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25 Brain Research Through Advancing Innovative Neurotechnologies® Initiative The Brain Research Through Advancing Innovative Neurotechnologies® Initiative, or The BRAIN Initiative®, established with the aim of revolutionizing our understanding of the human brain, was announced by President Obama in 2013. In the y...
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Building on recent discoveries, the BRAIN Initiative aimed to accelerate the development and application of innovative technologies to produce a revolutionary, dynamic picture of the human brain. This dynamic picture would show how individual cells and complex neural circuits interact in both time and space, provid...
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NIMH launched the Emergency Department Screening for Teens at Risk for Suicide study in a network of hospital emergency departments across the United States as a part of the institute’s research agenda for suicide prevention. The study aimed to develop and test a personalized, computer-based suicide risk screening ...
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2014 26 2014 On April 2, the NIMH-funded BrainSpan Atlas of the Developing Human Brain consortium project reported its first major findings. The effort was intended to provide a comprehensive three-dimensional atlas of the brain and profile gene activity across the brain, beginning prenatally. Human adult whole ...
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NIMH published a new Strategic Plan for Research. Informed by the successes and challenges of recent years, the plan updated the strategic objectives outlined in 2008 to balance the need for long-term investments in basic research with urgent mental health needs. The four strategic objectives in the 2015 plan were: ...
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to intervene • Strive for prevention and cures • Strengthen the public health impact of NIMH-supported research 27 The Study to Assess Risk and Resilience in Servicemembers-Longitudinal Study (STARRS-LS) was launched as an extension of Army STARRS, representing a partnership between NIMH and the U.S. Army, U.S. De...
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2015 Researchers in NIMH’s Recovery After an Initial Schizophrenia Episode (RAISE) initiative reported that treating people with first-episode psychosis using a team- based coordinated specialty care approach produced better clinical and functional outcomes than typical community care. Investigators also found that ...
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NIMH engaged extensively with organizations and communities—including federal partners, advocacy groups, professional organizations, and local and state mental health authorities—to ensure RAISE findings would be relevant and actionable for rapid translation into clinical practice. These collaborations, coupled wit...
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Ultimately, RAISE not only contributed to a new way to organize and deliver treatment, but it also produced findings that changed the standard of practice for early schizophrenia treatment in the United States. 28 2015 2017 On February 6, NIMH announced the creation of the Early Psychosis Intervention Network (E...
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NIMH supported the launch of a major BRAIN Initiative effort to discover and catalog the brain’s “parts list.” This effort, known as the BRAIN Initiative Cell Census Network, was established as a cooperative network of comprehensive centers, specialized laboratories, and an integrated data center. “ Before we can ...
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Former NIH Director Francis S. Collins, M.D., Ph.D. Speech on the BRAIN Initiative ” On April 29, results published from the Emergency Department Safety Assessment and Follow-up Evaluation study showed that hospital emergency departments can play a vital role in reducing suicide attempts among adults. The study wa...
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On July 11, NIMH proposed the creation of the NIMH Data Archive to serve as an online resource for investigators seeking to share data, tools, methods, and analyses from research with human participants. The NIMH Data Archive, which was built upon the preexisting National Database for Autism Research, brought togeth...
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29 NIH released the first dataset from the Adolescent Brain Cognitive Development℠ Study, the largest long-term study of brain development and child health ever conducted in the United States, to the scientific community through the NIMH Data Archive. The comprehensive dataset—including measures of brain developmen...
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2018 NIH launched the Helping to End Addiction Long-term® Initiative as an ambitious, high-priority effort across the institutes to speed scientific solutions to stem the opioid public health crisis. Launched in April 2018, the initiative focused on improving prevention and treatment strategies for opioid misuse an...
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Researchers in the NIMH Intramural Research Program collaborated with the Indian Health Service (IHS) to pilot suicide risk screening in IHS emergency departments serving American Indian/Alaska Native communities. A follow-up quality improvement project further demonstrated the feasibility of suicide risk screening ...
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On March 5, the FDA approved esketamine as a fast-acting and noninvasive treatment for depression that works via a different neurochemical pathway from other antidepressants. In the 1990s, Dr. Charney and another researcher, John Krystal, M.D., found that intravenous ketamine improved depressive symptoms within hou...
