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22099523 | Plasma pro-endothelin-1 and respiratory distress in newborn infants. | Plasma concentrations of the stable endothelin-1 precursor, C-terminal portion of the endothelin-1 precursor, determined prospectively in 293 newborn infants (gestational age, 24-41 weeks) at birth and on day 3 of life were unrelated to gestational age at birth, but strongly associated with respiratory distress when me... |
22099521 | Drug susceptibility testing and pharmacokinetics question current treatment regimens in Mycobacterium simiae complex disease. | The Mycobacterium plex bacteria can cause opportunistic infections in humans. In the case of definite disease, there are no evidence-based treatment regimens and es are very disappointing. To increase the evidence base underpinning treatment regimens for M. plex disease, drug susceptibility patterns and rifampicin/etha... |
22099522 | Neurodevelopmental outcomes in infants requiring resuscitation in developing countries. | To determine whether resuscitation of infants who failed to develop effective breathing at birth increases survivors with neurodevelopmental impairment. |
22099524 | 3 T MRI of hepatocellular carcinomas in patients with cirrhosis: does T2-weighted imaging provide added value? | To assess whether T2-weighted imaging (T2WI) provides any added value for the detection of hepatocellular carcinoma (HCC) in patients with cirrhosis, especially for lesions smaller than 2 cm. |
22099525 | A longitudinal study on the effects of maternal smoking and secondhand smoke exposure during pregnancy on neonatal neurobehavior. | Maternal smoking during pregnancy is one of the most modifiable causes of morbidity and mortality for both pregnant women and their fetuses. The long-term effects of prenatal exposure to smoke on child behavior and development have been the subject of more extensive research than have the short-term effects. Therefore,... |
22099526 | Cognitive and adaptive development of patients with tuberous sclerosis complex: a retrospective, longitudinal investigation. | The aim of the work described here was to systematically analyze the developmental trajectory of patients with tuberous plex (TSC). |
22099527 | Cortical thickness abnormalities associated with depressive symptoms in temporal lobe epilepsy. | Depression in patients with temporal lobe epilepsy (TLE) is highly prevalent and carries significant morbidity and mortality. Its neural basis is poorly understood. We used quantitative, surface-based MRI analysis to correlate brain morphometry with severity of depressive symptoms in 38 patients with TLE and 45 control... |
22099528 | Perceived benefits of sharing health data between people with epilepsy on an online platform. | An munity was developed on to share data between patients to improve their es by finding other patients like them. In a 14-day response period, 221 patients with epilepsy (mean age: 40 years, SD: 12, range: 17-72, 66% pleted a survey about benefits they perceived. Prior to using the site, a third of respondents (30%) ... |
22099529 | Unmet needs in patients with first-episode schizophrenia: a longitudinal perspective. | This study aimed to identify the course of unmet needs by patients with a first episode of schizophrenia and to determine associated variables. |
22099530 | Wound healing in pre-tibial injuries--an observation study. | Pre-tibial lacerations plex wounds affecting a primarily aged population, with poor healing and a potentially significant impact on social well-being. Management of these wounds has changed little in 20 years, despite significant advances in wound care. A retrospective observational study was undertaken to observe curr... |
22099531 | Xanthine oxidase inhibition for the treatment of cardiovascular disease: a systematic review and meta-analysis. | Xanthine oxidase inhibition (XOI) reduces oxidative stress in the vasculature. Moreover it reduces uric acid levels, a risk factor for the development of cardiovascular disease. As such, XOI holds a potentially dual mechanism for the treatment of cardiovascular disease. |
22099532 | Fracture strength of incisor crowns after intracoronal bleaching with sodium percarbonate. | pare the fracture resistance of bovine teeth after intracoronal bleaching with sodium percarbonate (SPC) or sodium perborate (SP) mixed with water or 20% hydrogen peroxide (HP). |
22099533 | Mitochondrial complex I deficiency of nuclear origin II. Non-structural genes. | Complex I deficiency is the most frequent cause of respiratory chain diseases. This large plex posed in human of 45 structural subunits, of which 7 are mitochondrial-encoded and 38 are nuclear-encoded. Most of the pathological mutations responsible plex I deficiencies have been identified to date plex I structural subu... |
22099536 | Physiological responses of Egeriadensa to high ammonium concentration and nitrogen deficiency. | High ammonia (i.e. the total of NH(3) and NH(4)(+)) concentration or nitrogen deficiency in water can exert stress on growth and health of many aquatic plants. To investigate the physiological impacts of high ammonia-N (NH(4)Cl) concentration and nitrogen deficiency on plant physiology, apical shoots of submerged macro... |
