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24210892 | Monolithic graphene fibers for solid-phase microextraction. | Monolithic graphene fibers for solid-phase microextraction (SPME) were fabricated through a dimensionally confined hydrothermal strategy and their extraction performance was evaluated. For the fiber fabrication, a glass pipeline was innovatively used as a hydrothermal reactor instead of a Teflon-lined autoclave. Compar... |
24210893 | Telepulmonology: effect on quality and efficiency of care. | Interpreting spirometry results has proven challenging in primary care practice, among others potentially leading to under- and misdiagnosis of COPD. In telepulmonology a general practitioner (GP) digitally consults a pulmonologist to support the interpretation of spirometry results. This study assessed the effect of t... |
24210895 | Mass spectrometric quantification of L-arginine and its pathway related substances in biofluids: the road to maturity. | The amino acid L-arginine together with its metabolites and related substances is in the center of many biologically important pathways, especially the urea cycle and the nitric oxide (NO) synthesis. Therefore, the concentrations of these substances in various biological fluids are of great interest as predictive marke... |
24210894 | Targeting and mimicking collagens via triple helical peptide assembly. | As the major ponent of the extracellular matrix, collagen plays a crucial role in tissue development and regeneration. Since structural and metabolic abnormalities of collagen are associated with numerous debilitating diseases and pathologic conditions, the ability to target collagens of diseased tissues could lead to ... |
24210896 | Skeletal stability of bioresorbable fixation in orthognathic surgery: a systemic review. | Over the past 20 years, there has been an increase in the use of bioresorbable fixation system in orthognathic surgery, but concerns remain about the stability of fixation. This review is to seek evidence for the effectiveness of bioresorbable fixation pared to titanium systems used for orthognathic surgery. |
24210897 | The prevalence of chronic health conditions impacting on daily functioning and the association with emotional well-being among a national sample of high school students. | This study aims to describe the prevalence of self-reported chronic health conditions among high school students in New Zealand, the extent to which the condition impacts on their activities and socialization, and to explore the association between the level of impact of the illness or disability and the emotional well... |
24210898 | Preventing adolescent alcohol use: effects of a two-year quasi-experimental community intervention intensifying formal and informal control. | To determine the effect on adolescent alcohol use of munity bining intensified formal control (restricting retail supply) and informal control (restricting social supply). Intervention effects on intermediate intervention goals were investigated. Analyses for different age groups were performed. |
24210899 | Adolescent use of the emergency department instead of the primary care provider: who, why, and how urgent? | Adolescents frequently rely on emergency medical care, rather than using primary care providers (PCPs). Our objectives were to characterize a population of adolescents presenting to a large, urban emergency department (ED) and to examine the reasons why they present to the ED, rather than to their PCP's office. |
24210900 | Sinonasal manifestations of cystic fibrosis: a correlation between genotype and phenotype? | Patients with Cystic Fibrosis are prone to develop sinonasal disease. Studies in genotype-phenotype correlations for sinonasal disease are scarce and inconclusive. |
24210901 | Manipulating sleep spindles--expanding views on sleep, memory, and disease. | Sleep spindles are distinctive electroencephalographic (EEG) oscillations emerging during non-rapid-eye-movement sleep (NREMS) that have been implicated in multiple brain functions, including sleep quality, sensory gating, learning, and memory. Despite considerable knowledge about the mechanisms underlying these neuron... |
24210902 | Role of adipokines and cytokines in obesity-associated breast cancer: therapeutic targets. | Obesity is the cause of a large proportion of breast cancer incidences and mortality in post-menopausal women. In obese people, elevated levels of various growth factors such as insulin and insulin-like growth factors (IGFs) are found. Elevated insulin level leads to increased secretion of estrogen by binding to the ci... |
24210903 | Non-invasive prenatal testing for Down syndrome. | Prenatal screening and diagnosis of Down syndrome and other major aneuploidies may be transformed following the identification of cell-free fetal DNA in maternal plasma at the end of the last millennium. Next generation sequencing has enabled the development of tests that accurately predict the presence of fetal trisom... |
