Unnamed: 0 int64 0 1.1k | MICROBE stringlengths 2 45 | DISEASE stringlengths 2 53 | EVIDENCE stringlengths 58 610 | RELATION stringclasses 4
values | QUESTIONS stringlengths 44 112 |
|---|---|---|---|---|---|
800 | Clostridium butyricum | ulcerative colitis | These include Clostridium butyricum MIYAIRI 588 (Clostridium cluster I), demonstrated as safe in vitro and in rodents (26) and moderately effective in treating Helicobacter pylori infections (27), antibiotic-associated diarrhea (28), and preventing formation of postsurgery pouchitis in ulcerative colitis patients (29),... | negative | What is the relationship between Clostridium butyricum and ulcerative colitis? |
801 | Fusobacterium | colorectal cancer | In colorectal cancer, Fusobacterium has been reported to promote therapy resistance [22]. | negative | What is the relationship between Fusobacterium and colorectal cancer? |
802 | Klebsiella pneumoniae | liver abscess | Another pathogenic bacteria, Klebsiella pneumoniae (belonging to the bacterial family Enterobacteriaceae), associated with a wide range of infections, including cystitis, pyelonephritis, osteomyelitis, meningitis, bacteremia, septicemia, liver abscess, and wound infections [41,42,43] has been identified in our study. | relate | What is the relationship between Klebsiella pneumoniae and liver abscess? |
803 | Bacteroides fragilis | colitis | [12] indicated that antibody-mediated blockade of IL-17 and the receptor for IL-23, a key cytokine that amplifies T-helper 17 cell responses, inhibits enterotoxigenic Bacteroides fragilis?induced colitis, colonic hyperplasia, and tumor formation. | positive | What is the relationship between Bacteroides fragilis and colitis? |
804 | Bacteroides fragilis | colon tumors | For instance, cefoxitin treatment resulted in complete clearance of enterotoxigenic Bacteroides fragilis, a microbe that causes IL17A-dependent colon tumors. | positive | What is the relationship between Bacteroides fragilis and colon tumors? |
805 | Fusobacterium nucleatum | periodontal inflammation | The other species associated with periodontal inflammation, Prevotella intermedia, Fusobacterium nucleatum, and Parvimonas micra are a part of the ?orange? complex. | relate | What is the relationship between Fusobacterium nucleatum and periodontal inflammation? |
806 | Prevotella | IBD | Patients with IBD have an expansion of pro-inflammatory bacteria such as Prevotella, R. gnavus, and Veillonella. | positive | What is the relationship between Prevotella and IBD ? |
807 | Lactobacillus fermentum | psychological abnormalities | Interestingly, the administration of probiotics (Lactobacillus fermentum strain NS9) reverses the physiological and psychological abnormalities induced by ampicillin in rats . | negative | What is the relationship between Lactobacillus fermentum and psychological abnormalities? |
808 | Streptococcus | aerobic vaginitis (AV) | Among the 25 increased genera, many anaerobic bacteria, such as Gardnerella, Prevotella, and Atopobium, are the main pathogens for bacterial vaginosis (BV), while the abundance of many aerobic bacteria, such as Escherichia, Enterococcus, Streptococcus, and Corynebacterium, are closely related to the risk of aerobic vag... | relate | What is the relationship between Streptococcus and aerobic vaginitis (AV)? |
809 | Lactobacillus salivarius | mastitis | The published paper describes the results at day 21, and concludes that women receiving Lactobacillus fermentum or Lactobacillus salivarius had less pain and risk of recurrence of mastitis than women in the antibiotic arm of the trial. | negative | What is the relationship between Lactobacillus salivarius and mastitis? |
810 | R. gnavus | CD | For example, R. gnavus was higher, but Ruminococcus obeum was lower in CD. | positive | What is the relationship between R. gnavus and CD? |
811 | Clostridiales | IBS | The present study also shows that individual psychiatric diseases, viz., depression and PTSD, have unique intestinal flora profiles and that dysbiosis, such as decreases in Clostridiales species, accompanying the onset of depression could promote the development of IBS. | relate | What is the relationship between Clostridiales and IBS? |
812 | Collinsella aerofaciens | obese | For example, the Collinsella aerofaciens were abundant among the obese BMI and within processed food category equating in both groups to a total of 6.5% of the gut microbiota population of the individuals in the group. | relate | What is the relationship between Collinsella aerofaciens and obese? |
