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41610063
2026
Assessment of Cardiovascular Risk Factors and Selected Echocardiographic Parameters in Male Patients with Psoriasis. Background: Psoriasis is associated with an increased risk of cardiovascular disease, including myocardial infarction and coronary artery disease. Material And Methods: This single-centre observational s...
41610064
2026
Slice-to-Volume Registration of the fetal thorax to assess observed/expected total fetal lungs volume in fetuses with congenital diaphragmatic hernia who underwent Fetoscopic Endoluminal Tracheal Occlusion. Objective: To evaluate the feasibility of slice-to-volume registration (SVR) of the fetal thorax in congenital di...
41610061
2026
Cerebral microbleed burden is associated with domain-specific cognitive impairment pattern in acute stroke. Objective: Cerebral microbleeds (CMBs) represent a key imaging marker of cerebral small vessel disease (CSVD). This study aimed to investigate the relationship between CMB burden and domain-specific cognitive imp...
41610062
2026
Cognitive impairment in patients with acute ischemic stroke after mechanical thrombectomy. Background: Post-stroke cognitive impairment is associated with increased mortality and healthcare costs. However, its characteristics in patients with large vessel occlusion after mechanical thrombectomy (MT) remain unclear. In ...
41610060
2026
Experimental Support for a Chiral Pentacoordinate, Axially Symmetric Cationic Mn(V)-Oxo Complex as the Key Reactant in the Highly Enantioselective Catalytic Epoxidation of Olefins. Reported herein are new results on the mechanism of action and scope of a recently discovered process for enantio- and position-selective e...
41610059
2026
The usefulness of the serum fibrinogen-to-albumin ratio as a preoperative predictor of HGD or IC in intraductal papillary mucinous neoplasm of the pancreas. Introduction The indications for resection of Intraductal papillary mucinous neoplasms (IPMNs) have been optimised according to the high-risk stigmata (HRS) and wo...
41610057
2026
Impact of Root Canal Filling Quality on Periapical Status and Root Resorption in Orthodontically Treated Teeth: A Retrospective Radiographic Study. Objective: To assess the influence of root canal obturation quality on periapical status after orthodontic treatment and evaluate the association between sex and root resor...
41610054
2026
A "Jack-of-All-Trades" Phototheranostic System Enabled by Strategic Regulation of Ferroptosis and PANoptosis for Cancer Therapy. Phototheranostic strategies for cancer remain constrained by the availability of phototheranostic agents. Nonfullerene acceptor (NFA) materials, characterized by their distinctive structure a...
41610058
2026
Dental Caries and Systemic Inflammation in Adolescents: Findings from a Population-Based Study. Objective: Dental caries, the most prevalent noncommunicable disease (NCD) in adolescence, may represent a hidden link to systemic inflammatory processes, a common underlying mechanism shared by all major NCDs. Accordingly, ...
41610056
2026
Education-Adjusted Interpretation of MMSE for Diagnostic Validity of Cognitive Disorders. Introduction The Mini-Mental State Examination (MMSE) is widely utilized in clinical settings for cognitive screening, yet its diagnostic accuracy is often influenced by demographic factors such as educational attainment. This stu...
41610055
2026
Intrapartum Point-of-Care Ultrasound (POCUS) may prevent cord prolapse in active labor: report of a case. Intrapartum point-of-care ultrasound (POCUS) is increasingly employed to assess fetal head position and labor progression. We describe a case in which intrapartum POCUS enabled the early detection of a compound cor...
41610053
2026
Predictive Factors for Abnormal Diagnostic Colonoscopy Findings among Pediatric Patients: A retrospective cohort study. Introduction: This study investigated predictive factors associated with abnormal diagnostic findings of pediatric colonoscopies. Methods: This retrospective study reviewed the medical records of chil...
41610052
2026
Examining the Influence of Task Complexity on Dual Task Performance in Parkinson's disease and Healthy Older Adults. Introduction: People with Parkinson's disease (PwPD) often experience difficulty performing dual-tasks (DT), negatively impacting mobility, fall risk and quality of life. The influence of task c...
41610051
2026
Tailoring Crosslinks through Time─A Paradigm for Tough Hydrogels. The multidisciplinary applications of hydrogels have motivated a thorough exploration of the relationship between their structural and mechanical properties, i.e., spatial structure-function relationships, with particular regard to strength and toughness...
