Datasets:

jiosephlee
/

assay-transfer-record-level-v27-ames-l4-intern

prompt string	completion string	split string	pair_id string	ranking_member_index int64	ranking_candidate_row_count int64	ranking_candidate_parent_count int64	retrieval_parent_rank int64	retrieval_parent_context_index int64	retrieval_parent_context_count int64	task_id string	source_id string	retrieval_strategy string	query_record_id string	retrieval_record_id string	query_benchmark_row_id string	retrieval_benchmark_row_id string	query_molecule_identity_key string	retrieval_molecule_identity_key string	query_smiles string	retrieval_smiles string	query_condition_group string	retrieval_condition_group string	query_condition_scope string	retrieval_condition_scope string	query_condition_atoms list	retrieval_condition_atoms list	candidate_context_relation string	query_source_record_count int64	retrieval_source_record_count int64	query_agreement_fraction float64	retrieval_agreement_fraction float64	query_gold_Y int64	retrieval_gold_Y int64	ranking_balance_label string	query_geometry_value float64	retrieval_geometry_value float64	absolute_geometry_difference float64	calibration_sample_standard_deviation float64	target_distribution dict	canonical_endpoint_key string	assay_concept string	measurement_kind string	metadata dict	absolute_canonical_value_difference float64	standardized_canonical_value_difference float64	sd_logistic_similarity float64	target_train_sample_standard_deviation float64	target_a float64	target_b float64	label_mode string	binary_label int64	is_decisive bool	morgan_tanimoto_similarity float64	graph_a_position int64	graph_b_position int64	graph_offset int64	representation string	pair_bucket_key string	query_parent_id string	retrieval_parent_id string	query_scaffold string	retrieval_scaffold string	query_evidence dict	retrieval_evidence dict	bucket_total_record_count int64	bucket_train_record_count int64	bucket_train_parent_count int64	evaluation_regime string	calibration_scope string	logit_geometry_transform string	query_source_payload_json string	retrieval_source_payload_json string	level string	level_family string	query_source_row_uid string	retrieval_source_row_uid string	upstream_pair_bucket_key string
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>O=C(O)c1cccc(O)c1O</SMILES> - Assay version: immunoblot of phosphospecific antisera to ATM (Ser1981), p53 (Ser15), SMC1 (Ser957), Chk2 (Thr68) with densitometry - Biological sys...	(A)	train	0d0ec1be454d7bef28f710331a342cc88ebe14f5aafc122be4f700900293bfd8	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:300a0d68de5823a8e1e08ac95276bd3c3c27ad18dddb65948895f6a74f32c342	ames:00a5a4dee84e2076d909fdba1cafead38beee6f20095853100ff8c686c8b8ecb	ames:300a0d68de5823a8e1e08ac95276bd3c3c27ad18dddb65948895f6a74f32c342	ames:00a5a4dee84e2076d909fdba1cafead38beee6f20095853100ff8c686c8b8ecb	AKEUNCKRJATALU-UHFFFAOYSA-N	GLDQAMYCGOIJDV-UHFFFAOYSA-N	O=C(O)c1c(O)cccc1O	O=C(O)c1cccc(O)c1O	["premutagenic_damage","other_ddr_reporter_or_panel","signed_effect_direction","ames_damage_direction.v1","DDR phosphoprotein immunoblot","L4"]	["premutagenic_damage","other_ddr_reporter_or_panel","signed_effect_direction","ames_damage_direction.v1","DDR phosphoprotein immunoblot","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=immunoblot of phosphospecific antisera to ATM (Ser1981), p53 (Ser15), SMC1 (Ser957), Chk2 (Thr68) with densitometry", "biological_system=in vitro cells \| Homo sapiens \| MCF-7", "canonical_assay_context=DDR phosphoprotein immunoblot", "canonical_measurement_scale_id=ames_damage_direction.v1", ...	[ "assay_version=immunoblot of phosphospecific antisera to ATM (Ser1981), p53 (Ser15), SMC1 (Ser957), Chk2 (Thr68) with densitometry", "biological_system=in vitro cells \| Homo sapiens \| MCF-7", "canonical_assay_context=DDR phosphoprotein immunoblot", "canonical_measurement_scale_id=ames_damage_direction.v1", ...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	0	0	0	0.908505	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","other_ddr_reporter_or_panel","signed_effect_direction","ames_damage_direction.v1","DDR phosphoprotein immunoblot","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"other_ddr_reporter_or_panel\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"DDR ...	0	0	0.982014	0.908505	0.982014	0.017986	safety_canonical_v27	1	true	0.541667	-1	-1	-1	indirect_record	["premutagenic_damage","other_ddr_reporter_or_panel","signed_effect_direction","ames_damage_direction.v1","DDR phosphoprotein immunoblot","L4"]	AKEUNCKRJATALU-UHFFFAOYSA-N	GLDQAMYCGOIJDV-UHFFFAOYSA-N	c1ccccc1	c1ccccc1	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	79	79	62	id	train_exact_bucket.v27_safety	identity	{"assay_version":"immunoblot of phosphospecific antisera to ATM (Ser1981), p53 (Ser15), SMC1 (Ser957), Chk2 (Thr68) with densitometry","biological_system":"in vitro cells \| Homo sapiens \| MCF-7","canonical_assay_context":"DDR phosphoprotein immunoblot","canonical_measurement_scale_id":"ames_damage_direction.v1","confid...	{"assay_version":"immunoblot of phosphospecific antisera to ATM (Ser1981), p53 (Ser15), SMC1 (Ser957), Chk2 (Thr68) with densitometry","biological_system":"in vitro cells \| Homo sapiens \| MCF-7","canonical_assay_context":"DDR phosphoprotein immunoblot","canonical_measurement_scale_id":"ames_damage_direction.v1","confid...	L4	gold_v1	sr_b67f5e3c49c8456087641f3cd74a49c1	sr_39ca42420c2846dcb4131f23530f13a2	["premutagenic_damage","other_ddr_reporter_or_panel","signed_effect_direction","ames_damage_direction.v1","DDR phosphoprotein immunoblot"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>C[C@]12CC[C@H]3[C@@H](CCC4CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O</SMILES> - Biological system: in vivo \| Canis lupus familiaris \| prostate - Canonical assay context: 8-OHdG measurem...	(B)	train	8f7f27f77969ad415a451a091f9b230735b47a527fa4bbb3efdb3aa930a076f6	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:37dc3afcf515a095f7d45a4b077f9d64e636276cf5051c756ede267d4f2f2a1f	ames:52905d75663c225858b9abdc51faef368b8b8bd95faa7fa644b79318ef8ea6db	ames:37dc3afcf515a095f7d45a4b077f9d64e636276cf5051c756ede267d4f2f2a1f	ames:52905d75663c225858b9abdc51faef368b8b8bd95faa7fa644b79318ef8ea6db	UREBDLICKHMUKA-CXSFZGCWSA-N	NVKAWKQGWWIWPM-QHDNXLQLSA-N	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO	C[C@]12CC[C@H]3[C@@H](CCC4CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-OHdG measurement","L4"]	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-OHdG measurement","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "biological_system=in vivo \| Gallus gallus \| plasma", "canonical_assay_context=8-OHdG measurement", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=2.0", "dose_unit=mg/kg body weight", "endpoint_class=extracellular_damage_or_repair_product", "endpoint_name=oxidized_base...	