TITLE: Examples of seemingly elementary problems that are hard to solve?
QUESTION [66 upvotes]: I'm looking for a list of problems such that
a) any undergraduate student who took multivariable calculus and linear algebra can understand the statements, (Edit: the definition of understanding here is that they can verify a few small cases by themselves )
b) but are still open or very hard (say took at least 5 years to solve),
Edit: c) and first proposed in the 20th century or later.
Edit : my motivation is to encourage students to addict to solving mathematical problems. 
I know that there are many such problems in number theory and combinatorics, for trivial example, Fermat's last theorem. I'll be more interested in other fields, but less famous problems in number theory or combinatorics would be also welcome. For example,
1) The $n!$ conjecture can be stated in an elementary language, but had been notoriously hard. See section 2.2 in Haiman's paper http://arxiv.org/abs/math.AG/0010246 . 
2) Let $r$ be any positive integer, and let $x_1, x_2$ be indeterminates. Consider the sequence $\{x_n\}$ defined by the recursive relation $$x_{n+1} =(x_n^r +1)/x_{n-1}$$
for any integer n. Prove that $x_n$ is of the form $P/Q$, where $P$ is a polynomial of $x_1$ and $x_2$ with non-negative coefficients, and Q is a monomial. This problem appeared as a special case of a conjecture by Fomin and Zelevinsky in the context of cluster algebras around 2001. They proved that $x_n$ can be written as $\frac{(\text{polynomial})}{(\text{monomial})}$. Proofs of positivity are recently obtained by Nakajima ( http://arxiv.org/abs/0905.0002 ) and Qin ( http://arxiv.org/abs/1004.4171 ).
3) Nagata conjecture : Let $r$ be a positive integer $\geq 10$, but not a square. Consider $r$ random points on the plane $R^2$. Let $m$ be any positive number. Prove that the degrees of plane curves passing through each of the $r$ points at least $m$ times are greater than $m\sqrt{r}$. See "Masayoshi Nagata, On the 14-th problem of Hilbert. Amer. J. Math. 81 (1959) 766–772". This is still wide open. 
I'll be grateful for any more examples.

REPLY [5 votes]: Consider all possible sequences $(x_1,\ldots,x_n)$ in $\mathbb{Z}^2$ such that $x_1=0$, $|x_{i+1}-x_i| = 1$, and $i\neq j \rightarrow x_i \neq x_j$. For any fixed $n$, there are only finitely many of them so we pick one uniformly at random. Question: what is the asymptotic behaviour of $R_n = \mathbb{E}\sup_{i\le n} |x_i|$ as $n \to \infty$? 
One trivially has $R_n \le n$ and $R_n \ge \sqrt{n/\pi}$. The conjecture (about 70 years ago by Flory) is that $R_n \approx n^{3/4}$. (The original argument apparently contained conceptual mistakes and reached the "correct" value somewhat by miracle. The modern argument is that if the self-avoiding random walk has a conformally invariant scaling limit, then it has to be one of the SLE($\kappa$), but SLE($8/3$) is the only one with the restriction property, so it has to be that one. The exponent then follows from the known self-similarity properties of SLE.)
To appreciate how far one is from proving this, consider that there is no theorem showing that there exists $\epsilon > 0$ such that either $R_n \lesssim n^{1-\epsilon}$ or $R_n \gtrsim n^{{1\over 2}+\epsilon}$! The best is a relatively recent article by Duminil-Copin and Hammond showing that $\lim_{n \to \infty} R_n/n = 0$... To the best of my knowledge, that argument does not provide any rate at all, so we still don't know that $R_n \lesssim n/\log\log n$ for example...