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24211023 | Development and preliminary validation of a new scale to assess functional ability of older population in India. | Identifying the decline in functional ability and preventing disability is the critical element of the quality of life of an old age. However, the lack of contextual scale to assess the decline in functional capacity is a major issue. Objective of this study is to design the functional ability assessment scale for elde... |
24211026 | The use of antidepressant medication in pregnancy. | The use of antidepressant medications during pregnancy has stimulated much professional and public debate. As a consequence, considerable data on the reproductive safety of antidepressants has been generated that exceeds the available information for most, if not all, other classes of medications that may be used in th... |
24211027 | Longitudinal study of remission among older adults with schizophrenia spectrum disorder. | Although studies have found that as many as half of munity-dwelling adults with schizophrenia were in symptomatic remission, these findings had been based on cross-sectional data. This study examines longitudinal changes in symptom remission rates and predictors of remission. |
24211024 | Older person behavioral and psychological symptoms (BPS) and functional limitations mediate the association between older person cognitive impairment and depressive symptoms in the caregiver. | We assess for the mediation of the association between older person cognitive impairment and caregiver depressive symptoms through older person BPS and functional limitations, and whether the mediation varies by caregiver-older person relationship (spouse/adult child). Data for 1111 older person (aged 75+ with activity... |
24211028 | Depressive symptoms, symptom dimensions, and white matter lesion volume in older adults: a longitudinal study. | White matter lesions (WMLs) are associated with depressive symptoms in older adults. However, it is not clear whether different symptom dimensions of depression have distinct associations with WMLs. The authors assessed the longitudinal relationships of the Center for Epidemiologic Studies Depression Scale (CES-D) tota... |
24211029 | Increased risk among older veterans of prescribing psychotropic medication in the absence of psychiatric diagnoses. | This study uses Veterans Health Administration (VHA) pharmacy and encounter claims to evaluate the use of psychotropic medications without a psychiatric diagnosis across age groups. |
24211030 | Enantioseletive bioaccumulation and metabolization of diniconazole in earthworms (Eiseniafetida) in an artificial soil. | Degradation and enantioselective bioaccumulation of diniconazole in earthworms (Eiseniafetida) in artificial soil was investigated using liquid chromatography-tandem mass spectrometry (LC-MS/MS) method under laboratory condition. Three exposure concentrations (1 mg/kg, 10 mg/kg and 25 mg/kg) of diniconazole in soil (dr... |
24211031 | [Choice of career by French medical students after the national ranking exam in 2012]. | Since 2011, the French medical students ranked after a national ranking exam (NRE) are making their career choice among 11 disciplines detailing the chosen one. Before 2011, this precise choice was unknown. Our work is the first descriptive study of French medical students choice of career after the NRE, precising the ... |
24211032 | Building a picture: Prioritisation of exotic diseases for the pig industry in Australia using multi-criteria decision analysis. | Diseases that are exotic to the pig industry in Australia were prioritised using a multi-criteria decision analysis framework that incorporated weights of importance for a range of criteria important to industry stakeholders. Measurements were collected for each disease for nine criteria that described potential diseas... |
24211034 | Prevalence of restless legs syndrome in patients with chronic pain in Maputo, Mozambique. | Because there is only one study to our knowledge on the prevalence of restless legs syndrome (RLS) in sub-Saharan Africa and RLS is mon in patients with some pain syndromes, we aimed to determine the prevalence of RLS in a population with chronic pain in Maputo, Mozambique. |
24211035 | Screening for sleep dysfunction after traumatic brain injury. | Numerous studies on the high prevalence of sleep disorders in individuals with traumatic brain injury (TBI) have been conducted in the past few decades. These disorders can accentuate other consequences of TBI, negatively impacting mood, exacerbating pain, heightening irritability, and diminishing cognitive abilities a... |
24211036 | Whole-body MRI vs. CT for staging lymphoma: patient experience. | To assess pare patient experience of whole-body magnetic resonance imaging (MRI) to that puted tomography (CT) for staging newly diagnosed lymphoma. |
24211037 | Advanced computed tomographic anatomical and morphometric plaque analysis for prediction of fractional flow reserve in intermediate coronary lesions. | To determine the application of advanced puted tomography angiography (CCTA) plaque analysis for predicting invasive fractional flow reserve (FFR) in intermediate coronary lesions. |