22099535 | The effect of the hormonal milieu of pregnancy on deep infiltrating endometriosis: serial ultrasound assessment of changes in size and pattern of deep endometriotic lesions. | Deep infiltrating endometriosis (DIE) is associated with severe painful symptoms and represents plex management challenge. |
22099537 | Levels of organochlorine pesticides and polychlorinated biphenyls in the critically endangered Iberian lynx and other sympatric carnivores in Spain. | Accumulation of pounds is well studied in aquatic food chains whereas little information is available from terrestrial food chains. This study presents data of organochlorine levels in tissue and plasma samples of 15 critically endangered Iberian lynx (Lynx pardinus) and other 55 wild carnivores belonging to five speci... |
22099538 | Metal (Cu, Cd and Zn) removal and stabilization during multiple soil washing by saponin. | The influence of multiple saponin washing on copper, cadmium and zinc removal and stability in three types of soils (loamy sand, loam, silty clay) was investigated. Distribution of metals and their mobility measured as the ratio of exchangeable form to the sum of all fractions in soils was differential. After single wa... |
22099539 | Zinc tolerance and accumulation in the salt-marsh shrub Halimione portulacoides. | The halophytic shrub Halimione portulacoides is known to be capable of growth in soils containing extremely high concentrations of Zn. This study evaluated in detail the tolerance and accumulation potential of H. portulacoides under moderate and high external Zn levels. A greenhouse experiment was conducted in order to... |
22099540 | Lactate oxidation in pyrite suspension: a Fenton-like process in situ generating H2O2. | Pyrite is mon mineral at many mining sites. In this study, the mineral pyrite was studied as a Fenton-like reagent for environmental concerns. We selected lactate as a model target molecule to evaluate the Fenton-like catalytic efficiency of pyrite upon organic oxidation. plete set of control experiments in both aerobi... |
22099542 | Inconvenience due to travelers' diarrhea: a prospective follow-up study. | Limited data exist documenting the degree to which travelers are inconvenienced by travelers' diarrhea (TD). We performed a prospective follow-up study at the travel clinic of Leiden University Medical Center in The Netherlands to determine the degree of inconvenience and to determine how experiencing TD affects travel... |
22099543 | A claw is like my hand: comparison supports goal analysis in infants. | Understanding the intentional relations in others' actions is critical to human social life. Origins of this knowledge exist in the first year and are a function of both acting as an intentional agent and observing movement cues in actions. We explore a new mechanism we believe plays an important role in infants' under... |
22099544 | Relatively certain! Comparative thinking reduces uncertainty. | Comparison is one of the most ubiquitous and versatile mechanisms in human information processing. Previous research demonstrates that one consequence parative thinking is increased judgmental parison allows for quicker judgments without a loss in accuracy. We hypothesised that a second potential consequence parative t... |
22099546 | Recurrent Ochrobactrum anthropi and Shewanella putrefaciens bloodstream infection complicating hemodialysis. | Bloodstream infections (BSIs) mon in hemodialysis, especially when the access is a catheter. These infections are monly gram-positive bacteria or gram-negative bacilli and on some occasions, fungi. Ochrobactrum anthropi and Shewanella putrefaciens are ubiquitous hydrophilic gram-negative bacilli. There have been three ... |
22099547 | Estimating the cost-effectiveness of lifestyle intervention programmes to prevent diabetes based on an example from Germany: Markov modelling. | Type 2 diabetes mellitus (T2D) poses a large worldwide burden for health care systems. One possible tool to decrease this burden is primary prevention. As it is unethical to wait until perfect data are available to conclude whether T2D primary prevention intervention programmes are cost-effective, we need a model that ... |
22099548 | Imaging mass spectrometry evaluation of the effects of various irrigation fluids in a rat model of postoperative cerebral edema. | Using imaging mass spectrometry (IMS), we investigated the cerebral protective effect of an artificial cerebrospinal fluid (CSF), ARTCEREB (Artcereb, Otsuka Pharmaceutical Factory, Inc., Tokushima, Japan), as an irrigation and perfusion solution for neurosurgical procedures in a rat craniotomy model. |
22099559 | Outpatient-based scalp surgery without shaving and allowing use of shampoo. | To assess the authors' experience of wound management following scalp mass surgery after introducing a policy of leaving hair unshaved and allowing patients to use shampoo. |
