text:
@article{savchuk_ontogenesis_2019,
	title = {Ontogenesis of human fetal testicular steroidogenesis at early gestational age},
	volume = {141},
	issn = {0039128X},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0039128X1830223X},
	doi = {10.1016/j.steroids.2018.12.001},
	abstract = {The onset of steroidogenesis in human fetal testes ({HFT}) during the ﬁrst trimester is poorly investigated. One important unresolved question is the ontogeny of steroidogenic enzymes and formation of steroidogenic pathways in the {HFT} at early pregnancy.},
	pages = {96--103},
	journaltitle = {Steroids},
	author = {Savchuk, I. and Morvan, M.L. and Antignac, J.P. and Kurek, M. and Le Bizec, B. and Söder, O. and Svechnikov, K.},
	urldate = {2019-03-29},
	date = {2019-01},
	langid = {english},
	file = {Savchuk et al. - 2019 - Ontogenesis of human fetal testicular steroidogene.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\9FHL9HY8\\Savchuk et al. - 2019 - Ontogenesis of human fetal testicular steroidogene.pdf:application/pdf}
}

@article{hernandez-mesa_potential_2019,
	title = {Potential of ion mobility-mass spectrometry for both targeted and non-targeted analysis of phase {II} steroid metabolites in urine},
	volume = {1},
	issn = {25901346},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S2590134619300027},
	doi = {10.1016/j.acax.2019.100006},
	abstract = {In recent years, the commercialization of hybrid ion mobility-mass spectrometers and their integration in traditional {LC}-{MS} workﬂows provide new opportunities to extend the current boundaries of targeted and non-targeted analyses. When coupled to {LC}-{MS}, ion mobility spectrometry ({IMS}) provides a novel characterization parameter, the so-called averaged collision cross section ({CCS}, U), as well as improves method selectivity and sensitivity by the separation of isobaric and isomeric molecules and the isolation of the analytes of interest from background noise. In this work, we have explored the potential and advantages of this technology for carrying out the determination of phase {II} steroid metabolites (i.e. androgen and estrogen conjugates, including glucuronide and sulfate compounds; n ¼ 25) in urine samples. These molecules have been selected based on their relevance in the ﬁelds of chemical food safety and doping control, as well as in metabolomics studies. The inﬂuence of urine matrix on the {CCS} of steroid metabolites was evaluated in order to give more conﬁdence to current {CCS} databases and support its use as complementary information to retention time (Rt) and mass spectra for compound identiﬁcation. Samples were only diluted 10-fold with aqueous formic acid (0.1\%, v/v) prior analysis. Only an almost insigniﬁcant effect of adult bovine urine matrix on the {CCS} of certain steroid metabolites was observed in comparison with calve urine matrix, which is a less complex sample. In addition, high accuracy was achieved for {CCS} measurements carried out over four months ({DCCS} {\textless} 1.3\% for 99.8\% of {CCS} measurements; n ¼ 1806). Interestingly, it has been observed that signal-to-noise (S/N) ratio could be improved at least 2 or 7-fold when {IMS} is combined with {LC}-{MS}. In addition to the separation of isomeric steroid pairs (i.e. etiocholanolone glucuronide and epiandrosterone glucuronide, as well as 19noretiocholanolone glucuronide and 19-norandrosterone glucuronide), steroid-based ions were also separated in the {IMS} dimension from co-eluting matrix compounds that presented similar mass-tocharge ratio (m/z). Finally, based on {CCS} measurements and as a proof of concept, 17a-boldenone glucuronide has been identiﬁed as one of the main metabolites resulted from boldione administration to calves.},
	pages = {100006},
	journaltitle = {Analytica Chimica Acta: X},
	author = {Hernández-Mesa, Maykel and Monteau, Fabrice and Le Bizec, Bruno and Dervilly-Pinel, Gaud},
	urldate = {2019-03-29},
	date = {2019-03},
	langid = {english},
	file = {Hernández-Mesa et al. - 2019 - Potential of ion mobility-mass spectrometry for bo.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\TLSRX3KE\\Hernández-Mesa et al. - 2019 - Potential of ion mobility-mass spectrometry for bo.pdf:application/pdf}
}

@article{bichon_determination_2018,
	title = {Determination of l -cysteine origin on the basis of its δ 15 N values},
	volume = {260},
	issn = {03088146},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0308814618305818},
	doi = {10.1016/j.foodchem.2018.03.139},
	abstract = {The majority of L-cysteine is obtained industrially by hydrolysis of animal materials, such as poultry feathers. Despite widespread belief, there is little evidence that human hair is used as a source material and its use is explicitly banned in the European Union (2000/63/{EC} decision). We developed an isotope ratio mass spectrometric ({EA}-{IRMS}) method to determine carbon and nitrogen isotopic ratio in cysteine preparations and related compounds, e.g. cystine and carbocysteine. A threshold relying on the 15N/14N was established to diﬀerentiate between hair and feathers; a value below 6.6‰ indicates a poultry feathers origin. Global uncertainty of measurement was found to be 0.1‰ for δ15N (sample size of 0.5–1.8 mg).},
	pages = {283--288},
	journaltitle = {Food Chemistry},
	author = {Bichon, Emmanuelle and Sitthisack, Parina and Sérée-Vattier, Ludivine and Prévost, Stéphanie and Schiphorst, Anne-Marie and Pouponneau, Karinne and Monteau, Fabrice and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2018-09},
	langid = {english},
	file = {Bichon et al. - 2018 - Determination of l -cysteine origin on the basis o.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VVJEHL49\\Bichon et al. - 2018 - Determination of l -cysteine origin on the basis o.pdf:application/pdf}
}

@article{herpin_comparison_2018,
	title = {Comparison between liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry for beta-agonists screening in feeding stuff},
	volume = {1086},
	issn = {15700232},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S1570023218300928},
	doi = {10.1016/j.jchromb.2018.04.023},
	pages = {130--137},
	journaltitle = {Journal of Chromatography B},
	author = {Herpin, L. and Bichon, E. and Rambaud, L. and Monteau, F. and Le Bizec, B.},
	urldate = {2019-03-29},
	date = {2018-06},
	langid = {english},
	file = {Herpin et al. - 2018 - Comparison between liquid chromatography and super.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\SP3LHVUS\\Herpin et al. - 2018 - Comparison between liquid chromatography and super.pdf:application/pdf}
}

@article{doue_supercritical_2018,
	title = {Supercritical fluid chromatography applied to the highly selective isolation of urinary steroid hormones prior to {GC}/{MS} analysis},
	volume = {1086},
	issn = {15700232},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S1570023218300643},
	doi = {10.1016/j.jchromb.2018.04.024},
	abstract = {To assess the presence of prohibited anabolic substances used to promote growth in livestock, calf urine is the most relevant matrix. However, the sample preparation methods (required to remove unwanted matrix components and fractionate isobaric species that may be unresolved by gas chromatography- mass spectrometry {GC}/ {MS}) are long and complex. In this context, semi-preparative supercritical ﬂuid chromatography ({SFC}) was considered to possibly simplify the sample preparation in reducing the number of procedures.},
	pages = {97--104},
	journaltitle = {Journal of Chromatography B},
	author = {Doué, Mickael and West, Caroline and Bichon, Emmanuelle and Le Bizec, Bruno and Lesellier, Eric},
	urldate = {2019-03-29},
	date = {2018-06},
	langid = {english},
	file = {Doué et al. - 2018 - Supercritical fluid chromatography applied to the .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\SYIMXI58\\Doué et al. - 2018 - Supercritical fluid chromatography applied to the .pdf:application/pdf}
}

@article{bichon_simultaneous_2018,
	title = {Simultaneous analysis of historical, emerging and novel brominated flame retardants in food and feed using a common extraction and purification method},
	volume = {205},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0045653518307185},
	doi = {10.1016/j.chemosphere.2018.04.070},
	abstract = {Brominated Flame Retardants ({BFRs}) are still widely used for industrial purposes. These contaminants may enter the food chain where they mainly occur in food of animal origin. The aim of our work was to provide a unique method able to quantify the widest range of {BFRs} in feed and food items. After freezedrying and grinding, a pressurized liquid extraction was carried out. The extract was puriﬁed on acidiﬁed silica, Florisil® and carbon columns, the four separated fractions were analyzed by gas and liquid chromatography coupled to high resolution and tandem mass spectrometry. Isotopic dilution was preferentially used when commercial labelled compounds were available. Analytical sensitivity was in accordance with the expectations of Recommendation 2014/118/{EU} for {PBDEs}, {HBCDDs}, {TBBPA}, {TBBPAbME}, {EHTBB}, {BEHTEBP} and {TBBPA}-{bME}. Additional {BFRs} were included in this analytical method with the same level of performances ({LOQs} below 0.01 ng {gÀ}1 ww). These are {PBBs}, {pTBX}, {TBCT}, {PBBz}, {PBT}, {PBEB}, {HBBz}, {BTBPE}, {OBIND} and T23BPIC. However, some of the {BFRs} listed in Recommendation 2014/118/ {EU} are not yet covered by our analytical method, i.e. {TBBPA}-{bOHEE}, {TBBPA}-{bAE}, {TBBPA}-{bGE}, {TBBPAbDiBPrE}, {TBBPS}, {TBBPS}-{bME}, {TDBPP}, {EBTEBPI}, {HBCYD} and {DBNPG}. The uncertainty measurement was fully calculated for 21 of the 31 analytes monitored in the method. Reproducibility uncertainty was below 23\% in isotopic dilution. Certiﬁed reference materials are now required to better characterize the trueness of this method, which was applied in the French National Control Plans.},
	pages = {31--40},
	journaltitle = {Chemosphere},
	author = {Bichon, Emmanuelle and Guiffard, Ingrid and Vénisseau, Anaïs and Lesquin, Elodie and Vaccher, Vincent and Marchand, Philippe and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2018-08},
	langid = {english},
	file = {Bichon et al. - 2018 - Simultaneous analysis of historical, emerging and .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\SBZ3WJE5\\Bichon et al. - 2018 - Simultaneous analysis of historical, emerging and .pdf:application/pdf}
}