24211038 | Purification, characterization, molecular cloning, and extracellular production of a novel bacterial glycerophosphocholine cholinephosphodiesterase from Streptomyces sanglieri. | A novel metal ion-independent glycerophosphocholine cholinephosphodiesterase (GPC-CP) of Streptomyces sanglieri was purified 53-fold from culture supernatant with 1.1% recovery (583 U/mg-protein). The enzyme functions as a monomer with a molecular mass of 66 kDa. The gene encoding the enzyme consists of a 1941-bp ORF t... |
24211040 | Reasons for rarity of Th17 cells in inflammatory sites of human disorders. | T helper 17 (Th17) cells have been reported to be responsible for several chronic inflammatory diseases. However, a peculiar feature of human Th17 cells is that they are very rare in the inflammatory sites parison with Th1 cells. The first reason for this rarity is the existence of some self-regulatory mechanisms that ... |
24211039 | The plasticity of human Treg and Th17 cells and its role in autoimmunity. | CD4(+) T helper cells are a central element of the adaptive immune system. They protect the organism against a wide range of pathogens and are able to initiate and control many immune reactions bination with other cells of the adaptive and the innate immune system. Starting from a naive cell, CD4(+) T cells can differe... |
24211041 | Induction and stability of the anergic phenotype in T cells. | One of the mechanisms that are in place to control the activation of mature T cells that bear self-reactive antigen receptors is anergy, a long-term state of hyporesponsiveness that is established in T cells in response to suboptimal stimulation. T cells receive signals that result not only from antigen recognition and... |
24211045 | Coincidental vascular anomalies at the foramen magnum: dural arteriovenous fistula and high flow aneurysm on perimedullary fistula. | We report the case of a 59-year-old woman admitted for a sudden headache due to a subarachnoid haemorrhage. On CT scan, the clots predominated into the posterior fossa without high-density in the sylvian or interhemispheric fissures. The vertebral angiography revealed a dural arteriovenous fistula at the foramen magnum... |
24211046 | Detection of anti-Leishmania infantum antibodies in sylvatic lagomorphs from an epidemic area of Madrid using the indirect immunofluorescence antibody test. | An outbreak of human leishmaniasis was confirmed in the southwest of the province of Madrid, Spain, between July 2009 and December 2012. Incidence of Leishmania infection in dogs was unchanged in this period, prompting a search for alternative sylvatic infection reservoirs. We evaluated exposure to Leishmania in serum ... |
24211047 | Factors affecting stress experienced by surrogate decision makers for critically ill patients: implications for nursing practice. | This study explores surrogate decision-makers' (SDMs) challenges making decisions related to the care of patients in critical care, to (1) characterise the SDM stress, (2) identify personal, social, care-related factors influencing stress and (3) consider implications of findings to improving critical care practice. |
24211048 | Providing critical care patients with a personalised discharge summary: a questionnaire survey and retrospective analysis exploring feasibility and effectiveness. | This paper reports on the potential value and feasibility of providing patients with a personalised discharge summary of their critical care stay. |
24211049 | Attitudes of legal guardians in the ICU - a qualitative report. | Decision-making in intensive care units (ICUs) is often made by surrogates, since patients are unconscious or petent. In Israel, Legal Guardians (LGs), appointed by the court, are required to make these decisions. |
24211051 | Gastrocnaemius-propeller extended miocutanous flap: a new chimaeric flap for soft tissue reconstruction of the knee. | Soft tissue defects involving the anterior aspect of the knee are a frequent finding in a number of pathological conditions. The aim of this article is to describe a new pedicled flap consisting of a conventional medial gastrocnaemius muscle flap associated with a propeller flap based on a perforator of the medial sura... |
24211052 | Aspirin resistant patients with recent ischemic stroke. | Some patients with a recent ischemic stroke who are being treated with aspirin as an antiaggregant suffer a new ischemic stroke. These patients (15-25%) have been called unresponsive to aspirin or aspirin resistant. The aspirin-resistant patients have a four-time greater risk of suffering a stroke. Furthermore, these s... |
24211053 | A simple method minimizes chylothorax after minimally invasive esophagectomy. | Postoperative chylothorax is a rare, but potentially plication after esophagectomy. Preventive measures aimed at decreasing the incidence of chyle leakage after minimally invasive esophagectomy (MIE) could potentially reduce the high postoperative mortality associated with plication. However, previous techniques are tr... |
