how the family would fall into bed, totally exhausted, about 4 or 5 o’clock and wake up to the miraculous smells of turkey and all the trimmings.
He never knew how Marge pulled it off but she did. “My Mom must have stayed up to stuff the bird and start the meal and she probably crawled back to bed to catch an hour or two of sleep and then got up again. But by the time everyone was up and dressed and relatives were showing up at the door about noon, one o’clock, Mom already had the dining room table set with her mother’s dishes, real silver, and crystal and the food ready to take out of the oven.”
Del’s sisters and their families keep the tradition going. “They all go to the folks after Mass and everyone stays the night. We got people all over the place. My nieces and nephews love it. They have their own sleeping bags and they sleep around the tree. Our neighbor Bill still comes over and plays Santa. Only now he really looks like Santa! He doesn’t need rouge on his nice red bulbous nose or any padding!”
Jess laughed, “And you want to be a Buddhist? Yeah right. You love Christmas more than I do. You might not be religious, but you’re a hopeless romantic, babe, and Christmas is full of a special kind of romance.”
“Yeah,” his whispered, “and kids. I want kids. They go well with Christmas. I’m about ready to steal some.”
“Oh damn, I misunderstood. I bought you sax for Christmas. Didn’t you want good sax?”
Frank interrupted, “You want good sox? I’ll tell you where to go. Bass Pro. They got thermal.”
“Have some more eggnog Frank.”
“Good idea. Thanks!”

domain: literature


text:
ABOUT THE CLUB AND MEMBERSHIP
The "Club 4000" was established in 1993 from Luciano Ratto e Franco Bianco in order to constitute a reference point and meeting place for all collectors of peaks higher than 4000 m, useful for the exchange of information, documentation and experiences on 4000 of the Alps (see. "Brief History of the Club 4000").
Currently the Club 4000 is a group of Turin Section of the Italian Alpine Club, according to a precise regulation. More information can be had from circular sent to members and communique He appeared in the Journal of CAI Torino "Mountains and Valleys".
To join this Club you must have risen at least 30 peaks (originally 50 ...) of 82 appear under 'official list acknowledged UIAA
The membership application must contain the following data:
- Name and surname;
- Date of birth;
- E n. phone;
- E-mail address, if available (if you do not want to appear on the Web site, explicitly request);
- List of 4000 risen among those listed in 'Official list approved by UIAA, Giving the date, the ascent route and possibly the name of the climbing companions;
- Date of last 4000 rose for the first time;
- Possible notes; Any submission by the other Club 4000 member or a CAAI member or the President of the CAI Section of belonging.
The application for membership implies the acceptance that the supplied data are published on the website of the Club 4000.

domain: geography


text:
Sunday, 1 April 2012
Sweating the Small Stuff?
I almost can't believe that such a storm in a teacup has been stirred up this week in our local press over Hot Cross Buns. Apparently, a batch has appeared in one of our most respected supermarkets, labelled "Halaal" and this has released a tide of resentment amongst a (hopefully) small number of those whose Christian sensitivities have been extremely offended. So much bad feeling has been caused that the supermarket involved has withdrawn all the buns from their shelves. So now no-one gets any. Surely this is cutting off one's nose to spite one's face? The sad thing is that this episode reveals just how paranoid and religiously intolerant our society is just below the surface. We pretend as best we can that we are wonderful and accepting of those whose beliefs happen to differ from our own - and then this sort of thing tears through the flimsy facade. Perhaps its another wake-up call. Personally, I eat anything I fancy regardless of labelling, except that I try to avoid too many preservatives. Just so as you know! Happy Easter to my lot! Happy Holidays to everyone else!

