Unnamed: 0 int64 0 1.1k | MICROBE stringlengths 2 45 | DISEASE stringlengths 2 53 | EVIDENCE stringlengths 58 610 | RELATION stringclasses 4
values | QUESTIONS stringlengths 44 112 |
|---|---|---|---|---|---|
100 | Blautia coccoides | systemic lupus erythematosus | No previous association of Blautia coccoides (which was depleted in our na?ve group) with RA was reported; nonetheless, it was shown that enriching the gut microbiota of systemic lupus erythematosus patients with Blautia coccoides, together with Ruminococcus obeum and Bifidobacterium bifidum, improved the inflammatory ... | relate | What is the relationship between Blautia coccoides and systemic lupus erythematosus? |
101 | Fusobacterium | oral cancers | [33] in their study where aerobic bacterial species Haemophilus, Enterobacteriaceae and Streptococcus and anaerobic bacterial species such as Veillonella, Fusobacterium, Prevotella, Porphyromonas, Actinomyces and Clostridium were detected more frequently in oral cancers than in normal oral mucosa. | relate | What is the relationship between Fusobacterium and oral cancers? |
102 | Dialister invisus | CD | Joossens et al.showed a decrease in F. prausnitzii, Dialister invisus, an uncharacterized species of Clostridium group XIVa, in Bifidobacterium adolescents, in CD patients compared to healthy controls [28]. | negative | What is the relationship between Dialister invisus and CD? |
103 | Klebsiella oxytoca | hemorrhagic colitis | Of note, antibiotic-associated colitis could be caused also by other pathogens, like Klebsiella oxytoca, the causative agent of antibiotic-associated hemorrhagic colitis (AAHC). | positive | What is the relationship between Klebsiella oxytoca and hemorrhagic colitis? |
104 | Porphyromonas asaccharolytica | CRC-related | For example, Zeller and Feng et al.showed that Porphyromonas asaccharolytica, Peptostreptococcus stomatis, Fusobacterium vincentii, and Fusobacterium animalis were predictive in the early diagnosis of colorectal cancer, which are among the tops of our list; in particular, F. nucleatum is a common CRC-related species wh... | relate | What is the relationship between Porphyromonas asaccharolytica and CRC-related? |
105 | Streptococcus bovis (S. bovis) | colorectal cancer | The pathogens that appear to be primarily involved in the pathogenesis of colorectal cancer [78] are Streptococcus bovis (S. bovis) [79], Hp [80], Bacteroides fragilis (B. fragilis) [81], Enterococcus faecalis (E. faecalis) [82], Clostridium septicum (C. septicum) [83], Fusobacterium spp. | positive | What is the relationship between Streptococcus bovis (S. bovis) and colorectal cancer? |
106 | Candida albicans | HIV-infected | In HIV-infected patients, inflammatory markers were concurrent with an altered fecal microbiome composition featuring increased abundances of Pseudomonas aeruginosa and Candida albicans and decreased abundances of Lactobacilli and Bifidobacteria (Gori et al., 2008). | positive | What is the relationship between Candida albicans and HIV-infected? |
107 | Helicobacter pylori | ulcer | It is known that Helicobacter pylori plays an important role in the pathogenesis of ulcer, while Firmicutes are involved in obesity (Yu et al., 2014). | negative | What is the relationship between Helicobacter pylori and ulcer? |
108 | Escherichia coli | diarrhea | In 80% to 85% of cases, diarrhea is due to pathogenic bacteria [Escherichia coli (E. coli), enteropathogenic, Campylobacter jejuni, Shigella, Salmonella, Yersinia enterocolitica]. | positive | What is the relationship between Escherichia coli and diarrhea? |
109 | Streptococcus | respiratory tract infections | For instance, the six dominant genera in the upper airway microbiota in children have been shown to be Haemophilus, Streptococcus, Corynebacterium, Staphylococcus, Moraxella, and Alloiococcus [3], members of which are commonly implicated in respiratory tract infections. | relate | What is the relationship between Streptococcus and respiratory tract infections? |
110 | Peptostreptococcus stomatis | colorectal cancer | Several species of Peptostreptococcus and Parvimonas were extensively enriched in cancer samples, including Peptostreptococcus stomatis and Parvimonas micra, both of which are reportedly related to colorectal cancer. | relate | What is the relationship between Peptostreptococcus stomatis and colorectal cancer? |
111 | ETEC | diarrhea | Enterotoxigenic Escherichia coli (ETEC) causes hundreds of millions of cases of diarrhea annually, particularly in developing countries | positive | What is the relationship between ETEC and diarrhea? |
