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Canada residents can call a provincial poison control center. o not share this medication with others. Atorvastatin (atorlip-10) packaging 10 mg 30 amount in a package.
G/ml and. pg/ml compared with.
What are atorvastatin tablets for Concomitant intake of large quantities of grapefruit juice and atorvastatin is not recommended. The dose of atorvastatin should not exceed a daily dose of 20 mg during co-administration with products containingelbasvir or grazoprevir.
The dose of atorvastatin should not exceed a daily dose of 20 mg during co-administration with products containing letermovir.
McEvoy GK, ed. Bethesda, MD: American Society of Health-System Pharmacists, 2012 p. cyclosporine fibric acid derivatives, antilipemic dosages exceeding 1 g daily of niacin, danazol, amiodarone, diltiazem, or verapamil may be associated with an increased risk of myopathy or rhabdomyolysis.
Drug Information 2012. What are atorvastatin tablets for such combinations are used, lower initial dosages of the drugs should be administered, and titration to higher dosages should be done with caution. Use of certain statins with potent inhibitors of cytochrome P-450 CYP isoenzyme 3A4, immunosuppressants e.
In the placebo group. The proportions of subjects who experienced cardiovascular death were numerically smaller in the atorvastatin calcium tablets 80 mg group 3. The proportions of subjects who experienced non-cardiovascular death were numerically larger in the atorvastatin calcium tablets what are atorvastatin tablets for mg group 5.
in the atorvastatin calcium tablets 80 mg/day group vs. than in the placebo group 4.
If you take LIPITOR, tell your doctor what are atorvastatin tablets for you feel any new muscle pain or weakness. If you get pregnant, stop taking LIPITOR and call your doctor right away.Atorvastatin product names drug:
Subject records were deidentified and what are atorvastatin tablets for study qualified for and was granted a waiver to informed consent. This study was reviewed and approved by Massachusetts General Hospital s Institutional Review Board under protocol number 2008P001583. This study observed and evaluated the impact of a therapeutic substitution program from low-dose atorvastatin to simvastatin on lipid control.
The Massachusetts General Physicians Organization MGPO is a multi-specialty medical group consisting of more than 2000 physicians practicing at a large tertiary urban academic medical center. We hypothesized that patients switching to simvastatin would exhibit lipid control comparable what are atorvastatin tablets for that achieved by equipotent atorvastatin therapy.
For what atorvastatin is used– sam e and celexa.
In vitro inhibition of HMG-CoA reductase by ortho-and parahydroxylated metabolites is equivalent to that of atorvastatin. In animals, the ortho-hydroxy metabolite undergoes further amlodipine compound and 60% of the metabolites of amlodipine are excreted in in bile following hepatic and/or extra-hepatic metabolism; however, the drug does not appear to undergo enterohepatic recirculation.
Based on observations in rats, atorvastatin calcium is likely parahydroxylated derivatives and for what atorvastatin is used beta-oxidation products. Approximately 70% of circulating inhibitory activity for HMG-CoA reductase is attributed to active metabolites.
In vitro studies suggest the importance of atorvastatin metabolism by cytochrome P4503A4, consistent with increased plasma concentrations of atorvastatin for what atorvastatin is used humans following co-administration with erythromycin, a known inhibitor of this isozymesee DRUG INTERACTIONS.
Atorvastatin modestly improves kidney function over time. April 9, 2019. Statins continue to produce vascular benefits in older adults. February ...:
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Low overall, but were higher in the high-dose atorvastatin treatment group 13, years, 40% women; 93. Caucasians, 3. ndividuals with atorvastatin 80 mg and in nine 0.
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My hair started to fall out. Could be bp meds. Now about my head my thought process is fuzzy. Experienced feeling dizzy some times. Last is the itching. NextMy nose would start to run as if someone turned on a switch.
Rare reports of congenital anomalies following intrauterine exposure to HMG-CoA reductase inhibitors have been received. Atherosclerosis is a chronic process, and ordinarily discontinuation of lipid-lowering medicinal products during pregnancy should what are atorvastatin tablets for little impact on the long-term risk associated what are atorvastatin tablets for primary hypercholesterolaemia.
Maternal treatment with atorvastatin may reduce the fetal levels of mevalonate which is a precursor of cholesterol biosynthesis. For these reasons, atorvastatin should not be used in women who are pregnant, trying to become pregnant or suspect they are pregnant.
Studies in animals have shown toxicity to reproduction see section 5. No controlled clinical trials with atorvastatin have been conducted in pregnant women.
|All patients starting therapy with atorvastatin calcium should be advised of the risk of myopathy and told to report promptly any unexplained muscle what are atorvastatin tablets for, tenderness, or weakness particularly if accompanied by malaise or fever or if these muscle signs or symptoms persist after discontinuing atorvastatin calcium. what are atorvastatin tablets for||7311 placebo) patients treated for a mean period of 53 weeks, 5. 55 atorvastatin vs.||Some medicines should not be taken with atorvastatin calcium tablets. Atorvastatin calcium tablets dosing have not been established in children under 10 years of age.|
|Pup body weight was decreased through postnatal day 21 at 100 mg/kg/day, and through postnatal day 91 at 225 mg/kg/day.||Following concomitant use of atorvastatin (80 mg daily for 8 days) and clarithromycin (500 mg twice daily for 9 days) atorvastatin peak plasma concentration and AUC were increased by 5. what are atorvastatin tablets for||What is the action of atorvastatin n vitro, inhibition of HMG-CoA reductase by ortho- and parahydroxylated metabolites is equivalent to that of atorvastatin.|
What is the action of atorvastatin
During such concomitant therapy, the lowest necessary dosage of atorvastatin should be used. The benefits of what is the action of atorvastatin use of atorvastatin and lopinavir/ritonavir should be weighed against the possible risk of myopathy or rhabdomyolysis.
Caution is advised if such concomitant therapy is employed.
Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at hra. ov. Multivitamin daily. ▫ co-enzyme Q 10 daily. ▫ aspirin 81 mg daily. ▫ clopidogrel 75 mg daily.
▫ atorvastatin 40 mg daily. ▫ nitroglycerin 0.4mg SL q5minprn. There was no evidence of a difference in the treatment effect by patient's gender, age, or baseline LDL-C level. A favourable trend was observed regarding the mortality rate 82 deaths in the placebo group vs.
Plasma concentrations of atorvastatin and its active metabolites were lower ratio of atorvastatin concentration: 0. Appropriate clinical monitoring of these patients is recommended.
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Myositis, rhabdomyolysis, cognitive and sleep disorders, or hair loss In such situations, physicians should consider statin discontinuation, try to decrease cardiovascular risk with other available regimens, and consider statin rechallenge after symptoms/biomarker changes resolve. Stone NJ, Robinson J, Lichtenstein AH, et al.
With careful management, health care providers might successfully treat over 90% of the patients previously reporting statin intolerance; however, the problem still exists for the remaining 10% the ones with what are atorvastatin tablets for AEs causing complete intolerance due to intolerable symptoms e.
Atorvastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, ...
Years, and an average LDL-C of 121. Patients were mainly male 81% white 99% with an average age of 61.
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Service procedure, Establishes a therapeutics committee with the authority for research, development, and approval of a preferred drug list. Requires an independent analysis of the PBM program throughout 2002.
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8 1466-1469. doi. Ann Pharmacother.
What is the usual dose for atorvastatin?
The recommended starting dose of LIPTRUZET is 10/10 mg/day or 10/20 mg/day. The dosage range of LIPTRUZET is 10/10 mg/day to 10/80 mg/day.
Can i eat a grapefruit while taking atorvastatin?
Do not get pregnant. If you get pregnant, stop taking atorvastatin calcium tablets right away and call your doctor. Atorvastatin calcium tablets and certain other medicines can interact causing serious side effects.
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You can take Crestor with or without food. Dosages may be as low as 5 mg per day or as high as 20 mg per day.
Is atorvastatin fat soluble?
As an adjunct to correction of other risk factors. What are atorvastatin tablets for dose should be individualised according to baseline LDL-C levels, the goal of therapy, and patient response. Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event see section 5. The patient should be placed on a standard cholesterol-lowering diet before receiving Atorvastatin 20mg Film coated Tablets and should continue on this diet during treatment withAtorvastatin 20mg Film coated Tablets.
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Atorvastatin Calcium Tablets for oral administration Initial U. Approval: 1996Dose range: 10 to 80 mg once daily 2. hese highlights do not include all what is atorvastatin 20 mg tablet used for information needed to use Atorvastatin Calcium Tablets safely and effectively.
Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels 4. See full prescribing information for Atorvastatin Calcium Tablets. Patients requiring large LDL-C reduction 45% may start at 40 mg once daily 2. Pediatric starting dose: 0 mg once daily; maximum recommended dose: 0 mg once daily 2.
Rare: myopathy, myositis, rhabdomyolysis, what are atorvastatin tablets for rupture, tendonopathy, sometimes complicated by rupture. 1/100 rare. very rare. not known cannot be estimated from what are atorvastatin tablets for available data Rare: angioneurotic oedema, dermatitis bullous including erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis.
Common: myalgia, arthralgia, pain in extremity, muscle spasms, joint swelling, back pain.
Safety and efficacy of statin therapy. 2019; doi: 0. 038/s41569-018-0098-5. Nature Reviews Cardiology. Accessed Jan. Adhyaru BB, et al. what is the action of atorvastatin
For what atorvastatin is used These side effects may go away during treatment as your body adjusts to the medicine. Check with your doctor immediately if any of the following side effects occur: puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue Get emergency help immediately for what atorvastatin is used any of the following symptoms of overdose occur: dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position Some side effects may occur that usually do not need medical attention.
-fold higher atorvastatin exposure AUC than in individuals without this genotype variant c. 21TT A genetically impaired hepatic uptake of atorvastatin is also possible in these patients. Polymorphism in the gene encoding OATP1B1 SLCO1B1 c. 21CC is associated with a 2. In patients with SLCO1B1 polymorphism there is what is atorvastatin 20 mg tablet used for risk of increased exposure of atorvastatin, which may lead to an increased risk of rhabdomyolysis see section 4.
For what atorvastatin is used 4 mmol/l 160 mg/dl and TG 6. years. mmol/l 251 mg/dl All patients had at least 3 of the pre-defined cardiovascular risk factors: male gender, age 55 years, smoking, diabetes, history of CHD in a first-degree for what atorvastatin is used, TC: DL-C 6, peripheral vascular disease, left ventricular hypertrophy, prior cerebrovascular event, specific ECG abnormality, proteinuria/albuminuria. The absolute and relative risk reduction effect of atorvastatin was as follows: 1Based on difference in crude events rates occurring over a median follow-up of 3.
Not all included patients were estimated to have a high risk for a first cardiovascular event. The effect for what atorvastatin is used atorvastatin on fatal and non-fatal cardiovascular disease was also assessed in a randomized, double-blind, multicenter, placebo-controlled trial, the Collaborative Atorvastatin Diabetes Study CARDS in patients with type 2 diabetes, 40-75 years of age, without prior history of cardiovascular disease, and with LDL-C 4.
N Engl J Med. Epub 2008 Nov 9. JUPITER Study Group.

