text:
Basket oval shape with a high handle woven from natural willow vines, nothing painted. The bottom is smooth, made of fiberboard.
The height of pens you can make any, or without it entirely )
The upper edge of the basket is decorated with plaited willow twigs.
The basket is designed to:
- registration it a gift set
- floral arrangement of flowers
A basket of willow twigs will add in Your interior comfort and warmth.
fully handmade. The basket can be painted or decorate according to your taste )
Can make according to Your designs and sizes.
How to keep
If necessary, wipe with a dry or slightly damp cloth or brush, allow to dry. Not to throw.


text: Strudel with poppy seeds is a product which is by regulations of a quality of grains, milling and bakery products, pasta and fast frozen dough (Official Gazette no. 52/95 and Og. SCG no. 56/2003. - Dr. Rule book and 4/2004. Dr. Rule book). Strudel with poppy is in properly formed shape with the weight of 200gr. Finished baked product that does not require any surgery before eating during the sale. Color of the product is pretty ruddy without the smell, crust is bright and well balanced. Roll shape of the product is clearly visible at the intersection. Fine porous structure, sufficient filling. Poppy seed filling is in appropriate color, distributed equally in the product. Expressed pleasant aroma of poppy seeds. Typical melting for this kind of product.

domain: food


text:
But there’s still a very long way to go before men and women are viewed equally by employers – many of whom still act as if mothers have an inalienable right (and perhaps duty?) to time off to look after their baby, while viewing fathers who want to play an active caring role as 'slackers'.
Interestingly, almost half (44 per cent) of 750 working fathers surveyed by Cityfathers, a new fathers' network, said missing their children was their biggest daily challenge, yet almost a third (29 per cent) had either taken no paternity leave or did not take their full entitlement.
This is not because new fathers don’t want to be involved. We know that many of those dads who don’t take the leave find other ways to take time off when their children arrive. We also know, from research on parenting leave around the world, that employer culture has a huge influence on fathers’ take-up of paternity and other parental leave.
As outlined in the Fatherhood Institute’s latest paternity leave research summary, this is about a whole host of factors, ranging from attitudes towards long-hours working, commitment to gender equality and caring values, to dads’ perceptions of support – or the lack of it – from top managers.
It’s also worth remembering that for many dads – still more likely to the family’s sole or main breadwinner – the level at which leave is paid remains a big issue. Statutory paternity pay comes at just £136.78, or 90 per cent of your average weekly earnings (whichever is lower) – which is less than the minimum wage.
Unfortunately, Mr Clegg’s changes will have only a marginal impact on all this.
Under the new ‘shared parental leave’ regime, mothers who want to return to work before their maternity leave finishes will be able to gift the remaining leave to the child’s father, or share it with them in chunks.
Only around a third of working families are likely to be eligible for this added flexibility, since both mum and dad will need to have worked for their respective employers continuously for 26 weeks at the 15th week before the expected week of childbirth.
For some eligible families, where mum is the high earner and dad is in a steady, lower paid job, it could work well. But parents will have to plan and negotiate their use of the leave carefully, and how many parents will feel safe enough to risk it remains to be seen. The government estimates 4-8 per cent take-up.
Crucially, even those families who do end up sharing the leave will be trailblazing within a system in which responsibility for childcare remains firmly in the hands of mothers – because the Coalition’s ‘shared parental leave’ is, in fact, transferable maternity leave. Fathers themselves gain no additional, independent entitlement to take time off to care.
And that, despite today’s clarion call for change from Mr Clegg, means there will be little to stop employers continuing to treat men and women in the workplace as two different species.
Jeremy Davies is a journalist specialising in health and social policy. A father of one, he works for the Fatherhood Institute and does some teaching at the University of Manchester

domain: sociology


text:
The Alapaha Blue Blood Bulldog is a unique and captivating breed with a fascinating history. In this complete guide, we will explore everything you need to know about this breed, including its origin, physical characteristics, temperament, health, and training. Our goal is to help you understand what makes the Alapaha Blue Blood Bulldog such a special companion and how to provide the best possible care for your dog.
|Medium-sized breed; males: 20-24 inches, females: 18-22 inches
|Males: 70-90 pounds, females: 55-75 pounds
|Short, dense, and close-fitting
|Blue merle, brown merle, black, brown, brindle, and white
|Loyal, protective, friendly, intelligent, and alert
|Esperanza de vida
|Moderate; daily walks and playtime
|Intelligent, trainable breed; requires consistent, positive reinforcement methods
|Common Health Issues
|Hip dysplasia, entropion, deafness, skin allergies
Size and Weight
The Alapaha Blue Blood Bulldog is a medium-sized breed, with males standing between 20 to 24 inches tall and females measuring between 18 to 22 inches. Males typically weigh between 70 and 90 pounds, while females weigh between 55 and 75 pounds. Their sturdy and muscular build gives them an imposing presence.
Coat and Color
The Alapaha Blue Blood Bulldog’s coat is short, dense, and close-fitting to the body. It is smooth to the touch and requires minimal grooming. This breed comes in a variety of colors, including blue merle, brown merle, black, brown, brindle, and white, often with white markings on the face, chest, and legs.
One of the most striking features of the Alapaha Blue Blood Bulldog is its expressive eyes, which can range from light blue to dark brown. They have a broad head with a square-shaped muzzle, and their ears are typically medium-sized and folded over. Their strong, muscular body is well-balanced and agile, making them an impressive athlete.
Esperanza de vida
The average life expectancy of an Alapaha Blue Blood Bulldog is between 12 and 15 years. With proper care, including a healthy diet, regular exercise, and routine veterinary check-ups, they can live long, happy lives.
Temperamento y personalidad
The Alapaha Blue Blood Bulldog is known for its loyalty, protective instincts, and friendly nature. They are confident, intelligent, and alert, making them excellent watchdogs. They are also affectionate and gentle with their family members, often forming strong bonds with their owners.
Socialization with Other Animals
Early and consistent socialization is crucial for the Alapaha Blue Blood Bulldog to develop a well-rounded temperament. With proper socialization, they can get along well with other dogs and animals, but their natural protective instincts may make them wary of unfamiliar animals. Introducing them to a variety of different animals and situations early in their life will help them become more adaptable and accepting.
Interaction with Children
Alapaha Blue Blood Bulldogs are generally good with children, especially if they are raised together. They are patient and gentle with kids, but due to their size and strength, it is essential to supervise interactions between the dog and young children. Teaching children how to interact safely and respectfully with the dog is equally important.
Inteligencia y capacidad de formación
Alapaha Blue Blood Bulldogs are intelligent dogs with a strong desire to please their owners. This makes them highly trainable, as long as consistent, positive reinforcement methods are used. They respond well to praise and rewards and early training will help them grow into well-mannered and obedient companions.
Energy Level and Exercise Needs
This breed has a moderate energy level, requiring daily exercise to keep them physically and mentally stimulated. Regular walks, playtime in the yard, and interactive toys are excellent ways to keep your Alapaha Blue Blood Bulldog engaged and happy. Providing them with a combination of physical and mental activities will prevent boredom and ensure a balanced, well-adjusted dog.
Health Issues and Care
Common Health Problems
While the Alapaha Blue Blood Bulldog is generally a healthy breed, it can be prone to certain health issues, such as hip dysplasia, entropion, deafness, and skin allergies. Regular veterinary check-ups and early detection can help manage these issues and ensure the best possible care for your dog.
To maintain your Alapaha Blue Blood Bulldog’s health, it’s essential to take preventative measures. Providing a balanced diet, regular exercise, and keeping up-to-date with vaccinations and parasite prevention will go a long way in keeping your dog healthy. Additionally, monitoring your dog for any unusual behavior or symptoms can help you catch potential health issues early on.
Routine Veterinary Care
Routine veterinary care is crucial for the well-being of your Alapaha Blue Blood Bulldog. Regular check-ups, vaccinations, and dental care will ensure your dog stays in the best possible health. It’s also essential to establish a good relationship with your veterinarian, who can guide you through any health concerns or questions you may have about your dog.
Diet and Nutrition
Feeding your Alapaha Blue Blood Bulldog a balanced and nutritious diet is essential for their overall health. High-quality dog food, whether commercially prepared or homemade, should be tailored to your dog’s age, weight, and activity level. Consult your veterinarian for guidance on the appropriate diet and portion sizes for your dog.
Grooming and Hygiene
The Alapaha Blue Blood Bulldog’s short coat requires minimal grooming, but regular brushing will help remove loose hair and keep their coat healthy. Bathe your dog as needed, using a mild dog shampoo to prevent skin irritation. Additionally, trim their nails regularly, check their ears for signs of infection, and brush their teeth to maintain good dental health.
Training and Socialization
Obedience training is essential for the Alapaha Blue Blood Bulldog, as it helps establish a strong bond between you and your dog and ensures they are well-behaved in various situations. Start training your dog at an early age, using positive reinforcement techniques, and be consistent and patient in your approach.
Socialization with Other Dogs
Socializing your Alapaha Blue Blood Bulldog with other dogs is important for their overall development. Expose them to different breeds and sizes of dogs, both in controlled environments like puppy classes and in public settings like dog parks. Regular socialization will help them become more comfortable and confident around other dogs.
Addressing Problem Behaviors
If your AlapahaBlue Blood Bulldog exhibits problem behaviors, such as excessive barking, digging, or aggression, it is essential to address these issues as soon as possible. Consult a professional dog trainer or behaviorist for guidance on managing and correcting these behaviors. Early intervention and consistent training will help prevent these issues from becoming long-term habits.
Crate Training and Housebreaking
Crate training and housebreaking are essential components of raising a well-behaved Alapaha Blue Blood Bulldog. Introduce your dog to their crate early on, making it a comfortable and safe space for them. Consistent crate training can help with housebreaking and prevent separation anxiety. Establish a routine for bathroom breaks and reward your dog for successfully eliminating outside.
Agility and Advanced Training
The Alapaha Blue Blood Bulldog’s intelligence and athleticism make them well-suited for advanced training, such as agility, tracking, or obedience competitions. These activities can provide mental and physical stimulation for your dog while strengthening the bond between you and your furry friend. Look for local dog clubs or training centers that offer classes or workshops in these areas.
Living with an Alapaha Blue Blood Bulldog
Ideal Home Environment
The ideal home environment for an Alapaha Blue Blood Bulldog is one that provides them with ample space to move around and a secure, fenced yard for exercise. They can adapt to living in an apartment, provided they receive adequate daily exercise and mental stimulation. The Alapaha Blue Blood Bulldog thrives in a loving, structured home where they receive consistent training, socialization, and affection from their family.
Exercise and Activity Requirements
To keep your Alapaha Blue Blood Bulldog happy and healthy, ensure they receive daily exercise and playtime. Regular walks, interactive games, and off-leash play in a secure area are great ways to keep your dog engaged and active. Providing mental stimulation through puzzle toys or training sessions will also help prevent boredom and encourage good behavior.
Affection and Bonding
Alapaha Blue Blood Bulldogs are known for their loyalty and strong bonds with their owners. They require regular affection and interaction with their family to maintain a happy and well-adjusted temperament. Spending quality time with your dog, whether through play, training, or cuddling, will help strengthen your relationship and create a lifelong bond.
Separation Anxiety and Managing Alone Time
Some Alapaha Blue Blood Bulldogs may experience separation anxiety when left alone for extended periods. To prevent this, gradually acclimate your dog to being alone and provide them with a comfortable, safe space, such as a crate or a designated room. Interactive toys or puzzle feeders can help keep your dog occupied and reduce anxiety while you’re away.
How to Find an Alapaha Blue Blood Bulldog
Choosing a Reputable Breeder
When looking for an Alapaha Blue Blood Bulldog, it’s essential to choose a reputable breeder who prioritizes the health and well-being of their dogs. Ask for references, visit the breeder’s facility, and meet the parent dogs to ensure they are well-cared-for and display good temperaments. A responsible breeder will provide you with health records, genetic testing results, and other relevant information about your potential puppy.
Adoption and Rescue Options
Adopting an Alapaha Blue Blood Bulldog from a rescue organization is another option for finding your new best friend. Rescue groups often have dogs of various ages, including puppies and adults, looking for loving forever homes. Adoption can be a rewarding experience, as you provide a second chance for a dog in need. Research rescue organizations specializing in Alapaha Blue Blood Bulldogs or similar breeds, and be prepared to undergo an application process and home visit before adoption.
Preparing for a New Puppy
Before bringing your new Alapaha Blue Blood Bulldog puppy home, ensure you have all the necessary supplies, including a crate, bed, food, water dishes, toys, grooming tools, and a leash and collar. Puppy-proof your home by removing potential hazards and creating a safe environment for your new dog. Familiarize yourself with puppy care basics and establish a routine for feeding, exercise, and training.
Cost Considerations and Budgeting
Owning an Alapaha Blue Blood Bulldog comes with various expenses, including the initial cost of the puppy, veterinary care, food, grooming supplies, and training classes. Be prepared to budget for these costs and consider pet insurance to help with unexpected veterinary expenses. Investing in the well-being of your dog will ensure a healthy, happy life together.
The Alapaha Blue Blood Bulldog is a loyal, protective, and affectionate breed that makes a wonderful companion for the right family. Understanding their unique needs and providing proper care, training, and socialization will ensure a strong bond and a happy life with your dog. This complete guide aims to equip you with the knowledge and tools to make the most of your journey with your Alapaha Blue Blood Bulldog and enjoy a loving, lifelong relationship.