[ "biological_system=in vivo \| Canis lupus familiaris \| prostate", "canonical_assay_context=8-OHdG measurement", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=oxidized_dna_base", "endpoint_name=oxidized_base_measurement", "endpoint_subtype=8-oxo-dG (8-hydroxydeoxyguanosine)", ...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	2	0	2	0.858311	{ "nontransfer": 0.9999999958558397, "transfer": 4.1441603880850485e-9 }	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-OHdG measurement","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"oxidized_base_measurement\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"8-OHdG...	2	2.330157	0	0.858311	0	1	safety_canonical_v27	0	true	0.184211	-1	-1	-1	indirect_record	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-OHdG measurement","L4"]	UREBDLICKHMUKA-CXSFZGCWSA-N	NVKAWKQGWWIWPM-QHDNXLQLSA-N	O=C1C=CC2C(=C1)CCC1C3CCCC3CCC21	O=C1CCC2C(CCC3C4CCCC4CCC23)C1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	3,357	3,307	617	id	train_exact_bucket.v27_safety	identity	{"assay_version":null,"biological_system":"in vivo \| Gallus gallus \| plasma","canonical_assay_context":"8-OHdG measurement","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.85,"dose_or_concentration":"2.0","dose_unit":"mg/kg body weight","endpoint_class":"extracellular_damage_or_repair_product...	{"assay_version":null,"biological_system":"in vivo \| Canis lupus familiaris \| prostate","canonical_assay_context":"8-OHdG measurement","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.9,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"oxidized_dna_base","endpoint_name":"oxidized...	L4	gold_v1	sr_52162c2ae33741068b29f414e5431a21	sr_d14ccc9f0a5241e2aa8c81a024bbddf4	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-OHdG measurement"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>O=S(=O)(c1ccc(O)cc1)c1ccc(O)cc1</SMILES> - Assay version: immunocytochemistry immunofluorescence (γH2AX) with co-localization of ~200 cells of 5 embryos per treatment - Biologic...	(B)	train	89f15270c5931d317a7d776e65791ac09a6c082c6faaff6e14b0a1d6d59baaa7	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:ddad1f75e24013c0fa6375461fc07df60d5b214c98aae42ba9db61e4904bedba	ames:c519cd154ebd5bdc9e94dd2348dc17be78d0223fecdf2224510ae46c49a78c1c	ames:ddad1f75e24013c0fa6375461fc07df60d5b214c98aae42ba9db61e4904bedba	ames:c519cd154ebd5bdc9e94dd2348dc17be78d0223fecdf2224510ae46c49a78c1c	RZVAJINKPMORJF-UHFFFAOYSA-N	VPWNQTHUCYMVMZ-UHFFFAOYSA-N	CC(=O)Nc1ccc(O)cc1	O=S(=O)(c1ccc(O)cc1)c1ccc(O)cc1	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","\u03b3H2AX immunostaining","L4"]	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","\u03b3H2AX immunostaining","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=γH2AX immunostaining (red nuclei)", "biological_system=in vitro cells \| Homo sapiens \| hTERT-FH-B (human fetal hepatoblast liver cells)", "canonical_assay_context=γH2AX immunostaining", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=7.5 (IC50)", "dose_unit...	[ "assay_version=immunocytochemistry immunofluorescence (γH2AX) with co-localization of ~200 cells of 5 embryos per treatment", "biological_system=F1 embryo (paternal germ-cell exposure) \| Teleostei \| blastoderm cells of 3.3 hpf embryos", "canonical_assay_context=γH2AX immunostaining", "canonical_measurement_sc...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	2	1	1	0.814744	{ "nontransfer": 0.9997449501161718, "transfer": 0.00025504988382814335 }	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","\u03b3H2AX immunostaining","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"gamma_h2ax_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"\\u03b3H2AX imm...	1	1.22738	0.000255	0.814744	0.000255	0.999745	safety_canonical_v27	0	true	0.333333	-1	-1	-1	indirect_record	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","\u03b3H2AX immunostaining","L4"]	RZVAJINKPMORJF-UHFFFAOYSA-N	VPWNQTHUCYMVMZ-UHFFFAOYSA-N	c1ccccc1	O=S(=O)(c1ccccc1)c1ccccc1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "0", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 1, "aggregate_max": 1, "aggregate_q1": 1, "a...	245	240	158	id	train_exact_bucket.v27_safety	identity	{"assay_version":"\u03b3H2AX immunostaining (red nuclei)","biological_system":"in vitro cells \| Homo sapiens \| hTERT-FH-B (human fetal hepatoblast liver cells)","canonical_assay_context":"\u03b3H2AX immunostaining","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.7,"dose_or_concentration":"7.5...	{"assay_version":"immunocytochemistry immunofluorescence (\u03b3H2AX) with co-localization of ~200 cells of 5 embryos per treatment","biological_system":"F1 embryo (paternal germ-cell exposure) \| Teleostei \| blastoderm cells of 3.3 hpf embryos","canonical_assay_context":"\u03b3H2AX immunostaining","canonical_measuremen...	L4	gold_v1	sr_fd5ace57802948f3b658a5c5512a3dd9	sr_cb609ad8c68a43538aeb10d7850d19a4	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","γH2AX immunostaining"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>CC(C)(C)OO</SMILES> - Assay version: single cell gel electrophoresis (SCGE), alkaline - Biological system: in vitro cells \| Homo sapiens \| AT21RM A-T lymphoblastoid cell line - ...	(A)	train	c52da86048bb4687b28796c029d69af08985341ec6d88c6c9f8aa1562a30c359	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:956b0c24bfc66f1fdf0a904ab464fa6ad72e24aab47fa90f1f6ce76518f413ea	ames:491075c56f7b313b3c79cf69411ccac22187ae15bfe2da87955db0e6c0dd4f33	ames:956b0c24bfc66f1fdf0a904ab464fa6ad72e24aab47fa90f1f6ce76518f413ea	ames:491075c56f7b313b3c79cf69411ccac22187ae15bfe2da87955db0e6c0dd4f33	MHAJPDPJQMAIIY-UHFFFAOYSA-N	CIHOLLKRGTVIJN-UHFFFAOYSA-N	OO	CC(C)(C)OO	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=alkaline comet, TMOM (tail moment)", "biological_system=in vitro cells \| endothelial cells", "canonical_assay_context=alkaline comet assay", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=300 µM", "dose_unit=µM", "endpoint_class=strand_break_or_alkali_la...	[ "assay_version=single cell gel electrophoresis (SCGE), alkaline", "biological_system=in vitro cells \| Homo sapiens \| AT21RM A-T lymphoblastoid cell line", "canonical_assay_context=alkaline comet assay", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=strand_break_or_alkali_labile_...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.786901	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"alkaline comet assay...	0	0	0.982014	0.786901	0.982014	0.017986	safety_canonical_v27	1	true	0.1	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay","L4"]	MHAJPDPJQMAIIY-UHFFFAOYSA-N	CIHOLLKRGTVIJN-UHFFFAOYSA-N	parent:MHAJPDPJQMAIIY-UHFFFAOYSA-N	parent:CIHOLLKRGTVIJN-UHFFFAOYSA-N	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	1,181	1,126	563	id	train_exact_bucket.v27_safety	identity	{"assay_version":"alkaline comet, TMOM (tail moment)","biological_system":"in vitro cells \| endothelial cells","canonical_assay_context":"alkaline comet assay","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.6,"dose_or_concentration":"300 \u00b5M","dose_unit":"\u00b5M","endpoint_class":"stran...	