TITLE: Are there any open mathematical puzzles?
QUESTION [157 upvotes]: Are there any (mathematical) puzzles that are still unresolved? I only mean questions that are accessible to and understandable by the complete layman and which have not been solved, despite serious efforts, by mathematicians (or laymen for that matter)?
My question does not ask for puzzles that have been shown to have either no solution or multiple solutions (or have been shown to be ambiguously formulated).

REPLY [2 votes]: A somewhat forgotten problem from Paul Erdős is proving his following conjecture:
Let $f(r)$ equal the maximum of the sum of the side lengths of $r$ squares inscribed in a unit square such that they have no interior points in common. Erdős conjectured: For any positive integer $k$, $$f(k^2+1)=k.$$
As far as I know, this is not proven.