domain: pet


SMC® IZN10-11P07 High Frequency AC Nozzle Ionizer With 1/4 in Port, 3 m Power Supply Cable, 21.6 to 26.4 VDC, Corona Discharge, PNP Output, 0 to 55 deg C, ABS/Stainless Steel
The IZN10 is SMC® nozzle ionizer. The nozzle ionizer emits an air-assisted cone of static eliminating ions for focused targets up to 500 mm/20 in. The nozzle can be used with an optional sensor and monitor to suspend emission when static elimination is complete. Available with high flow or energy saving nozzles. The cartridge can be removed for needle cleaning or replacement. Slim, compact design is suitable for installation in tight spaces.


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ACTIONS > WORDS
Politicians make a lot of promises.
They're supposed to work for you and transparency is the only way to keep them honest.
We've linked to the Congressional Roll Call so that you can see what your elected officials stand for and if they're really working for you.
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text:
Woman to Woman is a little slice of sociology.
Our video film review finds today’s host, Marie Juliette Steinsvold, a French filmmaker and writer; and our panelist, Valerie Peterson, an author and writer; chatting it up at the iconic soul food restaurant, The Pink Teacup in Chelsea about the insightful online documentary, Woman to Woman.
Listen to this review online here.
Veronique Doumbe and Malika Franklin, are the mother and daughter team who come together to direct the online documentary, Woman to Woman. With their unique concept, they take the topic of raising teenage daughters in New York City to enlightening heights. Completely multicultural, we are introduced to a beautiful cast of eclectic New Yorkers who also happen to be mothers and daughters. They are outspoken and individualistic in their opinions and approaches to living and growing up in a city with much to offer and much to consider each and every day.
The evolution of conversation between the women and women-to-be provides a nice arc. Since there is little narrative, the razor sharp editing creates a strong and often funny dialogue. Shot in the spring and summer, New York City is visually stunning as a backdrop and becomes a character all of its own. This is an admirable film that is handmade to become a vehicle for great discussions and dialogue as well as a support resource on the subject matter. It also fosters the understanding that in spite all of our differences, our concerns for those we love and care for are one in the same.
If you have a film you would like to have reviewed, contact us at firstname.lastname@example.org.

domain: artistic


text:
Invite a friend
Watershed Plan Meeting
- Find out about the Small Watershed Action Plan (SWAP) now underway in the Dundalk area
- See how a SWAP will improve your community, and water quality in Bear Creek/Old Road Bay
- Get updates on current conditions in the watershed
- Vote on actions to take to protect and restore the watershed
The plan, sponsored by Baltimore County Department of Environmental Protection and Sustainability (EPS) and the Dundalk Renaissance Corporation, will guide restoration efforts in the watershed to improve water quality in local streams and the Chesapeake Bay.
|Where||North Point Library 1716 Merritt Blvd, Baltimore, MD 21222 (Meeting Room)|
|Next on||This event is over.|
|Time||6:00 pm–8:00 pm|
|Who to bring||Everyone|
More About North Point Library
North Point Library is a local branch of the Baltimore County Public Library. It carries a variety of books, DVDs and other resources such as encyclopedias, reference materials, fiction and more. The library has internet-enabled computers available for public use and offers computer classes. In addition, the library provides programs including homework help, computer assistance for job seekers, knitting groups, story time, book groups and more. The location also has a meeting room for 100 people.

domain: geography


text:
Beautiful Taylor plan has beautiful details and a balcony off the mastered suite.
Directions from the Builder
I95 to exit 106 (Jimmy Deloach Blvd). Go about 2 miles west on Jimmy Deloach Blvd, turn right onto Benton Blvd. Follow Benton Blvd to the end, turn left onto Highland Blvd. Follow Highland Blvd. about 5 miles, Cumberland Point on the left.


text:
It’s been another great month at Big River Tattoo! Thanks everyone who stopped in to get tattooed. Here are some of the tattoos from this month. Send an email to email@example.com to schedule an appointment. Keep those ideas coming!
Rich will be working at New York Adorned every Tuesday in August! If any of our clients have been waiting for Rich to come out that way, now is your chance. Email firstname.lastname@example.org or email@example.com to schedule an appointment!
June is coming to an end so we just wanted to show case a few of the tattoos that were done this month at the shop by both Rich Cahill and Mike Gary. We’ve had a lot of really wonderful clients this past month and we are looking forward to July. Bring on the awesome tattoo ideas!
Karen Glass came out from Brooklyn to hang out with us on Wednesday (June 14th) and spent the day as our guest artist. It was great having Karen with us at the shop! She spent the day working on beautiful floral tattoos. Check out the tattoos she did during her stay:
Check out more of Karen’s work on her instagram: https://www.instagram.com/karenglasstattoo/
Walk-ins are more than welcome at Big River Tattoo. If you’re looking to pop by for a tattoo, we would be happy to help you out! Starting in June, Rich will be taking walk-ins on Sundays and Mike is always happy to hook you up with a tattoo if he has the time. Come by and chat with our artists. We have flash on the walls to pick from and we can draw something up for you too.
We have walls full of vintage flash that are perfect for walk-in tattoos. We would love for you to pick one out!
Big River Tattoo is home to a large collection of vintage flash. Rich recently put up new flash, filling the rest of the entranceway. We are proud to display flash by Bart Bingham, Paul Rogers, Jensen Detroit, Bill Loika, Lee Roy Minugh, Owen Jensen, L.L. McKeevey, Herbert Hoffman, Horiyuki (Jill Bonny), and Colin Laroque. We have a little bit of everything and we would love to tattoo these pieces, so feel free to pick one off the wall!
Dan Santoro joined us yesterday at Big River Tattoo and spent the day tattooing at the shop. It was great having him here! Dan was booked all day with his bold, traditional tattoos.
16 years ago, Rich took Dan as his apprentice and got him started in the world of tattooing. It was great for the two artists to work along side each other again. We’re looking forward to having Dan guest spot at Big River Tattoo again in the future!
Check out Dan’s work on his instagram @dan_santoro
Rich will be tattooing at The Prestige Tattoo and Music Festival Saturday, May 6th and Sunday, May 7th. The festival is being held at The Fillmore at 29 E. Allen St, Philadelphia, PA.
There will be amazing artists and great bands all gathered in one place! The show holds a high standard of quality over quantity and they are very proud of the artists they have hand picked for the event. Rich is stoked to be selected to be a part of this.
Tickets are available separately or bundled together. It will be sold as 25$ a piece, or 40$ for the bundle. The first 250 single tickets will be sold for 20$ a piece. Click this link to purchase tickets Ticket Master
Also, Eric Perfect, who will also be tattooing at The Prestige, recently interviewed Rich. Check it out here:
Rich has been trying to get out to Colorado and is stoked that he will finally be making out there and will be doing a guest spot at Lifetime Tattoo Denver! Rich will be at Lifetime Tattoo from April 25th-27th. If would like to get something done, please send an email to firstname.lastname@example.org.