{"assay_version":"single cell gel electrophoresis (SCGE), alkaline","biological_system":"in vitro cells \| Homo sapiens \| AT21RM A-T lymphoblastoid cell line","canonical_assay_context":"alkaline comet assay","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.9,"dose_or_concentration":null,"dose_u...	L4	gold_v1	sr_522dcc416c2745419b58bf16ed09bd16	sr_0c148d89b4d5433fb12e6bd274ae9d89	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>CC(=O)N[C@@H](CS)C(=O)O</SMILES> - Assay version: γ-H2AX foci counting by fluorescence microscopy - Biological system: in vitro cells \| Homo sapiens \| peripheral blood lymphocyt...	(B)	train	62eb9eeab4d4302aa63fd7a367a0ee8e5d0b679931a3c250a3ea3f24a90347e8	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:fa81202f72acaebc702c1750e69308c873fc1374967cfc7c47153a02c4dcd02c	ames:a113a0b5e08f4342f02f0affc9fbb0d5d5baa6996ac16dae58f96617a1808db6	ames:fa81202f72acaebc702c1750e69308c873fc1374967cfc7c47153a02c4dcd02c	ames:a113a0b5e08f4342f02f0affc9fbb0d5d5baa6996ac16dae58f96617a1808db6	WOBHKFSMXKNTIM-UHFFFAOYSA-N	PWKSKIMOESPYIA-BYPYZUCNSA-N	C=C(C)C(=O)OCCO	CC(=O)N[C@@H](CS)C(=O)O	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","gamma-H2AX foci by immunofluorescence","L4"]	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","gamma-H2AX foci by immunofluorescence","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=γ-H2AX foci immunofluorescence (DSB marker)", "biological_system=in vitro cells \| Homo sapiens \| HGF (human gingival fibroblasts)", "canonical_assay_context=gamma-H2AX foci by immunofluorescence", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=1.12; 3.7; 11....	[ "assay_version=γ-H2AX foci counting by fluorescence microscopy", "biological_system=in vitro cells \| Homo sapiens \| peripheral blood lymphocytes", "canonical_assay_context=gamma-H2AX foci by immunofluorescence", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=dna_damage_response_s...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	2	0	2	0.780598	{ "nontransfer": 0.9999999995926689, "transfer": 4.0733103038077803e-10 }	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","gamma-H2AX foci by immunofluorescence","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"gamma_h2ax_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"gamma-H2AX foci...	2	2.562139	0	0.780598	0	1	safety_canonical_v27	0	true	0.171429	-1	-1	-1	indirect_record	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","gamma-H2AX foci by immunofluorescence","L4"]	WOBHKFSMXKNTIM-UHFFFAOYSA-N	PWKSKIMOESPYIA-BYPYZUCNSA-N	parent:WOBHKFSMXKNTIM-UHFFFAOYSA-N	parent:PWKSKIMOESPYIA-BYPYZUCNSA-N	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	685	662	335	id	train_exact_bucket.v27_safety	identity	{"assay_version":"\u03b3-H2AX foci immunofluorescence (DSB marker)","biological_system":"in vitro cells \| Homo sapiens \| HGF (human gingival fibroblasts)","canonical_assay_context":"gamma-H2AX foci by immunofluorescence","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.8,"dose_or_concentration...	{"assay_version":"\u03b3-H2AX foci counting by fluorescence microscopy","biological_system":"in vitro cells \| Homo sapiens \| peripheral blood lymphocytes","canonical_assay_context":"gamma-H2AX foci by immunofluorescence","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.85,"dose_or_concentratio...	L4	gold_v1	sr_10210095a59d4bfbae7e344113402e12	sr_1dbfb77fe40842e08b7af06677d67ee8	["premutagenic_damage","gamma_h2ax_assay","signed_effect_direction","ames_damage_direction.v1","gamma-H2AX foci by immunofluorescence"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>CC(C)Cc1ccc(C(C)C(=O)O)cc1</SMILES> - Assay version: single-cell gel electrophoresis (Comet assay); endpoints % Tail DNA and olive tail moment (OTM) - Biological system: in vitr...	(B)	train	32ca987fb5485109e1d5d87cdeed55a650e97e1edfb8e16892d2f10c6a3d6369	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:604db810ad4de0a828bc769952cbf2bf4b3dbc86e0e95781196a6feda82a9660	ames:5b52073127e6559b580054fecf6260ddddac21fb65d3d4d44638affd6a8f2c6e	ames:604db810ad4de0a828bc769952cbf2bf4b3dbc86e0e95781196a6feda82a9660	ames:5b52073127e6559b580054fecf6260ddddac21fb65d3d4d44638affd6a8f2c6e	FBOZXECLQNJBKD-ZDUSSCGKSA-N	HEFNNWSXXWATRW-UHFFFAOYSA-N	CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1	CC(C)Cc1ccc(C(C)C(=O)O)cc1	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (% tail DNA, olive tail moment)","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (% tail DNA, olive tail moment)","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "biological_system=in vitro cells \| SKOV-3 cell line", "canonical_assay_context=comet assay (% tail DNA, olive tail moment)", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=strand_break_or_alkali_labile_site", "endpoint_name=comet_assay", "endpoint_subtype=% tail DNA and Olive ...	[ "assay_version=single-cell gel electrophoresis (Comet assay); endpoints % Tail DNA and olive tail moment (OTM)", "biological_system=in vitro cells \| Homo sapiens \| peripheral whole blood cells", "canonical_assay_context=comet assay (% tail DNA, olive tail moment)", "canonical_measurement_scale_id=ames_damage_...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	2	1	1	0.784779	{ "nontransfer": 0.9998403608178194, "transfer": 0.00015963918218069386 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (% tail DNA, olive tail moment)","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"comet assay (% tail ...	1	1.274243	0.00016	0.784779	0.00016	0.99984	safety_canonical_v27	0	true	0.169014	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (% tail DNA, olive tail moment)","L4"]	FBOZXECLQNJBKD-ZDUSSCGKSA-N	HEFNNWSXXWATRW-UHFFFAOYSA-N	c1ccc(NCc2cnc3ncncc3n2)cc1	c1ccccc1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "0", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 1, "aggregate_max": 1, "aggregate_q1": 1, "a...	204	193	98	id	train_exact_bucket.v27_safety	identity	{"assay_version":null,"biological_system":"in vitro cells \| SKOV-3 cell line","canonical_assay_context":"comet assay (% tail DNA, olive tail moment)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.8,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"strand_break_or_alkali_labile...	{"assay_version":"single-cell gel electrophoresis (Comet assay); endpoints % Tail DNA and olive tail moment (OTM)","biological_system":"in vitro cells \| Homo sapiens \| peripheral whole blood cells","canonical_assay_context":"comet assay (% tail DNA, olive tail moment)","canonical_measurement_scale_id":"ames_damage_dire...	L4	gold_v1	sr_450dab6138e54778b7d1470b2b5880ab	sr_1be3bc8d3aa24877996279faaf4e1dcf	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (% tail DNA, olive tail moment)"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>CC(=O)O</SMILES> - Assay version: alkaline single-cell gel electrophoresis at pH >13 - Biological system: in vitro cells \| Homo sapiens \| peripheral blood cells (whole blood) - ...	