813 | Akkermansia muciniphila | colorectal cancer | Finally, the murB gene, a specific marker for the presence of Akkermansia muciniphila, was also included in this study because of reports linking this species to colorectal cancer (Weir et al., 2013). | relate | What is the relationship between Akkermansia muciniphila and colorectal cancer? |
814 | Escherichia coli | CD | Enterobacteria are particularly elevated in patients with CD and UC, especially Escherichia coli, which has been isolated from the ileus of individuals with CD through biopsies in several studies [63]. | positive | What is the relationship between Escherichia coli and CD? |
815 | Ruminococcus gnavus | inflammatory bowel disease | Another potential target of interest could be Ruminococcus gnavus which belongs to the Lachnospiraceae family and has been linked to inflammatory bowel disease (Joossens et al., 2011; Hall et al., 2017; Henke et al., 2019). | relate | What is the relationship between Ruminococcus gnavus and inflammatory bowel disease? |
816 | Haemophilus influenzae | bronchiectasis | Nontypeable Haemophilus influenzae (NTHi) is the most common bacterium found in patients with bronchiectasis. | relate | What is the relationship between Haemophilus influenzae and bronchiectasis? |
817 | Enterococcus | experimental intestinal inflammation | Various studies have suggested that commensal organisms, such as Enterococcus and Klebsiella species, drive the pathogenesis of experimental intestinal inflammation and human IBD. | positive | What is the relationship between Enterococcus and experimental intestinal inflammation? |
818 | EHEC | neutrophilic inflammation | In our model, Stx-negative EHEC is still capable of mounting a strong neutrophilic inflammation, which supports these data. | positive | What is the relationship between EHEC and neutrophilic inflammation? |
819 | Moraxella | upper respiratory infection | Nasal microbiota compositions characterized by Moraxella, Streptococcus, or Haemophilus have been reported to be associated with upper respiratory infection (URI) [12] asthma [13], AOM [12], pneumonia, or bronchiolitis [14, 15]. | relate | What is the relationship between Moraxella and upper respiratory infection? |
820 | Streptococcus pneumoniae | IPF | Specifically, the authors observed pathogen growth (e.g., Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae, Moraxella catarrhalis, Pseudomonas aeruginosa and Proteus mirabilis) in 8/22 (36%) IPF patients, suggesting that occult bacterial infection may contribute to the development of IPF. | positive | What is the relationship between Streptococcus pneumoniae and IPF? |
821 | Prevotella melaninogenica | hypoxemia | However, Prevotella melaninogenica was more consistently present among patients with hypoxemia, resulting in its higher ranking over Staphylococcus spp. | relate | What is the relationship between Prevotella melaninogenica and hypoxemia? |
822 | Parvimonas | colorectal cancer | Several species of Peptostreptococcus and Parvimonas were extensively enriched in cancer samples, including Peptostreptococcus stomatis and Parvimonas micra, both of which are reportedly related to colorectal cancer. | relate | What is the relationship between Parvimonas and colorectal cancer? |
823 | Bifidobacterium longum | endotoxaemia | The second study showed that long-term synbiotic supplementation (Bifidobacterium longum and FOS) in sixty-six overweight non-alcoholic steatohepatitis patients could reduce endotoxaemia, insulin resistance, steatosis and several metabolic and inflammatory parameters( 101 ). | negative | What is the relationship between Bifidobacterium longum and endotoxaemia? |
824 | Fn | tonsillitis | [4] Using real-time PCR to study tonsillitis patients aged 18 to 32 years and healthy controls in Denmark, Jensen and colleagues found that 48% of 105 nonstreptococcal tonsillitis patients were positive for Fn compared to 21% of controls, suggesting that this organism may be a major cause of bacterial pharyngitis. | positive | What is the relationship between Fn and tonsillitis? |
825 | Streptococcus | meningitis | Streptococcus suis (S. suis) is a major swine pathogen that causes various diseases such as meningitis, septicemia, and endocarditis, which result in large economic losses in the pig industry. | positive | What is the relationship between Streptococcus and meningitis? |