24210904 | Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. | Reelin is a glycoprotein that is critical for proper layering of neocortex during development as well as dynamic regulation of glutamatergic postsynaptic signaling in mature synapses. Here, we show that Reelin also acts presynaptically, resulting in robust rapid enhancement of spontaneous neurotransmitter release witho... |
24210905 | Encoding of mixtures in a simple olfactory system. | Natural odors are usually mixtures; yet, humans and animals can experience them as unitary percepts. Olfaction also enables stimulus categorization and generalization. We studied how putations are performed with the responses of 168 locust antennal lobe projection neurons (PNs) to varying mixtures of two monomolecular ... |
24210906 | Regulation of axon degeneration after injury and in development by the endogenous calpain inhibitor calpastatin. | Axon degeneration is widespread both in neurodegenerative disease and in normal neural development, but the molecular pathways regulating these degenerative processes and the extent to which they are distinct or overlapping remain pletely understood. We report that calpastatin, an inhibitor of calcium-activated proteas... |
24210907 | Spike-timing-dependent plasticity in primate corticospinal connections induced during free behavior. | Motor learning and functional recovery from brain damage involve changes in the strength of synaptic connections between neurons. Relevant in vivo evidence on the underlying cellular mechanisms remains limited and indirect. We found that the strength of neural connections between motor cortex and spinal cord in monkeys... |
24210909 | Effects in cattle of genetic variation within the IGF1R gene on the superovulation performance and pregnancy rates after embryo transfer. | The insulin-like growth factor 1 receptor (IGF1R) is a membrane glycoprotein mediating most biological actions of IGF1 and IGF2, and has an important effect on ovulation, pre-implantation embryo development and pregnancy rate. The objectives of this study were to detect IGF1R gene polymorphisms of cattle and analyze th... |
24210908 | Noncanonical FK506-binding protein BDBT binds DBT to enhance its circadian function and forms foci at night. | The kinase DOUBLETIME is a master regulator of the Drosophila circadian clock, yet the mechanisms regulating its activity remain unclear. A proteomic analysis of DOUBLETIME interactors led to the identification of an unstudied protein designated CG17282. RNAi-mediated knockdown of CG17282 produced behavioral arrhythmic... |
24210910 | Effect of cryopreservation and single layer centrifugation on canine sperm DNA fragmentation assessed by the sperm chromatin dispersion test. | The aims of this study were: 1) to assess the effect of freezing and thawing on dog sperm DNA fragmentation index (sDFI) using the sperm chromatin dispersion test (SCDt); and 2) to determine whether or not the sperm selection by single layer centrifugation (SLC) using Androcoll-C improves sperm DNA longevity in SLC-sel... |
24210914 | Rapid construction of sigmoid bladder augmentation using absorbable staples: long-term results and comparison to standard colocystoplasty in children with neurogenic bladder. | Absorbable staples facilitate detubularization and reconfiguration of the bowel when performing augmentation colocystoplasty. pared the es of stapled sigmoid augmentation with standard sutured colocystoplasty. |
24210915 | Protective effect of esterified glucomannan on aflatoxin-induced changes in testicular function, sperm quality, and seminal plasma biochemistry in rams. | The aim of this study was to determine the effect of aflatoxin (AF) on spermatologic, biochemical, and testis parameters in rams, and the protective efficiency of esterified annan (EG) co-administered with AF. Thirty-two Merino rams (12-14 months old) were used. The experimental design consisted of four dietary treatme... |
24210916 | Cryogenic changes in proteases and antiprotease activities of buffalo (Bubalus bubalis) and cattle (Bos taurus) semen. | The postthaw motility and fertility of buffalo and cattle semen is reduced when they are cryopreserved for artificial insemination. In the present study, an attempt was made to characterize the cryogenic changes in proteases and antiprotease activities (APA) of buffalo and cattle semen because these proteolysis regulat... |
24210918 | Transcriptome surveillance by selective termination of noncoding RNA synthesis. | Pervasive transcription of eukaryotic genomes stems to a large extent from bidirectional promoters that synthesize mRNA and divergent noncoding RNA (ncRNA). Here, we show that ncRNA transcription in the yeast S. cerevisiae is globally restricted by early termination that relies on the essential RNA-binding factor Nrd1.... |
24210919 | Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance. | The regulation of protein-coding and noncoding RNAs is linked to nuclear processes, including chromatin modifications and gene silencing. However, the mechanisms that distinguish RNAs and mediate their functions are poorly understood. We describe a nuclear RNA-processing network in fission yeast with a core prising the... |