domain: medical


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domain: economics


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When you're a kid, opening your lunchbox in eager anticipation to find whatever delicious snack mom has packed in today was the best part of school break.
Finding the balance between healthy and yummy can sometimes be a headache for moms, so we asked our Facebook parents for some advice. We asked them what their kids favourite lunchbox snacks and here's what they had to say:
Those mini Marie and Tennis biscuits, peanuts and salty crackers - Somaya Cassiem Meyer
Scooby-Doo! Assorted fruit flavored snacks ( jellies) and Nutrition-Grain Bars as well as the Milo Bars. - Kristabeth Beets
Yoghurt - Lettie Tebza
Nutella sandwich, Woolworths mini viennas and Tuc biscuits - Sure Herbst
Popcorn - Lisa Jeuniaux
Biltong and muffins - Lee-Ann Belinda Patrick
Yoghurt...fruit, scones, crunchies (home-made), pretzels, lays lightly salted, crackers, the list is endless... - Bronwyn Abrahamse
Yoghurt, Melrose cheesies, Fruit Sticks, home made muffins, Provitas with cheese - Dee-Anne Thorburn
Anything home-baked - Janine Dunlop
Cheddars and fruits - Nthateng Mabote
Check out the rest of the responses on our Facebook page.
What are your kids favourite lunchbox snacks?

domain: food


text:
Trans People To Be Excluded From Public Toilets Under Leaked Government Plans
| Last updated
Featured Image Credit: Alamy
Transgender people could be excluded from single-sex spaces such as public toilets in accordance with new government plans.
Leaked sections of a guidance pack from the Equality and Human Rights Commission (EHRC) allegedly say trans people would need to possess a Gender Recognition Certificate (GRC) or risk being denied access to certain places.
Reportedly, as few as 1% of the transgender community currently hold GRCs, meaning these plans could force large amounts of trans people to get legal recognition of their gender and require them to carry paperwork around.
Vice reports that the plans are dated from the end of 2021, and advise shops, prisons and gyms to 'protect women' by banning trans people from single-sex spaces such as toilets and changing rooms unless they can produce a GRC.
For a person to obtain a GRC, they would have to undergo medical assessments and psychiatric interviews to 'prove' their gender.
If these plans came into force, every trans person would have to undergo these assessments and interviews and hope they got the result they wanted.
The UK government does not recognise non-binary as a gender identity and says it has 'no plans' to do so. Last year, it rejected a petition to do so that was signed by around 136,000 people, saying there were 'complex practical consequences'.
Conservative MP Crispin Blunt said, 'It does now appear the rights of trans people are under direct assault in the UK from the public body they would, until now, have expected to be most steadfast in their defence.'
"What the EHRC is reported to be proposing is straight up unlawful. The Equality Act protects all trans people - not just those with a Gender Recognition Certificate. Guidance in that form would not survive legal challenge." https://t.co/y9ema6fKmp— Jo Maugham (@JolyonMaugham) February 10, 2022
Vice also reports that former EHRC staff have told them that Baroness Kishwer Falkner, chair of the EHRC, wanted to 'exclude trans people' from same-sex spaces in workplaces and businesses in order to 'protect women's rights'.
They say that whistleblowers told them Baroness Falkner was 'furious' when department store John Lewis introduced gender-neutral changing rooms and 'pushed for the EHRC to adopt a totally gender-critical position'.
Vice says the report has been written but not yet published, and that a spokesperson for the EHRC did not respond to specific points when questioned, also being unable to confirm or deny whether trans people would need GRCs to access single-sex spaces in the near-future.
A spokesperson for the EHRC said, 'We acknowledge that some EHRC staff have been unhappy, which we regret, and we are working hard to explain decisions and why they are in line with our statutory responsibilities.'
If you have a story you want to tell, send it to UNILAD via [email protected]

domain: sociology


text:
Discarded Medicine Cabinet/Turned Craft Storage
I found this cabinet at Goodwill for $3.It was in good shape.It was cleaned and because it was already white for my cause it just needed touching up.
The cabinet fits perfect between cut outs of the space.
A decorative nob was added that I hand on hand for a little pop of color.
I found some really cute flower adhesive art to use as a floral back ground,going with the theme of my space.Look how organized it came out.Just close the door and its a clutter free space for just a few $.
Enjoyed the project?
Want more details about this and other DIY projects? Check out my blog post!
Published September 18th, 2015 7:51 AM
Join the conversation
3 of 5 comments
Ana illausky on Sep 18, 2015@Hannah V Thanks Hannah!
Devra on Oct 22, 2022
You did such a lovely job and the flower decals on the back were a great idea! I had found an old wood medicine cabinet at a yard sale and knew it had to come back to my little condo. A handyman cut a hole in the kitchen wall between the studs and screwed it in. It's the perfect spice cabinet!
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domain: artistic


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Stock Photo - Pile of old books with glasses on desk 704948
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Kick-Ass is a superhero black comedy film based on the comic book of the same name by Mark Millar and John Romita, Jr. The film was produced in Toronto, Ontario, Canada. It is the first installment of the Kick-Ass film series.
Clearly, Matthew Vaughn is not a man lacking in confidence. Stardust and Layer Cake, his two films to date as director, were entertaining and satisfying; no mean feat. Kick-Ass, though, is an evolutionary leap, and the work of a director ready to gatecrash the A-list.
Shall I have feelings, or should I pretend to be cool? Let's say you're a big fan of the original comic book, and you think the movie does it justice. You know what?
Sign in. Find showtimes, watch trailers, browse photos, track your Watchlist and rate your favorite movies and TV shows on your phone or tablet! IMDb More.
L ike an explosion in a bad taste factory, Matthew Vaughn 's teen-superhero black comedy Kick-Ass is a thoroughly outrageous, jaw-droppingly violent and very funny riff on the quasi-porn world of comic books — except that there is absolutely no "quasi-" about it. Vaughn and screenwriter Jane Goldman have adapted a comic-book series by Mark Millar and John Romita Jr by crushing the essence of Kill Bill, Spider-Man and Ghostbusters to create something fantastically anarchic and gloriously irresponsible: a surrealist fantasy of adolescent wish-fulfilment and fear, sploshed on to the screen in poster-paint colours. In its monumentally mad and addled way, Kick-Ass might even be saying something about the ethics of civilians "having a go" at criminals, about teenagers getting bullied and about our brave new world of homemade internet celebrity.
Dave Lizewski Aaron Johnson is a geek who wonders why no one has ever tried to become a costumed superhero before. The pros are Hit-Girl Chloe Moretz and Big Daddy Nicolas Cagean adorable father-daughter duo who go out for ice cream by day and render criminals into slaughtered remains at night. The performance people will be buzzing about is Moretz.
This setup once could have been read as an allegory for the tribulations endured by the presumptive audience for the comic-book series from which the movies sprang. Another index of the changing pop-cultural times: innone of the major studios were interested in bankrolling the first movie, which was distributed by Lionsgate. By the time the movie was out, she was 13, and the outrage had subsided, perhaps because not many people were interested in paying to see it.
Kick-Ass is the latest in a long line of comic book adaptations to hit the theaters as of late, but it is certainly not your standard fare of people with unusual powers slapping on some fetish-inspired outfits and fighting crime. Kick-Ass is definitely more from the school of works like Watchmen which instead poses the question of what happens when an average person decides to become a superhero? What could possibly make someone risk their lives in such a way to save other people who will look at them as if they are nuts. Dave Lizewski Aaron Johnson is your average high school student that goes through life unnoticed by his classmates save for a pair of friends he goes everywhere with.