@article{hort_ochratoxin_2018,
	title = {Ochratoxin A determination in swine muscle and liver from French conventional or organic farming production systems},
	volume = {1092},
	issn = {15700232},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S1570023218301223},
	doi = {10.1016/j.jchromb.2018.05.040},
	abstract = {Consumers generally considered organic products to be healthier and safer but data regarding the contamination of organic products are scarce. This study evaluated the impact of the farming system on the levels of ochratoxin A ({OTA}) in the tissues of French pigs (muscle and liver) reared following three different types of production (organic, Label Rouge and conventional). Because {OTA} is present at trace levels in animal products, a sensitive ultrahigh performance liquid chromatography–tandem mass spectrometry method using stable isotope dilution assay was developed and validated. {OTA} was detected or quantified ({LOQ} of 0.10 µg kg-1) in 67\% (n = 47) of the 70 pig liver samples analysed, with concentrations ranging from {\textless} 0.10 to 3.65 µg kg-1. The maximum concentration was found in a sample from organic production but there were no significant differences in the content of {OTA} between farming systems. {OTA} was above the {LOQ} in four out of 25 samples of the pork muscles. A good agreement was found between {OTA} levels in muscle and liver (liver concentration = 2.9 x {OTA} muscle concentration, r = 0.981).},
	pages = {131--137},
	journaltitle = {Journal of Chromatography B},
	author = {Hort, Vincent and Nicolas, Marina and Minvielle, Brice and Maleix, Corentin and Desbourdes, Caroline and Hommet, Frédéric and Dragacci, Sylviane and Dervilly-Pinel, Gaud and Engel, Erwan and Guérin, Thierry},
	urldate = {2019-03-29},
	date = {2018-08},
	langid = {english},
	file = {Hort et al. - 2018 - Ochratoxin A determination in swine muscle and liv.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\3ZXUHNLK\\Hort et al. - 2018 - Ochratoxin A determination in swine muscle and liv.pdf:application/pdf}
}

@article{abdel_malak_occurrence_2018,
	title = {Occurrence of Dechlorane Plus and related compounds in catfish ( Silurus spp.) from rivers in France},
	volume = {207},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0045653518309500},
	doi = {10.1016/j.chemosphere.2018.05.101},
	abstract = {Dechlorane related compounds ({DRCs}), including Dechlorane Plus (syn-{DP} and anti-{DP}), Dechlorane-601, -602, -603 and Chlordene Plus ({CP}), constitute a group of polychlorinated ﬂame retardants ({FRs}) that are still of industrial use. In particular, {DRCs} have been detected in various environmental matrices and in different aquatic and terrestrial biota, thus exhibiting bioaccumulation and biomagniﬁcation potentials. The present study aimed at producing ﬁrst occurrence data of a range of {DRCs} in Silurus spp. samples from different rivers located in France. Determination was carried out by gas chromatography highresolution mass spectrometry after a sample clean-up based on a multilayer silica column and gel permeation chromatography. The concentration of monitored {SDRCs} ranged from 1.58 to 408 pg {gÀ}1 wet weight (54e11100 pg {gÀ}1 lipid weight). The fractional abundance of syn- and anti-{DP} stereoisomers was similar to that reported by other studies with an average equal to 0.60. Dec-601 was not detected in any sample. Detection frequencies ranged between 34 and 100\% for other {DRCs}. Investigated correlations between {DRCs} and polychlorobiphenyls ({PCBs}) suggest a link with lipid content but independent contamination sources.},
	pages = {413--420},
	journaltitle = {Chemosphere},
	author = {Abdel Malak, Inas and Cariou, Ronan and Vénisseau, Anaïs and Dervilly-Pinel, Gaud and Jaber, Farouk and Babut, Marc and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2018-09},
	langid = {english},
	file = {Abdel Malak et al. - 2018 - Occurrence of Dechlorane Plus and related compound.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\4CVF4RKE\\Abdel Malak et al. - 2018 - Occurrence of Dechlorane Plus and related compound.pdf:application/pdf}
}

@article{bertrand_successes_2017,
	title = {Successes and pitfalls in automated dereplication strategy using liquid chromatography coupled to mass spectrometry data: A {CASMI} 2016 experience},
	volume = {21},
	issn = {18743900},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S1874390016303974},
	doi = {10.1016/j.phytol.2016.12.025},
	shorttitle = {Successes and pitfalls in automated dereplication strategy using liquid chromatography coupled to mass spectrometry data},
	abstract = {Automated annotation of data, originating from liquid chromatography coupled to high-resolution mass spectrometry proﬁles ({LC}–{HRMS}), remains a highly challenging task. Therefore, the Critical Assessment of Small Molecule Identiﬁcation ({CASMI}) Contest (http://casmi-contest.org/) represents a unique opportunity to blindly evaluate annotation workﬂows. The 2016 {CASMI} contest consisted of 16 {LC}–{HRMS}/ {MS} proﬁles with 18 detected peaks to annotate. Those peaks corresponded to compounds from natural origin. An R script based on the {XCMS}, {IPO}, {RMassBank}, {CAMERA} and {MeHaloCoA} packages was devised. Two other external tools: {SIRIUS}3 and {CFM}-{ID} were also integrated for molecular formulae and in silico fragmentation calculation, respectively. This script was used to perform peak picking, spectral interpretation, molecular formula determination and database search for structural determination. Finally, the structures were further discriminated based on in silico fragmentation. After the release of the {CASMI} contest solutions, successes and failures of the proposed script were investigated. In most cases, no differences were observed in the rank of the correct structure when using raw {LC}–{HRMS} data or manually obtained {MS} and {MS}/{MS} spectra. However, the study of the few cases where differences were detected tends to show that automatic detection of {MS}2 data within the raw {LC}–{MS} data yielded more accurate identiﬁcation. The failures in proposing the correct structure within the submission list were related to the absence of the right structure in the interrogated databases. However, very close structure were proposed in ﬁrst rank indicating that such approaches are able to rapidly determine the carbon skeleton of the structure; the medium rank of the correct structure in the proposed list for each peak of interest being 2nd.},
	pages = {297--305},
	journaltitle = {Phytochemistry Letters},
	author = {Bertrand, Samuel and Guitton, Yann and Roullier, Catherine},
	urldate = {2019-03-29},
	date = {2017-09},
	langid = {english},
	file = {Bertrand et al. - 2017 - Successes and pitfalls in automated dereplication .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\TNKYDRDU\\Bertrand et al. - 2017 - Successes and pitfalls in automated dereplication .pdf:application/pdf}
}

@article{goyet_haustorium_2017,
	title = {Haustorium initiation in the obligate parasitic plant Phelipanche ramosa involves a host-exudated cytokinin signal},
	volume = {68},
	issn = {0022-0957, 1460-2431},
	url = {https://academic.oup.com/jxb/article/68/20/5539/4560671},
	doi = {10.1093/jxb/erx359},
	abstract = {The heterotrophic lifestyle of parasitic plants relies on the development of the haustorium, a specific infectious organ required for attachment to host roots. While haustorium development is initiated upon chemodetection of host-derived molecules in hemiparasitic plants, the induction of haustorium formation remains largely unknown in holoparasitic species such as Phelipanche ramosa. This work demonstrates that the root exudates of the host plant Brassica napus contain allelochemicals displaying haustorium-inducing activity on P. ramosa germinating seeds, which increases the parasite aggressiveness. A de novo assembled transcriptome and microarray approach with P. ramosa during early haustorium formation upon treatment with B. napus root exudates allowed the identification of differentially expressed genes involved in hormone signaling. Bioassays using exogenous cytokinins and the specific cytokinin receptor inhibitor {PI}-55 showed that cytokinins induced haustorium formation and increased parasite aggressiveness. Root exudates triggered the expression of cytokinin-responsive genes during early haustorium development in germinated seeds, and bio-guided {UPLC}-{ESI}(+)-/{MS}/{MS} analysis showed that these exudates contain a cytokinin with dihydrozeatin characteristics. These results suggest that cytokinins constitutively exudated from host roots play a major role in haustorium formation and aggressiveness in P. ramosa.},
	pages = {5539--5552},
	number = {20},
	journaltitle = {Journal of Experimental Botany},
	author = {Goyet, Vincent and Billard, Estelle and Pouvreau, Jean-Bernard and Lechat, Marc-Marie and Pelletier, Sandra and Bahut, Muriel and Monteau, Fabrice and Spíchal, Lukáš and Delavault, Philippe and Montiel, Grégory and Simier, Philippe},
	urldate = {2019-03-29},
	date = {2017-11-28},
	langid = {english},
	file = {Goyet et al. - 2017 - Haustorium initiation in the obligate parasitic pl.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VJSMMX62\\Goyet et al. - 2017 - Haustorium initiation in the obligate parasitic pl.pdf:application/pdf}
}

@article{ratel_liver_2017,
	title = {Liver volatolomics to reveal poultry exposure to γ-hexabromocyclododecane ({HBCD})},
	volume = {189},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S004565351731487X},
	doi = {10.1016/j.chemosphere.2017.09.074},
	abstract = {Hexabromocyclododecane ({HBCD}) is a critical emerging brominated ﬂame retardant to which consumers can be exposed at high doses through a single food intake. Based on an animal experiment involving 3 groups of laying hens fed during 70 days with a control diet or g-{HBCD}-contaminated diets at 0.1 or 10 mg g-{HBCD} {gÀ}1 feed, this study aims to use the volatolome of biological samples for revealing markers of livestock exposure to {HBCD}. Liquid chromatographyetandem mass spectrometry was used to monitor the time-course of {HBCD} levels in bodily samples. Each liver was analyzed by solid-phase microextractionegas chromatographyemass spectrometry for volatolome proﬁling. After 70 days, g-{HBCD} concentrations in egg yolk, fat, liver and serum reached 54 ± 4, 85 ± 6, 31 ± 6, and 32 ± 4 ng {gÀ}1 lw, respectively, for the low exposure level and 4.6þ/5.7, 7.8þ/6.5, 3.9þ/3.0 and 3.9þ/6.1 mg {gÀ}1 lw, respectively, for the high exposure level. Isomerization of g-{HBCD} into a- and b-{HBCD} was observed in all tissues, at least for the high exposure level. Volatolome data allowed a signiﬁcant discrimination between control and exposed animals whatever the feed contamination load, demonstrating a liver metabolic response to g-{HBCD} exposure. The relevance of the twenty nine volatile exposure markers tentatively identiﬁed was discussed in light of literature data.},
	pages = {634--642},
	journaltitle = {Chemosphere},
	author = {Ratel, Jérémy and Planche, Christelle and Mercier, Frédéric and Blinet, Patrick and Kondjoyan, Nathalie and Marchand, Philippe and Fournier, Agnès and Travel, Angélique and Jondreville, Catherine and Engel, Erwan},
	urldate = {2019-03-29},
	date = {2017-12},
	langid = {english},
	file = {Ratel et al. - 2017 - Liver volatolomics to reveal poultry exposure to γ.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VKMGW3X6\\Ratel et al. - 2017 - Liver volatolomics to reveal poultry exposure to γ.pdf:application/pdf}
}