Shenzhen Minghao gloves Co., Ltd was established in 2011. It is a comprehensive enterprise integrating R&D,design,production,trade and sales. We always committed to R&D and innovation of high-quality gloves of various categories, and adhere to the independent production line. Its main products: anti cutting gloves, anti-static gloves, heat resistant gloves, conductive gloves, game fingertips, dust-free gloves, PU coated gloves, plastic dot anti-skid gloves, oil-proof and acid-base resistant gloves, cotton electronic gloves, garden gloves, beauty etiquette gloves and other high-quality gloves.
By the end of May 2021, Minghao's high-quality products have been exported to nearly 200 countries and regions...
Quality is the life of the brand, and higher satisfaction is the starting point of our dignity
Corporate image is the core of corporate culture construction
Quality - the eternal way to win


text:
Within several days of it’s release, “Slow” has been Charting on AMAZON starting from #52 in Contemporary R&B and peeking at #2. Also it has been charting on the Amazon Hot New Releases starting at #7 and peaking at #1. Isaiah and his Record “Slow” are a favorite with the ladies & music lovers in general. It has a smooth, rhythmic & catchy chorus with a Fresh Lyrical edge that the young generation appreciates. BSE Recordings is Proud to have Isaiah represent the ever-growing Label. BSE’s Artist Arika Kane says ” Isaiah is very talented. He is a producer & songwriter as well, I look forward to seeing him take advantage of all the Facets of being an Independent Artist, and creating his own Future. With his talent & his drive, He is going to go very far and his future in Music is bright ! ” Isaiah will soon be recording his Album, and will be on his Promo Tour in 2013 & Music will never be the same…..Look Out for ISAIAH !
New and Talented BSE Recording Artist ISAIAH releases his Debut Single "SLOW" on April 2nd 2013. In a week this sultry, smooth Urban/Pop Song has been a favorite already, especially with the Ladies. Charting #52 in Amazon Contemporary R&B, and moving up to #27 5 days after its Release. "SLOW" has also charted #8 in R&B Hot New Releases. Spread the word about ISAIAH & the refreshing sound that he creates ! A Rising Star for sure, and if you miss feel good Music that Ladies want to hear & enjoy... you will Love what ISAIAH has to offer. Stay Tuned !! www.bserecordings.com DOWNLOAD "Slow" by ISAIAH Right Here... http://www.amazon.com/Slow/dp/B00C69BY5S/ref=zg_bs_195422011_27

domain: entertainment


text:
Earth sensing: from ice to the Internet of Things
The evolution of technology has led to improvements in our ability to use sensors for earth science research. Radio communications have improved in terms of range and power use. Miniaturisation means we now use 32 bit processors with embedded memory, storage and interfaces. Sensor technology makes it simpler to integrate devices such as accelerometers, compasses, gas and biosensors. Programming languages have developed so that it has become easier to create software for these systems. This combined with the power of the processors has made research into advanced algorithms and communications feasible. The term environmental sensor networks describes these advanced systems which are designed specifically to take sensor measurements in the natural environment.
Through a decade of research into sensor networks, deployed mainly in glaciers, many areas of this still emerging technology have been explored. From deploying the first subglacial sensor probes with custom electronics and protocols we learnt tuning to harsh environments and energy management. More recently installing sensor systems in the mountains of Scotland has shown that standards have allowed complete internet and web integration.
This talk will discuss the technologies used in a range of recent deployments in Scotland and Iceland focussed on creating new data streams for cryospheric and climate change research.
Cynthia Chandler, Woods Hole Oceanographic Institution
The scientific research endeavor requires data, and in some cases massive amounts of complex and highly diverse data. From experimental design, through data acquisition and analysis, hypothesis testing, and finally drawing conclusions, data collection and proper stewardship are critical to science. Even a single experiment conducted by a single researcher will produce data to test the working hypothesis. The types of complex science questions being tackled today often require large, diverse, multi-disciplinary teams of researchers who must be prepared to exchange their data.
This 2016 AGU Leptoukh Lecture comprises a series of vignettes that illustrate a brief history of data stewardship: where we have come from, how and why we have arrived where we are today, and where we are headed with respect to data management. The specific focus will be on management of marine ecosystem research data and will include observations on the drivers, challenges, strategies, and solutions that have evolved over time. The lessons learned should be applicable to other disciplines and the hope is that many will recognize parallels in their chosen domain.
From historical shipboard logbooks to the high-volume, digital, quality-controlled ocean science data sets created by today’s researchers, there have been enormous changes in the way ocean data are collected and reported. Rapid change in data management practices is being driven by new data exchange requirements, by modern expectations for machine-interoperable exchange, and by the desire to achieve research transparency. Advances in technology and cultural shifts contribute to the changing conditions through which data managers and informatics specialists must navigate.
The unique challenges associated with collecting and managing environmental data, complicated by the onset of the big data era, make this a fascinating time to be responsible for data. It seems there are data everywhere, being collected by everyone, for all sorts of reasons, and people have recognized the value of access to data. Properly managed and documented data, freely available to all, hold enormous potential for reuse beyond the original reason for collection.
Dawn Wright, Environmental Systems Research Institute
Director of Models and Data at the UK National Centre for Atmospheric Science, Professor of Weather and Climate Computing at the University of Reading, and the Director of the STFC Centre for Environmental Data Archival (CEDA).
The grand challenges of climate science will stress our informatics infrastructure severely in the next decade. Our drive for ever greater simulation resolution/complexity/length/repetition, coupled with new remote and in-situ sensing platforms present us with problems in computation, data handling, and information management, to name but three. These problems are compounded by the background trends: Moore’s Law is no longer doing us any favours: computing is getting harder to exploit as we have to bite the parallelism bullet, and Kryder’s Law (if it ever existed) isn’t going to help us store the data volumes we can see ahead. The variety of data, the rate it arrives, and the complexity of the tools we need and use, all strain our ability to cope. The solutions, as ever, will revolve around more and better software, but “more” and “better” will require some attention.
In this talk we discuss how these issues have played out in the context of CMIP5, and might be expected to play out in CMIP6 and successors. Although the CMIPs will provide the thread, we will digress into modelling per se, regional climate modelling (CORDEX), observations from space (Obs4MIPs and friends), climate services (as they might play out in Europe), and the dependency of progress on how we manage people in our institutions. It will be seen that most of the issues we discuss apply to the wider environmental sciences, if not science in general. They all have implications for the need for both sustained infrastructure and ongoing research into environmental informatics.
Simon Cox is a Senior Principal Research Scientist at CSIRO. He trained as geophysicist, with a PhD in experimental rock mechanics from Columbia (Lamont-Doherty) following degrees in geological sciences at Cambridge and Imperial College London. He came to Australia for a post-doc with CSIRO, and then spent four years teaching at Monash University in Melbourne where he first began using GIS. Returning to CSIRO in Perth in 1994 to work on information management for the Australian Geodynamics CRC, he moved its focus for reporting onto the emerging World Wide Web, deploying a web-mapping system for Australian geology and geophysics in 1995. The challenge of maintaining the AGCRC website led to metadata-based systems, and Simon’s engagement with the standards community when he joined the Dublin Core Advisory Council.
Work on XML-based standards for mineral exploration data led on to foundation of the GeoSciML project in collaboration with a number of geological surveys. An interest in tying these into broader interoperability systems led to engagement with the Open Geospatial Consortium, where he co-edited the Geography Markup Language (GML) v2 and v3. In OGC he developed Observations and Measurements as a common language for in situ, ex situ and remote sensing, going on to become an ISO standard, and forming the basis for operational systems in diverse fields including air-traffic, water data transfer and environmental monitoring applications. In 2009-10 he spent a year as a senior fellow at the EC Joint Research Centre in Italy working on integration of GEOSS and INSPIRE. He served on the council of the IUGS Commission for Geoscience Information and the International Association for Mathematical Geosciences. In 2006 he was awarded OGC’s highest honor, the Gardels medal. He has been a member of AGU since 1982. Simon is currently based in CSIRO Land and Water in Melbourne, working on a variety of projects across environmental informatics and spatial data systems.


text:
The event of a thread, Art Installation by Ann Hamilton
This large-scale multimedia installation invites an interactive audience to revisit their playful childhood and ride the 42 swings that have been set up. The 55,000-square-foot space boasts a giant billowing white curtain that separates the hall. The towering curtain is, in fact, controlled by the back and forth swaying motion of people on swings. In addition to the swing-controlled curtain, there are stacks of cages containing 42 homing pigeons and a station at which two readers speak into microphones. The text they are reading imparts knowledge that guests to the exhibit are free to choose to listen to. There is also a station where the artist herself is positioned, viewing the entirety of the exhibit through a mirror.


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VIRGINIA BEACH — Two teens were in a car that crashed into a tree just after midnight Sunday, leaving one of them dead and another in jail.
The driver was heading north on Avalon Avenue near Normandy Avenue in a 1999 Oldsmobile when he hit a tree. His 16-year-old passenger, Joseph Fonseca, died at the scene. He was a student at Kempsville High School.
The driver was taken to the hospital with non-life-threatening injuries then booked at the juvenile detention center. He is being charged with driving under the influence and involuntary manslaughter. The case is still under investigation by the police department's fatal accident crash team, the spokesman said.
— Samieh Shalash,

domain: news


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We're getting the sense that you and the Let's Be Fringe Teal Shawl are going to be inseparable! This exquisite shawl is designed to be your go-to accessory, adding an air of wanderlust and boho chic to your everyday outfits. Crafted from a soft and cozy knit fabric, this shawl wraps you in comfort while allowing for a graceful, flowing drape. It's the perfect companion for breezy days or cooler evenings when you need an extra layer of warmth. Versatile and lightweight, it effortlessly elevates your style, making it suitable for casual outings, festivals, and cozy nights by the fire. One of the standout features of this shawl is the fringe along the hem. These whimsical fringe details add a playful element to your look, swaying gently as you move. They contribute a sense of movement and dynamism to your outfit, making it perfect for dancing, twirling, or just embracing the carefree spirit of boho fashion!
Garment Measurements in Inches:
One Size | Length 38”