112 | Enterococcus | CHB | Specifically, patients with CHB and cirrhosis exhibit dramatically decreased Bifidobacteria and Lactobacillus levels, while Enterococcus and Enterobacteriaceae levels are significantly increased compared to healthy people. | positive | What is the relationship between Enterococcus and CHB? |
113 | Gemella sanguinis | tumor | The unnamed cultivable taxon, Streptococcus sp. oral taxon 058, and named cultivable bacterial species, Gemella haemolysans, Gemella morbillorum, Gemella sanguinis, Johnsonella ignava, Peptostreptococcus stomatis, Streptococcus gordonii, Streptococcus parasanguinis I, Streptococcus salivarius were highly associated to ... | relate | What is the relationship between Gemella sanguinis and tumor? |
114 | Streptococcus thermophilus | antibiotic-associated diarrhea (AAD) in infants | Diet supplementation with Bifidobacterium lactis and Streptococcus thermophilus was shown to reduce the frequency of antibiotic-associated diarrhea (AAD) in infants. | negative | What is the relationship between Streptococcus thermophilus and antibiotic-associated diarrhea (AAD) in infants? |
115 | Porphyromonas gingivalis | chronic periodontitis | Among periodontopathogenic bacteria, (Porphyromonas gingivalis), a gram-negative anaerobe and one of the most important pathogens in chronic periodontitis, has the ability for co-aggregation not only with (Fusobacterium nucleatum), but also with early colonizers (such as Streptococcus gordonii) [48], which could help e... | positive | What is the relationship between Porphyromonas gingivalis and chronic periodontitis? |
116 | Psae | chronic obstructive lung disease | Furthermore, patients suffering from chronic respiratory morbidities including chronic obstructive lung disease, bronchiectasis, or cystic fibrosis are prone to chronic Psae infection, further exacerbating the underlying disease (3). | positive | What is the relationship between Psae and chronic obstructive lung disease? |
117 | Streptococcus pneumoniae | pneumonia | Streptococcus pneumoniae, the pneumococcus, causes several serious and often life-threatening infections including meningitis, pneumonia and bacteraemia. | positive | What is the relationship between Streptococcus pneumoniae and pneumonia? |
118 | Bacteroides vulgatus | cancer | Through epithelial injury and inflammation, chronic infections (viruses, Helicobacter pylori and other Helicobacter spp., Bacteroides fragilis, Bacteroides vulgatus, Escherichia coli, Citrobacter rodentium, Citrobacter freundii, and protozoa) are linked to carcinogenesis with approximately 18% of the worldwide cancer b... | relate | What is the relationship between Bacteroides vulgatus and cancer? |
119 | Bacteroides intestinalis | T2D | Accordingly, in investigations that analyzed this genus on the species level, Bacteroides intestinalis, Bacteroides 20?3 and Bacteroides vulgatus were decreased in T2D patients and Bacteroides stercoris were enriched after sleeve gastrectomy (SG) surgery in T2D patients with diabetes remission [5,11,17,24]. | negative | What is the relationship between Bacteroides intestinalis and T2D? |
120 | Enterococcus | fatal nosocomial infections | In addition, Enterococcus often develop antibiotic resistance due to abuse of antibiotics and may cause fatal nosocomial infections in humans (40,56,57). | positive | What is the relationship between Enterococcus and fatal nosocomial infections? |
121 | Fusobacterium | IBD | In colorectal cancer patients, treatment with Lactobacillus acidophilus, Bifidobacterium longum, and Enterococcus faecalis decreased the abundance of pathogenic Fusobacterium, the prevalence of which is associated with both IBD and colorectal cancer. | positive | What is the relationship between Fusobacterium and IBD? |
122 | Bifidobacterium adolescentis | cancer | Another study reported that Bifidobacterium adolescentis SPM0212 significantly impeded cancer growth on three different cell lines Caco-2, SW 480 and HT-29. | negative | What is the relationship between Bifidobacterium adolescentis and cancer? |
123 | Parabacteroides | GDM | At the genus level, GDM patients had a significantly higher abundance of Parabacteroides, Megamonas, and Phascolarctobacterium, while healthy controls were significantly enriched for Ruminiclostridium, Roseburia, Eggerthella, Fusobacterium, Haemophilus, Mitsukella, and Aggregatibacter (Fig?1b). | positive | What is the relationship between Parabacteroides and GDM? |
124 | Pg | arthritis | Oral infection by Pg worsens paw swelling, bone loss and synovitis, and increases proinflammatory cytokine expression in collagen-induced arthritis (CIA) and collagen antibody-induced arthritis mouse model. | positive | What is the relationship between Pg and arthritis? |