domain: entertainment


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Dwarf plants could reduce demands for water, fertilizer, nutrients and pesticides
Aside from arable land, most farm crops require significant amounts of water, fertilizer, nutrients and pesticides to grow. While specialized breeding is often used to help produce plants that require less of these inputs, Purdue University researcher Burkhard Schulz has found a way to create tiny versions of plants that suffer no reduction in yield through the addition of a cheap and widely available chemical.
In previous research, Schulz, an assistant professor of plant biochemical and molecular genetics, had found that using the chemical brassinazole to inhibit the steroid function in corn plants resulted in tiny versions that had only female sex characteristics. But at a cost of as much as US$25,000 a gram, the chemical was prohibitively expensive, prompting him to search for a cheaper alternative.
He found a much cheaper option in the form of propiconazole, a fungicide used to treat fungal dollar spot disease on golf courses. Not only does it cost around just 10 cents a gram, but it is also more potent than the much more expensive brassinazole. It is also recognized as a safe chemical for humans with Schulz pointing out that, "they treat golf courses with it. People are around it every day."
Schulz’s previous work adding brassinazole and altering genes to disrupt steroid production produced short, feminized versions of corn plants that developed more kernels where pollen would normally grow. His new findings show that the same results can be achieved using the cheaper and widely available fungicide propiconazole.
"We can change the architecture of a plant the same way that has been done through breeding. We can treat plants with this substance throughout the plant's life and it will never be able to produce steroids," said Schulz. "Any research where you needed to treat large plants for long periods of time would have been impossible. Those tests before would have cost us millions of dollars. Now, they cost us $25. This will open up research in crops that was not possible before."
Aside from the benefits to researchers, Schulz’s approach could also be used to produce shorter plants that not only produce the same amount of grain using less water, fertilizer and nutrients, but are also sturdier against the elements thanks to their reduced height. The technique could also be used to slow grass growth on golf courses, reducing the amount of mowing required and cutting costs.
The findings could also prove significant for seed producers who must usually perform the labor-intensive task of mechanically removing the male portion of the plants so they don’t pollinate themselves.
Schulz and his team are working to determine which genes propiconazole affects and they plans to test if the chemical will also retard steroid production in grain crops other than maize. The team's recent findings were published in the journal PLoS One.
Schulz explains his technique and its benefits in the following video.
Source: Purdue University

domain: agronomy


text:
Good with: Cats
Energy level: Relaxed
Milo was found on the north side on January 24, 2018 and was not claimed. He loves being pet and getting attention from people. When you stroke the top of his nose he affectionately looks up at you, closes his eyes and slightly opens his mouth, he’s in pure bliss. When not getting attention, he is an easygoing, independent guy who loves to play with toys filled with catnip and to spend his day napping in the window hammock.

domain: pet


The Department of Nuclear Engineering offers a graduate certificate in nuclear security science and analysis. The program is designed primarily for students seeking specialization in nuclear security science with emphasis on current or aspiring members of the nuclear security community, including those areas with an emphasis on arms control, treaty verification, nonproliferation, international nuclear security issues in both civilian and military contexts, nuclear threat detection, and principles of nuclear intelligence assessment. Additionally, this program prepares graduate students to engage in the research and development of new tools and processes related to nuclear security science and analysis.
NE 531 Global Nuclear Security Culture
Principles and best practices in nuclear security, nuclear safety, and nuclear materials safeguards (“3S”) culture with an emphasis on developing and expanding nuclear power-producing states. Introduction to relevant international conventions and agreements such as the Nonproliferation Treaty, the role of the International Atomic Energy Agency, and the key milestones for nations seeking to develop a peaceful nuclear power program.
NE 533 Physical Security for High-Consequence Facilities
Design criteria and performance basis that make up a physical security program for high-consequence and critical environments. Introduction to security design and engineering technology forming the basis behind detection, delay, and response elements of security systems. Elements of risk, system evaluation, site and security surveys, and the legal basis for protection. Evaluative methodologies common to academia and industry will be applied.
NE 534 Physical Security Vulnerability Assessment
Evaluation of threat basis, facility characterization, and asset determination. Students will engage in field surveys, perform interviews, and gather open-source information which provides the background information necessary to evaluate system effectiveness from a quantitative perspective. Evaluative and analytical approaches necessary to perform physical security vulnerability assessments and development of models designed to predict the effectiveness of systems.
NE 535 Nuclear Chemistry and Radiochemistry
Introduction to nuclear and radiochemistry. Principles of radioactive decay, radiochemical separations, and radiochemical measurements. Nuclear cross-sections and isotope production methods. Applications of nuclear and radiochemical techniques in medicine, environment, and industrial applications.
NE 536 Export Control and Nonproliferation
Principles and regulatory frameworks for controlling sensitive nuclear technology. US and European export control regulations and governance, international export control, and nonproliferation considerations for nuclear technology trade in the global context. Best practices resources such as the International Atomic Energy Agency, the Nuclear Supplier Group, and other organizations. Case studies in export control violations relevant to nuclear proliferation.
NE 537 Human Reliability in Nuclear Systems
Methodology for assessing and managing human reliability factors in nuclear systems. Issues in human reliability and human sources of error in nuclear systems performance. Indicators and issues in identifying and minimizing the impact of human actions (accidental or deliberate) adverse to successful operation in nuclear systems and nuclear materials security.
NE 635 Nuclear Forensics
Introduction to nuclear forensics. Principles of isotopic signatures and their origins, ultra-trace radiochemical separations, and isotope measurements via nuclear counting and mass spectrometry. Forensic assessment methods for nuclear materials and post-detonation debris analysis. Applications of nuclear forensics in interdicted materials and crisis response scenarios.


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AC Milan are being threatened with charges over fraud by Italian prosecutors after a report over Silvio Berlusconi's sale of the club to Far East investors surfaced.
Berlusconi is being investigated over money laundering, according to Italian news publication La Stampa (h/t Football Italia) and his financial dealings could have repercussions on both I Rossoneri and their current owner Yonghong Li as a result.
Both La Stampa and La Gazzetta dello Sport have now claimed that a 12-page document has been put forward to the tax office - La Guardia di Finanza - ahead of a potential charge being brought against the former Italy president and the sleeping Serie A giants.
Italy's chief prosecutor has denied that any case has been officially opened up against Berlusconi, while the 81-year-old has ridiculed the allegations as mere conjecture and doesn't believe he has a case to answer.
Three suspicious payments - each comprising of €100m each - were been made ahead of Li's takeover of Milan, however, and it is these transactions that the authorities want to get to the bottom of before deciding whether to file a charge or not.
The cash arrived in Italy via a succession of different nations such as Hong Kong, China, Virgin Islands and Cayman Islands - the latter two of particular concern due to their supposed 'tax haven' statuses.
(You may also be interested in 'For Now, I Only Want to Stay': Suso Responds to Rumours Over Alleged £43m Liverpool Return)
Other vital information relating to Li's takeover is also missing, and that lack of data is only adding fuel to the fire about financial laundering having taken place between Berlusconi and Milan's new bank rollers.
Deputy prosecutor Fabio De Pasquale has a few more days to mull over the small print of the deal and, if he feels there is sufficient evidence to press charges, the Italian tax office shall do so.
De Pasquale was also the man behind Berlusconi being embroiled in a separate tax fraud case that prevented him from running for Italy's Prime Minister post again - a verdict which prevents him from running for public office until 2019.
Berlusconi had sold Milan to Li's consortium in April 2017 for around £650m after months of negotiation.

domain: news


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Food sensitivities can cause a wide range of symptoms and disorders. The foods that cause these delayed reactions are often hard to diagnose because of the time between consumption and the physical reaction. The IgG food allergy test offers a useful tool for detecting the foods causing this response. The results are patient specific and provide an easy, precise and effective starting point for dietary manipulation.
IgG (immunoglobulin G) testing is a useful guide for practitioners to structure an elimination diet for many chronic health conditions. The foods that cause these delayed reactions are often hard to diagnose because of the time between consumption and the physical reaction. Generally, an IgG reaction occurs hours to days after exposure to these food antigens.
The IgG food allergy test offers a useful tool for detecting the foods causing this response. The results are patient specific and provide an easy, precise and effective starting point for dietary manipulation.
When doing an IgG test, it is recommended to eat a large variety of foods in the two weeks prior to testing. Include as many of the foods that are being tested in the specific allergy panel you have chosen. Be aware that if foods are not included in the diet during this time, false negative results may be obtained as recent exposure to these foods may be required for antibodies to be present in the blood.
- Irritable Bowel
NOTICE TO PATIENTS
WellLab practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. WellLab can offer assistance in locating a suitable practitioner.
Dairy: Casein, Cheese-Cheddar, Milk, Milk-Goat, Whey
Fish/Crustacea/Mollusk/SeaFood: Anchovy, Clam, Cod, Crab, Halibut, Lobster, Octopus, Oyster, Red Snapper, Salmon, Scallop, Shrimp, Sole, Squid, Tilapia, Tuna
Fruits: Apple, Banana, Cantaloupe, Cherry, Grapefruit, Green Grape, Guava, Jackfruit, Kiwi, Lemon, Mango, Olive, Orange, Papaya, Peach, Persimmon, Pineapple, Strawberry, Watermelon
Grains/Legumes/Nuts: Almond, Bean-Kidney, Bean-Lima, Bean-Soy, Buckwheat, Cashew-Nut, Chestnut, Chickpea, Coconut, Corn, Gliadin- Wheat, Gluten-Wheat, Lentil, Millet, Oat, Pea-Green, Peanut, Pine Nut, Pistachio, Rice-White, Walnut- English.
Meat/ Fowl: Beef, Chicken, Duck, Goose, Lamb, Pork
Meat/ Fowl: Egg White-Chicken, Egg Whole-Chicken, Egg Yolk-Chicken
Misc/ Herbs/Spices: Basil, Black Tea, Cinnamon, Coffee Bean, Coriander, Curry Powder, Ginger, Honey-Bee, Mushroom, Mustard, Pepper-Black, Sesame Seed Sunflower Seed, Vanilla Bean, Cocoa Bean, Yeast- Baker’s
Vegetables: Avocado, Beet, Broccoli, Cabbage, Carrot, Cauliflower, Celery, Cucumber, Eggplant, Garlic, Green Bean, Lettuce, Onion, Pepper-Green Bell, Potato-Sweet, Potato-White, Spinach, Tomato


"It may be that aviation is the place we use fossil fuels," Lord Adair Turner tells London conference
Attempts to decarbonise the aviation sector could ultimately prove futile, the head of the government's climate change advisory body has warned. Lord Adair Turner, chairman of the Committee on Climate...
Theresa May calls on EU to agree to transition period under 'existing structure of EU rules and regulations'
Mayor Andy Burnham kicks off congestion consultation with launch of the UK's first electric bus to be recharged using a pantograph
Engineering giant predicts 'sustained growth' from its Clean Air division, as it announces plan to expand investment in battery technologies
In her long-awaited Florence speech May is expected to outline proposals for a two-year transition framework for Brexit, effectively keeping Britain subject to EU environmental law until at least 2021