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Local news sources in Kerela, India, reported this week that eleven people were arrested for allegedly abducting a young man whom they claimed was involved in a fraudulent bitcoin-related scheme.
The young man named Mohammed Nawaz had allegedly convinced people within the region to invest in a crypto-related scheme, dubbed “Bitcoin Network Investment,” which was later discovered to be a scam according to the report.
The investment fraud caused the people of the state to lose their money, which was about $200,320 in total. Victims of this unfortunate incident then took laws into their hands and instructed goons to kidnap Nawaz after realizing he had duped them.
The report further revealed that the hired goons got arrested by the police, after which Nawaz agreed to sell off his assets and make refunds to every victim who had invested their money into the fraudulent scheme.
Meanwhile, Kerala being the state with the highest population of literates in India has revealed earlier this year, its plan to train 20,000 blockchain professionals. The state-backed Kerala Blockchain Academy (KBA) in September piloted a program on the concept of using blockchain to secure the issuance of educational certificates.
The Bitcoin Hideout
Even as cryptocurrencies like Bitcoin continue the march towards mass adoption, fraudsters continue to use the new tool as an opportunity with crypto scams with new styles adopted every day.
In another crypto-related crime update, Coinfomania reported on the recent arrest of Nigerian cybercrime lord, Olalekan Jacob Ponle, popularly known as Woodberry. Woodberry allegedly stole millions of dollars worth of funds from U.S companies and then converted a portion of his loot ($15 million) into bitcoins.
Unfortunately, the FBI confirmed that the stolen funds might not be recovered as a result of the sophisticated nature of the Bitcoin network
Your crypto deserves the best security. Get a Ledger hardware wallet for just $79!

domain: finance


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Bookmark our site, share it with your friends and enjoy watching TV Series and movies online.
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Katniss Everdeen has returned home safe after winning the 74th Annual Hunger Games along with fellow tribute Peeta Mellark. Winning means that they must turn around and leave their family and close friends, embarking on a “Victor’s Tour” of the districts. Along the way Katniss senses that a rebellion is simmering, but the Capitol is still very much in control as President Snow prepares the 75th Annual Hunger Games (The Quarter Quell) – a competition that could change Panem forever.


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Objective: The objective of this study was to evaluate the impact of once- versus twice-daily dosing of perphenazine, which has a plasma half-life of 8-12 hours, on clinical outcomes in patients with schizophrenia. Method: Data from phase 1 of the Clinical Antipsychotic Trial of Intervention Effectiveness (CATIE) conducted between January 2001 and December 2004 were used in this post hoc analysis. Patients with schizophrenia (DSM-IV) randomly allocated to treatment with perphenazine were also randomly assigned to once-daily (N = 133) or twice-daily (N = 124) dosing and followed over 18 months. Discontinuation rate and time to discontinuation were used as primary outcomes to compare the 2 groups. The following clinical outcomes were analyzed as secondary measures: efficacy - Positive and Negative Syndrome Scale, Clinical Global Impressions-Severity scale, Calgary Depression Scale for Schizophrenia, and Drug Attitude Inventory and safety/ tolerability - Abnormal Involuntary Movement Scale, Barnes Akathisia Rating Scale, Simpson-Angus Scale, and body weight. Data on treatment-emergent adverse events, concomitant psychotropic medications, and medication adherence (pill count and clinician rating scale) were also analyzed for each group. Results: No significant differences were found in any outcome measures between the once-daily and twice-daily dosing groups, which remained the same when using the mean dose of perphenazine as a covariate. Conclusions: Perphenazine is routinely administered in a divided dosage regimen because of its relatively short plasma half-life. However, the present findings challenge such a strategy, suggesting that once-daily represents a viable treatment option. Results are discussed in the context of more recent evidence that challenges the need for high and continuous dopamine D2 receptor blockade to sustain antipsychotic response.
ASJC Scopus subject areas
- Psychiatry and Mental health

domain: psychology


BSP supremo Mayawati said that the move shows the “casteist” mindset of the Modi government.
Ever since BJP came to power on its own, there had been talk of giving Bharat Ratna to the two personalities.
The way in which the government decided to confer this prestigious award to persons loyal to its ideology brings into question the non-partisan spirit of the Bharat Ratna.
The decision came after the announcement of Bharat Ratna for Vajpayee.
The Centre had declared that December 25, the birthday of former prime minister Atal Bihari Vajpayee.
The renaming has not gone down well with the Congress as it slammed the govt for such a ‘regressive’ move.
The other major highlights of the day included new civic schemes and motivational talk.
The former PM won an award for Best Non-Film lyrics in 2000
We recommend that you start your day by reading these five special Express stories.
Vajpayee first met Ghatate in 1957 when he moved to Delhi from Nagpur to study law.
Vajpayee had famously advised Modi to adhere to “rajdharma” in the aftermath of the Godhra riots.
The Bharat Ratna announcement sent news channels on a nostalgia trip
We need to celebrate Vajpayee and Malviya — and the values they stood for.
Ghatate said the former prime minister remains ‘one of the most respected politicians in the country’.
Here’s what the celebrities tweeted following the government’s announcement regarding the Bharat Ratna:
Best of Express


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Meet the Doctors of Westside Internal Medicine Associates
Dr. Nina Priven
Dr. Priven received her undergraduate degree from Emory University and medical degree from The Mount Sinai School of Medicine. She completed her residency at The Mount Sinai Medical Center and joined Mount Sinai Westside Associates in 2000. In 2003 the practice became Westside Internal Medicine Associates, a private practice with a voluntary affiliation with the hospital. The practice has continued to thrive ever since and welcomed the addition of Dr Emily Wang in 2017.
Dr Priven maintains her board certification with the American Board of Internal Medicine.
The practice sees patients 18 years and older.
Dr Priven is in network with the follwing insurance plans:
Blue Cross/Blue Shield for Mount Sinai Employees
*United Health Care
*currently closed to new patients
Dr. Emily Wang
Dr. Wang received her undergraduate degree from New York University and her medical degree from the Albert Einstein College of Medicine. She completed her Internal Medicine residency training at the Mount Sinai Beth Israel Medical Center. After residency she practiced for 6 years as a primary care physician at the Mount Sinai Faculty Practice Associates on the Upper East Side. In early 2017 she joined Dr. Priven at Westside Internal Medicine Associates and also continues as a voluntary physician with Mount Sinai. She is board certified in Internal Medicine, and sees adult patients 18 years and older.
Mount Sinai Empire Blue Cross Blue Shield
United Healthcare Empire Plan
(For the most current insurance information, please contact our office.)

domain: health


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Enjoy an afternoon of Jazz Age beauty, glamour and fashion as we present a roll call of the 1920s debutantes perfectly preserved by the Mary Evans Picture Library.
Until the middle of the last century, London’s social calendar was dominated by ‘the Season’, a round of social events and parties during which the daughters of the upper classes made their ‘debuts’. Debutantes and their families descended on the capital from all over Britain to take part in this elaborate process that in its blend of glamour, archaic and sometimes comic ritual is emblematic of a world now lost. From the preparations and formalities of court presentation to the exhausting round of parties that followed, Luci Gosling provides a detailed look at a phenomenon that was central to the lives of generations of privileged young ladies. Highlights include How to be a Debutante, the workings of the Royal Court and dancing and romancing in the 1920s. Lucinda Gosling is the guest curator of the Museum’s Gordon Conway display and the author of Debutantes and the London Season, published by Shire. She is part of the team at the historical specialist Mary Evans Picture Library, and writes the blog.maryevans.com. Her interests include 20th century social history, royalty, high society and illustration, and she has contributed to a wide variety of publications including History Today, Majesty Magazine, Tatler, Illustration, Stand To!, and BBC News Online.
*Free talk with exhibition entry Event supported by Mary Evans Picture Library


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Authors, Writers, Publishers, and Book Readers
- Just a few things to foster further conversation and discussion...
Here are my thoughts about the overall theme or storyline of my book, The Janus Paradox, and the Twinned Souls book series from which it is born:
The overarching storyline of the Twinned Souls series relates to a bond of love surviving over the course of many millennia, as souls reconnect with each other, time and again, across physical, cultural and emotional distances. Of greatest importance, I believe, is the idea that the bond is vastly interconnected – and there are far more than two souls involved.
The stories connected to the Twinned Souls series will always be about exploring the ability of the human soul to recognize and reconnect with others whom we've bonded with in one way or another through time – past, present or future. (Even while I have a great deal of fun playing with people's concepts of what is the past, present and/or future :)
The secondary or underlying theme is the idea that discovering such a bond of love is a great gift – but learning how to express it to each other, is almost always complicated. Such a bond is rarely anything but a complex interweaving of physical and/or intellectual attraction, combined with the ability to relate and communicate with each other. In addition to sheer proximity, finding that bond sometimes, but not always, depends on a commonality of intelligence, culture, , personal experiences and philosophy, etc. Even cultural taboos will play a significant part. To some degree I dismiss the attraction of straightforward sex, which I frankly consider instinctual, and as most of us know, is not always linked to romantic love, let alone a loving friendship.
Something I genuinely look forward to in writing more books based in the Twinned Souls story-universe is the idea that with each bridging adventure, Glen and Alyse are going to have to overcome major challenges in how they relate to one another – especially when they discover that in their other lifetimes they have not always been romantically connected.
In the next book (Timebound), one of the incarnations that’s explored is one where their souls are brother and sister. It’s also in that book where more is learned about Glen and Alyse’s birth-souls – when they first emerged as human beings on earth – seventeen thousand years ago. The nature of their emergence as sentient beings is at the heart of the fierce bond they share. In that incarnation their biological relationship is best described as half-brothers however, it’s far more complex than that – as they are each born to different women, fathered by the same man – however the women are twin-sisters and as one dies giving birth, her death-experience is shared with her twin and together they unwittingly impart that experience with their sons just as they are being born.
Glen and Alyse will experience being in other sibling relationships, as well as parent and child. I think what might prove to be the most frustrating of all for them, there will be instances where they were “Just friends”…
I’ve already been asked an interesting question by one of my pre-readers:
"..Will they ever be together with one as a lover of the Úlfgeirr spirit (like the path Ælfwyn almost chooses with Úlfgeirr in Janus Paradox) where [the Glen soul] must be the third? You are going to have fun with your readers, non?..."
Answer: Oh yes indeed… I plan to have a great deal of fun with both my characters and my readers!
Thank you all for your interest and encouragement on behalf of Twinned Souls - Book One: The Janus Paradox