125 | Bacteroides fragilis | antibiotic-associated diarrhea | Figure 5 Bacteroides fragilis ZY-312 improves gut barrier integrity in antibiotic-associated diarrhea (AAD) rats. | negative | What is the relationship between Bacteroides fragilis and antibiotic-associated diarrhea? |
126 | Methanobrevibacter smithii | obesity | In particular, a reduction in Methanobrevibacter smithii has been implicated in obesity [56]. | negative | What is the relationship between Methanobrevibacter smithii and obesity? |
127 | Lactobacillus acidophilus | diabetes | Yadav et al.showed that a probiotic dahi-supplemented diet, containing Lactobacillus acidophilus and Lactobacillus casei, significantly delayed the onset of glucose intolerance, hyperglycemia, hyperinsulinemia, dyslipidemia, and oxidative stress in high fructose-fed diabetic rats, thus lowering the risk of diabetes and... | negative | What is the relationship between Lactobacillus acidophilus and diabetes? |
128 | Ruminococcus | inflammatory bowel disease (IBD) | In addition, Ruminococcus, a genus of class Clostridia which pointing to an energy metabolism dysfunction, was identified as one of characteristic genus of individuals with inflammatory bowel disease (IBD). | relate | What is the relationship between Ruminococcus and inflammatory bowel disease (IBD)? |
129 | Prevotella intermedia | chronic periodontitis | The results of our study confirmed this association, and showed that this Gram-negative rod was isolated from 68% of patients with chronic periodontitis, but its participation in the microbiota was very reduced, always smaller than others pathogens like Prevotella intermedia, Porphyromonas gingivalis and particularly F... | relate | What is the relationship between Prevotella intermedia and chronic periodontitis? |
130 | Streptococcus mutans (S. mutans) | dental caries | The primary pathogens associated with dental caries are Streptococcus mutans (S. mutans) and Streptococcus sobrinus (S. sobrinus), the Mutans Streptococci (MS). | relate | What is the relationship between Streptococcus mutans (S. mutans) and dental caries? |
131 | Porphyromonas gingivalis | Alzheimer?s disease | In Alzheimer?s disease, inhibitors of the gingipains proteases secreted by Porphyromonas gingivalis were able to reduce infection by this species in the brain as well as amyloid-? production and neuroinflammation. | negative | What is the relationship between Porphyromonas gingivalis and Alzheimer?s disease? |
132 | Streptococcus | oral cancer | Researchers have also found that specific bacterial taxa, such as Veillonella, Fusobacterium, Prevotella, Porphyromonas, Actinomyces, Clostridium, Haemophilus, Enterobacteriaceae, and Streptococcus spp., are linked to oral cancer and epithelial precursor lesions25. | relate | What is the relationship between Streptococcus and oral cancer? |
133 | Lactobacillus | LC | [13] have found that the number of beneficial bacteria such as Bifidobacterium and Lactobacillus significantly decreases, while the levels of harmful bacteria such as Enterobacteriaceae and Enterococcus significantly increase in CHB and LC. | negative | What is the relationship between Lactobacillus and LC? |
134 | Veillonella | colitis | To this regard, it has been reported that an increased amount of Veillonella is associated with higher levels of gut inflammation and the development of colitis and Crohn?s disease; on the contrary, an increased the abundance of the Prevotella genus has been described as a shield against inflammation and non-infectious... | positive | What is the relationship between Veillonella and colitis? |
135 | Escherichia coli | UC | In a study by Sokol et al., [44], the biodiversity of the active microbiota was shown to be lower for UC patients than for healthy controls and Escherichia coli (or related Enterobacteriaceae) were significantly associated with UC. | relate | What is the relationship between Escherichia coli and UC? |
136 | Staphylococcus aureus | septicemia | Introduction Staphylococcus aureus colonizes human mucosa and skin and is a major human pathogen that causes a strikingly broad range of infections, ranging from relatively minor skin abscesses to potentially life-threatening pneumonia, osteomyelitis, endocarditis, necrotizing fasciitis, septicemia, and toxic shock syn... | positive | What is the relationship between Staphylococcus aureus and septicemia? |
137 | Streptococcus | KD | Indeed, Streptococcus spp. were highly abundant in the gut microbiotas of some of the KD patients; for example, 77% of the bacterial reads of one KD patient (the acute phase in P7) were from Streptococcus. | positive | What is the relationship between Streptococcus and KD? |