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2019 30 2019 On March 19, the FDA approved the medication brexanolone as the first successful treatment for severe postpartum depression. In the 1980s and 1990s, NIMH intramural researcher Steven Paul, M.D., showed that the neurosteroid allopregnanolone promoted anesthesia during pregnancy by stimulating the inh...
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NIMH Director Joshua A. Gordon, M.D., Ph.D. NIMH Director’s Message ” NIMH established the Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness research center program to support the advancement of clinical research and practice. The program was designe...
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31 3D illustration of coronavirus. Credit: www.istockphoto.com/portfolio/ BlackJack3D. 2019 Impact of the Coronavirus Pandemic Coronavirus (COVID-19), a disease caused by the SARS- CoV-2 virus, was discovered in December 2019 and quickly spread around the world. The COVID-19 pandemic disproportionately impacte...
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In response, NIMH funded research to understand the long-term mental health impacts of the pandemic and evaluate scalable interventions that could meet the increased mental health needs of diverse populations. NIMH committed to prioritizing research on COVID-19 and funding studies examining the pandemic’s ongoing i...
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2020 32 2020 NIH launched a public-private partnership to meet the urgent need for early therapeutic interventions for people at risk of developing schizophrenia. The Accelerating Medicines Partnership® program for schizophrenia brought together NIH, the FDA, and multiple nonprofit and private organizations in a...
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NIMH Director Joshua A. Gordon, M.D., Ph.D. Announcement on the launch of the Accelerating Medicines Partnership® program for schizophrenia ” 2021 The BRAIN Initiative Cell Census Network unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from...
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NIMH supported the launch of two transformative projects through the BRAIN Initiative: the BRAIN Initiative Cell Atlas Network and the Armamentarium for Precision Brain Cell Access. The BRAIN Initiative Cell Atlas Network represented the next step in NIH’s efforts to generate a complete reference atlas of cell types...
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The White House Report on Mental Health Research Priorities, published in February, outlined administration-wide needs and opportunities to advance mental health research. Areas of emphasis included addressing mental health inequities, understanding and leveraging digital mental health interventions, and supporting...
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NIMH celebrated its 75th anniversary. A yearlong program of events launched with the inaugural scientific symposium, “The Evolution of Mental Health Research.” Over the anniversary year, NIMH sponsored numerous activities, including symposiums, lectures, and sessions at scientific meetings. NIMH also shared stories ...
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spirit of those contributing to the institute’s mission. Looking back on the many NIMH-supported advancements gives reason to celebrate and provides perspective for moving forward. Mental illnesses are common, affecting tens of millions of people in the United States—and worldwide— each year. Suicide remains an urge...
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The evolving NIMH Strategic Plan for Research maps our path. We have charted numerous routes—from basic research to translational efforts to clinical studies testing novel approaches in community settings. We are also ready to adapt to the challenges and opportunities ahead. Over the next 75 years and beyond, NIMH ...
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Shervert H. Frazier Frank J. Sullivan (Acting) Lewis L. Judd Alan I. Leshner (Acting) Frederick K. Goodwin Rex William Cowdry (Acting) Steven E. Hyman Richard K. Nakamura (Acting) Thomas R. Insel Bruce Cuthbert (Acting) Joshua A. Gordon Tenure 1949–1964 1964–1970 1970–1977 1977–1978 1978–1984 1984 198...
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378−381. Scientific Research Axelrod, J. (1986). Doing research in the intramural program of the National Institutes of Health. Perspectives in Biology and Medicine, 29(3), 131−137. Cohen, R. A. (1984). Studies on the etiology of schizophrenia. In DeWitt Stetten, Jr., & W.T. Carrigan (Eds.), NIH: An account of res...
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W. T. Carrigan (Eds.), NIH: An account of research in its laboratories and clinics (pp. 36−47). Academic Press. Pickren, W. E., & Schneider, S. F. (Eds.). (2005). Psychology and the National Institute of Mental Health: A historical analysis of science, practice, and policy. American Psychological Association. Org...