(A)	train	93fe5fc2a60d90205c0750c985c1ab5060b94d81389bbaccb2ab7dfa696ef28b	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:e0c7a65c1172429b99082e055f04718cb326491326471beb63821b5336f2a12a	ames:2498f04b628c58a696d08bae4f8c00cf436973417f720748683104fc6aee437d	ames:e0c7a65c1172429b99082e055f04718cb326491326471beb63821b5336f2a12a	ames:2498f04b628c58a696d08bae4f8c00cf436973417f720748683104fc6aee437d	MHAJPDPJQMAIIY-UHFFFAOYSA-N	QTBSBXVTEAMEQO-UHFFFAOYSA-N	OO	CC(=O)O	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay (tail length)","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay (tail length)","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=alkaline comet assay (single-cell gel electrophoresis); DNA migration length measured by fluorescence microscopy", "biological_system=in vitro cells \| Tursiops truncatus \| leukocytes", "canonical_assay_context=alkaline comet assay (tail length)", "canonical_measurement_scale_id=ames_damage_dire...	[ "assay_version=alkaline single-cell gel electrophoresis at pH >13", "biological_system=in vitro cells \| Homo sapiens \| peripheral blood cells (whole blood)", "canonical_assay_context=alkaline comet assay (tail length)", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=0.5, 1...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.783666	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay (tail length)","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"alkaline comet assay...	0	0	0.982014	0.783666	0.982014	0.017986	safety_canonical_v27	1	true	0.285714	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay (tail length)","L4"]	MHAJPDPJQMAIIY-UHFFFAOYSA-N	QTBSBXVTEAMEQO-UHFFFAOYSA-N	parent:MHAJPDPJQMAIIY-UHFFFAOYSA-N	parent:QTBSBXVTEAMEQO-UHFFFAOYSA-N	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	388	362	159	id	train_exact_bucket.v27_safety	identity	{"assay_version":"alkaline comet assay (single-cell gel electrophoresis); DNA migration length measured by fluorescence microscopy","biological_system":"in vitro cells \| Tursiops truncatus \| leukocytes","canonical_assay_context":"alkaline comet assay (tail length)","canonical_measurement_scale_id":"ames_damage_directio...	{"assay_version":"alkaline single-cell gel electrophoresis at pH >13","biological_system":"in vitro cells \| Homo sapiens \| peripheral blood cells (whole blood)","canonical_assay_context":"alkaline comet assay (tail length)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.92,"dose_or_concentra...	L4	gold_v1	sr_ac394dac60404602b85acf37e8dbbf6c	sr_cf7dc64fff82440bad07b75b0c849527	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","alkaline comet assay (tail length)"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>COS(C)(=O)=O</SMILES> - Biological system: in vivo \| salmonid \| brown trout sperm - Canonical assay context: comet assay (tail DNA) - Canonical measurement scale id: ames_damage...	(A)	train	6a80cd2d8611bcc69069bd6c893f6d3effc8d572da4f21da0a4efbb9f945c05f	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:d051720e2900c01ee4e5a5fe8a19e5aa8a8f909330058c8e7e4b074399253d01	ames:baa220716f7458bfbf31747c1565ecef6df997bd6b07be3676aaac29ed5b80f2	ames:d051720e2900c01ee4e5a5fe8a19e5aa8a8f909330058c8e7e4b074399253d01	ames:baa220716f7458bfbf31747c1565ecef6df997bd6b07be3676aaac29ed5b80f2	PLUBXMRUUVWRLT-UHFFFAOYSA-N	MBABOKRGFJTBAE-UHFFFAOYSA-N	CCOS(C)(=O)=O	COS(C)(=O)=O	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (tail DNA)","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (tail DNA)","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "biological_system=whole plant exposure \| Lolium perenne \| leaf", "canonical_assay_context=comet assay (tail DNA)", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=30", "dose_unit=mM", "endpoint_class=strand_break_or_alkali_labile_site", "endpoint_name=comet_assay", "...	[ "biological_system=in vivo \| salmonid \| brown trout sperm", "canonical_assay_context=comet assay (tail DNA)", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=50", "dose_unit=mg/kg body weight", "endpoint_class=strand_break_or_alkali_labile_site", "endpoint_name=comet_as...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.65622	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (tail DNA)","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"comet assay (tail DN...	0	0	0.982014	0.65622	0.982014	0.017986	safety_canonical_v27	1	true	0.411765	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (tail DNA)","L4"]	PLUBXMRUUVWRLT-UHFFFAOYSA-N	MBABOKRGFJTBAE-UHFFFAOYSA-N	parent:PLUBXMRUUVWRLT-UHFFFAOYSA-N	parent:MBABOKRGFJTBAE-UHFFFAOYSA-N	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	196	187	115	id	train_exact_bucket.v27_safety	identity	{"assay_version":null,"biological_system":"whole plant exposure \| Lolium perenne \| leaf","canonical_assay_context":"comet assay (tail DNA)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.85,"dose_or_concentration":"30","dose_unit":"mM","endpoint_class":"strand_break_or_alkali_labile_site","e...	{"assay_version":null,"biological_system":"in vivo \| salmonid \| brown trout sperm","canonical_assay_context":"comet assay (tail DNA)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.9,"dose_or_concentration":"50","dose_unit":"mg/kg body weight","endpoint_class":"strand_break_or_alkali_labile_...	L4	gold_v1	sr_1043c8ae59954ca2b13b2c09504a7fe1	sr_66d88fd7f18e4f4089b1c1c44521db00	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (tail DNA)"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@@H](O)C2</SMILES> - Biological system: in vitro cells \| Rattus norvegicus \| Fao - Canonical assay context: comet assay (DNA damage) - Can...	(B)	train	1f5893ef839bf218e412697dda44be284f1e1a3852175a25908f4e3de1e28c32	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:cfa32408950dd09eadfe47fb13623bbe428b2ec9ae6f5e9fb40922ebd72fab69	ames:bd4f73c8398d10bcc5e81ce085459a4644fc2a0122f43d3094ed406e9ea52921	ames:cfa32408950dd09eadfe47fb13623bbe428b2ec9ae6f5e9fb40922ebd72fab69	ames:bd4f73c8398d10bcc5e81ce085459a4644fc2a0122f43d3094ed406e9ea52921	CWVRJTMFETXNAD-JUHZACGLSA-N	PFTAWBLQPZVEMU-DZGCQCFKSA-N	O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1C[C@](O)(C(=O)O)C[C@@H](O)[C@H]1O	Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@@H](O)C2	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (DNA damage)","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (DNA damage)","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "biological_system=in vitro cells \| lymphocytes", "canonical_assay_context=comet assay (DNA damage)", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=strand_break_or_alkali_labile_site", "endpoint_name=comet_assay", "endpoint_subtype=genetic damage index (GDI)", "molecule_role...	[ "biological_system=in vitro cells \| Rattus norvegicus \| Fao", "canonical_assay_context=comet assay (DNA damage)", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=strand_break_or_alkali_labile_site", "endpoint_name=comet_assay", "endpoint_subtype=DNA damage scored 0-4", "molecu...