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Sun Safety Tips for Infants and Toddlers
Posted on 03 June 2016
Here are some of the best ways to protect your children from the sun, from The Skin Cancer Foundation.
0-6 months: Infants under 6 months of age should be kept out of the sun. Their skin is too sensitive for sunscreen.
An infant's skin possesses little melanin, and cannot regulate their body temperature by sweating the same way older children can. Therefore, babies are especially susceptible to the sun's damaging effects.
- I invest in UV window film, which can screen almost 100 percent of ultraviolet radiation without reducing visibility.
- Take walks early in the morning before 10 AM or after 4 PM and use a stroller with a sun-protective cover.
- Dress baby in lightweight UPF clothing that covers the arms and legs.
- Choose a wide-brimmed hat or bonnet that protects the baby's face, neck, and ears. A baby who wears a hat during the first few months will get used to having it on.
6-12 months: It's now safe to use sunscreen on babies.
- Apply broad-spectrum, SPF 50+ sunscreen to areas left uncovered such as baby's hands. Many companies have tear-free formulas that won't sting baby's eyes.
- Sunscreen must be applied 30 minutes before going outside and reapplied every two hours or after swimming or excessive sweating.
- Sun protective clothing remains the most effective and convenient form of protection.
Protecting toddlers from the sun requires a little more thought and effort. It is important to educate your child and caregivers.
- Look for broad-spectrum sunscreens with an SPF 30 or higher.
- Make sure your child seeks the shade between 10 AM and 4 PM. Check the outdoor area where your child plays to make sure there is adequate shade.
- Make sure toddlers are covered. Clothing with an Ultraviolet Protection Factor (UPF) listing on the label offers extra security. While Skin Cancer Foundation recommends clothing with a UPF of 30 or higher, Little Leaves sun protective clothing comes with a UPF 50+ rating, blocking 98% of UV rays.
- Don't forget hats and sunglasses. Choose a wide-brimmed hat that protects face, neck, and ears.
"With a little effort and planning, it's easy for young children to enjoy the outdoors safely," said Dr. Carley Gomez-Meade, pediatrician and Little Leaves Clothing co-founder. "Parents need to make it a priority, and to also lead by example."


It’s over 80 degrees outside, but Brandon Dixon, 17, is wearing a thick blue blazer and a polo shirt with the word “Girard” embroidered just above his heart.
The high school senior has pulled off a pretty big feat.
“I applied to 11 colleges, and I got into all of them. It was Stanford, Harvard, Yale, Columbia, the University of Pennsylvania, Swarthmore, Wesleyan, Kenyon, Middlebury, Duke and…”
He pauses for a few seconds. “I’m forgetting one … Dartmouth. I don’t think I said that one.”
The accolades don’t stop there. “I got the [Bill and Melinda] Gates Millennium scholarship a couple of weeks ago, and that pays for your education all the way through to your doctorate level,” said Brandon. “There’s no word to describe how great that is, because you’re set for the rest of your education.”
Brandon doesn’t attend an exclusive private school, nor one of Philadelphia’s top-tier public school magnets. For the last seven years, he’s studied and lived at Girard College, a selective admission boarding school in North Philadelphia.
The K-12 boarding school began in 1848 with an endowment from wealthy Philadelphian Stephen Girard and a mandatee to educate poor orphans and children of single parents. At first, the school served only white boys, but after a desegregation battle in the 1960s, its student body now has slightly more girls than boys and is primarily black and Latino.
Today, its 259 students can get an education and live at the school for free, thanks to a “uniquely private/public structure,” said communications director Polly Mitchell.
Boarding school bonds
Brandon resides at the school five days a week, going home to his mom in North Philadelphia on the weekends. While every student has to test into the school and meet the low-income and single or no parent requirements, he said he is somewhat of an outlier in his upbringing.
“A lot of my friends have been in West Philadelphia, South Philadelphia, the harder areas of the city,” said Brandon. “Some of them have seen some of their family members shot or in jail. And I’ve never had that experience.”
Students live in dormitories on the school’s lush 43-acre campus, which stretches across Girard Avenue between Corinthian Avenue and 25th Street. A stone wall encircles the school’s Greek Revival- style buildings, a grand contrast to the typical Philadelphia rowhomes just beyond the gates.
Living at school means students form deep bonds with their teachers and resident advisers, Brandon said. One teacher, Upper School science teacher Scott Sowers, taught him a lesson that he spun into college application gold.
“The essay that I wrote for my Common App essay was about how my physics teacher gave me a Rubik’s cube in ninth grade, and he intentionally turned it so it was unsolvable,” said Brandon. Sowers had taken off one of the “cubits,” the small squares that make up the iconic Rubik’s cube grid, and put it back in a different position.
Brandon spent three months fiddling with the tampered cube. As a member of the schools’ Rubik’s cube club, he could normally solve the puzzles in under a minute.
“He knew that I was the type of person who liked to take on new challenges, and I sort of got ahead of myself sometimes,” said Brandon. “So he was trying to teach me a lesson about humility.”
Finally, on Sowers’ wedding day — the ceremony was held on Girard’s campus — he showed Brandon what he’d done. “I was like, ‘What?’ He was like, ‘Yeah, I got you.’ And then he walked away.”
He’s careful to share that many of his classmates are also bound for well-ranked four-year universities. Pointing at seniors seated around the same lunch table, he ticks off his cohorts’ destinations: “He’s going to Pitt, you’re going to Carnegie Mellon … Charles is going to Wesleyan.”
But the honor students gathered around the table almost didn’t graduate from Girard College.
The fight for Girard College
In the landscape of K-12 education in Philadelphia, Girard College occupies a unique position. While technically a private boarding school, the college is run by a public trust bequeathed by Stephen Girard to the City of Philadelphia in 1830.
His will is administered by the Board of Directors of City Trusts, a group overseeing all the estates left to the City of Philadelphia, of which Girard’s is the largest. The group consists of “12 citizens of Philadelphia, the mayor and the president of City Council, who serve ex-officio,” according to the group’s website. Those citizens include former politicians, lawyers and lobbyists.
When the current seniors were sophomores, the board pleaded that the Great Recession had hit the estate’s bottom line hard, and tried to shut down the high school and the school’s dormitories.
Students, teacher and alumni joined together to protest the board’s decision. Brandon and his peers joined in the response, and he testified in Orphans’ Court about why the school should not cut back.
“I told them … you have a whole campus of kids that have been sheltered their entire life. If you tell them right now that you can’t graduate from school where you’ve been living your entire life, [you’re] pretty much throwing them out into the jungle of Philadelphia.”
In the end, the courts sided with the students. But the board has appealed that ruling.
Even though Harvard is pulling him away from Philadelphia, Brandon said he’s still committed to the cause. “As soon as I find out any information about the appeal or if i can testify in court, then I’ll definitely come back and testify.”
It’s at Girard, after all, where he stumbled upon his passion for administration and politics.
“They call me ‘the head’,” said Brandon. “Part of that is because I have a big head, but also because I’m the head of all the activities on campus.”
His practice leading fellow students, advocating for change to the school’s administration and a catalyzing U.S. history class have left him with one overarching ambition. “My ultimate goal is to be president of the United States,” said Brandon.
If the White House doesn’t work out, his next choice is to start his own school, modeled on the values of Girard College.


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Aaah the UK. They just don’t seem to have had luck on their side at the Eurovision Song Contest of late. Combined with an anti-UK sentiment across the continent, the wheeling out of long-forgotten vocalists (Engelbert and Bonnie, anyone?) and some genuinely shit song choices, they haven’t placed in the top ten since 2009.
So they’ll be hoping to reverse the trend in 2015, with UK duo Electro Velvet tasked with bringing Eurovision glory home to Britain.
‘Still In Love With You’ is interesting and is virtually guaranteed to stick out no matter what. It’s a little bit ‘Doop’, a little bit ’20s, perhaps even a little bit Mika. So the combination could very well sway some extra votes from the continent.
Naturally, the UK doesn’t have to worry too much because, as part of the “big six”, they’re guaranteed a place in the Grand Final. Six points.


As we reported earlierChris Brown and Odd Future's Frank Ocean have been tangled in an ongoing twitter war. Now it looks like things are getting serious.
Okay. Story is, Frank Ocean came down to Chris' dance rehearsal in L.A. looking for him. However, he started running when he actually saw him. Chris' cousins, Mijo and Trell, spotted him as he was fleeing and then this happened. All this resulted from Frank's and Chris' Twitter beef.
After releasing his new project WINDY, The Boy Illinois kills Sway in the morning freestyle in NYC. While meeting with major publications including XXL Mag and Thisis50.com, The Boy Illinois is stirring up a major Buzz surrounding his new project. Check out the new interview and freestyle on Sway in The…See More


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Rub raw, peeled and de-veined shrimp, 1/2 inch thick slices of yellow squash and zucchini, with olive oil. Combine in a nonstick skillet at medium heat. Sprinkle liberally with Bear Claw Shrimp Spice and saute until shrimp are done. Serve warm and with fettuccini.
Wow! Grilled Cheese Sandwiches, Eggs, Veggies and Chicken.
Mild Cajun flavor.