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37 Frazier, S. H. (1998). NIMH during the tenure of director Shervert H. Frazier, M.D. (1984-1986): The mental disorder-based reorganization and research on schizophrenia and severe mental disorders. American Journal of Psychiatry, 155(9), 20−24. Goodwin, F. K. (1998). NIMH during the tenure of director Frederick K...
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Judd, L. L. (1998). Historical highlights of the National Institute of Mental Health from 1946 to the present. American Journal of Psychiatry, 155(9), 3−8. Judd, L. L. (1998). NIMH during the tenure of director Lewis L. Judd, M.D. (1987-1990): The decade of the brain and the four national research plans. American J...
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Segal, J. (Ed.). (1975). Research in the service of mental health: Report of the research task force of the National Institute of Mental Health. National Institute of Mental Health. Shaping National Mental Health Policy Foley, H. A. (1975). Community mental health legislation: The formative process. Lexington Books....
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Grob, G. N., & Goldman, H. H. (2006). The dilemma of federal mental health policy: Radical reform or incremental change? Rutgers University Press. Insel, T. (2022). Healing: Our path from mental illness to mental health. Penguin Press. Kolb, L. C., Frazier, S. H., & Sirovatka, P. (2000). The National Institute of Me...
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• Adolescent Brain Cognitive Development℠ Study • Brain Research Through Advancing Innovative Neurotechnologies® and The BRAIN Initiative® • ACCELERATING MEDICINES PARTNERSHIP® • Helping to End Addiction Long-term® This publication was made possible by the NIMH 75th Anniversary Steering Committee and Workin...
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40 Contact the National Institute of Mental Health 6001 Executive Boulevard MSC 9663 Bethesda, MD 20892-9663 Email: nimhinfo@nih.gov www.nimh.nih.gov Follow us on social media: www.nimh.nih.gov/socialmedia NIH Publication No. 23-MH-8213 [Table Data] [Table: table_2_1] | About NIMH The National Institute of M...
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[Table: table_39_1] | Col0 | 36 | | --- | --- | [Table: table_39_2] | Name | Tenure | | --- | --- | | Robert H. Felix | 1949–1964 | | Stanley F. Yolles | 1964–1970 | | Bertram S. Brown | 1970–1977 | | Francis N. Waldrop (Acting) | 1977–1978 | | Herbert Pardes | 1978–1984 | | Larry Silver (Acting) | 1984 | | Shervert...
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[Table: table_42_1] | Col0 | The following are registered service marks and trademarks of the U.S. Department of Health and Human Services (HHS): • Adolescent Brain Cognitive Development℠ Study • Brain Research Through Advancing Innovative Neurotechnologies® and The BRAIN Initiative® • ACCELERATING MEDICINES PARTNERSHI...
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the National Institute of Mental Health as the source. You may not reuse or copy the images. Read our copyright policy to learn more about our guidelines for reusing NIMH content at www.nimh.nih.gov/copyright. 40 | | --- | --- |
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Tips for Talking With a Health Care Provider About Your Mental Health Don’t wait for a health care provider to ask about your mental health. Start the conversation. Here are five tips to help prepare and guide you on talking to a health care provider about your mental health and getting the most out of your v...
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Mental health is an integral part of health, and people with mental disorders can often be at risk for other medical conditions, such as heart disease or diabetes. In many primary care settings, you may be asked if you’re feeling anxious or depressed, or if you have had thoughts of suicide. Even if your PCP doesn’t ...
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you might have. This worksheet may help you prepare your questions or concerns. ● Prepare a list of your medications. It’s important to tell your health care provider about all the medications you’re taking, including over-the-counter (nonprescription) drugs, herbal remedies, vitamins, and supplements. This worksheet...
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It can be difficult to absorb all the information your health care provider shares, especially if you are not feeling well. Sometimes it’s helpful to bring a close friend or relative to your appointment. A companion can be there for support, help you take notes, and remember what you and the provider discussed. They...
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4. Be honest. Your health care provider can help you get better only if you have open and honest communication. It is important to remember that discussions between you and a health care provider are private and cannot be shared with anyone without your expressed permission. Describe all your symptoms to your provi...
