prompt string | completion string | split string | pair_id string | ranking_query_id string | ranking_member_index int64 | ranking_candidate_row_count int64 | ranking_candidate_parent_count int64 | retrieval_parent_rank int64 | retrieval_parent_context_index int64 | retrieval_parent_context_count int64 | task_id string | source_id string | retrieval_strategy string | query_record_id string | retrieval_record_id string | query_benchmark_row_id string | retrieval_benchmark_row_id string | query_molecule_identity_key string | retrieval_molecule_identity_key string | query_smiles string | retrieval_smiles string | query_condition_group string | retrieval_condition_group string | query_condition_scope string | retrieval_condition_scope string | query_condition_atoms list | retrieval_condition_atoms list | candidate_context_relation string | query_source_record_count int64 | retrieval_source_record_count int64 | query_agreement_fraction float64 | retrieval_agreement_fraction float64 | query_gold_Y int64 | retrieval_gold_Y int64 | ranking_balance_label string | query_geometry_value float64 | retrieval_geometry_value float64 | absolute_geometry_difference float64 | calibration_sample_standard_deviation float64 | target_distribution dict | canonical_endpoint_key string | assay_concept string | measurement_kind string | metadata dict | absolute_canonical_value_difference float64 | standardized_canonical_value_difference float64 | sd_logistic_similarity float64 | target_train_sample_standard_deviation float64 | target_a float64 | target_b float64 | label_mode string | binary_label int64 | is_decisive bool | morgan_tanimoto_similarity float64 | graph_a_position int64 | graph_b_position int64 | graph_offset int64 | representation string | pair_bucket_key string | query_parent_id string | retrieval_parent_id string | query_scaffold string | retrieval_scaffold string | query_evidence dict | retrieval_evidence dict | bucket_total_record_count int64 | bucket_train_record_count int64 | bucket_train_parent_count int64 | evaluation_regime string | calibration_scope string | logit_geometry_transform string | query_source_payload_json string | retrieval_source_payload_json string | level string | level_family string | query_source_row_uid string | retrieval_source_row_uid string | upstream_pair_bucket_key string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>C=CCOC(Cn1ccnc1)c1ccc(Cl)cc1Cl</SMILES>
- Canonical assay context: micronucleus in cultured human lymphocytes
- Canonical measurement scale id: ames_mutagenicity_ordinal.v1
- Ch... | (B) | train | c87350b6f0abe3b9fe16ff1c20421611ea49d356efb19d60c47c2333b8e4d01b | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:b2f4d45ff1a209b03eb96510a0d21fe9ba28857087d7e8ff4c6d0c6254921f21 | ames:66bd390340d9672bcbd90daab128d062afc9fd966d547126f8aa7299b20e2502 | ames:b2f4d45ff1a209b03eb96510a0d21fe9ba28857087d7e8ff4c6d0c6254921f21 | ames:66bd390340d9672bcbd90daab128d062afc9fd966d547126f8aa7299b20e2502 | LEZWWPYKPKIXLL-UHFFFAOYSA-N | PZBPKYOVPCNPJY-UHFFFAOYSA-N | Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 | C=CCOC(Cn1ccnc1)c1ccc(Cl)cc1Cl | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in cultured human lymphocytes","L3"] | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in cultured human lymphocytes","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=micronucleus in cultured human lymphocytes",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=micronucleus",
"evidence_basis=current_study_experiment",
"experimental_context=in_vitro",
"metabolic_activation=no... | [
"canonical_assay_context=micronucleus in cultured human lymphocytes",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=micronucleus",
"evidence_basis=current_study_experiment",
"experimental_context=in_vitro",
"metabolic_activation=no... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 0 | 2 | 2 | 0.651784 | {
"nontransfer": 0.9999999999974246,
"transfer": 2.5753777441034436e-12
} | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in cultured human lymphocytes","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"micronucleus\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\",\"micronucleus in... | 2 | 3.068502 | 0 | 0.651784 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.714286 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in cultured human lymphocytes","L3"] | LEZWWPYKPKIXLL-UHFFFAOYSA-N | PZBPKYOVPCNPJY-UHFFFAOYSA-N | c1ccc(COC(Cn2ccnc2)c2ccccc2)cc1 | c1ccc(CCn2ccnc2)cc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 1,023 | 978 | 329 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"micronucleus in cultured human lymphocytes","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"micronucleus","evidence_basis":"current_study_experiment","experimental_context":"in_vitro","extra_details":... | {"canonical_assay_context":"micronucleus in cultured human lymphocytes","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"micronucleus","evidence_basis":"current_study_experiment","experimental_context":"in_vitro","extra_details":... | L3 | gold_v1 | sr_e4b10a4bacd444f296c3d8de1f0e31a3 | sr_60310d0affcb4553b5f096f87dcd5285 | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in cultured human lymphocytes"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>c1ccc2c(c1)cc1ccc3cc4ccccc4c4ccc2c1c34</SMILES>
- Canonical assay context: Mammalian cell gene mutation
- Canonical measurement scale id: ames_mutagenicity_ordinal.v1
- Chemical... | (B) | train | 2ff2e93659d36f1d3bf867f0b9e906c9d26ec98012510c564da1bbb13435ea9c | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:50faf87f2e5b479f3cb168292f05b89c61955815f91da7b10d2a05bfb1ae0fb5 | ames:7420a157594920b4a6160c19a06abf92bcd8829bb04842a77c03df7bf54e094f | ames:50faf87f2e5b479f3cb168292f05b89c61955815f91da7b10d2a05bfb1ae0fb5 | ames:7420a157594920b4a6160c19a06abf92bcd8829bb04842a77c03df7bf54e094f | GOHBXWHNJHENRX-UHFFFAOYSA-N | TUGYIJVAYAHHHM-UHFFFAOYSA-N | Cc1cc2ccccc2c2ccc3ccccc3c12 | c1ccc2c(c1)cc1ccc3cc4ccccc4c4ccc2c1c34 | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation","L3"] | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=Mammalian cell gene mutation",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=mammalian_cell_gene_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_vitro",
"metabolic_activation=not_repo... | [
"canonical_assay_context=Mammalian cell gene mutation",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=mammalian_cell_gene_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_vitro",
"metabolic_activation=not_repo... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 3 | 1 | 0.808398 | {
"nontransfer": 0.9997683731203013,
"transfer": 0.00023162687969869092
} | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"mammalian_cell_gene_mutation\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\",\... | 1 | 1.237015 | 0.000232 | 0.808398 | 0.000232 | 0.999768 | safety_canonical_v27 | 0 | true | 0.592593 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation","L3"] | GOHBXWHNJHENRX-UHFFFAOYSA-N | TUGYIJVAYAHHHM-UHFFFAOYSA-N | c1ccc2c(c1)ccc1c3ccccc3ccc21 | c1ccc2c(c1)cc1ccc3cc4ccccc4c4ccc2c1c34 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "3",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 3,
"aggregate_max": 3,
"aggregate_q1": 3,