domain: sociology


text:
End-users continue to watch the time tick by on the countdown clock to the implementation of various aspects of Dodd-Frank while still awaiting clarity on a couple of critical – and costly – regulatory burdens which currently seem poised to impact them. In an ongoing effort to help find that clarity, the NAM has been working diligently as a leading member of the Coalition for Derivatives End-Users on both the hill and before the regulatory bodies implementing the law. Today we hope marked a positive step forward in the House Agriculture Committee’s hearing, “Examining Legislative Improvements to Title VII of the Dodd-Frank Act,” which featured testimony by NAM member and Honeywell International Assistant Treasurer Jim Colby. Colby testified on behalf of Honeywell and the Coalition — in support of coalition-backed legislation H.R. 634, which would provide a clear exemption from margin requirements for non-financial end-users as was the original intent of Congress.
The NAM has long advocated for this legislative fix and has worked longside the Coalition at the regulatory bodies urging that the rules promulgated under Dodd-Frank include this exemption. During the last Congress, the same legislation cleared the House overwhelmingly with over 370 votes in favor and withered in the Senate despite bipartisan support. We’re hopeful that today’s hearing and Ag Chairman Lucas’ indication that the Committee will soon move to mark up the bills included in the hearing will result in quick action that will allow the bill to be considered by the House Financial Services Committee and by the full House of Representatives in the near term.
The hearing also featured testimony in support of another NAM and Coalition endorsed bill, H.R. 677 which would exempt inter-affiliate and centralized hedging center unit swaps from clearing and other regulatory requirements intended for market-facing swaps. This legislation also clarifies a provision in Dodd-Frank that failed to distinguish internal risk management techniques in the form of inter-affiliate swaps from external market facing swaps. Many companies today use centralized hedging centers or centralized treasury units as a risk management tool – one that is often considered a best-practice. Under Dodd-Frank it this structure wasn’t contemplated and today without a change, the internal swaps a company does between these centers and their own affiliates would be subject to the same costly reporting and clearing requirements as external swaps with a swap dealers or a major swap participant. Further, the bill ensures that non-financial end-users who utilize these centralized hedging centers are allowed to use the end-user clearing exemption. Without this clarification, these centralized hedging and treasury centers wouldn’t qualify for the end-user clearing exemption because they would be deemed financial entities since their primary function is to engage in financial transactions for the corporate parent.
We are pleased that the committee also considered H.R. 677 today and hope that it too will be marked up and ready for review by the House Financial Services Committee and the full House in the near-term. A predecessor of this bill moved in tandem with a margin bill last year and also passed the House with over 350 votes. We hope to see that replicated soon.
So, while the clock ticks, hopefully today’s hearing is the first steps towards fixing these two burdensome problems casting a shadow over sound risk management practices employed by end-users.
In her role, Carolyn leads the Institute’s workforce efforts to close the skills gap and inspire all Americans to enter the U.S. manufacturing workforce, focusing on women, youth, and veterans. Carolyn steers the Institute’s initiatives and programs to educate the public on manufacturing careers, improve the quality of manufacturing education, engage, develop and retain key members of the workforce, and identify and document best practices. In addition, Carolyn drives the agenda for the Center for Manufacturing Research, which partners with leading consulting firms in the country. The Institute studies the critical issues facing manufacturing and then applies that research to develop and identify solutions that are implemented by companies, schools, governments, and organizations across the country.
Prior to joining the Institute, Carolyn was Senior Director of Tax Policy at the NAM beginning in 2011, where she was responsible for key portions of the NAM’s tax portfolio representing the manufacturing community on Capitol Hill and in the business community and working closely with the NAM membership. She served as the Director of Legislative and Government Affairs at the Telecommunications Industry Association, Manager of State and Federal Government Affairs for 3M Company, and in various positions on Capitol Hill including as Legislative Director for former U.S. Senator Olympia Snowe (R-ME), and as a senior legislative staff member for former U.S. Rep. Sue Kelly (R-NY).
Carolyn is a graduate of Gettysburg College in Gettysburg, Pennsylvania graduating with a B.A. in Political Science. She resides in Northern Virginia with her husband and three children.
Latest posts by Carolyn Lee (see all)
- Throwback Thursday: Twin Cities Manufacturers Come Together to Promote Women in Manufacturing - February 28, 2018
- 2017 Manufacturing Day Moments - November 30, 2017
- STEPping Up to Advance Women in the Workforce - October 24, 2017

domain: law


text:
Cultural singer, Mani Martin has dropped yet a new single. Akagezi ka Mushoroza which loosely translates to River Mushoroza speaks of life before the technology era.
Mani pours out his childhood experiences in the song, while he crossed the Mushoroza River in his village to the city.
“The song narrates any village child’s memories,” says Mani Martin.
The song’s video will come soon.
Mani Martin is a famous Rwandan singer, he boasts of Amohoro, my destiny and many other songs.
Share and Enjoy

domain: artistic


text:
Wood Condiment Server Bowls with Braided Base by Nambé
Combining the rustic appeal of acacia wood with the sparkling luster of chrome, these Condiment Bowls will enhance any tablescape. The braided base adds sleek, playful texture to the modern design. Use it to serve sauces, nuts or olives at your next dinner party.
- Acacia wood with chrome plated handles
- Hand wash; dry immediately
- Each bowl holds 12 oz
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text:
Mondo Media, a digital entertainment provider, secured more than $17 million in its third round of equity financing. The round, led by SBVC with supporting investment for global expansion from Venturepark, also included returning investors Foundation Capital, Sofinnova Ventures and Red Rock Ventures. Concurrently, Carl Rosendahl, principal managing director-SBVC, joined MondoMedia's board. The investment will drive Mondo Media's continued expansion of its digital entertainment distribution network, including its syndication relationships with Web sites including WB's Entertaindom, [email protected]
, iWon.com, Terra Lycos, Real Networks, shockwave.com and Netscape Communications' Netcenter. The funds also will be used to fuel network growth in Europe, and to bolster Mondo Media's portfolio of digital entertainment content.Currently Mondo Media syndicates more than a dozen weekly Mondo Mini Shows.
Copyright January 2001, Crain Communications Inc.


text:
Mikey Rocks debuts “Pull Up”, the first single from his next album Populair, with an icey new video. Spotted: Complex Related: Sir Michael Rocks Talks Solo Identity, Banco, and Favorite Miami Strip Clubs (Q & A) Previously: Michael Christmas ft. Sir Michael Rocks – Bootleg DesignerThe Source Article test
Tag Archives | music videotesta
As it turns out, those screengrabs from that Waka “sex tape” which were floating around yesterday were actually an April Fool’s day prank and some preliminary viral marketing for this new collaboration between Flacka and the Pornhub tube site. The new track “Bust” was produced by Mayhem and Mr. Collipark and this video is not safe […]The Source Article test
Kendrick Lamar delivers the first video from his new album To Pimp A Butterfly, which is now the #1 album in the country two weeks running. Shot on location in sunny Compton, CA.
Previously: Kendrick lamar talks #TPAB, Spits Unreleased Verse (Video)
NYMLo returns with a new video for “Almighty LO”, his solo joint from the RFC crew’s tape The Outsiders. Previously: Smoke DZA, NYMLo & Al-Doe – Say Less (Video)The Source Article test
Young Thug releases his new single “Check”, which is the first offering from his upcoming album Carter 6. Previously: Young Thug – I Swear To GodThe Source Article test