138 | Burkholderia cepacia | CF | Burkholderia cepacia complex (Bcc) is a group of opportunistic pathogens, with at least 20 distinct genomovars/species [1], believed to be associated with poor prognosis and patient-to-patient transmissibility in cystic fibrosis (CF). | relate | What is the relationship between Burkholderia cepacia and CF? |
139 | Porphyromonas gingivalis | rheumatoid arthritis | For example, the Porphyromonas gingivalis genome, which represents organisms implicated in periodontal disease and has been linked to rheumatoid arthritis [36] and heart disease [37], recruits a relatively large fraction of reads from all individuals (1.68%). | relate | What is the relationship between Porphyromonas gingivalis and rheumatoid arthritis? |
140 | BA | diarrhea and inflammation | Among them, Bacillus amyloliquefaciens (BA) has gained more attention, and emerging evidence has identified its health-beneficial properties in the treatment of intestinal disorders, such as diarrhea and inflammation. | negative | What is the relationship between BA and diarrhea and inflammation? |
141 | Lactobacillus reuteri | obesity | This finding is concurrent with the findings in non-pregnant individuals as strains of Eisenbergiella and Lactobacillus reuteri have previously been associated with obesity [56, 57]. | relate | What is the relationship between Lactobacillus reuteri and obesity? |
142 | Pseudomonas aeruginosa | IPF | Specifically, the authors observed pathogen growth (e.g., Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae, Moraxella catarrhalis, Pseudomonas aeruginosa and Proteus mirabilis) in 8/22 (36%) IPF patients, suggesting that occult bacterial infection may contribute to the development of IPF. | positive | What is the relationship between Pseudomonas aeruginosa and IPF? |
143 | Prevotella salivae | CRS | Lastly, one Prevotella ASV (Prevotella 13, whose sequence was identical to a V4 sequence of Prevotella salivae) was more prevalent in the nasopharynx of CRS patients than in that of the healthy controls (11% of control samples and 25% of CRS patient samples). | positive | What is the relationship between Prevotella salivae and CRS? |
144 | Escherichia coli Nissle 1917 | UC | With regard to UC, it was shown that the use of Escherichia coli Nissle 1917 strain for patients with UC was effective in maintaining remission as mesalazine therapy alone. | negative | What is the relationship between Escherichia coli Nissle 1917 and UC? |
145 | Streptococcus | IBD | A previous study showed that the genus Veillonella was significantly higher in the salivary microbiota of inflammatory bowel disease (IBD) patients than in that of HCs, while the genus Streptococcus was significantly lower in the salivary microbiota of IBD patients than in that of HCs [12]. | negative | What is the relationship between Streptococcus and IBD? |
146 | Streptococcus | ulcerative colitis | In addition, the Lactobacillus, Streptococcus and Pseudomanas counts were significantly decreased and that for Enterobacteriacceae was significantly increased in patients with ulcerative colitis. | negative | What is the relationship between Streptococcus and ulcerative colitis? |
147 | Fusobacterium necrophorum | CRC | A number of studies have revealed a link between Fusobacterium and CRC [37,38], observation supported by the 16S DNA sequenced analysis of colorectal microbe, which showed high proportion of Fusobacterium genus: Fusobacterium nucleatum, Fusobacterium mortiferum and Fusobacterium necrophorum in tumor tissue, changes acc... | relate | What is the relationship between Fusobacterium necrophorum and CRC? |
148 | Tannerella forsythia | periodontitis | Likewise, species associated with periodontitis showed increased evidence for transmission (p=0.002), though this signal was mostly due to mildly periodontic species, while core drivers, such as Tannerella forsythia, Treponema denticola and Porphyromonas gingivalis (Socransky et al., 1998), showed little or no indicati... | relate | What is the relationship between Tannerella forsythia and periodontitis? |
149 | Anaerotruncus colihominis | bacteremia | Though its major end-products include acetate and butyrate, generally regarded as beneficial metabolites, the clinical investigation of Anaerotruncus colihominis demonstrated its critical role in bacteremia. | relate | What is the relationship between Anaerotruncus colihominis and bacteremia? |