24211054 | Effect of preoperative renal insufficiency on postoperative outcomes after pancreatic resection: a single institution experience of 1,061 consecutive patients. | Chronic kidney disease (CKD) is known to adversely affect cardiac and vascular surgery es. We examined the effect of preoperative renal insufficiency on postoperative es after pancreatic resection. |
24211057 | Total joint arthroplasty and preoperative low back pain. | Lower extremity osteoarthritis with itant low-back pain (LBP) may obscure a clinician's ability to properly evaluate the status of hip or knee osteoarthritis and subsequent total joint arthroplasty (TJA) candidacy. A prospective cohort study was conducted to determine prevalence and severity of preoperative LBP among T... |
24211058 | Concomitant therapy in people with epilepsy: potential drug-drug interactions and patient awareness. | People with epilepsy (PWE) may use prescription and over-the-counter (OTC) drugs for the treatment of itant diseases. Combinations of these drugs, as well as dietary supplements, with antiepileptic drugs (AEDs) may lead to reduced control of seizures and of coexisting medical conditions and increased risk of adverse dr... |
24211060 | CYP2D6 phenotypes and Parkinson's disease risk: a meta-analysis. | CYP2D6 polymorphisms have been reported to be associated with Parkinson's disease (PD) susceptibility, but the results of these previous studies were inconsistent. |
24211059 | Effect of cilostazol in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. | Previous studies with small sample size have shown that cilostazol can reduce the risk of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage (SAH). The purpose of this study was to determine whether cilostazol is effective in patients with aneurysmal SAH. Studies investigating the effect of cilostaz... |
24211061 | Central nervous system vasculitis associated with hepatitis C virus infection: a brain MRI-supported diagnosis. | The Hepatitis C virus (HCV) infection is associated with various extrahepatic manifestations, being the Central Nervous System (CNS) rarely involved. |
24211062 | Chronic migraine does not increase posterior circulation territory (PCT) infarct-like lesions. | Two population-based studies have found an increased prevalence of posterior circulation territory (PCT) infarct-like lesions in migraine, which seemed to increase with attack frequency. |
24211063 | Relationships between ophthalmic artery flow direction and cognitive performance in patients with unilateral carotid artery stenosis. | Cerebral hypoperfusion is responsible for cognitive impairment in patients with severe carotid artery stenosis (CAS). The manifestation of reversed ophthalmic artery flow (ROAF) is not mon in patients with CAS, suggesting a state of intensified cerebral hypoperfusion. This study aimed to examine whether the presence of... |
24211064 | High risks of all-cause and cardiovascular deaths in apparently healthy middle-aged people with preserved glomerular filtration rate and albuminuria: A prospective cohort study. | The reason why coexistence of preserved estimated glomerular filtration rate (eGFR) and albuminuria contributes to a high risk of death and which cause of death increases all-cause mortality have not been elucidated. |
24211065 | Proximal coronary artery intervention: stent thrombosis, restenosis and death. | Percutaneous coronary intervention (PCI) of lesions in the proximal left anterior descending coronary artery (LAD) may confer a worse pared with the proximal right coronary artery (RCA) and left circumflex coronary artery (LCX). |
24211066 | Autotransplantation of mesenchymal stromal cells from bone-marrow to heart in patients with severe stable coronary artery disease and refractory angina--final 3-year follow-up. | The study assessed long-term safety and efficacy of intramyocardial injection of autologous bone-marrow derived mesenchymal stromal cells (BMMSCs) in patients with severe stable coronary artery disease (CAD) and refractory angina. |
24211070 | Influence of population versus convenience sampling on sample characteristics in studies of cognitive aging. | We examined whether differences in findings of studies examining mild cognitive impairment (MCI) were associated with recruitment methods paring sample characteristics in two contemporaneous Australian studies, using population-based and convenience sampling. |
24211071 | Reference values for respiratory events in overnight polygraphy from infants aged 1 and 3months. | We aimed to determine reference values for respiratory indices in polygraphies (PGs) performed in infants aged 1 and 3months. |
24211069 | Gene expression patterns in wheat coleorhiza under cold- and biological stratification. | This study assessed germination of wheat seeds under cold and biological stratification and determined the expression level of gibberellins (GA) and abscisic acid (ABA) genes in coleorhiza. Both cold and biological stratification significantly (P<0.05) enhanced the rate and efficacy of germination. The spatial distance... |