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	1	0	1	0.843672	{ "nontransfer": 0.99961154553646, "transfer": 0.00038845446354000124 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (DNA damage)","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"comet assay (DNA dam...	1	1.185295	0.000388	0.843672	0.000388	0.999612	safety_canonical_v27	0	true	0.212121	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (DNA damage)","L4"]	CWVRJTMFETXNAD-JUHZACGLSA-N	PFTAWBLQPZVEMU-DZGCQCFKSA-N	O=C(C=Cc1ccccc1)OC1CCCCC1	c1ccc(C2CCc3ccccc3O2)cc1	{ "aggregation_method": "individual_record", "display_measurement_text": "0", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 1, "aggregate_max": 1, "aggregate_q1": 1, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	1,605	1,525	693	id	train_exact_bucket.v27_safety	identity	{"assay_version":null,"biological_system":"in vitro cells \| lymphocytes","canonical_assay_context":"comet assay (DNA damage)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.85,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"strand_break_or_alkali_labile_site","endpoint_name":...	{"assay_version":null,"biological_system":"in vitro cells \| Rattus norvegicus \| Fao","canonical_assay_context":"comet assay (DNA damage)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.7,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"strand_break_or_alkali_labile_site","endp...	L4	gold_v1	sr_ccd5d6fed8a647c682f013d12a6ef903	sr_7a73ce2398314433a34fc4e2605c0c7c	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (DNA damage)"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>CC(=O)Nc1sc2c(c1-c1nc3ccccc3s1)CN(C(C)C)C2</SMILES> - Assay version: fluorescence-based HTS APE1 inhibition assay - Biological system: in vitro enzyme assay \| purified APE1 enzy...	(A)	train	6aef61795110925ad5d94ef277602ab8438c6938aa9b57e2c0bd9d0426066449	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:f1a2f6b8d5ddcf2b8536ed6f6912016c2cc42ab0e4f436b46d15f20f959dc2cd	ames:53ea10cd025410f0322faa45330e967549e89eaf43385ef2c56eb0c712ed2d32	ames:f1a2f6b8d5ddcf2b8536ed6f6912016c2cc42ab0e4f436b46d15f20f959dc2cd	ames:53ea10cd025410f0322faa45330e967549e89eaf43385ef2c56eb0c712ed2d32	JMSPCTGDYFVMJZ-UHFFFAOYSA-N	CZIACNCULOWAAI-UHFFFAOYSA-N	CC(=O)Nc1sc2c(c1-c1nc3ccccc3s1)CCN(C(C)C)C2	CC(=O)Nc1sc2c(c1-c1nc3ccccc3s1)CN(C(C)C)C2	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","APE1 AP endonuclease activity","L4"]	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","APE1 AP endonuclease activity","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=radiotracer incision assay (RIA) of APE1 endonuclease activity", "biological_system=cell-free enzyme assay \| APE1 (AP endonuclease 1)", "canonical_assay_context=APE1 AP endonuclease activity", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=repair_activity_capacity_...	[ "assay_version=fluorescence-based HTS APE1 inhibition assay", "biological_system=in vitro enzyme assay \| purified APE1 enzyme", "canonical_assay_context=APE1 AP endonuclease activity", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=repair_activity_capacity_or_lesion_removal", "...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	0	0	0	0.728387	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","APE1 AP endonuclease activity","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"repair_activity_or_kinetics\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"APE1...	0	0	0.982014	0.728387	0.982014	0.017986	safety_canonical_v27	1	true	0.836364	-1	-1	-1	indirect_record	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","APE1 AP endonuclease activity","L4"]	JMSPCTGDYFVMJZ-UHFFFAOYSA-N	CZIACNCULOWAAI-UHFFFAOYSA-N	c1ccc2sc(-c3csc4c3CCNC4)nc2c1	c1ccc2sc(-c3csc4c3CNC4)nc2c1	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	110	108	56	id	train_exact_bucket.v27_safety	identity	{"assay_version":"radiotracer incision assay (RIA) of APE1 endonuclease activity","biological_system":"cell-free enzyme assay \| APE1 (AP endonuclease 1)","canonical_assay_context":"APE1 AP endonuclease activity","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.9,"dose_or_concentration":null,"d...	{"assay_version":"fluorescence-based HTS APE1 inhibition assay","biological_system":"in vitro enzyme assay \| purified APE1 enzyme","canonical_assay_context":"APE1 AP endonuclease activity","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.85,"dose_or_concentration":null,"dose_unit":null,"endpoi...	L4	gold_v1	sr_2ae0cbad550c4fdc8c86fbb350f36905	sr_73200b2907f747f6af8535ac0e4da066	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","APE1 AP endonuclease activity"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>c1ccc([C](c2ccccc2)c2ccccc2)cc1</SMILES> - Assay version: alkaline single-cell gel electrophoresis (comet) assay - Biological system: in vivo gavage + ex vivo comet \| Rattus (ra...	(B)	train	2c2a30bc49a947aa24bcdba74f00a6cd8af6a7de38f1b510276c0e0d48ab6f03	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:1c4560e8ac340ff65904821a02d303bc468e80f7c77d98248ff3207de5e0fc97	ames:e84a4e1a8ff92a6b73493e9e1350055f852020fe557015c5e9abde7767a63f93	ames:1c4560e8ac340ff65904821a02d303bc468e80f7c77d98248ff3207de5e0fc97	ames:e84a4e1a8ff92a6b73493e9e1350055f852020fe557015c5e9abde7767a63f93	MHAJPDPJQMAIIY-UHFFFAOYSA-N	OHSJPLSEQNCRLW-UHFFFAOYSA-N	OO	c1ccc([C](c2ccccc2)c2ccccc2)cc1	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (single-strand breaks)","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (single-strand breaks)","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=comet assay", "biological_system=in vitro cells \| Homo sapiens \| Jurkat", "canonical_assay_context=comet assay (single-strand breaks)", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=strand_break_or_alkali_labile_site", "endpoint_name=comet_assay", "endpoint_su...	[ "assay_version=alkaline single-cell gel electrophoresis (comet) assay", "biological_system=in vivo gavage + ex vivo comet \| Rattus (rat) \| colon mucosal cells", "canonical_assay_context=comet assay (single-strand breaks)", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=40"...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	2	1	1	0.838254	{ "nontransfer": 0.9996401864571735, "transfer": 0.0003598135428265895 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (single-strand breaks)","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"comet assay (single-...	1	1.192956	0.00036	0.838254	0.00036	0.99964	safety_canonical_v27	0	true	0.166667	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (single-strand breaks)","L4"]	MHAJPDPJQMAIIY-UHFFFAOYSA-N	OHSJPLSEQNCRLW-UHFFFAOYSA-N	parent:MHAJPDPJQMAIIY-UHFFFAOYSA-N	c1ccc([C](c2ccccc2)c2ccccc2)cc1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "0", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 1, "aggregate_max": 1, "aggregate_q1": 1, "a...	269	257	147	id	train_exact_bucket.v27_safety	identity	{"assay_version":"comet assay","biological_system":"in vitro cells \| Homo sapiens \| Jurkat","canonical_assay_context":"comet assay (single-strand breaks)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.8,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"strand_break_or_alkali_l...	