22099560 | Temporary occlusion test using a microcatheter. | The balloon occlusion test (BOT) is a well-accepted technique for the treatment of large plex aneurysms. However, this procedure may not be feasible for small arteries such as the posterior inferior cerebellar artery (PICA). We report our experience with endovascular treatment of a fusiform PICA aneurysm employing a mi... |
22099561 | Direct percutaneous puncture approach versus surgical cutdown technique for intracranial neuroendovascular procedures: technical aspects. | To present the authors' experience with a direct transcervical or transbrachial puncture approach in neuroendovascular procedures in which cranial access via monly used percutaneous transfemoral route was impossible because of tortuous upstream angioarchitecture. |
22099563 | Use of multimedia messaging system (MMS) by junior doctors for scan image transmission in neurosurgery. | Multimedia Messaging Service (MMS) is used by neurosurgical residents to transmit scan images to the attending neurosurgeon in conjunction with telephone consultation. This service has been well received by the attending neurosurgeons, who felt that after viewing scan images on their phones, they felt increased confide... |
22099566 | A systematic review of instruments to measure depressive symptoms in patients with schizophrenia. | Depressive symptoms require accurate recognition and monitoring in clinical practice of patients with schizophrenia. Depression instruments developed for use in depressed patients may not discriminate depressive symptoms from negative psychotic symptoms. |
22099565 | How large is the typical subarachnoid hemorrhage? A review of current neurosurgical knowledge. | Despite the morbidity and mortality of subarachnoid hemorrhage (SAH), the average volume of a typical hemorrhage is not well defined. Animal models of SAH often do not accurately mimic the human disease process. |
22099570 | Use of real-time ultrasound guidance for the placement of hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials. | Insertion of percutaneous hemodialysis catheters is an invasive procedure with a small but definite risk of morbidity and mortality. |
22099581 | Neither bipolar nor obsessive-compulsive disorder: compulsive buyers are impulsive acquirers. | Compulsive buying (CB) is currently classified as an impulse control disorder (ICD) not otherwise classified. Compulsive buying prevalence is estimated at around 5% of the general population. There is controversy about whether CB should be classified as an ICD, a subsyndromal bipolar disorder (BD), or an pulsive disord... |
22099582 | Building capacity in mental health interventions in low resource countries: an apprenticeship model for training local providers. | Recent global mental health research suggests that mental health interventions can be adapted for use across cultures and in low resource environments. As evidence for the feasibility and effectiveness of certain specific interventions begins to accumulate, guidelines are needed for how to train, supervise, and ideally... |
22099583 | A review of factors that affect mortality following colectomy. | The tightening focus on optimizing surgical es has pushed tracking perioperative mortality to the forefront of interest. The goal of this study is to analyze factors affecting mortality after colorectal resection at a single tertiary care center. |
22099584 | Multiple kinase pathways involved in the different de novo sensitivity of pancreatic cancer cell lines to 17-AAG. | 17-Allylamino-17-demethoxygeldanamycin (17-AAG) specifically targets heat shock protein (HSP)90 and inhibits its chaperoning functions for multiple kinases involved in cancer cell growth and survival. To select responsive patients, the molecular mechanisms underlying the sensitivity of cancer cells to 17-AAG must be el... |
22099585 | Comparison of different thoracic trauma scoring systems in regards to prediction of post-traumatic complications and outcome in blunt chest trauma. | As accurate assessment of thoracic injury severity in the early phase after trauma is difficult, pared different thoracic trauma scores regarding their predictive ability for the development of plications and mortality. |
22099586 | Nonlinear mechanical behavior of the human common, external, and internal carotid arteries in vivo. | The mechanical environment and properties of the carotid artery play an important role in the formation and progression of atherosclerosis in the carotid bifurcation. The purpose of this work was to measure pare the range and variation of circumferential stress and tangent elastic moduli in the mon (CCA), external (ECA... |
22099590 | Comparative analysis of histopathologic effects of synthetic meshes based on material, weight, and pore size in mice. | While synthetic prosthetics have essentially e mandatory for hernia repair, mesh-induced chronic inflammation and scarring can lead to chronic pain and limited mobility. Mesh propensity to induce such adverse effects is likely related to the prosthetic's material, weight, and/or pore size. We aimed pare histopathologic... |