24211073 | Determination of anti-Müllerian hormone at estrus during a synchronized and a natural bovine estrous cycle. | Anti-Müllerian hormone (AMH) has been correlated with phenotypic indicators of fertility. However, the effects of exogenous hormones used during estrus synchronization on AMH have not been evaluated. Therefore, the objective of this experiment was to determine whether concentrations of AMH at estrus are similar between... |
24211072 | Nonapnea sleep disorders are associated with subsequent ischemic stroke risk: a nationwide, population-based, retrospective cohort study. | Obstructive sleep apnea (OSA) is related to an increased risk for stroke and cardiovascular disease. However, studies investigating the relationship between nonapnea sleep disorders (NSD) and the risk for subsequent ischemic stroke are scant. The objective of our study was to assess the association between NSD and the ... |
24211068 | [Scales to evaluate pain in elderly patients suffering from dementia. Help-tools for the physiotherapist, doctor, nurse and occupational therapist]. | The purpose of this study was to determine which scales are being used to evaluate pain in old people suffering from dementia. A search strategy was developed to retrieve all articles (randomized controlled trials and clinical trials without randomization) published in MEDLINE, Cochrane Library Plus, PEDro and Dialnet ... |
24211074 | Particle retention in suspension-feeding fish after removal of filtration structures. | The suspension-feeding cichlids Oreochromis aureus (blue tilapia) and Oreochromis esculentus (ngege tilapia) are able to selectively retain small food particles. The gill rakers and microbranchiospines of these species have been assumed to function as filters. However, surgical removal of these oral structures, which a... |
24211075 | A cationic cholesterol based nanocarrier for the delivery of p53-EGFP-C3 plasmid to cancer cells. | The p53 protein mediated anti-tumor strategy is limited due to the lack of suitable delivery agent with insignificant immunogenic response, patibility, and early and easy detection of the transfected cell population. To e these problems, we generated a p53-EGFP-C3 fusion construct which expressed easily detectable gree... |
24211076 | Controlling stem cell-mediated bone regeneration through tailored mechanical properties of collagen scaffolds. | Mechanical properties of the extracellular matrix (ECM) play an essential role in cell fate determination. To study the role of mechanical properties of ECM in stem cell-mediated bone regeneration, we used a 3D in vivo ossicle model that recapitulates endochondral bone formation. Three-dimensional gelatin scaffolds wit... |
24211077 | A review of polypeptide-based polymersomes. | Self-assembled systems from biodegradable amphiphilic polymers at the nanometer scale, such as nanotubes, nanoparticles, polymer micelles, nanogels, and polymersomes, have attracted much attention especially in biomedical fields. Among these nano-aggregates, polymersomes have attracted tremendous interests as versatile ... |
24211078 | A systems toxicology approach to the surface functionality control of graphene-cell interactions. | The raised considerable concerns about the possible environmental health and safety impacts of graphene nanomaterials and their derivatives originated from their potential widespread applications. We performed prehensive study about biological interaction of grapheme nanomaterials, specifically in regard to its differe... |
24211079 | Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma. | Glioblastoma-targeted drug delivery systems facilitate efficient delivery of chemotherapeutic agents to malignant gliomas, while minimizing systemic toxicity and side effects. Taking advantage of the fibrin deposition that is characteristic of tumors, we constructed spherical, Cy7-labeled, targeting micelles to gliobla... |
24211080 | Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting. | The application of non-viral gene delivery vectors is often panied with the poor correlation between transfection efficiency and the safety profiles of vectors. Vectors with high transfection efficiencies often suffer from high toxicities, making it unlikely to improve their efficiencies by increasing the DNA dosage. I... |
24211081 | Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic β-sheet forming peptide amphiphiles. | In the face of mounting global antibiotics resistance, the identification and development of membrane-active antimicrobial peptides (AMPs) as an alternative class of antimicrobial agent have gained significant attention. The physical perturbation and disruption of microbial membranes by the AMPs have been proposed to b... |
24211082 | Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake. | Porous silicon (PSi) has been demonstrated as a promising drug delivery vector for poorly water-soluble drugs. Here, a simple and efficient method based on copper-free click chemistry was used to introduce targeting moieties to PSi nanoparticles in order to enhance the intracellular uptake and tumor specific targeting ... |