{"assay_version":"alkaline single-cell gel electrophoresis (comet) assay","biological_system":"in vivo gavage + ex vivo comet \| Rattus (rat) \| colon mucosal cells","canonical_assay_context":"comet assay (single-strand breaks)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.9,"dose_or_concent...	L4	gold_v1	sr_07712dabd7e24e7dac23805b8142ef67	sr_1573a85c23fe43bc8f3c91e34b7ffdfe	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","comet assay (single-strand breaks)"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>O=NOO</SMILES> - Assay version: 8-oxoG measurement (sensitive assay, unspecified format) - Canonical assay context: 8-oxoguanine measurement - Canonical measurement scale id: am...	(A)	train	af39e06fbaee06efcb48863a0f61ca16531e42621bc581d6f838b9c918a0ad1b	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:9f2de8b891914ce2bed57ef5528c2902367f1790d303740ce75c6f4241bdbc5c	ames:76494b07796c1aa1c66bbbfa80a9d18ac5e385d3a8b049a288e85decbafdb6e7	ames:9f2de8b891914ce2bed57ef5528c2902367f1790d303740ce75c6f4241bdbc5c	ames:76494b07796c1aa1c66bbbfa80a9d18ac5e385d3a8b049a288e85decbafdb6e7	WBNQDOYYEUMPFS-UHFFFAOYSA-N	CMFNMSMUKZHDEY-UHFFFAOYSA-N	CCN(CC)N=O	O=NOO	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-oxoguanine measurement","L4"]	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-oxoguanine measurement","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=8-hydroxyguanine (8-OHG) measurement", "biological_system=animal model \| Rattus norvegicus \| liver", "canonical_assay_context=8-oxoguanine measurement", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=oxidized_dna_base", "endpoint_name=oxidized_base_measurement", ...	[ "assay_version=8-oxoG measurement (sensitive assay, unspecified format)", "canonical_assay_context=8-oxoguanine measurement", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=oxidized_dna_base", "endpoint_name=oxidized_base_measurement", "endpoint_subtype=8-oxoG", "molecule_rol...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.779023	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-oxoguanine measurement","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"oxidized_base_measurement\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"8-oxog...	0	0	0.982014	0.779023	0.982014	0.017986	safety_canonical_v27	1	true	0.157895	-1	-1	-1	indirect_record	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-oxoguanine measurement","L4"]	WBNQDOYYEUMPFS-UHFFFAOYSA-N	CMFNMSMUKZHDEY-UHFFFAOYSA-N	parent:WBNQDOYYEUMPFS-UHFFFAOYSA-N	parent:CMFNMSMUKZHDEY-UHFFFAOYSA-N	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	1,051	1,044	212	id	train_exact_bucket.v27_safety	identity	{"assay_version":"8-hydroxyguanine (8-OHG) measurement","biological_system":"animal model \| Rattus norvegicus \| liver","canonical_assay_context":"8-oxoguanine measurement","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.4,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"oxidize...	{"assay_version":"8-oxoG measurement (sensitive assay, unspecified format)","biological_system":null,"canonical_assay_context":"8-oxoguanine measurement","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.5,"dose_or_concentration":null,"dose_unit":null,"endpoint_class":"oxidized_dna_base","endpo...	L4	gold_v1	sr_36f59977228f46f59888ee24d63b16ab	sr_4c2c03b8fac74a8c9dabdd9e160c99c5	["premutagenic_damage","oxidized_base_measurement","signed_effect_direction","ames_damage_direction.v1","8-oxoguanine measurement"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>CC1(C)CC(Cl)CN(CCCC[C@@H](C(=O)OCc2ccccc2)N2CC(Cl)CC(C)(C)C2)C1</SMILES> - Assay version: agarose gel electrophoresis of supercoiled plasmid DNA, 1% agarose, 1× TAE - Biological...	(A)	train	86e32a86680c1bf5d86bc7a1bd6b76ff3ac7367914f44d1efc9305cbc07dcc69	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:f139b13a5ae7c6a68470b6aed66b8bd0d1be5b268f5e9767b8d8330932f9cb49	ames:0cda16b6b26ef9fc69a84ed9612554ca1967c217ea007ca6418193f8c221b981	ames:f139b13a5ae7c6a68470b6aed66b8bd0d1be5b268f5e9767b8d8330932f9cb49	ames:0cda16b6b26ef9fc69a84ed9612554ca1967c217ea007ca6418193f8c221b981	PTILDWJVJIEZRG-ABHNRTSZSA-N	QAGILAWDKXYSMJ-VHYCJAOWSA-N	COC(=O)[C@H](CCCCN1CC(Cl)CC(C)(C)C1)N1CC(Cl)CC(C)(C)C1	CC1(C)CC(Cl)CN(CCCC[C@@H](C(=O)OCc2ccccc2)N2CC(Cl)CC(C)(C)C2)C1	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","agarose gel electrophoresis: pBR322 DNA single-strand breaks","L4"]	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","agarose gel electrophoresis: pBR322 DNA single-strand breaks","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=agarose gel electrophoresis of supercoiled plasmid DNA, 1% agarose, 1× TAE", "biological_system=cell-free DNA \| pBR322 supercoiled plasmid (3.5 nM)", "canonical_assay_context=agarose gel electrophoresis: pBR322 DNA single-strand breaks", "canonical_measurement_scale_id=ames_damage_direction.v1"...	[ "assay_version=agarose gel electrophoresis of supercoiled plasmid DNA, 1% agarose, 1× TAE", "biological_system=cell-free DNA \| pBR322 supercoiled plasmid (3.5 nM)", "canonical_assay_context=agarose gel electrophoresis: pBR322 DNA single-strand breaks", "canonical_measurement_scale_id=ames_damage_direction.v1"...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.871523	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","agarose gel electrophoresis: pBR322 DNA single-strand breaks","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"strand_break_physical_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"agar...	0	0	0.982014	0.871523	0.982014	0.017986	safety_canonical_v27	1	true	0.690909	-1	-1	-1	indirect_record	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","agarose gel electrophoresis: pBR322 DNA single-strand breaks","L4"]	PTILDWJVJIEZRG-ABHNRTSZSA-N	QAGILAWDKXYSMJ-VHYCJAOWSA-N	C1CCN(CCCCCN2CCCCC2)CC1	O=C(OCc1ccccc1)C(CCCCN1CCCCC1)N1CCCCC1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	96	94	71	id	train_exact_bucket.v27_safety	identity	{"assay_version":"agarose gel electrophoresis of supercoiled plasmid DNA, 1% agarose, 1\u00d7 TAE","biological_system":"cell-free DNA \| pBR322 supercoiled plasmid (3.5 nM)","canonical_assay_context":"agarose gel electrophoresis: pBR322 DNA single-strand breaks","canonical_measurement_scale_id":"ames_damage_direction.v1...	{"assay_version":"agarose gel electrophoresis of supercoiled plasmid DNA, 1% agarose, 1\u00d7 TAE","biological_system":"cell-free DNA \| pBR322 supercoiled plasmid (3.5 nM)","canonical_assay_context":"agarose gel electrophoresis: pBR322 DNA single-strand breaks","canonical_measurement_scale_id":"ames_damage_direction.v1...	