150 | Helicobacter pylori | intestinal metaplasia | The strongest known risk factor for this devastating disease is infection with Helicobacter pylori, which drives the development of premalignant lesions (such as gastric atrophy, intestinal metaplasia, and dysplasia) that can lead to gastric cancer (Fig 1). | positive | What is the relationship between Helicobacter pylori and intestinal metaplasia? |
151 | Escherichia | urinary tract infection (UTI) | Among the 25 increased genera, many anaerobic bacteria, such as Gardnerella, Prevotella, and Atopobium, are the main pathogens for bacterial vaginosis (BV), while the abundance of many aerobic bacteria, such as Escherichia, Enterococcus, Streptococcus, and Corynebacterium, are closely related to the risk of aerobic vag... | relate | What is the relationship between Escherichia and urinary tract infection (UTI)? |
152 | Escherichia coli | ileal CD | Recently, another microorganism, Escherichia coli, has been under investigation and associated with ileal CD [35], but there is no evidence that antibiotic treatment against coliforms is efficacious in curing IBD patients. | relate | What is the relationship between Escherichia coli and ileal CD? |
153 | Bacteroides fragilis | cardiovascular disorders | Vitamin-K-producing gut bacteria namely Bacteroides fragilis, Eubacterium lentum, Enterobacter agglomerans, Serratia marcescens, and Enterococcus faecium (Fernandez and Collins, 1987; Cooke et al., 2006) anaerobically synthesize vitamin K2 (menaquinone) which is essential in decreasing vascular calcification, elevating... | negative | What is the relationship between Bacteroides fragilis and cardiovascular disorders? |
154 | Lactobacillus rhamnosus GG | sepsis | In a review by Doron and Syndman examining the adverse events associated with probiotics, at least eight cases of bacteremia were associated with lactobacilli, nine cases of sepsis with Saccharomyces boulardii, Lactobacillus rhamnosus GG, Bacillus subtilis, Bifidobacterium breve, or combination probiotics, and two case... | relate | What is the relationship between Lactobacillus rhamnosus GG and sepsis? |
155 | Chlamydia trachomatis | cervical cancer | In the last two decades, significant evidence has emerged implicating bacteria in the aetiology of some cancer types such as Helicobacter pylori in gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphomas, Chlamydia trachomatis in cervical cancer, Salmonella typhi in gallbladder cancer and both Bacteroides... | relate | What is the relationship between Chlamydia trachomatis and cervical cancer? |
156 | Escherichia coli | colorectal cancer | Fusobacterium nucleatum, enterotoxigenic Bacteroides fragilis, and colibactin-producing Escherichia coli generate an inflammatory environment and promote tumorigenesis, such as in colorectal cancer, due to the development of the inflammasome and activation of the NF-?B pathway [144]. | positive | What is the relationship between Escherichia coli and colorectal cancer? |
157 | Mycoplasma pneumoniae | HIV-infected | We next examined the cohort for detection of seven of the most common bacterial pulmonary pathogens detected in HIV-infected patients: Pseudomonas aeruginosa, Haemophilus influenzae, Staphylococcus aureus, Chlamydophila pneumoniae, Mycoplasma pneumoniae, Streptococcus pneumoniae and Legionella pneumophila were detected... | relate | What is the relationship between Mycoplasma pneumoniae and HIV-infected? |
158 | AKK | obesity | An HFD markedly decreases AKK in mice, and lower levels of AKK have been shown to be correlated with obesity and insulin resistance in humans25. | negative | What is the relationship between AKK and obesity? |
159 | Lactobacillus acidophilus | mucositis | Taking into account these results, we suggest that a combination of Biffidobacterium longum, Lactobacillus acidophilus, Biffidobacterium breve, Biffidobacterium infantis, and Saccharomyces boulardii could be a good combination of probiotics to reduce incident rates of mucositis or ameliorate its symptoms in chemo or ra... | negative | What is the relationship between Lactobacillus acidophilus and mucositis? |
160 | Roseburia inulinivorans | breast cancer | For example, a decrease in Roseburia inulinivorans may render postmenopausal women more prone to inflammation and therefore at higher risk of breast cancer if the decrease in Roseburia had occurred at the time breast cancer was initiated. | positive | What is the relationship between Roseburia inulinivorans and breast cancer? |
161 | Bacteroides fragilis | inflammatory bowel disease | For example, the colonization of intestinal commensal Bacteroides fragilis protects mice from developing experimental inflammatory bowel disease via TLR2 (Round and Mazmanian, 2010). | negative | What is the relationship between Bacteroides fragilis and inflammatory bowel disease? |