domain: entertainment


text:
Justin Timberlake & Jessica Biel Surprise The World With The FIRST Picture Of Their Adorable Baby Boy! How Cute!!
Get Your First Look At Taylor Swift's Academy Of Country Music Awards Look HERE!
Bruce Jenner Expresses Worry Over Hurting His Family In The Latest Promo Clip For His Diane Sawyer Interview -- Watch The Emotional Moment HERE!
Reese Witherspoon & Sofia Vergara Are In Hot Pursuit Of Standout Style At The ACM Awards! See Their Sexy Looks HERE!
Blake Lively Vs. Jessie James Decker's Skintight Pregnancy Style: Who Wore It Better???
Jessie James Decker & Eric Decker Reveal They're Expecting A Baby Boy Right Before The ACM Awards! See The Red Carpet Baby Bump HERE!
Jamie Lynn Spears & Husband Jamie Watson Are Shoo-Ins For Best Dressed At The Academy Of Country Music Awards!
Bobby Brown Says That Bobbi Kristina Is 'Awake' -- Has The 22-Year-Old Really Awoken From Her Coma??
Kourtney Kardashian Celebrated Her Birthday In Vegas Without A Sister In Sight! Where Was Bestie Khloe Kardashian??
Kylie Jenner's Latest Coachella Look Is Giving Catwoman Vibes - But Even Catwoman's Eyes Would Be Popping At This See-Through Suit!
ACM Awards Fashion: Relive Last Year's Best AND Worst Dressed Looks HERE!
Listen To This: Under Them
Beyonce Shows Us What Jay Z Wakes Up To In This Sexy Vacation Video!
Happy 36th Birthday, Kourtney Kardashian! Check Out The Sweet B-Day Messages To Kourt HERE!
Worst Dressed Celebs Of The Week!
Best Dressed Celebs Of The Week!
Listen To This: Closer!
Perez Reviews: An American In Paris
These New Kylie Jenner Coachella Bikini Photos Will Make Your Jaw Drop!
Cameron Crowe Made A Joke About Bruce Jenner's Gender Transition In Another Leaked Sony Email!
Andy Cohen Sends His Support And Best Wishes To Kim Richards Following Her Arrest
Kim Richards Wants To Delay Rehab For Her Daughter's SECOND Wedding?!
Zayn Malik Shaved His Head -- Debuts New Post-One Direction Look At The 2015 British Asian Awards!
Michael Bublé Responds To Booty Photo Backlash! Do You Accept His Semi-Apology?
5 Times We Almost Saw Kendall Jenner's Nipples During Her GQ Shoot!
EXCLUSIVE! Rock Festival-Ready Tresses Through Coachella Weekend With These Easy Tutorials From Celeb Hairstylist Charles Baker Strahan!
Sofia Vergara & Joe Manganiello Share A Steamy Kiss In Front Of A Large Audience! Their PDA Display Is HOT!
Fit Pregnant Mom Gave Birth -- And You Won't BELIEVE How Big Her Baby Is! See The Adorable First Pics HERE!
People Are Pissed At Michael Bublé For Uploading A Picture Of This Woman's Butt! Read The Reactions HERE!
Selena Gomez Shuts Down Body Shaming Critics With ANOTHER Bathing Suit Shot -- Read Her Body Positive Message For Haters HERE!
Kylie Jenner Confesses To Never Really Wearing Makeup - Seriously?! But When She Does, It Takes An Insane Amount Of Time To Put On!
Listen To This: Just Another Heartache
Isla Fisher & Sacha Baron Cohen: Their New Baby's Name Has Been Revealed!!
Plus-Size Fashion Blogger's Swimsuit Photo Goes Viral For Its Inspiring Message!
Kim Richards' Real Housewives Costars Respond To Her Shocking Arrest!
Real Housewives Of Beverly Hills' Kim Richards Arrested! And Alcohol May Be To Blame!
Kendall Jenner Attempts To Shut Down Any Talk About Bruce Jenner's Reported Transition In Her GQ Interview, But Her Reactions Say It All
Ick! Georgia Mom Hosts 'Naked Twister' Sex Party With Her Underage Daughter -- But It Gets WAY Worse!! Read The Report HERE!
Rihanna Gets Political In Her American Oxygen Video! Watch The R8 Summit HERE!
EXCLUSIVE! Paris Hilton Wants You To Get High Off My Love! Check Out The Sexy Teaser Clip HERE!
And there's no stopping her now! Over the weekend, Lady Gaga became the first artist in YouTube history to reach a BILLION views on the website! Between … Read more…
YAYYY! Congrats GAGA!!!!
sorry y'all - i accidentally contributed a little over a year ago…………
Proud? Ew. Stop acting like you created her, like you own her. She isn't your "wifey". She owes you nothing!!! She probably doesn't even like you that much. It's so annoying.
Her 15 minutes is up! Her face is so offensive I can't look at it anymore. Please go away.
YAY!!! Get it girl!!!
youtube views don't count for shit
a video of a baby biting his brother's finger got more than 500 million views..
Very STYLISH of you GaGa……
Re: CaliCoyote – wow, you still think she is only up for 15 minutes of fame…how lame –'
fyi…she is really dominating the world. while you never done anything in your life, other than criticizing talented artists, this 24 years old phenomenon achieved, in 2 years, what others take a lifetime to do…like it or not, she is here to stay. and Pop culture, and every legend of it, are very proud of her! (”')^.^(”')
you go Gaga!!!
proud of what? youtube has like 4 years.so what?gaga would havee no chance if youtube was created in the 80s or 90s. its normal. so what?? and her kids fan stay on youtube all day. gaga sucks dear. even bieber reach that mark.so what??make them good?hell to the no
the only records gaga breaks are the most stupid and the records that noone cares about
So basically her fanbase has been hitting the refresh button and/or programmed a tool to do this for them….
Yeah, well, people stop to look at car crashes and train wrecks all the time.
OMG she is beyond ugly. WTF? Her face is so nasty and those teeth eww! And Maro dares pick on other's looks? Give me a fucking break! She wears idiotic shit because she is so damn ugly that she could never make it as a pop star without stupid outfits. She is also full of shit pretending that she is so so deep and has deep reasons for dressing like an asshole.
IF YOU'D RAISE YOUR HEAD FROM HER MANLY CROTCH FOR A FEW MINUTES YOU'D SEE WHAT A JERK YOU ARE. SHE PROBABLY HATES YOUR GUTS LIKE EVERYONE ELSE WHO HAS KNOWN YOU FOR A WHILE DOES.
LMAO are u kidding me? Jackson the King of entertainment has been the King of Internet since a long time with over a billion views
Of course, none of her followers have jobs, which is why they can sit behind the computer and watch her videos on YouTube all day, every day. Losers!
She only dominates people that don't know what music is…the rest of us could care less.
Does anyone else think dubbing her fans 'little monsters' is incredibly condescending and/or megalomaniacal of her? If I were a Gaga fan, I'd be really put off by that.
stupidity and lack of taste have nothing to do with world domination. epic fail.