@article{gouilleux_high-throughput_2018,
	title = {High-throughput authentication of edible oils with benchtop Ultrafast 2D {NMR}},
	volume = {244},
	issn = {03088146},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S030881461731645X},
	doi = {10.1016/j.foodchem.2017.10.016},
	abstract = {We report the use of an Ultrafast 2D {NMR} approach applied on a benchtop {NMR} system (43 {MHz}) for the authentication of edible oils. Our results demonstrate that a proﬁling strategy based on fast 2D {NMR} spectra recorded in 2.4 min is more eﬃcient than the standard 1D experiments to classify oils from diﬀerent botanical origins, since 1D spectra on the same samples suﬀer from strong peak overlaps. Six edible oils with diﬀerent botanical origins (olive, hazelnut, sesame, rapeseed, corn and sunﬂower) have been clearly discriminated by {PCA} analysis. Furthermore, we show how this approach combined with a {PLS} model can detect adulteration processes such as the addition of hazelnut oil into olive oil, a common fraud in food industry.},
	pages = {153--158},
	journaltitle = {Food Chemistry},
	author = {Gouilleux, B. and Marchand, J. and Charrier, B. and Remaud, G.S. and Giraudeau, P.},
	urldate = {2019-03-29},
	date = {2018-04},
	langid = {english},
	file = {Gouilleux et al. - 2018 - High-throughput authentication of edible oils with.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\D89CVDQ8\\Gouilleux et al. - 2018 - High-throughput authentication of edible oils with.pdf:application/pdf}
}

@article{guillaume_effect_2018,
	title = {Effect of a Photostimulating Treatment, in Winter, on Steroids Profile and Sexual Behavior of Light Stallions},
	volume = {66},
	issn = {07370806},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0737080618302417},
	doi = {10.1016/j.jevs.2018.05.037},
	pages = {66--67},
	journaltitle = {Journal of Equine Veterinary Science},
	author = {Guillaume, D. and Grosboillot, L. and Chesneau, D. and De Geoffroy, F. and Prevost, S. and Keller, M. and Dervilly-Pinel, G.},
	urldate = {2019-03-29},
	date = {2018-07},
	langid = {english},
	file = {Guillaume et al. - 2018 - Effect of a Photostimulating Treatment, in Winter,.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VWWD8HYU\\Guillaume et al. - 2018 - Effect of a Photostimulating Treatment, in Winter,.pdf:application/pdf}
}

@article{liber_past_2019,
	title = {Past and recent state of sediment contamination by persistent organic pollutants ({POPs}) in the Rhône River: Overview of ecotoxicological implications},
	volume = {646},
	issn = {00489697},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0048969718328353},
	doi = {10.1016/j.scitotenv.2018.07.340},
	shorttitle = {Past and recent state of sediment contamination by persistent organic pollutants ({POPs}) in the Rhône River},
	abstract = {Twenty-one sediment samples were taken from ﬁve dated sediment cores collected along the Rhône River from 2008 to 2011. A total of 17 polychlorinated dibenzo-p-dioxins and dibenzofurans ({PCDD}/Fs), 7 polychlorinated biphenyls ({PCBs}), 8 polybrominated diphenyl ethers ({PBDEs}), 3 polybrominated biphenyls ({PBBs}), 3 hexabromocyclododecanes ({HBCD}) and 31 organochlorine pesticides ({OCPs}) were investigated to provide information on deposition dynamics in time and space, but also regarding the ecotoxicological risks associated with these contaminants. Median concentrations of total {PBDEs} are nine times lower than the levels of total {PCBs} along the entire studied stretch of the Rhône River. The results show that total {PBDEs} concentrations range from 0.06 to 239 μg·kg−1 {DW} with a median value of 3.81 μg·kg−1 {DW} and a maximum concentration measured in the years 2000s. These maximum concentrations are identical to those measured for total {PCBs} at the end of the 1990s, but show a different pattern of distribution. Abnormal dichlorodiphenyltrichloroethane ({DDT}) levels were also detected in the downstream section of the river, with a peak concentration of 147.5 μg·kg−1 {DW} measured at the {GEC} site from 2005 onwards. Analyses of the enantiomeric fractions reveal a fresh input resulting from a technical formulation. Sediments from the core sampled at the most downstream site ({GEC}) are found to be highly toxic to organisms living nearby, particularly because of the total {PCDD}/Fs, {DDE} and {DDT} levels. In addition, based on available sediment quality guidelines, there may be a potential bioaccumulation risk for humans not only for these three compounds of concern but also for total {PCBs} and 7 out of the 8 analysed {PBDEs}. © 2018 Elsevier B.V. All rights reserved.},
	pages = {1037--1046},
	journaltitle = {Science of The Total Environment},
	author = {Liber, Yohan and Mourier, Brice and Marchand, Philippe and Bichon, Emmanuelle and Perrodin, Yves and Bedell, Jean-Philippe},
	urldate = {2019-03-29},
	date = {2019-01},
	langid = {english},
	file = {Liber et al. - 2019 - Past and recent state of sediment contamination by.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\NLAFLNVY\\Liber et al. - 2019 - Past and recent state of sediment contamination by.pdf:application/pdf}
}

@article{tejada-casado_collision_2018,
	title = {Collision cross section ({CCS}) as a complementary parameter to characterize human and veterinary drugs},
	volume = {1043},
	issn = {00032670},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0003267018311693},
	doi = {10.1016/j.aca.2018.09.065},
	pages = {52--63},
	journaltitle = {Analytica Chimica Acta},
	author = {Tejada-Casado, Carmen and Hernández-Mesa, Maykel and Monteau, Fabrice and Lara, Francisco J. and Olmo-Iruela, Monsalud del and García-Campaña, Ana M. and Le Bizec, Bruno and Dervilly-Pinel, Gaud},
	urldate = {2019-03-29},
	date = {2018-12},
	langid = {english},
	file = {Tejada-Casado et al. - 2018 - Collision cross section (CCS) as a complementary p.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\XSPQIKPC\\Tejada-Casado et al. - 2018 - Collision cross section (CCS) as a complementary p.pdf:application/pdf}
}

@article{cano-sancho_challenging_2018,
	title = {The challenging use and interpretation of circulating biomarkers of exposure to persistent organic pollutants in environmental health: Comparison of lipid adjustment approaches in a case study related to endometriosis},
	volume = {200},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0045653518303321},
	doi = {10.1016/j.chemosphere.2018.02.120},
	shorttitle = {The challenging use and interpretation of circulating biomarkers of exposure to persistent organic pollutants in environmental health},
	abstract = {The gold-standard matrix for measuring the internal levels of persistent organic pollutants ({POPs}) is the adipose tissue, however in epidemiological studies the use of serum is preferred due to the low cost and higher accessibility. The interpretation of serum biomarkers is tightly related to the understanding of the underlying causal structure relating the {POPs}, serum lipids and the disease. Considering the extended beneﬁts of using serum biomarkers we aimed to further examine if through statistical modelling we would be able to improve the use and interpretation of serum biomarkers in the study of endometriosis. Hence, we have conducted a systematic comparison of statistical approaches commonly used to lipidadjust the circulating biomarkers of {POPs} based on existing methods, using data from a pilot casecontrol study focused on severe deep inﬁltrating endometriosis. The odds ratios ({ORs}) obtained from unconditional regression for those models with serum biomarkers were further compared to those obtained from adipose tissue. The results of this exploratory study did not support the use of blood biomarkers as proxy estimates of {POPs} in adipose tissue to implement in risk models for endometriosis with the available statistical approaches to correct for lipids. The current statistical approaches commonly used to lipid-adjust circulating {POPs}, do not fully represent the underlying biological complexity between {POPs}, lipids and disease (especially those directly or indirectly affecting or affected by lipid metabolism). Hence, further investigations are warranted to improve the use and interpretation of blood biomarkers under complex scenarios of lipid dynamics.},
	pages = {388--396},
	journaltitle = {Chemosphere},
	author = {Cano-Sancho, German and Labrune, Léa and Ploteau, Stéphane and Marchand, Philippe and Le Bizec, Bruno and Antignac, Jean-Philippe},
	urldate = {2019-03-29},
	date = {2018-06},
	langid = {english},
	file = {Cano-Sancho et al. - 2018 - The challenging use and interpretation of circulat.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\GYWUV9E5\\Cano-Sancho et al. - 2018 - The challenging use and interpretation of circulat.pdf:application/pdf}
}

@article{dervilly-pinel_when_2018,
	title = {When {LC}-{HRMS} metabolomics gets {ISO}17025 accredited and ready for official controls – application to the screening of forbidden compounds in livestock},
	volume = {35},
	issn = {1944-0049, 1944-0057},
	url = {https://www.tandfonline.com/doi/full/10.1080/19440049.2018.1496280},
	doi = {10.1080/19440049.2018.1496280},
	abstract = {Within the particular context of controlling chemical residues in food, an alternative to targeted approaches has emerged; it consists in the characterisation of physiological perturbations induced upon exposure of animals to a given chemical substance/class of substances to highlight suitable biomarkers addressing safety and/or regulatory issues. Metabolomics in particular has been investigated in the hope of identifying such biomarkers, and a range of studies have demonstrated the efficiency of the strategy. Until very recently, steps remained to be taken towards official or commercial implementation of corresponding tools. In particular, the lack of guidelines and criteria to validate such methods that do not target specific chemical species per se, constituted a bottleneck. In the present work, a metabolomics model dedicated to the detection of β-agonist administration in bovines has been developed and fully validated; criteria (selectivity, robustness, stability, suspicion threshold definition, false positive and false negative rates) have been proposed in agreement with {EU} expectations (Dec 2002/657), enabling demonstration that performances comply with screening requirements.},
	pages = {1948--1958},
	number = {10},
	journaltitle = {Food Additives \& Contaminants: Part A},
	author = {Dervilly-Pinel, Gaud and Royer, Anne-Lise and Bozzetta, Elena and Pezzolato, Marzia and Herpin, Loïc and Prevost, Stéphanie and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2018-10-03},
	langid = {english},
	file = {Dervilly-Pinel et al. - 2018 - When LC-HRMS metabolomics gets ISO17025 accredited.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\3A974K9X\\Dervilly-Pinel et al. - 2018 - When LC-HRMS metabolomics gets ISO17025 accredited.pdf:application/pdf}
}

@article{boue_development_2018,
	title = {Development of a Cryptosporidium-arsenic multi-risk assessment model for infant formula prepared with tap water in France},
	volume = {108},
	issn = {09639969},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0963996918302382},
	doi = {10.1016/j.foodres.2018.03.054},
	abstract = {Tap water is used in France to reconstitute powder infant formula, although it is not sterile and possibly contaminated by microbiological and chemical hazards. The present study aims to quantify risks of using tap water in France for the preparation of infant formula, during the ﬁrst six months of life.},
	pages = {558--570},
	journaltitle = {Food Research International},
	author = {Boué, G. and Wasiewska, L.A. and Cummins, E. and Antignac, J.-P. and Le Bizec, B. and Guillou, S. and Membré, J.-M.},
	urldate = {2019-03-29},
	date = {2018-06},
	langid = {english},
	file = {Boué et al. - 2018 - Development of a Cryptosporidium-arsenic multi-ris.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\Y9ZC88A2\\Boué et al. - 2018 - Development of a Cryptosporidium-arsenic multi-ris.pdf:application/pdf}
}