22099592 | Use of autologous chondrocytes and bioinert perforated chambers to tissue engineer cartilage in vivo. | To explore the potential applications of a chamber for in vivo tissue engineering, and to establish a novel model for in vivo tissue-engineered cartilage. |
22099594 | Excorporeal normothermic machine perfusion resuscitates pig DCD livers with extended warm ischemia. | The shortage in donor livers has led to increased use of allografts derived from donation after cardiac death (DCD). promised viability in these livers leads to inferior post-transplantation allograft function and pared with donation after brain death (DBD) donor grafts. In this study, we reconditioned DCD livers using... |
22099593 | Dynamics of short-term gene expression profiling in liver following thermal injury. | Severe trauma, including burns, triggers a systemic response that significantly impacts on the liver, which plays a key role in the metabolic and immune responses aimed at restoring homeostasis. While many of these changes are likely regulated at the gene expression level, there is a need to better understand the dynam... |
22099595 | Use of decellularized porcine liver for engineering humanized liver organ. | New bioartificial liver devices are needed to supplement the limited supply of organ donors available for patients with end-stage liver disease. Here, we report the results of a pilot study aimed at developing a humanized porcine liver by transplanting second trimester human fetal hepatocytes (Hfh) co-cultured with fet... |
22099596 | The use of cognitive task analysis to improve instructional descriptions of procedures. | Surgical training relies heavily on the ability of expert surgeons to plete and accurate descriptions of plex procedure. However, research from a variety of domains suggests that experts often omit critical information about the judgments, analysis, and decisions they make when solving a difficult problem or performing... |
22099598 | Decreased expression of hepatic signaling phosphoproteins after laparoscopic and hand-assisted surgery in a porcine model. | Minimally-invasive surgery (MIS) is associated with a decreased activation of both systemic and peritoneal pared with the open technique. However, hepatic response to laparoscopic (LAP) and hand-assisted laparoscopic (HAL) surgery has not been defined well. We postulated that both LAP and HAL approaches are associated ... |
22099597 | Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression. | Pancreatic adenocarcinoma remains among the most lethal of human malignancies. Overall 5-y survival is less than 5%, and only 20% of patients presenting with localized disease amenable to surgical resection. Even in patients who undergo resection, long-term survival remains extremely poor. A major contributor to the ag... |
22099599 | The effect of diabetes and poor left ventricular function on bone marrow cell-induced myocardial protection. | The myocardium of patients with diabetes and poor left ventricular (LV) function cannot be protected by interventions such as ischemic preconditioning (IP). We investigated whether these clinical conditions influence the protection elicited by the paracrine effect of bone marrow cells (BMCs) and whether the cause for l... |
22099600 | The role of oxidative stress response revealed in preconditioning heat stimulation in skeletal muscle of rats. | Our previous study showed that preconditioned local somatothermal stimulation (LSTS) protected subsequent ischemia-reperfusion injury of the skeletal muscle. The exact mechanisms of LSTS preconditioning remain unknown. The aim of this study was to test the hypothesis stating that heat stimulation induces free radical p... |
22099602 | Up-regulated expression of MIF by interfacial membrane fibroblasts and macrophages around aseptically loosened implants. | Local chronic inflammatory reaction plays an important role in the process of aseptic loosening of implants after total joint replacement. In addition, macrophage migration inhibitory factor (MIF) is a key upstream regulator of inflammation, and it is a significant regulator of inflammatory diseases. The purpose of thi... |
22099603 | Removal of 17 cytokines, HMGB1, and albumin by continuous hemofiltration using a cellulose triacetate membrane: an ex vivo study. | Hemofiltration is often used to treat critically ill patients with renal failure and septic shock. Although hemofiltration has been reported to remove humoral mediators such as cytokines, most studies have investigated the removal of only limited kinds of cytokines. Here, we assessed the removal of 17 cytokines, HMGB1,... |
22099601 | The role of estrogen receptor α and β in regulating vascular smooth muscle cell proliferation is based on sex. | We previously demonstrated that vascular smooth muscle cells (VSMC) proliferation and development of neointimal hyperplasia as well as the ability of nitric oxide (NO) to inhibit these processes is dependent on sex and hormone status. The aim of this study was to evaluate the role of estrogen receptor (ER) in mediating... |
