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LICENSE ADDED
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+ CC0 1.0 Universal
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+
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+ The person who associated a work with this deed has dedicated the work to the
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+ public domain by waiving all of his or her rights to the work worldwide under
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+ copyright law, including all related and neighboring rights, to the extent
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+ allowed by law.
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+
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+ Full text: https://creativecommons.org/publicdomain/zero/1.0/legalcode
README.md CHANGED
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- ---
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- license: cc0-1.0
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ license: cc0-1.0
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+ pretty_name: "CP-BG-Bench JUMP C (raw cell crop)"
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+ size_categories:
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+ - 100K<n<1M
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+ task_categories:
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+ - image-feature-extraction
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+ tags:
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+ - cell-painting
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+ - microscopy
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+ - representation-learning
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+ - single-cell
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+ - biology
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+ - jump-cp
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+ configs:
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+ - config_name: default
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+ data_files:
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+ - split: train
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+ path: data/shard-*.tar
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+ ---
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+
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+ # CP-BG-Bench: JUMP view C (raw cell crop)
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+
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+ This dataset is one of four paired views of the same single-cell tiles from
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+ the JUMP-CP Cell Painting consortium, prepared for the CP-BG-Bench evaluation
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+ framework.
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+
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+ The four views — C (raw crop), S (background-masked crop), CD (density-augmented),
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+ SD (background-masked + density-augmented) — are released as separate
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+ repositories. They are **row-aligned**: each `row_key` exists in all four
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+ views and refers to the same underlying cell. Each view ships the same
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+ schema (cell + mask + metadata); only the `cell.bin` content differs.
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+
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+ This repository contains view **C**: raw cell crop.
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+
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+ ## Format
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+
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+ WebDataset tar shards. Each cell occupies one sample with four files sharing a
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+ key:
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+
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+ - `{key}.cell.bin` — raw uint8 bytes, shape `(5, 224, 224)`, channel-first.
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+ View-specific image content (raw / background-masked / density-augmented).
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+ - `{key}.mask.bin` — raw uint8 bytes, shape `(2, 224, 224)`, channel-first.
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+ Segmentation mask (`[nucleus, cell]`); identical across all four views.
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+ - `{key}.json` — per-cell metadata (see below).
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+
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+ Note: the binary blobs are **raw bytes**, not PNG/NPY. Decode with:
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+
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+ ```python
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+ import numpy as np
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+ cell = np.frombuffer(cell_bytes, dtype=np.uint8).reshape((5, 224, 224))
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+ mask = np.frombuffer(mask_bytes, dtype=np.uint8).reshape((2, 224, 224))
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+ ```
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+
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+ ## Channels
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+
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+ The 5 channels are stored in this order:
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+
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+ | index | label | stain |
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+ |---|---|---|
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+ | 0 | DNA | Hoechst 33342 |
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+ | 1 | AGP | Phalloidin + WGA |
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+ | 2 | ER | Concanavalin A |
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+ | 3 | Mito | MitoTracker Deep Red |
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+ | 4 | RNA | SYTO 14 |
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+
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+ > **Note: this on-disk order is `[DNA, AGP, ER, Mito, RNA]`, which differs
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+ > from both the JUMP-CP v2 publication order `[DNA, ER, RNA, AGP, Mito]` and
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+ > the Recursion RxRx order `[DNA, ER, AGP, RNA, Mito, ...]`.** Code that
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+ > assumes a particular order without checking will feed the wrong stain to
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+ > downstream channel slots. A machine-readable `channels.json` is provided at
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+ > the repo root; please use it. The CP-BG-Bench framework resolves channels
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+ > by name and is robust to per-dataset reorderings.
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+
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+
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+ The 2 mask channels are stored in this order:
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+
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+ | index | label | description |
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+ |---|---|---|
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+ | 0 | nucleus | binary nucleus segmentation mask |
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+ | 1 | cell | binary whole-cell segmentation mask |
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+
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+ Masks are uint8 with values in `{0, 255}` (or another non-zero label).