162 | Streptococcus | idiopathic pulmonary fibrosis (IPF) | Similarly, Streptococcus is consistently found in healthy airways but is enriched in COPD [35], idiopathic pulmonary fibrosis (IPF) [36], and pneumonia [37]. | positive | What is the relationship between Streptococcus and idiopathic pulmonary fibrosis (IPF)? |
163 | Lactobacillus | irritable bowel syndrome | One meta?analysis, published in 2017, identified downregulated colonisation of Lactobacillus, Bifidobacterium and Faecalibacterium prausnitzii in patients with irritable bowel syndrome, particularly in irritable bowel syndrome where diarrhoea predominated. | negative | What is the relationship between Lactobacillus and irritable bowel syndrome? |
164 | Enterococcus faecalis | CRC carcinogenesis | Besides Fn, Escherichia coli, Enterococcus faecalis, Streptococcus gallolyticus, and enterotoxigenic Bacteroides fragilis are candidate microorganisms closely associated with CRC carcinogenesis [9]. | relate | What is the relationship between Enterococcus faecalis and CRC carcinogenesis? |
165 | Lactobacillus rhamnosus | myocardial infarction | In addition, Lactobacillus rhamnosus as probiotics demonstrates significant benefits by anti-proliferative and anti-apoptotic effect in cardiomyocytes derived following myocardial infarction and attenuates myocardial hypertrophy and heart failure. | negative | What is the relationship between Lactobacillus rhamnosus and myocardial infarction? |
166 | Fn | colorectal cancer | Several studies demonstrated that the amount of tissue Fn DNA was positively associated with colorectal cancer-specific mortality, which suggested that the enrichment of Fn in CRC tissue might serve as a negative prognostic biomarker12. | positive | What is the relationship between Fn and colorectal cancer? |
167 | Eubacterium desmolans | CRC | The other 10 species including Eubacterium eligens, Coprococcus comes, Eubacterium hadrum, Eubacterium hallII, Fusicatenibacter saccharivorans, Blautia faecis, Roseburia faecis, Ruminococcus lactaris, Eubacterium desmolans, Streptococcus salivarius, decreased in CRC patients (Additional?file?2: Table S1).Fig 2Hierarchi... | negative | What is the relationship between Eubacterium desmolans and CRC? |
168 | Citrobacter freundii | cancer | Through epithelial injury and inflammation, chronic infections (viruses, Helicobacter pylori and other Helicobacter spp., Bacteroides fragilis, Bacteroides vulgatus, Escherichia coli, Citrobacter rodentium, Citrobacter freundii, and protozoa) are linked to carcinogenesis with approximately 18% of the worldwide cancer b... | relate | What is the relationship between Citrobacter freundii and cancer? |
169 | Prevotella | pulmonary diseases | Indeed, mass-DNA sequencing revealed that, besides the well-known lung pathogens, a core microbiota including four persistent anaerobes genera (Veillonella, Streptococcus, Actinomyces and Prevotella) exists and is common to pulmonary diseases (Cheung et al.2013). | relate | What is the relationship between Prevotella and pulmonary diseases? |
170 | AIEC | CD | In particular, adherent-invasive Escherichia coli (AIEC) are enriched in ileal specimens from CD patients, in comparison to non-IBD patients; remarkably, however, AIEC were rarely found in samples from ulcerative colitis (UC) patients (Boudeau et al., 1999; Darfeuille-Michaud et al., 2004; Martinez-Medina et al., 2009)... | relate | What is the relationship between AIEC and CD? |
171 | Streptococcus mutans | vascular disease | Atherosclerosis Fernandes et al.revealed that oral Streptococcus mutans is ubiquitous in the atherosclerotic plaques of patients with vascular disease [230]. | relate | What is the relationship between Streptococcus mutans and vascular disease? |
172 | Ruminococcus | inflammatory bowel disease | The effect of the HMO intervention on eighteen selected genera ? Bifidobacterium, Bacteroides, Barnesiella, Parabacteroides, Prevotella, Alistipes, Lactobacillus, Eubacterium, Blautia, Coprococcus, Dorea, Lachnospiracea incertae sedis, Roseburia, Faecalibacterium, Ruminococcus, Dialister, Escherichia/Shigella and Akker... | relate | What is the relationship between Ruminococcus and inflammatory bowel disease? |
173 | lactobacilli | bacteremia | In a review by Doron and Syndman examining the adverse events associated with probiotics, at least eight cases of bacteremia were associated with lactobacilli, nine cases of sepsis with Saccharomyces boulardii, Lactobacillus rhamnosus GG, Bacillus subtilis, Bifidobacterium breve, or combination probiotics, and two case... | relate | What is the relationship between lactobacilli and bacteremia? |
