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MICROBE
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DISEASE
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EVIDENCE
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RELATION
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QUESTIONS
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Staphylococcus aureus
Psoriasis
Psoriasis skin microbiota is enriched for Staphylococcus aureus and Staphylococcus pettenkoferi We next examined bacterial composition of skin microbial communities from psoriatic and healthy skin at various taxonomic levels.
relate
What is the relationship between Staphylococcus aureus and Psoriasis?
301
Bifidobacterium bifidum
coronary heart disease (CHD)
A recent clinical study by (189), showed that probiotic supplementation (containing L. casei 2 ? 109, Bifidobacterium bifidum 2 ? 109, L. acidophilus 2 ? 109 CFU/day) for a period of 12 weeks had beneficial effects on biomarkers of inflammation in diabetic patients with coronary heart disease (CHD) as well as on glycem...
negative
What is the relationship between Bifidobacterium bifidum and coronary heart disease (CHD)?
302
Escherichia
CD
Faecalibacterium, an unknown genus of Peptostreptococcaceae, Anaerostipes, Methanobrevibacter and an unknown genus of Christensenellaceae were abundant in HC and UC and absent or almost absent in CD ones, while Fusobacterium and Escherichia were abundant in patients with CD and almost absent in HC and UC.
positive
What is the relationship between Escherichia and CD?
303
Prevotella intermedia (Pi)
periodontal diseases
Four common periodontopathogens, Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf), which are highly related to periodontal diseases and were mostly reported in the included studies, were selected for qualitative and quantitative analysis...
relate
What is the relationship between Prevotella intermedia (Pi) and periodontal diseases?
304
Fusobacterium nucleatum
CRC
Applying our approach to a large CRC dataset, we identified that the relative abundance of the enzymatic components of Bifidobacterium, Clostridium, Fusobacterium nucleatum, Porphyromonas gingivalis, and Eubacterium, were significantly higher in the adenoma and CRC patients, as compared to the healthy controls.
positive
What is the relationship between Fusobacterium nucleatum and CRC?
305
Lactobacillus
CRC
The abundance of probiotics such as Bifidobacterium, Lactobacillus, and Ruminococcus were reduced in CRC patients.
negative
What is the relationship between Lactobacillus and CRC?
306
Parabacteroides goldsteinii
obesity-related
In addition, the relative abundance of the obesity-related harmful bacterium, Parabacteroides goldsteinii, and pro-inflammatory Roseburia faecis remained lower in the HESM group than in the HFD and CON groups during weeks 4?20.
positive
What is the relationship between Parabacteroides goldsteinii and obesity-related?
307
Coprococcus catus
obesity
Coprococcus catus, Blautia hydrogenotrophic, Ruminococcus bromii, Ruminococcus obeum, and Eubacterium ventriosum were significantly correlated with obesity in Japanese people [60,61,62], whereas the presence of Bacteroides thetaiotaomicron, Bacteroides faecichinchillae, Flavonifractor plautii, Blautiawexlerae, and Clos...
relate
What is the relationship between Coprococcus catus and obesity?
308
Escherichia coli
tumor development in the colon
Several bacterial populations, including Escherichia coli, Bacteroides fragilis, and Fusobacterium nucleatum, have been shown to directly influence tumor development in the colon.
relate
What is the relationship between Escherichia coli and tumor development in the colon?
309
Enterococcus
urinary tract infection (UTI)
Among the 25 increased genera, many anaerobic bacteria, such as Gardnerella, Prevotella, and Atopobium, are the main pathogens for bacterial vaginosis (BV), while the abundance of many aerobic bacteria, such as Escherichia, Enterococcus, Streptococcus, and Corynebacterium, are closely related to the risk of aerobic vag...
relate
What is the relationship between Enterococcus and urinary tract infection (UTI)?
310
Helicobacter pylori
gastric atrophy
The strongest known risk factor for this devastating disease is infection with Helicobacter pylori, which drives the development of premalignant lesions (such as gastric atrophy, intestinal metaplasia, and dysplasia) that can lead to gastric cancer (Fig 1).
positive
What is the relationship between Helicobacter pylori and gastric atrophy?
311
Akkermansia muciniphila
metabolic diseases
Interestingly, the bacterium Akkermansia muciniphila has been described as a protective ally against the development of metabolic diseases and colitis (22).
negative
What is the relationship between Akkermansia muciniphila and metabolic diseases?