@article{le_boucher_spatial_2016,
	title = {Spatial Distribution of Lactococcus lactis Colonies Modulates the Production of Major Metabolites during the Ripening of a Model Cheese},
	volume = {82},
	issn = {0099-2240, 1098-5336},
	url = {http://aem.asm.org/lookup/doi/10.1128/AEM.02621-15},
	doi = {10.1128/AEM.02621-15},
	pages = {202--210},
	number = {1},
	journaltitle = {Applied and Environmental Microbiology},
	author = {Le Boucher, Clémentine and Gagnaire, Valérie and Briard-Bion, Valérie and Jardin, Julien and Maillard, Marie-Bernadette and Dervilly-Pinel, Gaud and Le Bizec, Bruno and Lortal, Sylvie and Jeanson, Sophie and Thierry, Anne},
	editor = {Elkins, C. A.},
	urldate = {2019-03-29},
	date = {2016-01-01},
	langid = {english},
	file = {Le Boucher et al. - 2016 - Spatial Distribution of Lactococcus lactis Colonie.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\TEZ5E56M\\Le Boucher et al. - 2016 - Spatial Distribution of Lactococcus lactis Colonie.pdf:application/pdf}
}

@article{maurice_short-term_2015,
	title = {Short-term effects of a perinatal exposure to the {HBCDD} α-isomer in rats: Assessment of early motor and sensory development, spontaneous locomotor activity and anxiety in pups},
	volume = {52},
	issn = {08920362},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0892036215300234},
	doi = {10.1016/j.ntt.2015.08.005},
	shorttitle = {Short-term effects of a perinatal exposure to the {HBCDD} α-isomer in rats},
	abstract = {The present study investigated the developmental neurotoxicity of an early exposure to α-{HBCDD} through the ingestion of contaminated hen's egg in pregnant and lactating Wistar female rats. Hens were given α-{HBCDDcontaminated} feed (40 ng/g fresh matter) for 5 and 10 days, which produced eggs with {HBCDD} content of 33 and 102 ng/g lipid weight, respectively. Female rats were administered daily p.o. with an appropriate volume of the whole egg from the day of fertilization ({GD}0) to the weaning day for pups ({PND}21). Fetuses and pups were thus exposed continuously to α-{HBCDD} via the dam over a whole 42-day period that included both gestation and lactation. The administered egg volume was calculated on the basis of daily egg consumption in humans (0.7 egg/person/day) and duration of gestation and lactation in both species, which led animals to be exposed to α-{HBCDD} at levels of 22 and 66 ng/kg/day, respectively. Neurobehavioral development of pups was investigated from {PND}3 to {PND}25 using various tasks including the righting reﬂex ({PND}4), the grasping reﬂex ({PND}5), the negative geotaxis ({PND}9), the forelimb grip strength test ({PND}10) and the locomotor coordination test ({PND}20). Pup ultrasonic vocalizations were also recorded daily from {PND}4 to {PND}14. After weaning, behaviors related to spontaneous locomotor activity and anxiety were examined in the open-ﬁeld ({PND}25) and in an elevated-plus maze ({PND}26), respectively. The results showed a signiﬁcant decrease in body weight of pups exposed to the lower {HBCDD} level from {PND}3 to {PND}28, whereas the weight of rat pups given 66 ng/kg/day of {HBCDD} was not different from controls. During the ﬁrst 3 weeks of life, impairments in motor maturation of pups were observed in a dose-dependent manner depending on the test, whereas no signiﬁcant differences were reported between male and female pups. At {PND}26, the anxiety level of female rats exposed to the lowest dose of {HBCDD} (22 ng/kg/day) was signiﬁcantly reduced whereas it remained unchanged in males. No signiﬁcant variations were measured in rats exposed to the higher level of {HBCDD} (66 ng/kg/day). These results suggest the potent developmental neurotoxicity of an early chronic exposure to the {HBCDD} α-isomer through the ingestion of hen's eggs contaminated with this pollutant and question the long-lasting consequences of this exposure on behavior abilities and brain functioning in adulthood.},
	pages = {170--180},
	journaltitle = {Neurotoxicology and Teratology},
	author = {Maurice, Nicolas and Olry, Jean-Charles and Cariou, Ronan and Dervilly-Pinel, Gaud and Le Bizec, Bruno and Travel, Angélique and Jondreville, Catherine and Schroeder, Henri},
	urldate = {2019-03-29},
	date = {2015-11},
	langid = {english},
	file = {Maurice et al. - 2015 - Short-term effects of a perinatal exposure to the .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\2MTQMKUL\\Maurice et al. - 2015 - Short-term effects of a perinatal exposure to the .pdf:application/pdf}
}

@article{cariou_perfluoroalkyl_2015,
	title = {Perfluoroalkyl acid ({PFAA}) levels and profiles in breast milk, maternal and cord serum of French women and their newborns},
	volume = {84},
	issn = {01604120},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0160412015300209},
	doi = {10.1016/j.envint.2015.07.014},
	abstract = {One major concern regarding perﬂuoroalkyl acids ({PFAAs}) is their potential role in onset of health troubles consecutive to early exposure during the perinatal period. In the present work, the internal exposure levels of 18 targeted {PFAAs} were determined in ca. 100 mother–newborn pairs recruited in France between 2010 and 2013. In serum, the cumulated concentrations of the 7 most frequently detected compounds were 5.70 ng/{mL} and 2.83 ng/{mL} (median values) in maternal and cord serum, respectively. Perﬂuorooctanesulfonic acid ({PFOS}), perﬂuorooctanoic acid ({PFOA}), perﬂuorohexylesulfonic acid ({PFHxS}) and perﬂuorononanoic acid ({PFNA}) contributed to around 90\% of the total {PFAAs} contamination, with concentration levels and contamination proﬁles in accordance with other published work in Europe. Levels measured in breast milk were far lower (20 to 150 fold) than those determined in serum. Associations between the different monitored substances as well as between levels determined in the different investigated biological matrices mostly do not appear statistically signiﬁcant. The estimated materno-foetal transfer would be thus substance-dependant, mainly driven by the physico-chemical properties of the different {PFAAs} (nature of polar group and length of alkylated side chain). We conclude that trans-placental passage and breastfeeding are both signiﬁcant routes of human exposure to {PFAAs}.},
	pages = {71--81},
	journaltitle = {Environment International},
	author = {Cariou, Ronan and Veyrand, Bruno and Yamada, Ami and Berrebi, Alain and Zalko, Daniel and Durand, Sophie and Pollono, Charles and Marchand, Philippe and Leblanc, Jean-Charles and Antignac, Jean-Philippe and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2015-11},
	langid = {english},
	file = {Cariou et al. - 2015 - Perfluoroalkyl acid (PFAA) levels and profiles in .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\MIR6KN6X\\Cariou et al. - 2015 - Perfluoroalkyl acid (PFAA) levels and profiles in .pdf:application/pdf}
}

@article{janssens_simultaneous_2015,
	title = {Simultaneous Detection of Androgen and Estrogen Abuse in Breeding Animals by Gas Chromatography–Mass Spectrometry/Combustion/Isotope Ratio Mass Spectrometry ({GC}-{MS}/C/{IRMS}) Evaluated against Alternative Methods},
	volume = {63},
	issn = {0021-8561, 1520-5118},
	url = {http://pubs.acs.org/doi/10.1021/acs.jafc.5b02746},
	doi = {10.1021/acs.jafc.5b02746},
	abstract = {The administration of synthetic homologues of naturally occurring steroids can be demonstrated by measuring 13C/12C isotopic ratios of their urinary metabolites. Gas chromatography−mass spectrometry/combustion/isotope ratio mass spectrometry ({GC}-{MS}/C/{IRMS}) was used in this study to appraise in a global approach isotopic deviations of two 17βtestosterone metabolites (17α-testosterone and etiocholanolone) and one 17β-estradiol metabolite (17α-estradiol) together with those of 5-androstene-3β,17α-diol as endogenous reference compound ({ERC}). Intermediate precisions of 0.35‰, 1.05‰, 0.35‰, and 0.21‰, respectively, were observed (n = 8). To assess the performance of the analytical method, a bull and a heifer were treated with 17β-testosterone propionate and 17β-estradiol-3-benzoate. The sensitivity of the method permitted the demonstration of 17β-estradiol treatment up to 24 days. For 17β-testosterone treatment, the detection windows were 3 days and 24 days for the bull and the heifer, respectively. The capability of {GC}-{MS}/C/{IRMS} to demonstrate natural steroid abuse for urinary steroids was eventually compared to those of mass spectrometry ({LC}-{MS}/{MS}) when measuring intact steroid esters in blood and hair.},
	pages = {7574--7581},
	number = {34},
	journaltitle = {Journal of Agricultural and Food Chemistry},
	author = {Janssens, Geert and Mangelinckx, Sven and Courtheyn, Dirk and De Kimpe, Norbert and Matthijs, Bert and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2015-09-02},
	langid = {english},
	file = {Janssens et al. - 2015 - Simultaneous Detection of Androgen and Estrogen Ab.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\B82XNF86\\Janssens et al. - 2015 - Simultaneous Detection of Androgen and Estrogen Ab.pdf:application/pdf}
}

@article{couderc_thyroid_2016,
	title = {Thyroid endocrine status of wild European eels ( Anguilla anguilla ) in the Loire (France). Relationships with organic contaminant body burdens},
	volume = {550},
	issn = {00489697},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0048969715312912},
	doi = {10.1016/j.scitotenv.2015.12.136},
	pages = {391--405},
	journaltitle = {Science of The Total Environment},
	author = {Couderc, M. and Marchand, J. and Zalouk-Vergnoux, A. and Kamari, A. and Moreau, B. and Blanchet-Letrouvé, I. and Le Bizec, B. and Mouneyrac, C. and Poirier, L.},
	urldate = {2019-03-29},
	date = {2016-04},
	langid = {english},
	file = {Couderc et al. - 2016 - Thyroid endocrine status of wild European eels ( A.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\YQY5P573\\Couderc et al. - 2016 - Thyroid endocrine status of wild European eels ( A.pdf:application/pdf}
}

@article{beucher_specific_2017,
	title = {Specific characterization of non-steroidal selective androgen peceptor modulators using supercritical fluid chromatography coupled to ion-mobility mass spectrometry: application to the detection of enobosarm in bovine urine: Hyphenation of {SFC} and {IM}-{MS} for growth promoters' detection},
	volume = {9},
	issn = {19427603},
	url = {http://doi.wiley.com/10.1002/dta.1951},
	doi = {10.1002/dta.1951},
	shorttitle = {Specific characterization of non-steroidal selective androgen peceptor modulators using supercritical fluid chromatography coupled to ion-mobility mass spectrometry},
	pages = {179--187},
	number = {2},
	journaltitle = {Drug Testing and Analysis},
	author = {Beucher, Laure and Dervilly-Pinel, Gaud and Cesbron, Nora and Penot, Mylène and Gicquiau, Audrey and Monteau, Fabrice and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2017-02},
	langid = {english},
	file = {Beucher et al. - 2017 - Specific characterization of non-steroidal selecti.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\82ZVWYJS\\Beucher et al. - 2017 - Specific characterization of non-steroidal selecti.pdf:application/pdf}
}

