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Remove non-LFS code/config files, keep only binary data

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  1. data/cube_model/depthplot/bin_indices.csv +0 -0
  2. data/cube_model/depthplot/boutons.csv +0 -40
  3. data/cube_model/depthplot/depths.csv +0 -40
  4. data/cube_model/empirical_data_2020-07-13.json +0 -1
  5. data/structural_model/empirical_data_2020-07-13.json +0 -1
  6. data/structural_model/inference_experiments_local.json +0 -24
  7. data/subcellular_features/empirical_data_2020-07-13.json +0 -1
  8. data/subcellular_features/inference_experiments_local.json +0 -31
  9. figures/fig3/figure3-sbi_with_measurements.ipynb +0 -0
  10. figures/fig4-5/figure4-sbi_with_rule_variants.ipynb +0 -0
  11. figures/plotting_settings.mplstyle +0 -12
  12. figures/plotting_utils.py +0 -72
  13. figures/supplementary_figures/plotting_settings.mplstyle +0 -12
  14. figures/supplementary_figures/supp_fig1_sbi_benchmark.ipynb +0 -0
  15. figures/supplementary_figures/supp_fig2-3_predictives_and_conditionals.ipynb +0 -0
  16. figures/supplementary_figures/supp_fig4_prior_predictive.ipynb +0 -0
  17. figures/supplementary_figures/supp_fig5-two_param_DSO_rule.ipynb +0 -0
  18. results/benchmark_poisson_glm_snpe_samples/.hydra/config.yaml +0 -24
  19. results/benchmark_poisson_glm_snpe_samples/.hydra/hydra.yaml +0 -142
  20. results/benchmark_poisson_glm_snpe_samples/.hydra/overrides.yaml +0 -5
  21. results/benchmark_poisson_glm_snpe_samples/log_prob_true_parameters.csv +0 -1
  22. results/benchmark_poisson_glm_snpe_samples/metrics.csv +0 -2
  23. results/benchmark_poisson_glm_snpe_samples/num_simulations_simulator.csv +0 -1
  24. results/benchmark_poisson_glm_snpe_samples/posterior_samples.csv.bz2 +0 -3
  25. results/benchmark_poisson_glm_snpe_samples/predictive_samples.csv.bz2 +0 -3
  26. results/benchmark_poisson_glm_snpe_samples/run.yaml +0 -24
  27. results/benchmark_poisson_glm_snpe_samples/runtime.csv +0 -1
  28. results/benchmark_poisson_glm_snpe_samples/sbi-logs/SNPE_C/2021-01-15T15_40_58.032206/events.out.tfevents.1610721658.sbi.3935642.3 +0 -3
  29. results/npe_dso_two_param_uniform_200000 +0 -3
data/cube_model/depthplot/bin_indices.csv DELETED
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data/cube_model/depthplot/boutons.csv DELETED
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data/cube_model/empirical_data_2020-07-13.json DELETED
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"authors": "H Markram, J L\u00fcbke, M Frotscher, A Roth, B Sakmann", "title": "Physiology and Anatomy of Synaptic Connections Between Thick Tufted Pyramidal Neurones in the Developing Rat Neocortex", "journal": "J Physiol. 1997 Apr 15;500 ( Pt 2)(Pt 2):409-40.", "year": "1997", "DOI": "10.1113/jphysiol.1997.sp022031", "PMID": "9147328", "pre_layer": "L5", "pre_type": "EXC", "post_layer": "L5", "post_type": "EXC", "only_septum": "no", "cp_empirical": 10, "species": "rat", "area": "SS", "samples": 500}, {"ID": "ae04d7f5-5c09-4d3a-a0c8-994d1b9b2b98", "type": "connection_probability_invitro", "authors": "Audrey Mercer, David C West, Oliver T Morris, Sarah Kirchhecker, Jane E Kerkhoff, Alex M Thomson", "title": "Excitatory Connections Made by Presynaptic Cortico-Cortical Pyramidal Cells in Layer 6 of the Neocortex", "journal": "Cereb Cortex. 