TITLE: Is there a good definition of (topological) K-Theory over arbitrary spaces?
QUESTION [13 upvotes]: Hi
(this is my very first question here, so please don't hurt me...)
for some time now i've been looking for a sufficiently aesthetical definition of (topological) K-theory of arbitrary spaces, yet been unable to find or come up with one.   The definition I know goes as follows:     
For X connected, compact, hausdorff one defines $V(X) = \text{ set of isoclasses of vectorbundles over} X$ which becomes a comm. monoid under direct sum      and then $KO(X) = K(V(X))$  where the righthandside just means group completion of a comm monoid.
Here already the "isoclasses" of bundles bothers me, because this "set" is not really a set, is it? (?its elements being proper classes?). I guess this may be salvaged by instead looking at equi. classes of systems of transition functions taking values in $GL(\mathbb R)$, modulo some further restriction and relations !?
Anyway, this is something I might even live with, but
one goes on to show $KO(X) \cong [X, \mathbb Z \times BGL(\mathbb R)]$ for such spaces, and for a CW-complex C sets $KO(C) = [C, \mathbb Z \times BGL]$. This is the only possible defintion (up to nat. iso), when trying to end up with a cohomology-like functor; right?
Finally for a general space Z we pick (for every space simultaneously?!) a CW-substitue say C' and put $KO(Z) = [C', \mathbb Z \times BGL]$.    
However, using this as defintion, there really is very little beauty left in K-Theory for me. I know that just putting $KO(X) = K(V(X))$ goes awry (bundles must be allowed to have varying dimension over different components and in turn must allow for a partition of unity and so on...)   
So my question is:
Is there a way of altering the definition of V(X) sufficiently so as to give a "correct" definition of K-Theory?      Or some other way of producing these groups, nicely?     Nicely should in particular mean, without homotopy theory oder cell complexes, so that for instance homotopy invariance is not directly built into the definition.    And if so, what about relative groups, or even higher ones?
After all for singular cohomology and bordism there also are descriptions using homotopy theory (via Eilenberg-MacLane resp. Thom-Spaces) just as above, but for an arbtrary space there are entirely different (better?) descpriptions in terms of singular chains and manifolds.
Thanks in advance
Maybe I should add that passing to spectra makes everything even worse in my opinion.

REPLY [6 votes]: This is a response only to a tangential part of your question, on set theory, and not to the bulk.  It continues some of the discussion in the comments to Alain Valette's answer.
I guess the thing to emphasize is that in some technical sense you are correct: standard (e.g. ZFC) approaches to set theory often do not give meaning to sentences like "The set of isomorphism classes of all finite-dimensional vector bundles".  Certainly if you think that an "isomorphism class" is itself necessarily a "set" of things, and that the elements of a "set" should themselves be "sets", as is often done, that is.
But from a modern perspective, this is a perverse way to go about doing mathematics.  The notion of "the collection of isomorphism classes of finite-dimensional vector bundles" is perfectly good.  Moreover, there are many sets-with-structure that represent this notion.  So pick one --- for example, choose your favorite copy of $\mathbb R$, your favorite construction of $\mathrm{GL}(\mathbb R,n)$, etc., and form some set of transition functions and so on.  At the end of the day, whatever honest set you actually construct is just as good as any other.  The most important moral from category theory is that what you should mean by "the X" is "any object satisfying the distinguished properties of X, along with the instructions of how to make it isomorphic to any other object with the same distinguished properties".
Since you should not expect the Axiom of Choice, and other difficult things, to work for very large collections, it is important to worry about the "size" of a collection.  Most mathematicians only have two "sizes".  One size is called "is a set", and the other is called "is larger than a set".  Things like Choice are assumed to work without complication for anything that "is a set", and you may be more suspicious for "things larger than a set".  For this notion of "is a set", it certainly is true that the collection of isomorphism classes of finite-dimensional vector bundles "is a set".  Proof: represent it by a set in some way, I don't care how.
Anyway, in the comments to Alain's answer, it looks like you understand all of this perfectly well.  So don't sweat this part of the language!