"agg... | 756 | 717 | 382 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"Mammalian cell gene mutation","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"mammalian_cell_gene_mutation","evidence_basis":"cited_experiment","experimental_context":"in_vitro","extra_details":"Relat... | {"canonical_assay_context":"Mammalian cell gene mutation","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.75,"endpoint_name":"mammalian_cell_gene_mutation","evidence_basis":"cited_experiment","experimental_context":"in_vitro","extra_details":"Rela... | L3 | gold_v1 | sr_3e07f049a37d402a85aac4e8e7331a4c | sr_df6b36cb04024548a52b5d93eaf517b9 | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>O=Cc1c[nH]c2ccccc12</SMILES>
- Biological test system: Mammalia; NIH 3T3; fibroblast
- Canonical assay context: in vitro micronucleus assay
- Canonical measurement scale id: ame... | (A) | train | 97e06e7fa6d0d8b8317b77f59fbfe7eb5e8a4c155411365db39faaecbe34d95c | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:c8d4b1804014c33f4687051c34559f79f47b939a3ee5ece1ddeb952b6bf74176 | ames:82fef70e93172d85cd6a24d555f07188084e3764592ec3cd4bc1c2ca4ac15d3a | ames:c8d4b1804014c33f4687051c34559f79f47b939a3ee5ece1ddeb952b6bf74176 | ames:82fef70e93172d85cd6a24d555f07188084e3764592ec3cd4bc1c2ca4ac15d3a | WJCNZQLZVWNLKY-UHFFFAOYSA-N | OLNJUISKUQQNIM-UHFFFAOYSA-N | c1ccc2[nH]c(-c3cscn3)nc2c1 | O=Cc1c[nH]c2ccccc12 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vitro micronucleus assay","L3"] | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vitro micronucleus assay","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=Cricetulus griseus (Chinese hamster); CHO-K1 cells",
"canonical_assay_context=in vitro micronucleus assay",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=micronuclear_endpoint",
"endpoint_name=micronucleus_assay",
"study_context=in_vitro",
"unit... | [
"biological_test_system=Mammalia; NIH 3T3; fibroblast",
"canonical_assay_context=in vitro micronucleus assay",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=micronuclear_endpoint",
"endpoint_name=micronucleus_assay",
"study_context=in_vitro",
"unit_text=ordinal_outcome... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 0 | 0 | 0 | 0.902296 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vitro micronucleus assay","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"micronucleus_assay\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"in vitro micro... | 0 | 0 | 0.982014 | 0.902296 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.177778 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vitro micronucleus assay","L3"] | WJCNZQLZVWNLKY-UHFFFAOYSA-N | OLNJUISKUQQNIM-UHFFFAOYSA-N | c1ccc2[nH]c(-c3cscn3)nc2c1 | c1ccc2[nH]ccc2c1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 1,653 | 1,605 | 696 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"Cricetulus griseus (Chinese hamster); CHO-K1 cells","canonical_assay_context":"in vitro micronucleus assay","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.8,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"micronuclear_endpoint","endpoint_name"... | {"biological_test_system":"Mammalia; NIH 3T3; fibroblast","canonical_assay_context":"in vitro micronucleus assay","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.9,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"micronuclear_endpoint","endpoint_name":"micronucleus_assay"... | L3 | gold_v1 | sr_4f29ba2a20924bbd9301f8b8eb420a8e | sr_8c464d010e6841f3bea364ec13996256 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vitro micronucleus assay"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>Oc1c(Cl)cc(Cl)cc1Cl</SMILES>
- Canonical assay context: Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)
- Canonical measurement scale id: ames_mutagenicity_... | (A) | train | f404065fbf52ede3a0026f38e440e32d6176c68a14ddabc144855ee16007b061 | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:bb6521288721e25b25ae7876f4899b4f596aa7fbd05f83842b9985acb2cb0663 | ames:77a93619ca36e778408ca7ba73f9db425a81ed3219d50935147264620ebea896 | ames:bb6521288721e25b25ae7876f4899b4f596aa7fbd05f83842b9985acb2cb0663 | ames:77a93619ca36e778408ca7ba73f9db425a81ed3219d50935147264620ebea896 | NLZUEZXRPGMBCV-UHFFFAOYSA-N | LINPIYWFGCPVIE-UHFFFAOYSA-N | Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 | Oc1c(Cl)cc(Cl)cc1Cl | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)","L3"] | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=mammalian_cell_gene_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_... | [
"canonical_assay_context=Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=mammalian_cell_gene_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 2 | 2 | 0 | 0.727963 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"mammalian_cell_gene_mutation\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\",\... | 0 | 0 | 0.982014 | 0.727963 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.230769 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)","L3"] | NLZUEZXRPGMBCV-UHFFFAOYSA-N | LINPIYWFGCPVIE-UHFFFAOYSA-N | c1ccccc1 | c1ccccc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 1,142 | 1,076 | 364 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"mammalian_cell_gene_mutation","evidence_basis":"cited_experiment","experimental_co... | {"canonical_assay_context":"Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"mammalian_cell_gene_mutation","evidence_basis":"cited_experiment","experimental_co... | L3 | gold_v1 | sr_80f008008b724be2bb85aa1a89e0585b | sr_3e8615f434cb4726a4a1d276915ffbd8 | ["mutagenicity_outcomes","mammalian_cell_gene_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Mammalian cell gene mutation, TK locus (L5178Y mouse lymphoma cells)"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>CCc1cccc(CC)c1N(COC)C(=O)CCl</SMILES>
- Canonical assay context: plant chromosome aberration assay
- Canonical measurement scale id: ames_mutagenicity_ordinal.v1
- Chemical enti... | (A) | train | 0284d60081c594c10cbf503c31ef8ee0f74d5b813e9d57323c55d70e8523686b | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:5ab0697063de4da2c6e10bd4156acb0700c7aebe8002eaf7116738cb1e446c5a | ames:57b3249b49bfa0645f20e8d35e86636f02c0cae56739a442f0c07502b35b4ee7 | ames:5ab0697063de4da2c6e10bd4156acb0700c7aebe8002eaf7116738cb1e446c5a | ames:57b3249b49bfa0645f20e8d35e86636f02c0cae56739a442f0c07502b35b4ee7 | DQLWPEVFXSRNIQ-UHFFFAOYSA-N | XCSGPAVHZFQHGE-UHFFFAOYSA-N | CC(C)N(C(=O)CCl)c1ccccc1Cl | CCc1cccc(CC)c1N(COC)C(=O)CCl | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","plant chromosome aberration assay","L3"] | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","plant chromosome aberration assay","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=plant chromosome aberration assay",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=review_or_regulatory_synthesis",
"experimental_context=not_reported"... | [
"canonical_assay_context=plant chromosome aberration assay",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=cited_experiment",
"experimental_context=in_vitro",