24210920 | Merits of usability testing for PACS selection. | pare the usability of different Picture Archiving and Communication System (PACS) workstations, determine whether a usability test has added value with respect to the traditional way paring PACSs based on functional requirements, and to evaluate the appropriateness of a task-based methodology for a PACS usability test. |
24210921 | Thermal and electron stimulated luminescence of natural bones, commercial hydroxyapatite and collagen. | The luminescence (cathodoluminescence and thermoluminescence) properties of natural bones (Siberian mammoth and adult mercial hydroxyapatite and collagen were analyzed. Chemical analyses of the natural bones were determined using by Electron Probe Micro-Analysis (EMPA). Structural, molecular and thermal characteristics... |
24210922 | The burden of childhood asthma and late preterm and early term births. | To evaluate the association between gestational age at birth and the risk of subsequent development of asthma. |
24210917 | Risky sexual behaviors: The role of ethnic identity in HIV risk in migrant workers. | Migrant workers have been shown to be at a heightened level of risk for HIV, and ethnic identity has been posited to have an impact on engagement in risky sexual behaviors. Our longitudinal study examined associations between baseline and short-term changes in ethnic identity and high-risk sexual behaviors. Baseline (n... |
24210925 | Hypothermia and early neonatal mortality in preterm infants. | To evaluate intervention practices associated with hypothermia at both 5 minutes after birth and at neonatal intensive care unit (NICU) admission and to determine whether hypothermia at NICU admission is associated with early neonatal death in preterm infants. |
24210927 | Brain magnetic resonance imaging in infants with surgical necrotizing enterocolitis or spontaneous intestinal perforation versus medical necrotizing enterocolitis. | Magnetic resonance imaging of the brain was performed in 26 preterm infants with necrotizing enterocolitis (NEC) or spontaneous intestinal perforation at term equivalent age. Infants with surgical NEC or spontaneous intestinal perforation had significantly more brain injury on magnetic resonance pared with infants with... |
24210928 | Light sleep versus slow wave sleep in memory consolidation: a question of global versus local processes? | Sleep is strongly involved in memory consolidation, but its role remains unclear. 'Sleep replay', the active potentiation of relevant synaptic connections via reactivation of patterns of network activity that occurred during previous experience, has received considerable attention. Alternatively, sleep has been suggest... |
24210929 | Office-based endovascular suite is safe for most procedures. | This study was conducted to identify the safety of endovascular procedures in the office endovascular suite and to assess patient satisfaction in this setting. |
24210930 | Inflammation is more distinct in temporomandibular joint osteoarthritis compared to the knee joint. | Most of the current understanding of articular cartilage maintenance and degradation is derived from large load-bearing synovial joints, in particular the knee joint. The aim of this study was to identify valuable degradation markers for cartilage degradation in the temporomandibular joint (TMJ) paring the relative con... |
24210923 | Variation in feeding practices following the Norwood procedure. | To assess variation in feeding practice at hospital discharge after the Norwood procedure, factors associated with tube feeding, and associations among site, feeding mode, and growth before stage II. |
24210931 | [Treatment of high myopic choroidal neovascularisation with intravitreal bevacizumab]. | To evaluate the safety and efficacy of intravitreal bevacizumab (IVB) in the treatment of high myopic choroidal neovascularization (CNV). |
24210934 | [Anatomical and functional prognosis of secondary retinal detachments after sutureless macular surgery]. | To evaluate the incidence, characteristics and risk factors for plications of transconjunctival sutureless 23-gauge vitrectomy (TSV) in macular surgery. The results were correlated with those reported in the literature. |
24210935 | [Optical quality after 2.2mm microincisional cataract surgery with bimanual I/A in 154 eyes]. | A prospective study to analyze the effects of 2.2mm microincisional coaxial phacoemulsification with bimanual irrigation/aspiration on the optical quality of the cornea and whole eye. |
24210936 | [Results of natural hydroxyapatite implants covered with Vicryl® mesh in a series of 704 enucleations]. | Retrospective study of local tolerability of a natural hydroxyapatite orbital implant wrapped with Vicryl(®) (polyglactin) mesh in patients undergoing enucleation. |
24210941 | Chromatographic techniques coupled with mass spectrometry for the determination of organic acids in the study of autism. | Chromatographic methods find application in the diagnostics and prognosis of diseases. They are used in finding new biomarkers, which may result in early medical intervention. Early diagnosis and intervention are especially important in the case of diseases of unknown etiology. One of these is autism. Autism is a neuro... |