312
Streptococcus
urinary tract infection (UTI)
Among the 25 increased genera, many anaerobic bacteria, such as Gardnerella, Prevotella, and Atopobium, are the main pathogens for bacterial vaginosis (BV), while the abundance of many aerobic bacteria, such as Escherichia, Enterococcus, Streptococcus, and Corynebacterium, are closely related to the risk of aerobic vag...
relate
What is the relationship between Streptococcus and urinary tract infection (UTI)?
313
Akkermansia muciniphila
tumor
Administration of Akkermansia muciniphila, alone or in combination with Enterococcus hirae, restored response to anti-PD1 therapy in melanoma or sarcoma-bearing mice with depleted gut microbiota, as demonstrated by reduced tumor size.
negative
What is the relationship between Akkermansia muciniphila and tumor?
314
Streptococcus
colorectal cancer
The results of faecal sample testing from patients with colorectal cancer (CRC) and healthy individuals have shown that Enterococcus and Streptococcus are increasingly present in samples from CRC patients, while the butyrate-producing bacteria Roseburia and Clostridium predominate in the control samples [16].
positive
What is the relationship between Streptococcus and colorectal cancer?
315
Bifidobacteria
CHB
Specifically, patients with CHB and cirrhosis exhibit dramatically decreased Bifidobacteria and Lactobacillus levels, while Enterococcus and Enterobacteriaceae levels are significantly increased compared to healthy people.
negative
What is the relationship between Bifidobacteria and CHB?
316
Roseburia hominis
IBD
The abundance of butyrate-producing bacteria, such as Roseburia hominis and Faecalibacterium prausnitzii, is decreased in IBD patients (11, 108, 109) and, therefore, fecal SCFAs levels are lower in IBD patients compared to controls (20).
negative
What is the relationship between Roseburia hominis and IBD?
317
Pg
arthritis
In rats, Pg causes signs and symptoms associated with arthritis, whereas heat-killed Pg does not.15 Although periodontal disease induced by Pg infection is thought to be associated with RA pathogenesis, the contribution of fimbriae is largely unknown.
relate
What is the relationship between Pg and arthritis?
318
Lactobacillus casei
hyperglycemia
Yadav et al.showed that a probiotic dahi-supplemented diet, containing Lactobacillus acidophilus and Lactobacillus casei, significantly delayed the onset of glucose intolerance, hyperglycemia, hyperinsulinemia, dyslipidemia, and oxidative stress in high fructose-fed diabetic rats, thus lowering the risk of diabetes and...
negative
What is the relationship between Lactobacillus casei and hyperglycemia?
319
Porphyromonas gingivalis
systemic inflammation
In a rodent study, oral administration of Porphyromonas gingivalis, a periodontal pathogen, induced systemic inflammation and insulin resistance [8].
positive
What is the relationship between Porphyromonas gingivalis and systemic inflammation?
320
Porphyromonas gingivalis
pancreatic
Of all oral bacteria, Porphyromonas gingivalis and Fusobacterium nucleatum might possess the greatest potential to be correlated with oral cancer, as both have been implicated in pancreatic and colorectal cancers.
relate
What is the relationship between Porphyromonas gingivalis and pancreatic?
321
Bacteroides vulgatus
CF
As compared to healthy children, those suffering from CF have reduced abundances of beneficial bacteria like Eubacterium rectale, Bacteroides vulgatus, Bacteroides uniformis, Faecalibacterium prausnitzii, Bifidobacterium catenulatum, and Bifidobacterium adolescentis (Bruzzese et al., 2014).
negative
What is the relationship between Bacteroides vulgatus and CF?
322
Ruminococcus gnavus
CD
The mucolytic bacterium Ruminococcus gnavus, for example, has been previously shown to be increased in the epithelium of UC and CD patients40 and Clostridiaceae are associated with pouch inflammation (37).
positive
What is the relationship between Ruminococcus gnavus and CD?
323
Helicobacter pylori
gastric cancer (GC)
Bacterial Pathogens, Inflammation, and Oncogenesis Helicobacter pylori is perhaps the best described and most known oncogenic bacterial pathogen in relation to gastric cancer (GC) thus classified as a group I carcinogen (Wroblewski et al., 2010).
positive
What is the relationship between Helicobacter pylori and gastric cancer (GC)?