"metabolic_act... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 2 | 2 | 0 | 0.454942 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","plant chromosome aberration assay","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"chromosome_aberration_or_clastogenicity\",\"ordinal_outcome_class\",\"ames_mutagenicity_ord... | 0 | 0 | 0.982014 | 0.454942 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.319149 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","plant chromosome aberration assay","L3"] | DQLWPEVFXSRNIQ-UHFFFAOYSA-N | XCSGPAVHZFQHGE-UHFFFAOYSA-N | c1ccccc1 | c1ccccc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 330 | 328 | 151 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"plant chromosome aberration assay","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"review_or_regulatory_synthesis","experimental_context":"no... | {"canonical_assay_context":"plant chromosome aberration assay","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.75,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"cited_experiment","experimental_context":"in_vitro","extr... | L3 | gold_v1 | sr_27cb68a6397e4c40a1eba74accc5f2f9 | sr_fabdd55da95b46bbb967b91ab189bcc1 | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","plant chromosome aberration assay"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1</SMILES>
- Canonical assay context: micronucleus in rat bone marrow immature/polychromatic erythrocytes
- Canonical measurement scale id: ames_mut... | (A) | train | 13625b0546d1194116f57284179c61dcd058d1af95796883fd7fd87572d6e813 | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:015bf332be1645eeb97697c93c615f09972228f20fcd77396da7493317430a63 | ames:e04bf5ec0c5d3f5e7d407964cb628ce9daee152ef656a92e576024af50d7a9b4 | ames:015bf332be1645eeb97697c93c615f09972228f20fcd77396da7493317430a63 | ames:e04bf5ec0c5d3f5e7d407964cb628ce9daee152ef656a92e576024af50d7a9b4 | CMSMOCZEIVJLDB-UHFFFAOYSA-N | JCKYGMPEJWAADB-UHFFFAOYSA-N | O=P1(N(CCCl)CCCl)NCCCO1 | O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1 | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in rat bone marrow immature/polychromatic erythrocytes","L3"] | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in rat bone marrow immature/polychromatic erythrocytes","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=micronucleus in rat bone marrow immature/polychromatic erythrocytes",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=micronucleus",
"evidence_basis=positive_control_or_reference_use",
"experimental_context=in_... | [
"canonical_assay_context=micronucleus in rat bone marrow immature/polychromatic erythrocytes",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=micronucleus",
"evidence_basis=current_study_experiment",
"experimental_context=in_vivo_nonh... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 2 | 2 | 0 | 0.774615 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in rat bone marrow immature/polychromatic erythrocytes","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"micronucleus\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\",\"micronucleus in... | 0 | 0 | 0.982014 | 0.774615 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.16 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in rat bone marrow immature/polychromatic erythrocytes","L3"] | CMSMOCZEIVJLDB-UHFFFAOYSA-N | JCKYGMPEJWAADB-UHFFFAOYSA-N | O=[PH]1NCCCO1 | c1ccccc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 416 | 393 | 147 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"micronucleus in rat bone marrow immature/polychromatic erythrocytes","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"micronucleus","evidence_basis":"positive_control_or_reference_use","experimental_co... | {"canonical_assay_context":"micronucleus in rat bone marrow immature/polychromatic erythrocytes","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"micronucleus","evidence_basis":"current_study_experiment","experimental_context":"i... | L3 | gold_v1 | sr_4f02cbad181e4ed5b91c627d5e99cb93 | sr_f7c74e54758e45c79efc467dbeaced5d | ["mutagenicity_outcomes","micronucleus","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","micronucleus in rat bone marrow immature/polychromatic erythrocytes"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>ClCC1CO1</SMILES>
- Canonical assay context: dominant lethal assay
- Canonical measurement scale id: ames_mutagenicity_ordinal.v1
- Chemical entity type: defined_chemical
- Endp... | (B) | train | f34b819d7106b68d09a11f14fabca38aa9d0a0140c6138812e8f51a6188a3a92 | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:657985e3db75ad3d974be2c205d13518f8a97826b019f2aaf10df415b11bd851 | ames:a7a5e8406fdde52864ae5cd5c636c4477b117dd7c5806aabfd0aa0addde85b21 | ames:657985e3db75ad3d974be2c205d13518f8a97826b019f2aaf10df415b11bd851 | ames:a7a5e8406fdde52864ae5cd5c636c4477b117dd7c5806aabfd0aa0addde85b21 | CMSMOCZEIVJLDB-UHFFFAOYSA-N | BRLQWZUYTZBJKN-UHFFFAOYSA-N | O=P1(N(CCCl)CCCl)NCCCO1 | ClCC1CO1 | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","dominant lethal assay","L3"] | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","dominant lethal assay","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=dominant lethal assay",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=germ_cell_or_heritable_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_vivo_nonhuman",
"metabolic_activation=not_... | [
"canonical_assay_context=dominant lethal assay",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=germ_cell_or_heritable_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_vivo_nonhuman",
"metabolic_activation=not_... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 0 | 2 | 0.968262 | {
"nontransfer": 0.9999999415781751,
"transfer": 5.84218249435847e-8
} | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","dominant lethal assay","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"germ_cell_or_heritable_mutation\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\... | 2 | 2.065558 | 0 | 0.968262 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.142857 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","dominant lethal assay","L3"] | CMSMOCZEIVJLDB-UHFFFAOYSA-N | BRLQWZUYTZBJKN-UHFFFAOYSA-N | O=[PH]1NCCCO1 | C1CO1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 772 | 751 | 244 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"dominant lethal assay","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"germ_cell_or_heritable_mutation","evidence_basis":"cited_experiment","experimental_context":"in_vivo_nonhuman","extra_details":"D... | {"canonical_assay_context":"dominant lethal assay","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"germ_cell_or_heritable_mutation","evidence_basis":"cited_experiment","experimental_context":"in_vivo_nonhuman","extra_details":"N... | L3 | gold_v1 | sr_a7805b3e2ff34fd8a777aaa7ad9f5473 | sr_afc040c5b5ba4876a7d84756de4db847 | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","dominant lethal assay"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>O=C(O)c1cc(O)c(O)c(O)c1</SMILES>
- Biological test system: animal; bone marrow
- Canonical assay context: in vivo micronucleus assay in bone marrow
- Canonical measurement scale... | (B) | train | b8f40b4e3b24a83924e4f74c34f04fd84c8fd889abd1af9644c628cfe968ac27 | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:30556ea3ed4fbedcf14d975323e3239db09f510b008f128f20fae9a47b6de36b | ames:e9d16caf09ab5cb4851252ab686c2ff7e0693d1c9d31e6b1b0d6ea9ba2bcd017 | ames:30556ea3ed4fbedcf14d975323e3239db09f510b008f128f20fae9a47b6de36b | ames:e9d16caf09ab5cb4851252ab686c2ff7e0693d1c9d31e6b1b0d6ea9ba2bcd017 | WMBWREPUVVBILR-WIYYLYMNSA-N | LNTHITQWFMADLM-UHFFFAOYSA-N | O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 | O=C(O)c1cc(O)c(O)c(O)c1 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=Mus musculus; bone marrow cells",