@article{saraoui_inhibition_2016,
	title = {Inhibition mechanism of Listeria monocytogenes by a bioprotective bacteria Lactococcus piscium {CNCM} I-4031},
	volume = {53},
	issn = {07400020},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0740002015000039},
	doi = {10.1016/j.fm.2015.01.002},
	abstract = {Listeria monocytogenes is a pathogenic Gram positive bacterium and the etiologic agent of listeriosis, a severe food-borne disease. Lactococcus piscium {CNCM} I-4031 has the capacity to prevent the growth of L. monocytogenes in contaminated peeled and cooked shrimp. To investigate the inhibititory mechanism, a chemically deﬁned medium ({MSMA}) based on shrimp composition and reproducing the inhibition observed in shrimp was developed. In co-culture at 26 C, L. monocytogenes was reduced by 3e4 log {CFU} {gÀ}1 after 24 h. We have demonstrated that the inhibition was not due to secretion of extracellular antimicrobial compounds as bacteriocins, organic acids and hydrogen peroxide. Global metabolomic ﬁngerprints of these strains in pure culture were assessed by liquid chromatography coupled with high resolution mass spectrometry. Consumption of glucose, amino-acids, vitamins, nitrogen bases, iron and magnesium was measured and competition for some molecules could be hypothesized. However, after 24 h of co-culture, when inhibition of L. monocytogenes occurred, supplementation of the medium with these compounds did not restore its growth. The inhibition was observed in co-culture but not in diffusion chamber when species were separated by a ﬁlter membrane. Taken together, these data indicate that the inhibition mechanism of L. monocytogenes by L. piscium is cell-to-cell contactdependent.},
	pages = {70--78},
	journaltitle = {Food Microbiology},
	author = {Saraoui, Taous and Fall, Papa Abdoulaye and Leroi, Françoise and Antignac, Jean-Philippe and Chéreau, Sylvain and Pilet, Marie France},
	urldate = {2019-03-29},
	date = {2016-02},
	langid = {english},
	file = {Saraoui et al. - 2016 - Inhibition mechanism of Listeria monocytogenes by .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\NPTDXJBW\\Saraoui et al. - 2016 - Inhibition mechanism of Listeria monocytogenes by .pdf:application/pdf}
}

@article{janssens_use_2016,
	title = {The use of gas chromatography–mass spectrometry/combustion/isotope ratio mass spectrometry to demonstrate progesterone treatment in bovines},
	volume = {1449},
	issn = {00219673},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0021967316305295},
	doi = {10.1016/j.chroma.2016.04.074},
	abstract = {Currently, no analytical method is available to demonstrate progesterone administration in biological samples collected in rearing animals, and therefore, tracking the abuse of this popular growth promoter is arduous. In this study, a method is presented to reveal progesterone ({PG}) treatment on the basis of carbon isotope measurement of 5␤-pregnane-3␣, 20␣-diol ({BAA}-{PD}), a major {PG} metabolite excreted in bovine urine, by gas chromatography–mass spectrometry/combustion/isotope ratio mass spectrometry ({GC}–{MS}/C/{IRMS}). 5-Androstene-3␤,17␣-diol ({AEdiol}) is used as endogenous reference compound. Intermediate precisions (n = 11) of 0.56‰ and 0.68‰ have been determined for {AEdiol} and {BAA}-{PD}, respectively. The analytical method was used for the very ﬁrst time to successfully differentiate urine samples collected in treated and untreated animals.},
	pages = {129--140},
	journaltitle = {Journal of Chromatography A},
	author = {Janssens, Geert and Mangelinckx, Sven and Courtheyn, Dirk and De Kimpe, Norbert and Matthijs, Bert and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2016-06},
	langid = {english},
	file = {Janssens et al. - 2016 - The use of gas chromatography–mass spectrometryco.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\ILXZLXE7\\Janssens et al. - 2016 - The use of gas chromatography–mass spectrometryco.pdf:application/pdf}
}

@article{fowler_human_2016,
	title = {Human anogenital distance: an update on fetal smoke-exposure and integration of the perinatal literature on sex differences},
	volume = {31},
	issn = {0268-1161, 1460-2350},
	url = {https://academic.oup.com/humrep/article-lookup/doi/10.1093/humrep/dev323},
	doi = {10.1093/humrep/dev323},
	shorttitle = {Human anogenital distance},
	pages = {463--472},
	number = {2},
	journaltitle = {Human Reproduction},
	author = {Fowler, Paul A. and Filis, Panagiotis and Bhattacharya, Siladitya and le Bizec, Bruno and Antignac, Jean-Philippe and Morvan, Marie-Line and Drake, Amanda J. and Soffientini, Ugo and O'Shaughnessy, Peter J.},
	urldate = {2019-03-29},
	date = {2016-02},
	langid = {english},
	file = {Fowler et al. - 2016 - Human anogenital distance an update on fetal smok.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\B6VSI2YS\\Fowler et al. - 2016 - Human anogenital distance an update on fetal smok.pdf:application/pdf}
}

@article{alves_blue_2016,
	title = {Blue sharks (Prionace glauca) as bioindicators of pollution and health in the Atlantic Ocean: Contamination levels and biochemical stress responses},
	volume = {563-564},
	issn = {00489697},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0048969716307653},
	doi = {10.1016/j.scitotenv.2016.04.085},
	shorttitle = {Blue sharks (Prionace glauca) as bioindicators of pollution and health in the Atlantic Ocean},
	pages = {282--292},
	journaltitle = {Science of The Total Environment},
	author = {Alves, Luís M.F. and Nunes, Margarida and Marchand, Philippe and Le Bizec, Bruno and Mendes, Susana and Correia, João P.S. and Lemos, Marco F.L. and Novais, Sara C.},
	urldate = {2019-03-29},
	date = {2016-09},
	langid = {english},
	file = {Alves et al. - 2016 - Blue sharks (Prionace glauca) as bioindicators of .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\HXNVCHAH\\Alves et al. - 2016 - Blue sharks (Prionace glauca) as bioindicators of .pdf:application/pdf}
}

@article{ben_maamar_ibuprofen_2017,
	title = {Ibuprofen results in alterations of human fetal testis development},
	volume = {7},
	issn = {2045-2322},
	url = {http://www.nature.com/articles/srep44184},
	doi = {10.1038/srep44184},
	number = {1},
	journaltitle = {Scientific Reports},
	author = {Ben Maamar, Millissia and Lesné, Laurianne and Hennig, Kristin and Desdoits-Lethimonier, Christèle and Kilcoyne, Karen R. and Coiffec, Isabelle and Rolland, Antoine D. and Chevrier, Cécile and Kristensen, David M. and Lavoué, Vincent and Antignac, Jean-Philippe and Le Bizec, Bruno and Dejucq-Rainsford, Nathalie and Mitchell, Rod T. and Mazaud-Guittot, Séverine and Jégou, Bernard},
	urldate = {2019-03-29},
	date = {2017-12},
	langid = {english},
	file = {Ben Maamar et al. - 2017 - Ibuprofen results in alterations of human fetal te.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\S5V9DMFS\\Ben Maamar et al. - 2017 - Ibuprofen results in alterations of human fetal te.pdf:application/pdf}
}

@article{dominguez-romero_tissue_2016,
	title = {Tissue Distribution and Transfer to Eggs of Ingested α-Hexabromocyclododecane (α-{HBCDD}) in Laying Hens ( \textit{Gallus domesticus} )},
	volume = {64},
	issn = {0021-8561, 1520-5118},
	url = {http://pubs.acs.org/doi/10.1021/acs.jafc.5b05574},
	doi = {10.1021/acs.jafc.5b05574},
	abstract = {The aim of the current study was to describe the fate of ingested α-hexabromocyclododecane (α-{HBCDD}) in laying hens. Individuals were exposed to two dietary concentrations of α-{HBCDD} (50 and 5 ng g−1 feed) for 18 or 11 weeks followed by a 7-week decontamination period. The results show that no isomerization of α- to β- or γ-{HBCDD} forms occurred, whereas {OH}-{HBCDD} was identiﬁed as a product of α-{HBCDD} metabolism. Irrespective of the level of feed contamination, estimates of steady-state accumulation ratios were 5.2, 3.6, and 9.2 and half-lives were estimated at 17.4, 22.8, and 35.3 days in egg yolk, liver tissue, and abdominal fat, respectively. The steady-state carry-over rate to eggs was 22.9\%. Thus, α-{HBCDD} ingested by laying hens is readily transferred to eggs and signiﬁcantly accumulates in adipose tissue.},
	pages = {2112--2119},
	number = {10},
	journaltitle = {Journal of Agricultural and Food Chemistry},
	author = {Dominguez-Romero, Elena and Cariou, Ronan and Omer, Elsa and Marchand, Philippe and Dervilly-Pinel, Gaud and Le Bizec, Bruno and Travel, Angélique and Jondreville, Catherine},
	urldate = {2019-03-29},
	date = {2016-03-16},
	langid = {english},
	file = {Dominguez-Romero et al. - 2016 - Tissue Distribution and Transfer to Eggs of Ingest.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\BCD96IBL\\Dominguez-Romero et al. - 2016 - Tissue Distribution and Transfer to Eggs of Ingest.pdf:application/pdf}
}

@article{dervilly-pinel_micropollutants_2017,
	title = {Micropollutants and chemical residues in organic and conventional meat},
	volume = {232},
	issn = {03088146},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0308814617305770},
	doi = {10.1016/j.foodchem.2017.04.013},
	abstract = {The chemical contamination levels of both conventional and organic meats were assessed. The objective was to provide occurrence data in a context of chronic exposure. Environmental contaminants (17 polychlorinated dibenzodioxins/dibenzofurans, 18 polychlorinated biphenyls ({PCBs}), 3 hexabromocyclododecane ({HBCD}) isomers, 6 mycotoxins, 6 inorganic compounds) together with chemical residues arising from production inputs (75 antimicrobials, 10 coccidiostats and 121 pesticides) have been selected as relevant compounds. A dedicated sampling strategy, representative of the French production allowed quantiﬁcation of a large sample set (n = 266) including both conventional (n = 139) and organic (n = 127) raw meat from three animal species (bovine, porcine, poultry). While contamination levels below regulatory limits were measured in all the samples, signiﬁcant differences were observed between both species and types of farming. Several environmental contaminants (Dioxins, {PCBs}, {HBCD}, Zn, Cu, Cd, Pb, As) were measured at signiﬁcantly higher levels in organic samples.},
	pages = {218--228},
	journaltitle = {Food Chemistry},
	author = {Dervilly-Pinel, Gaud and Guérin, Thierry and Minvielle, Brice and Travel, Angélique and Normand, Jérôme and Bourin, Marie and Royer, Eric and Dubreil, Estelle and Mompelat, Sophie and Hommet, Frédéric and Nicolas, Marina and Hort, Vincent and Inthavong, Chanthadary and Saint-Hilaire, Mailie and Chafey, Claude and Parinet, Julien and Cariou, Ronan and Marchand, Philippe and Le Bizec, Bruno and Verdon, Eric and Engel, Erwan},
	urldate = {2019-03-29},
	date = {2017-10},
	langid = {english},
	file = {Dervilly-Pinel et al. - 2017 - Micropollutants and chemical residues in organic a.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\7ZJYXKG2\\Dervilly-Pinel et al. - 2017 - Micropollutants and chemical residues in organic a.pdf:application/pdf}
}