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View all facilities
City Water & Light Park
- Picnic Tables
- Soccer Field
About City, Water, and Light Park:
Just a few turns down from Craighead County Public Library, CWL Park is a fun, little spot that provides a playground and soccer field for practice and fun! With convenient operating hours, CWL is perfect for families in the area looking to spend some time outdoors, while also being nearby the many local restaurants provided in Downtown Jonesboro!

domain: library


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Several reports have suggested that BlackRock could become the first issuer of a spot Bitcoin ETF in the US if approved, but that may not be the case, according to some executives and analysts.
Other industry observers, including Bloomberg Intelligence ETF analyst James Seyffart, have argued that ARK and 21Shares should be ahead of everyone to set up a spot Bitcoin ETF.
“21Shares, ARK and Cboe [Chicago Board Options Exchange] While we don’t yet have a date for other 19b-4 filings like BlackRock’s, they are in the first place as the next SEC decision date is August 13, 2023.”says Seyffart.
Many industry players have pointed out the timing of BlackRock’s deposit of the Bitcoin ETF, e some claim the firm may have inside information about the SEC’s policies regarding BTC ETFs.
The new shirt released by @EricBalchunas…
I must say that it is hard to believe that this is a coincidence:
BlackRock deposits a BTC spot ETF
The other 4 streamers are fast following the same
Launch of EDX crypto exchange (powered by Fidelity, Schwab etc.)
SEC approved 2X leveraged btc futures ETF
drop new t-shirt @EricBalchunas…
I’ll say it seems hard to believe that all this is a coincidence:
BlackRock files for spot btc ETFs
The other 4 issuers are fast following the case
EDX crypto exchange launches (powered by Fidelity, Schwab, etc.)
2X leveraged btc futures ETF allowed by SEC pic.twitter.com/5CfG7ThcLg
— Nate Geraci (@NateGeraci) 26 June 2023
Despite growing optimism about the potential for a spot Bitcoin ETF to come to the US market, many experts believe that such products will not be released in the near future.
“The SEC is unlikely to approve a spot Bitcoin ETF in 2023, as the issue has not progressed much since the Winklevoss twins filed for ETFs in 2017.”Wilshire Phoenix partner Wade Guenther told Cointelegraph.
Related: Bitcoin ETF fever: ProShares ‘BITO’ fund sees biggest inflow in a year
“Not much has improved since many of these sponsors first deposited their original spot Bitcoin ETFs”Günther added:
“As there is still some time for review, we do not believe that a spot Bitcoin ETF will go public anytime soon. Therefore, it may not be until next year, possibly next year, that we will see a spot Bitcoin ETF.”
Previously, co-founder of ETF Institute Nate Geraci He predicted there would be no spot Bitcoin ETF in 2023.
Translation of Walter Rizzo

domain: finance


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Paediatric nurse Deirdre Morley, who was found not guilty of the murders of her three children by reason of insanity, has been committed to the Central Mental Hospital (CMH).
A Central Criminal Court judge made the order on Tuesday morning, nearly three weeks after a jury returned the special verdicts following the trial of the 44-year-old clinical nurse.
Mr Justice Paul Coffey said Ms Morley continues to suffer from a mental disorder under the meaning of the legislation and is in need of inpatient care at a designated centre.
Ms Morley, of Parson's Court, Newcastle, Co Dublin, had pleaded not guilty by reason of insanity to the murder of her sons, Conor McGinley (9) and Darragh McGinley (7), and her daughter, Carla McGinley (3).
The children’s bodies were discovered at the family home just before 8pm on January 24th last year.
On May 20th, Ms Morley was found not guilty by reason of insanity after a jury accepted the evidence given by two psychiatrists that the accused, who specialised in renal care at Our Lady's Hospital in Crumlin, was suffering from a mental disorder at the time of the three killings and fulfilled the criteria for the special verdict.
The two consultant forensic psychiatrists called as expert witnesses were both in agreement that the accused was unable to appreciate what she had done was morally wrong and was unable to refrain from her actions.
Following the verdicts, trial judge Mr Justice Coffey made an order committing Ms Morley to the CMH in Dundrum until May 31st so that an approved medical officer could prepare a psychiatric assessment.
The case was adjourned on that date to allow time for lawyers to consider the psychiatric report.
The matter was back before the court on Tuesday when defence counsel Michael Bowman SC told Mr Justice Coffey that the court had the report and both sides had read it.
Ms Morley, who did not speak during the hearing, appeared via video-link from the CMH.
Consultant forensic psychiatrist Dr Ronan Mullaney from the CMH, who conducted the examination on Ms Morley, also appeared on the video-link for the brief hearing at the Central Criminal Court.
Mr Justice Coffey said that Ms Morley had been found not guilty by reason of insanity on the three counts and he had previously directed that she be assessed by an approved medical officer.
“I’ve received and considered the report of approved medical officer Dr Ronan Mullaney including his findings,” he said.
The judge said he was satisfied that Ms Morley continues to suffer from a mental disorder under the meaning of the legislation and is in need of impatient care at a designated centre.
He then made an order committing her to the CMH for further inpatient care under the Criminal Law (Insanity) Act.
Under the Act, Ms Morley’s condition will be reviewed every six months by the Mental Health Review Board.
Prosecution counsel Anne-Marie Lawlor SC said that Tuesday’s order now disposed of the case.
Ms Morley’s three-day trial at the Central Criminal Court was described by the State as “a desperately sad case”.
The case, Ms Morley’s defence counsel had told the jury, was a “tragedy of enormous proportions”, with the “tragic irony” of the accused being someone who had committed her entire professional life to the care of children as a paediatric nurse.
Assistant State Pathologist Dr Margot Bolster found the children had died by asphyxia from compressions of the chest area and airways.
Dr Brenda Wright, called by the defence, gave a detailed description of the accused's mental state deteriorating in the weeks before the killing and said she was suffering with bipolar affective disorder at the time. The witness said the defendant believed it was morally right to smother her three children as she thought she had "irreparably damaged" them and "had to put an end to their suffering".
Dr Mary Davoren, for the prosecution, testified that the accused was suffering at a minimum from recurrent depressive disorder and experienced a severe depressive episode on the day.
In her opening address, prosecution counsel Anne-Marie Lawlor SC said the jury’s primary concern would be the accused’s mental state on January 24th and there was no issue in the case as to what happened to the children and how they died.

domain: law


In FIFA World Cup 2022 where teams are clashing with each other in one side match. On the other hand, on November 28, a major accident took place here. A bus carrying Swiss players collided with a police car. The clash took place ahead of Brazil’s clash with Switzerland on Monday. All the players were going to Stadium-974 in Qatar by bus. Brazil won the match 1-0.
According to information, when the bus collided, it was on a low speed, due to which the players were not harmed. In fact, there was a long jam on the road leading to the stadium. Due to this jam, the vehicles were moving very slowly. Meanwhile, the bus of the players collided with the police car moving ahead. Although it was a relief that no one was harmed in this accident and the players reached the ground while being safe and the game was organized.
match like this
The Brazilian football team, without its star striker Neymar, beat Switzerland 1.0 in the World Cup match. Entered the last 16 by defeating 0. After a boring first half, Casemiro opened the scoring for Brazil in the 83rd minute. Five-time champions Brazil have yet to play their last match in Group G but the team has already booked a place in the pre-quarterfinals. After this win, Brazil have six points from two matches and Switzerland have three points. Serbia and Cameroon have one point each who have scored 3. Played a draw from 3. Switzerland will have to beat Serbia in their next match to advance to the next stage. The match between Brazil and Cameroon will depend on whether the Swiss team will be able to advance to the next stage even if the match ends in a draw.
With the win, Brazil’s unbeaten run in the group stage extended to 17 matches, including 14 wins and three draws. They have lost only one of their last 29 group matches against Norway in 1998. Switzerland have lost only two of their last 13 group matches in the World Cup. Both the teams did not create many chances in the first half. Without Neymar, the Brazilian team found it difficult to attack the Swiss goal. Brazilian coach Tite replaced Neymar with midfielder Fred. Richarlison, who scored both goals for Brazil in the first match, did not appear in form today and was replaced by another player in the second half. Vinicius Junior scored for Brazil in the 64th minute but was ruled offside after a video referral.


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FBI Admits Flaws in Hair Analysis Over Decades
For three decades, an FBI forensic lab used flawed scientific analysis of hair samples to help prosecutors. Roughly 2,500 cases are now being reviewed.
—Tom Simonite, San Francisco bureau chief
Elon Musk Had a Deal to Sell Tesla to Google in 2013
How the electric car company faced bankruptcy in 2013 and started negotiating a sale to Google.
Seth Stevenson evaluates how likely four compact motorized vehicle-like thingamajigs are to kill you or make you look like a dork.
—Linda Lowenthal, copy chief
How One Man Crashed the Stock Market
Navinder Singh Sarao found a loophole that he used to manipulate the market for years.
—J. Juniper Friedman, associate Web producer
Drone Strikes Reveal Uncomfortable Truth: U.S. Is Often Unsure About Who Will Die
We don’t know who we are killing with drones.
—Antonio Regalado, senior editor, biomedicine
Chinese Scientists Genetically Modify Human Embryos
In a world first, Chinese modify human embryos with gene editing.
What’s That On Beyoncé’s Wrist? Let Me Guess … an Apple Watch
What Apple’s marketing strategy says about its latest gadget.
—Will Knight, news and analysis editor
Why the Flash Crash Really Matters
An interesting piece suggesting that the emergent nature of financial market phenomena may make catastrophic crashes hard to foresee.
Bitcoin’s Problem with Women
Mother Jones takes on the “crypto-patriarchy” of the great Bitcoin experiment and why homogeneity will be its downfall.
—Kyanna Sutton, senior Web producer
Stackable Brain Specimen Coasters Reveal a 3D View of the Human Brain
This is your brain… on coasters.
This artist is dominating AI-generated art. And he’s not happy about it.
Greg Rutkowski is a more popular prompt than Picasso.
This nanoparticle could be the key to a universal covid vaccine
Ending the covid pandemic might well require a vaccine that protects against any new strains. Researchers may have found a strategy that will work.
How do strong muscles keep your brain healthy?
There’s a robust molecular language being spoken between your muscles and your brain.
The 1,000 Chinese SpaceX engineers who never existed
LinkedIn users are being scammed of millions of dollars by fake connections posing as graduates of prestigious universities and employees at top tech companies.
Get the latest updates from
MIT Technology Review
Discover special offers, top stories, upcoming events, and more.