41610050
2026
The Gastro-Intestinal Microbiota in Haematology. The gastro-intestinal (GI; gut) microbiota is important in the development and function of haematopoiesis. Abnormalities of the gut microbiota are termed dysbiosis which is associated with the development and prognosis of haematological disorders including clonal haemato...
41610047
2026
Measles Outbreak Associated with an Infectious Traveler - Colorado, May-June 2025. Measles is a highly contagious vaccine-preventable viral disease. Successful vaccination programs resulted in limited measles transmission in the United States in 2000, but U.S. cases have been increasing since early 2025. On May 20, 202...
41610048
2026
From Awareness to Participation: Diffusion of Innovation and Engagement of Older People in Barrier-Free Communities in Zhuhai, China. Barrier-free communities aim to let older adults and people with disabilities participate equally in city life by removing physical, informational, and service barriers. This study exami...
41610049
2026
Clinical Outcomes of VA-ECMO in acute and critical cardiac illnesses: A Single-Center Experience. Introduction: Acute and critical cardiac illnesses have attracted considerable attention because of their high mortality rates. Various innovative treatment methods including extracorporeal life support have been used to s...
41610046
2026
Low-cost smart blind cane and glasses with multi-level obstacle sensing, emergency alerts, and smart home integration. Objective: This study presents a low-cost assistive navigation system combining a Smart Blind Stick and Smart Glasses to improve mobility safety and independence for blind and visually impaired (BVI) u...
41610043
2026
Oncostatin M promotes chronic pain through direct regulation on nociceptors in rats. Abstract: Oncostatin M (OSM), a member of the interleukin 6 (IL-6) pro-inflammatory cytokine family, is upregulated in the dorsal root ganglia of patients with neuropathic pain and thus may be an important contributor to this condition...
41610037
2026
Multisystemic Imaging Features of Coccidioidomycosis. Coccidioidomycosis, a disease induced by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii, is endemic to the southwestern United States and occurs with a myriad of clinical and imaging manifestations, which range from limited pulmonary disease to ...
41610036
2026
Enhanced Myometrial Vascularity: Is It an Arteriovenous Malformation? Review of Definitions, Imaging Findings, and Management. Enhanced myometrial vascularity (EMV) is a common postpregnancy (ie, postpartum, postpregnancy termination, and postpregnancy loss) sonographic finding that represents involuting myometrial hyp...
41610035
2026
Distal Tibiofibular Syndesmosis: Anatomy, Biomechanics, Imaging Approach, and Postoperative Evaluation. The distal tibiofibular syndesmosis is a complex, predominantly fibrous joint comprised of the distal tibia and fibula and a stabilizing complex of ligaments that create a mortise for the talus, thereby facilitating ...
41610033
2026
Comparison of the EORTC QLQ PR25 and the FACT-P for assessing quality of life in patients with prostate cancer - an updated literature review. Purpose Of Review: Prostate cancer can significantly impact psychological, physical, and social well-being. This systematic review compares the development of the Functional Ass...
41610024
2026
An Autologous, Vascularized and Immunocompetent Tissue Engineered Skin to Highlight Inter-Individual Variability to Better Understand the Human Wound Healing. In vitro tissue-engineered skin models are valuable tools for dermatological research. Yet, they often fail to reproduce the complex interactions among vascular,...
41610030
2026
Behavioral and molecular characterization of various muscle-based surgical strategies for neuroma treatment in a peroneal nerve transection rat model. Abstract: Chronic pain resulting from neuroma formation is a prevalent and challenging problem to treat. Clinical studies suggest (1) surgically intervening at the time ...
41610028
2026
Differences in causal reasoning in preschool-aged children with and without autism. The abilities to reason probabilistically and infer causality at a distance support social inferences and emerge early in neurotypical development. We examined these capacities in 3- to 5-year-olds with and without autism. In Experiment...
41610029
2026
GraphReco: Probabilistic Structure Recognition for Chemical Molecules. In scientific documents, molecule structure information is usually delivered by chemical structure images. Although convenient for human interpretation, the image-based molecule structure depiction is not a machine-readable format, blocking producti...
41610027
2026
Office Hours Versus Non-Office-Hours Admissions to the Paediatric Intensive Care Unit: A Cohort Study on the Impact of Illness Severity on Length of Stay and Mortality. Aim: Paediatric intensive care unit (PICU) length of stay (LOS) significantly impacts healthcare resources and costs, yet the influence of admission ti...