826 | Streptococcus | pneumonia illness | It is known that early colonisation dominated by S. pneumoniae is a risk factor for pneumonia illness later in childhood, however in this population pneumococcal colonisation rates are high and there are not enough infants to determine whether being in the Streptococcus I dominated clusters in early life leads to a gre... | positive | What is the relationship between Streptococcus and pneumonia illness? |
827 | Bilophila | GI cancer | Of note, Bilophila, Clostridium, and Pseudomonas are mostly negatively correlated with GI cancer genes, while Haemophilus, Oscillospira, Veillonella, Fusobacterium, and Acidaminococcus are only positively correlated with GI cancer genes (q value <?0.1). | negative | What is the relationship between Bilophila and GI cancer? |
828 | Fusicatenibacter saccharivorans | CRC | The other 10 species including Eubacterium eligens, Coprococcus comes, Eubacterium hadrum, Eubacterium hallII, Fusicatenibacter saccharivorans, Blautia faecis, Roseburia faecis, Ruminococcus lactaris, Eubacterium desmolans, Streptococcus salivarius, decreased in CRC patients (Additional?file?2: Table S1).Fig 2Hierarchi... | negative | What is the relationship between Fusicatenibacter saccharivorans and CRC? |
829 | Faecalibacterium prausnitzii | Crohn?s disease | Moreover, another study revealed the importance of anti-inflammatory bacteria such as Faecalibacterium prausnitzii, whose levels are low in patients with Crohn?s disease (CD). | negative | What is the relationship between Faecalibacterium prausnitzii and Crohn?s disease? |
830 | Campylobacter | CRC | Simultaneously, various opportunistic pathogens, able to induce inflammatory or metabolic disorders, including Campylobacter, Enterococcaceae, Erysipelotrichaceae, and Fusobacterium are increased in CRC patients [49]. | positive | What is the relationship between Campylobacter and CRC? |
831 | Lactobacillus brevis | mucositis | Head and neck cancer patients who were administered radiation and chemotherapy treatment and received Lactobacillus brevis oral-treatments with CD2 lozenges had a lower incidence of mucositis and greater treatment completion. | negative | What is the relationship between Lactobacillus brevis and mucositis? |
832 | Bacteroides | HCC | The sequencing of 16S bacterial RNA showed in the stool of HCC patients increased abundance of Bacteroides, Ruminococcus, Enterococcus, Phascolarctobacterium, and Oscillospira and decreased abundance of Bifidobacteria and Blautia as compared with liver cirrhosis without HCC. | positive | What is the relationship between Bacteroides and HCC? |
833 | Corynebacterium | OM | Studies by Pettigrew and coworkers have, similarly, shown that Corynebacterium and Dolosigranulum are protective for development of OM, and that Actinomyces, Rothia, Neisseria, and Veillonella are associated with an increased risk for development of AOM [48??]. | negative | What is the relationship between Corynebacterium and OM? |
834 | Lactobacillus | IBS | For instance, it is known that abundance of the genus Veillonella is positively associated with IBS, while the relative abundances of genera Alistipes, Bifidobacterium, and Lactobacillus and the species Collinsella aerofaciens are inversely associated with IBS. | negative | What is the relationship between Lactobacillus and IBS? |
835 | Fusobacterium nucleatum | OSCC | [34] reported that chronic infection of Porphyromonas gingivalis and Fusobacterium nucleatum promotes chemically induced OSCC in mice. | positive | What is the relationship between Fusobacterium nucleatum and OSCC? |
836 | Escherichia coli | tumor | Intestinal bacteria with pro-carcinogenic properties, such as Helicobacter pylori, Escherichia coli, Streptococcus gallolyticus (formerly bovis), Fusobacterium spp., and Bacteroides fragiles have been identified in fecal or tumor samples from human patients with adenoma and carcinoma [11?15]. | positive | What is the relationship between Escherichia coli and tumor? |
837 | Bacteroides fragilis | CD | Two CD patients (labeled #10 and 11 in Figure 1) showed strong increases in the relative abundances of Bacteroides fragilis during active disease, i.e. | positive | What is the relationship between Bacteroides fragilis and CD? |