THAT'S KIND OF UNFAIR!!!!
RIHANNA WOULD HAVE CLOSE TO 1 BILLION VIEWS BUT WHEN YOUTUBE SWITCHED TO VEVO, ALL HER VIDEOS HAD TO START FROM SCRATCH!!!!!!!!!!!!!!!!!!!!!!!!!!!
THAT FUKING SUCKS……I THINK SHES BETWEEN 500-600 MILLION NOW
RUDE BOY 107 MILLION
DSTM 126 MILLION
LTWYL 150 MILLION
AND HER COUNTLESS OTHER VIDEOS
LOL she looks like the white yoko ono its like holloween year around with this bitch. Why cant she just seperate lady gaga from stephani and wear a pair of jeans and a t-shirt or a pair of shorts and a tang top something other then holloween costumes. And no one cares about youtube views any one can have the most veiw all you have to do is get a bunch idiots with no jobs sit around and hit replay.
wtf she is NOT ugly. our perception of beauty is so flawed we think anyone who is not plastic and airbrushed is ugly and it's sick. Gaga is beautiful and congrats on the 1 billion views!!
Get your FUCKING head out of her ASS. She is an IDIOT. Fine she can sing and play piano. Big fucking deal.
Re: bowlerderby – Slipknot call their fans 'maggots'. It basically means that the fans feed off there music. Lady Gaga is the Fame Monster. She is the Mama monster and her fans are her little followers/children i.e Little Monsters. I'd rather be called a monster than a maggot
ONE billion views and she doesn't get one stinkin penny! I bet she is THRILLED! Every artist's dream. NO money from all those hits for her to buy coke and snort up her over sized Guidette nostrils. PS, still w/the 'wifey' thing, huh? I throw up in my mouth a little every time I see that. I bet she laughs at you behind your ugly back. In my best Piper Laurie voice, "they're all going to laugh at YOU!!!"
1 Billion people are dumbasses. And really who gives a damn about 1 billion views on youtube I bet it was her fans watching it over and over. Who gives a fuck about youtube views… moving on…
Wow!!! Congrats Lady Gaga it's not like Perez helped you cheat by asking his readers to click on a link that directs them to your videos. Just sayin!!!!
You do know that its not 1 billion people indvidually. Let her have a #1 release and beat MJs record for the biggest single album of all time, then I'll care
She's in it for the long haul. Writes all her music, loves people, saves her craziness for her clothes rather than personal break downs, and most importantly is entertaining. That's what entertainers are for, to entertain us.
I feel bad that I ever watched any of her videos on youtube now. She is a devil worshipper and a illuminati. So she is looking for world domination
Honestly guys there is nothing special about her songs. The only song I like of hers is Alejandro. The rest arent that special. I think what makes her famous is the halloween costumes she wears everyday. People like the fact that she has a really unique sense of style.
Re: nicklerob22 – How is that unfair all the artists started fresh and Gaga came out on top
All this means is that her videos were clicke don 100 times. Meaning, one person who loves her so much (like you, possibly) could have watched the videos hundreds of times. Also means that someone could have clicked on it, and not watched the whole video. So it's a good accomplishment, but not amazing. It's not like 1 billion separate people watched her videos. That would be amazing.
Re: Mushu Baby – oh please you don't believe that illuminati bullshit, do you?
just c'mon people don't be that stupid, she is trying to make music. if you don't like her stfu and go away.. bitch plz.
wow she is so fricking overated,her voice is average and computerized,she loves gays so she sells albums….
mj is the king if music,he can sing dance give to charity and was an amazing man,she isnt shit on mike
A lot of other musicians would've reached that before her if it wasn't for the fact that their record labels keep removing videos because their uploaded by a fan or they've blocked them for those of us outside the US.
LADY GAGA IS AMAZING
Please tell Gaga to speak proper English please. We reached not reach learn your tenses.
Re: MadonnaLive – "There's something ultimately boring about criticism that insists that the glories of the past were so great that nothing modern can ever match them." I think that this sentence describes you very well
Re: LizardKinG – then…what are you doing here???
She is one hideous man. Look at those beaver teeth. There's no straight man who I have ever heard who has found him attractive.
Re: LizardKinG – agreed.
Re: LaBamba18 – um you make no fucking sense you fucking idiot.
Re: MadonnaLive – well actually fuckface… Madonna, MJ, and all the greats have been on Youtube longer than Gaga. ALSO… there have been manyyyy Music videos and nobody has had more views than her
Re: fabulicious-frankie – Anyone who names their fans is a douchebag.
while looking like a tranny.
What the fuck is that thing? It's not Halloween yet is it?
Re: MadonnaLive – YOU ARE OBSESSED. bitch gtfo out of gaga's posts if you despise her so much. You are PATHETIC.
BRAG BRAG BRAG! Someone need to shut her and Mario up.
Stop the presses!!
Justin Timberlake and Jessica Biel's baby has made his first appearance on social media, and Silas Randall Timberlake is just the cutest darn thing EVER!
In all honesty though, we're a bit shocked!
[ Related: Justin Timberlake Loves Cooking For His Pregnant Wife! ]
The couple are both pretty much known for keeping their family life private, so this is definitely a big deal!
Justin shared the photo on Sunday and captioned it:
[Image via Justin Timberlake/Instagram.]
Dierks Bentley & His Wife Cassidy Black Perfectly Match On The Academy Of Country Music Awards Red Carpet!
Kim Richards' Arrest Might Leave Her Cut From Real Housewives Of Beverly Hills! Hear About The Rumored Debate Going On At Bravo HERE!
Miley Cyrus Goes From Prim & Proper To Pasties & Armpit Hair While Inducting Joan Jett Into The Rock And Roll Hall Of Fame!
Zayn Malik Gives A Heartwarming Speech About The Boys Of One Direction At The British Asian Awards! Does The Singer Feel Regret Over Leaving The Band?
These Celebrity Moms Were Posting Breastfeeding Photos Before Instagram's Policy Change!
Execs Talk 'Odd Bird' Bradley Cooper And Costar Emma Stone In More Leaked Sony Emails!
Worst Coachella Looks Of All Time!
Coachella 2015: All The Fashion From The Festival!
14 Celebrities Who Have Broken Up Relationships & Marriages!
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domain: celebrity


