TITLE: Differentiating the binomial coefficient
QUESTION [12 upvotes]: I took a lecture in combinatorics this semester and the professor did the following step in a proof: 
He showed that function $f: x \mapsto \binom{x}{r}$ is convex for $x > r - 1$ (in order to use Jensen's inequality on $f$) and did this in the following way:
"By the product-rule we have $$f''(x) = \frac{2}{r!} \sum_{0 \leq i < j \leq r - 1} \prod_{l = 0}^{r - 1} ( x - l) \frac{1}{(x - i ) (x - j)} \geq 0$$ for all $ x > r - 1$." I am a bit confused on his definition: How would one extend the binomial coefficient to $x \notin \mathbf{N}$? I first thought about piecewise linear interpolation, but then I can't differentiate it. I also thought of plugging in the Gamma-function for the factorials, but I doubt that this is the definition he used here. 
Can anyone explain to me what's happening here?
Thanks!

REPLY [6 votes]: As small supplement:

A generalisation of the binomial coefficient is used in the binomial series representation
  \begin{align*}
(1+x)^\alpha=\sum_{r=0}^\infty\binom{\alpha}{r}x^r\qquad\qquad |x|<1, \,\alpha\in\mathbb{C}
\end{align*}
  where the binomial coefficient
  \begin{align*}
\binom{\alpha}{r}=\frac{1}{r!}\alpha(\alpha-1)\cdots(\alpha-r+1)
\end{align*}
  can be defined even for complex $\alpha$. This implies that we can consider the binomial coefficient as real-valued (or complex-valued) polynomial of degree $r$
  \begin{align*}
&f:\mathbb{R}\rightarrow\mathbb{R}\\
&f(x)=\binom{x}{r}\\
&\qquad=\frac{1}{r!}x(x-1)\cdots(x-r+1)
\end{align*}
  which is so accessible to analytical operations (differentiation, etc.).

And you're right, it's not necessary to involve the Gamma-function here.