TITLE: What does a homogeneous space of a linear algebraic group know about the group?
QUESTION [7 upvotes]: Let $X=G/H$, where $G$ is a connected linear algebraic group over the field $\mathbf{C}$ of complex numbers
and $H\subset G$ is an algebraic subgroup.
In general, we can write the algebraic variety $X$ as $X=G'/H'$ with $G'$ non-isomorphic to $G$.
What can be said about $G'$ (and $H'$)?
Of course, we can always take any surjective homomorphism $G'\to G$, then $X$ is naturally a homogeneous space of $G'$.
Conversely, if the action of $G$ on $X$ is not effective, we can take a normal subgroup $N$ of $G$, contained in $H$
(say, the kernel of the action) and set $G'=G/N,\ H'=H/N$, then $X=G'/H'$. I am interested in less trivial examples.
I would be happy to get a general answer, but will be also grateful for special cases, examples, comments, etc.
I am obliged to Günter Harder for this nice title of my question.

REPLY [4 votes]: To add perspective to Dave's answer, it seems that homogeneous spaces realized as quotients of a connected reductive group $G$ by parabolic subgroups are often natural and rich in structure besides having close connections with $G$.  But I'm less confident about other types of homogeneous spaces.  There are lots of arbitrary constructions, e.g., start with a product of connected 1-dimensional groups and factor out the product of one or more of them.   At that extreme the homogeneous space has little connection with the given group.   
Even though factoring out a parabolic subgroup (especially a maximal one) tends to produce a relatively "small" variety, its automorphism group is often close to $G$ (as seen in Demazure's paper).    The only other type of maximal closed connected proper subgroup in $G$ is itself reductive, as follows from Borel-Tits theory in arbitrary characteristic: see for instance Section 30.4 of my Springer text GTM 21.    But then you get an affine homogeneous space.   In fact, R.W. Richardson's classic theorem  in Bull. London Math. Soc. 9 (1977) shows that $G/H$ is affine iff the closed subgroup $H$ of the reductive group $G$ is itself reductive.
All of which leads me to wonder how realistic it is in these affine cases to expect the homogeneous variety to know much about the given group?   In other words, I'm uncertain about how broad the statement of the original question should be.