"canonical_assay_context=in vivo micronucleus assay in bone marrow",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"dose_or_concentration=EGCG 25 and 50 mg/kg b.wt.; arsenic 1.5 mg/kg b.wt.",
"dose_unit=mg/kg b.wt.",
"endpoint_cl... | [
"biological_test_system=animal; bone marrow",
"canonical_assay_context=in vivo micronucleus assay in bone marrow",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=micronuclear_endpoint",
"endpoint_name=micronucleus_assay",
"study_context=in_vivo_experimental",
"unit_text... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 0 | 2 | 2 | 0.961439 | {
"nontransfer": 0.9999999495435297,
"transfer": 5.0456470290419695e-8
} | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"micronucleus_assay\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"in vivo micron... | 2 | 2.080215 | 0 | 0.961439 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.282609 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | WMBWREPUVVBILR-WIYYLYMNSA-N | LNTHITQWFMADLM-UHFFFAOYSA-N | O=C(OC1Cc2ccccc2OC1c1ccccc1)c1ccccc1 | c1ccccc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 999 | 978 | 499 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"Mus musculus; bone marrow cells","canonical_assay_context":"in vivo micronucleus assay in bone marrow","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.75,"dose_or_concentration":"EGCG 25 and 50 mg/kg b.wt.; arsenic 1.5 mg/kg b.wt.","dose_unit":"mg/kg b.wt.","e... | {"biological_test_system":"animal; bone marrow","canonical_assay_context":"in vivo micronucleus assay in bone marrow","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.6,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"micronuclear_endpoint","endpoint_name":"micronucleus_as... | L3 | gold_v1 | sr_b6d57f7bcc8c48b08689696790086789 | sr_c4e88c91a49747aba4bb65dbed282580 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>CCN(N=O)C(N)=O</SMILES>
- Biological test system: ; ; ; peripheral blood reticulocytes (CD59-)
- Canonical assay context: in vivo micronucleus assay in peripheral blood reticulo... | (B) | train | 96f6d0743e1714765ee82b552532ccab5204bb2c6e375488c7db23269ef47ba9 | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:5edcc57108fc6eb8d963c60fdfb542010c51649a3e1a59a19f1c0e910e3a75d6 | ames:6cf1bc3b547d646e5b962db576a96e3e7350678f424f59135373693071574f43 | ames:5edcc57108fc6eb8d963c60fdfb542010c51649a3e1a59a19f1c0e910e3a75d6 | ames:6cf1bc3b547d646e5b962db576a96e3e7350678f424f59135373693071574f43 | WBNQDOYYEUMPFS-UHFFFAOYSA-N | FUSGACRLAFQQRL-UHFFFAOYSA-N | CCN(CC)N=O | CCN(N=O)C(N)=O | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in peripheral blood reticulocytes","L3"] | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in peripheral blood reticulocytes","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=Rattus norvegicus; rat; peripheral blood reticulocytes",
"canonical_assay_context=in vivo micronucleus assay in peripheral blood reticulocytes",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"dose_or_concentration=5",
"dose_unit=mg/kg/day",
"endpoint_class=micron... | [
"biological_test_system=; ; ; peripheral blood reticulocytes (CD59-)",
"canonical_assay_context=in vivo micronucleus assay in peripheral blood reticulocytes",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=micronuclear_endpoint",
"endpoint_name=micronucleus_assay",
"study... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 0 | 2 | 2 | 0.993672 | {
"nontransfer": 0.9999999009223275,
"transfer": 9.90776724737308e-8
} | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in peripheral blood reticulocytes","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"micronucleus_assay\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"in vivo micron... | 2 | 2.012736 | 0 | 0.993672 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.391304 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in peripheral blood reticulocytes","L3"] | WBNQDOYYEUMPFS-UHFFFAOYSA-N | FUSGACRLAFQQRL-UHFFFAOYSA-N | parent:WBNQDOYYEUMPFS-UHFFFAOYSA-N | parent:FUSGACRLAFQQRL-UHFFFAOYSA-N | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 273 | 244 | 126 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"Rattus norvegicus; rat; peripheral blood reticulocytes","canonical_assay_context":"in vivo micronucleus assay in peripheral blood reticulocytes","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.85,"dose_or_concentration":"5","dose_unit":"mg/kg/day","endpoint_cl... | {"biological_test_system":"; ; ; peripheral blood reticulocytes (CD59-)","canonical_assay_context":"in vivo micronucleus assay in peripheral blood reticulocytes","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.75,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"micronucle... | L3 | gold_v1 | sr_6b17abb191f14e1fa3a1f7771a180382 | sr_94c40d3ff82c4cf3a9ed62d6bf982ac7 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in peripheral blood reticulocytes"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>NS(=O)(=O)c1cc2c(cc1Cl)NCNS2(=O)=O</SMILES>
- Biological test system: Chinese hamster; ovary cells (CHO)
- Canonical assay context: chromosome aberration assay in CHO cells (in ... | (B) | train | eb2e5f4a962403c842f0bd9ba6eb57138b1d50cd520248d46b2d0603cc72e699 | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:8a3c955575b85a2e0846f02abdf49c045843e1ba747d736f2daa9ec0798ad576 | ames:39230455d8b972b186e7bad2fbc79ee6193c9456cd95c6d4c7490a284a5b5b27 | ames:8a3c955575b85a2e0846f02abdf49c045843e1ba747d736f2daa9ec0798ad576 | ames:39230455d8b972b186e7bad2fbc79ee6193c9456cd95c6d4c7490a284a5b5b27 | CMSMOCZEIVJLDB-UHFFFAOYSA-N | JZUFKLXOESDKRF-UHFFFAOYSA-N | O=P1(N(CCCl)CCCl)NCCCO1 | NS(=O)(=O)c1cc2c(cc1Cl)NCNS2(=O)=O | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay in CHO cells (in vitro, without exogenous activation)","L3"] | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay in CHO cells (in vitro, without exogenous activation)","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=Cricetulus griseus; Chinese hamster ovary (CHO)",
"canonical_assay_context=chromosome aberration assay in CHO cells (in vitro, without exogenous activation)",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"dose_or_concentration=50-500",
"dose_unit=µg/mL",
"endpoi... | [
"biological_test_system=Chinese hamster; ovary cells (CHO)",
"canonical_assay_context=chromosome aberration assay in CHO cells (in vitro, without exogenous activation)",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"dose_or_concentration=2600",
"dose_unit=µg/ml",
"endpoint_class=struct... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 0 | 2 | 0.982925 | {
"nontransfer": 0.9999999204931221,
"transfer": 7.950687781945072e-8
} | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay in CHO cells (in vitro, without exogenous activation)","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"chromosome_aberration_assay\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"chrom... | 2 | 2.034742 | 0 | 0.982925 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.089286 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay in CHO cells (in vitro, without exogenous activation)","L3"] | CMSMOCZEIVJLDB-UHFFFAOYSA-N | JZUFKLXOESDKRF-UHFFFAOYSA-N | O=[PH]1NCCCO1 | O=S1(=O)NCNc2ccccc21 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 247 | 245 | 155 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"Cricetulus griseus; Chinese hamster ovary (CHO)","canonical_assay_context":"chromosome aberration assay in CHO cells (in vitro, without exogenous activation)","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.8,"dose_or_concentration":"50-500","dose_unit":"\u00b... | {"biological_test_system":"Chinese hamster; ovary cells (CHO)","canonical_assay_context":"chromosome aberration assay in CHO cells (in vitro, without exogenous activation)","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.85,"dose_or_concentration":"2600","dose_unit":"\u00b5g/ml","endpoi... | L3 | gold_v1 | sr_4fe879c8788344f2a094c413d01933a3 | sr_27c91ac3e74341bdb0b2477f8548bfb9 | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay in CHO cells (in vitro, without exogenous activation)"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccccc2)cc1</SMILES>
- Canonical assay context: chromosome aberration assay
- Canonical measurement scale id: ames_fixed_mutation_ordinal.v1... | (A) | train | d8c0c9a12a68d904ec3894b6fee85742d746cd334f4d3d507368f82bed691fb9 | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:0c6ba68c2c43322a576c00fd9f7050e97d51d63adacbb5443c8b6c4d190a08f7 | ames:1a3b163ca3d98b39e16ca516fe9b7f12b6dcb14cd624da25edcf7c3bc8bdc2e9 | ames:0c6ba68c2c43322a576c00fd9f7050e97d51d63adacbb5443c8b6c4d190a08f7 | ames:1a3b163ca3d98b39e16ca516fe9b7f12b6dcb14cd624da25edcf7c3bc8bdc2e9 | JPIYZTWMUGTEHX-UHFFFAOYSA-N | VFCNQNZNPKRXIT-UHFFFAOYSA-N | CN(C)c1ccc(C(=N)c2ccc(N(C)C)cc2)cc1 | CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccccc2)cc1 | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay","L3"] | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=plant; root tip cells",
"canonical_assay_context=chromosome aberration assay",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=structural_chromosome_change",
"endpoint_name=chromosome_aberration_assay",
"unit_text=ordinal_outcome_class"
] | [
"canonical_assay_context=chromosome aberration assay",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=structural_chromosome_change",
"endpoint_name=chromosome_aberration_assay",
"unit_text=ordinal_outcome_class"
] | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 2 | 2 | 0 | 0.839528 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"chromosome_aberration_assay\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"chrom... | 0 | 0 | 0.982014 | 0.839528 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.388889 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay","L3"] | JPIYZTWMUGTEHX-UHFFFAOYSA-N | VFCNQNZNPKRXIT-UHFFFAOYSA-N | N=C(c1ccccc1)c1ccccc1 | [N+]=C1C=CC(=C(c2ccccc2)c2ccccc2)C=C1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 532 | 519 | 327 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"plant; root tip cells","canonical_assay_context":"chromosome aberration assay","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.5,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"structural_chromosome_change","endpoint_name":"chromosome_aberratio... | {"biological_test_system":null,"canonical_assay_context":"chromosome aberration assay","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.35,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"structural_chromosome_change","endpoint_name":"chromosome_aberration_assay","extra_de... | L3 | gold_v1 | sr_a6def9d3e7354a038f3796f028efdfe5 | sr_eb2a60582ffa4936b7c4d4be8f65467e | ["fixed_mutation","chromosome_aberration_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","chromosome aberration assay"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>Oc1ccc(O)cc1</SMILES>
- Canonical assay context: chromosome aberration/clastogenicity assay (unspecified)
- Canonical measurement scale id: ames_mutagenicity_ordinal.v1
- Chemic... | (A) | train | db4ccf2618e3857c87c63485f599bc11162968079e7365884ef9ff500532420f | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:02b3e616a47363cbcfa5e82715dd7e336c060dbc23794cef0b0daa1fa0e3ee8f | ames:6cf3f5dd0e38c30aabc290e4882158743ff518b7ed39f47c902e935f63059dbb | ames:02b3e616a47363cbcfa5e82715dd7e336c060dbc23794cef0b0daa1fa0e3ee8f | ames:6cf3f5dd0e38c30aabc290e4882158743ff518b7ed39f47c902e935f63059dbb | FJKROLUGYXJWQN-UHFFFAOYSA-N | QIGBRXMKCJKVMJ-UHFFFAOYSA-N | O=C(O)c1ccc(O)cc1 | Oc1ccc(O)cc1 | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration/clastogenicity assay (unspecified)","L3"] | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration/clastogenicity assay (unspecified)","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=chromosome aberration/clastogenicity assay (unspecified)",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=cited_experiment",
"experimental_context=in_v... | [
"canonical_assay_context=chromosome aberration/clastogenicity assay (unspecified)",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=cited_experiment",
"experimental_context=not_... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 2 | 2 | 0 | 0.584159 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration/clastogenicity assay (unspecified)","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"chromosome_aberration_or_clastogenicity\",\"ordinal_outcome_class\",\"ames_mutagenicity_ord... | 0 | 0 | 0.982014 | 0.584159 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.5 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration/clastogenicity assay (unspecified)","L3"] | FJKROLUGYXJWQN-UHFFFAOYSA-N | QIGBRXMKCJKVMJ-UHFFFAOYSA-N | c1ccccc1 | c1ccccc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 1,972 | 1,881 | 765 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"chromosome aberration/clastogenicity assay (unspecified)","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.65,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"cited_experiment","experimental_co... | {"canonical_assay_context":"chromosome aberration/clastogenicity assay (unspecified)","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.6,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"cited_experiment","experimental_con... | L3 | gold_v1 | sr_09c98ac3882a4eb196cf9d13a281a030 | sr_1eb8e1eb4af5480387ca605225542c20 | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration/clastogenicity assay (unspecified)"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>NC(=O)NO</SMILES>
- Canonical assay context: other mutation assay
- Canonical measurement scale id: ames_mutagenicity_ordinal.v1
- Chemical entity type: defined_chemical
- Endpo... | (B) | train | 6f24628f8ed07f8fd4607cf07b777d17a768792432e3cea55beec9830b833523 | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:849e8edd6a3e037dfb41351fb5cd1f3130cb55d9dccde2a9754740e6c2409615 | ames:01ee6e5b81289aec179b0802c36fb91efbe8ee9ca88e2cbf9f3edb6f86fc19ac | ames:849e8edd6a3e037dfb41351fb5cd1f3130cb55d9dccde2a9754740e6c2409615 | ames:01ee6e5b81289aec179b0802c36fb91efbe8ee9ca88e2cbf9f3edb6f86fc19ac | ZRKWMRDKSOPRRS-UHFFFAOYSA-N | VSNHCAURESNICA-UHFFFAOYSA-N | CN(N=O)C(N)=O | NC(=O)NO | ["mutagenicity_outcomes","other_mutation_assay","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","other mutation assay","L3"] | ["mutagenicity_outcomes","other_mutation_assay","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","other mutation assay","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=other mutation assay",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=other_mutation_assay",