L4	gold_v1	sr_3bb079303b6e4fbda18bda547addb4fc	sr_4b11c9694513407dbada524b316a1008	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","agarose gel electrophoresis: pBR322 DNA single-strand breaks"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>Nc1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@@H]2O)c(=O)n1</SMILES> - Assay version: in vitro NHEJ end-joining assay with rat cerebrum protein extracts, measur...	(B)	train	77977e7d426e124b19fe4b4b8836efb26899aae7580d9ca7bf6c75713eb233fc	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:ea251b0df9c63c73e4b9e46c6762803b2ef9ae9c5168417633b622e26ea6104e	ames:2cb9ad8e3186b7a9574cd1e6c4599cf2357b8b27b09575ffc421a2980c20c7cb	ames:ea251b0df9c63c73e4b9e46c6762803b2ef9ae9c5168417633b622e26ea6104e	ames:2cb9ad8e3186b7a9574cd1e6c4599cf2357b8b27b09575ffc421a2980c20c7cb	IMQLKJBTEOYOSI-UHFFFAOYSA-N	PCDQPRRSZKQHHS-CCXZUQQUSA-N	O=P(O)(O)OC1C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1OP(=O)(O)O	Nc1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@@H]2O)c(=O)n1	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=in vitro end-joining assay (gel-based detection of monomer/dimer/trimer concatamers)", "biological_system=in vitro cell extract \| Homo sapiens \| HeLa AS65 (Ku-depleted)", "canonical_assay_context=cell-free NHEJ end-joining assay", "canonical_measurement_scale_id=ames_damage_direction.v1", "do...	[ "assay_version=in vitro NHEJ end-joining assay with rat cerebrum protein extracts, measuring dimeric and multimeric recombinant NHEJ products", "biological_system=in vitro protein extract \| Rattus norvegicus \| rat cerebrum (brain) protein extracts", "canonical_assay_context=cell-free NHEJ end-joining assay", ...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	2	0	2	0.761028	{ "nontransfer": 0.9999999997892278, "transfer": 2.1077215650052163e-10 }	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"repair_activity_or_kinetics\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"cell...	2	2.628024	0	0.761028	0	1	safety_canonical_v27	0	true	0.166667	-1	-1	-1	indirect_record	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	IMQLKJBTEOYOSI-UHFFFAOYSA-N	PCDQPRRSZKQHHS-CCXZUQQUSA-N	C1CCCCC1	O=c1ncccn1C1CCCO1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	108	104	42	id	train_exact_bucket.v27_safety	identity	{"assay_version":"in vitro end-joining assay (gel-based detection of monomer/dimer/trimer concatamers)","biological_system":"in vitro cell extract \| Homo sapiens \| HeLa AS65 (Ku-depleted)","canonical_assay_context":"cell-free NHEJ end-joining assay","canonical_measurement_scale_id":"ames_damage_direction.v1","confidenc...	{"assay_version":"in vitro NHEJ end-joining assay with rat cerebrum protein extracts, measuring dimeric and multimeric recombinant NHEJ products","biological_system":"in vitro protein extract \| Rattus norvegicus \| rat cerebrum (brain) protein extracts","canonical_assay_context":"cell-free NHEJ end-joining assay","canon...	L4	gold_v1	sr_f2a528ff7ef44e67a4264e0379570332	sr_dd573e81060e422588cde9ba7a1bc5f1	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>O=P(O)(O)OC1C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1OP(=O)(O)O</SMILES> - Assay version: in vitro non-homologous end joining (NHEJ) DNA ligation assay - Biological...	(A)	train	268ed1f30d4deec713fdb7fb68843231b9fdcc13fcdf031f3de7cebf8f33e2c1	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:200e8693afa0a941ac281c60ca522f0fddc4cb9d643fb0bf6f0eb145ab557256	ames:a908b796475580effd87b8fcef2294e18ad1f31e892b0b24f82cd4cd22344929	ames:200e8693afa0a941ac281c60ca522f0fddc4cb9d643fb0bf6f0eb145ab557256	ames:a908b796475580effd87b8fcef2294e18ad1f31e892b0b24f82cd4cd22344929	IMQLKJBTEOYOSI-GPIVLXJGSA-N	IMQLKJBTEOYOSI-UHFFFAOYSA-N	O=P(O)(O)O[C@H]1[C@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@H]1OP(=O)(O)O	O=P(O)(O)OC1C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1OP(=O)(O)O	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=In vitro NHEJ end-joining assay with cell-free HeLa extract (PC-C phosphocellulose fraction)", "biological_system=cell-free extract \| Homo sapiens \| HeLa extract, PC-C fraction containing DNA-PK and XRCC4/DNA ligase IV", "canonical_assay_context=cell-free NHEJ end-joining assay", "canonical_mea...	[ "assay_version=in vitro non-homologous end joining (NHEJ) DNA ligation assay", "biological_system=in vitro biochemical ligation reaction \| Homo sapiens \| human cell extracts and recombinant NHEJ factors (Ku, DNA-PKcs, XRCC4, XLF, Ligase IV)", "canonical_assay_context=cell-free NHEJ end-joining assay", "canoni...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.761028	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"repair_activity_or_kinetics\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"cell...	0	0	0.982014	0.761028	0.982014	0.017986	safety_canonical_v27	1	true	1	-1	-1	-1	indirect_record	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay","L4"]	IMQLKJBTEOYOSI-GPIVLXJGSA-N	IMQLKJBTEOYOSI-UHFFFAOYSA-N	C1CCCCC1	C1CCCCC1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	108	104	42	id	train_exact_bucket.v27_safety	identity	{"assay_version":"In vitro NHEJ end-joining assay with cell-free HeLa extract (PC-C phosphocellulose fraction)","biological_system":"cell-free extract \| Homo sapiens \| HeLa extract, PC-C fraction containing DNA-PK and XRCC4/DNA ligase IV","canonical_assay_context":"cell-free NHEJ end-joining assay","canonical_measureme...	{"assay_version":"in vitro non-homologous end joining (NHEJ) DNA ligation assay","biological_system":"in vitro biochemical ligation reaction \| Homo sapiens \| human cell extracts and recombinant NHEJ factors (Ku, DNA-PKcs, XRCC4, XLF, Ligase IV)","canonical_assay_context":"cell-free NHEJ end-joining assay","canonical_me...	L4	gold_v1	sr_dfa3f8d322274870af999acb3b9040ca	sr_660eb319d2f64c12b305d45c70106a01	["premutagenic_damage","repair_activity_or_kinetics","signed_effect_direction","ames_damage_direction.v1","cell-free NHEJ end-joining assay"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>O=C(O)C(Cl)Cl</SMILES> - Assay version: neutral comet assay - Biological system: in vitro cells \| Homo sapiens \| A549 and H1299 NSCLC cells - Canonical assay context: neutral co...	(B)	train	f55d0d3cd734c905248f26fa3db6df3a51fcaee7015ea47536f28617f79e4be1	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:68653d058680b86eba0759779b49bd19ed402d91249db0cd1ad408871eaacb4b	ames:4b8cf35f180e4d6ffa0ba6e4b1b434c2de21c260051ec4fde367d9280dd4d92e	ames:68653d058680b86eba0759779b49bd19ed402d91249db0cd1ad408871eaacb4b	ames:4b8cf35f180e4d6ffa0ba6e4b1b434c2de21c260051ec4fde367d9280dd4d92e	JVTAAEKCZFNVCJ-UWTATZPHSA-N	JXTHNDFMNIQAHM-UHFFFAOYSA-N	C[C@@H](O)C(=O)O	O=C(O)C(Cl)Cl	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","neutral comet assay (Olive tail moment)","L4"]	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","neutral comet assay (Olive tail moment)","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=neutral comet assay (Olive tail moment)", "biological_system=in vitro cells \| Homo sapiens \| HeLa", "canonical_assay_context=neutral comet assay (Olive tail moment)", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=20", "dose_unit=mM", "endpoint_class=str...	