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Symptoms of mental illnesses may include: ● Persistent sad, anxious, or “empty” mood ● Feelings of hopelessness or pessimism ● Irritability ● Feelings of guilt, worthlessness, or helplessness ● Loss of interest or pleasure in hobbies and activities ● Decreased energy or fatigue ● Moving or talking more slowly ● ...
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physical cause and/or that do not ease even with treatment 5. Ask questions. If you have questions or concerns, ask the health care provider for more information about the mental health diagnosis or treatment. If a provider suggests a treatment option that you’re not comfortable or familiar with, express your conce...
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Schizophrenia National Institute of Mental Health What is schizophrenia? Schizophrenia is a serious mental illness that affects how a person thinks, feels, and behaves. People with schizophrenia may appear to have lost touch with reality, which can be distressing for them and their family and friends. The symptom...
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What are the signs and symptoms of schizophrenia? It’s important to recognize the symptoms of schizophrenia and seek help as early as possible. People with schizophrenia are usually diagnosed between the ages of 16 and 30, after the first episode of psychosis. Starting treatment as soon as possible following the fi...
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Schizophrenia symptoms can differ from person to person, but they generally fall into three main categories: psychotic, negative, and cognitive. Psychotic symptoms Psychotic symptoms include changes in the way a person thinks, acts, and experiences the world. A person experiencing psychotic symptoms often has disr...
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► Delusions are when a person has strong beliefs that are not objectively true and may seem irrational to others. For example, individuals experiencing delusions may believe that people on the radio and television are sending special messages that require a certain response, or they may believe that they are in da...
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► Having trouble planning and sticking with routine activities, such as grocery shopping ► Having trouble anticipating and being motivated by pleasure in everyday life ► Talking in a dull voice and showing limited facial expression ► Avoiding social interaction or interacting in socially awkward ways ► Hav...
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These negative symptoms are sometimes mistaken for symptoms of depression or other mental illnesses. Cognitive symptoms Cognitive symptoms include problems with attention, concentration, and memory. These symptoms can make it hard to follow a conversation, learn new things, or remember appointments. A person’s lev...
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► Having trouble processing information to make decisions ► Having trouble using information immediately after learning it ► Having trouble focusing or paying attention Risk of violence Most people with schizophrenia are not violent. Overall, people with schizophrenia are more likely than those without the illne...
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What causes schizophrenia? Several factors may contribute to a person’s risk of developing schizophrenia. Genes Schizophrenia sometimes runs in families. However, just because one family member has schizophrenia, it does not mean that other members of the family also will have it. Studies suggest that many differe...
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Brain structure and function Research shows that people with schizophrenia may be more likely to have subtle differences in the size of certain brain areas and in connections between brain areas. Some of these brain differences may develop before birth. Researchers are working to better understand how brain struct...
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If a person’s symptoms do not improve with usual antipsychotic medication, they may be prescribed clozapine. People who take clozapine must have regular blood tests to check for a potentially dangerous side effect that occurs in 1% to 2% of patients. People respond to antipsychotic medication in different ways. It ...
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Read the most up-to-date information on medications, side effects, and warnings on the U.S. Food and Drug Administration (FDA) website at www.fda.gov/drugsatfda. Psychosocial treatments Psychosocial treatments help people find solutions to everyday challenges and manage symptoms while attending school, working, an...
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Learn more about psychosocial treatments and therapies at www.nimh.nih.gov/psychotherapies. Family education and support Educational programs can help family and friends learn about symptoms of schizophrenia, treatment options, and strategies for helping loved ones with the illness. These programs can help frien...
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Compared with typical care, CSC is more effective in reducing symptoms, improving quality of life, and increasing involvement in work or school. Assertive community treatment Assertive community treatment is designed to help individuals with schizophrenia who are likely to experience multiple hospitalizations or h...
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If you have concerns about your mental health, talk to a primary care provider. They can refer you to a qualified mental health professional, such as a psychologist, psychiatrist, or clinical social worker, who can help you figure out the next steps. Find tips for talking with a health care provider about your ment...
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How can I help a friend or relative with schizophrenia? It can be difficult to know how to help someone who is experiencing psychosis. Here are some things you can do: ► Help them get treatment and encourage them to stay in treatment. ► Remember that their beliefs or hallucinations seem very real to them. ► Be...