@article{cariou_screening_2016,
	title = {Screening halogenated environmental contaminants in biota based on isotopic pattern and mass defect provided by high resolution mass spectrometry profiling},
	volume = {936},
	issn = {00032670},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0003267016308169},
	doi = {10.1016/j.aca.2016.06.053},
	abstract = {In the present work, we addressed the question of global seeking/screening organohalogenated compounds in a large panel of complex biological matrices, with a particular focus on unknown chemicals that may be considered as potential emerging hazards. A ﬁshing strategy was developed based on untargeted proﬁling among full scan acquisition datasets provided by high resolution mass spectrometry. Since large datasets arise from such proﬁling, ﬁltering useful information stands as a central question. In this way, we took advantage of the exact mass differences between Cl and Br isotopes. Indeed, our workﬂow involved an innovative Visual Basic for Applications script aiming at pairing features according to this mass difference, in order to point out potential organohalogenated clusters, preceded by an automated peak picking step based on the {centWave} function (xcms package of open access R programming environment). Then, H/Cl-scale mass defect plots were used to visualize the datasets before and after ﬁltering. The ﬁltering script was successfully applied to a dataset generated upon liquid chromatography coupled to {ESI}(À)-{HRMS} measurement from one eel muscle extract, allowing for realistic manual investigations of ﬁltered clusters. Starting from 9789 initial obtained features, 1994 features were paired in 589 clusters. Hexabromocyclododecane, chlorinated parafﬁn series and various other compounds have been identiﬁed or tentatively identiﬁed, allowing thus broad screening of organohalogenated compounds in this extract. Although realistic, manual review of paired clusters remains time consuming and much effort should be devoted to automation.},
	pages = {130--138},
	journaltitle = {Analytica Chimica Acta},
	author = {Cariou, Ronan and Omer, Elsa and Léon, Alexis and Dervilly-Pinel, Gaud and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2016-09},
	langid = {english},
	file = {Cariou et al. - 2016 - Screening halogenated environmental contaminants i.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\XTBMK3BX\\Cariou et al. - 2016 - Screening halogenated environmental contaminants i.pdf:application/pdf}
}

@article{laparre_impact_2017,
	title = {Impact of storage conditions on the urinary metabolomics fingerprint},
	volume = {951},
	issn = {00032670},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0003267016314052},
	doi = {10.1016/j.aca.2016.11.055},
	abstract = {Urine stability during storage is essential in metabolomics to avoid misleading conclusions or erroneous interpretations. Facing the lack of comprehensive studies on urine metabolome stability, the present work performed a follow-up of potential modiﬁcations in urinary chemical proﬁle using {LC}-{HRMS} on the basis of two parameters: the storage temperature (þ4 C, À20 C, À80 C and freeze-dried stored at À80 C) and the storage duration (5e144 days). Both {HILIC} and {RP} chromatographies have been implemented in order to globally monitor the urinary metabolome. Using an original data processing associated to univariate and multivariate data analysis, our study conﬁrms that chemical proﬁles of urine samples stored at þ4 C are very rapidly modiﬁed, as observed for instance for compounds such as:Nacetyl Glycine, Adenosine, 4-Amino benzoic acid, N-Amino diglycine, creatine, glucuronic acid, 3hydroxy-benzoic acid, pyridoxal, L-pyroglutamic acid, shikimic acid, succinic acid, thymidine, trigonelline and valeryl-carnitine, while it also demonstrates that urine samples stored at À20 C exhibit a global stability over a long period with no major modiﬁcations compared to À80 C condition. This study is the ﬁrst to investigate long term stability of urine samples and report potential modiﬁcations in the urinary metabolome, using both targeted approach monitoring individually a large number (n {\textgreater} 200) of urinary metabolites and an untargeted strategy enabling assessing for global impact of storage conditions.},
	pages = {99--107},
	journaltitle = {Analytica Chimica Acta},
	author = {Laparre, Jérôme and Kaabia, Zied and Mooney, Mark and Buckley, Tom and Sherry, Mark and Le Bizec, Bruno and Dervilly-Pinel, Gaud},
	urldate = {2019-03-29},
	date = {2017-01},
	langid = {english},
	file = {Laparre et al. - 2017 - Impact of storage conditions on the urinary metabo.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\FC6RG2QV\\Laparre et al. - 2017 - Impact of storage conditions on the urinary metabo.pdf:application/pdf}
}

@article{halloum_apci_2017,
	title = {{APCI} as an innovative ionization mode compared with {EI} and {CI} for the analysis of a large range of organophosphate esters using {GC}-{MS}/{MS}: Analysis of {OPEs} via {APCI}, {EI}, and {CI} by {GC}-{MS}/{MS}},
	volume = {52},
	issn = {10765174},
	url = {http://doi.wiley.com/10.1002/jms.3899},
	doi = {10.1002/jms.3899},
	shorttitle = {{APCI} as an innovative ionization mode compared with {EI} and {CI} for the analysis of a large range of organophosphate esters using {GC}-{MS}/{MS}},
	pages = {54--61},
	number = {1},
	journaltitle = {Journal of Mass Spectrometry},
	author = {Halloum, Wafaa and Cariou, Ronan and Dervilly-Pinel, Gaud and Jaber, Farouk and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2017-01},
	langid = {english},
	file = {Halloum et al. - 2017 - APCI as an innovative ionization mode compared wit.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\GDSWJ7YS\\Halloum et al. - 2017 - APCI as an innovative ionization mode compared wit.pdf:application/pdf}
}

@article{cesbron_aminoaciduria_2017,
	title = {Aminoaciduria Caused by Fanconi Syndrome in a Heifer},
	volume = {31},
	issn = {08916640},
	url = {http://doi.wiley.com/10.1111/jvim.14605},
	doi = {10.1111/jvim.14605},
	pages = {598--603},
	number = {2},
	journaltitle = {Journal of Veterinary Internal Medicine},
	author = {Cesbron, N. and Dorso, L. and Royer, A.-L. and Dervilly-Pinel, G. and Hervé, J.},
	urldate = {2019-03-29},
	date = {2017-03},
	langid = {english},
	file = {Cesbron et al. - 2017 - Aminoaciduria Caused by Fanconi Syndrome in a Heif.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\6C4DD4DX\\Cesbron et al. - 2017 - Aminoaciduria Caused by Fanconi Syndrome in a Heif.pdf:application/pdf}
}

@article{antignac_country-specific_2016,
	title = {Country-specific chemical signatures of persistent organic pollutants ({POPs}) in breast milk of French, Danish and Finnish women},
	volume = {218},
	issn = {02697491},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0269749116306443},
	doi = {10.1016/j.envpol.2016.07.069},
	pages = {728--738},
	journaltitle = {Environmental Pollution},
	author = {Antignac, J.P. and Main, K.M. and Virtanen, H.E. and Boquien, C.Y. and Marchand, P. and Venisseau, A. and Guiffard, I. and Bichon, E. and Wohlfahrt-Veje, C. and Legrand, A. and Boscher, C. and Skakkebæk, Niels E. and Toppari, J. and Le Bizec, B.},
	urldate = {2019-03-29},
	date = {2016-11},
	langid = {english},
	file = {Antignac et al. - 2016 - Country-specific chemical signatures of persistent.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\V5I7RCEQ\\Antignac et al. - 2016 - Country-specific chemical signatures of persistent.pdf:application/pdf}
}

@article{antignac_country-specific_2016-1,
	title = {Country-specific chemical signatures of persistent organic pollutants ({POPs}) in breast milk of French, Danish and Finnish women},
	volume = {218},
	issn = {02697491},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0269749116306443},
	doi = {10.1016/j.envpol.2016.07.069},
	abstract = {The present study compares concentrations and chemical proﬁles of an extended range of persistent organic pollutants (dioxins, polychlorobiphenyls, brominated ﬂame retardants and organochlorine pesticides) in breast milk samples from French (n ¼ 96), Danish (n ¼ 438) and Finnish (n ¼ 22) women. Median exposure levels observed in French women ({WHO}-{TEQ}2005 {PCDD}/F ¼ 6.1 pg/g l.w., {WHO}-{TEQ}2005 dl-{PCB} ¼ 4.3 pg/g l.w., sum of 6 ndl-{PCB} ¼ 85.2 ng/g l.w., sum of 7 i-{PBDE} ¼ 1.5 ng/g l.w.) appeared overall lower than in Danish and Finnish women for all examined {POPs}, except for a-{HBCD} (2-fold higher level at 0.6 ng/g l.w.). Furthermore, the observed exposure levels of dioxins and {PCBs} were higher in Danish women ({WHO}-{TEQ}2005 {PCDD}/F ¼ 13.2 pg/g l.w., {WHO}-{TEQ}2005 dl-{PCB} ¼ 6.6 pg/g l.w., sum of 6 ndl-{PCB} ¼ 162.8 ng/g l.w.) compared to Finnish women ({WHO}-{TEQ}2005 {PCDD}/F ¼ 9.0 pg/g l.w., {WHOTEQ}2005 dl-{PCB} ¼ 4.6 pg/g l.w., sum of 6 ndl-{PCB} ¼ 104.0 ng/g l.w.), whereas the concentrations of {PBDEs} were similar for Danish and Finnish women (sum of 7 i-{PBDE} ¼ 4.9 and 5.2 ng/g l.w. respectively). The organochlorine ({OC}) pesticide contamination proﬁle, determined in a subset of French samples, was dominated by p,p’-{DDE} (56.6\%), followed by b-{HCH} (14.2\%), {HCB} (9.7\%) and dieldrin (5.2\%), while other compounds were only minor contributors ({\textless}5\%). The three countries appeared to be discriminated by the observed contamination patterns of the {PCDD}/F versus {PCB}, and the 1,2,3,6,7,8-{HxCDD} versus 1,2,3,4,7,8HxCDD ratios, in addition to the relative contributions of speciﬁc congeners to the contamination proﬁle ({PCBs} \#118 and \#156, {PBDEs} \#28, \#47, \#99 and \#153). In conclusion, unique chemical signatures were observed for each country on the basis of some {POP} congeners. Future biomonitoring studies will need to consider the high variability of individual exposure proﬁles in relation to multiple exposure sources but also physiological and metabolic differences.},
	pages = {728--738},
	journaltitle = {Environmental Pollution},
	author = {Antignac, J.P. and Main, K.M. and Virtanen, H.E. and Boquien, C.Y. and Marchand, P. and Venisseau, A. and Guiffard, I. and Bichon, E. and Wohlfahrt-Veje, C. and Legrand, A. and Boscher, C. and Skakkebæk, Niels E. and Toppari, J. and Le Bizec, B.},
	urldate = {2019-03-29},
	date = {2016-11},
	langid = {english},
	file = {Antignac et al. - 2016 - Country-specific chemical signatures of persistent.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\22SBBZU3\\Antignac et al. - 2016 - Country-specific chemical signatures of persistent.pdf:application/pdf}
}