24211083 | Air-bone gap in ears with a well-repaired tympanic membrane after Type III and Type IV tympanoplasty. | To investigate the air-bone conduction hearing gap (A-B gap) after Type III and Type IV stapes columella tympanoplasty in ears with mobile stapes and a well repaired tympanic membrane (TM). |
24211084 | Distant metastasis in p16-positive oropharyngeal squamous cell carcinoma: a critical analysis of patterns and outcomes. | With good loco-regional control, disease failure in p16-positive oropharyngeal squamous cell carcinoma (OPSCC) mainly results from distant metastasis (DM). Our objective was to characterize the patterns and clinical es of DM in p16-positive OPSCC pare these to patients with p16-negative disease. |
24211085 | Hyperactivity and impulsivity in children with untreated allergic rhinitis: corroborated by rating scale and continuous performance test. | Allergic rhinitis (AR) is the mon chronic allergic disease in school-age children. An increased prevalence of attention deficit hyperactivity disorder (ADHD) in AR patients has been reported; however, inattention and hyperactivity in AR children have not been investigated using objective and scientific measurements. |
24211086 | Asthma exacerbation in children: a practical review. | Asthma is the mon chronic lower respiratory tract disease in childhood throughout the world. Despite advances in asthma management, acute exacerbations continue to be a major problem in patients and they result in a considerable burden on direct/indirect health care providers. A severe exacerbation occurring within 1 y... |
24211089 | Loads on a vertebral body replacement during locomotion measured in vivo. | Walking is one of the most important activities in daily life, and walking exposes the spine to a high number of loading cycles. Little is known about the spinal loads during walking. Telemeterized spinal implants can provide data about their loading during different activities. The aim of this study was to measure the... |
24211088 | Characterisation of SCCmec elements in methicillin-resistant Staphylococcus aureus isolated from burn patients. | Staphylococcus aureus is an important pathogen, especially in burn units all around the world. Because of the emergence of the β-lactam antibiotic-resistant strains since 1961, concern about the prevalence of methicillin-resistant S. aureus (MRSA) has increased in these units. Resistance to methicillin is mediated by p... |
24211092 | [Medical students and drug marketing]. | To determine the exposure of medical students to the marketing activities of the pharmaceutical industry, and identify their opinions and attitudes, and also the possible effects this exposure on their training and future professional practice. |
24211090 | The relative associations of β-cell function and insulin sensitivity with glycemic status and incident glycemic progression in migrant Asian Indians in the United States: the MASALA study. | We assessed the relative associations of β-cell dysfunction and insulin sensitivity with baseline glycemic status and incident glycemic progression among Asian Indians in the United States. |
24211091 | The economic burden of progressive chronic kidney disease among patients with type 2 diabetes. | To estimate the rate of progression of chronic kidney disease (CKD) among patients with type 2 diabetes (T2D) and calculate medical costs associated with progression. |
24211094 | WT1 isoform expression pattern in acute myeloid leukemia. | WT1 plays a dual role in leukemia development, probably due to an imbalance in the expression of the 4 main WT1 isoforms. We quantify their expression and evaluate them in a series of AML patients. Our data showed a predominant expression of isoform D in AML, although in a lower quantity than in normal CD34+ cells. We ... |
24211095 | Arsenic trioxide induces apoptosis in B-cell chronic lymphocytic leukemic cells through down-regulation of survivin via the p53-dependent signaling pathway. | Arsenic trioxide (As2O3) can induce apoptosis in many tumors. However, the associated mechanisms are not clearly understood. We found that As2O3 significantly inhibited the proliferation of WSU-CLL cells and induced apoptosis in dose- and time-dependent manners. WSU-CLL cells treated with 2μM As2O3 showed survivin down... |
24211097 | A predictive model of complications after spine surgery: the National Surgical Quality Improvement Program (NSQIP) 2005-2010. | There is increasing scrutiny by several regulatory bodies regarding plications of spine surgery. Precise delineation of the risks contributing to plications remains a topic of debate. |
24211098 | Adult thoracolumbar and lumbar scoliosis treated with long vertebral fusion to the sacropelvis: a comparison between new hybrid selective spinal fusion versus anterior-posterior spinal instrumentation. | Combined anteroposterior spinal fusion with instrumentation has been used for many years to treat adult thoracolumbar/lumbar scoliosis. This surgery remains a technical challenge to spine surgeons, and current literature reports plication rates. |