41610026
2026
Parental investment across neighborhood contexts: Evidence from a randomized controlled trial of poverty reduction. This study investigated how low-income parents with infants and toddlers make differing caregiving investments depending on neighborhood conditions. It leverages a randomized controlled trial in which 1,0...
41610025
2026
Social working memory in adolescence. Little is known about how social network associations are tracked in cognition during adolescence, when social networks change in size and complexity. In 2023, 123 ethnically diverse adolescents and emerging adults (13-24 years; 52.9% female; 68.3% White; 18.7% Asian) completed a t...
41610023
2026
Nine years' experience of trial of labor after two previous cesarean sections at a tertiary hospital - A retrospective cohort study. Introduction: The global cesarean section (CS) rate has increased to 21.1% between 1990 and 2018. In Singapore, the annual CS rate has increased by ~ 0.6%, reaching an overall rate of 37....
41610022
2026
An Optical Sensing Strategy for Passive Magnetic-Field Measurement in IoT-Enabled Renewable Energy Systems. Intelligent sensing technologies are increasingly integrated into modern society to support a wide range of functions. Among these technologies, magnetic-field sensing plays a pivotal role in domains such as indu...
41610021
2026
Effects of Combined Psychological and Functional Exercise Interventions on Emotion, Life Quality, and Brain-Derived Neurotrophic Factor Levels in Patients With Parkinson's Disease: A Randomized Controlled Trial. ObjectiveTo evaluate the effects of a combined psychological and functional exercise intervention on emotion...
41610019
2026
Back to reality: Children's early temporal reasoning applies to real but not hypothetical events. Time words like "yesterday" and "tomorrow" are hard for children to learn, and for researchers to study, because their referents change from day to day. For example, "yesterday" means something different on Monday and on W...
41610018
2026
Southern and Rural U.S. Markets Exhibit the Highest Unmet Demand for Aesthetic Surgery: Insights from Google Search Data and Plastic Surgeon Distribution Across Designated Market Areas. Background: Optimizing plastic surgeon distribution is essential to meeting rising consumer demand for aesthetic operations. Objective...
41610017
2026
Evaluating the effectiveness of a parent-informed family math engagement resource. This study examined whether a parent-informed family math resource increased family math engagement during informal activities. Between 2022 and 2023, dyads of parents and preschoolers (N = 70; 3-4 years; 57% girls; 80% White, 11% Asian ...
41610016
2026
Longitudinal associations among maternal emotion regulation, maternal emotion-related socialization behaviors, and children's emotion regulation. Parents' emotion regulation (ER) may relate to their emotion-related socialization behaviors (ERSBs) and their children's ER, yet longitudinal, multimethod research on these ...
41610014
2026
Trend-Aligner: A Retention Time Modeling-Based Feature Alignment Method for Untargeted LC-MS Data Analysis. Liquid chromatography-mass spectrometry (LC-MS)-based multiomics studies require accurate cross-sample quantification and comparison of analyte abundances, but due to retention time (RT) shifts between runs, dedi...
41610011
2026
Immunoglobulin A-producing cells mediate the clinical benefits of metformin via interleukin-10. Metformin (MTF) is the primary treatment for type 2 diabetes, but its mechanisms for enhancing insulin sensitivity require thorough exploration. This study revealed that MTF improves insulin sensitivity by promoting the prol...
41610013
2026
Protocol to study mRNA levels during endoreplication in Arabidopsis thaliana through nuclei extraction and a sorting strategy. In plants, differentiation and expansion of some cell types is accompanied by exit from cell division and onset of endoreplication. Here, we describe a protocol to study changes in mRNA levels ...
41610005
2026
Multicomponent reactions with Meldrum's acid and isocyanides as a valuable synthetic approach: An update. Multicomponent reactions (MCRs) are one-pot processes in which at least three reactants are combined to assemble a novel target product by intrinsic molecular diversity, optimal atom economy, and high efficiency. T...
41610012
2026
METTL3/CD98-mediated glutamate efflux in CAFs drives CD8+ T cell exhaustion and impedes neoadjuvant immunochemotherapy. The role of neurotransmitters in suppressing anti-tumor immunity has garnered increasing attention. While glutamate has been extensively studied in neurological diseases, its potential role in regulat...