text:
20 Stems | 14" Royal Blue Artificial Poly Foam Calla Lily Flowers
Item Number :ARTI_LILY001_ROY
|Quantity: 20 Stems Artificial Calla Lily|
|Spadix Color (Flowers Middle): Yellow|
- Spadix Material: Plastic
- Stem Thickness: 1 cm
- Uses: Wedding, Party, Event, Banquet, Decoration
I'm going to make bouquets for my daughter wedding in Nov 2022. They feel so real like and excited to get them together.
Love these flowers. They are made with a vegan suede like fabric that makes them feel real. Because they are shipped in a box, some were flat. I just rolled them over for a few hours and "presto", they were like full bloomed lillies. Definitely ordering more!
These are beautiful, they look so real.
My experience was great
Just what I wanted for way less!
They look and feel great just as pictured would definitely purchase again from this company!
Everything was wonderful
Use for wedding
It was easy to purchase and they looked realistic
I love them. Totally perfect for my vase

domain: hobby


text:
Edited by Jonathan Falwell
Contributions by Charles Billingsley Ergun Caner
Format: Paperback / softback
Innovatechurch by Jonathan Falwell
Book DescriptionBased on a new ministry conference and Web initiative of the same name, "innovatechurch "gathers expert advice from a who's-who of next generation church leaders keenly determined to uphold never-changing truth in anever-changing world.These eight esteemed contributors write two chapters each about their field of expertise and passion, providing readers with fresh methods for growing and leading the church without compromise. They include Jonathan Falwell (Leadership), Charles Billingsley (Worship), Daniel Henderson (Prayer), Rod Dempsey (Discipleship), Mat Staver (Culture), Dave Earley (Church Planting), David Wheeler (Outreach), and Ergun Caner (Apologetics).Pastors, church leaders, professors, and seminary students will be anxious to learn from and frequently reference these innovative, insightful presentations.
Buy Innovatechurch book by Jonathan Falwell from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780805448269
Classification: Christian leaders & leadership
Format: Paperback / softback (213mm x 137mm x 23mm)
Imprint: Broadman & Holman Publishers
Publisher: Broadman & Holman Publishers
Country of Publication: United States
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Author Biography - Jonathan Falwell
Jonathan Falwell is senior pastor of Thomas Road Baptist Church in Lynchburg, Virginia, founded by his late father, Dr. Jerry Falwell. He is also executive vice president of Spiritual Affairs at Liberty University where he earned a Bachelor of Science degree. Jonathan also holds degrees from Liberty Baptist Theological Seminary (Master of Arts in Religion) and William Howard Taft University (Juris Doctor). He and his wife have four children.
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text:
Jerusalem: England! awake! awake! awake!
William Blake, Jerusalem (1804).
2 Jerusalem thy Sister calls!
3Why wilt thou sleep the sleep of death
4 And close her from thy ancient walls?
5Thy hills and valleys felt her feet
6 Gently upon their bosoms move:
7Thy gates beheld sweet Zion's ways:
8 Then was a time of joy and love.
9And now the time returns again:
10 Our souls exult, and London's towers
11Receive the Lamb of God to dwell
12 In England's green and pleasant bowers.
1] First engraved by Blake in or shortly after 1818, although it bears the date 1804 on its title-page. It is in four parts and comprises one hundred plates. Six copies survive, one in colour. The first extract is from Plate 15 in the first part; the second is from the introduction to the fourth part, Plate 77. Back to Line
Publication Start Year:
ca. 1818 (the stated date of printing notwithstanding)
RPO poem Editors:

domain: library


text:
Readers will no doubt be aware that Ms Tara Davison has continued on here attempts to follow me around and close down my websites etc.
She has threatened the source of my Pandora's Box information with legal action Namely Gordon Bowden) but for obvious reasons this has not happened.
I guess its a case of why take such a matter as massive fraud to court when is is likely that the findings were in actual fact correct.
Gordon has asked many of the fraudster he reveals to bring it before the courts but all, repeat all, have not continued with their actions.....thus I rest my case.
I have intentionally left up Pandora's Box Part 4 which it would appear touched a few raw nerves for Ms Davison.......now it is time to move forward and reveal more grime and slime in the Pandora Box series.
As I have already inserted all articles up to and including Part 6 I will now start on 7, 8 9, and the final Part 10. The last part I am sure will again cause the hairs on the back of Ms Davison neck to stand up, for obvious reasons.
So thank you for being patient and enjoy more hard hitting news and information.


text:
Spencer Jones made five 3-pointers as part of a 25-point effort to help Stanford post an 83-60 victory over Oregon State in Pac-12 play on Thursday night in Corvallis, Ore.
Brandon Angel added 15 points on 6-of-7 shooting as the Cardinal (13-17, 7-12 Pac-12) won their second straight game. Max Raynaud scored 13 points and Harrison Ingram added 11 points and eight rebounds.
Jordan Pope and Tyler Bilodeau scored 11 points apiece for Oregon State (10-20, 4-15), which lost for the fourth straight contest and 14th in the past 17.
Stanford shot a stellar 58.8 percent and also was hot from 3-point range, connecting on 12 of 21 for a 57.1 percent clip. The Cardinal are 24 of 45 (53.3 percent) from 3-point range over the past two games.
The Beavers shot 35.8 percent and were just 21.7 percent (5 of 23) from behind the arc.
Stanford held a 21-11 edge in points off turnovers. Oregon State committed 11 and the Cardinal had seven. Stanford had 23 assists on 30 made baskets.
Angel and Spencer Jones buried 3-pointers during an 8-0 run to start the second half, giving the Cardinal a 48-34 lead.
Later in the half, Ingram scored back-to-back baskets and Spencer Jones added a trey as Stanford increased the advantage to 59-41 with 12:04 left.
Ingram made two free throws to push the lead to 20 at 63-43 with 11:01 left. The lead topped out at 28 points.
Spencer Jones scored 15 first-half points to help Stanford hold a 40-34 lead at the break.
Oregon State started strong and led 14-5 just 5 1/2 minutes into the game. But Michael Jones and Spencer Jones knocked down 3-pointers to end a 10-0 spurt as Stanford took a one-point edge with 10:42 left in the half.
The Beavers later led 31-29 after Bilodeau’s basket with 3:43 left. However, Spencer Jones scored seven points during a 11-0 run that gave the Cardinal a nine-point lead. Pope was fouled while shooting from long range with 0.6 seconds left, and he made all three free throws to bring Oregon State within six.
–Field Level Media


text:
Researchers claim that using several very thin layers of ferroelectric crystals can lead to significantly better ferroelectric solar cell efficiency. But don’t pull the panels off your roof yet. Conventional cells are still much more efficient than ferroelectric devices — at least, for now.
Unlike conventional silicon-based solar cells, ferroelectric cells don’t depend on a PN junction and — in theory — can be cheaper and easier to produce. However, they typically don’t absorb as much sunlight as other materials.
Barium titanate alone exhibits some electric current when exposed to sunlight, but it isn’t nearly as efficient as modern silicon solar cells. However, when the researchers produced a 200 nanometer-thick film “sandwich” made of barium titanate in between layers of strontium titanate and calcium titanate, the output current went up by a large factor. The resulting cells are still not up to par with commercial silicon cells, but they are a lot closer.
The work was done at Martin Luther University Halle-Wittenberg, a German institution. If you do a search, they seem to do a lot with ferroelectric materials like barium titanate.