"evidence_basis=positive_control_or_reference_use",
"experimental_context=in_vitro",
"metabolic_activation=not_rep... | [
"canonical_assay_context=other mutation assay",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=other_mutation_assay",
"evidence_basis=cited_experiment",
"experimental_context=not_reported",
"metabolic_activation=not_reported",
"mo... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 0 | 2 | 0.719424 | {
"nontransfer": 0.9999999999538918,
"transfer": 4.610822698381669e-11
} | ["mutagenicity_outcomes","other_mutation_assay","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","other mutation assay","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"other_mutation_assay\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\",\"other m... | 2 | 2.780003 | 0 | 0.719424 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.238095 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","other_mutation_assay","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","other mutation assay","L3"] | ZRKWMRDKSOPRRS-UHFFFAOYSA-N | VSNHCAURESNICA-UHFFFAOYSA-N | parent:ZRKWMRDKSOPRRS-UHFFFAOYSA-N | parent:VSNHCAURESNICA-UHFFFAOYSA-N | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 216 | 206 | 143 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"other mutation assay","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.85,"endpoint_name":"other_mutation_assay","evidence_basis":"positive_control_or_reference_use","experimental_context":"in_vitro","extra_details":"MNU... | {"canonical_assay_context":"other mutation assay","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.55,"endpoint_name":"other_mutation_assay","evidence_basis":"cited_experiment","experimental_context":"not_reported","extra_details":"Negative mutagen... | L3 | gold_v1 | sr_721454376f2c4fafba8599d6bc78688c | sr_43414e6067e0428aa48f391e456e2bb7 | ["mutagenicity_outcomes","other_mutation_assay","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","other mutation assay"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>O=C(O)CN(CC(=O)O)CC(=O)O</SMILES>
- Canonical assay context: Chromosome aberration (clastogenicity) in cultured mammalian cells
- Canonical measurement scale id: ames_mutagenici... | (B) | train | 744cb9030a28fd6cc6a9948924d3b65e226e93f5f61ea9eb1e0079ed3c9c4dda | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:dd1cb0b00c03ebfbefe1dc7731e19af625bf32c68ad26a2ccd51baa65bf3adba | ames:def20b147d53878ebeca6eb2f703591512e9144003ee5338d672e5fb9d827a6a | ames:dd1cb0b00c03ebfbefe1dc7731e19af625bf32c68ad26a2ccd51baa65bf3adba | ames:def20b147d53878ebeca6eb2f703591512e9144003ee5338d672e5fb9d827a6a | VSNHCAURESNICA-UHFFFAOYSA-N | MGFYIUFZLHCRTH-UHFFFAOYSA-N | NC(=O)NO | O=C(O)CN(CC(=O)O)CC(=O)O | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Chromosome aberration (clastogenicity) in cultured mammalian cells","L3"] | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Chromosome aberration (clastogenicity) in cultured mammalian cells","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=Chromosome aberration (clastogenicity) in cultured mammalian cells",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=current_study_experiment",
"experim... | [
"canonical_assay_context=Chromosome aberration (clastogenicity) in cultured mammalian cells",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=cited_experiment",
"experimental_co... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 0 | 2 | 0.509449 | {
"nontransfer": 0.9999999999999996,
"transfer": 4.87081933639683e-16
} | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Chromosome aberration (clastogenicity) in cultured mammalian cells","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"chromosome_aberration_or_clastogenicity\",\"ordinal_outcome_class\",\"ames_mutagenicity_ord... | 2 | 3.92581 | 0 | 0.509449 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.157895 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Chromosome aberration (clastogenicity) in cultured mammalian cells","L3"] | VSNHCAURESNICA-UHFFFAOYSA-N | MGFYIUFZLHCRTH-UHFFFAOYSA-N | parent:VSNHCAURESNICA-UHFFFAOYSA-N | parent:MGFYIUFZLHCRTH-UHFFFAOYSA-N | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 215 | 204 | 123 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"Chromosome aberration (clastogenicity) in cultured mammalian cells","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"current_study_experiment"... | {"canonical_assay_context":"Chromosome aberration (clastogenicity) in cultured mammalian cells","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"cited_experiment","experi... | L3 | gold_v1 | sr_6c31b029b7e44b58989b8297a12fce80 | sr_47e7f64ed30c4e15847de044ab233538 | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","Chromosome aberration (clastogenicity) in cultured mammalian cells"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>Nc1ccc(-c2ccccc2)cc1</SMILES>
- Biological test system: Homo sapiens; human tissues
- Canonical assay context: HPRT/HGPRT/XPRT forward mutation
- Canonical measurement scale id:... | (B) | train | 0119104f7159816effb08e99f1ee7ca4f536864605a9bf0ea87895193637903c | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:4b1f709af7ce139c11242755f0bc15521c331ad1ec475a12d34eb3170a29cd22 | ames:bba04c29e0884012c5642fc4d61ad918f51a883e0ab59234b621b171340076f1 | ames:4b1f709af7ce139c11242755f0bc15521c331ad1ec475a12d34eb3170a29cd22 | ames:bba04c29e0884012c5642fc4d61ad918f51a883e0ab59234b621b171340076f1 | OAKJQQAXSVQMHS-UHFFFAOYSA-N | DMVOXQPQNTYEKQ-UHFFFAOYSA-N | NN | Nc1ccc(-c2ccccc2)cc1 | ["fixed_mutation","hprt_hgprt_xprt_forward_mutation","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","HPRT/HGPRT/XPRT forward mutation","L3"] | ["fixed_mutation","hprt_hgprt_xprt_forward_mutation","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","HPRT/HGPRT/XPRT forward mutation","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=Cricetulus griseus; CHO; UV5 (NER mutant)",
"canonical_assay_context=HPRT/HGPRT/XPRT forward mutation",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=sequence_level_gene_change",
"endpoint_name=hprt_hgprt_xprt_forward_mutation",
"genetic_locus_or_... | [
"biological_test_system=Homo sapiens; human tissues",
"canonical_assay_context=HPRT/HGPRT/XPRT forward mutation",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=sequence_level_gene_change",
"endpoint_name=hprt_hgprt_xprt_forward_mutation",
"genetic_locus_or_chromosome_tar... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 0 | 2 | 2 | 0.983517 | {
"nontransfer": 0.9999999195144519,
"transfer": 8.048554815606733e-8