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About us: This database is an ongoing project of the Library & Information staff at the Alcohol and Drug Abuse Institute, University of Washington.
Jul 3, 2013. They found that recent suicide attempts in severely depressed individuals. 1 ( NK1) substance P systems are known to modulate 5HT neurons.
standing the role of substance P in the brain has been greatly complicated by marked. control of emesis and depression, these compounds do not appear to.
Depression is a state of low mood and aversion to activity that can affect a person’s thoughts, behavior, feelings, and sense of well-being. A depressed.
Substance P is thought to have a role in the regulation of pain, asthma, psoriasis. and CSF studies of substance P in depressed subjects are not in agreement.
Substance P (for “powder”), identified as a gut tachykinin in 1931 and involved in the control of multiple other autonomic functions, notably pain transmission,
Public health practitioners have attempted to look at substance use from a broader perspective than the individual, emphasizing the role of society.
Quotes About Depression And Death A collection of quotes attributed to British author J. K. Rowling. J. K. Rowling quote. I have never been remotely ashamed of having been depressed. Never. It is the unknown we fear when we look upon death and darkness, nothing more. About: Love quotes, God quotes, Depression quotes, Rejection quotes, Spirituality quotes. Suicide quotes, Death
Learn about depression symptoms in men, women, teenagers, and children. Plus, read about treatment, medications and side effects, causes, and diagnosis.
Abstract: Substance P (SP) levels are closely related with the pathogenesis of. the lateral habenula (LHb) plays a key role in the pathogenesis of depression.
We have investigated the role of the neuropeptide SP and its preferred receptor, Keywords: Substance P; Neurokinin-1; NK-1R antagonists; HIV; Depression.
Research on Substance P (SP) has, until recently, focused on its role in pain and inflammation. However, a report that NK(1) receptor antagonists have utility in.
Substance P is a neuropeptide that acts as a neurotransmitter or. CLINICAL STUDIES OF NK1 RECEPTOR ANTAGONISTS IN DEPRESSION. Ebner, K. & Singewald, N. (2006) The role of substance P in stress and anxiety responses.
Although risk factors for childhood and adolescent depression can be categorized as biologic, psychologic, or environmental , these factors are often.
CIHS provides clinical practice tools and resources for integrating mental health, substance use, and primary care. Consult with our subject matter experts.
Substance P (SP) is an undecapeptide member of the tachykinin neuropeptide family. It is a. The sensory function of substance P is thought to be related to the. To be populated re IL6, immunology of depression/anxiety, psycho-immune.
Increasing evidence implicates the substance P (SP) neurokinin-1 receptor system in. depression and anxiety in patients with major depressive disor- der and a. (e.g., central, basolateral, and medial) seem to play a role in emotional.
December 2014 Issue. CPE Monthly: Substance Abuse and Nutrition By Alyssa Salz, MS, RD, LD Today’s Dietitian Vol. 16 No. 12 P. 44. Suggested CDR Learning.
May 17, 2017. Keywords: Peptides, Mood disorders, Substance P, Neuropeptide Y. Accepted. The prominent role hypothesis in depression research is the.
LifeWorks unifies employee engagement with unrivalled EAP & Wellness programs, Perks, Social Communication & Recognition
Depression affects millions of people around the world. According to the Centers for Disease Control and Prevention (CDC), about 18.8 million adult.
Find patient medical information for 5-HTP on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products.
Can Add Cause Depression Anxiety Mar 21, 2014. Separating RLS from depression can be like trying to unscramble an egg. non- SSRIs like Wellbutrin or the tricyclics don't seem to cause the. It's important to remember that anxiety can range from occasional, mild and. The same study found that just 1 in 10 children with autism and ADHD were. Because
An allergic reaction occurs when the immune system attacks a usually harmless substance called an allergen that gains access to the body. The immune system.
Evidence implies a role for corticotropin-releasing hormone (CRH) and tachykinins, e.g. P (SP) and neurokinin A (NKA) in the pathophysiology of depression.
A review of the research literature indicated that exercise may serve as a useful adjunct for acute treatment of substance use disorders and also prevent.
Advances in research of substance P. the mood disorders (depression, etc), schizophrenia and other psychotic disorders. This radioligand tracer shows great potential in the further study of the role and activity of substance P in the brain.
Fathers’ involvement in and influence on the health and development of their children have increased in a myriad of ways in the past 10 years and have.
An investigational compound that blocks the neurokinin "substance P" has demonstrated robust. They rapidly progressed to a phase II clinical test in patients with depression (Kramer et al.,1998). Its function has remained elusive.
Studies to further characterize the role of substance P as a modulator of pain. [ 30-32] Much of what is understood about the neurobiology of depression results.
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- Natural Ways To Overcome Clinical Depression: How to beat depression - without drugs. Up to 20% of the UK population will have clinical depression at some point, he says - twice as many as 30 years ago. Learn About Copay Savings on an Add-On Rx Treatment For Adults w/Depression. Consider Antidep...
- Clinical Depression And Alcohol: Read about depression, including how to tell if you're depressed, the treatments for different severities of depression, and how making lifestyle changes can help. May 31, 2017. Clinical depression, also referred to as major depressive disorder, is a...
- Cns Respiratory Depression Symptoms: Morphine should be administered cautiously to avoid additive effects when other central nervous system. respiratory and CNS depression. symptoms also. Cyberfriends: The help you're looking for is probably here. This website collects no information. I...
- Companies That Made Money During The 1929 Depression: It is far too simplistic to view the stock market crash as the single cause of the Great Depression. A healthy economy can recover from such a contraction. The depression and industry finances - Great Depression - film, movie on Film. companies that ...
- Anxiety And Depression Clinics: The Linden Method - Linden Tree Education's program by Charles Linden. Mobile enabled self-help with unlimited guidance by qualified psychologists and. CBD oil for Anxiety and Depression. Over the years, cannabis oil has been used as an effective tre...
- Herpes Virus And Depression: [embedyt]//www.youtube.com/embed/BGRlKTT_YhI[/embedyt] Nov 5, 2011. The association of depression, risky sexual behaviours and herpes simplex virus type 2 in adults in NHANES, 2005-2008. (PMID:22057015). ABSTRACT. The persistence of herpes simplex vi...

domain: psychology


Tags: 694+ Optidrive inclined screener
Terex Finlay hosted its largest-ever Customer Open Event in June in Scotland, where the company demonstrated 13 crushing and screening equipment models. More than 300 end users and dealers from across the world attended the 3-day event at Jim Jamieson’s Quarry ...
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Skull and Cross Buns Rubber Stamps Baby Barn Owl Hand Carved Rubber Stamp
Baby barn owl hand carved rubber stamp designed by Skull and Cross Buns. Owls are really popular in the crafting world at the moment, how about adding this cute baby Barn Owl to your projects? Don't forgot to use him at Halloween time too! Teams up perfectly with all my other woodland designs too. These stamps are not suitable for young children and do not come supplied with ink pads. High quality carving rubber mounted on wooden blocks made within from the UK. All stamps in the Skull and Cross Buns range are painstakingly designed and delicately hand carved by me in my little South Devon studio by the sea. The stamp may var
Little Red Press Keep Calm And Make A List Pocket Notebook
Sturdy, card cover version of the iconic Moleskine notebook with letterpress printed 'Keep Calm' slogan.
Child's Sewing And Knitting Suitcase
A charming old fashioned French sewing and knitting box, containing everything needed to get going with some fabric crafts. The suitcase and packaging is vintage in design and really beautiful to look at, but all the equipment and accessories are thoroughly practical too. The kit contains: five balls of wool, four embroidery threads and three sewing threads - all in bright, pretty colours, a pair of wooden knitting needles, three darning needles, crochet needle, tape measure, scissors, thimble, four little buttons and a French wooden knitting dolly. All you would need to add is a bit of fabric and maybe a bit of advice - please note that there are no projects or instructions included, so an adult with a bit of experience would be a great asset! The suitcase itself - which will make a lovely sewing box - is made of sturdy cardboard with metal clasp and carrying handle. It measures 26cm x 18cm x 9cm. Please note that the suitcase set has been designed in France so the pretty lettering on the front and packaging is in French - but I think this just adds to the charm and style of this suitcase of 'couture'! Not suitable for children under six years.
Decorate Your Own Easter Bag - Duck Or Rabbit
Craft activities are so much fun, and a great opportunity for children to be really creative. This fabulous little Easter Egg bag decorating kit, designed by us, contains one cotton fabric bag, felt fabrics, a set of fabric crayons that can be fixed in place with a light iron, some mini pom poms and goggly eyes! Children can cut out a rabbit or duck shape from the sheets of felt and then decorate the bag with the fabric crayons and mini pom poms. Perfect for collecting eggs on the Easter Egg hunt !! Each craft kit is delivered in a very pretty yellow organza bag ready for your child to decorate. This Easter Egg bag decorating craft kit is a great creative Easter gift idea for children and will produce a beautiful bag that will be treasured by the family for years to come. Each cotton bag measures approx 23cm x 21cm. Each organza bag measures approx 17cm x 12cm. Recommended for children aged 3 years + due to small parts. Some adult supervision may be required.
French Style Sewing Storage Box
Antiqued style grey/green sewing box with two glass doors and drawer, finished with lace ribbon. Inside: five removable internal compartments, drawer and three removable internal compartments. Length 24cm, Width 24cm, Height 11cm


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Custom Recipes for
Linda's Irish Shepherd's Pie
Muffins are great for breakfast, with coffee, or just as a snack on the go.
Soup is what the doctor ordered to cure those winter blahs.
Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $7.99!
See how to make an amazing shepherd’s pie with a special Irish twist.
See a version of shepherd pie with lamb, mashed potatoes, and Cheddar cheese.
See how to make a shortcut shepherd’s pie with leftover beef.
Read our allrecipes.com blog