2005 Oct;15(10):1485-96.", "year": "2005", "DOI": "10.1093/cercor/bhi027", "PMID": "15647524", "pre_layer": "L6", "pre_type": "EXC", "post_layer": "L6", "post_type": "EXC", "only_septum": "no", "cp_empirical": 4, "species": "rat", "area": "SS, VS", "samples": 27}, {"ID": "8cb7701b-ed14-4743-9ba3-d4a84d3b585d", "type": "connection_probability_invitro", "authors": "Rodrigo Perin, Thomas K Berger, Henry Markram", "title": "A Synaptic Organizing Principle for Cortical Neuronal Groups", "journal": "Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5419-24.", "year": "2011", "DOI": "10.1073/pnas.1016051108", "PMID": "21383177", "pre_layer": "L5", "pre_type": "L5PT", "post_layer": "L5", "post_type": "L5PT", "only_septum": "no", "cp_empirical": 13, "species": "rat", "area": "SS", "samples": 3446}, {"ID": "107c2b45-4df2-4311-a007-38b40756aa63", "type": "connection_probability_invitro", "authors": "Carl C H Petersen, Bert Sakmann", "title": "The Excitatory Neuronal Network of Rat Layer 4 Barrel Cortex", "journal": "J Neurosci. 2000 Oct 15;20(20):7579-86.", "year": "2000", "DOI": "10.1523/JNEUROSCI.20-20-07579.2000", "PMID": "11027217", "pre_layer": "L4", "pre_type": "L4ss", "post_layer": "L4", "post_type": "L4ss", "only_septum": "no", "cp_empirical": 36, "species": "rat", "area": "barrel", "samples": 146}, {"ID": "745d65c1-5831-4bb9-b28c-619e5893b3a7", "type": "connection_probability_invitro", "authors": "Gilad Silberberg, Henry Markram", "title": "Disynaptic Inhibition Between Neocortical Pyramidal Cells Mediated by Martinotti Cells", "journal": "Neuron. 2007 Mar 1;53(5):735-46.", "year": "2007", "DOI": "10.1016/j.neuron.2007.02.012", "PMID": "17329212", "pre_layer": "L5", "pre_type": "EXC", "post_layer": "L5", "post_type": "EXC", "only_septum": "no", "cp_empirical": 12, "species": "rat", "area": "SS", "samples": 1450}, {"ID": "2a01488f-6fba-4efc-bbdb-9a50a4bf003d", "type": "connection_probability_invitro", "authors": "Sen Song, Per Jesper Sj\u00f6str\u00f6m, Markus Reigl, Sacha Nelson, Dmitri B Chklovskii", "title": "Highly Nonrandom Features of Synaptic Connectivity in Local Cortical Circuits", "journal": "PLoS Biol. 2005 Mar;3(3):e68.", "year": "2005", "DOI": "10.1371/journal.pbio.0030068", "PMID": "15737062", "pre_layer": "L5", "pre_type": "L5PT", "post_layer": "L5", "post_type": "L5PT", "only_septum": "no", "cp_empirical": 12, "species": "rat", "area": "VC", "samples": 8050}, {"ID": "dabe08c5-2260-40eb-ab2a-585446ee7615", "type": "connection_probability_invitro", "authors": "Qian-Quan Sun, John R Huguenard, David A Prince", "title": "Barrel Cortex Microcircuits: Thalamocortical Feedforward Inhibition in Spiny Stellate Cells Is Mediated by a Small Number of Fast-Spiking Interneurons", "journal": "J Neurosci. 2006 Jan 25;26(4):1219-30.", "year": "2006", "DOI": "10.1523/JNEUROSCI.4727-04.2006", "PMID": "16436609", "pre_layer": "L4", "pre_type": "L4sp", "post_layer": "L4", "post_type": "L4sp", "only_septum": "no", "cp_empirical": 21, "species": "rat", "area": "barrel", "samples": 24}, {"ID": "e1302174-b50c-4f7f-bafb-993fd7c9a678", "type": "connection_probability_invitro", "authors": "Qian-Quan Sun, John R Huguenard, David A Prince", "title": "Barrel Cortex Microcircuits: Thalamocortical Feedforward Inhibition in Spiny Stellate Cells Is Mediated by a Small Number of Fast-Spiking Interneurons", "journal": "J Neurosci. 