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How to Have a Thinner Thanksgiving
Does thinking of Thanksgiving dinner make your jeans feel a little tighter? It should. The average Thanksgiving dinner can pack a huge calorie punch, often weighing in at 3,000 calories and 200 grams of fat. But, don’t blame the bird. A traditional thanksgiving feast is full of nutritious foods that we tend to make as calorically dense as possible — we are notorious for pumping the sides full of butter, oil, cream, and sugar.
Luckily, you don’t have to give up everything you love about Thanksgiving dinner to stay on track with your diet. To avoid over-indulgence that can be hard on the waistline, a few easy substitutions can make all the difference.
And remember, portions are key. This is what may take you from a 1,000 calorie meal to a 3,000 calorie overload. Here is step-by-step guide to dishing up your plate with as minimal damage as possible:
- Use the smallest plate you can find (think dessert plate).
- Load half your plate with veggies (preferably ones not slathered in fat and sugar). Great choices are steamed carrots, turnips, and Brussels sprouts. Stay full by selecting about 5 ounces turkey (about the size of the palm of your hand). This will likely cover about 1/4 of your plate.
- Finally, select those items you have been waiting for. Is it stuffing? Or maybe sweet potato? Enjoy about 1/2 cup of either (or 1/4 cup of both).
- Drizzle on your sauces. Yes, it is OK to use about 2 tablespoons of sauces max. Most folks can easily opt for 1 tablespoon gravy and 1 tablespoon cranberry sauce. This is not much however, it is just enough to give you the flavor you are longing for without masking the flavors of the food items it is topping.
- Finish off this great dinner with a very small slice of pumpkin pie topped with 1/4 cup low-calorie whipped topping.
One plateful is plenty. The leftovers tomorrow will taste even better and be worth the wait! Enjoy the holiday weekend and then get back to your regular eating routine ASAP in order to avoid the unwanted holiday weight gain.
Andrea Mawson, BSc, RD, IOC Diploma Sport Nutrition is a nutritionist and private practice registered dietitian specializing in weight loss. She has created an innovative nutritional program that she has used on clients all across Canada to achieve and maintain their best weight, improved health and well-being. For more information log onto www.andreamawson.ca


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BP Plc ( BP ) has inked an agreement with Cameron International Corporation ( CAM ) to settle all mutual claims related to the Deepwater Horizon accident and spill. Cameron, the designer and manufacturer of the blowout preventer (BOP) used on the Deepwater Horizon, has agreed to pay BP $250 million.
The amount - to be paid by January 13 next year - will directly be placed in a $20 billion trust, which BP had formed for payments of claims related to the oil spill as well as damages to natural resources. In the meantime, BP agreed to indemnify Cameron for compensatory claims arising from the spill, including claims relating to pollution stemming from the accident or any damage to natural resources.
BP and Cameron have also decided to withdraw claims against each other in the Multi-District Litigation pending in New Orleans. However, BP's indemnity rules out civil, criminal or administrative fines and penalties, claims for punitive damages, and certain other claims.
BP considers the settlement to be in the best interest of both companies. The British oil major also added that the agreement is not an admission of liability by either party.
A new report into the causes of the spill found the design and maintenance of the BOP on the Deepwater Horizon unsuitable. The report held that the BOP was not properly designed or tested for the conditions that existed at the time efforts were made to recapture well control.
BP has already reached settlements with its partners in the Macondo well, Mitsui and Anadarko Petroleum Corporation ( APC ), as well as Weatherford International Ltd. ( WFT ), the manufacturer of the float collar used at the well.
Earlier this week, Transocean Ltd. ( RIG ), owner of the giant Deepwater Horizon platform which was leased by BP, held that it is not liable to pay any federal fines or penalties for oil spilled below the surface in the Gulf of Mexico because of an indemnity provision in its drilling contract with BP.
Countering Transocean's conduct, BP stated that the agreement does not cover liabilities that result from willful misconduct. Transocean on the other hand, is denying any willful misconduct during the drilling of the Macondo well.
BP holds a Zacks #3 Rank, which is equivalent to a Hold rating for a period of one to three months. For the long term, we maintain a Neutral rating on the stock.
The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.