24211099 | Early postoperative fear of movement predicts pain, disability, and physical health six months after spinal surgery for degenerative conditions. | The fear-avoidance model offers a promising framework for understanding the development of chronic postoperative pain and disability. However, limited research has examined this model in patients undergoing spinal surgery. |
24211096 | Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. | Tobacco smoking is a key risk factor for spine degeneration. However, the underlying mechanism by which smoking induces degeneration is not known. Recent studies implicate DNA damage as a cause of spine and intervertebral disc degeneration. Because tobacco smoke contains many genotoxins, we hypothesized that tobacco sm... |
24211100 | Changes in metal contamination levels in estuarine sediments around India--an assessment. | This review is the first attempt prehend the changes in metal contamination levels in surface estuarine sediments with changing time around India. Contamination factor, geoaccumulation index, pollution load index, effects range low and effects range median analysis were used to evaluate the quality of the estuarine sed... |
24211101 | Impact of environmental pollution on caged mussels Mytilus galloprovincialis using NMR-based metabolomics. | Metabolic responses to environmental pollution, mainly related to Hg and PAHs, were investigated in mussels. Specimens of Mytilus galloprovincialis, sedentary filter-feeders, were caged in anthropogenic-impacted and reference sites along the Augusta coastline (Sicily, Italy). The gills, mainly involved in nutrient upta... |
24211102 | Neurovascular quantitative study of the uterosacral ligament related to nerve-sparing radical hysterectomy. | To analyze the distribution of autonomic nerves and blood and lymphatic vessels in the uterosacral ligament, elucidate detailed anatomy at a surgical level and provide pathobiological evidence for improvement of nerve-sparing radical hysterectomy. |
24211103 | Effects of monitoring strategies on seizures in pregnant women on lamotrigine: a meta-analysis. | Pregnant women with epilepsy have a significantly increased risk of mortality and pared to non-pregnant women. At least one in 250 pregnancies is exposed to anti-epileptic drugs (AED). Seizure deterioration occurs in up to a third of pregnant women. AED levels fall in most pregnant women, although it is uncertain that ... |
24211106 | Identifying and measuring stakeholder preferences for disease prioritisation: A case study of the pig industry in Australia. | We describe stakeholder preference modelling using bination of new and recently developed techniques to elicit criterion weights to incorporate into a multi-criteria decision analysis framework to prioritise exotic diseases for the pig industry in Australia. Australian pig producers were requested to rank disease prisi... |
24211105 | Evaluation of the benefit of emergency vaccination in a foot-and-mouth disease free country with low livestock density. | Foot-and-mouth disease (FMD) is highly contagious and one of the most economically devastating diseases of cloven-hoofed animals. Scientific-based preparedness about how to best control the disease in a previously FMD-free country is therefore essential for veterinary services. The present study used a spatial, stochas... |
24211104 | Observed changes in first metatarsal and medial cuneiform positions after first metatarsophalangeal joint arthrodesis. | The first intermetatarsal angle (IMA) is known to decrease after first metatarsophalangeal joint arthrodesis, although the exact mechanism by which this decrease occurs is not known. We measured the first IMA and obliquity of the medial cuneiform on anteroposterior weightbearing preoperative and postoperative radiograp... |
24211108 | [Is a patient's knowledge of cardiovascular risk factors better after the occurrence of a major ischemic event? Survey of 135 cases and 260 controls]. | We hypothezised that patients (cases) who are hospitalized for a major ischemic event--myocardial infarction, stroke, pensation of peripheral arterial disease--acquire better knowledge than a control population--atheromatous patients without a major ischemic event, patients consulting for a vein disease or a diabetes e... |
24211109 | Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice. | Myeloproliferative neoplasms constitute a group of hematopoietic neoplasms at the myeloid stem cell level. Although mutations in the receptor tyrosine kinase KIT have been identified in patients with myeloproliferative neoplasm, the functional causality is unknown because of a lack of animal models. Here, we describe a... |
24211110 | Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation. | Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor-suppressor gene, which encodes neurofibromin, a negative regulator of diverse Ras signaling cascades. Arterial stenosis is a nonneoplastic manifestation of NF1 that predisposes some patients to debilitating morbidity and sudden death. Recent murine ... |