22099604 | Changing epidemiology of acute appendicitis in the United States: study period 1993-2008. | Addis et al. [5] described the epidemiology of appendicitis in the United States from 1970 to 1984. He reported that while overall incidence decreased, the highest incidence of appendicitis occurred in 10- to 19-y-olds. This study examines if the incidence of appendicitis and mean age of diagnosis has changed, and whet... |
22099605 | Pterostilbene and cancer: current review. | Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is an antioxidant that is primarily found in blueberries. Studies suggest that pterostilbene exhibits the hallmark characteristics of an effective anticancer agent based on its antineoplastic properties in mon malignancies. In vitro models have shown that pterostilb... |
22099607 | Severe and anxious depression: combining definitions of clinical sub-types to identify patients differentially responsive to selective serotonin reuptake inhibitors. | Patients with severe major depressive disorder are more likely than those with mild/moderate depression to experience the relative benefits of antidepressant therapy versus placebo. Several studies have, unexpectedly, failed to show a similar antidepressant-placebo discrepancy between patients with versus without anxio... |
22099606 | Abnormal anterior cingulate cortical activity during emotional n-back task performance distinguishes bipolar from unipolar depressed females. | Depression in the context of bipolar disorder (BDd) is often misdiagnosed as unipolar disorder depression (UDd) leading to poor clinical es for many bipolar sufferers. We examined neural circuitry supporting emotion regulation in females with either BDd or UDd as a first stage toward identifying biomarkers that may dif... |
22099608 | Physical activity and function in adolescents with chronic pain: a controlled study using actigraphy. | Physical functioning is often impaired in adolescents with chronic pain, which has largely been demonstrated through subjective self-report measures. Actigraphy uses motion monitoring as an objective means for assessing one dimension of physical functioning; physical activity level. This study used subjective and objec... |
22099609 | Kyphectomy for congenital kyphosis due to meningomyelocele: a case treated with a modified approach to skin healing. | This study is a case report of a meningomyelocele patient with congenital kyphosis who was treated with kyphectomy and a special approach to soft tissue healing. The objective of this study is to show a step by step approach to surgical treatment and postoperative care of a meningomyelocele patient with congenital kyph... |
22099610 | Performance characteristics of computed tomography in detecting lymph node metastases in contemporary patients with prostate cancer treated with extended pelvic lymph node dissection. | Computed tomography (CT) is monly used noninvasive procedure for prostate cancer (PCa) staging. All previous studies addressing the ability of CT scan to predict lymph node invasion (LNI) were based on historical patients treated with limited pelvic lymph node dissection (PLND). |
22099612 | Chronic rhinosinusitis. | This article defines chronic rhinosinusitis (CRS) and shares contemporary principles for its diagnosis and management, focusing on practical considerations for rhinoplasty surgeons. Nasal obstruction, the mon symptom of CRS, is frequently the plaint of patients seeking functional rhinoplasty surgery. Because correcting... |
22099613 | Allergic rhinitis. | Familiarity with the diagnosis and management of allergic rhinitis is important for physicians concerned with the nasal airway. Allergic rhinitis is mon and manageable condition that may cause persistent or intermittent symptoms that vary as to duration and severity. Allergic rhinitis impairs quality of life, sleep, sc... |
22099616 | Concurrent rhinoplasty and endoscopic sinus surgery: a review of the pros and cons and a template for success. | Historically concurrent FESS/rhinoplasty was avoided due to concerns of increased risk plication. Recent studies have shown that FESS/rhinoplasty can be performed simultaneously with good es and no significant increase plications. A thorough and effective approach to the patient with sinonasal obstruction requires atte... |
22099614 | Nonallergic rhinitis. | This article reviews a uniform way to describe nonallergic rhinitis in its various forms. The insights into its pathophysiology are briefly reviewed. A classification scheme for the different forms is provided. This is followed by descriptions of the diagnosis, evaluation, and management of nonallergic rhinitis. |
22099615 | Allergic skin disease. | The two mon allergic skin diseases in the world are often the least familiar to practicing surgeons: atopic dermatitis and contact dermatitis. When unrecognized, these disorders can cause great fort and decreased quality of life. This is only made worse by a surgical procedure which can exacerbate the disease process. ... |
