[
  {
    "id": "SULT1A1_active",
    "group": "hair",
    "desc": "SULT1A1 bioactivation competence (minoxidil-type response)",
    "index": 0
  },
  {
    "id": "AR_antagonist",
    "group": "hair",
    "desc": "Androgen receptor antagonism",
    "index": 1
  },
  {
    "id": "SRD5A1_inhibitor",
    "group": "hair",
    "desc": "5-alpha reductase type 1 inhibition",
    "index": 2
  },
  {
    "id": "Wnt_bcatenin_activator",
    "group": "hair",
    "desc": "Wnt/beta-catenin pathway activation",
    "index": 3
  },
  {
    "id": "FGF7_KGF_active",
    "group": "hair",
    "desc": "KGF/FGF7 fibroblast pathway activity",
    "index": 4
  },
  {
    "id": "hair_growth_lit_positive",
    "group": "hair",
    "desc": "Literature-curated hair-growth positive",
    "index": 5
  },
  {
    "id": "NR-AR",
    "group": "tox",
    "desc": "Tox21 androgen receptor agonist/antagonist",
    "index": 6
  },
  {
    "id": "NR-AR-LBD",
    "group": "tox",
    "desc": "Tox21 androgen receptor LBD",
    "index": 7
  },
  {
    "id": "NR-AhR",
    "group": "tox",
    "desc": "Tox21 aryl hydrocarbon receptor",
    "index": 8
  },
  {
    "id": "NR-Aromatase",
    "group": "tox",
    "desc": "Tox21 aromatase inhibition",
    "index": 9
  },
  {
    "id": "NR-ER",
    "group": "tox",
    "desc": "Tox21 estrogen receptor agonist/antagonist",
    "index": 10
  },
  {
    "id": "NR-ER-LBD",
    "group": "tox",
    "desc": "Tox21 estrogen receptor LBD",
    "index": 11
  },
  {
    "id": "NR-PPAR-gamma",
    "group": "tox",
    "desc": "Tox21 PPAR-gamma",
    "index": 12
  },
  {
    "id": "SR-ARE",
    "group": "tox",
    "desc": "Tox21 antioxidant response element",
    "index": 13
  },
  {
    "id": "SR-ATAD5",
    "group": "tox",
    "desc": "Tox21 ATAD5 DNA damage response",
    "index": 14
  },
  {
    "id": "SR-HSE",
    "group": "tox",
    "desc": "Tox21 heat shock response",
    "index": 15
  },
  {
    "id": "SR-MMP",
    "group": "tox",
    "desc": "Tox21 mitochondrial membrane potential disruption",
    "index": 16
  },
  {
    "id": "SR-p53",
    "group": "tox",
    "desc": "Tox21 p53 stress response",
    "index": 17
  },
  {
    "id": "skin_sensitizer",
    "group": "safety",
    "desc": "Skin sensitization positive (LLNA/KeratinoSens-informed)",
    "index": 18
  },
  {
    "id": "cosing_prohibited",
    "group": "safety",
    "desc": "Matches EU CosIng Annex II prohibited/restricted substance",
    "index": 19
  },
  {
    "id": "irritancy_alert",
    "group": "safety",
    "desc": "Structural/class-based skin irritancy alert",
    "index": 20
  }
]