24211111 | Pulmonary endothelial protein kinase C-delta (PKCδ) regulates neutrophil migration in acute lung inflammation. | Excessive neutrophil migration across the pulmonary endothelium into the lung and release of oxidants and proteases are key elements in pathogenesis of acute lung injury. Previously, we identified protein kinase C-delta (PKCδ) as an important regulator of proinflammatory signaling in human neutrophils and demonstrated ... |
24211113 | Postoperative patency of the retrograde internal mammary vein anastomosis in free flap transfer. | A caudal limb of the internal mammary vein (IMV) can be used as an additional venous drainage route in free flap transfer. However, there remains the possibility that unrecognised occlusion of the retrograde IMV occurs in the early postoperative period due to non-physiologic flow, thus affecting venous drainage. There ... |
24211114 | Nasalance scores for normal Korean-speaking adults and children. | There are numerous nasometric studies to date, including normative nasalance scores for various languages as well as nasometric differences in age, gender, race and region except the Korean language. In this regard, we sought to establish normative nasalance scores for Koreans. We created speech samples based on the ev... |
24211107 | Toxicity of the micropollutants Bisphenol A, Ciprofloxacin, Metoprolol and Sulfamethoxazole in water samples before and after the oxidative treatment. | The amount of organic micropollutants detected in surface waters increases steadily. Common waste water treatment plants are not built to remove these substances. Thus there is a need for new technologies. A promising technology is the use of advanced oxidation processes through which organic micropollutants can be rem... |
24211115 | The use of a microscope with near-infrared imaging function in indocyanine green lymphography and lymphaticovenous anastomosis. | Indocyanine green (ICG) lymphography has e an important investigation in lymphaticovenous anastomosis (LVA). Near-infrared (NIR) imaging systems are available in the market for the production of ICG lymphography. These machines, however, may be difficult to obtain owing to their costs. In our institute, these NIR imagi... |
24211116 | Shoulder silhouette and axilla reconstruction with free composite elbow tissue transfer following interscapulothoracic amputation. | Interscapulothoracic amputation (ISTA) passes the removal of the upper limb, scapula and clavicle. As the reconstructive and oncologic limb-saving techniques improved, the indications for this formidable procedure decreased. However, it is still the appropriate procedure in cases with extensive oncologic or traumatic i... |
24211117 | Multiple-digit resurfacing using a thin latissimus dorsi perforator flap. | Traumatic digit defects of plexity and with inadequate local tissue represent challenging surgical problems. Recently, perforator flaps have been proposed for reconstructing large defects of the hand because of their thinness and pliability and minimal donor site morbidity. Here, we illustrate the use of thin latissimu... |
24211118 | Complications following body contouring surgery after massive weight loss: a meta-analysis. | Bariatric surgery is a way to achieve lasting weight loss in the obese. Body contouring surgery seeks to alleviate some of the fort caused by the excessive loose skin following massive weight loss. plication rates are described in this type of surgery when done post-bariatric. The purpose of this article is plication r... |
24211120 | The mechanics behind cell division. | It is now well established that the orientation of the plane of cell division highly depends on cell geometry in plants. However, the related molecular mechanism remains largely unknown. Recent data in animal systems highlight the role of the cytoskeleton response to mechanical stress in this process. Interestingly, th... |
24211112 | A pilot test of an integrated self-care intervention for persons with heart failure and concomitant diabetes. | Studies show 30% to 47% of people with heart failure (HF) have itant diabetes mellitus (DM). Self-care for persons with both of these chronic conditions is plex, and often inadequate. This pilot study tested an integrated self-care program for its effects on HF and DM knowledge, self-care efficacy, self-care behaviors,... |
24211124 | Correlates of emotional congruence with children in sexual offenders against children: a test of theoretical models in an incarcerated sample. | Emotional congruence with children is a psychological construct theoretically involved in the etiology and maintenance of sexual offending against children. Research conducted to date has not examined the relationship between emotional congruence with children and other psychological meaningful risk factors for sexual ... |