22099617 | The unified airway. | The upper and lower respiratory tracts function as an interdependent physiologic mechanism, and stimuli that trigger pathophysiologic changes in one portion of the airway can provoke similar changes throughout the airway. The unified airway model acknowledges these shared airway features, suggesting the importance preh... |
22099611 | Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer. | We have recently witnessed a rapid increase in the number of effective systemic agents for men with metastatic castration-resistant prostate cancer (CRPC), including novel hormonal therapies (abiraterone acetate and MDV3100), immunotherapies (sipuleucel-T), chemotherapies (cabazitaxel), and bone microenvironment target... |
22099618 | Pharmacotherapy of rhinitis and rhinosinusitis. | Concerns for the cosmetic surgeon regarding allergic rhinoconjunctivitis and rhinosinusitis include diagnosis, treatment, and assessment of the disease and whether or not the timing or e of cosmetic procedures will be affected. In this article, the pharmacotherapy of allergic and nonallergic rhinoconjunctivitis and rhi... |
22099619 | The role of alternative medicine in rhinology. | Complementary and alternative medicine (CAM) includes treatments from traditional Chinese medicine, homeopathy, naturopathy, herbal medicine, Ayurvedic medicine, mind-body medicine, chiropractic or osteopathic manipulations, and massage. More than 40% of patients in the United States use CAM, with 17% of CAM use relate... |
22099620 | Sinonasal problems and reflux. | Extraesophageal reflux has been implicated in many disorders affecting the upper airway. This article reviews the recent literature regarding the relationship of refractory chronic rhinosinusitis with extraesophageal reflux. Recent studies have shown that patients with refractory chronic rhinosinusitis have an increase... |
22099622 | Smell and taste disorders. | Olfaction and taste promote satisfaction and protection in daily life. The astute facial plastic surgeon recognizes the importance of a baseline smell test to document the patients' olfactory status before surgery. After surgery, the surgeon must be alert to the possible mechanisms of hyposmia and anosmia and the perti... |
22099621 | Bacteriology and antibiotic resistance in chronic rhinosinusitis. | Chronic rhinosinusitis (CRS) is a prevalent health care problem that may monly encountered in patients desiring aesthetic or reconstructive rhinoplasty. The purpose of this article is to review mon bacterial pathogens associated with CRS, as well as patterns of bacterial resistance in this patient subset. Close underst... |
22099624 | Root trauma and tooth loss through the application of pre-drilled transgingival fixation screws. | Transgingival fixation screws are used for intermaxillary fixation in different situations. The aim of this study was to evaluate the risk of root trauma and tooth loss using pre-drilled transgingival fixation screws. |
22099625 | Acute effects of nicardipine and esmolol on the cardiac cycle, intracardiac hemodynamic and endothelial shear stress in patients with unstable angina pectoris and moderate coronary stenosis: results from single center, randomized study. | This study aimed pare the acute effects of nicardipine and esmolol on hemodynamic and endothelial shear stress (ESS) in patients with unstable angina (UA) and moderate coronary stenosis (MCS). |
22099626 | Comminuted mandibular fracture in child victim of dog bite. | Dog bites represent monly found in Hospital Emergency Clinic. This type of lesion may cause severe harm to patients, but it rarely affects the underlying bone structure causes facial fracture. This study aims to illustrate a rare clinical case in which a pediatric patient presented minuted fracture in the mandible whic... |
22099627 | Plasma BNP, a useful marker of fluid overload in hospitalized hemodialysis patients. | Hospitalization for intercurrent illness frequently disrupts the nutritional status of hemodialysis (HD) patients and jeopardizes the dry weight prescription. We report in this study the evolution of brain natriuretic peptide (BNP), blood pressure and body weight in hospitalized patients and the relationship between BN... |
22099629 | Tracing the evolution of the mitochondrial protein import machinery. | Mitochondria are eukaryotic organelles originated from a single bacterial endosymbiosis about 2 billion years ago. One of the earliest events in the evolution of mitochondria was the acquisition of a mechanism that facilitated the import of proteins from cytosol. The mitochondrial protein import machinery consists of d... |
22099628 | Identification of virtual signal transducers and activators of transcription response elements in the human insulin receptor gene promoter. | In this study, we look for the existence of signal transducers and activators of transcription response elements (STATREs) in the human insulin receptor (hIR) gene promoter and their possible relation with the estradiol-provoked transcriptional repression of the hIR gene and cellular insulin resistance in U-937 human p... |