324
Bifidobacterium breve
sepsis
In a review by Doron and Syndman examining the adverse events associated with probiotics, at least eight cases of bacteremia were associated with lactobacilli, nine cases of sepsis with Saccharomyces boulardii, Lactobacillus rhamnosus GG, Bacillus subtilis, Bifidobacterium breve, or combination probiotics, and two case...
positive
What is the relationship between Bifidobacterium breve and sepsis?
325
Prevotella intermedia
Periodontal disease-associated
Periodontal disease-associated species, Porphyromonas gingivalis, Tannerella forsythia and Prevotella intermedia, were correlated with a risk of GI cancer regardless of cancer type.
relate
What is the relationship between Prevotella intermedia and Periodontal disease-associated?
326
Ruminococcus gnavus
CDI
Higher concentration of some species of Firmicutes such as Ruminococcus gnavus, Ruminococcus hansenii, and Clostridium nexile was associated with a greater risk of recurrence and development of CDI.
positive
What is the relationship between Ruminococcus gnavus and CDI?
327
Fn
colorectal adenoma and carcinoma
Collectively, with the detection of Fn, fecal and serum microbiome-based strategies might practical tools for the early diagnosis and treatment of colorectal adenoma and carcinoma.
relate
What is the relationship between Fn and colorectal adenoma and carcinoma?
328
Streptococcus
pneumonia
Similarly, Streptococcus is consistently found in healthy airways but is enriched in COPD, idiopathic pulmonary fibrosis (IPF), and pneumonia.
positive
What is the relationship between Streptococcus and pneumonia?
329
Fusobacterium
tumors from the right colon
For instance, Fusobacterium and Bacteroides fragilis were abundant in tumors from the right colon, whereas Parvimonas micra was associated with tumors from the left colon.
relate
What is the relationship between Fusobacterium and tumors from the right colon?
330
Clostridium histolyticum
autism
Gut microbiota in patients with autism is often different with increased levels of Bacteroides phylum, Sutterella species and toxin-producing Clostridium histolyticum, but with reduced amounts of Firmicutes, Veilonellaseae, Prevotella and Coprococcus species bacteria.
positive
What is the relationship between Clostridium histolyticum and autism?
331
Ruminococcus lactaris
CRC
The other 10 species including Eubacterium eligens, Coprococcus comes, Eubacterium hadrum, Eubacterium hallII, Fusicatenibacter saccharivorans, Blautia faecis, Roseburia faecis, Ruminococcus lactaris, Eubacterium desmolans, Streptococcus salivarius, decreased in CRC patients (Additional?file?2: Table S1).Fig 2Hierarchi...
negative
What is the relationship between Ruminococcus lactaris and CRC?
332
Mycoplasma
HPV-positive cancers
In contrast, Streptococcus anginosus, Peptoniphilus, and Mycoplasma were significantly decreased in HPV-positive cancers.
negative
What is the relationship between Mycoplasma and HPV-positive cancers?
333
Porphyromonas endodontalis
periodontitis
In periodontitis patients, four genera (Dysgonomonas, Paenibacillus, Mycoplasma, and Campylobacter) and five species (Porphyromonas endodontalis, Dysgonomonas wimpennyi, P. canis, Campylobacter gracilis, and Leptotrichia buccalis) were higher, and only one species (P. melaninogenica) was lower in the C+P+ group compare...
positive
What is the relationship between Porphyromonas endodontalis and periodontitis?
334
Faecalibacterium prausnitzii
Crohn\'s disease (CD)
A decrease in Faecalibacterium prausnitzii as a result of AB treatment is important because this bacterium exhibits anti-inflammatory capacity and a reduction in the amount of this bacterium was shown to be associated with inflammatory diseases such as Crohn\'s disease (CD) or ulcerative colitis (UC) [2]?[27].
negative
What is the relationship between Faecalibacterium prausnitzii and Crohn\'s disease (CD)?
335
Parabacteroides
adenoma
For example, microbes such as Dorealongicatena and Parabacteroides, whose abundance was generally low or even non-existent in the healthy samples, was high in patients with adenoma and colorectal cancer.
negative
What is the relationship between Parabacteroides and adenoma?
336
Parabacteroides
colorectal cancer
For example, microbes such as Dorealongicatena and Parabacteroides, whose abundance was generally low or even non-existent in the healthy samples, was high in patients with adenoma and colorectal cancer.
negative
What is the relationship between Parabacteroides and colorectal cancer?