@article{ploteau_distribution_2016,
	title = {Distribution of persistent organic pollutants in serum, omental, and parietal adipose tissue of French women with deep infiltrating endometriosis and circulating versus stored ratio as new marker of exposure},
	volume = {97},
	issn = {01604120},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0160412016303026},
	doi = {10.1016/j.envint.2016.08.011},
	pages = {125--136},
	journaltitle = {Environment International},
	author = {Ploteau, Stéphane and Antignac, Jean-Philippe and Volteau, Christelle and Marchand, Philippe and Vénisseau, Anaïs and Vacher, Vincent and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2016-12},
	langid = {english},
	file = {Ploteau et al. - 2016 - Distribution of persistent organic pollutants in s.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\9XRN5IHY\\Ploteau et al. - 2016 - Distribution of persistent organic pollutants in s.pdf:application/pdf}
}

@article{ploteau_distribution_2016-1,
	title = {Distribution of persistent organic pollutants in serum, omental, and parietal adipose tissue of French women with deep infiltrating endometriosis and circulating versus stored ratio as new marker of exposure},
	volume = {97},
	issn = {01604120},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0160412016303026},
	doi = {10.1016/j.envint.2016.08.011},
	abstract = {Several studies have assessed the potential role of environmental chemicals in the onset, growth, and/or physiopathology of endometriosis. However, their contour in terms of considered exposure markers remains limited. The present study aimed to characterize the internal exposure levels of 78 persistent organic pollutants ({POPs}, including dioxins, polychlorobiphenyls, brominated ﬂame retardants and organochlorine pesticides) in a set of 113 adult French women (45 controls, 68 cases), and to characterize the distribution of these {POPs} within three biological compartments (omental adipose tissue, parietal adipose tissue, and serum). For all targeted substances, the correlation between the concentrations measured in omental versus parietal adipose tissue was found strongly signiﬁcant (p b 0.0001). An equivalence of the measures performed in parietal and omental adipose tissue was moreover observed with median levels of 6.4 vs. 7.4 pg/g l.w. for {WHO}-{TEQ}2005 {PCDD}/F, 4.5 vs. 4.7 pg/g l.w. for {WHO}-{TEQ}2005 dl-{PCB}, 137.1 vs. 147.9 ng/g l.w. for sum of 6 ndl-{PCB}, and 2.1 vs. 2.0 ng/g l.w. for sum of 7 i-{PBDE}, respectively. The same observation was made for individual targeted {OCs} compounds. Signiﬁcant correlations were also observed between these concentrations determined in adipose tissue and those measured in serum for dioxins ({WHO}-{TEQ}2005 {PCDD}/F = 6.1 pg/g l.w), {PCBs} ({WHO}-{TEQ}2005 dl-{PCB} = 3.6 pg/ g l.w., sum of 6 ndl-{PCB} = 81.1 ng/g l.w.), and brominated ﬂame-retardants (sum of 7 i-{PBDE} = 0.9 ng/g l.w.). The circulating versus stored ratio of some exposure markers (Sum {PCDDs}, 1,2,3,6,7,8-{HxCDF}, slightly versus highly chlorinated {PCBs} ratio, {PBDE} 99 and {PBB} 153) was found statistically different for control and case individuals. These extended exposure data from deep inﬁltrating endometriosis patients are the ﬁrst ones available for France and give a new insight about the equilibrium of chemicals between storage and circulating compartments that should be further considered as new marker of exposure in the context of exposure-health relationship studies.},
	pages = {125--136},
	journaltitle = {Environment International},
	author = {Ploteau, Stéphane and Antignac, Jean-Philippe and Volteau, Christelle and Marchand, Philippe and Vénisseau, Anaïs and Vacher, Vincent and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2016-12},
	langid = {english},
	file = {Ploteau et al. - 2016 - Distribution of persistent organic pollutants in s.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VL9ECTNI\\Ploteau et al. - 2016 - Distribution of persistent organic pollutants in s.pdf:application/pdf}
}

@article{savchuk_resveratrol_2017,
	title = {Resveratrol inhibits steroidogenesis in human fetal adrenocortical cells at the end of first trimester},
	volume = {61},
	issn = {16134125},
	url = {http://doi.wiley.com/10.1002/mnfr.201600522},
	doi = {10.1002/mnfr.201600522},
	pages = {1600522},
	number = {2},
	journaltitle = {Molecular Nutrition \& Food Research},
	author = {Savchuk, Iuliia and Morvan, Marie-Line and Søeborg, Tue and Antignac, Jean-Philippe and Gemzell-Danielsson, Kristina and Le Bizec, Bruno and Söder, Olle and Svechnikov, Konstantin},
	urldate = {2019-03-29},
	date = {2017-02},
	langid = {english},
	file = {Savchuk et al. - 2017 - Resveratrol inhibits steroidogenesis in human feta.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\GH4R7GC7\\Savchuk et al. - 2017 - Resveratrol inhibits steroidogenesis in human feta.pdf:application/pdf}
}

@article{boue_development_2017,
	title = {Development and Application of a Probabilistic Risk-Benefit Assessment Model for Infant Feeding Integrating Microbiological, Nutritional, and Chemical Components: Risk-Benefit Assessment of Infant Feeding},
	volume = {37},
	issn = {02724332},
	url = {http://doi.wiley.com/10.1111/risa.12792},
	doi = {10.1111/risa.12792},
	shorttitle = {Development and Application of a Probabilistic Risk-Benefit Assessment Model for Infant Feeding Integrating Microbiological, Nutritional, and Chemical Components},
	pages = {2360--2388},
	number = {12},
	journaltitle = {Risk Analysis},
	author = {Boué, Géraldine and Cummins, Enda and Guillou, Sandrine and Antignac, Jean-Philippe and Le Bizec, Bruno and Membré, Jeanne-Marie},
	urldate = {2019-03-29},
	date = {2017-12},
	langid = {english},
	file = {Boué et al. - 2017 - Development and Application of a Probabilistic Ris.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\2LJ98C2C\\Boué et al. - 2017 - Development and Application of a Probabilistic Ris.pdf:application/pdf}
}

@article{marchand_multidimensional_2017,
	title = {Multidimensional {NMR} approaches towards highly resolved, sensitive and high-throughput quantitative metabolomics},
	volume = {43},
	issn = {09581669},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0958166916301835},
	doi = {10.1016/j.copbio.2016.08.004},
	pages = {49--55},
	journaltitle = {Current Opinion in Biotechnology},
	author = {Marchand, Jérémy and Martineau, Estelle and Guitton, Yann and Dervilly-Pinel, Gaud and Giraudeau, Patrick},
	urldate = {2019-03-29},
	date = {2017-02},
	langid = {english},
	file = {Marchand et al. - 2017 - Multidimensional NMR approaches towards highly res.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\XPVYFDWX\\Marchand et al. - 2017 - Multidimensional NMR approaches towards highly res.pdf:application/pdf}
}

@article{bichon_simultaneous_2016,
	title = {Simultaneous determination of 16 brominated flame retardants in food and feed of animal origin by fast gas chromatography coupled to tandem mass spectrometry using atmospheric pressure chemical ionisation},
	volume = {1459},
	issn = {00219673},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0021967316308937},
	doi = {10.1016/j.chroma.2016.07.003},
	abstract = {A gas chromatography tandem mass spectrometry method using atmospheric pressure chemical ionisation was developed for the monitoring of 16 brominated ﬂame retardants (7 usually monitored polybromodiphenylethers ({PBDEs}) and {BDE} \#209 and 8 additional emerging and novel {BFRs}) in food and feed of animal origin. The developed analytical method has decreased the run time by three compared to conventional strategies, using a 2.5 m column length (5\% phenyl stationary phase, 0.1 mm i.d., 0.1 ␮m f.t.), a pulsed split injection (1:5) with carrier gas helium ﬂow rate at 0.48 {mL} min−1 in one run of 20 min. For most {BFRs}, analytical data were compared with the current analytical strategy relying on {GC}/{EI}/{HRMS} (double sector, R = 10000 at 10\% valley). Performances in terms of sensitivity were found to meet the Commission recommendation (118/2014/{EC}) for {nBFRs}. {GC}/{APCI}/{MS}/{MS} represents a promising alternative for multi-{BFRs} analysis in complex matrices, in that it allows the monitoring of a wider list of contaminants in a single injection and a shorter run time.},
	pages = {120--128},
	journaltitle = {Journal of Chromatography A},
	author = {Bichon, E. and Guiffard, I. and Vénisseau, A. and Lesquin, E. and Vaccher, V. and Brosseaud, A. and Marchand, P. and Le Bizec, B.},
	urldate = {2019-03-29},
	date = {2016-08},
	langid = {english},
	file = {Bichon et al. - 2016 - Simultaneous determination of 16 brominated flame .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\KVGD2VH8\\Bichon et al. - 2016 - Simultaneous determination of 16 brominated flame .pdf:application/pdf}
}

@article{rojas_selective_2017,
	title = {Selective androgen receptor modulators: comparative excretion study of bicalutamide in bovine urine and faeces: Bicalutamide excretion in bovine urine and feces},
	volume = {9},
	issn = {19427603},
	url = {http://doi.wiley.com/10.1002/dta.2113},
	doi = {10.1002/dta.2113},
	shorttitle = {Selective androgen receptor modulators},
	pages = {1017--1025},
	number = {7},
	journaltitle = {Drug Testing and Analysis},
	author = {Rojas, Dante and Dervilly-Pinel, Gaud and Cesbron, Nora and Penot, Mylène and Sydor, Alexandre and Prévost, Stéphanie and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2017-07},
	langid = {english},
	file = {Rojas et al. - 2017 - Selective androgen receptor modulators comparativ.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\YD8MSBRZ\\Rojas et al. - 2017 - Selective androgen receptor modulators comparativ.pdf:application/pdf}
}