22099630 | New insights on gene regulation in archaea. | Archaea represent an important and vast domain of life. This cellular domain includes a large diversity of organisms characterized as prokaryotes with basal transcriptional machinery similar to eukarya. In this work we explore the most recent findings concerning the transcriptional regulatory organization in archaeal g... |
22099631 | A generalized graph-theoretical matrix of heterosystems and its application to the VMV procedure. | The extensions of generalized (molecular) graph-theoretical matrix and vector-matrix-vector procedure are considered. The elements of the generalized matrix are redefined in order to describe molecules containing heteroatoms and multiple bonds. The adjacency, distance, detour and reciprocal distance matrices of heteros... |
22099632 | Kernel-based data fusion improves the drug-protein interaction prediction. | Proteins are involved in almost every action of every organism by interacting with other small molecules including drugs. Computationally predicting the drug-protein interactions is particularly important in speeding up the process of developing novel drugs. To borrow the information from existing drug-protein interact... |
22099633 | Analysis and recognition of the GAGA transcription factor binding sites in Drosophila genes. | The transcription factor GAGA, encoded by the gene Trl, controls expression of many Drosophila melanogaster genes. We piled the presently largest sample (120 sites) of published nucleotide sequences with experimentally confirmed binding to GAGA protein. Analysis of the sample has demonstrated that despite an apparent s... |
22099634 | Detecting breakdown points in metabolic networks. | plex network of biochemical reactions present in an organism generates various biological moieties necessary for its survival. It is seen that biological systems are robust to genetic and environmental changes at all levels of organization. Functions of various organisms are sustained against mutational changes by usin... |
22099636 | Outcomes for depression and anxiety in primary care and details of treatment: a naturalistic longitudinal study. | There is little evidence as to whether or not guideline concordant care in general practice results in better clinical es for people with anxiety and depression. This study aims to determine possible associations between guideline concordant care and clinical es in general practice patients with depression and anxiety,... |
22099638 | Prevalence of neuroleptic-induced restless legs syndrome in patients taking neuroleptic drugs. | Dopamine deficiency or dopamine dysfunction has been implicated as one of the factors involved in the pathophysiology of restless legs syndrome (RLS). Our objective is to determine the prevalence of primary RLS in patients taking neuroleptic drugs. One hundred patients taking neuroleptic drugs and 100 healthy age- and ... |
22099639 | Influence of visual cues on gait in Parkinson's disease during treadmill walking at multiple velocities. | To evaluate the interaction of different treadmill-induced gait velocities and visual cues on the gait performance in Parkinson's disease (PD). |
22099640 | Polyethylene glycol-coated solid-phase microextraction fibres for the extraction of polar analytes--a review. | The article discusses the merits and limitations mercially available solid-phase microextraction (SPME) fibres pares them with the new type of extraction coatings, in particular those containing polyethylene glycol as sorbent, as well as the methods of the preparation of the latter. It also analyses their possible appl... |
22099641 | Neptunium(III) application in extraction chromatography. | This paper describes a novel strategy for actinide separation by extraction chromatography with Np(III) valence adjustment. Neptunium(IV) was reduced to Np(III) using Cr(II) and then selectively separated from uranium (IV) on a TEVA resin. After elution, Np(III) was retained on a DGA resin in order to remove any detrim... |
22099642 | Preparation and characterization of bismuth oxide nanoparticles-multiwalled carbon nanotube composite for the development of horseradish peroxidase based H₂O₂ biosensor. | In this work, preparation and characterization of a novel posite containing bismuth oxide (Bi(2)O(3)) nanoparticles and multiwalled carbon nanotubes (MWCNTs) was presented. Powder X-ray diffraction (XRD) studies revealed that as-synthesized Bi(2)O(3) nanoparticles are crystalline and belong to α-phase with monoclinic s... |
22099643 | Multielement analysis of micro-volume biological samples by ICP-MS with highly efficient sample introduction system. | A method for multielement analysis of micro-volume biological sample by inductively coupled plasma mass spectrometry (ICP-MS) with a highly efficient sample introduction system was presented. The sample introduction system was bination of (1) an inert loop injection unit and (2) a high performance concentric nebulizer ... |
22099645 | Determination of fullerenes (C60) in artificial sediments by liquid chromatography. | In this new century, nanotechnology has evolved from a novel concept to an integral aspect of product advancement. With an increasing presence of nanomaterials mercial products, more concern about the impact of nanomaterials on human health and also the environment has been considered and evaluated. Fullerenes (C60), h... |