} | ["fixed_mutation","hprt_hgprt_xprt_forward_mutation","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","HPRT/HGPRT/XPRT forward mutation","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"hprt_hgprt_xprt_forward_mutation\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"... | 2 | 2.033519 | 0 | 0.983517 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.0625 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","hprt_hgprt_xprt_forward_mutation","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","HPRT/HGPRT/XPRT forward mutation","L3"] | OAKJQQAXSVQMHS-UHFFFAOYSA-N | DMVOXQPQNTYEKQ-UHFFFAOYSA-N | parent:OAKJQQAXSVQMHS-UHFFFAOYSA-N | c1ccc(-c2ccccc2)cc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 565 | 529 | 219 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"Cricetulus griseus; CHO; UV5 (NER mutant)","canonical_assay_context":"HPRT/HGPRT/XPRT forward mutation","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.8,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"sequence_level_gene_change","endpoint_name... | {"biological_test_system":"Homo sapiens; human tissues","canonical_assay_context":"HPRT/HGPRT/XPRT forward mutation","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.65,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"sequence_level_gene_change","endpoint_name":"hprt_hgprt... | L3 | gold_v1 | sr_4513303c48f843798a6ceaef228828cd | sr_a0ab1e335cce4391a3bb5c6d2970078f | ["fixed_mutation","hprt_hgprt_xprt_forward_mutation","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","HPRT/HGPRT/XPRT forward mutation"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>C[C@@H](N)Cc1ccccc1</SMILES>
- Biological test system: Mus musculus; mouse; bone marrow
- Canonical assay context: in vivo micronucleus assay in bone marrow
- Canonical measurem... | (A) | train | 847b27b23e310c0ec6d466667cd46dd1a68f6a726da8ef5447d5df95054cf99f | -1 | null | -1 | null | null | null | ames | fixed_mutation | limited_balanced_parent_morgan_first.v28_safety | ames:bb00a1aee3d2dfac39c102a223c9e200b3e3a668623111ae6cb4d180237240cf | ames:0384f32609361c575e78fe29a32a96fa97a4a955d9ba08415412687d45db2375 | ames:bb00a1aee3d2dfac39c102a223c9e200b3e3a668623111ae6cb4d180237240cf | ames:0384f32609361c575e78fe29a32a96fa97a4a955d9ba08415412687d45db2375 | BCGWQEUPMDMJNV-UHFFFAOYSA-N | KWTSXDURSIMDCE-MRVPVSSYSA-N | CN(C)CCCN1c2ccccc2CCc2ccccc21 | C[C@@H](N)Cc1ccccc1 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"biological_test_system=Mus musculus; bone marrow cells",
"canonical_assay_context=in vivo micronucleus assay in bone marrow",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=micronuclear_endpoint",
"endpoint_name=micronucleus_assay",
"study_context=in_vivo_experimental",
... | [
"biological_test_system=Mus musculus; mouse; bone marrow",
"canonical_assay_context=in vivo micronucleus assay in bone marrow",
"canonical_measurement_scale_id=ames_fixed_mutation_ordinal.v1",
"endpoint_class=micronuclear_endpoint",
"endpoint_name=micronucleus_assay",
"study_context=in_vivo_experimental",... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | near | 2 | 2 | 0 | 0.961439 | {
"nontransfer": 0.01798620996209155,
"transfer": 0.9820137900379085
} | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"fixed_mutation\",\"micronucleus_assay\",\"ordinal_outcome_class\",\"ames_fixed_mutation_ordinal.v1\",\"in vivo micron... | 0 | 0 | 0.982014 | 0.961439 | 0.982014 | 0.017986 | safety_canonical_v27 | 1 | true | 0.170732 | -1 | -1 | -1 | indirect_record | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow","L3"] | BCGWQEUPMDMJNV-UHFFFAOYSA-N | KWTSXDURSIMDCE-MRVPVSSYSA-N | c1ccc2c(c1)CCc1ccccc1N2 | c1ccccc1 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | 999 | 978 | 499 | id | train_exact_bucket.v27_safety | identity | {"biological_test_system":"Mus musculus; bone marrow cells","canonical_assay_context":"in vivo micronucleus assay in bone marrow","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.6,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"micronuclear_endpoint","endpoint_name":"mic... | {"biological_test_system":"Mus musculus; mouse; bone marrow","canonical_assay_context":"in vivo micronucleus assay in bone marrow","canonical_measurement_scale_id":"ames_fixed_mutation_ordinal.v1","confidence":0.8,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"micronuclear_endpoint","endpoint_name":"mi... | L3 | gold_v1 | sr_1774ede479834dd087147b8e2f9ae342 | sr_a5eec25112cc420ca73652f94dfba574 | ["fixed_mutation","micronucleus_assay","ordinal_outcome_class","ames_fixed_mutation_ordinal.v1","in vivo micronucleus assay in bone marrow"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O</SMILES>
- Canonical assay context: germ cell/heritable muta... | (B) | train | 2dc5034d8479653682246dc5aff6014a1a22745f4dd2fea3d73c239a254c40c4 | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:e511bdd8461ddc4ab9f9af027610cab7b79784fcd9ea9d5a6b2ba9fb20629fc6 | ames:4f11c0717648af912872a4f48ab5407ab960c6a948cb1ea7cb887f087c3667fa | ames:e511bdd8461ddc4ab9f9af027610cab7b79784fcd9ea9d5a6b2ba9fb20629fc6 | ames:4f11c0717648af912872a4f48ab5407ab960c6a948cb1ea7cb887f087c3667fa | NWIBSHFKIJFRCO-ICJNJQFQSA-N | VJJPUSNTGOMMGY-MRVIYFEKSA-N | CO[C@@]12C(COC(N)=O)C3=C(C(=O)C(C)=C(N)C3=O)N1C[C@@H]1N[C@@H]12 | COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","germ cell/heritable mutation in mouse spermatogonial stem cells","L3"] | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","germ cell/heritable mutation in mouse spermatogonial stem cells","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=germ cell/heritable mutation in mouse spermatogonial stem cells",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=germ_cell_or_heritable_mutation",
"evidence_basis=review_or_regulatory_synthesis",
"experimental... | [
"canonical_assay_context=germ cell/heritable mutation in mouse spermatogonial stem cells",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=germ_cell_or_heritable_mutation",
"evidence_basis=cited_experiment",
"experimental_context=in_vi... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 0 | 2 | 0.865137 | {
"nontransfer": 0.999999995019449,
"transfer": 4.980550947117091e-9
} | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","germ cell/heritable mutation in mouse spermatogonial stem cells","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"germ_cell_or_heritable_mutation\",\"ordinal_outcome_class\",\"ames_mutagenicity_ordinal.v1\... | 2 | 2.311773 | 0 | 0.865137 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.104762 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","germ cell/heritable mutation in mouse spermatogonial stem cells","L3"] | NWIBSHFKIJFRCO-ICJNJQFQSA-N | VJJPUSNTGOMMGY-MRVIYFEKSA-N | O=C1C=CC(=O)C2=C1CC1C3NC3CN21 | O=C1OCC2C(OC3CCC4OCOCC4O3)c3cc4c(cc3C(c3ccccc3)C12)OCO4 | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 77 | 77 | 19 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"germ cell/heritable mutation in mouse spermatogonial stem cells","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"germ_cell_or_heritable_mutation","evidence_basis":"review_or_regulatory_synthesis","exp... | {"canonical_assay_context":"germ cell/heritable mutation in mouse spermatogonial stem cells","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.85,"endpoint_name":"germ_cell_or_heritable_mutation","evidence_basis":"cited_experiment","experimental_con... | L3 | gold_v1 | sr_1b135212b99f46a2b83f3a9f8b4496ea | sr_249e87d843c843ddb407cf07c4de076a | ["mutagenicity_outcomes","germ_cell_or_heritable_mutation","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","germ cell/heritable mutation in mouse spermatogonial stem cells"] | |
You are comparing two experiments selected from similar assays.