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► Look for support groups and family education programs, such as those offered by the National Alliance on Mental Illness at www.nami.org/Support-Education. Clinical trials Clinical trials are research studies that look at ways to prevent, detect, or treat diseases and conditions. These studies help show whethe...
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For more information Learn more by visiting NIMH’s website at www.nimh.nih.gov/health. For information on a wide variety of health topics, visit the National Library of Medicine’s MedlinePlus resource at https://medlineplus.gov. Contact us National Institute of Mental Health Office of Science Policy, Planning, a...
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National Institute of Mental Health U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 24-MH-8082 Revised 2024
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5 Action Steps to Help Someone Having Thoughts of Suicide We can all take steps to help prevent suicide. Knowing the warning signs for suicide and how to get help can save lives. Here are 5 steps you can take to #BeThe1To help someone who is having thoughts of suicide: 1. ASK: “Are you thinking about suicide?” I...
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4. HELP THEM CONNECT: Connecting the person with the 988 Suicide & Crisis Lifeline (call or text 988) and other community resources can give them a safety net when they need it. You can also help them reach out to a trusted family member, friend, spiritual advisor, or mental health professional. 5. FOLLOW UP: Stay...
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FREQUENTLY ASKED QUESTIONS About Suicide Suicide is a leading cause of death in the United States and a major public health concern. When a person dies by suicide, the effects are felt by family, friends, and communities. This brochure can help you, a friend, or a family member learn more about the warning sign...
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A suicide attempt is when people harm themselves with the goal of ending their life, but they do not die. Avoid using terms such as “committing suicide,” “successful suicide,” or “failed suicide” when referring to suicide and suicide attempts, as these terms often carry negative meanings. Who is at risk for suicid...
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● Having recently been released from prison or jail ● Exposure, either directly or indirectly, to others’ suicidal behavior, such as that of family members, peers, or celebrities Most people who have risk factors for suicide will not attempt suicide, and it is difficult to tell who will act on suicidal thoughts. Al...
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Warning signs that someone may be at immediate risk for attempting suicide include: ● Talking about wanting to die or wanting to kill themselves ● Talking about feeling empty or hopeless or having no reason to live ● Talking about feeling trapped or feeling that there are no solutions ● Feeling unbearable emo...
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● Displaying extreme mood swings, suddenly changing from very sad to very calm or happy ● Making a plan or looking for ways to kill themselves, such as searching for lethal methods online, stockpiling pills, or buying a gun ● Talking about feeling great guilt or shame ● Using alcohol or drugs more often ● A...
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can help people learn new ways of dealing with stressful experiences. CBT helps people learn to recognize their thought patterns and consider alternative actions when thoughts of suicide arise. ● Dialectical Behavior Therapy (DBT): DBT is a type of psychotherapy that has been shown to reduce suicidal behavior in a...
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● Brief Intervention Strategies: Research has shown that creating a safety plan or crisis response plan—with specific instructions for what to do and how to get help when having thoughts about suicide—can help reduce a person’s risk of acting on suicidal thoughts. Staying connected and following up with people who ...
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● Collaborative Care: Collaborative care is a team-based approach to mental health care. A behavioral health care manager will work with the person, their primary health care provider, and mental health specialists to develop a treatment plan. Collaborative care has been shown to be an effective way to treat depres...
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Call 911 if there is an immediate life-threatening situation. You also can contact: 988 Suicide & Crisis Lifeline 988lifeline.org Call or text 988; Llame al 988 (para ayuda en español) The Lifeline provides 24-hour, confidential support to anyone in suicidal crisis or emotional distress. Call or text 988 to conn...
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If you see messages or live streaming content that suggests someone is actively engaging in suicidal behavior, you can contact safety teams at the social media company. They will reach out to connect the person with the help they need. Does asking someone about suicide put the idea in their head? No. Studies have...
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How do suicide rates differ among groups of people? Data show that the rates of suicide attempts and suicide deaths vary according to characteristics such as age, sex, race, ethnicity, and geographic location. The most recent statistics and information on suicide risk are available on the Centers for Disease Cont...