337
Clostridium
attenuate colitis
Bacteria belonging to Clostridium clusters XIVa, XVIII and IV, which lack virulence factors and prominent toxins, were found to modulate host fatty acid metabolism, induce Treg cell activity and attenuate colitis [38].
negative
What is the relationship between Clostridium and attenuate colitis?
338
Clostridium
ASD
We also observed that Clostridium clostridioforme, affiliated to Clostridium genera, was higher in the ASD group than in healthy children.
positive
What is the relationship between Clostridium and ASD?
339
Lachnospiraceae
colon cancer
The culture-independent sequencing of the 16S region revealed a number of changes at the family and genus level when compared to cellulose, including the stimulation of Parabacteroides, Dialister and Lachnospiraceae populations, each of which have been shown to be reduced in IBD-associated dysbiosis, with Lachnospirace...
negative
What is the relationship between Lachnospiraceae and colon cancer?
340
Escherichia
IBS
Interestingly, Proteobacteria (Shigella/Escherichia) was among the top five dysbiosis?contributing bacterial groups for both IBS and IBD, implying similarities in dysbiosis between IBS and IBD.
relate
What is the relationship between Escherichia and IBS?
341
Helicobacter pylori
gastric
For example, the gastric pathogen Helicobacter pylori stimulates expression of PAI and of uPA and its receptor (uPAR) in gastric epithelial cells 13 and can also affect epithelial signaling pathways partially through activation of EGFR.
relate
What is the relationship between Helicobacter pylori and gastric?
342
Peptostreptococcus
periodontitis
Additionally, our data in UC and CC specimens show the presence of several orange (Prevotella, Peptostreptococcus, Eubacterium, Fusobacterium, and Campylobacter), red (Porphyromonas), purple (Veillonella), and yellow (Streptococcus) complex putative oral pathogens known to cause gingivitis and periodontitis among IBD p...
relate
What is the relationship between Peptostreptococcus and periodontitis?
343
Bacillus cereus
dysbiosis
For example, intervention with a probiotic mix containing Bifidobacterium infantis, Lactobacillus acidophilus, and Bacillus cereus was capable of counteracting HFD-induced dysbiosis and related gut-liver axis activation along with the improvement of liver histology and inflammation.
negative
What is the relationship between Bacillus cereus and dysbiosis?
344
Fusobacterium
tumor
In this study, an inverse relationship in the abundance of Fusobacterium and Streptococcus species was observed in the tumor tissues versus normal controls (Fig?3).
relate
What is the relationship between Fusobacterium and tumor?
345
Clostridium difficile
severe gastrointestinal infections
The high abundance of Bifidobacterium species in infants is considered to promote the maturation of the healthy immune system, while high presence of Clostridium difficile is considered as one of the major intra-hospital hazards of severe gastrointestinal infections during infancy [55].
relate
What is the relationship between Clostridium difficile and severe gastrointestinal infections?
346
Fusobacterium vincentii
CRC-related
For example, Zeller and Feng et al.showed that Porphyromonas asaccharolytica, Peptostreptococcus stomatis, Fusobacterium vincentii, and Fusobacterium animalis were predictive in the early diagnosis of colorectal cancer, which are among the tops of our list; in particular, F. nucleatum is a common CRC-related species wh...
relate
What is the relationship between Fusobacterium vincentii and CRC-related?
347
Ruminococcus
Crohn?s disease
For example, 2 of the microorganisms on our panel, Escherichia-Shigella and Ruminococcus, are associated with Crohn?s disease, while 5 other organisms, Akkermansia muciniphila, Bifidobacterium, Dialister invisus, Odoribacter and Roseburia, are inversely associated with Crohn?s disease (Fig 5, S2 Table).
relate
What is the relationship between Ruminococcus and Crohn?s disease?
348
Staphylococcus aureus
atopic dermatitis
It has been well documented that the skin of patients with atopic dermatitis (AD) is more prone to the colonization and overgrowth of Staphylococcus aureus (S. aureus) [6].
positive
What is the relationship between Staphylococcus aureus and atopic dermatitis?
349
Fusobacterium varium
UC
Moreover, Fusobacterium varium isolated from UC patients could kill Vero cells, and its culture supernatants caused UC-like lesions in mice [33].Various Streptococcus mutants with a high detection rate in UC patients were also confirmed to aggravate the colitis [34].
positive
What is the relationship between Fusobacterium varium and UC?