The experimental details may differ.
Experiment A (known measurement)
<SMILES>N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O</SMILES>
- Canonical assay context: chromosome aberration in human peripheral blood lymphocytes
- Canonical measurement scale id: ... | (B) | train | 1e2a6a4c493d359f33b90e349d48c26087e486f3615bc4af2f6fc0b78a03cbb7 | -1 | null | -1 | null | null | null | ames | mutagenicity_outcomes | limited_balanced_parent_morgan_first.v28_safety | ames:b6c1e4fe2fd8a986b2a71cc3c79590236cc0a9bcb1d21662dcd67659cfe7e4d5 | ames:9fcf0b8c7b104c6340abe58d97ec7b9a0e001f8b9b0e8d6dc0c1b4402329544e | ames:b6c1e4fe2fd8a986b2a71cc3c79590236cc0a9bcb1d21662dcd67659cfe7e4d5 | ames:9fcf0b8c7b104c6340abe58d97ec7b9a0e001f8b9b0e8d6dc0c1b4402329544e | YKQOSKADJPQZHB-RGYSVOEGSA-N | RWSXRVCMGQZWBV-WDSKDSINSA-N | CCC(C)CCCC(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)C([C@@H](C)O)NC(=O)[C@@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O | N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration in human peripheral blood lymphocytes","L3"] | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration in human peripheral blood lymphocytes","L3"] | exact_v10_pair_bucket_and_level | exact_v10_pair_bucket_and_level | [
"canonical_assay_context=chromosome aberration in human peripheral blood lymphocytes",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=current_study_experiment",
"experimental_c... | [
"canonical_assay_context=chromosome aberration in human peripheral blood lymphocytes",
"canonical_measurement_scale_id=ames_mutagenicity_ordinal.v1",
"chemical_entity_type=defined_chemical",
"endpoint_name=chromosome_aberration_or_clastogenicity",
"evidence_basis=current_study_experiment",
"experimental_c... | same_exact_v10_pair_bucket_and_level | 1 | 1 | null | null | null | null | far | 2 | 0 | 2 | 0.690835 | {
"nontransfer": 0.9999999999854069,
"transfer": 1.4593137961383287e-11
} | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration in human peripheral blood lymphocytes","L3"] | L3 | ordinal | {
"calibration_sha256": "9fd24009a1018bfda1612454eaa043e432f41769b65b5c697dce9a6529856eeb",
"groups": {
"assay_concept": "L3",
"measurement_kind": "ordinal",
"query_condition_group": "[\"mutagenicity_outcomes\",\"chromosome_aberration_or_clastogenicity\",\"ordinal_outcome_class\",\"ames_mutagenicity_ord... | 2 | 2.895047 | 0 | 0.690835 | 0 | 1 | safety_canonical_v27 | 0 | true | 0.15625 | -1 | -1 | -1 | indirect_record | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration in human peripheral blood lymphocytes","L3"] | YKQOSKADJPQZHB-RGYSVOEGSA-N | RWSXRVCMGQZWBV-WDSKDSINSA-N | O=C1CCCNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CN1 | parent:RWSXRVCMGQZWBV-WDSKDSINSA-N | {
"aggregation_method": "individual_record",
"display_measurement_text": "2",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 2,
"aggregate_max": 2,
"aggregate_q1": 2,
"agg... | {
"aggregation_method": "individual_record",
"display_measurement_text": "0",
"display_unit_text": "ordinal_outcome_class",
"display_transform_id": "canonical_stage3.v10",
"source_record_count": 1,
"deduplicated_source_record_count": 1,
"aggregate_min": 0,
"aggregate_max": 0,
"aggregate_q1": 0,
"agg... | 2,593 | 2,535 | 640 | id | train_exact_bucket.v27_safety | identity | {"canonical_assay_context":"chromosome aberration in human peripheral blood lymphocytes","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.9,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"current_study_experiment","exper... | {"canonical_assay_context":"chromosome aberration in human peripheral blood lymphocytes","canonical_measurement_scale_id":"ames_mutagenicity_ordinal.v1","chemical_entity_type":"defined_chemical","confidence":0.8,"endpoint_name":"chromosome_aberration_or_clastogenicity","evidence_basis":"current_study_experiment","exper... | L3 | gold_v1 | sr_f7074e2eafab48d09fdea2f2457650f1 | sr_fec4a8c4b11e47d68f7bd63835645f54 | ["mutagenicity_outcomes","chromosome_aberration_or_clastogenicity","ordinal_outcome_class","ames_mutagenicity_ordinal.v1","chromosome aberration in human peripheral blood lymphocytes"] |
End of preview. Expand in Data Studio
Ames record-level V27 L3
This level-specific release uses current V10 physical evidence, the active Gold-owned level mapping, and Gold-v1 parent-disjoint evaluation. Undefined variance ratios are allowed; defined ratios above 0.65 are excluded. Prompts display canonical Stage-3 measurement and unit pairs.
Rows: {'train': 27728, 'validation_ranking': 25165, 'test_ranking': 24706}
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