24211125 | Histological characteristics of induced membranes in subcutaneous, intramuscular sites and bone defect. | The induced membrane technique was proposed as a treatment of large segmental bone defects. The influence of the surrounding tissues on its characteristics remains unknown. It is therefore not known which kind of plastic surgery procedure (muscular or facio-cutaneous flap) would optimize bone osteointegration within a ... |
24211122 | Dosimetric and clinical outcome in image-based high-dose-rate interstitial brachytherapy for anal cancer. | To evaluate dosimetric and clinical e in patients of anal cancer treated with image-based interstitial high-dose-rate brachytherapy following chemoradiation. |
24211123 | Re-irradiation with interstitial pulsed-dose-rate brachytherapy for unresectable recurrent head and neck carcinoma. | To assess the long-term results of protocol-based interstitial pulsed-dose-rate (PDR) bined with simultaneous chemotherapy in selected patients with recurrent head and neck tumors not amenable to salvage surgery. |
24211126 | Isolated anterior interosseous nerve deficit due to a false aneurysm of the humeral artery: an unusual complication of penetrating arm injury. Case report and literature review. | Anterior interosseous nerve (AIN) injuries account for only 1% of all the nerve injuries at the upper limb. We report the case of a 22-year-old male who sustained a penetrating injury to the arm. No neurological deficit was found at the initial evaluation. However, 6 weeks later, he had a motor deficit confined to the ... |
24211127 | High rate of fracture in the cementless modular Extrême™ (Mark I) femoral prosthesis in revision total hip arthroplasty: 33 cases at more than 5 years' follow-up. | The modular concept has been mended in femoral revision surgery with extensive bone loss, but entails plications: disassembly and fracture. The present retrospective study assessed the Mark I Extrême™ modular prosthesis at a minimum 5 years' follow-up. |
24211128 | Rotator cuff tears after 70 years of age: a prospective, randomized, comparative study between decompression and arthroscopic repair in 154 patients. | Arthroscopic repair of rotator cuff tears leads to better clinical es than subacromial pression alone; however the former is rarely proposed to patients above 70 years of age. Our hypothesis was that arthroscopic repair would be superior to pression in patient 70 years or older. The primary goal was pare the clinical r... |
24211129 | Rotator cuff tear imaging in patients over 70 years: specific MRI findings? | During the symposium held by the French Arthroscopy Society on rotator cuff tears in patients over 70 years of age, the absence of studies into potential specific pathological features in this age group was pointed out. Here, our main objective was to describe magnetic resonance imaging (MRI) findings in this patient p... |
24211131 | Frequency of acute worsening events in fibrotic pulmonary sarcoidosis patients. | Patients with fibrotic sarcoidosis can develop worsening of pulmonary symptoms for various reasons. We studied acute worsening events defined as episodes treated with limited courses of either antibiotics and or increased corticosteroid doses which resolved within four weeks. The prevalence of acute worsening events in... |
24211132 | Chenopodolans A-C: phytotoxic furopyrans produced by Phoma chenopodiicola, a fungal pathogen of Chenopodium album. | Three tetrasubstituted furopyrans, named chenopodolans A-C, were isolated together with the well known fungal metabolite (-)-(R)-6-hydroxymellein from the liquid culture of Phoma chenopodiicola, a fungal pathogen proposed for the biological control of Chenopodium album, mon worldwide weed of arable crops. The structure... |
24211133 | Interrater reliability assessment using the Test of Gross Motor Development-2. | The aim was to examine interrater reliability of the object control subtest from the Test of Gross Motor Development-2 by live observation in a school field setting. |
24211134 | [Recognition of excretory/secretory antigens of Anisakis type I and evolution of IgE in experimentally infected rats]. | Anisakis spp., during parasitism, release excretory-secretory antigens that, in contact with the human immune system, can trigger a hypersensitivity response mediated by IgE, causing various allergic symptoms. |
24211136 | PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models. | Phosphoinositide-3 kinase (PI3K)-δ and PI3K-γ are preferentially expressed in immune cells, and inhibitors targeting these isoforms are hypothesized to have anti-inflammatory activity by affecting the adaptive and innate immune response. We report on a potent oral PI3K-δ and PI3K-γ inhibitor (IPI-145) and characterize ... |
24211137 | Crystal structures of Sirt3 complexes with 4'-bromo-resveratrol reveal binding sites and inhibition mechanism. | Sirtuins are protein deacetylases regulating aging processes and various physiological functions. Resveratrol, a polyphenol found in red wine, activates human Sirt1 and inhibits Sirt3, and it can mimic calorie restriction effects, such as lifespan extension in lower organisms. The mechanism of Sirtuin modulation by res... |
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