838 | Staphylococcus epidermidis | nosocomial infection | In Staphylococcus epidermidis, a human commensal bacterium, but also a cause of nosocomial infection together with S. aureus, the CRISPR-Cas system occurrence is very low, so classical phage therapy can be used as an alternative to kill this bacterium, although some strains carry CRISPR-Cas systems with spacers matchin... | positive | What is the relationship between Staphylococcus epidermidis and nosocomial infection? |
839 | Parabacteroides | HCC | (2018) reported that 13 genera, including Gemmiger and Parabacteroides, were enriched in early HCC following progression from cirrhosis to HCC. | relate | What is the relationship between Parabacteroides and HCC? |
840 | Fusobacterium animalis | CRC-related | For example, Zeller and Feng et al.showed that Porphyromonas asaccharolytica, Peptostreptococcus stomatis, Fusobacterium vincentii, and Fusobacterium animalis were predictive in the early diagnosis of colorectal cancer, which are among the tops of our list; in particular, F. nucleatum is a common CRC-related species wh... | positive | What is the relationship between Fusobacterium animalis and CRC-related? |
841 | Streptococcus | asthma | In addition, compared with noneosinophilic asthma, Firmicutes/Streptococcus and Actinomycetaceae were recently reported to be abundant in and positively associated with eosinophilic asthma. | positive | What is the relationship between Streptococcus and asthma? |
842 | Pseudomonas aeruginosa | LAD | A unique species detected in LAD was Pseudomonas aeruginosa, a bacterium not typically harbored in subgingival plaque, that is associated with severe infections in immunocompromised hosts including LAD patients [3]. | relate | What is the relationship between Pseudomonas aeruginosa and LAD? |
843 | Fusobacterium | neoplastic | Antibiotic treatment of Fusobacterium-positive colon cancers mice-xenografts reduces tumor growth, cancer cell proliferation along with Fusobacterium load, which favors the hypothesis that Fusobacterium species is associated with neoplastic progression (5, 6). | positive | What is the relationship between Fusobacterium and neoplastic? |
844 | Clostridium | MS | Furthermore, MS patients treated with glatiramer acetate showed an increase in Bacteroidaceae, Faecalibacterium, Ruminococcus, Lactobacillaceae, Clostridium, and other members of the class Clostridiales when compared with untreated MS patients. | na | What is the relationship between Clostridium and MS? |
845 | Blautia obeum | HD | On OTU level, we found an increase in Blautia obeum (or Ruminococcus obeum as it was previously termed32) in HD which may be an indicator of metabolic stress32. | positive | What is the relationship between Blautia obeum and HD? |
846 | Akkermansia muciniphila | tumor | Furthermore, at the species level, we also found that Alistipes shahii (Figure 6G), Akkermansia muciniphila (Figure 6H), Bacteroides thetaiotaomicron (Figure 6I), Bacteroides acidifaciens and Lactobacillus johnsonii (Figure S5) were increased in EcN-respond mice compared with tumor bearing controls. | na | What is the relationship between Akkermansia muciniphila and tumor? |
847 | Clostridium cocleatum | tumor | Interestingly, GpS treatment augmented the relative abundance of probiotics such as Clostridium cocleatum and Bacteroides acidifaciens modulated by tumor implantation [31]. | na | What is the relationship between Clostridium cocleatum and tumor? |
848 | Fn | CRC | Another study found that Fn can migrate with CRC cells to metastatic sites and that CRC patients may benefit from eradication of Fn with antibiotic treatment [53]. | relate | What is the relationship between Fn and CRC? |
849 | Eubacterium eligens | adenoma | At the species level, a significant increase in the levels of E. coli DNA was observed in the healthy samples compared to the adenoma and CRC samples (adjusted P value, <0.01) (Fig?1B) whereas the levels of Bifidobacterium catenulatum DNA and Eubacterium eligens DNA were decreased (adjusted P value, <0.01) (see Table S... | negative | What is the relationship between Eubacterium eligens and adenoma? |
850 | Clostridium | CD | Both clostridial clusters (Clostridium cluster IV, Clostridium cluster XIVa) were significantly lower in HFD groups compared to CD groups (p < 0.0001). | positive | What is the relationship between Clostridium and CD? |