41610010
2026
α-Ketoglutarate couples cellular metabolism to developmental growth via hydroxylation-dependent degradation of Yorkie. The evolutionarily conserved Hippo signaling pathway, essential for development and tissue homeostasis, is intimately linked to cellular metabolism. While cellular α-ketoglutarate (α-KG) levels fluctua...
41610009
2026
Ccl12 coordinates immune-neural crosstalk to promote adipose sympathetic remodeling after burn trauma. Burn injury triggers sustained white adipose tissue (WAT) remodeling and hypermetabolism. While systemic catecholamines are considered primary drivers of this response, local mechanisms remain poorly defined. Here, we...
41610007
2026
A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise. A lack of consensus remains on whether normobaric hypoxia (NH) and hypobaric hypoxia (HH) may differentially impact physiological factors affecting cerebrovascular regulation, particularly with an additio...
41610001
2026
Synergistic Efficacy of Lactobacillus plantarum Supernatant-Preconditioned BM-MSCs in Alleviating Depression, Anxiety-Like Behavior, and Memory Impairment in a Rat Stress Model by Suppressing the NF-κB Pathway. Mesenchymal stem cells (MSCs)-based therapy has received considerable research attention for its anti-inflamm...
41610003
2026
Water-soluble platinum(II)-porphyrin based on oxygen response for cell hypoxia imaging. Biomedical imaging has become an essential tool in the field of early cancer diagnosis and treatment. It is of great significance to develop a method that can monitor tumor hypoxia in real time and maintain a good photodynamic thera...
41610002
2026
Self-Assessment Triage for Inflammatory Arthritis: A Pilot Randomized Controlled Trial. Objective: Prompt referral to a rheumatologist is essential for the prevention of joint damage in people with inflammatory arthritis (IA). We investigated whether rheumatology referrals can improve triage if additional information f...
41609999
2026
Controls on water-carbon coupling shift from climate to vegetation structure in the Minjiang River Basin. Water-carbon coupling shapes the stability of terrestrial carbon sinks, yet the magnitude, direction, and timing of interactions between surface runoff (Q) and gross primary productivity (GPP) can differ among hydr...
41610000
2026
Differentiation of focal liver lesions in contrast-enhanced ultrasound using a heuristic-guided hybrid machine-learning framework. Purpose: Sonazoid contrast-enhanced ultrasound (CEUS) offers valuable diagnostic information on hepatic lesions, but it is time-consuming. In this study, we investigated a novel composite m...
41609993
2026
New Pharmacological Treatment Approaches for Schizophrenia: Navigating the Post-iclepertin Landscape. Schizophrenia is a complex psychiatric disorder, with cognitive impairment representing a critical unmet medical need. Current treatments primarily address positive symptoms, failing to effectively improve cognitive fu...
41609998
2026
Moral Deference and the War in Gaza. This paper discusses the idea of moral deference in the context of the ongoing war in Gaza. This idea is particularly pertinent where many ethicists seem to share the sense that the Israeli onslaught in Gaza is immoral, and yet only few articulate it in writing. Moral deference, I s...
41609996
2026
Strengthening of Agbani clay with granite and characterization of its properties and toxicity for applications in building services. Developing countries with a high growth of young population are often faced with the burden of a housing deficit. Manufacture and utilization of locally abundant natural materials in buil...
41609995
2026
Optimized cementitious immobilization of simulated cesium and barium radionuclides in borate waste solution by natural zeolite additives. This study investigates the immobilization of cesium and barium contaminants in borate waste solutions using clinoptilolite-bearing and mordenite-bearing additives within cement matr...
41609994
2026
Behavioural Effects of Persistent Human Disturbance: A Playback Experiment in a Forest Bird. Increasing human presence and activities expose wild animals to persistent disturbances. Disturbed populations often become tolerant towards humans, although the underlying mechanisms are poorly understood. We used playback exp...
41609985
2026
Auxin accumulation in cereals after infection by Fusarium graminearum: putative biosynthetic pathways and preferences. Indole-3-acetic acid (IAA) is a major naturally occurring auxin that shows extensive accumulation in cereal plants during the first few days of infection by the phytopathogen Fusarium graminearum. Apar...