24210942 | The social brain: neurobiological basis of affiliative behaviours and psychological well-being. | The social brain hypothesis proposes that the demands of the social environment provided the evolutionary pressure that led to the expansion of the primate brain. Consistent with this notion, that functioning in the social world is crucial to our survival, while close supportive relationships are known to enhance well-... |
24210944 | Ecology of the ciguatera causing dinoflagellates from the Northern Great Barrier Reef: changes in community distribution and coastal eutrophication. | Ciguatera fish poisoning (CFP) is known to be caused by the ciguatoxins from the dinoflagellate genus Gambierdiscus, however, there is the potential for other toxins such as okadaic acid and dinophysistoxins from the genus Prorocentrum, and palytoxin from the genus Ostreopsis, to contaminate seafood. These genera may a... |
24210945 | Sublethal effects of a chlorinated and heated effluent on the physiology of the mussel, Mytilus edulis L.: a reduction in fitness for survival? | Coastal power stations entrain large volumes of cooling water, requiring biocidal treatment to prevent biological fouling. Discharged effluent is both heated and contaminated with residual traces of biocide and so it is necessary to quantify the impacts of this discharge. Cooling water from Heysham 2 nuclear power stat... |
24210943 | The role of maternal care in shaping CNS function. | Maternal care involves the consistent and coordinated expression of a variety of behaviours over an extended period of time, and adverse changes in maternal care can have profound impacts on the CNS and behaviour of offspring. plex behavioural pattern depends on a number of integrated neuroendocrine mechanisms. This re... |
24210946 | Biodegradation of low-density polyethylene by marine bacteria from pelagic waters, Arabian Sea, India. | Sixty marine bacteria isolated from pelagic waters were screened for their ability to degrade low-density polyethylene; among them, three were positive and able to grow in a medium containing polythene as the sole carbon source. The positive isolates were identified as Kocuria palustris M16, Bacillus pumilus M27 and Ba... |
24210947 | Quantitative analysis of plastic debris on recreational beaches in Mumbai, India. | Plastic litter was quantified on four sandy beaches in Mumbai. The mean abundance of 7.49 g and 68.83 items per square metre was recorded. The abundance of plastics significantly varied among the beaches showing an increasing trend in the southern part. The abundance of plastics by weight in Dadar was significantly hig... |
24210948 | Basal ganglia volume in unmedicated patients with schizophrenia is associated with treatment response to antipsychotic medication. | We investigated the relationship between basal ganglia volume and treatment response to the atypical antipsychotic medication risperidone in unmedicated patients with schizophrenia. Basal ganglia volumes included the bilateral caudate, putamen, and pallidum and were measured using the Freesurfer automated segmentation ... |
24210949 | The impact of timing of cholecystectomy following gallstone pancreatitis. | Current guidelines for the management of acute gallstone pancreatitis mend cholecystectomy as definitive treatment during primary admission or within 2 weeks of discharge, with the aim of preventing recurrent pancreatitis. However, cholecystectomy during the inflammatory phase may increase plication rates. This study a... |
24210950 | Environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish Pimephales promelas (fathead minnow). | Pharmaceuticals and personal care products (PPCPs) have been found in surface waters worldwide, but little is understood of their effects on the wildlife that inhabit these waters. Fluoxetine (Prozac; Eli Lilly), a highly prescribed selective serotonin reuptake inhibitor (SSRI), is monly found PPCP in surface water. Th... |
24210952 | A closer look at the relationship between the subdomains of social functioning, social cognition and symptomatology in clinically stable patients with schizophrenia. | Impairments in social monly seen in schizophrenia are thought to be mediated by deficits in the domains of social cognition. Some previous research has explored how social cognitive skills and psychotic symptoms are associated with social functioning, however these associations are still under debate. The main aim of t... |
24210953 | The effect of a rapid rehydration guideline on Emergency Department management of gastroenteritis in children. | This study evaluated the use and effect of a rapid rehydration guideline for the management of gastroenteritis in children 6months to 4years of age in an Emergency Department (ED). The guideline aims to facilitate rehydration within 4h of arrival to the ED, using oral or nasogastric fluids. Primary e measures were ED L... |