350
Lactobacillus rhamnosus
UC
Previous studies have shown that Lactobacillus bulgaricus can reduce colitis, and Lactobacillus rhamnosus can effectively maintain UC remission[16].
negative
What is the relationship between Lactobacillus rhamnosus and UC?
351
Acinetobacter
IBD
The genera Acinetobacter and Bacteroides are increased significantly in IBD patients during the active phase (Andoh et al., 2012; Tang et al., 2015), though a massive amount of Dialister invisus has been identified in the state of inactivity or dormancy in the gut of patients with IBD (Schirmer et al., 2018).
positive
What is the relationship between Acinetobacter and IBD?
352
ETEC
diarrhea
Our data also suggest there is a specific, preexisting microbial balance that predisposes or protects against ETEC induced diarrhea.
positive
What is the relationship between ETEC and diarrhea?
353
Fusobacterium
sAH
For these genera, the abundance of Haemophilus, Sutterella, Campylobacter, Lactobacillus, Faecalibacterium, Prevotella, Paraprevotella and Fusobacterium was higher in sAH patients and that of Serratia, Acinetobacter, Pseudomonas and Enterococcus was higher in CAP patients.
positive
What is the relationship between Fusobacterium and sAH?
354
Prevotella pallens
gastric cancer
Moreover, apart from H. Pylori, reduction of different other bacteria like Streptococcus sinensis, Acinetobacter baumannii, Prevotella pallens, Klebsiella pneumonia, Lactobacillus colihominis, and Lachnospiraceae are also responsible for gastric cancer in the human [91][92][93].
relate
What is the relationship between Prevotella pallens and gastric cancer?
355
Veillonella
IBS
For instance, it is known that abundance of the genus Veillonella is positively associated with IBS, while the relative abundances of genera Alistipes, Bifidobacterium, and Lactobacillus and the species Collinsella aerofaciens are inversely associated with IBS.
positive
What is the relationship between Veillonella and IBS?
356
Fusobacterium nucleatum
periodontal disease
Oral Fusobacterium consists mainly of the species Fusobacterium nucleatum (F. nucleatum), an adherent[12], invasive[13], and proinflammatory[14,15] bacterium that is linked to periodontal disease[16].
relate
What is the relationship between Fusobacterium nucleatum and periodontal disease?
357
Blautia faecis
CRC
The other 10 species including Eubacterium eligens, Coprococcus comes, Eubacterium hadrum, Eubacterium hallII, Fusicatenibacter saccharivorans, Blautia faecis, Roseburia faecis, Ruminococcus lactaris, Eubacterium desmolans, Streptococcus salivarius, decreased in CRC patients (Additional?file?2: Table S1).Fig 2Hierarchi...
negative
What is the relationship between Blautia faecis and CRC?
358
Faecalibacterium prausnitzii
irritable bowel syndrome
One meta?analysis, published in 2017, identified downregulated colonisation of Lactobacillus, Bifidobacterium and Faecalibacterium prausnitzii in patients with irritable bowel syndrome, particularly in irritable bowel syndrome where diarrhoea predominated.
negative
What is the relationship between Faecalibacterium prausnitzii and irritable bowel syndrome?
359
Ruminococcus
UC
Moayyedi et al.did not pretreat UC patients with antibiotics prior to FMT and found that the bacterial family Lachnospiraceae and the genus Ruminococcus were associated with their donor that successfully induced remission (44), indicating that UC patients can be innately primed to accept beneficial bacteria unlike heal...
relate
What is the relationship between Ruminococcus and UC?
360
Filifactor alocis
periodontitis
Previous research showed that species including Parvimonas micra, C. gracilis, Treponema socranskii, Dialister pneumosintes, Streptococcus sanguinis, and T. forsythia were significantly elevated in smoking periodontitis patients than they were in non-smoking periodontitis patients, and species including F. nucleatum an...
positive
What is the relationship between Filifactor alocis and periodontitis?
361
Streptococcus anginosus
UUI
Also, Actinobaculum schaalii, Actinomyces neuii, Aerococcus urinae, Arthrobacter cumminsii, Corynebacterium coyleae, Gardnerella vaginalis, Oligella urethralis, and Streptococcus anginosus were more frequently isolated from UUI women (see Table?S2 in the supplemental material).
relate
What is the relationship between Streptococcus anginosus and UUI?