41609987
2026
Sleep and Behaviour in Early Autism: Examining Bidirectional Associations Near Diagnosis. Purpose: Sleep problems and behavioural challenges are examined rarely in very young autistic children. We investigated sleep in 173 autistic children, close to their autism diagnosis (Mage = 2.49 years at diagnosis), focussing on...
41609988
2026
Cultural Adaptation and Evaluation of the PEERS® Program for Autistic Young Adults in Iran: A Mixed-Methods Study. Purpose: This study evaluated the effectiveness of the Program for the Education and Enrichment of Relational Skills (PEERS®) for young autistic adults in Iran and explored participant and caregiver experi...
41609984
2026
Burden of gastric cancer in individuals aged 70 and older and possible risk factors from 1990 to 2021: a population-based study. This study analyses the incidence and death trends of gastric cancer in individuals aged 70 and older, and assesses the burden attributable to key risk factors, to inform targeted public heal...
41609981
2026
Effectiveness of a pharmacist-led deprescribing intervention in older inpatients: an implementation study with retrospective control group. Purpose: To determine the effectiveness of integrating a web-based tool into hospital pharmacist medication optimization activities on high-risk medication use and explore implemen...
41609982
2026
Characterization and biological activities of endophytic bacteria from Vernonia anthelmintica flowers. Endophytic bacteria associated with medicinal plants are a vital component of the plant microbiome and represent a valuable biological resource. This study investigates the diversity and biological activities of endop...
41609980
2026
Analgesic Efficacy and Adverse Effects of Epidural Ropivacaine Combined with Equipotent Alfentanil or Sufentanil for Labor Analgesia: A Multicenter Randomized Controlled Single-Blind Trial. Introduction: Epidural analgesia has shown high maternal-fetal safety and satisfactory analgesia. Sufentanil is associated with a ...
41609979
2026
VKORC1L1 Downregulation Induced Vitamin K Cycle Disorder Exacerbates Neuronal Ferroptosis After Spinal Cord Injury. Ferroptosis contributes significantly to neuronal loss and functional decline after spinal cord injury (SCI). Emerging evidence links the vitamin K (VK) cycle to ferroptosis regulation, but its status and...
41609977
2026
Insecticidal and Repellent Effects of Selected Botanicals against Tribolium Castaneum (Herbst) (Coleoptera: Tenebrionidae) with Reference To their Effect on Detoxifying Enzymes. The excessive application of various synthetic pesticides led to control difficulties, including insect resistance and environmental contamina...
41609978
2026
Current and Emerging Treatment Landscape of Common EGFR-Mutated Advanced Non-small Cell Lung Cancer. Osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has been standard of care as monotherapy for EGFR-mutated advanced non-small cell lung cancer since reporting of the FLA...
41609976
2026
DNA methylation analysis with nasal brushing for early diagnosis of sinonasal malignant tumours. Sinonasal tumours are rare entities presenting with non-specific symptoms, therefore being often misinterpreted. The present study aimed to evaluate if the 13-gene DNA Methylation assay for early cancer detection already as...
41609972
2026
Exploring the nexus between inflammation and mobility through the lens of healthy aging: current scenario and future perspectives. Aging is characterized by a progressive decline in physiological resilience and functional capacity, often accompanied by chronic, low-grade systemic inflammation, a phenomenon termed "infl...
41609975
2026
LipiFlow and the Transformation of Therapeutic Meibomian Gland Expression into Routine Clinical Practice. In 2011, meibomian gland dysfunction (MGD) was officially recognized as a condition that necessitated treatment with the goal of improving ocular symptoms. This was a tipping point in the understanding of MGD and t...
41609974
2026
Evaluating Systemic Immune-Inflammation Index and Mortality in Diabetic Retinopathy: A NHANES 2005-2018 Cohort Study. Introduction: Diabetic retinopathy (DR) is a leading cause of preventable blindness and is linked to excess mortality. Systemic inflammation plays a central role in DR pathogenesis, and the systemic imm...
41609966
2026
Serum miRNA-155 and TREM2 as Non-Invasive Biomarkers for Monitoring Neuroinflammation and Disease Activity in Multiple Sclerosis. Serum miRNA-155 and TREM2 levels were investigated as potential non-invasive indicators. In this case-control study, serum miRNA-155 and TREM2 levels were evaluated in 80 patients with multi...