174 | Bacteroides fragilis | colorectal cancer | Similarly, Enterotoxigenic Bacteroides fragilis and Fusobacterium nucletum are identified to be highly expressed in colorectal cancer tissue compared to the matched tissue, and Fusobacterium nucletum is proved to be associated with high microsatellite instability [24]. | positive | What is the relationship between Bacteroides fragilis and colorectal cancer? |
175 | Faecalibacterium prausnitzii | diarrhea | however, other co-occurring bacteria (such as Faecalibacterium prausnitzii) may also protect against diarrhea, indicating that more studies need to be done to explore the potential protective roles of other microbes in diarrheal diseases. | negative | What is the relationship between Faecalibacterium prausnitzii and diarrhea? |
176 | Tannerella forsythia | GI cancer | Periodontal disease-associated species, Porphyromonas gingivalis, Tannerella forsythia and Prevotella intermedia, were correlated with a risk of GI cancer regardless of cancer type. | relate | What is the relationship between Tannerella forsythia and GI cancer? |
177 | Fusobacterium nucleatum | atherosclerotic plaque lesions | In fact, infection of ApoE null hyperlipidemic mice with four established periodontal pathogens?Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Fusobacterium nucleatum, led to elevations of serum inflammatory markers and progression of atherosclerotic plaque lesions [16]. | positive | What is the relationship between Fusobacterium nucleatum and atherosclerotic plaque lesions? |
178 | Clostridium | colitis | In a mouse model of colitis, a Clostridium strain mediated protective effects via indolepropionate production and consecutive PXR activation [84]. | negative | What is the relationship between Clostridium and colitis? |
179 | Lactobacillus fermentum | inflammatory bowel disease. | For example, Lactobacillus fermentum reduces the levels of proinflammatory cytokines, such as IL-2, IFN-?, IL-4, IL-13, and IL-17A, while increasing levels of anti-inflammatory cytokines, such as IL-10, to relieve symptoms of inflammatory bowel disease. | negative | What is the relationship between Lactobacillus fermentum and inflammatory bowel disease.? |
180 | Faecalibacterium prausnitzii | diarrhea | Some genera are more particularly considered as beneficial for the host like Bifidobacterium, Lactobacillus, Faecalibacterium prausnitzii (a butyrate-producing bacteria), and Akkermansia muciniphila, while others are considered as potentially harmful like Staphylococcus, some species of the Clostridium genus (C.?perfri... | relate | What is the relationship between Faecalibacterium prausnitzii and diarrhea? |
181 | Streptococcus | UC | These results suggested that Odoribacter, Allobaculum and Streptococcus, Lactobacillus, and Lachnospiraceae played vital roles in restoring intestinal flora homeostasis of UC mice through electroacupuncture and moxibustion therapies. | relate | What is the relationship between Streptococcus and UC? |
182 | Streptococcus | cancer | Moreover, Liu HX studied the samples from lung tissues and bronchoscopy and they found that Streptococcus was more abundant in cancer cases whereas Staphylococcus was more abundant in the controls [39]. | positive | What is the relationship between Streptococcus and cancer? |
183 | Lactobacillus acidophilus | alcohol pancreatitis-related liver damage | In another study, a combination treatment using Lactobacillus acidophilus, Lactobacillus helveticus, and Bifidobacterium in rats with alcohol pancreatitis-related liver damage effectively protected against endotoxin/bacterial translocation, as well as liver damage in the course of acute pancreatitis and concomitant hea... | negative | What is the relationship between Lactobacillus acidophilus and alcohol pancreatitis-related liver damage? |
184 | Pseudomonas | GI cancer | Of note, Bilophila, Clostridium, and Pseudomonas are mostly negatively correlated with GI cancer genes, while Haemophilus, Oscillospira, Veillonella, Fusobacterium, and Acidaminococcus are only positively correlated with GI cancer genes (q value <?0.1). | negative | What is the relationship between Pseudomonas and GI cancer? |
185 | Peptoniphilus | HPV-positive cancers | In contrast, Streptococcus anginosus, Peptoniphilus, and Mycoplasma were significantly decreased in HPV-positive cancers. | negative | What is the relationship between Peptoniphilus and HPV-positive cancers? |