[ "assay_version=neutral comet assay", "biological_system=in vitro cells \| Homo sapiens \| A549 and H1299 NSCLC cells", "canonical_assay_context=neutral comet assay (Olive tail moment)", "canonical_measurement_scale_id=ames_damage_direction.v1", "dose_or_concentration=50", "dose_unit=mM", "endpoint_class=s...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	far	0	2	2	0.929605	{ "nontransfer": 0.9999999752519989, "transfer": 2.4748001099174298e-8 }	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","neutral comet assay (Olive tail moment)","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"comet_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"neutral comet assay ...	2	2.151452	0	0.929605	0	1	safety_canonical_v27	0	true	0.4	-1	-1	-1	indirect_record	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","neutral comet assay (Olive tail moment)","L4"]	JVTAAEKCZFNVCJ-UWTATZPHSA-N	JXTHNDFMNIQAHM-UHFFFAOYSA-N	parent:JVTAAEKCZFNVCJ-UWTATZPHSA-N	parent:JXTHNDFMNIQAHM-UHFFFAOYSA-N	{ "aggregation_method": "individual_record", "display_measurement_text": "-1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 0, "aggregate_max": 0, "aggregate_q1": 0, "...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	44	44	27	id	train_exact_bucket.v27_safety	identity	{"assay_version":"neutral comet assay (Olive tail moment)","biological_system":"in vitro cells \| Homo sapiens \| HeLa","canonical_assay_context":"neutral comet assay (Olive tail moment)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.8,"dose_or_concentration":"20","dose_unit":"mM","endpoint_c...	{"assay_version":"neutral comet assay","biological_system":"in vitro cells \| Homo sapiens \| A549 and H1299 NSCLC cells","canonical_assay_context":"neutral comet assay (Olive tail moment)","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.85,"dose_or_concentration":"50","dose_unit":"mM","endpoin...	L4	gold_v1	sr_4a5091884c3d48bb80d0f40f789bdb92	sr_fdb5950aafc64ef8ba6128d6071d8625	["premutagenic_damage","comet_assay","signed_effect_direction","ames_damage_direction.v1","neutral comet assay (Olive tail moment)"]
You are comparing two experiments selected from similar assays. The experimental details may differ. Experiment A (known measurement) <SMILES>O=C(O)C[C@@H]1C(=O)O[C@H]2[C@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H](OC(=O)c1cc(O)c(O)c(O)c1)O[C@@H]2COC(=O)c1cc(O)c(O)c(O)c1</SMILES>...	(A)	train	7aefaad7212bd1d0095eca38b18310548d97dd4083ae0c757046a1066b704dae	-1	null	-1	null	null	null	ames	premutagenic_damage	limited_balanced_parent_morgan_first.v28_safety	ames:b23a2cb6d85e9fcd71ce4f0135de0fe7c84b894541ec5c906baa2bcaa707d6bb	ames:c0b1d3890e35cdc0dc7a1878cd4daa626db0fbb87052e03d90d75cc224510962	ames:b23a2cb6d85e9fcd71ce4f0135de0fe7c84b894541ec5c906baa2bcaa707d6bb	ames:c0b1d3890e35cdc0dc7a1878cd4daa626db0fbb87052e03d90d75cc224510962	JPUKWEQWGBDDQB-QSOFNFLRSA-N	YGVHOSGNOYKRIH-FJPMMHPYSA-N	O=c1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12	O=C(O)C[C@@H]1C(=O)O[C@H]2[C@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H](OC(=O)c1cc(O)c(O)c(O)c1)O[C@@H]2COC(=O)c1cc(O)c(O)c(O)c1	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","plasmid DNA strand break assay by relaxation","L4"]	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","plasmid DNA strand break assay by relaxation","L4"]	exact_v10_pair_bucket_and_level	exact_v10_pair_bucket_and_level	[ "assay_version=agarose gel electrophoresis of supercoiled plasmid DNA, conversion of supercoiled to relaxed (open circular) form", "biological_system=cell-free DNA \| plasmid DNA", "canonical_assay_context=plasmid DNA strand break assay by relaxation", "canonical_measurement_scale_id=ames_damage_direction.v1",...	[ "assay_version=agarose gel plasmid relaxation/supercoiled DNA strand break assay", "biological_system=cell-free DNA \| pBR322 plasmid DNA", "canonical_assay_context=plasmid DNA strand break assay by relaxation", "canonical_measurement_scale_id=ames_damage_direction.v1", "endpoint_class=strand_break_or_alkali...	same_exact_v10_pair_bucket_and_level	1	1	null	null	null	null	near	2	2	0	0.831473	{ "nontransfer": 0.01798620996209155, "transfer": 0.9820137900379085 }	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","plasmid DNA strand break assay by relaxation","L4"]	L4	ordinal	{ "calibration_sha256": "cda42c40187d956b35ca08a07df64c8513da784050e7d10bfde7c2c73e64b065", "groups": { "assay_concept": "L4", "measurement_kind": "ordinal", "query_condition_group": "[\"premutagenic_damage\",\"strand_break_physical_assay\",\"signed_effect_direction\",\"ames_damage_direction.v1\",\"plas...	0	0	0.982014	0.831473	0.982014	0.017986	safety_canonical_v27	1	true	0.165049	-1	-1	-1	indirect_record	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","plasmid DNA strand break assay by relaxation","L4"]	JPUKWEQWGBDDQB-QSOFNFLRSA-N	YGVHOSGNOYKRIH-FJPMMHPYSA-N	O=c1c(OC2CCCCO2)c(-c2ccccc2)oc2ccccc12	O=C1CC2CC(=O)OC3C(COC(=O)c4ccccc4)OC(OC(=O)c4ccccc4)C(OC(=O)c4cccc(c42)O1)C3OC(=O)c1ccccc1	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	{ "aggregation_method": "individual_record", "display_measurement_text": "1", "display_unit_text": "signed_effect_direction", "display_transform_id": "canonical_stage3.v10", "source_record_count": 1, "deduplicated_source_record_count": 1, "aggregate_min": 2, "aggregate_max": 2, "aggregate_q1": 2, "a...	71	71	55	id	train_exact_bucket.v27_safety	identity	{"assay_version":"agarose gel electrophoresis of supercoiled plasmid DNA, conversion of supercoiled to relaxed (open circular) form","biological_system":"cell-free DNA \| plasmid DNA","canonical_assay_context":"plasmid DNA strand break assay by relaxation","canonical_measurement_scale_id":"ames_damage_direction.v1","con...	{"assay_version":"agarose gel plasmid relaxation/supercoiled DNA strand break assay","biological_system":"cell-free DNA \| pBR322 plasmid DNA","canonical_assay_context":"plasmid DNA strand break assay by relaxation","canonical_measurement_scale_id":"ames_damage_direction.v1","confidence":0.8,"dose_or_concentration":null...	L4	gold_v1	sr_5bbac711f70e49b5b74e16aad1bdd585	sr_4b4a3869d8b744dabba60642122381ef	["premutagenic_damage","strand_break_physical_assay","signed_effect_direction","ames_damage_direction.v1","plasmid DNA strand break assay by relaxation"]

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Ames record-level V27 L4

This level-specific release uses current V10 physical evidence, the active Gold-owned level mapping, and Gold-v1 parent-disjoint evaluation. Undefined variance ratios are allowed; defined ratios above 0.65 are excluded. Prompts display canonical Stage-3 measurement and unit pairs.

Rows: {'train': 24758, 'validation_ranking': 23347, 'test_ranking': 22663}

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