41609973
2026
Exploring Dental Students' Perceptions of the Educational Environment: A Q-Sort-Based C-SWOT Analysis. Background: Dental education in India faces significant challenges, including reported high vacancy rates and perceived curriculum inadequacies. This study aimed to assess graduating dental students' perspectives on t...
41609971
2026
Clinical Impact of Droplet Digital PCR-Guided Antibiotic Stewardship on Prognosis in Patients with Suspected Bloodstream Infection: A Prospective Observational Study. Introduction: This study aimed to investigate whether droplet digital polymerase chain reaction (ddPCR) assay can be integrated with antimicrobial stewar...
41609969
2026
Family Perspectives on Pediatric Complementary and Integrative Medicine Practices in Pediatric Hematology and Oncology. Background: Families of children with cancer and nonmalignant blood disorders frequently explore complementary medicine (CM). Despite growing evidence supporting CM for pediatric populations, physicia...
41609968
2026
A Validated LC-MS/MS Method for Unbound Rifapentine Quantitation Reveals Nonlinear Plasma Protein Binding and Comparable Free Fractions Between Adults and Children with Tuberculosis. Background And Objective: Therapeutic drug monitoring (TDM) typically uses total drug concentration (Ct), but pharmacological effects dep...
41609967
2026
QSPR modeling of polychlorinated biphenyls using degree-based molecular descriptors: a comparative study with linear, polynomial, and ridge regression. Chemical graph theory provides a mathematical framework for representing molecular structures as graphs, where atoms correspond to vertices and chemical bonds to edges....
41609965
2026
Study on the Antagonistic Effects of Lycopene, Resveratrol, and Procyanidins on Male Reproductive Toxicity Induced by Nano Titanium Dioxide. To investigate the protective effects of three antioxidants-lycopene (LP), proanthocyanidins (PC), and resveratrol (RES)-against Nano-TiO2-induced reproductive toxicity in male mi...
41609962
2026
Delays in tuberculosis care among the top-ten-tuberculosis-high burden countries in the world: a scoping review. Background: Delayed diagnosis and treatment can be detrimental not only to patients but also to the community, as such delays can perpetuate TB transmission. This presents a significant challenge in the ongo...
41609963
2026
Two-stage inertial microfluidics enrichment of activated T-cells towards a bead-less chimeric antigen receptor manufacturing protocol. CAR-T cell therapy is leading the way in the field of cancer cell immunotherapies due to its high success rates. However, the manufacturing of CAR-T cells remains complex and expensive....
41609961
2026
Robust Inverse Reconstruction of Time-Varying Transmission Rates Across Model Structures and Incidence Forms. Accurate, decision-ready estimates of time-varying transmission rates are critical, yet thought to be sensitive to model specification. We test this sensitivity by applying a continuous inverse method to weekly...
41609959
2026
Omega-3 dietary supplementation combined with exercise to keep telomere integrity in the liver of aged obese female mice. Telomere shortening is a key marker of cellular aging and linked to pathologies such as liver disease. Oxidative stress and inflammation (hallmarks of obesity) contribute to telomere shortening, whi...
41609960
2026
Factors associated with emergency department length of stay in Alberta: a study of patient-, visit-, and facility-level factors using administrative health data. Purpose: The primary objective is to evaluate associations between emergency department (ED) total length of stay in Alberta and multiple patient-, visit-, an...
41609957
2026
Risk of myocardial infarction and stroke after breast cancer: an analysis of a population of 1.3 million women from North-West Italy. Purpose: Breast cancer (BC) is a leading public-health issue affecting women on a global scale. Thanks to the widespread implementation of screening programs and the improvement in thera...
41609958
2026
Zinc deficiency is associated with erythropoietin-stimulating agents hyporesponsive anemia in peritoneal dialysis patients: a cross-sectional study. Background: Zinc deficiency is widely recognized as a cause of anemia, but no studies have clarified the impact of zinc deficiency on achieving target hemoglobin levels in...
41609955
2026
Association between mental health problems and nocturnal enuresis among children and adolescents in Ethiopia. Background: Mental health problem impacts the life of children, adolescents, and their family. Different physiological factors were implicated as etiology of Nocturnal Enuresis (NE). Small body of research exam...
41609952
2026
Developments and Challenges in Treating Rheumatoid Arthritis-Related Interstitial Lung Disease: From Pathogenesis to Treatment Opportunities. Interstitial lung disease (ILD) is the most severe extra-articular manifestation of rheumatoid arthritis (RA), representing one the most frequent causes of death for patients wit...