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To find mental health treatment facilities in your area, call the Substance Abuse and Mental Health Services Administration’s National Helpline at 1-800-662-4357, visit their website at https://findtreatment.gov, or text your ZIP code to 435748. Where can I learn about NIMH research on suicide? NIMH supports promis...
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To learn more about NIMH research priorities and recent research on suicide prevention, visit the NIMH website at www.nimh.nih.gov. For additional information about suicide prevention efforts, visit the National Action Alliance for Suicide Prevention at https://theactionalliance.org and Zero Suicide at http://zero...
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Talk to your health care provider about clinical trials, their benefits and risks, and whether one is right for you. For more information, visit www.nimh.nih.gov/clinicaltrials. Reprints This publication is in the public domain and may be reproduced or copied without permission from NIMH. We encourage you to rep...
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ClinicalTrials.gov www.clinicaltrials.gov https://salud.nih.gov/investigacion-clinica (en español) National Institute of Mental Health Office of Science Policy, Planning, and Communications 6001 Executive Boulevard Room 6200, MSC 9663 Bethesda, MD 20892-9663 Toll-free: 1-866-615-6464 Email: nimhinfo@ni...
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WARNING SIGNS OF SUICIDE: The behaviors listed below may be some of the signs that someone is thinking about suicide. TALKING ABOUT: Wanting to die Great guilt or shame Being a burden to others FEELING: Empty, hopeless, trapped, or having no reason to live Extremely sad, more anxious, agitated, or full ...
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988 Suicide & Crisis Lifeline Call or text 988 Chat at 988lifeline.org National Institute of Mental Health www.nimh.nih.gov/suicideprevention NIMH Identifier No. OM 25-4316
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Psychiatric-Mental Health Nursing SENIOR CONTRIBUTING AUTHORS REBECCA PUCHKORS, BAYLOR UNIVERSITY JEANNE SAUNDERS, DAYTONA STATE COLLEGE DAVID SHARP, MISSISSIPPI COLLEGE OpenStax Rice University 6100 Main Street MS-375 Houston, Texas 77005 To learn more about OpenStax, visit https://openstax.org. Individual...
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- - - - If you redistribute this textbook in a digital format (including but not limited to PDF and HTML), then you must retain on every page the following attribution: “Access for free at openstax.org.” If you redistribute this textbook in a print format, then you must include on every physical page the f...
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For questions regarding this licensing, please contact support@openstax.org. Trademarks The OpenStax name, OpenStax logo, OpenStax book covers, OpenStax CNX name, OpenStax CNX logo, OpenStax Tutor name, Openstax Tutor logo, Connexions name, Connexions logo, Rice University name, and Rice University logo are not su...
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978-1-711472-91-1 978-1-711472-90-4 978-1-961584-42-6 2024 OPENSTAX OpenStax provides free, peer-reviewed, openly licensed textbooks for introductory college and Advanced Placement® courses and low-cost, personalized courseware that helps students learn. A nonprofit ed tech initiative ba...
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PHILANTHROPIC SUPPORT OpenStax is grateful for the generous philanthropic partners who advance our mission to improve educational access and learning for everyone. To see the impact of our supporter community and our most updated list of partners, please visit openstax.org/foundation. Arnold Ventures Chan Zuc...
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Stand Together The William and Flora Hewlett Foundation Robin and Sandy Stuart Foundation The Hewlett-Packard Company The Stuart Family Foundation Intel Inc. Rusty and John Jaggers Tammy and Guillermo Treviño Valhalla Charitable Foundation The Calvin K. Kazanjian Economics Foundation White Star Educ...
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CHAPTER 1 CHAPTER 2 CHAPTER 3 CHAPTER 4 CHAPTER 5 CHAPTER 6 CHAPTER 7 CHAPTER 8 CHAPTER 9 CHAPTER 10 CHAPTER 11 CHAPTER 12 CHAPTER 13 CHAPTER 14 CHAPTER 15 CHAPTER 16 CHAPTER 17 CHAPTER 18 CHAPTER 19 CHAPTER 20 CHAPTER 21 CHAPTER 22 CHAPTER 23 CHAPTER 24 CHAPTER 25 CHAPTER 26 CHAPTER 27 CHAPT...
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