2006 Jan 25;26(4):1219-30.", "year": "2006", "DOI": "10.1523/JNEUROSCI.4727-04.2006", "PMID": "16436609", "pre_layer": "L4", "pre_type": "L4ss", "post_layer": "L4", "post_type": "L4ss", "only_septum": "no", "cp_empirical": 21, "species": "rat", "area": "barrel", "samples": 24}, {"ID": "3410f9b8-f11a-49c2-b033-f63eb98b2dc9", "type": "connection_probability_invitro", "authors": "Alex M Thomson, David C West, Yun Wang, A Peter Bannister", "title": "Synaptic Connections and Small Circuits Involving Excitatory and Inhibitory Neurons in Layers 2-5 of Adult Rat and Cat Neocortex: Triple Intracellular Recordings and Biocytin Labelling in Vitro", "journal": "Cereb Cortex. 2002 Sep;12(9):936-53.", "year": "2002", "DOI": "10.1093/cercor/12.9.936", "PMID": "12183393", "pre_layer": "L23", "pre_type": "EXC", "post_layer": "L23", "post_type": "EXC", "only_septum": "no", "cp_empirical": 26, "species": "rat", "area": "SM", "samples": 247}, {"ID": "a0e90a58-2fa3-4f0c-a024-76ff113b4f13", "type": "connection_probability_invitro", "authors": "Alex M Thomson, David C West, Yun Wang, A Peter Bannister", "title": "Synaptic Connections and Small Circuits Involving Excitatory and Inhibitory Neurons in Layers 2-5 of Adult Rat and Cat Neocortex: Triple Intracellular Recordings and Biocytin Labelling in Vitro", "journal": "Cereb Cortex. 2002 Sep;12(9):936-53.", "year": "2002", "DOI": "10.1093/cercor/12.9.936", "PMID": "12183393", "pre_layer": "L3", "pre_type": "EXC", "post_layer": "L5", "post_type": "EXC", "only_septum": "no", "cp_empirical": 55, "species": "rat", "area": "SM", "samples": 29}, {"ID": "459f83ca-9039-4f30-8952-79fa7f0c259b", "type": "connection_probability_invitro", "authors": "Alex M Thomson, David C West, Yun Wang, A Peter Bannister", "title": "Synaptic Connections and Small Circuits Involving Excitatory and Inhibitory Neurons in Layers 2-5 of Adult Rat and Cat Neocortex: Triple Intracellular Recordings and Biocytin Labelling in Vitro", "journal": "Cereb Cortex. 2002 Sep;12(9):936-53.", "year": "2002", "DOI": "10.1093/cercor/12.9.936", "PMID": "12183393", "pre_layer": "L4", "pre_type": "EXC", "post_layer": "L3", "post_type": "EXC", "only_septum": "no", "cp_empirical": 28, "species": "rat", "area": "SM", "samples": 25}, {"ID": "04b3dd80-0954-4dee-8cce-d32c9d798ac5", "type": "connection_probability_invitro", "authors": "Alex M Thomson, David C West, Yun Wang, A Peter Bannister", "title": "Synaptic Connections and Small Circuits Involving Excitatory and Inhibitory Neurons in Layers 2-5 of Adult Rat and Cat Neocortex: Triple Intracellular Recordings and Biocytin Labelling in Vitro", "journal": "Cereb Cortex. 2002 Sep;12(9):936-53.", "year": "2002", "DOI": "10.1093/cercor/12.9.936", "PMID": "12183393", "pre_layer": "L5", "pre_type": "EXC", "post_layer": "L5", "post_type": "EXC", "only_septum": "no", "cp_empirical": 9, "species": "rat", "area": "SM", "samples": 163}, {"ID": "a8bc6716-4189-49dc-aaf9-081e530fc536", "type": "connection_probability_invitro", "authors": "Alex M Thomson, David C West, Yun Wang, A Peter Bannister", "title": "Synaptic Connections and Small Circuits Involving Excitatory and Inhibitory Neurons in Layers 2-5 of Adult Rat and Cat Neocortex: Triple Intracellular Recordings and Biocytin Labelling in Vitro", "journal": "Cereb Cortex. 2002 Sep;12(9):936-53.", "year": "2002", "DOI": "10.1093/cercor/12.9.936", "PMID": "12183393", "pre_layer": "L5", "pre_type": "EXC", "post_layer": "L3", "post_type": "EXC", "only_septum": "no", "cp_empirical": 3, "species": "rat", "area": "SM", "samples": 29}, {"ID": "dd748df9-12cd-4183-879d-3d4a01648842", "type": "connection_probability_invitro", "authors": "Yumiko Yoshimura, Jami L M Dantzker, Edward M Callaway", "title": "Excitatory Cortical Neurons Form Fine-Scale Functional Networks", "journal": "Nature. 