22099644 | Determination of biodiesel content in biodiesel/diesel blends using NIR and visible spectroscopy with variable selection. | This work is concerned of evaluate the use of visible and near-infrared (NIR) range, separately bined, to determine the biodiesel content in biodiesel/diesel blends using Multiple Linear Regression (MLR) and variable selection by Successive Projections Algorithm (SPA). Full spectrum models employing Partial Least Squar... |
22099646 | Novel PVC-membrane electrode for flow injection potentiometric determination of Biperiden in pharmaceutical preparations. | The construction and performance characteristics of Biperiden (BP) polyvinyl chloride (PVC) electrodes are described. Different methods for electrode fabrication are tested including; incorporation of BP-ion pairs (BP-IPs), incorporation of ion pairing agents, or soaking the plain electrode in BP-ion pairs suspension s... |
22099647 | Wavelets and genetic algorithms applied to search prefilters for spectral library matching in forensics. | Currently, the identification of the make, model and year of a motor vehicle involved in a hit and run collision from only a clear coat paint smear left at a crime scene is not possible. Search prefilters for searching infrared (IR) spectral libraries of the paint data query (PDQ) automotive database to differentiate b... |
22099648 | Laser-induced breakdown spectroscopy-based investigation and classification of pharmaceutical tablets using multivariate chemometric analysis. | We report the effectiveness of laser-induced breakdown spectroscopy (LIBS) in probing the content of pharmaceutical tablets and also investigate its feasibility for routine classification. This method is particularly beneficial in applications where its exquisite chemical specificity and suitability for remote and on s... |
22099649 | Assessment uncertainty associated to the analysis of tar from gasification of sewage sludge. | The uncertainty evaluation associated with the quantification of tar from gasification of sewage sludge is present. Each of the sources of uncertainty associated with the wet type sampling method and GC-MS analysis was identified to determine the critical stages of the analytical methodology in order to reduce them. Th... |
22099650 | Modified gold surfaces by poly(amidoamine) dendrimers and fructose dehydrogenase for mediated fructose sensing. | An electrochemical biosensor for detection of fructose in food samples was developed by immobilization of fructose dehydrogenase (FDH) on cysteamine and poly(amidoamine) dendrimers (PAMAM)-modified gold electrode surface. Electrochemical analysis was carried out by using hexacyanoferrate (HCF) as a mediator and the res... |
22099651 | Molecularly imprinted polymers for separation of various sugars from human urine. | Molecularly imprinted polymers were the new, simple and unexpensive materials that can be used in several clinical applications. Phenylboronic acid has been frequently used as functional monomer for the covalent imprinting of diols. In this study, the phenylboronic acid esters of fructose, galactose, glucose and raffin... |
22099652 | In vitro monitoring of natural thorium in urine using fluorimeter. | A relatively less expensive and less time consuming radio analytical technique for quantitative determination of Th(nat) in urine at mBq level is developed and reported in this paper. Th in urine is co-precipitated with Ca(3)(PO(4))(2) from wet oxidized urine matrix and the precipitate is dissolved in HNO(3) and evapor... |
22099653 | An adaptable automatic trace metal monitoring system for on line measuring in natural waters. | An adaptable automatic trace metal monitoring system (ATMS) was assembled and embedded in a mobile monitoring station belonging to the French Water Agency Artois-Picardie (AEAP) and deployed in the field to measure the concentration of trace metals (electroactive and acid leachable fractions) in natural waters by anodi... |
22099654 | Visual detection of organophosphorus pesticides represented by mathamidophos using Au nanoparticles as colorimetric probe. | With citrate-coated Au nanoparticles as colorimetric probe, a novel visual method for rapid assay of organophosphorus pesticides has been developed. The assay principle is based on catalytic hydrolysis of acetylthiocholine into thiocholine by acetylcholinesterase, which induces the aggregation of Au nanoparticles and t... |
22099655 | Label-free immunoassay for chloramphenicol based on hollow gold nanospheres/chitosan composite. | A novel label-free electrochemical immunosensor for rapid determination of chloramphenicol (CAP) was fabricated by entrapping monoclonal antibody to chloramphenicol (anti-CAP) in hollow gold nanospheres posite modified on a glassy carbon electrode. The hollow gold nanospheres (HGNs) were prepared by using Co nanopartic... |
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