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I think my mojo's been hibernating. Ever since I finished the blue dress and handed it over, I haven't really felt like sewing. Oh, I've felt like it, all right, but not to the point where I actually accomplish anything.
I go in the room, I look around, I see the UFOs and the mess, and I get disheartened and go and either read or watch TV with the man. Both of which are worthwhile activities - I just finished the new Barbara Kingsolver while being unable to sew - but they weren't really want I wanted to do.
So last night, enough was enough. I was going to sew something, and if that meant I had to tidy up, then so be it. I got rid of the last of the blue scraps, and then I made envelopes for all the patterns I've traced in the last 3 months, and then I put all the patterns and magazines away. And then I faced the UFOs.
The sausage dress. The unfinished black dress. The other one.
The sausage dress had pins in it from where I altered it to fit my friend when it was too small for me. I decide to start with this one. I threw it out. Much as I loved the print, the fabric wasn't that good, and I had deluded myself from the beginning that it was nice enough to work with.
The black dress has been given permission to wait. I'm having a sleeve dilemma, as in which ones to choose. It will come, and then I will finish it.
The third dress is in limbo. There's something way too 80s about it right now, but I still like the general style and the fit and I love the fabric. Since it was drafted from a top I really like, maybe the problem is that it was never meant to be a dress. Right now I'm contemplating taking scissors to it.
Question for all you readers out there: anyone have a good reference for working with fur? I've got my great-aunt's mink sitting downstairs in a bag - I know, only the best treatment in my house. It's got some damage, but I don't want to pay to get it fixed - it's 60 some years old, so it's fragile, and I don't have the cash for a furrier. I'm either going to repair it myself or turn it into something else, but it turns out there's not a lot of information out there on working with fur.
I asked on Patternreview and did get one book reference, but besides a suggestion that I sell the coat because fur isn't in, and I would get a lot of grief for wearing it, and do I know how they harvest the skins . . . not much actual info. Yes, I know I'd get grief. Yes, actually I do know how they harvest the skins, since I have relatives in upstate NY that make a living by selling bait and trapping animals and selling skins. My cousins tried their best to gross me out one summer by teaching me how to skin a squirrel.
But this has come into my possession (and those little minks died) through no act or omission of ine. And the fact that my aunt (and her aunt before her) kept it since the 1940s means I should hold onto it at least a little longer, perhaps until I can't justify wearing it. Who knows? But any info would be greatly appreciated. Lectures, not so much. :)
Oh, and once I cleaned up and dealt with the UFOs, suddenly the fog cleared, I taped and cut out Burdastyle's Heidi pattern, and then I cut out a dress. Feeling much better.
Here is a post from the sewing divas blog about recrafting a mink coat.
How about using the cuffs and collar and making them into detachable collar and cuff set for a plainer wool coat?
Looks like they would be perfect for the weather where you are at the moment!!
I have had some of those same feelings about sewing off and on lately. It sounds like you put it aside and started doing sewing related activities.
Keep the mink, it is truly priceless. Hopefully you can find some more info to be able to get some use out of it.
I don't have any info on working with fur, but I think it's a great idea to reuse it for something you'll love to wear (assuming it's just too damaged or hopelessly out-of-style to use as-is). I like the detachable collar and cuff idea, which you could then use again in the future on a new coat. And a hat? Very Dr. Zhivago.
Tell anyone who says such things to mind their own business. Sorry, but that coat is an antique, the minks long dead, you didn't BUY it (supporting the industry), it was a gift through inheritance, etc. If it's wearable, wear it when you dress up. The whole PETA thing about furs drives me crazy, why shouldn't you enjoy it, given the reasons listed above. I think another blogger in NYC (Sewing in the City) wears her vintage fur coat. Or recraft it, if you wish, but put it to use in the way you see fit. Got the slip, it's beautiful as is the little hankie enclosed. Thanks, Myra
I've done some repair work and alterations on fur for customers before and would be happy to give you suggestions, but it'll kind of depend on what kind of damage you have. Feel free to email me at cisabarry at gmail dot com and I'll see what I can come up with! I've got a pretty fabulous/ridiculous fur coat laying around that someday I'll finish mending for myself.
Wow! It looks cold there. I get cold just looking at them - think that I'll save this post for August here in Florida. Glad to hear that your sewing mojo is returning. I enjoy seeing what comes out of your sewing area. Congrats on clearing up your sewing space - I'm going to get to that soon!
Great job motivating yourself. It's hard to get out of the sewing funk, but you did it!
Good luck with the fur sewing - I haven't tried it yet, myself.
I've heard of people having vintage fur coats made into teddy bears, but I don't think you'd have much use for a teddy bear. I inherited a coat with a fur collar from my grandmother. Love the coat, can't bring myself to wear it. Maybe you will inspire me.
Leave the guilt and the fear of judgment behind. Those little minks have been long gone for over 70 years, and there's no reason it should be in vain. Refashion the coat that you inherited, and keep it in the family. And good for you getting some projects going. I have been in the same boat-- I walk in, look at the mess, and decide... maybe later. When what I really want to do is sew!
Seriously, I'm so un-pc about fur! I really don't care that Oprah doesn't wear it anymore...it's warm and in the weather we are having now...it's perfect to wear!
So I hope you come up with a wonderful refashion for your aunt's coat!
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"It would be a mistake to assume that COVID-19 has created these gaps in educational access. All it’s done is bring them to light."
QUIZ: Dress Pop Culture Icon Carly Rae Jepsen and I’ll Tell You What Carly Rae Jepsen Song to Listen To
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On the upcoming GUSA election ballot, students will vote on three referendums, two of which pertain to sustainability. Though the referendums will not bind the university to action, they present... Read more
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Endometrial Carcinoma: Pathology and Genetics
Moderator: Dr. Michael A. Wells
Section 5 -
Molecular Alterations in Non-Endometrioid Carcinomas of the Endometrium
C. Blake Gilks
Vancouver General Hospital and University of British Columbia
Vancouver BC, Canada
The Simple Version
There are two distinct pathways of endometrial carcinogenesis, leading to clinically and
pathologically distinct subtypes of endometrial carcinoma. The first pathway (Type-1 cancers) is
associated with hyperestrogenic states, leading to the development of atypical endometrial hyperplasia,
which progresses to endometrioid carcinoma. The second pathway occurs independent of the growth
promoting effects of estrogen, with the earliest recognisable pathological alteration being endometrial
intra-epithelial carcinoma, which progresses to uterine serous carcinoma. The following table highlights
the important differences between type-1 and type-2 cancers.
TABLE 1. Endometrioid (Type-1) versus Non-Endometrioid (Type-2) Endometrial Carcinomas
The More Complex Version
| ||Endometrioid ||Non-Endometrioid|
|Hyperestrinism/ER expression ||+ ||-|
|Complex atypical hyperplasia ||+ ||-|
|p53 mutation/loss ||- ||+|
|PTEN mutation/loss ||+ ||-|
|Microsatellite instability ||+/- ||-|
While the epidemiological data supports there being two distinct pathways of endometrial
carcinogenesis, the situation in clinical practice is more complex, and much more interesting.
Hendrickson et al. observed that the designations of type-1 and type-2 carcinoma describe "two loose
clinicopathologic clusters or syndromes"  rather than reproducibly recognizable groups. The
designations of type-1 and type-2, indicating tumours arising as a result of estrogenic stimulation, and
independent of estrogen, respectively, have never come into routine use diagnostically; although they can
be readily applied to many cases of endometrial carcinoma, a significant number of cases defy
classification as either type-1 or type-2 carcinoma. Examples of such cases include uterine serous
carcinoma associated with complex atypical hyperplasia, or mixed endometrioid and serous carcinoma.
Therefore, these designations are useful in a general sense in understanding endometrial carcinogenesis
but are an oversimplification and not clinically relevant for anatomical pathologists in routine
day-to-day practice. In contrast, designation of the histological subtype of an endometrial carcinoma is
routinely done in clinical practice and this cell-type assignment is used to guide patient therapy.
Accordingly, in this presentation the focus will be on molecular abnormalities in the clinically
important group of non-endometrioid carcinomas, rather than a discussion of general pathways of
endometrial carcinogenesis. Before discussing these molecular abnormalities we will first review
background information of relevance to surgical pathologists.
The reproducibility of histopathological assessment of endometrioid vs non-endometrioid cell type.
Meaningful studies on molecular abnormalities in subtypes of
endometrial carcinoma can only be done if we, as diagnostic pathologists, can accurately diagnose those
subtypes. Unless we can reproducibly recognise uterine serous and clear cell carcinoma, there cannot be
progress in understanding the molecular events of importance during oncogenesis, or rational introduction
of new treatments. We recently examined interobserver reproducibility in assignment of cell-type of
endometrial carcinomas, based on three reviewers examining a single representative slide from fifty
consecutive cases . There was substantial but not perfect interobserver reproducibility in assignment
of cell-type (kappa = 0.70). This would undoubtedly be lower if only high-grade tumours were considered,
as in common, low-grade endometrial adenocarcinomas of endometrioid-type distinction from uterine serous
carcinoma is not an issue. It is only within the smaller subset of higher grade tumours where this
becomes problematic and although this group of tumours has not been examined specifically, it is likely
that the reproducibility in assignment of cell-type in high grade endometrial cancer is suboptimal As
patient management may vary depending on whether we diagnose uterine serous carcinoma or not, efforts to
improve reproducibility are desperately needed. In the meantime, for research purposes it is possible to
focus on very typical, pure examples of uterine serous or clear cell carcinoma for molecular studies, to
minimise the effect of inter-observer variation in diagnosis, but it is important to remember that these
cases may not be representative of all cases of uterine serous or clear cell carcinoma encountered in
practice, especially mixed tumours.
Association of non-endometrioid carcinomas with inherited cancer susceptibility syndromes (HNPCC, BRCA).
Our insight into the molecular events underlying a number of different
carcinomas has been greatly advanced by understanding the genetic basis of inherited susceptibility to
these cancers. For non-endometrioid carcinomas of endometrium there are two relevant cancer
susceptibility syndromes. Familial breast and ovarian cancer, associated with mutations in BRCA1 and
BRCA2, is associated with little or no increase in the likelihood of developing endometrial carcinoma of
either endometrioid or non-endometrioid type. Case reports have documented patients with germ-line
mutations in BRCA genes who have developed uterine serous carcinoma, but, unlike serous carcinoma or
ovary, tube or peritoneum, uterine or cervical serous carcinomas are not a major contributor to cancer
risk in these patients. Although this is perhaps counterintuitive, given the morphological similarities
of serous carcinoma of ovary/peritoneum/fallopian tube vs serous carcinoma of endometrium, there are
other molecular differences (e.g. frequent expression of WT-1 in the former but not the latter, more
frequent Her-2 amplification in the latter than the former) suggesting that there are fundamental
differences between these serous tumours arising at different anatomic sites.
Endometrial carcinoma is a very significant part of the spectrum of disease associated with Hereditary
Non-Polyposis Colon Cancer (HNPCC) syndrome, being the second most common malignancy after colonic
adenocarcinoma. Endometrial carcinomas associated with HNPCC are more frequently higher grade, and
present with higher advanced stage disease, compared to sporadic cases of endometrial cancer. In a
recent study by Carcangiu et al., endometrial carcinomas arising in HNPCC patients were often of
non-endometrioid type (46.3 % of vs. 53.6 % of endometrioid type) . Many of these non-endometrioid
carcinomas were mixed (e.g. 6 of 11 clear cell carcinomas were mixed clear cell and endometrioid
tumours). This indicates that that mismatch repair defects can contribute to development of some
non-endometrioid carcinomas (more about this later).
Specific genetic abnormalities in non-endometrioid carcinomas
- P53: Mutations in P53 are found in most non-endometrioid
carcinomas, and are the most characteristic genetic abnormality in this set of tumours; the precise
percentage of cases with loss of P53 is impossible to state due to differences in case selection and
methods of testing for P53 mutations. For surgical pathologists, p53 immunostaining is an inexpensive
surrogate for P53 mutational testing; p53 immunoreactivity (defined as strong diffuse nuclear
immunoreactivity) is seen in most cases of non-endometrioid carcinoma . It has been suggested that
p53 immunoreactivity can be used diagnostically to support a diagnosis of uterine serous carcinoma but
this requires correlation with morphology as endometrioid carcinomas also can have mutations of p53, and
not all non-endometrioid carcinomas exhibit p53 immunoreactivity. Loss of p53 function leads to genetic
instability, with the result that there is widespread loss of heterozygosity/allelic imbalance in
non-endometrioid carcinomas with mutant p53, and frequent aneuploidy.
- PTEN, microsatellite instability (MSI), k-RAS: Mutations in PTEN
and k-RAS, while common in endometrioid carcinoma, are rarely encountered in non-endometrioid carcinomas.
MSI is more common in endometrioid carcinomas but is also present in occasional cases of non-endometrioid
carcinomas (11% in the study of Catasus et al. ) and, as noted previously, non-endometrioid
carcinomas are encountered with increased frequency in patients with HNPCC.
- Her-2 amplification: Her-2 amplification was identified in 47% of
cases of uterine serous carcinoma by Santin et al. , and Her-2 amplification was associated with a
significantly worse outcome, compared to those patients whose tumours did not show amplification. This
observation is of great potential impact. It may be that gene amplification events are critical in the
genesis of uterine serous carcinoma, an important discovery given how little we know about genetic events
important in the development of these tumours. Interestingly, Slomovitz et al. did not find this high
frequency of Her-2 amplification in their series of cases , however they included mixed tumours, while
the study of Santin et al. included only pure examples of uterine serous carcinoma. It remains to be
seen whether Herceptin therapy will be effective against uterine serous carcinomas with Her-2
amplification; the amplification ratios were relatively low in most cases, and heterogeneity of Her-2
amplification was seen in 4/14 cases.
Use of Panels of Immunomarkers in Classification of Endometrial Carcinoma
TABLE 2. Immunomarkers in Endometrial Carcinoma
|Marker ||% expression ||p-value|
|Total ||Grade 1&2 endometrioid ||Grade 3 endometrioid ||USC & Clear cell|
|p53 ||16% (25/155) ||2.8% (3/107) ||38% (13/34) ||64% (9/14) ||<0.0001|
|ER ||89% (139/156) ||97% (106/109) ||79% (27/34) ||46% (6/13) ||<0.0001|
|Her2Neu ||4.5% (7/155) ||0% (0/107) ||3% (1/34) ||43% (6/14) ||<0.0001|
|E2F-1 ||24% (37/153) ||18% (19/106) ||32% (11/34) ||54% (7/13) ||0.008|
Table 2 shows the immunophenotype of different subsets of endometrial adenocarcinoma stained at our
centre. It is clear that no single immunomarker can serve as a discriminator between endometrioid and
non-endometrioid carcinomas. An obvious next step is to use panels of immunomarkers that each,
individually, show differences in staining between endometrioid and non-endometrioid carcinomas. When
such data is generated, either supervised or unsupervised analytical approaches can be applied to the
data. With supervised approaches the cases are assigned to categories (e.g. endometrioid vs
non-endometrioid) based on morphological examination. This approach assumes that our morphological
assessment is accurate. In unsupervised analysis, no assumptions are made based on the clinical or
pathological features of the cases, and the immunostaining results are considered completely
independently. Darvishan et al. used a supervised approach to data analysis to demonstrate that the
combination of p53, PR and PTEN were the most useful in distinguishing between uterine serous carcinoma
and endometrioid carcinoma . Using unsupervised hierarchical clustering analysis, and a panel of 9
immunomarkers, we were able to demonstrate that three subsets of endometrial cancer are identifiable .
There is a large group composed of predominantly low grade endometrioid adenocarcinomas that are
characterized by ER +ve, p53 –ve immunophenotype. These are classic type-1 tumors. Another smaller
group of tumours, consisting predominantly of uterine serous carcinoma, shows an ER -ve, p53 +ve
immunophenotype. These are classic type-2 tumors. The third group is characterised by positivity for ER
but also positivity for p53 and/or other oncogenes not typically seen in low-grade endometrioid
carcinoma. It is likely that these tumours start off as lower grade, hormonally sensitive tumours, and
through accumulation of new mutations become higher grade. I suspect that these cases are
under-represented in many of the studies of molecular events during endometrial carcinogenesis, as more
"typical" examples of pure endometrioid or non-endometrioid carcinoma are selected for study. This third
group would account for the finding of atypical hyperplasia in association with non-endometrioid
carcinoma, the mixed endometrioid/non-endometrioid carcinomas in general, and more specifically those
arising in patients with HNPCC syndrome, and the differences in frequency of Her-2 amplification in
studies with different case characteristics
It also suggests that the definition of mixed
adenocarcinoma of the endometrium as "a tumour composed of an admixture of a type-1……and a type-2
carcinoma"  should be revised, as mixed tumors are more likely to be type-1 tumors with progression
to higher grade malignancy.
- Hendrickson MR, Longacre TA, Kempson RL. The uterine corpus. Sternberg's Diagnostic Surgical Pathology 2004:2460-84.
- Alkushi A, Abdul-Rahman ZH, Lim P, et al. Am J Surg Pathol, 2005;29:295-304 .
- Carcangiu ML, Dorji T, Radice P, et al. Mod Pathol 2006;19S1:173A.
- Alkushi A, Lim P, Coldman A, et al. Int J Gynecol Pathol 2004;23: 129-137.
- Catasus L, Machin P, Matias-Guiu X, Prat J. Human Pathol 1998;29:1160-64.
- Santin AD, Bellone S, Van Stedum S, et al. Cancer 2005;104:1391-7.
- Slomovitz RM, Broaddus RR, Burke TW, et al. J Clin Oncol 2004;22:3126-32.
- Darvishan F, Hummer AJ, Thaler HT, et al. Am J Surg Pathol 2004;28:1568-78.
- Alkushi A, Lim P, Coldman A, et al. manuscript submitted.
- Silverberg SG, Kurman RJ, Nogales F, et al. Epithelial tumours and related lesions. World Health Organization Classification of Tumours: IARC Press, 2003:221-32.