24210954 | The desired competence of the Swedish ambulance nurse according to the professionals - a Delphi study. | Nursing is evolving into new fields of health care including ambulance care, where a branch of specialist nursing is growing. Various views exist on the petence for the ambulance nurse and valid guidelines are lacking in Sweden. To increase knowledge of the field, professionals were asked to describe petences an ambula... |
24210955 | Impacts of the introduction of a triage system in Japan: a time series study. | The aim of the present study was to measure pare the effectiveness of nursing triage before and after introduction of the Japanese Triage and Acuity Scale (JTAS), the Japanese version of the Canadian Triage and Acuity Scale (CTAS), during emergency treatment. Surveys of triage nurses and emergency physicians were condu... |
24210956 | Perpetuating proficiency in donor right hepatectomy for living donor liver transplantation. | Donor right hepatectomy (DRH) was developed by master liver surgeons and has been applied in many liver transplant centers as the mainstay for adult living donor liver transplantation. It is a major plex surgical operation performed on living liver donors for the benefit of liver recipients. The donors deserve the lowe... |
24210957 | CD8 TCR β chain repertoire expansions and deletions are related with immunologic markers in HIV-1-infected patients during treatment interruption. | HIV-1-infected individuals progressively loss CD4(+) T cells leading to immunosuppression and raising the risk of opportunistic infections. CD8(+) T-cells play an important role in the immune response against virus infections through their TCR. |
24210958 | Diagnostic performance of selected commercial HEV IgM and IgG ELISAs for immunocompromised and immunocompetent patients. | Hepatitis E virus (HEV) genotype 3 is recognised as an emerging pathogen in industrialised countries. The mercially available HEV-specific enzyme linked immunosorbent assays (ELISAs) are primarily designed for the detection of antibodies against genotypes 1 (Burma) and 2 (Mexico) and may not sensitively detect HEV geno... |
24210960 | Aberrant functional connectivity between motor and language networks in rolandic epilepsy. | Rolandic epilepsy (RE) is an idiopathic focal childhood epilepsy with a well-established neuropsychological profile of language impairment. The aim of this study is to provide a functional correlate that links rolandic (sensorimotor) pathology to language problems using functional MRI. |
24210961 | Regional brain activity change predicts responsiveness to treatment for stuttering in adults. | Developmental stuttering is known to be associated with aberrant brain activity, but there is no evidence that this knowledge has benefited stuttering treatment. This study investigated whether brain activity could predict progress during stuttering treatment for 21 dextral adults who stutter (AWS). They received one o... |
24210963 | The evolution of distributed association networks in the human brain. | The human cerebral cortex is vastly expanded relative to other primates and disproportionately occupied by distributed association regions. Here we offer a hypothesis about how association networks evolved their prominence and came to possess circuit properties vital to human cognition. The rapid expansion of the corti... |
24210962 | Cognitive aging: is there a dark side to environmental support? | It has been known for some time that memory deficits among older adults increase when self-initiated processing is required and decrease when the environment provides task-appropriate cues. We propose that this observation is not confined to memory but can be subsumed under a more general developmental trend. In percep... |
24210964 | Light microscopy mapping of connections in the intact brain. | Mapping of neural connectivity across the mammalian brain is a daunting and exciting prospect. Current approaches can be divided into three classes: macroscale, focusing on coarse inter-regional connectivity; mesoscale, involving a finer focus on neurons and projections; and microscale, reconstructing full details of a... |
24210965 | Mediastinal abscess and esophageal stricture following voice prosthesis insertion. | The use of a tracheo-esophageal voice prosthesis is a well-established procedure to restore the voice in total laryngectomees. The insertion of the prosthesis is not a risk-free procedure, plications having been reported especially in irradiated patients. Here described is a case of an esophageal rupture after secondar... |
24210966 | In vitro development of goat-sheep and goat-goat zona-free cloned embryos in different culture media. | The gradual decline in the genetic diversity of farm animals has threatened their survival and risk of their extinction has increased many fold in the recent past. Endangered species could be rescued using interspecies embryo production. The objective of this study was to investigate the effect of three different cultu... |