851 | Bacteroides fragilis | CHD-NAFLD | The abundance of Bacteroides fragilis and Sutterella wadsworthensis was also the lowest in CHD-NAFLD patients (the abundance of Bacteroides fragilis in CHD-NAFLD, CHD, HCs: 0.13732, 0.7190, 0.4431; the abundance of Sutterella wadsworthensis in CHD-NAFLD, CHD, HCs: 0.1305, 0.1496, 0.2934). | negative | What is the relationship between Bacteroides fragilis and CHD-NAFLD? |
852 | acidophilus | mastitis | Intramammary inoculation of a commercial probiotic mixture of Lactobacillus acidophilus and Lactobacillus casei to cure mastitis has been found not to be efficient and caused a local inflammatory response [72]. | na | What is the relationship between acidophilus and mastitis? |
853 | Bacillus clausii | paediatric diarrhoea | Studies with Bacillus clausii did not assay for normal microbiota and had non-significant trial results for H. pylori eradication and the treatment of paediatric diarrhoea. | na | What is the relationship between Bacillus clausii and paediatric diarrhoea? |
854 | Lactobacillus casei | hyperinsulinemia | [19] demonstrated that, Dahi (containing probiotic Lactobacillus acidophilus and Lactobacillus casei), a traditional India fermented milk product, demonstrated an inhibitory effect on development of glucose intolerance, hyperglycemia, hyperinsulinemia, dyslipidemia, and oxidative stress in high fructose-induced diabeti... | negative | What is the relationship between Lactobacillus casei and hyperinsulinemia? |
855 | enterococcus | irritable bowel syndrome | Individually selected and cultured probiotic strains of lactobacillus or enterococcus were successfully tested in the clinic on patients with irritable bowel syndrome (IBS) and pneumonia (Suvorov, 2013). | na | What is the relationship between enterococcus and irritable bowel syndrome? |
856 | Enterococcus | autoimmune diseases | However, neither Enterococcus nor Sedimentibacter have been associated with dysbiosis in patients with RA or other autoimmune diseases. | na | What is the relationship between Enterococcus and autoimmune diseases? |
857 | Fusobacterium | tumor | (21) found that CD11b+ myeloid derived suppressive cells (MDSCs), including granulocytes/tumor associated neutrophils (TANs) and macrophages/tumor associated macrophages (TAMs), are more abundant in tumor tissues than normal tissue of Fusobacterium-fed APC Min mice. | na | What is the relationship between Fusobacterium and tumor? |
858 | Lactobacillus acidophilus | HD | [65] observed that two months of synbiotic supplementation (Lactobacillus acidophilus and Bifidobacterium bifidum in addition to inulin) altered the intestinal microbiota by increasing the count of Bifidobacteria in HD patients. | relate | What is the relationship between Lactobacillus acidophilus and HD? |
859 | Escherichia coli | tumor | Several bacterial populations, including Escherichia coli, Bacteroides fragilis, and Fusobacterium nucleatum, have been shown to directly influence tumor development in the colon. | relate | What is the relationship between Escherichia coli and tumor? |
860 | Escherichia coli | allergic airway inflammation | For example, intranasal exposure to the bacterium Escherichia coli was protective in the OVA-induced allergic airway inflammation model [34]. | negative | What is the relationship between Escherichia coli and allergic airway inflammation? |
861 | Bacteroides acidifaciens | tumor | Interestingly, GpS treatment augmented the relative abundance of probiotics such as Clostridium cocleatum and Bacteroides acidifaciens modulated by tumor implantation [31]. | na | What is the relationship between Bacteroides acidifaciens and tumor? |
862 | NTHi | COPD | Altered and abnormal TLR/PRR expression: inaccurate responses to NTHi The intrinsically reduced expression of TLRs in COPD patients may also contribute to the impaired pulmonary immune response thus facilitating NTHi persistent colonization. | positive | What is the relationship between NTHi and COPD? |
863 | Ruminococcus gnavus | IBD | The most striking change was a twofold to threefold increased abundance of Ruminococcus gnavus in SpA, as compared with both RA and HCs that was significantly correlated with the disease activity only in patients with a history of IBD. | na | What is the relationship between Ruminococcus gnavus and IBD? |