362
Roseburia faecis
CRC
The other 10 species including Eubacterium eligens, Coprococcus comes, Eubacterium hadrum, Eubacterium hallII, Fusicatenibacter saccharivorans, Blautia faecis, Roseburia faecis, Ruminococcus lactaris, Eubacterium desmolans, Streptococcus salivarius, decreased in CRC patients (Additional?file?2: Table S1).Fig 2Hierarchi...
negative
What is the relationship between Roseburia faecis and CRC?
363
Blautia hydrogenotrophic
obesity
Coprococcus catus, Blautia hydrogenotrophic, Ruminococcus bromii, Ruminococcus obeum, and Eubacterium ventriosum were significantly correlated with obesity in Japanese people [60,61,62], whereas the presence of Bacteroides thetaiotaomicron, Bacteroides faecichinchillae, Flavonifractor plautii, Blautiawexlerae, and Clos...
relate
What is the relationship between Blautia hydrogenotrophic and obesity?
364
Clostridium immunis
colitis
Similarly, Surana and Kasper showed that Clostridium immunis, a single Lachnospiraceae isolate from the feces of mice colonized with human gut microbiota, conferred protection against experimentally induced colitis, which is consistent with the clinical observation of an inverse relationship between Lachnospiraceae abu...
negative
What is the relationship between Clostridium immunis and colitis?
365
Fusobacterium nucleatum
colon cancer
She elaborated that several bacteria are associated with chronic inflammation and a subsequent increased risk of lung and colon cancer, including Mycobacterium tuberculosis (lung cancer) and Fusobacterium nucleatum (colon cancer), a bacterium commonly isolated from inflammatory bowel disease patients and a risk factor ...
positive
What is the relationship between Fusobacterium nucleatum and colon cancer?
366
Burkholderia cepacia
CF lung
Although Pseudomonas aeruginosa is the major colonizer of the CF lung, Burkholderia cepacia complex and Staphylococcus aureus also predominate in these infections, with colonization of B.?cepacia indicating chronic infection (Jones et al., 2004).
relate
What is the relationship between Burkholderia cepacia and CF lung?
367
Bifidobacterium
Crohn?s disease
For example, 2 of the microorganisms on our panel, Escherichia-Shigella and Ruminococcus, are associated with Crohn?s disease, while 5 other organisms, Akkermansia muciniphila, Bifidobacterium, Dialister invisus, Odoribacter and Roseburia, are inversely associated with Crohn?s disease (Fig 5, S2 Table).
negative
What is the relationship between Bifidobacterium and Crohn?s disease?
368
Faecalibacterium prausnitzii
esophageal dysmotility
Andr?asson et al.used a genome-based microbiota test of stool samples to study the gut flora composition of 98 SSc patients [35] and found that 75.5% had dysbiosis (low levels of Faecalibacterium prausnitzii and/or Clostridiaceae) and that this was significantly associated with esophageal dysmotility, micronutrient def...
relate
What is the relationship between Faecalibacterium prausnitzii and esophageal dysmotility?
369
Escherichia
intestinal inflammation
Increase of Escherichia/Shigella can induce intestinal inflammation, causing intestinal barrier dysfunction.
positive
What is the relationship between Escherichia and intestinal inflammation?
370
Lactobacillus rhamnosus GG
GDM
For example, consumption of the probiotics Lactobacillus rhamnosus GG and Bifidobacterium lactis BB12 from T1 of pregnancy in a double-blind, placebo-controlled study significantly reduced the incidence of GDM (P = 0.003) [37].
negative
What is the relationship between Lactobacillus rhamnosus GG and GDM?
371
Moraxella
pneumonia
Nasal microbiota compositions characterized by Moraxella, Streptococcus, or Haemophilus have been reported to be associated with upper respiratory infection (URI) asthma, AOM, pneumonia, or bronchiolitis.
relate
What is the relationship between Moraxella and pneumonia?
372
Enterococcus hirae
diarrhea
In general, enterococci are not regarded as pathogenic in mink, but Enterococcus hirae has been associated with diarrhea in 4?7?week old mink kits submitted for diagnostic testing (Chri?l, pers.
relate
What is the relationship between Enterococcus hirae and diarrhea?
373
Lactobacillus mucosae
breast cancer
Other lactobacilli have also been implicated in the metabolism of other PGs, e.g., the in vitro conversion of the isoflavonic daidzin, present in soy products, by the pig intestinal commensal Lactobacillus mucosae EPI2, to the estrogen-mimicking aglycone equol, which has been proposed to be protective against breast ca...
negative
What is the relationship between Lactobacillus mucosae and breast cancer?