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-Which form of Business to Start, benefits, disadvantages, Government compliances required?? –TaxGoal
Key: Company Registration in Delhi, Company Registration
To start a new business in India, it requires a great zeal of planning for
- The requisite finance required;
- The workflow in the organization;
- The number of employees to acquire;
- The legal policies to comply with;
- The tax provisions and a lot more.
Taxgoal is a reputed CA expert service provider in Delhi, which guides you through out your business incorporation process till it becomes an entity to start its business legally. Our dedicated team of experts provide you online company registration services in Delhi and takes in the complete process of your business registration, saving you from complications and delays experienced in the filing process.
As the tax filing season slips in, every taxpayer shell out to look for all possible ways to reduce his tax levy. Out of the minimum tax slab exemption, the short deviations provided by the government in the form of deductions under multiple tax sections also work in reducing the taxable income to a great extent.
Striving to make a last push to its targeted vote bank, the NDA government presented its Final Union budget for 2019-20 in the Lok Sabha Session held on 1st February 2019. Led by the Interim Finance Minister Piyush Goyal, Budget 2019 considered all in round expectations of all sectors from Agriculture to tax to defense to Infrastructure and provided major reliefs & benefits to the middle class and the unorganized sector
What is Reverse Charge Mechanism? Mr. A is a small trader of goods in Delhi having turnover below 20 Lakhs and purchases goods from a supplier who is not registered under GST, does he require to take GST registration under Reverse Charge Mechanism (RCM) in Delhi?
31st July 2018 is the due date for filing of Income Tax Return for Individuals, Hindu Undivided Family (HUF), Association of Persons (AOP), Body of Individuals (BOI) and Non Audit Assessees.


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- Jan 10, 2011
- South Carolina & Maine
I have a few NFA SBRs and this Getz MP5 clone is one of them. It's fun to shoot but installing any kind of optic (red dot) isn't easy. A picatinny rail would be nice. I've shot MP5 and the UZI guns in full auto configuration and the best of the two is the UZI. Its weight and somewhat slower fire rate makes it easy to stay on target.

domain: hobby


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Every year I do St. Patrick's Day cards for my family and friends. It's a big holiday in my family and so I try to do something special. I usually spend lots of time watercoloring and all but this year I decided to do something totally not me. I used the Cuttlebug hearts to make my shamrocks. I used green designer paper for the larger shamrock and then SU Garden Green for the smaller Shamrock The stem was made by cutting a piece from the left over heart frame. I added the paper piercing in the corner because it just needed something. Hope my family and you enjoy this! Thanks for looking!
Date: Friday, March 16, 2007 GMT Views: 475

domain: design


RGV with Manchu Vishnu?
By Sanjay Tiwari on November, 18 2013
If reports are to be believed, then maverick film director Ram Gopal Varma and young hero Vishnu Manchu is expected to team up very soon.
Sources say that the film is expected to be a comedy entertainer and initial discussions reportedly took place between Vishnu and RGV.
Sources also say that...
READ MORE »


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Day 9 – A Movie You Practically Know the Whole Script To
The Last Five Years
So for this one, I was going to talk about a musical or animation, and since I did an animation yesterday, I chose a musical for today. I talked about this movie in Angela’s Favourite Musicals. It’s originally done on stage (Which I’ve never seen), but I love the movie version. I know the whole album (and therefore the movie) pretty much off-by heart.
Basically, the film follows Cathy and Jamie and their love story over the span of five years. From meeting, to falling in love, to getting married, to their break up. What I love about this film is that it’s kind of in reverse order. The film opens with Cathy at the end of the relationship, heartbroken. Then it jumps to Jamie’s point of view when they first meet and they’re head over heels. The film continues in this way. It goes backwards with Cathy, but goes forward for Jamie, where they meet in the middle for a duet when they get married. It sounds confusing, but it works so well.
My favourite is definitely the last song (the only other duet), where Cathy has just met Jamie and is completely happy in love “Goodbye Until Tomorrow”, but Jamie is singing goodbye at the end of a 5 year relationship with her “I Could Never Rescue You”.
Have you guys heard of or seen this film?
What’s a movie that you know practically the whole script of?


text: I used this once and I just put it on my chin and cheeks. It felt fine at first but when I woke up, I had either contact burns or a rash where the product was applied. It didn't bother me at first, it was just really red, then it started to burn and itch. I'm still in the process of healing it. Safe to say I won't be using this again.


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The sky’s mood used to be caught in the water of the lake. When the clouds subsided, the lake was also black. The blue water of the Lake filled with Autumn used to splash in the ghat. To maintain the natural balance of the city of Kolkata, houses and shops have been built one by one after the lake dug by Maharaja Yogendra Narayan of Jiaganj, Murshidabad. It blocked the way out of monsoon water, drainage problems have also started. Residents claim that there was no result despite informing the administrator. Recently, a written complaint was given to the Lalgola BLRO office by the ‘Watershed Protection Committee’ of Murshidabad district regarding the filling of the pond at a stone throw distance from the Lalgola police station in the heart of the city.
Almost everywhere in the state of West Bengal there are such complaints about cutting of soil. It is alleged that soil smuggling has been going on freely for years in the areas like Shashan, Kharibari, Phalti, Rajarhat of North 24 Parganas. According to local sources, many people have been killed in the area over the past few years, many of whom were directly or indirectly involved in the soil business. Due to the unplanned cutting of soil, the villages around the tributary river of Vidyadhari overflowed the bank of Vidyadhari in the last monsoon.
Barasat district police claim that after many attempts, control over soil smuggling has been brought. Local MLA Haji Nurul Islam said, “The police have been asked to be active so that the previous situation does not return. If there is anything illegal, we will inform the police as soon as we get the information. Illegal cutting of soil will not be tolerated in any way.” According to a senior district police official, “Currently only government-designated agencies are getting permission to cut soil.”
But once permission is obtained, there is an example in Malda of how the soil mafia uses it. In Lakshmipur Gram Panchayat area of Kaliachak Third block, the land revenue department allows cutting of soil in the Ganga for one to two months, but it is found that at least four to five times more than the amount of soil supposed to be cut has been cut and smuggled. Last year in Lakshmipur, the land reform department and the police conducted a joint operation and fined around 5.5 lakh rupees. Even after that till the water of Ganges rises, the soil is cut.
What is done with that soil? In different areas of the district including Engrezbazar city, the soil taken from the river is also used for filling the wetlands. Houses are being constructed by draining swamps in Chatra Beel area of the city. It is alleged that the character of the land has also been changed in the papers. Malda Additional District Commissioner (Land Revenue) Shampa Hazra, however, said, “Action is taken when there are complaints of illegal cutting of land.”


£346.50– Sold Out
The Smith Bag has a detachable and adjustable strap which means it can be used as a Top Handle Bag (with secure fasteners on the sides) as well as a shoulder bag or a crossbody bag. Big enough for a book, kindle or even an iPad and great for the work commute or just around town; With plenty of space, compartments and features to organise the everyday essentials. Available in a wide range of colour options including both bright and neutral tones. Seen here in a vibrant pillar box red which is sure to grab the attention it deserves
Our handbags are made using leather both inside and out. We use the best Italian nappa leather on the outside and the handbags are lined with an eco-friendly natural pigskin leather on the inside (which means no harmful chemicals or dyes are used). This helps to make our bags incredibly soft and luxurious but also durable and longlasting.
Our signature feature that we have become known for is genuine Springbok hair-on-hide leather. The ethical source of the materials is very important to us. Springbok (Antidorcus Marsupialis) are not cites classified which means there is no threat to the survival of the species. The animals live freely in abundance in South Africa. The sustainability of the species is carefully managed and the population is culled to keep the ecosystem in balance. Not only does this protect the species, but it also protects the habitats in which they live and helps to support the liveliloods of the local communities. The local food industry benefits and the by-products are also utilised in decorative ways in interiors, furniture and fashion.
All our leathers are a by-product of the food-industry.
We use only high quality YKK zips and silver-coloured metal chains, studs and handbag hardware.
All our handbags are offered with a white cotton dustbag to keep them clean.Read more about the Sustainability Journey of Sherene Melinda