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Trust us Bengali cuisine has much more to offer than macher jhol and mutton kosha. These popular delicacies are just a drop in the bucket. As rich and diversified as its culture, Bengali cuisine offers you an extensive range of both veg and non-veg dishes. Yes, you read it right! Bengali food culture includes a wide range of unique veg recipes that leave a strong and flavourful impression on your palate. In fact, if you explore, you will find the list of veg foods is longer than the non-veg ones. And if you are someone who likes playing with flavours, then these dishes are must-try for you! With unique spices and amazing balance of salt and sugar, Bengali vegetarian recipes are just irresistible.
We bring you one such amazing dish called chorchori. It is a quintessential mixed veg sabzi that generally includes potato and different seasonal produce in the recipe. Hence, you will find ingredients varying in different households. But what remains constant and makes the dish unique is the addition of panchphoron - a classic Bengali masala made with 5 spices. A pinch of panchphoron in the recipe makes chorchori standout in the lot. Click here to know more about panchphoron.
How To Make Bengali-Style Chorchori | Chorchori (Bengali-Style Mix Veg) Recipe:
In this particular chorchori recipe, we include vegetables like potato, brinjal, cauliflower and pumpkin. The recipe also includes ginger, garlic, panchphoron, green chilli, bay leaf, coriander leaves, jeera-dhania powder, salt and sugar. Always remember, use mustard oil for this recipe to add that extra zing to chorchori.
All you need to do now is heat mustard oil and add pounded ginger-garlic-green chilli, bay leaf and panchphoron to it. Sauté for a while and add the potatoes. Once the potatoes are half fried add cauliflower and salt to the kadhai and close the lid for a few minutes. Now, add rest of the spices and vegetables to it and mix well till every vegetable piece is well coated with the masala. Close the lid and let the sabzi cook again for a few minutes. Once you get the desired consistency and texture, switch off the flame and transfer the chorchori to a bowl. You may garnish the dish with a spoon of ghee.
Click herefor the step-by-step chorchori recipe (with quantity of the ingredients).
In a quintessential Bengali household, chorchori also gets a non-veg spin with the inclusion of fried fish head to it. You may also add a handful of fried shrimps to the dish.
Pair this Bengali vegetarian delicacy with rice, roti, luchi or paratha and enjoy a soulful meal whenever you feel like. Do not forget to let us know how you like it in the comments section below.
About Somdatta SahaExplorer- this is what Somdatta likes to call herself. Be it in terms of food, people or places, all she craves for is to know the unknown. A simple aglio olio pasta or daal-chawal and a good movie can make her day.


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Tahoe Sierra Board of REALTORS®
C.A.R. recently updated the Legal Tools Quick Reference Guide to now include over 70 different topics addressing key legal issues facing today’s REALTOR®. The all-in-one reference guide also contains each of C.A.R.’s Disclosure Charts and the complete C.A.R. Sample...
With nearly 500,000 California homes worth a combined $268 billion under serious risk from wildfires, and the issue growing more acute with each passing year, insurance companies are ramping up prices or outright refusing to renew policies in fire-prone areas. Use...
October was a busy month for CAR presentations! If you missed any of their economists’ recent outreach presentations, you can review the slides on CAR's Speeches and Presentations page.


Changing a road bike tire can be a pain. It’s always a hassle to get the tire off, put it on, and make sure it’s inflated properly. Plus, there’s the risk of messing up the wheel. This 4 Steps Ultimate Guide on How To Change A Road Bike Tire has everything you need to change your tire in the easiest and safest way possible.
The guide includes everything from the right tools and techniques to ensure a perfect result every time, without any hassle. Finally, no more botched tire changes!
Overview: How To Change A Road Bike Tire in 4 Steps
- Step 1: Removing The Wheel
- Step 2: Remove The Old Tire
- Step 3: Inserting a New Bicycle Tube
- Step 4: Putting Your Tire Back
Every step will be covered in depth. Jump to step by step guide
The Necessary Tools For The Job Are:
Changing your bike tire is best done with the right tools. Here are some of the essential ones you’ll need.
- New tires
- New tubes
- Flat head screwdriver
- Allen key/hex wrench set
- Tire pump
- Cleaning clothes for your hands and tires
How To Change A Road Bike Tire: 4 Easy Steps
- Remove The Wheel
- Remove The Old Tire
- Inserting a New Bicycle Tube
- Putting Your Tire Back on Your Bike
Step 1: Removing The Wheel
The first step in How To Change A Road Bike Tire is removing the wheel.
- Unscrew your quick release levers to loosen.
- Take off the front side of your bike tire.
- Unscrew both nuts on either side of the backside as well.
- Before you move on to shimmying out that wheel from its place in order to remove it.
Step 2: Remove The Old Tire: How To Remove Road Bike Tire?
Before you put a new bicycle tube in, remove the old tire.
- Put the bike in a bike stand or upside down on the ground
- Unscrew the cap from the air valve before pulling it out.
- Use a tire lever to push the tire away from the rim.
- To remove the old tube, you’ll need to un-pinch and separate the cord.
- Remove old tire By Slide your old tube off of the rim
- Clean rim with alcohol then place new tire onto rim
Step 3: Inserting a New Bicycle Tube
- Carefully remove the tube, the dust cap, and lock ring.
- Before removing the tire, inflate the bicycle tube.
- Inspect the inside wall of the tire for a puncture or any other type damage.
- Place the tube inside the tire, and inflate it to check for leaks.
Step 4: Putting Your Tire Back
- Put the air valve in the air hole.
- Put one side of the wheel on top of it.
- Put another side over and seal it with a tire lever to fit it back onto the wheel frame.
- If there is an air valve, screw the lock ring down onto it.
- Inflate your tires to the correct pressure.
- Slide the wheel back onto the bike and replace the levers or nuts.
- Reconnect the brakes to the handlebars if needed.
Why Change Your Road Bike Tires
There are a few reasons to change your road bike tires.
First, if you’re riding in wet or muddy conditions, the tires will become more clogged and less responsive to the pedals.
Second, tire wear can be accelerated by sharp turns or braking heavily on rough roads – changing to a softer tire will help reduce stress on your bike and extend its life.
Finally, over time the tread of a standard road bike tire can start to peel away in patches – replacing them with something that has better grip is, therefore, an effective way of restoring performance and preventing accidents.
Here are some more info: Why Change Your Road Bike Tires
Worn out tread
If your bike’s tread has worn down significantly, it might be time to change the tire. This is especially likely if you’re regularly riding in wet or muddy conditions, as the tread will become clogged and less responsive to the pedals.
Tire wear accelerated by turns or braking
A softer tire can help reduce stress on your bike and extend its life – but it’ll also perform better in these circumstances. If you frequently make sharp turns or brake heavily on rough roads, switching to a softer tire may well be the best course of action for both performance and durability.
Punctures when cycling
A tire that’s been damaged can cause you to lose control of your bike, which can lead to accidents. If this happens to you, it’s always best to replace the tire as soon as possible – even if the damage only seems minor.
If you notice signs of dry-rot on your tire, it’s important to get it fixed as soon as possible. Dry-rot is a fungus that can severely damage tires over time, and can even cause them to burst. If left untreated, the fungus will spread and destroy the entire tire – so don’t wait until it becomes a serious problem before getting help.
How To Change An Inner Tube On A Road Bike?
Change An Inner Tube- 1.Remove the tire
- Deflate the tire entirely
- Detach the old tire
- Removed the inner tube by hand
- Lever the tire out with levers and remove it
- Inspecting for any problems
Change An Inner Tube– 2.Installing a fresh inner-tube
- Inspect the tire for any damage
- If problems can be repaired, do so now with patches or plugs
- Install a new inner tube
- Set up the tire
- Fit the new tube
- Fit the second side of the tire
- Fitting tire with tire levers
- Install new tires and patch it up if necessary.
- Inflate the tire.
- The bike is now ready to ride!
How Long Do Road Bike Tyres Last?
Road bike tires usually last anywhere from 6,000 to 10,000 miles, but this will vary depending on the type of riding that you do and the quality of the tires.
It is important to replace your tires regularly if you are riding on rough terrain or in conditions where there is a lot of debris on the road. The lifespan of a tire can also be shortened by riding on the wrong type of tire for your bike, using the wrong inflation pressure, or over-inflating your tires.
This is because tires are made to perform in a certain way, and if they are not used in the right conditions or with the correct pressure then this can shorten their lifespan.
Read More on How Long Do Bike Tires Last?
How Often To Change Road Bike Tires
This is a difficult question to answer, as the best time to change road bike tires depends on a variety of factors.
When it comes to road biking, most experts recommend changing your tires every 6000 miles. This frequency can be altered depending on the type of terrain you are riding on, the weight of your bike, and your riding style.
To make sure you are getting the most from your cycling experience, it is important to be aware of the various types of tires and their respective characteristics.
There are clinchers, Gators, Tubeless, Tubeless-Ready, and Tubeless-Compatible tires. Each has its own set of benefits and drawbacks that should be taken into consideration before making a purchase.
How To Change A Bike Tire With Disc Brakes?
Changing a bike tire with disc brakes can be a bit tricky, so make sure to follow these simple steps.
- First, remove the wheel and tire from the bike.
- Second, remove the nut that holds the brake caliper in place.
- Third, remove the brake caliper by unscrewing it from the rotor.
- Fourth, take off the old tire and put on the new one.
- Fifth, replace the nut and screw the caliper back on to the rotor.
- Sixth, reinstall the wheel and tire on the bike.
- Seventh, reattach the brake cable.
- Eighth, screw the wheel back onto the frame.
- Finally, reattach the brake lever.
How do you change a road bike tire? (TL;DR)
The first step is to deflate the tire. This can be done by either inflating it with a compressor or using a bike pump. Next, you need to use a flathead screwdriver and insert it into the valve hole at the bottom of the tire.
Once you have inserted the screwdriver, twist it until you hear a click sound. If you are unable to hear this sound, your valve may not be working properly and should be replaced.
Next, remove the needle from its casing on top of the wheel rim and place it inside of the valve hole on top of the tire while pushing down slightly with your thumb or index finger so that it will seat itself inside of its casing. Then, repeat these steps for all four valves located on each side of each wheel rim’s casing (two per side).
This article discusses how to change a bike tire from start to finish with no mistakes. It covers everything from removing old tires, installing new ones, and ensuring there are no difficult parts in between.
It also has tips on how to use compressed air canisters in case of an emergency situation or when you don’t have your own bicycle pump handy.
Changing a bike tire doesn’t seem like such a daunting task after reading this guide!
I hope that by now you feel confident enough about changing your first flat yourself because it’s not as hard as it seems.
How full should bike tires feel?
A full bike tire is when the tire’s treads are flush with the ground. It’s not necessary to fill your tires up completely, but they should be close to being filled in order for them to provide optimum performance.
Can you change bike tires yourself?
It is not recommended to change bike tires by yourself. However, you can do it if you have some basic skills in bicycle repair and if the tire has a slow leak or puncture.
How do you corner on a road bike?
To corner on a road bike, you need to practice. The best way to practice is to ride around on the road with your front wheel turned in at an angle so that it is perpendicular to the direction of travel.
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How To Install Bike Tire Liners
For bike tires that are in need of some help, it may be worth your time and energy to install a tire liner.
This can serve as an inflatable inner tube that will fill with air automatically when you start pedaling or use the hand pump.
Liners for bikes typically come accompanied by a patch kit so that if any punctures do happen while riding around town on them then they’ll be easy enough to fix without any hassles!
The process is very simple
- First off, cut open one end of the package and slide out the liner from inside.
- Once you’ve done this, the next step is to slide it inside your tire.
- Make sure that all of the liner’s air chambers are facing outward and not sticking out since they’ll be needed for pumping.
Next up, take two pieces of tape and fold them over one another so that they form a loop with each other which should be at least four inches long in total length.
Then you place these loops around either end of the punctured tube before sealing everything off using more adhesive strips if necessary.
This will create a sealant from where the holes were which will prevent any further damage or leakage when riding down bumpy roads.
So there we have it! How To Install A Road Bike Tire in five minutes or less.
how to change a road bike tire with co2 ?
The How To Change A Road Bike Tire process is a lot easier when you use a hand pump or CO₂ cartridges.
But in some situations, like if your tire has been punctured by glass for example, it’s better to use mechanical means and find someone with the right tools.
Having a spare pump with you is always the best idea, but if you don’t have one or are in an emergency situation, this next section will teach you how to use compressed air (or “co²”) canisters.
First of all, we’ll need to attach the other end of the tube from our co² canister onto your valve stem and then let it slowly decompress into your tire until it’s inflated.
How do you know when the pressure reaches optimal levels?
Your bike should be able to roll without any resistance on both sides for at least 20-30 feet while maintaining continuous contact with the ground surface.
If there is still too much resistance after that , try one more time and if it is still too much, you may need to pump the tire manually.
- How To Change A Tyre On Your Road Bike
- How to Replace a Bicycle Tire – Wikihow
- How Much Does It Cost To Replace A Bike Tire
- What Size Road Bike Do I Need?
- How to Change Gears on a Road Bike
- Best Beginner Road Bike Under $500
- How To Remove A Bicycle Tire