24210968 | [A surgical follow-up platform to reduce complications in free flap surgery]. | In 2007, the WHO adopted surgical safety as the theme for the 2nd global patient safety challenge. Measurement of surgical services was identified as a surgical care area in need of major improvements. Aware of this mendation, a preliminary study was conducted in our hospital and showed that the incidence plete necrosi... |
24210970 | Cutaneous human papillomavirus types detected on the surface of male external genital lesions: a case series within the HPV Infection in Men Study. | Cutaneous human papillomaviruses (HPVs) may be associated with cutaneous epithelial lesions and non-melanoma skin cancers. No study has systematically evaluated the presence of genus beta [β]-HPV in male genital skin or external genital lesions (EGLs) |
24210971 | A novel core biopsy technique for anterior cruciate ligament preserves ligament structural integrity: a porcine study. | The objective of this study was to validate a new technique to safely obtain core biopsy specimens of the anterior cruciate ligament (ACL) without jeopardizing the ACL's biomechanical properties. |
24210973 | A content analysis of food references in television programming specifically targeting viewing audiences aged 11 to 14 years. | Examine food in cable television programming specifically targeting 11- to 14-year-olds ("tweens"). |
24210974 | Assessment of cytotoxic and immunomodulatory properties of four antidepressants on primary cultures of abalone hemocytes (Haliotis tuberculata). | pounds like antidepressants found in surface waters raise concerns due to their potential toxicity on non-target aquatic organisms. This study aimed at investigating the in vitro cytotoxicity and immunomodulatory properties of mon antidepressants, namely Amitriptyline, Clomipramine, Citalopram and Paroxetine, on primar... |
24210978 | [Diagnostic ability of Chronic Kidney Disease Epidemiology Collaboration and Modification of Diet in Renal Disease-4 equations to estimate glomerular filtration rate in with multimorbidity patients]. | The Modification of Diet in Renal Disease (MDRD) equation is mended by most scientific societies to calculate the estimated glomerular filtration rate (GFR). Recently the group Chronic Kidney Disease Epidemiology Collaboration (CKP-EPI) has published a new, more precise and accurate equation. We have analyzed its behav... |
24210982 | [Usefulness of the Chronic Obstructive Pulmonary Disease Assessment Test in chronic obstructive pulmonary disease with severe airflow limitation]. | To evaluate the relationship between Chronic Obstructive Pulmonary Disease Assessment Test (CAT questionnaire) and chronic obstructive pulmonary disease (COPD) severity assessed by the multidimensional BODE index in patients with severe airflow obstruction (forced expiratory volume in one second [FEV1] post-bronchodila... |
24210983 | [Results of an early intervention program for patients with bacteremia discharged from the Emergency Department]. | Occult bacteremia represents 3% of blood cultures drawn in the Emergency Department. In most cases, the evolution is unknown. The aim of the study is to analyze the results obtained after implementation of an intervention program for these patients. |
24210985 | [Aquagenic palmoplantar keratoderma in children with cystic fibrosis]. | Aquagenic palmoplantar keratoderma (APK) is a cutaneous phenomenon marked by the formation of edematous, translucent papules and plaques on the palms after water immersion. It can be observed in healthy subjects, but while this dermatosis is little known by practitioners treating these patients, most cases of APK have ... |
24210986 | [Trisomy 21 in visual art]. | In 1866, J. Langdon Down published a paper on "an ethnic classification of idiots" and noted their facial resemblance with individuals of the Mongolian people. In 1959, J. Lejeune, M. Gautier, and R. Turpin demonstrated that the children with Down syndrome had an extra copy of chromosome 21. There is now a debate withi... |
24210991 | Endoscopic treatment of iatrogenic gastrointestinal perforations: an overview. | In the past, the treatment of iatrogenic gastrointestinal perforations was limited to surgical management or to medical observation. Natural Orifice Transluminal Endoscopic Surgery (NOTES) has paved the way towards the development of reliable endoscopic closure techniques, which can be applicable in accidental perforat... |
24210987 | Prevalence, predictors and evolution of echocardiographically defined cardiac abnormalities in adults with type 1 diabetes: an observational cohort study. | The aims of this observational study were to determine the prevalence and predictors of an abnormal echocardiogram in adults with type 1 diabetes, and to assess the evolution of changes in a subset of subjects. |
24210992 | Analysis of interobserver variability for endomicroscopy of the gastrointestinal tract. | Endomicroscopy allows in vivo microscopic investigation of enteral mucosa during endoscopic examinations. The aim of this study was to determine interobserver variability in the evaluation of endomicroscopic pictures of several organs by groups of posed of confocal experts, pathologists and students. |