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When Metro Exodus first released in 2019, it managed to straddle the line between console generations. Its console versions dialed back the visuals to maintain a stable framerate while the PC version was one of the very first titles to offer support for hardware-accelerated ray tracing features via Microsoft’s DXR. The PC version looked leagues better than the console version, but when pushed to the limit, it was still capable of bringing the best PCs to their knees.
Fast forward a little over two years and 4A is releasing Metro Exodus Enhanced Edition. In a release that seems like it would be made explicitly for the PS5 or Xbox Series X, the reality is that PC gamers get a bit of an exclusive this time around. The development team has implemented the latest updates and features granted by the most recent GPU releases and has built a new version of the game that looks and runs better than ever before.
Dirt, dust, and grime never looked this good before
I’ll lightly touch on the game design and experience of playing Metro Exodus because I know that it may have gone overlooked by some the first time around, but prospective buyers should know that the overwhelming majority of the enhancements delivered by this new edition are for the technical/visual side of things. The game itself remains intact, for better or worse.
I would be inclined to recommend it to any FPS fans or those who may be growing weary of the ocean of AAA games that mandate online interactivity and cosmetic sales. As odd as it may seem, the marketplace is mostly bereft of true single-player shooters with this kind of production value. It is a genre that used to be bursting at the seams with releases more than a decade ago, but the financial realities of video game production often mean that most games end up being designed to be all things to all potential audiences.
Metro Exodus aims to tell its story through a linear campaign that holds many of the same tropes invented by Half-Life some twenty-plus years ago. It doesn’t really break new ground with mechanics or storytelling, but it knows what it is and I personally find it appealing. Though 4A Games now resides in Malta, the studio’s Ukrainian roots manage to shine through at nearly all times. The Metro games ooze with an uneasy vibe and a bit of jank that you won’t find outside of Eastern European or Russian-produced games. They have a soul, but it certainly is not for everyone.
Moving onto what is new with Metro Exodus Enhanced Edition, players can expect a total reworking of how the game handles lighting, shadows, and reflections. Those without DXR-capable GPUs need not apply as the game client requires such hardware to run. For the first time that I know of, we now have a game with AAA production values that is using fully ray-traced illumination. I wrote a feature last week that dives into the finer details and explains the differences between how the original release and the Enhanced Edition render their scenes.
What does this all mean when it comes to playing? Things look much more realistic, even to the point of being unnoticeable if you aren’t looking for them. Light bounces off of surface materials and can cast objects in various hues that were simply not possible with rasterized rendering. Certain sections of the game that were so dark you couldn't make out details are now much closer to how they would look in reality or a movie. As a general rule, I found everything to be a few notches brighter than the original release while playing in SDR. In HDR mode, the boosted contrast offers striking highlights without crushing details in the darkest corners. This is a glimpse at where video game rendering is headed and it can be experienced now.
All things being equal, Metro Exodus Enhanced Edition looks better than its PC predecessor and offers measurably higher, more stable performance. The addition of support for NVIDIA’s DLSS 2.1 upscaling feature takes things even further. The amount of ray tracing calculations required to deliver the Enhanced Edition’s visuals on the Ultra preset are incredibly large, but DLSS allows you to experience it at 60fps on current hardware. Using a Core i9-9900K and RTX 3080, I was able to play at 3840x2160 resolution with all the bells and whistles at a stable 60fps when using the DLSS Performance option. While this renders the game at a native 1920x1080, the resulting output is so close to native 4K that it doesn’t matter that you aren’t playing at “real” 4K.
Down to your last filter
Metro Exodus Enhanced Edition will be a free upgrade for anyone who previously owned the original game on Steam, Epic Games Store, GOG, or Windows 10 Store. It will be a separate library entry due to the massive changes in how the game renders. If you missed it the first time around or have been on the fence since 2019 (your butt must be impossibly numb at this point), I can wholeheartedly give this new edition the thumbs up. Here’s hoping you can actually find a compatible video card for sale — a feat that may be more difficult than surviving in Metro’s irradiated wasteland.
These impressions are based on the PC Steam release. The game key was provided by the publisher for coverage consideration. Metro Exodus Enhanced Edition is available now for PC. PS5 and Xbox Series X versions are scheduled for release later this year.
Chris Jarrard posted a new article, Metro Enhanced Edition impressions: I like this Ray Trace guy
Really looking forward to trying this today! Gorgeous screenshots.


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Model : Shara R.
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University of Redlands Emergency Alert System
Alert Received: . For more information, visit: https://redlandsalert.com/
The Pride Center coordinates the Transgender Day of Remembrance to raise awareness of and honor the pain suffered by this community because of discrimination and violence. We host a vigil and informational displays to educate the campus community about this day.
CDI will observe Transgender Day of Awareness on Monday, November 21.


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Officials in Beijing summoned the Japanese ambassador Thursday after members of Japan’s Cabinet took part in a controversial annual ceremony memorializing Japan’s war dead.
China issued a strong complaint from its Foreign Ministry and summoned Japan’s ambassador Thursday after two Japanese politicians visited a Tokyo shrine to commemorate Japan’s war dead. China’s Foreign Ministry said the shrine visit “seriously” harms the feelings of the Chinese people and other Asian countries.
In addition to the two Cabinet ministers, about 90 Japanese lawmakers visited the shrine. Japanese Prime Minister Shinzo Abe elected not to visit Thursday, but sent an offering through an aid.
“I asked my special aide to make the offering on my behalf with a feeling of gratitude and respect for those who fought and gave their precious lives for their country," he said.
Abe instead participated in a government-sponsored secular ceremony, where he said he hoped Japan reflected on history and did not repeat the misery of war. However, unlike his predecessors, he did not express remorse over Japan’s wartime aggression.
The Yasukuni shrine is dedicated to Japan’s 2.5 million war dead, including convicted war criminals. Japan’s neighbors say the Shinto shrine is a symbol of atrocities committed by Tokyo during World War II, and annual visits by Japanese officials are routinely condemned in China, Korea and Taiwan.
China’s Global Times newspaper stated that in recent years “Tokyo has slipped further to the right under the hawkish Abe administration.” Other media noted recent surveys indicating that more than 90 percent of Japanese and Chinese have an unfavorable view of each other.
Xiaohe Cheng is a Professor of International Relations at Renmin University. He said many in China expected Japan to change its pacifist constitution and rise again as a military power.
“The normal statehood from a Chinese perspective carries very important meanings that Japan will revise its peace constitution [sic] and will expand its military and military forces and also try to gain weapons, including aircraft carriers and possibly nuclear weapons,” he said.
Thursday’s shrine visit also angered South Korea, where President Park Geun-Hye indicated many Koreans believe Tokyo has not fully apologized or accounted for its wartime behavior.
She said Japan was an important neighbor for peace and prosperity in Northeast Asia. However, the current situation surrounding the issue of past history darkens the future. President Park said it was difficult to build trust towards the future if one did not have courage to look squarely on the past and attitude to consider pain of the opposite party.
As part of Korea’s own ceremonies marking its anniversary of liberation from Japanese colonial rule, authorities held a traditional Korean martial arts competition on an island claimed by both Japan and South Korea.

domain: politics


Ukraine successfully tested long-range Lantset-style loitering munitions domestically, the digital minister announced, with serial production possible within months.
Minister: Ukraine has “over five” mass-produced analogs of Russia’s Iranian-made Shahed explosive drones
"We have more than five mass-produced analogs of Shahed-131 [long-range suicide drone]. And there is one type that is analogous to Shahed-136," Ukrainian minister says, adding that those are mass-produced.
Ukraine is rapidly boosting drone production to fulfill military requirements, with a focus on efficiency and diversification of drone models, as per Defense Minister Rustem Umerov.
Ukrainian forces operate hundreds of Vector drones, which get improvements based on the combat use experience.
Russian forces again used occupied Crimea to launch overnight drone attack across Ukraine, employing 19 drones targeting multiple regions; Ukraine's air defenders downed 18 of the UAVs, as per Ukraine's Air Force.
Ukraine responds to artillery shell shortages by intensifying kamikaze drone production, focusing on defense industry collaboration with Western companies, as per Deputy Defense Minister.
Ukrainian engineers have developed and launched the Cobra fixed-wing "kamikaze" drone manufacturing, with a 300 km operational range and 15 kg payload capacity, using riveted steel construction for rapid and affordable production.
Ukraine's military receives its first AQ 400 Scythe drones with a remarkable 750 km range; the manufacturer says it produces 100 Scythes monthly and targets 500 units a month, emphasizing local production.
Ukraine dismantles hi-tech contraband ring that used drones for smuggling cigarettes and monitoring border patrols
Ukrainian border guards successfully apprehended a smuggling group from Volyn that employed drones for contraband smuggling and border patrol surveillance.
Unaware of their role, ordinary Ukrainian citizens contributed to the classified Black Box initiative, leading to the covert development and production of the Beaver suicide drone with an impressive 800 km range
Russian authorities, including Moscow Mayor Sergey Sobyanin and the Ministry of Defense, assert the successful interception of 21 UAVs en route to Moscow, neutralizing them in various regions with no reported casualties or damage.
Ukrainian Deputy PM Mykhailo Fedorov reports thousands of drones produced monthly in Ukraine, intending to outdo Russian UAV advances.
Multiple reports indicate that Russia's combat drone operator training center in Donetsk, occupied by Russian forces since 2014, was hit by an alleged Ukrainian HIMARS strike. Russia's TASS disclosed the facility earlier this year.
The Ukroboronprom CEO confirms mass productions of Ukrainian "kamikaze" drones with a combat range of up to 1,000 km. Additionally, the company supports the production of FPV drones from private firms, further enhancing Ukraine's drone capabilities.
Russo-Ukrainian war, day 618: Russian mil HQ hit in Kherson Oblast; Ukraine “drone army” UAVs responsible for 35% of Russia tank losses
Ukraine's President Zelenskyy appoints Colonel Serhii Lupanchuk as Special Operations Forces chief. "Army of Drones" UAVs destroy Russian tanks. Netherlands provides $530 million military aid. Russo-Ukrainian war remains stalemated. Moldova excludes pro-Russian party from local elections.
From 2-30 October, the Ukrainian military, utilizing UAVs provided by the "Army of Drones" project, destroyed 175 Russian tanks, comprising a significant portion of the 473 total tanks destroyed during this period.
Ukraine seeks to ramp up drone production to tens of thousands per month by year's end to strengthen defense capabilities, Ukraine's Strategic Industries Minister says.
Antonov, Ukraine's aircraft firm, is branching into drones following Russia's invasion, aiming to both diversify from cargo planes and position Ukraine as a top drone tech hub, Reuters says.
Ukrainian "kamikaze" drones attacked a Russian military airfield in Kursk Oblast bordering Ukraine, according to sources in Ukraine's security service.