2005 Feb 24;433(7028):868-73.", "year": "2005", "DOI": "10.1038/nature03252", "PMID": "15729343", "pre_layer": "L23", "pre_type": "EXC", "post_layer": "L23", "post_type": "EXC", "only_septum": "no", "cp_empirical": 20, "species": "rat", "area": "VC", "samples": 112}, {"ID": "ab3dd055-4a4b-4e8f-8a32-4793c7016da6", "type": "connection_probability_invitro", "authors": "Yumiko Yoshimura, Jami L M Dantzker, Edward M Callaway", "title": "Excitatory Cortical Neurons Form Fine-Scale Functional Networks", "journal": "Nature. 2005 Feb 24;433(7028):868-73.", "year": "2005", "DOI": "10.1038/nature03252", "PMID": "15729343", "pre_layer": "L4", "pre_type": "EXC", "post_layer": "L23", "post_type": "EXC", "only_septum": "no", "cp_empirical": 20, "species": "rat", "area": "VC", "samples": 50}, {"ID": "2c91035c-ab5f-4d17-87bc-3bd0d50b5655", "type": "connection_probability_invivo", "authors": "Jean-S\u00e9bastien Jouhanneau, Jens Kremkow, James F A Poulet", "title": "Single Synaptic Inputs Drive High-Precision Action Potentials in Parvalbumin Expressing GABA-ergic Cortical Neurons in Vivo", "journal": "Nat Commun. 2018 Apr 18;9(1):1540.", "year": "2018", "DOI": "10.1038/s41467-018-03995-2", "PMID": "29670095", "pre_layer": "L23", "pre_type": "EXC", "post_layer": "L23", "post_type": "EXC", "only_septum": "no", "cp_empirical": 7, "species": "mouse", "area": "barrel", "samples": 774}, {"ID": "751f5584-c779-46ab-a5ef-9622095c0634", "type": "connection_probability_invitro", "authors": "Sonja B Hofer, Ho Ko, Bruno Pichler, Joshua Vogelstein, Hana Ros, Hongkui Zeng, Ed Lein, Nicholas A Lesica, Thomas D Mrsic-Flogel", "title": "Differential Connectivity and Response Dynamics of Excitatory and Inhibitory Neurons in Visual Cortex", "journal": "Nat Neurosci. 2011 Jul 17;14(8):1045-52.", "year": "2011", "DOI": "10.1038/nn.2876", "PMID": "21765421", "pre_layer": "L23", "pre_type": "EXC", "post_layer": "L23", "post_type": "EXC", "only_septum": "no", "cp_empirical": 19, "species": "mouse", "area": "VC", "samples": 235}, {"ID": "f1ba71df-15b6-4fc4-8587-319290fed8d5", "type": "connection_probability_invivo", "authors": "Jean-S\u00e9bastien Jouhanneau, Jens Kremkow, Anja L Dorrn, James F A Poulet", "title": "In Vivo Monosynaptic Excitatory Transmission Between Layer 2 Cortical Pyramidal Neurons", "journal": "Cell Rep. 2015 Dec 15;13(10):2098-106.", "year": "2015", "DOI": "10.1016/j.celrep.2015.11.011", "PMID": "26670044", "pre_layer": "L2", "pre_type": "EXC", "post_layer": "L2", "post_type": "EXC", "only_septum": "no", "cp_empirical": 7, "species": "mouse", "area": "barrel", "samples": 878}]
 
 
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figures/plotting_settings.mplstyle DELETED
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- ytick.labelsize : 15
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-
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- text.usetex: false
 
 
 
 
 
 
 
 
 
 
 
 
 
figures/plotting_utils.py DELETED
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- import matplotlib.pyplot as plt
2
- import numpy as np
3
-
4
-
5
- # short fun to colorize boxplots
6
- def color_boxplot(thos, bp, colors, alpha=0.7):
7
- for key in ["boxes", "medians"]:
8
- for i, b in enumerate(bp[key]):
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- b.set(color=colors[i], alpha=alpha)
10
-
11
- for idx, patch in enumerate(bp["boxes"]):
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-
15
- for key in ["whiskers", "caps"]:
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- for i in range(thos.shape[1]):
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- bp[key][2 * i].set(color=colors[i], alpha=alpha)
18
- bp[key][2 * i + 1].set(color=colors[i], alpha=alpha)
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-
20
-
21
- # plotting 1D marginals, e.g., for showing posterior predictives.
22
- def custom_marginal_plot(
23
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24
- x,
25
- points,
26
- x_label,
27
- points_label,
28
- color,
29
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31
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33
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34
- plot_legend=True,
35
- handlelength=0.8,
36
- bbox_to_anchor=(1, 1),
37
- points_line_style="-",
38
- ):
39
- # Cross validation
40
- assert x.shape[1] == 7
41
- assert isinstance(x, np.ndarray)
42
- assert not show_xlabels or labels
43
- for idx in range(x.shape[1]):
44
-
45
- axi = ax[idx]
46
- plt.sca(axi)
47
- axi.spines["right"].set_visible(False)
48
- axi.spines["top"].set_visible(False)
49
- axi.spines["left"].set_visible(False)
50
- plt.yticks([])
51
- if points is not None:
52
- plt.axvline(
53
- x=points[0, idx], color="k", label=points_label, ls=points_line_style
54
- )
55
-
56
- plt.xlim([0, 1])
57
- plt.xticks([0, 1])
58
- _, bins, _ = plt.hist(
59
- x[:1000, idx],
60
- bins=num_bins,
61
- alpha=alpha,
62
- color=color,
63
- label=x_label,
64
- histtype=histtype,
65
- )
66
- if show_xlabels:
67
- plt.xlabel(labels[idx])
68
- # plt.sca(ax[-1, -1])
69
- # plt.axis("off")
70
- # plt.sca(ax[-1, -2])
71
- if idx == 6 and plot_legend:
72
- plt.legend(handlelength=handlelength, bbox_to_anchor=bbox_to_anchor)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
figures/supplementary_figures/plotting_settings.mplstyle DELETED
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1
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figures/supplementary_figures/supp_fig1_sbi_benchmark.ipynb DELETED
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results/benchmark_poisson_glm_snpe_samples/.hydra/config.yaml DELETED
@@ -1,24 +0,0 @@
1
- compute_metrics: true
2
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3
- seed: null
4
- algorithm:
5
- name: SNPE
6
- run: sbi.snpe.run
7
- device: cpu
8
- params:
9
- num_rounds: 10
10
- neural_net: mdn
11
- hidden_features: 50
12
- simulation_batch_size: 1000
13
- training_batch_size: 1000
14
- num_atoms: 5
15
- automatic_transforms_enabled: false
16
- z_score_x: false
17
- z_score_theta: true
18
- stop_after_epochs: 100
19
- task:
20
- name: poisson_glm
21
- num_simulations: 1000000
22
- num_observation: 5
23
- joblib:
24
- n_jobs: 20
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
results/benchmark_poisson_glm_snpe_samples/.hydra/hydra.yaml DELETED
@@ -1,142 +0,0 @@
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- hydra:
2
- run:
3
- dir: outputs/${now:%Y-%m-%d}/${now:%H-%M-%S}
4
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5
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6
- subdir: ${hydra.job.num}
7
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16
- stream: ext://sys.stdout
17
- root:
18
- level: INFO
19
- handlers:
20
- - console
21
- loggers:
22
- logging_example:
23
- level: DEBUG
24
- disable_existing_loggers: false
25
- job_logging:
26
- version: 1
27
- formatters:
28
- simple:
29
- format: '[%(asctime)s][%(name)s][%(levelname)s] - %(message)s'
30
- handlers:
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- console:
32
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33
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34
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35
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37
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38
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46
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- max_batch_size: null
48
- launcher:
49
- _target_: hydra_plugins.hydra_joblib_launcher.joblib_launcher.JoblibLauncher
50
- n_jobs: -1
51
- backend: null
52
- prefer: processes
53
- require: null
54
- verbose: 0
55
- timeout: null
56
- pre_dispatch: 2*n_jobs
57
- batch_size: auto
58
- temp_folder: null
59
- max_nbytes: null
60
- mmap_mode: r
61
- help:
62
- app_name: ${hydra.job.name}
63
- header: '${hydra.help.app_name} is powered by Hydra.
64
-
65
- '
66
- footer: 'Powered by Hydra (https://hydra.cc)
67
-
68
- Use --hydra-help to view Hydra specific help
69
-
70
- '
71
- template: '${hydra.help.header}
72
-
73
- == Configuration groups ==
74
-
75
- Compose your configuration from those groups (group=option)
76
-
77
-
78
- $APP_CONFIG_GROUPS
79
-
80
-
81
- == Config ==
82
-
83
- Override anything in the config (foo.bar=value)
84
-
85
-
86
- $CONFIG
87
-
88
-
89
- ${hydra.help.footer}
90
-
91
- '
92
- hydra_help:
93
- hydra_help: ???
94
- template: 'Hydra (${hydra.runtime.version})
95
-
96
- See https://hydra.cc for more info.
97
-
98
-
99
- == Flags ==
100
-
101
- $FLAGS_HELP
102
-
103
-
104
- == Configuration groups ==
105
-
106
- Compose your configuration from those groups (For example, append hydra/job_logging=disabled
107
- to command line)
108
-
109
-
110
- $HYDRA_CONFIG_GROUPS
111
-
112
-
113
- Use ''--cfg hydra'' to Show the Hydra config.
114
-
115
- '
116
- output_subdir: .hydra
117
- overrides:
118
- hydra:
119
- - hydra/launcher=joblib
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- task:
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- - task=poisson_glm
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- - task.num_observation=5
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- - task.num_simulations=1000000
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- - algorithm=snpe
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- - +joblib.n_jobs=20
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- job:
127
- name: run
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- override_dirname: +joblib.n_jobs=20,algorithm=snpe,task.num_observation=5,task.num_simulations=1000000,task=poisson_glm
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- id: run_79
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- num: 79
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- config_name: config
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- env_set: {}
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- env_copy: []
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- config:
135
- override_dirname:
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- kv_sep: '='
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- item_sep: ','
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- exclude_keys: []
139
- runtime:
140
- version: 1.0.3
141
- cwd: /home/janfb/qode/benchmarking_sbi
142
- verbose: false
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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- algorithm:
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