text:
Keep Art Alive :: “Leaf Hat” :: Art by Kelly Vivanco
And one day she just woke up
Once upon a time there was a girl who found herself in
a huge and overwhelming world she wasn’t ready for.
This girl had lived her young life hiding in books,
school and her imagination.
She had many secrets and pain hidden deep inside her pale,
almost translucent skin,
and she walked about with a very thin veil of trust,
for anyone who tried to peak beneath the surface
of her quiet smile.
She thought she could change the person she had been.
For as long as she could remember taking breath,
she had tried on many disguises,
and filled herself with poisons that would temporarily mask the wounds she held too deep.
She opened herself up to strangers,
and they offered her candy and liberties,
and, more pain.
Than one day she met a boy painted with vibrant colors and glittery wings.
He too was hiding behind a costumed happiness.
He too was trying to evolve into something brighter and different.
The girl and this boy began a strange friendship that seemed to
transcend both the outer and inner selves they were alone.
One night a kiss awoke the two sleeping souls,
and they began a dance of healing and bliss.
The girl slowly opened up her boxes and trinkets.
She laid them out in front of the boy and he held them gently,
listening to their whispered tales.
He left tiny kisses all over them and very slowly the cracks were
covered over with translucent light.
He brought to her similar tales and scratched up jewels which she took
in her arms and made beautiful,
shining and rare.
Too soon these healing children were separated by
truths and lies, and the outside world.
They tried to fly back into each other’s realms occasionally,
and were always re-greeted by music.
But, after a while the melodies waned and began to lose their rhythm.
The boy’s wings grew brittle and broke off,
and the girl took her trinkets and shoved them down deeper than
The boy went off into unknown skies,
taking on feathers in exchange for the wings he had left behind.
The girl tried to tie on his wing,
but they slipped and fell into the mud.
She ended up wrapping them up in a silver lined blanket and putting
them away under her bed at her childhood home.
Back to where dreams were spun,
and her story had started.
Her life took strange turns after that.
Some of them full of wonder and glory,
others plagued by ghosts and sorrow.
She caught glimpses of the boy’s life,
but they always came as blurred snapshots that were hard
to make out.
She tried to forget the colors they spun together,
hand in hand,
and she took out new brushes to paint herself a future;
a silver band wrapping itself tightly over a new revelation.
Someday later the boy’s name crossed her path again
and she called to him in a quiet voice full of trepidation.
Just hearing her name spoken from his lips made her suddenly remember,
spinning in circles and the feel of sand between her feet.
She felt the tickle of fins where her toes should be,
and heard the call of the waves.
So, she silently traversed back to the house of her beginning,
shoving her adult body underneath her little girl bed of long ago.
There she found the set of wings still intact,
albeit dusty and much older.
She sits with them now at the edge of the shore
and wonders how he will look when she hands them back to him.
She asks herself if he will even remember.
Landed (live) :: Ben Lee


text:
Structure, Volume 14, Issue 3, 1 March 2006, Pages 611-621
Chad A. Brautigam, R. Max Wynn, Jacinta L. Chuang, Mischa Machius, Diana R. Tomchick and David T. Chuang
The 9.5 MDa human pyruvate dehydrogenase complex (PDC) utilizes the specific dihydrolipoamide dehydrogenase (E3) binding protein (E3BP) to tether the essential E3 component to the 60-meric core of the complex. Here, we report crystal structures of the binding domain (E3BD) of human E3BP alone and in complex with human E3 at 1.6 Å and 2.2 Å, respectively. The latter structure shows that residues from E3BD contact E3 across its 2-fold axis, resulting in one E3BD binding site on the E3 homodimer. Negligible conformational changes occur in E3BD upon its high-affinity binding to E3. Modifications of E3BD residues at the center of the E3BD/E3 interface impede E3 binding far more severely than those of residues on the periphery, validating the “hot spot” paradigm for protein interactions. A cluster of disease-causing E3 mutations located near the center of the E3BD/E3 interface prevents the efficient recruitment of these E3 variants by E3BP into the PDC, leading to the dysfunction of the PDC catalytic machine.
Summary | Full Text | PDF (666 kb)
Structure, Volume 15, Issue 8, 14 August 2007, Pages 992-1004
Masato Kato, Jun Li, Jacinta L. Chuang and David T. Chuang
Pyruvate dehydrogenase kinase (PDK) isoforms are molecular switches that downregulate the pyruvate dehydrogenase complex (PDC) by reversible phosphorylation in mitochondria. We have determined structures of human PDK1 or PDK3 bound to the inhibitors AZD7545, dichloroacetate (DCA), and radicicol. We show that the trifluoromethylpropanamide end of AZD7545 projects into the lipoyl-binding pocket of PDK1. This interaction results in inhibition of PDK1 and PDK3 activities by aborting kinase binding to the PDC scaffold. Paradoxically, AZD7545 at saturating concentrations robustly increases scaffold-free PDK3 activity, similar to the inner lipoyl domain. Good DCA density is present in the helix bundle in the N-terminal domain of PDK1. Bound DCA promotes local conformational changes that are communicated to both nucleotide-binding and lipoyl-binding pockets of PDK1, leading to the inactivation of kinase activity. Finally, radicicol inhibits kinase activity by binding directly to the ATP-binding pocket of PDK3, similar to Hsp90 and Topo VI from the same ATPase/kinase superfamily.
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Chemistry & Biology, Volume 11, Issue 1, 1 January 2004, Pages 10-12
Squire J Booker
Lipoic acid is almost universally required for aerobic metabolism. However, the mechanism for its synthesis and incorporation into proteins has remained elusive. A groundbreaking study published in the December issue of Chemistry & Biology[] uncovers critical features of the lipoic acid biosynthetic pathway.
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Copyright © 1997 The American Society of Human Genetics All rights reserved.
The American Journal of Human Genetics, Volume 61, Issue 6, 1318-1326, 1 December 1997
1 Laboratoire de Biochimie Médicale B and Laboratoire d'Expression Génétique et Pathologie du Dévéloppement CNRS, URA1335, Paris
2 Unité de Recherches sur le Mécanisme d'action cellulaire des hormones, INSERM, Unité 30, Paris
3 Laboratoire de Biochimie Pharmacologique et Métabolique, INSERM, Unité 75, IFREM, Institut Necker, Hôpital des Enfants Malades, Paris
We have identified and sequenced a cDNA that encodes an apparent human orthologue of a yeast protein-X component (ScPDX1) of pyruvate dehydrogenase multienzyme complexes. The new human cDNA that has been referred to as “HsPDX1” cDNA was cloned by use of the “database cloning” strategy and had a 1,506-bp open reading frame. The amino acid sequence of the protein encoded by the cDNA was 20% identical with that encoded by the yeast PDX1 gene and 40% identical with that encoded by the lipoate acetyltransferase component of the pyruvate dehydrogenase and included a lipoyl-bearing domain that is conserved in some dehydrogenase enzyme complexes. Northern blot analysis demonstrated that the major HsPDX1 mRNA was 2.5 kb in length and was expressed mainly in human skeletal and cardiac muscles but was also present, at low levels, in other tissues. FISH analysis performed with a P1-derived artifical chromosome (PAC)–containing HsPDX1 gene sublocalized the gene to 11p1.3. Molecular investigation of PDX1 deficiency in four patients with neonatal lactic acidemias revealed mutations 78del85 and 965del59 in a homozygous state, and one other patient had no PDX1 mRNA expression.