374
Tannerella forsythia
COPD
In a previous study, some specific bacteria including Klebsiella pneumonia, Pseudomonas aeruginosa, Streptococcus pneumoniae, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia were more abundant in both tracheal aspirate and periodontal pockets in severe acute exacerbations of COPD patients, sugge...
positive
What is the relationship between Tannerella forsythia and COPD?
375
Helicobacter pylori
tumor
Intestinal bacteria with pro-carcinogenic properties, such as Helicobacter pylori, Escherichia coli, Streptococcus gallolyticus (formerly bovis), Fusobacterium spp., and Bacteroides fragiles have been identified in fecal or tumor samples from human patients with adenoma and carcinoma [11?15].
positive
What is the relationship between Helicobacter pylori and tumor?
376
Treponema socranskii
periodontal disease
In addition, microbes associated with periodontal disease, including Treponema socranskii, T. amylovorum, Veillonella dispar, Aggregatibacter segnis, and Bacteroides eggerthii were identified.
relate
What is the relationship between Treponema socranskii and periodontal disease?
377
Enterococcus
bacterial endocarditis
Important clinical infections caused by Enterococcus include urinary tract infections, bacteremia, bacterial endocarditis, diverticulitis, and meningitis.
positive
What is the relationship between Enterococcus and bacterial endocarditis?
378
Parabacteroides
osteoporosis
In addition, Parabacteroides and Lactobacillus were more abundant in the osteoporosis group than in the control group (Supplementary Figure 4), and the relative abundances of Bacteroides massiliensis, Lachnospira pectinoschiza, Bacteroides coprocola and Blautia were significantly higher in the control group than in the...
positive
What is the relationship between Parabacteroides and osteoporosis?
379
Enterobacteriaceae
DD
Recently, lower amounts of Enterobacteriaceae were found in the colon mucosa of DD patients compared with healthy controls[17], whereas higher amounts of Akkermansia and no difference in the Escherichia coli subgroup were found in feces in another DD cohort[18].
negative
What is the relationship between Enterobacteriaceae and DD?
380
Escherichia
brain abscess
Pseudomonas and Escherichia have been reported in brain abscess related to surgical procedure and paranasal sinus infection [22].
relate
What is the relationship between Escherichia and brain abscess?
381
Lactobacillus plantarum
alcoholic hepatitis
[23] demonstrated that, after 5 days of treatment with Bifidobacterium bifidum and Lactobacillus plantarum 8PA3, mild alcoholic hepatitis patients had a significant end-of-treatment reduction of ALT and AST, lactate dehydrogenase, and total bilirubin.
negative
What is the relationship between Lactobacillus plantarum and alcoholic hepatitis?
382
Alistipes finegoldii
colitis
Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii enhance and Alistipes finegoldii attenuates colitis in mice
negative
What is the relationship between Alistipes finegoldii and colitis?
383
Clostridium
gastric cancer
Our results showed an underrepresentation of H. pylori among the gastric microbiota of the patients with gastric cancer, while Fusobacterium and Clostridium were frequently enriched.
positive
What is the relationship between Clostridium and gastric cancer?
384
Escherichia
aerobic vaginitis (AV)
Among the 25 increased genera, many anaerobic bacteria, such as Gardnerella, Prevotella, and Atopobium, are the main pathogens for bacterial vaginosis (BV), while the abundance of many aerobic bacteria, such as Escherichia, Enterococcus, Streptococcus, and Corynebacterium, are closely related to the risk of aerobic vag...
relate
What is the relationship between Escherichia and aerobic vaginitis (AV)?
385
Fusobacterium
chronic inflammatory
Chronic Inflammatory Process Oral bacteria, especially anaerobic species such as Porphyromonas, Prevotella, and Fusobacterium, are responsible for periodontal diseases and lead to chronic inflammatory processes.
positive
What is the relationship between Fusobacterium and chronic inflammatory?
386
Bacteroides fragilis
Parkinson's Disease
A 2-year follow-up study by the same group recently revealed that lower counts of Bifidobacterium and Bacteroides fragilis in year 0 were associated with worsening on the Unified Parkinson's Disease Rating Scale over the next 2 years, suggesting that changes in the intestinal microbiota are associated with the progress...
relate
What is the relationship between Bacteroides fragilis and Parkinson's Disease ?