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+ A machine-readable `channels.json` is provided at the repo root.
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+
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+
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+ ## Metadata fields
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+
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+ Each `.json` sidecar contains:
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+
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+ | Field | Type | Description |
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+ |---|---|---|
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+ | `row_key` | str | Stable cell identifier (`source__date_run__plate__well__tile__id`) |
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+ | `source` | str | JUMP partner code (e.g. `source_4`) |
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+ | `batch` | str | Batch identifier (= `source` for JUMP-CP) |
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+ | `plate` | str | JUMP plate identifier |
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+ | `well` | str | Well coordinate (e.g. `B02`) |
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+ | `tile` | str | Site index within well |
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+ | `id_local` | int | Per-tile cell index |
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+ | `perturbation` | str | Compound InChIKey (= `Metadata_InChIKey`) |
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+ | `Metadata_InChIKey` | str | Public PubChem-derivable compound ID |
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+ | `Metadata_PlateType` | str | `TARGET2` or `COMPOUND` |
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+ | `nuc_area`, `cyto_area`, `nuc_cyto_ratio` | num | Single-cell QC features |
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+ | `n_cells_in_fov`, `n_cells_scaled` | num | Local density features |
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+
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+ A flat `metadata.parquet` covering all rows (with `shard_index` and
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+ `key_in_shard` columns) is provided at the repo root for fast subsetting
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+ without scanning the tar shards.
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+
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+ ## Statistics
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+
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+ - Total cells: 645,390
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+ - Shards: 43
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+ - Approximate shard size: ~5.3 GB
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+ - Plate types: COMPOUND: 445,968, TARGET2: 199,422
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+ - Sources (JUMP partners): 10
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+ - Plates: 900
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+ - Unique perturbations (InChIKeys): 1467
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+
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+ ## Splits
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+
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+ A natural held-out batch is `source_4` (21,177 cells), used in the
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+ CP-BG-Bench cross-batch retrieval evaluation. Filter with:
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+
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+ ```python
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+ ds = ds.filter(lambda r: r["source"] == "source_4")
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+ ```
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+
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+ ## Pairing across views
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+
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+ The four CP-BG-Bench JUMP repos share `row_key` exactly. To use a paired
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+ dataloader, load all four and join on `row_key` (the `metadata.parquet` files
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+ make this cheap):
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+
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+ - `<anon-org>/jump-c-target2` (this view: C)
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+ - `<anon-org>/jump-s-target2`
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+ - `<anon-org>/jump-cd-target2`
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+ - `<anon-org>/jump-sd-target2`
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+
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+ ## Shard ordering
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+
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+ - Rows are written in the order they appear in the source HF Datasets
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+ directory. Shuffle at load time (PyTorch `DataLoader(shuffle=True)` or
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+ `webdataset.WebDataset(...).shuffle(N)`); shards are not pre-shuffled.
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+ - `(shard_index, key_in_shard)` for every row is in `metadata.parquet`.
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+
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+ ## License
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+
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+ CC0 1.0 Universal. Underlying JUMP-CP data is released by the JUMP-Cell
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+ Painting consortium under CC0 1.0.
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+
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+ ## Citation
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+
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+ Anonymous submission to NeurIPS 2026 Datasets & Benchmarks Track.
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+
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+ For the underlying JUMP-CP data, please cite the JUMP-CP consortium release.