864 | Clostridium | ASD | Because this antibiotic is not absorbed in the gastrointestinal tract and its spectrum of action covers Gram-positive bacteria such as Clostridium, it is possible that these microorganisms play a role in ASD development, especially as vancomycin discontinuation led to a reversion of ASD symptoms [83]. | positive | What is the relationship between Clostridium and ASD? |
865 | Fusobacterium nucleatum | tumor | In the other hand, Helicobacter pylori was found to be differentially abundant between tumor and adjacent normal pairs with significant higher prevalence in adjacent tissue compared to tumor samples (n?=?23 and n?=?7, respectively), whereas Fusobacterium nucleatum was detected at very low abundance levels uniquely iden... | na | What is the relationship between Fusobacterium nucleatum and tumor? |
866 | Veillonella | oral squamous cell carcinomas | The elevated abundance of Streptococcus, Prevotella, and Veillonella in this study should be considered in future research to explore the feasibility of being a salivary diagnostic predictor in Jordanian smokers for oral squamous cell carcinomas. | positive | What is the relationship between Veillonella and oral squamous cell carcinomas? |
867 | parabacteroides | colitis | In particular, a decrease in the microbial diversity, a decrease in the proportion of the family Lachnospiraceae and Ruminoococcaceae, the increased level of the family Bacteroidaceae, the genus Bacteroides, and parabacteroides, and the increased levels of the species EF09600_s and EF604598 _s were similar to changes f... | positive | What is the relationship between parabacteroides and colitis? |
868 | Clostridium | RA | Beyond that, there were no statistically significant differences (p > 0.05) in relative expression units of Bifidobacterium (median: 195.7), Clostridium coccoides (median: 82.78), Clostridium coccoides-Eubacteria rectale (median: 60.17), Lactobacillus (median: 6.31), and Roseburia species (median: 795.1) in stool sampl... | na | What is the relationship between Clostridium and RA? |
869 | Fusobacterium | tumor | Metagenomic prediction suggested that Fusobacterium, Leptotrichia, and Streptococcus appear to be largely responsible for case-associated enrichment of tyrosine metabolism in both tumor:tumor-adjacent and tumor:fecal comparisons. | relate | What is the relationship between Fusobacterium and tumor? |
870 | Clostridium difficile | IBD | On the basis of the concept of repopulating the gut with a healthy microbiome, FMT has been successfully used in the treatment of Clostridium difficile infection (CDI), and recommended for other conditions such as inflammatory bowel disease (IBD), autoimmune disorders, certain allergic diseases, and metabolic disorders... | na | What is the relationship between Clostridium difficile and IBD? |
871 | Fusobacterium | RAS | LEfSe analysis focused on disease status unveiled discriminative association of the genera Lachnoanaerobaculum, Cardiobacterium, Leptotrichia, Fusobacterium, and the class Clostridia with Active RAS patients, whereas the genus Selenomonas was significantly associated with Passive RAS patients (Figure 1D). | relate | What is the relationship between Fusobacterium and RAS? |
872 | Ochrobactrum anthropi | endophthalmitis | In addition, in subject 5 we detected Ochrobactrum anthropi, an agent that had been identified previously in eye infections such as endophthalmitis and keratitis20,21. | positive | What is the relationship between Ochrobactrum anthropi and endophthalmitis? |
873 | Blautia wexlerae | cancer | In contrast, Blautia wexlerae is less represented in cancer samples than in noncancer samples (P?=?0.04424). | negative | What is the relationship between Blautia wexlerae and cancer? |
874 | Clostridium | liver NKT cell accumulation | Vancomycin treatment, which depletes Clostridium, can increase liver NKT cell accumulation and block liver cancer development [10, 13]. | negative | What is the relationship between Clostridium and liver NKT cell accumulation? |
875 | Parvimonas micra | periodontitis | When the microbiota around failed implants was examined, we observed that Parvimonas, a genus that includes the periodontal pathogen Parvimonas micra, and Oribacterium, a genus not associated with periodontitis (23), were elevated relative to healthy implants. | na | What is the relationship between Parvimonas micra and periodontitis? |