387
Enterococcus
urinary tract infections
Important clinical infections caused by Enterococcus include urinary tract infections, bacteremia, bacterial endocarditis, diverticulitis, and meningitis.
positive
What is the relationship between Enterococcus and urinary tract infections?
388
Ruminococcus
CD
In particular, taxa higher in disease include Blautia and Intestinibacter in CD, Bifidobacterium in UC, and unclassified Clostridiales incertae sedis XIII and Erysipelotrichaceae in MS. Asaccharobacter, Clostridium IV, Coprococcus, Ruminococcus (Lachnospiraceae), and Oscillibacter were lower in CD, Dialister was lower ...
negative
What is the relationship between Ruminococcus and CD?
389
Porphyromonas gingivalis
cancerogenic
Fusobacterium nucleatum and Porphyromonas gingivalis are identified as cancerogenic bacteria.
positive
What is the relationship between Porphyromonas gingivalis and cancerogenic?
390
Campylobacter concisus
gastritis
To test whether Campylobacter concisus existed in the stomach, we detected the Campylobacter concisus in tongue coating and gastric fluid in a validation cohort of 38 gastritis patients by quantitative polymerase chain reaction (qPCR).
relate
What is the relationship between Campylobacter concisus and gastritis?
391
Escherichia coli
intra-abdominal infections
The causative pathogens and foci included the following: 3 episodes of Staphylococcus aureus surgical site infections, 3 episodes of Enterococcus faecium cholangitis, 2 episodes of intra-abdominal infections caused by Escherichia coli, an intra-abdominal abscess caused by E. faecium, a ventilator-associated pneumonia c...
positive
What is the relationship between Escherichia coli and intra-abdominal infections?
392
Streptococcus
overweight
Oral intervention with a probiotic mixture, containing three Bifidobacterium strains, four Lactobacillus strains and one Streptococcus strain, was also associated with reduced BMI in overweight children.
relate
What is the relationship between Streptococcus and overweight?
393
Veillonella
PPD
The genera identified as Capnocytophaga, Corynebacterium (C. durum), Fusobacterium (mainly F. nucleatum), Gemella, Haemophilus, Leptotrichia, Streptococcus, and Veillonella (especially in NS-Control and NS-Perio groups) were significantly negatively correlated with PPD, CAL, and/or BOP.
negative
What is the relationship between Veillonella and PPD?
394
Escherichia coli
eczema
In the Lifestyle and Genetic Constitution (KOALA) Birth Cohort Study ? an extensive epidemiological study with involved 957 infants from Netherlands aged 1?month ? the presence of Escherichia coli and Clostridium difficile in stools has been associated with a higher risk to develop eczema [14].
positive
What is the relationship between Escherichia coli and eczema?
395
Bifidobacteria
HIV-infected
In HIV-infected patients, inflammatory markers were concurrent with an altered fecal microbiome composition featuring increased abundances of Pseudomonas aeruginosa and Candida albicans and decreased abundances of Lactobacilli and Bifidobacteria (Gori et al., 2008).
positive
What is the relationship between Bifidobacteria and HIV-infected?
396
Streptococcus gallolyticus
colorectal cancer
Fusobacterium nucleatum, Escherichia coli, Enterococcus faecalis, Streptococcus gallolyticus, and enterotoxigenic Bacteroides fragilis are candidate microorganisms that were pointed out as initial triggers in the development of colorectal cancer (CRC).
positive
What is the relationship between Streptococcus gallolyticus and colorectal cancer?
397
Escherichia coli
bacteraemia
Interestingly, Escherichia coli and Enterococcus faecium could be inferred, on the basis of relationship patterns, to be harmful, in line with previous studies, which concluded that they may cause or underlie bacteraemia and intra-abdominal infections23,24.
positive
What is the relationship between Escherichia coli and bacteraemia?
398
Aggregatibacter actinomycetemcomitans (Aa)
periodontal diseases
Four common periodontopathogens, Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf), which are highly related to periodontal diseases and were mostly reported in the included studies, were selected for qualitative and quantitative analysis...
relate
What is the relationship between Aggregatibacter actinomycetemcomitans (Aa) and periodontal diseases?
399
Escherichia Coli
tumour
Enterotoxic strains of Bacteroides fragilis, PKS+ve strains of Escherichia Coli, Fusobacterium nucleatum, Enterococcus faecalis and Streptococcus gallolyticus are candidate tumour-associated microbial species considered here for their roles in disease causality.
relate
What is the relationship between Escherichia Coli and tumour?