24210993 | Phosphorylated Crkl reduction levels are associated with the lowest P-glycoprotein activity levels in cells from chronic myeloid leukemia patients. | ABCB1/P-glycoprotein (Pgp) and ABCG2/BCRP overexpression have been described as related to imatinib resistance in chronic myeloid leukemia (CML). We showed in CML cells from 55 patients that Pgp activity was more frequently detected than BCRP activity (p=0.0074). Imatinib-induced Crkl phosphorylated protein (pCrkl) red... |
24210996 | Psychophysiological correlates of coping and quality of life in patients with ALS. | Self-regulation models of coping suggest that patients with chronic diseases reporting low quality of life (QoL), an indicator of failed coping efforts, should show facilitated access to disease related words. Here we investigated whether a reduced N400 amplitude within an incongruent, i.e. unpredictable disease-relate... |
24210999 | New SSU-rDNA sequences for eleven colpodeans (Ciliophora, Colpodea) and description of Apocyrtolophosis nov. gen. | Using 11 new SSU-rDNA sequences, we analyze relationships within the class Colpodea, especially of some mon taxa, such as Kalometopia duplicata, Cyrtolophosis minor, and Jaroschia sumptuosa. The sequences do not change the basic structure of the molecular Colpodea tree, i.e., all belong to one of the four molecular cla... |
24210997 | Brain activity during complex imagined gait tasks in Parkinson disease. | Motor imagery during functional magnetic resonance imaging (fMRI) allows assessment of brain activity during tasks, like walking, that cannot pleted in an MRI scanner. We used gait imagery to assess the neural pathophysiology of otion in Parkinson disease (PD). |
24211000 | Effect of patient-controlled sedation with propofol on patient satisfaction: a randomized study. | In this trial we sought to determine whether propofol-based patient-controlled sedation (PCS) during diagnostic cerebral angiography would result in improved patient pared to placebo-based PCS. |
24211002 | [History of pediatric anesthesia: from the beginnings to the end of the 19th century]. | The first intuitions and descriptions of anesthesia can be found in the antique civilizations. In the 19th century, the invention of anesthesia took place in Boston, and quickly spread to Europe. In France, regulations and structures were created before the beginning of the 20th century to organize this new profession,... |
24211006 | Anti-NMDAR autoimmune encephalitis. | The N-methyl-D-aspartate receptor (NMDAR) is involved in normal physiological and pathological states in the brain. Anti-NMDAR encephalitis is characterized by memory deficits, seizures, confusion, and psychological disturbances in males and females of all ages. This type of encephalitis is often associated with ovaria... |
24211003 | Dissociation of preparatory attention and response monitoring maturation during adolescence. | Substantial brain development occurs during adolescence providing the foundation for functional advancement from stimulus-bound "bottom-up" to more mature executive-driven "top-down" processing strategies. The objective was to assess development of EEG markers of these strategies and their role in both preparatory atte... |
24211007 | Resting state functional connectivity alterations in primary lateral sclerosis. | Resting state functional connectivity of the sensorimotor and extramotor brain networks was studied in 24 patients with primary lateral sclerosis (PLS) relative to 26 healthy controls. The relationships of RS functional connectivity with patient clinical and cognitive status and white matter tract damage (i.e., cortico... |
24211009 | Role for the neurexin-neuroligin complex in Alzheimer's disease. | Synaptic damage is a critical hallmark of Alzheimer's disease, and the best correlate with cognitive impairment ante mortem. Synapses, the loci munication between neurons, are characterized by signature binations arrayed at tightly apposed pre- and post-synaptic sites. The most widely studied trans-synaptic plexes, whi... |
24211008 | Operationalizing hippocampal volume as an enrichment biomarker for amnestic mild cognitive impairment trials: effect of algorithm, test-retest variability, and cut point on trial cost, duration, and sample size. | The objective of this study was to evaluate the effect putational algorithm, measurement variability, and cut point on hippocampal volume (HCV)-based patient selection for clinical trials in mild cognitive impairment (MCI). We used normal control and amnestic MCI subjects from the Alzheimer's Disease Neuroimaging Initi... |
24211010 | Aging is associated with changes in the neural circuits underlying empathy. | Although the neurodevelopment of empathy from childhood to adolescence has been documented, no study has yet examined it across a life span aging perspective. Sixty-five healthy participants from 3 age groups (young, middle-aged, old) underwent functional magnetic resonance imaging while presented with visual stimuli d... |