channels.json ADDED
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+ {
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+ "view": "C",
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+ "view_description": "raw cell crop",
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+ "files": {
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+ "cell.bin": {
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+ "channels": [
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+ "DNA",
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+ "AGP",
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+ "ER",
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+ "Mito",
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+ "RNA"
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+ ],
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+ "stains": {
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+ "DNA": "Hoechst 33342",
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+ "AGP": "Phalloidin + WGA",
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+ "ER": "Concanavalin A",
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+ "Mito": "MitoTracker Deep Red",
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+ "RNA": "SYTO 14"
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+ },
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+ "shape": [
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+ 5,
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+ 224,
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+ 224
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+ ],
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+ "dtype": "uint8",
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+ "layout": "channel-first (C, H, W)",
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+ "encoding": "raw bytes; np.frombuffer(blob, dtype=np.uint8).reshape(5, 224, 224)"
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+ },
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+ "mask.bin": {
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+ "channels": [
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+ "nucleus",
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+ "cell"
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+ ],
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+ "shape": [
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+ 2,
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+ 224,
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+ 224
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+ ],
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+ "dtype": "uint8",
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+ "layout": "channel-first (C, H, W)",
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+ "encoding": "raw bytes; np.frombuffer(blob, dtype=np.uint8).reshape(2, 224, 224)"
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+ }
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+ },
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+ "notes": [
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+ "On-disk channel order [DNA, AGP, ER, Mito, RNA] differs from the JUMP-CP v2 publication order [DNA, ER, RNA, AGP, Mito] and from the Recursion RxRx order [DNA, ER, AGP, RNA, Mito, ...].",
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+ "Loaders must remap by name, not by index, when combining JUMP with other Cell Painting datasets.",
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+ "Mask channels are [nucleus, cell] \u2014 both binary uint8."
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+ ]
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+ }
croissant.json ADDED
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+ {
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+ "@context": {
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+ "@language": "en",
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+ "@vocab": "https://schema.org/",
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+ "cr": "http://mlcommons.org/croissant/",
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+ "rai": "http://mlcommons.org/croissant/RAI/",
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+ "data": {
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+ "@id": "cr:data",
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+ "@type": "@json"
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+ },
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+ "dct": "http://purl.org/dc/terms/",
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+ "examples": {
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+ "@id": "cr:examples",
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+ "@type": "@json"
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+ },
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+ "extract": "cr:extract",
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+ "field": "cr:field",
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+ "fileObject": "cr:fileObject",
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+ "fileSet": "cr:fileSet",
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+ "format": "cr:format",
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+ "includes": "cr:includes",
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+ "isLiveDataset": "cr:isLiveDataset",
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+ "jsonPath": "cr:jsonPath",
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+ "key": "cr:key",
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+ "md5": "cr:md5",
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+ "parentField": "cr:parentField",
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+ "path": "cr:path",
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+ "recordSet": "cr:recordSet",
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+ "references": "cr:references",
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+ "regex": "cr:regex",
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+ "repeated": "cr:repeated",
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+ "replace": "cr:replace",
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+ "sc": "https://schema.org/",
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+ "separator": "cr:separator",
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+ "source": "cr:source",
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+ "subField": "cr:subField",