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In more severe cases, medications that modulate the immune system (primarily corticosteroids and immunosuppressants) are used to control the disease and prevent recurrence of symptoms (known as flares). Depending on the dosage, people who require steroids may develop Cushing's syndrome, symptoms of which may include obesity, puffy round face, diabetes mellitus, increased appetite, difficulty sleeping and osteoporosis. These may subside if and when the large initial dosage is reduced, but long-term use of even low doses can cause elevated blood pressure and cataracts.
Rates of positive ANA tests are affected by the prevalence of systemic lupus erythematosus in the population. Specifically, false-positive rates will be higher in populations with a low prevalence of the disease, such as primary care patients. Because of the high false-positive rates at 1:40 dilution, ANA titers should be obtained only in patients who meet specific clinical criteria (discussed in the clinical recommendations section of this article). When ANA titers are measured, laboratories should report ANA levels at both 1:40 and 1:160 dilutions and should supply information on the percentage of normal persons who are positive at each dilution.41
The discovery of the LE cell led to further research and this resulted in more definitive tests for lupus. Building on the knowledge that those with SLE had auto-antibodies that would attach themselves to the nuclei of normal cells, causing the immune system to send white blood cells to fight off these "invaders", a test was developed to look for the anti-nuclear antibody (ANA) rather than the LE cell specifically. This ANA test was easier to perform and led not only to a definitive diagnosis of lupus but also many other related diseases. This discovery led to the understanding of what are now known as autoimmune diseases.
Nitrogen in the blood in the form of urea, the metabolic product of the breakdown of amino acids used for energy production. The normal concentration is about 8 to 18 mg/dL. The level of urea in the blood provides a rough estimate of kidney function. Blood urea nitrogen levels may be increased in the presence of dehydration, decreased renal function, upper gastrointestinal bleeding, or treatment with drugs such as steroids or tetracyclines.
The symptoms involved in CREST syndrome are associated with the generalized form of the disease Systemic sclerosis (scleroderma). CREST is an acronym for the clinical features that are seen in a patient with this disease. The “C” stands for calcinosis, where calcium deposits form under the skin on the fingers or other areas of the body. The “R”, stands for Raynaud’s phenomenon, spasm of blood vessels in the fingers or toes in response to cold or stress. The “E” represents esophageal dysmotility, which can cause difficulty in swallowing. The “S” is for sclerodactyly, tightening of the skin causing the fingers to bend. Finally, the letter “T” is for telangiectasia, dilated vessels on the skin of the fingers, face, or inside of the mouth.
The authors reviewed the influence of nutritional factors on systemic lupus erythematosus (SLE) and discussed an alternative treatment option. The autoimmunity and inflammatory process of SLE are related to the presence of dyslipidemia, obesity, systemic arterial hypertension, and metabolic syndrome, which should be properly considered to decrease cardiovascular risk. A diet with moderate protein and energy content, but rich in vitamins, minerals (especially antioxidants), and mono/polyunsaturated fatty acids can promote a beneficial protective effect against tissue damage and suppression of inflammatory activity, in addition to helping the treatment of those comorbidities. Diet therapy is a promising approach and some recommendations may offer a better quality of life to patients with SLE.
There’s no scientific evidence that avoiding red meat will have an effect on lupus. If you have kidney disease, red meat can give you more protein than your kidneys can handle. If you have high cholesterol or high triglyceride levels, red meat can raise these further. On the other hand, if you have inflammation in your body you need more protein than when you’re healthy. So the bottom line is to eat a well-balanced diet. If you’re not sure how much you should be eating, ask your doctor to refer you to a Registered Dietitian for a consultation.
“My message to patients is that we can do an excellent job of managing the condition compared to 20 years ago,” says Roberto Caricchio, MD, the interim section chief of rheumatology at Temple University Hospital in Philadelphia and the director of the Temple Lupus Clinic at the Lewis Katz School of Medicine. With that said, people should never underestimate the serious effects lupus can have, he adds, which is why working with your doctor to manage the condition is so important.
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