876 | Fusobacterium nucleatum | tumor | In addition, mucosa-associated E.coli belonging to the B2 phylogroup is found to be more prevalent in CRC tissues, and is identified to encode cyclomodulin which is vital for colon epithelia cell mutation [26].To explore subsequently, Fusobacterium nucleatum, which belongs to Fusobacteria, has been isolated from tumor ... | relate | What is the relationship between Fusobacterium nucleatum and tumor? |
877 | Clostridiales | Ulcerative Colitis | For example, Clostridiales Ruminococcaceae, the second most important taxon in the RFC model, significantly more abundant in Ent+ individuals, has been found to be underrepresented in individuals suffering from Crohn?s Disease and Ulcerative Colitis [27]. | negative | What is the relationship between Clostridiales and Ulcerative Colitis? |
878 | Escherichia coli | CD | Of these species, E. faecium and Escherichia coli had the highest linear discriminative analysis (LDA) scores in the UC and CD samples, respectively, compared with the HD samples (Fig?1a, b). | relate | What is the relationship between Escherichia coli and CD? |
879 | Streptococcus uberis | dysbacteriosis | Major pathogens such as Streptococcus uberis and Staphylococcus aureus were also found in milk from animals with no evidence of inflammatory reaction, suggesting the hypothesis that the development of mastitis can be regarded more as a dysbacteriosis than a primary infection [16]. | na | What is the relationship between Streptococcus uberis and dysbacteriosis? |
880 | Pseudomonas aeruginosa | occult bacterial infection | Specifically, the authors observed pathogen growth (e.g., Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae, Moraxella catarrhalis, Pseudomonas aeruginosa and Proteus mirabilis) in 8/22 (36%) IPF patients, suggesting that occult bacterial infection may contribute to the development of IPF. | na | What is the relationship between Pseudomonas aeruginosa and occult bacterial infection? |
881 | Klebsiella | CRC | In addition, Fusobacterium nucleatum also has a positive correlation with lymph node metastasis in CRC [27].Furthermore, Zhao and his colleagues study the stool samples of CRC patients in China, and found find that Bacteroides fragilis, Enterococcus, Escherichia/Shigella, Klebsiella, Streptococcus, and Peptostreptococc... | positive | What is the relationship between Klebsiella and CRC? |
882 | H. pylori | gastric cancer | Our results showed an underrepresentation of H. pylori among the gastric microbiota of the patients with gastric cancer, while Fusobacterium and Clostridium were frequently enriched. | negative | What is the relationship between H. pylori and gastric cancer? |
883 | Lactobacillus paracasei | colon carcinoma | In another study, Lactobacillus paracasei F19 and Bifidobacterium lactis BB12 were found to upregulate ANGPTL4 in the colon carcinoma HCT116 cell line in a dose and time dependent manner while Bacteroides thetaiotaomicron had no effect. | relate | What is the relationship between Lactobacillus paracasei and colon carcinoma? |
884 | Streptococcus salivarius | Cirrhotic | Cirrhotic patients with minimal HE (MHE) harbour a higher proportion of urease-producing Streptococcus salivarius in stool samples, positively correlating with serum ammonia accumulation13. | positive | What is the relationship between Streptococcus salivarius and Cirrhotic? |
885 | Ruminococcus gauvreauii | CAD | Therefore, the lower relative abundance of Ruminococcus gauvreauii in CAD patients in our study might be the consequence of greater prevalence of diabetes mellitus or higher dietary intake of advanced glycation end products which has been linked to increased risk of CAD [37]. | negative | What is the relationship between Ruminococcus gauvreauii and CAD? |
886 | C. albicans | candidiasis | The S. salivarius probiotic strain K12 inhibits adherence and filamentation of C. albicans, and in a murine model of infection candidiasis protected mice from severe candidiasis [82]. | na | What is the relationship between C. albicans and candidiasis? |
887 | Bacteroides caccae | tumor | (119) metastatic melanoma patients ICI (including ipilimumab, nivolumab, ipilimumab plus nivolumab, and pembrolizumab) Bacteroides caccae: enriched in all ICI responders High levels of anacardic acid, as microbial metabolites, could stimulate neutrophils and macrophages, and enhance T-cell recruitment to tumor metastas... | relate | What is the relationship between Bacteroides caccae and tumor? |