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When I took the leap of faith to get my kids their first pet, I was stunned by how difficult it was to teach them proper care techniques. I ended up enrolling them in grooming and care classes through my local pet store. While there, we learned a lot of tips and tricks for taking care of many common household pets. I knew that others could benefit from this information, so I decided to create this site to help. Whether you've had family pets for a while or you're getting ready to buy your kids their first, this site can help you be adequately prepared.
Top Reasons to Choose Natural Pet Food for Your Furry Friend
15 November 2023
Western Vs. English Saddles | A Primer For Beginners
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Which Pet Snakes Stay Small?
27 July 2022
4 Tips For Maintaining An Aquarium
3 March 2022


Capital One Financial Corp. (COF.NYSE) will cut about 905 jobs at its originating mortgage and home-equity loans businesses as it exits those businesses.
The McLean, Virginia company will cut at least 768 of those jobs at its 8000 Dominion Parkway in Plano with the rest of the cuts coming in St. Cloud, Minnesota and Melville, New York. In a WARN letter to the Texas Workforce Commission, Capital One said the layoffs would take place around the first of the year.
Capital One will still provide loans for affordable housing and multifamily financing to real estate developers and investors, as well as continue to service its existing home loans portfolio, according to the Bloomberg report.


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MELKSHAM has more patients per GP compared to the average figure for Wiltshire according to the NHS.
And this number looks set to rise with new housing development increasing the town’s population and no current plans to build a new GP surgery in the area.
The figures have been obtained from NHS Digital by Melksham News following concerns that there would not be enough GPs in the town to support Melksham’s growing population if the proposed closure of St Damian’s Surgery had gone ahead.
Despite the application to close St Damian’s being turned down last month by the Wiltshire Clinical Commissioning Group (CCG), figures show that Melksham’s GPs have a higher number of patients compared to others in Wiltshire.
According to the most recent NHS digital figures from September 2018, a full-time equivalent (FTE) GP in Wiltshire has an average of 1,549 patients. In comparison, Giffords Surgery has 1,764 patients per FTE GP, Spa Medical Practice has 1,663 patients per FTE GP; and BoA&MHP (which manages four sites including St Damian’s Surgery in Melksham) has 1,788 patients per FTE GP.
Currently there is no official recommendation for how many patients a GP should have. This is because the demand each patient places on their GP is different – older patients, young children or people with long-term conditions, will need to see their GPs more than others.
No new campus surgery
In recent years there have been hopes that new development and investment in the area would increase medical provision in Melksham.
In 2016 Wiltshire Council announced that a new GP surgery would be part of the Melksham Campus development at the Melksham House site. It was originally planned that St Damian’s Surgery would move into the new building.
However, at this month’s Melksham Area Board meeting, the deputy leader of Wiltshire Council, cllr John Thomson, said that this is no longer the case. “We are still very much open to having a GP surgery on site and there is a site reserved for it,” said cllr Thomson. “We are in talks with them (Wiltshire CCG) at the moment, but there is no commitment from the health service to actually fund a building and build one on site.”
Finance & business manager of BoAHMP, who manage St Damian’s Surgery, Ellen Wilson, confirmed to Melksham News, “BoAHMP have no plans to move into the Melksham Campus space, at this point in time. Wiltshire CCG is considering the long term GP space requirements in Melksham and are aware of the planned new housing developments, which is why the site remains earmarked as such on the Melksham Blue Pool site.
“Spa, Giffords & BoAMHP practices continue to work to join up other patient services in the Melksham locality through networks, working together to deliver care to our patients, in line with the NHS 10-year vision. It is possible that the Melksham Campus GP surgery space may form part of this new way of working, but it is far too early at this stage to comment further.”
Wiltshire CCG plans
In response to questions from Melksham News about what is being done to ensure there is an adequate number of GPs serving Melksham, a spokesperson from the Wiltshire CCG said, “Wiltshire Clinical Commissioning Group is committed to ensuring that healthcare services are delivered in a way that meets the needs of people right across Wiltshire.
“We are working closely with the three GP surgeries in Melksham to ensure resilient primary care services remain available to the local community. This will include working with patients, the public and town officials to improve the understanding, relationships and branding of primary care services in Melksham.
“The development of Primary Care Networks is a key way forward for managing demand for GP services across the country, as set out in the NHS Long Term Plan. The current and future needs of Melksham will be considered as part of this programme of work in Wiltshire.”


WASHINGTON - President Bush emerged from a meeting with foreign financial officials on Saturday and pledged a global response to the credit crisis that will lead toward a "path of stability and long-term growth."
Bush announced no new strategies to attack the economic woes circling the globe, stressing instead, "We will do what it takes to resolve the crisis and the world's economy will emerge stronger as a result."
The president spoke in the Rose Garden outside the White House, joined there in a show of solidarity not long after daybreak by finance officials from the so-called G-7 - Japan, Germany, Britain, France, Italy and Canada, in addition to the United States. Treasury Secretary Henry Paulson and Secretary of State Condoleezza Rice also attended.
"The United States has a special role to play in leading the response to this crisis," the president said. "That is why I convened this morning's meeting here at the White House and it is why our government will continue using all the tools at our disposal to resolve this crisis."
He added, "As our nations carry out this plan, we must ensure that the actions of one country do not contradict or undermine the actions of another. In an interconnected world, no nation will gain by driving down the fortunes of another. We are in this together. We will come through it together."
Bush's comments were aimed at avoiding the mistakes that worsened economic conditions during the Great Depression in the 1930s. Then, some nations pursued go-it-alone strategies such as erecting protectionist trade barriers to shield their domestic industries. Those trade barriers ended up only worsening the global downturn.
In the current crisis, Ireland moved to guarantee all bank deposits, a decision that triggered similar actions in Germany and other nations which were concerned that nervous depositors would move their bank accounts to Ireland.
The White House meeting lasted about a half-hour, less than scheduled.
An even larger Group of 20 countries - which include the wealthiest and the world's biggest developing nations such as China, Brazil and India - arranged a meeting with Paulson later in the day.
It was the 21st time in 26 days that the president has spoken publicly about the credit crisis gripping the financial markets, a crisis that has now infected the stock markets. Congress heard testimony last week that the retirement accounts of Americans have lost $2 trillion in the past 15 months, and the New York Stock Exchange Dow Jones industrials average plummeted more than 18 percent last week alone, the largest ever in a week.
A wave of selling sent markets lower in several Asian and European nations Friday, while other exchanges were closed to prevent the same fate.
The stock selloffs stem from fears that banking systems have essentially frozen up around the world - a credit crisis that took hold sharply three weeks ago in the United States and has led to an escalating series of interventions by the administration and Federal Reserve.
It was only eight days ago that Congress approved a $700 billion bailout for the financial industry, and the Fed has pumped billions of dollars into the economic system hoping to provide greater access to credit for potential borrowers.
On Friday, Paulson announced the Treasury would begin buying part ownership in American banks, the first time the government has taken such action since the Depression of the 1930s.
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