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+ "transform": "cr:transform"
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+ },
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+ "@type": "sc:Dataset",
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+ "name": "cp-bg-bench-jump-c",
41
+ "description": "CP-BG-Bench JUMP view C (raw cell crop). Single-cell Cell Painting tiles from the JUMP-CP consortium, released as one of four paired views (C, S, CD, SD) for the CP-BG-Bench evaluation framework.",
42
+ "conformsTo": "http://mlcommons.org/croissant/1.0",
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+ "license": "https://creativecommons.org/publicdomain/zero/1.0/",
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+ "url": "https://huggingface.co/datasets/anonymous/cp-bg-bench-jump",
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+ "creator": {
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+ "@type": "Organization",
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+ "name": "anonymous"
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+ },
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+ "publisher": {
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+ "@type": "Organization",
51
+ "name": "anonymous"
52
+ },
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+ "citeAs": "Anonymous submission to NeurIPS 2026 Datasets & Benchmarks Track.",
54
+ "datePublished": "2026-05-05",
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+ "version": "1.0.0",
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+ "keywords": [
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+ "Cell Painting",
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+ "JUMP-CP",
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+ "single-cell",
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+ "microscopy",
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+ "representation learning"
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+ ],
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+ "rai:dataCollection": "Single-cell tiles were extracted from the JUMP-CP consortium image release (Chandrasekaran et al.). Cells were segmented at the FOV level, cropped at 150x150 px around the segmented centroid, and resized to 224x224. Per-FOV percentile normalisation was applied before quantisation to uint8.",
64
+ "rai:dataPreprocessingProtocol": "QC filters on (nuc_area, cyto_area, nuc_cyto_ratio) at percentiles [0.025, 0.975]. Per-(perturbation x experimental batch) cell cap of approximately 100 cells. Density-augmented views (CD, SD) encode per-cell local FOV density.",
65
+ "rai:dataUseCases": "Benchmarking representation learning models on single-cell morphology under perturbation; evaluating cell-vs-background contributions to learned representations.",
66
+ "rai:dataLimitations": "Cells from one cell line (U2OS), one assay (Cell Painting), one consortium (JUMP-CP). Channel order is the standard JUMP order and should be confirmed against the upstream pipeline before use. Quantisation to uint8 was applied during tile extraction.",
67
+ "rai:dataBiases": "Compound coverage follows the JUMP-CP Target2 + Compound plate design and is biased toward annotated chemical probes and drug-like molecules. Source (JUMP partner) is a known major covariate that should be controlled in evaluation.",
68
+ "rai:annotationsPerItem": "0",
69
+ "rai:personalSensitiveInformation": "None",
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+ "distribution": [
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+ {
72
+ "@type": "cr:FileSet",
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+ "@id": "shards",
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+ "name": "shards",
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+ "description": "WebDataset tar shards.",
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+ "containedIn": {
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+ "@id": "https://huggingface.co/datasets/anonymous/cp-bg-bench-jump"
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+ },
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+ "encodingFormat": "application/x-tar",
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+ "includes": "data/shard-*.tar"
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+ }
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+ ],
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+ "recordSet": [
84
+ {
85
+ "@type": "cr:RecordSet",
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+ "@id": "cells",
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+ "name": "cells",
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+ "description": "One row per single-cell tile.",
89
+ "field": [
90
+ {
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+ "@type": "cr:Field",
92
+ "@id": "cells/row_key",
93
+ "name": "row_key",
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+ "dataType": "sc:Text",
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+ "description": "Stable per-cell identifier."
96
+ },
97
+ {
98
+ "@type": "cr:Field",
99
+ "@id": "cells/cell",
100
+ "name": "cell.bin",
101
+ "dataType": "sc:ImageObject",
102
+ "description": "Raw uint8 bytes, shape (5, 224, 224), channel-first. View-specific image content."
103
+ },
104
+ {
105
+ "@type": "cr:Field",
106
+ "@id": "cells/mask",
107
+ "name": "mask.bin",
108
+ "dataType": "sc:ImageObject",
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+ "description": "Raw uint8 bytes, shape (2, 224, 224), channel-first. Segmentation mask (nucleus, cell)."
110
+ },
111
+ {
112
+ "@type": "cr:Field",
113
+ "@id": "cells/perturbation",
114
+ "name": "perturbation",
115
+ "dataType": "sc:Text",
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+ "description": "Compound InChIKey."
117
+ },
118
+ {
119
+ "@type": "cr:Field",
120
+ "@id": "cells/source",
121
+ "name": "source",
122
+ "dataType": "sc:Text",
123
+ "description": "JUMP partner identifier."
124
+ },
125
+ {
126
+ "@type": "cr:Field",
127
+ "@id": "cells/plate",
128
+ "name": "plate",
129
+ "dataType": "sc:Text",
130
+ "description": "JUMP plate identifier."
131
+ },
132
+ {
133
+ "@type": "cr:Field",
134
+ "@id": "cells/Metadata_PlateType",
135
+ "name": "Metadata_PlateType",
136
+ "dataType": "sc:Text",
137
+ "description": "TARGET2 or COMPOUND."
138
+ }
139
+ ]
140
+ }
141
+ ]
142
+ }
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