41609956
2026
Parameter identification based on statistical and neural network approaches for the vegetation-water model. Turing patterns emerging from the vegetation-water model exhibit complex spatial and networked structures, while parameter identification of these patterns has become a challenging inverse problem. This paper aim...
41609953
2026
Deoxynivalenol-induced apoptosis and IL-1β modulation by fosfomycin in porcine immune and human intestinal epithelial cells. Deoxynivalenol is a trichothecene mycotoxin found in cereals and animal feed, causing immunotoxic and cytotoxic effects in both animals and humans. In pigs, deoxynivalenol induces immune cell apo...
41609954
2026
An epidemiological study estimating the burden of cancer risk in patients with Raynaud's phenomenon. Introduction/Objective: Raynaud's phenomenon (RP) is a common vasospastic condition that may develop secondary to cancer and/or in association with systemic autoimmune rheumatic diseases (SARDs). We aimed to estimate th...
41609947
2026
Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to Charlson Comorbidity Index: A post-hoc analysis of the DANFLU-1 randomized trial. Purpose: The DANFLU-1 trial suggested lower incidence of hospitalizations for pneumonia and influenza, respirat...
41609949
2026
Elevational variation in heart mass and suppression of hypoxia-induced right ventricle hypertrophy in Andean leaf-eared mice (Phyllotis). In lowland mammals that ascend to high elevation, hypoxia-induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right-vent...
41609948
2026
Roof-dependent atrial tachycardia after pulsed field ablation-mechanistic insights and predictive modeling for optimized ablation strategies: an ultra-high-density mapping study. Background And Aims: Pulsed field ablation (PFA) has emerged to an innovative approach to achieve pulmonary vein isolation (PVI) in atrial fi...
41609945
2026
Haploid Mutation Mapping Identifies a Homoeologous Non-Reciprocal Translocation Linked to Reduced Fibre and Enhanced Protein in Brassica napus. A key challenge for the genetic improvement of canola (Brassica napus), one of the world's most important oilseeds, is the limited natural variation for commercially important ...
41609946
2026
Unraveling heterogeneity in LUAD via multi-omics integration: molecular classification and therapeutic implications. Lung adenocarcinoma (LUAD) displays significant morphological and molecular heterogeneity both within and between tumors. This heterogeneity, coupled with the complexities of the tumor microenvironment (...
41609944
2026
Drivers and regional heterogeneity of cropland net ecosystem productivity across China's three major plains. Net ecosystem productivity (NEP) in croplands is a core indicator of carbon exchange between agroecosystems and the atmosphere, directly reflecting net carbon budgets and sequestration capacity. To resolve its s...
41609943
2026
Cytokine-induced senescence in tumors is based on sustained activation of STAT1- and NFκB-dependent gene regulatory signatures. Senescence is a tripartite cellular phenotype characterized by permanent growth arrest, resistance to apoptosis, and high secretory activity. Besides its physiological role in embryonic develo...
41609940
2026
LncRNA TUG1 promotes hepatic lipid accumulation by targeting the miR-29a-3p/SREBP-2/HMGCR axis in MAFLD. Metabolic-associated fatty liver disease (MAFLD) is a globally prevalent liver disorder, and long non-coding RNAs (lncRNAs) play a crucial role in its pathogenesis. However, the specific function of taurine up-regul...
41609942
2026
Rapid, Scalable, and Cost-Effective Manufacturing of Uniform Non-Enveloped, Tag-Free Virus-Like Particles. Virus-like particles (VLPs) are widely recognized as safe and versatile nanostructures with broad applications in vaccine development, gene delivery, and nanotechnology, but their production typically requires tim...
41609941
2026
Pancreatic Mucinous Cystic Neoplasms Following GLP-1 Receptor Agonists Use: A Report of Two Cases with Literature Review. Introduction And Importance: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), is increasingly used for glycemic control, weight loss, and cardiovascular risk reduction. While GLP-...
41609938
2026
Use of transcranial Doppler to determine brain death or death by neurologic criteria in children: a narrative review. Background: Transcranial Doppler (TCD) detects characteristic waveforms indicating cerebral circulatory arrest and has been widely applied as an ancillary test for adult brain death or death by neurolog...