186 | Streptococcus salivarius | inflammation | Furthermore, a recent animal experiment demonstrated that INS-GAS mice co-infected with Hp and Streptococcus salivarius developed more severe inflammation, hyperplasia, and dysplasia in the stomach when compared with Hp only at 5 months post-infection. | positive | What is the relationship between Streptococcus salivarius and inflammation? |
187 | Akkermansia muciniphila | obese | The function of these organisms in the gut is unclear, but previous studies have demonstrated that Akkermansia muciniphila is present in low abundance in obese people and is inversely correlated with body weight in rodents and humans [43,44]. | negative | What is the relationship between Akkermansia muciniphila and obese? |
188 | Desulfovibrio | obesity-related metabolic disorders | In addition, the positive influence of DLA-M on HFD-induced gut dysbiosis, especially Blautia and Desulfovibrio, may partially contribute to the attenuation of intestinal and systemic inflammation and the prevention of obesity-related metabolic disorders. | negative | What is the relationship between Desulfovibrio and obesity-related metabolic disorders? |
189 | P. distasonis | RRMS | Similarly, Cekanaviciute et al.reported that Parabacteroides distasonis is at lower abundance in treatment naive RRMS patients from the US west coast than HC, suggesting that higher level of P. distasonis may protect against RRMS (8). | negative | What is the relationship between P. distasonis and RRMS? |
190 | Klebsiella | human IBD | Various studies have suggested that commensal organisms, such as Enterococcus and Klebsiella species, drive the pathogenesis of experimental intestinal inflammation and human IBD. | positive | What is the relationship between Klebsiella and human IBD? |
191 | Streptococcus | COPD | Similarly, Streptococcus is consistently found in healthy airways but is enriched in COPD, idiopathic pulmonary fibrosis (IPF) [36], and pneumonia [37]. | positive | What is the relationship between Streptococcus and COPD? |
192 | Escherichia coli | IBS | MetaMed predicts that another two endogenous microbes, i.e., Bacillus coagulans and Escherichia coli, which exist in the human gut, can treat irritable bowel syndrome (IBS) with a high score of 0.92 and 1.0, respectively. | negative | What is the relationship between Escherichia coli and IBS? |
193 | Clostridium butyricum | mucosal macrophages | In contrast to the induction of regulatory T-cells by probiotics, we recently proposed a distinctive mechanism of probiotic actions, based on findings that a probiotic strain, Clostridium butyricum, which preferentially produces butyrate, suppressed the development of acute experimental colitis in mice by inducing IL-1... | negative | What is the relationship between Clostridium butyricum and mucosal macrophages? |
194 | Lactobacillus rhamnosus | myocardial ischemia | Another study showed similar cardioprotective results in a rat model of myocardial ischemia after supplement with Lactobacillus rhamnosus GR-1 [79]. | negative | What is the relationship between Lactobacillus rhamnosus and myocardial ischemia? |
195 | Akkermansia muciniphila | abdominal migraine | Decreases in Akkermansia muciniphila (P?= .038), Coprococcus catus (P?= .007), Odoribacter splanchnicus (P?=?.050), Clostridium lactatifermentans (P?= .033), and Ruminococcus lactaris (P?= .037) were associated with the presence of abdominal migraine. | relate | What is the relationship between Akkermansia muciniphila and abdominal migraine? |
196 | Streptococcus | CRS | This microbiome dysbiosis theory hypothesized that Staphylococcus aureus, Streptococcus, Pseudomonas, and Anaerobes play key roles as crucial pathogens in CRS. | positive | What is the relationship between Streptococcus and CRS? |
197 | Enterohaemorrhagic Escherichia coli | haemolytic uraemic syndrome | Enterohaemorrhagic Escherichia coli (EHEC) has been reported to be a cause for many illnesses ranging from mild diarrhoea to more severe diseases like haemolytic uraemic syndrome or haemorrhagic colitis (Tarr et?al., 2005). | positive | What is the relationship between Enterohaemorrhagic Escherichia coli and haemolytic uraemic syndrome? |
198 | Enterobacter cloacae | bacteremia | We found one example of an obesity-inducing strain in a human gut opportunistic species, Enterobacter cloacae, which is known to cause bacteremia when translocated into the bloodstream of immune-compromised individuals [42]. | positive | What is the relationship between Enterobacter cloacae and bacteremia? |
199 | EPEC | severe intestinal inflammation | Importantly, EHEC and EPEC can cause severe intestinal inflammation and diarrhea. | positive | What is the relationship between EPEC and severe intestinal inflammation? |
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