24211011 | Prevalence, use and sale of contact lenses in Saudi Arabia: survey on university women and non-ophthalmic stores. | To assess the prevalence and general knowledge of contact lens (CL) wear among women users and to examine the practice of CL dispensation by non-ophthalmic stores. |
24211012 | References from Brazilian medical journals in national publications. | To assess whether there is a preference for international journal citation to the detriment of national ones in ten Brazilian medical journals, in two different periods. |
24211016 | Defining the anti-inflammatory activity of a potent myxomaviral chemokine modulating protein, M-T7, through site directed mutagenesis. | Viral chemokine modulating proteins provide new and extensive sources for therapeutics. Purified M-T7, a poxvirus-derived secreted immunomodulatory protein, reduces mononuclear cell invasion and atheroma in rodent models of angioplasty injury as well as aortic and renal transplant, improving renal allograft survival. M... |
24211018 | Suggestions for a Web based universal exchange and inference language for medicine. | Mining biomedical and pharmaceutical data generates huge numbers of interacting probabilistic statements for inference, which can be supported by mining Web text sources. This latter can also be probabilistic, in a sense described in this report. However, the diversity of tools for probabilistic inference is troublesom... |
24211015 | Arteriographic findings in diabetic and non-diabetic with critical limb ischemia. | pare angiographic findings of diabetic and non-diabetic patients with critical limb ischemia. |
24211019 | Truncated and constrained helical analogs of antimicrobial esculentin-2EM. | Esculentin-2EM is a 37-residue, cationic, amphipathic, α-helical antimicrobial peptide isolated from a Korean frog, Glandirama emeljanovi. Many studies revealed that truncation of this peptide results in substantial decreases in its antimicrobial activity. Lee and his colleagues have recently reported that a 23-residue... |
24211017 | Detailed assessments of childhood adversity enhance prediction of central obesity independent of gender, race, adult psychosocial risk and health behaviors. | This study examined whether a novel indicator of overall childhood adversity, incorporating number of adversities, severity, and chronicity, predicted central obesity beyond contributions of "modifiable" risk factors including psychosocial characteristics and health behaviors in a diverse sample of midlife adults. The ... |
24211013 | Rebound effect of modern drugs: serious adverse event unknown by health professionals. | Supported in the Hippocratic aphorism primum non nocere, the bioethical principle of non-maleficence pray that the medical act cause the least damage or injury to the health of the patient, leaving it to the doctor to assess the risks of a particular therapy through knowledge of possible adverse events of drugs. Among ... |
24211014 | Chronic obstructive pulmonary disease in women exposed to wood stove smoke. | To identify respiratory symptoms and COPD (forced vital capacity and forced expiratory volume in one second ratio < 0.70 and below the lower limit of normal) in non-smoking women with history of exposure to wood smoke of at least 80 hours-years. |
24211020 | Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands. | Selective σ2 ligands continue to be an active target for medications to attenuate the effects of psychostimulants. In the course of our studies to determine the optimal substituents in the σ2-selective phenyl piperazines analogues with reduced activity at other neurotransmitter systems, we discovered that 1-(3-chloroph... |
24211021 | Synthesis and antitumor activity evaluation of maleopimaric acid N-aryl imide atropisomers. | Maleopimaric acid N-aryl imides (2) and methyl maleopimaric acid N-aryl imides (3) were designed and synthesized. Their atropisomers (A and B) were separated into their enantiomeric pure forms and the anti-proliferative activity was tested against NCI, A549, Hep G-2, MGC-803 and Hct-116 cell lines, respectively. A sign... |
24211022 | Discovery of a potent respiratory syncytial virus RNA polymerase inhibitor. | Targeting viral polymerases has been a proven and attractive strategy for antiviral drug discovery. Herein we describe our effort in improving the antiviral activity and physical properties of a series of pounds as respiratory syncytial virus (RSV) RNA polymerase inhibitors. The antiviral activity and spectrum of this ... |
24211025 | Reduction of cognitive concerns of anxiety sensitivity is uniquely associated with reduction of PTSD and depressive symptoms: a comparison of civilians and veterans. | PTSD orbid depression mon among civilians and veterans, resulting in substantial impairment. Anxiety sensitivity (AS) may be mon malleable vulnerability factor for PTSD and depression. The AS cognitive concerns subscale is most strongly related to symptoms of PTSD and depression, and thus, may be an efficient route to ... |
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