888 | Fusobacterium | liver cancer | Our previous study showed that the tongue coating microbiome is unique among other human body microbiomes, and revealed two specific genera, Oribacterium and Fusobacterium, that could distinguish liver cancer (LC) patients from healthy subjects [12]. | relate | What is the relationship between Fusobacterium and liver cancer? |
889 | Fusobacterium | CRC | Species level: Higher number of Fusobacterium rDNA copies correlated positively with that of Enterotoxigenic Bacteroides fragilis, E. faecalis in CRC tissue when compared to adjacent non-cancerous tissue Dejea et al[33] 2014 United States cohort: 30 CRCs, 6 adenomas and 22 healthy controls Malaysian cohort: 21 CRCs and... | positive | What is the relationship between Fusobacterium and CRC? |
890 | Bifidobacterium bifidum | colorectal cancer | We found some species that were distinctive of one disease only as it is the case for P. stomatis, P. micra and Gemella morbillorum in colorectal cancer, multiple Veillonella species in cirrhosis, and, partially, Bifidobacterium bifidum and Lachnospiraceae in IBD. | na | What is the relationship between Bifidobacterium bifidum and colorectal cancer? |
891 | Lactobacillus casei | cancer | In 1993, a phase III multicentered randomized controlled study on 223 patients with carcinoma of the uterine cervix showed that combining treatment with heat-killed Lactobacillus casei strains (LC9018) and radiation therapy enhanced tumor regression through the induction of immune response against cancer cells [119]. | relate | What is the relationship between Lactobacillus casei and cancer? |
892 | Psae | MDR Psae infection | In fact, fecal Psae carriage before ICU admission has been shown to be associated with an ~15-times increased risk for subsequent Psae-induced nosocomial infection (7), which might even more likely mount in a fatal outcome, given that particularly antibiotics-treated ICU patients with concomitant severe comorbidities i... | positive | What is the relationship between Psae and MDR Psae infection? |
893 | Ruminococcus torques | ASD | We found beta-hexosaminidase (K12373) significantly more abundant in ASD group (13,815.45 ? 3,547.44 and 3,582.57 ? 564.94 in ASD and HCs, respectively, p < 0.05 after FDR correction); we also observed that high abundance of the mucin-degrading enzyme in ASD patients was concurrent with the increased level of Ruminococ... | positive | What is the relationship between Ruminococcus torques and ASD? |
894 | Streptococcus | esophagitis | The ratio of Streptococcus (Firmicutes) to Prevotella (Bacteroidetes) in the stomach mucosa (corpus and antrum) has previously been negatively correlated with hiatal hernia length (30), and reduced relative abundance of Firmicutes in esophageal biopsy samples was previously shown to be associated with esophagitis and B... | negative | What is the relationship between Streptococcus and esophagitis? |
895 | Coprobacillus | NF | We observed that Lactobacillus, Coprobacillus and Anaerotruncus genera have a higher abundance not only in CKD patients respect to controls, but also in F respect to NF patients. | relate | What is the relationship between Coprobacillus and NF? |
896 | Clostridium | colitis | Mouse microbiota with higher level of genera Clostridium XI, Bifidobacterium, and Lactobacillus is associated with resistance to C. jejuni induced colitis. | negative | What is the relationship between Clostridium and colitis? |
897 | Clostridiales | IBS | Within the order Clostridiales, we noticed that conflicting results were reported for one family (Ruminococcaceae) being present at a high frequency in the included studies, with both increases (22,31) and decreases (26,31,32) being observed in patients with IBS. | relate | What is the relationship between Clostridiales and IBS? |
898 | Fusobacterium | colorectal adenomas | Our results for colorectal adenomas and increased Fusobacterium levels are similar to previously reported studies involving Fusobacterium and colorectal cancer [8], [10], [11]. | positive | What is the relationship between Fusobacterium and colorectal adenomas? |
899 | Clostridium | CF | Significantly higher abundance of Clostridium, Clostridium hiranosis, Eubacterium, and Faecalibacterium were found in CF patients who received AA therapy (S6 Table). | relate | What is the relationship between Clostridium and CF? |
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