@article{cesbron_analytical_2017,
	title = {Analytical strategies to detect enobosarm administration in bovines},
	volume = {34},
	issn = {1944-0049, 1944-0057},
	url = {https://www.tandfonline.com/doi/full/10.1080/19440049.2016.1258122},
	doi = {10.1080/19440049.2016.1258122},
	abstract = {Selective androgen receptor modulators ({SARMs}) are a novel class of androgen receptor ligands. They are intended to exhibit the same kind of effects as androgenic drugs, like anabolic steroids, but be much more selective in their action, targeting particular tissues without any undesirable effects on others. While the main applications of these synthetic substances are for therapeutic purposes, they also have a high potential for misuse in veterinary practice and the sporting world. In order to guarantee for consumers with food from animal origin that it is free from any residues of such compounds, analytical strategies are required to ensure safe food and also to enable fair trade between producers. In this context an animal experiment involving bovines administered with enobosarm was conducted to provide the study with biological matrices. Different animal matrices (urine and faeces) were investigated to select the most appropriate matrix for use for control purposes, in terms of metabolite relevance and detection time window. Based on ultrahigh-pressure liquid chromatography ({UHPLC}) with tandem mass spectrometry ({LC}-{MS}/{MS}) this work highlighted the presence of sulfonated and glucuronated-conjugated forms of the molecule in the urine of treated animals. Enobosarm could be detected in urine up to 9 days after the administration when samples underwent phase {II} hydrolysis. Faeces was demonstrated to be the main matrix of excretion of enobosarm since values up to 500 times higher compared with urine could be detected for 21 days. There was no difference between the kinetic profiles when a deconjugation step was or was not was applied.},
	pages = {632--640},
	number = {4},
	journaltitle = {Food Additives \& Contaminants: Part A},
	author = {Cesbron, Nora and Sydor, Alexandre and Penot, Mylène and Prevost, Stéphanie and Le Bizec, Bruno and Dervilly-Pinel, Gaud},
	urldate = {2019-03-29},
	date = {2017-04-03},
	langid = {english},
	file = {Cesbron et al. - 2017 - Analytical strategies to detect enobosarm administ.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VT72YZJS\\Cesbron et al. - 2017 - Analytical strategies to detect enobosarm administ.pdf:application/pdf}
}

@article{peng_serum-based_2017,
	title = {Serum-based metabolomics characterization of pigs treated with ractopamine},
	volume = {13},
	issn = {1573-3882, 1573-3890},
	url = {http://link.springer.com/10.1007/s11306-017-1212-0},
	doi = {10.1007/s11306-017-1212-0},
	abstract = {Introduction  Ractopamine, a β-agonist used as growth promoter in livestock, is with great controversy, and it has been forbidden in most countries worldwide. However, due to economic benefits, the possibility of widespread abuse of ractopamine still exists. “Omics” strategies, based on the observation of physiological perturbations, are promising approaches to tackle drug misuse in breeding animals.},
	number = {6},
	journaltitle = {Metabolomics},
	author = {Peng, Tao and Royer, Anne-Lise and Guitton, Yann and Le Bizec, Bruno and Dervilly-Pinel, Gaud},
	urldate = {2019-03-29},
	date = {2017-06},
	langid = {english},
	file = {Peng et al. - 2017 - Serum-based metabolomics characterization of pigs .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\8FTCRXPV\\Peng et al. - 2017 - Serum-based metabolomics characterization of pigs .pdf:application/pdf}
}

@article{prevost_dispositif_nodate,
	title = {Dispositif de surveillance des promoteurs de croissance},
	pages = {17},
	author = {Prévost, Stéphanie and Sérée, Ludivine and Sittisack, Parina and Dervilly-Pinel, Gaud and Bizec, Bruno Le and Fournet, Isabelle},
	langid = {french},
	file = {Prévost et al. - Dispositif de surveillance des promoteurs de crois.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\92VYUK63\\Prévost et al. - Dispositif de surveillance des promoteurs de crois.pdf:application/pdf}
}

@article{ganzleben_human_2017,
	title = {Human biomonitoring as a tool to support chemicals regulation in the European Union},
	volume = {220},
	issn = {14384639},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S1438463916303613},
	doi = {10.1016/j.ijheh.2017.01.007},
	pages = {94--97},
	number = {2},
	journaltitle = {International Journal of Hygiene and Environmental Health},
	author = {Ganzleben, Catherine and Antignac, Jean-Philippe and Barouki, Robert and Castaño, Argelia and Fiddicke, Ulrike and Klánová, Jana and Lebret, Erik and Olea, Nicolas and Sarigiannis, Dimosthenis and Schoeters, Greet R. and Sepai, Ovnair and Tolonen, Hanna and Kolossa-Gehring, Marike},
	urldate = {2019-03-29},
	date = {2017-03},
	langid = {english},
	file = {Ganzleben et al. - 2017 - Human biomonitoring as a tool to support chemicals.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\8MKBV2TU\\Ganzleben et al. - 2017 - Human biomonitoring as a tool to support chemicals.pdf:application/pdf}
}

@article{roullier_time_2016,
	title = {Time Dependency of Chemodiversity and Biosynthetic Pathways: An {LC}-{MS} Metabolomic Study of Marine-Sourced Penicillium},
	volume = {14},
	issn = {1660-3397},
	url = {http://www.mdpi.com/1660-3397/14/5/103},
	doi = {10.3390/md14050103},
	shorttitle = {Time Dependency of Chemodiversity and Biosynthetic Pathways},
	abstract = {This work aimed at studying metabolome variations of marine fungal strains along their growth to highlight the importance of the parameter “time” for new natural products discovery. An untargeted time-scale metabolomic study has been performed on two different marine-derived Penicillium strains. They were cultivated for 18 days and their crude extracts were analyzed by {HPLC}-{DAD}-{HRMS} (High Performance Liquid Chromatography-Diode Array Detector-High Resolution Mass Spectrometry) each day. With the example of griseofulvin biosynthesis, a pathway shared by both strains, this work provides a new approach to study biosynthetic pathway regulations, which could be applied to other metabolites and more particularly new ones. Moreover, the results of this study emphasize the interest of such an approach for the discovery of new chemical entities. In particular, at every harvesting time, previously undetected features were observed in the {LC}-{MS} (Liquid Chromatography-Mass Spectrometry) data. Therefore, harvesting times for metabolite extraction should be performed at different time points to access the hidden metabolome.},
	pages = {103},
	number = {5},
	journaltitle = {Marine Drugs},
	author = {Roullier, Catherine and Bertrand, Samuel and Blanchet, Elodie and Peigné, Mathilde and Robiou du Pont, Thibaut and Guitton, Yann and Pouchus, Yves and Grovel, Olivier},
	urldate = {2019-03-29},
	date = {2016-05-21},
	langid = {english},
	file = {Roullier et al. - 2016 - Time Dependency of Chemodiversity and Biosynthetic.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\A5XG3FD9\\Roullier et al. - 2016 - Time Dependency of Chemodiversity and Biosynthetic.pdf:application/pdf}
}

@article{bouhlel_solid-phase_2017,
	title = {Solid-phase microextraction set-up for the analysis of liver volatolome to detect livestock exposure to micropollutants},
	volume = {1497},
	issn = {00219673},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0021967317303576},
	doi = {10.1016/j.chroma.2017.03.008},
	pages = {9--18},
	journaltitle = {Journal of Chromatography A},
	author = {Bouhlel, Jihéne and Ratel, Jérémy and Abouelkaram, Said and Mercier, Frédéric and Travel, Angelique and Baéza, Elisabeth and Jondreville, Catherine and Dervilly-Pinel, Gaud and Marchand, Philippe and Le Bizec, Bruno and Dubreil, Estelle and Mompelat, Sophie and Verdon, Eric and Inthavong, Chanthadary and Guérin, Thierry and Rutledge, Douglas N. and Engel, Erwan},
	urldate = {2019-03-29},
	date = {2017-05},
	langid = {english},
	file = {Bouhlel et al. - 2017 - Solid-phase microextraction set-up for the analysi.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\N76ESTXP\\Bouhlel et al. - 2017 - Solid-phase microextraction set-up for the analysi.pdf:application/pdf}
}

@article{planche_effects_2017,
	title = {Effects of pan cooking on micropollutants in meat},
	volume = {232},
	issn = {03088146},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0308814617304235},
	doi = {10.1016/j.foodchem.2017.03.049},
	pages = {395--404},
	journaltitle = {Food Chemistry},
	author = {Planche, Christelle and Ratel, Jérémy and Blinet, Patrick and Mercier, Frédéric and Angénieux, Magaly and Chafey, Claude and Zinck, Julie and Marchond, Nathalie and Chevolleau, Sylvie and Marchand, Philippe and Dervilly-Pinel, Gaud and Guérin, Thierry and Debrauwer, Laurent and Engel, Erwan},
	urldate = {2019-03-29},
	date = {2017-10},
	langid = {english},
	file = {Planche et al. - 2017 - Effects of pan cooking on micropollutants in meat.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\MUCIVDGM\\Planche et al. - 2017 - Effects of pan cooking on micropollutants in meat.pdf:application/pdf}
}

@article{jondreville_accumulation_2017,
	title = {Accumulation of α-hexabromocyclododecane (α-{HBCDD}) in tissues of fast- and slow-growing broilers (Gallus domesticus)},
	volume = {178},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0045653517304277},
	doi = {10.1016/j.chemosphere.2017.03.064},
	abstract = {The aim of the current study was to describe the fate of ingested a-hexabromocyclododecane (a-{HBCDD}) in fast-growing ({FG}) and slow-growing ({SG}) broilers, through an exposure to a dietary concentration of 50 ng a-{HBCDD} {gÀ}1 feed during 42 and 84 days, respectively. Depuration parameters were assessed in {SG} broilers successively exposed during 42 days and depurated during 42 days. At market age, {SG} broilers had ingested 42\% more feed than {FG} broilers, while their body weight gain per g of feed ingested was 34\% lower. No isomerization of a- to b- or g-{HBCDD} forms occurred, while {OH}-{HBCDD} was identiﬁed as a product of a-{HBCDD} metabolism. Irrespective of the strain, abdominal fat displayed the highest a-{HBCDD} concentration on a lipid weight basis, followed leg muscles and then breast muscle, liver and plasma. The accumulation ratios of a-{HBCDD} were slightly higher in {SG} (6.7, 2.1, 2.6 and 9.9 in leg muscles, breast muscle, liver and abdominal fat, respectively) than in {FG} broilers (5.2, 2.2, 1.1 and 8.4, respectively). The elimination half-lives in {SG} broilers were 20, 12 and 19 d in leg muscles, breast muscle and abdominal fat, respectively, to which dilution through growth contributed for around 50\%. The overall assimilation efﬁciency of a-{HBCDD} was estimated at 58 and 50\% in {FG} and {SG} broilers, respectively, while 22 and 17\% of a-{HBCDD} ingested were estimated to be eliminated in excreta as metabolites.},
	pages = {424--431},
	journaltitle = {Chemosphere},
	author = {Jondreville, Catherine and Cariou, Ronan and Méda, Bertrand and Dominguez-Romero, Elena and Omer, Elsa and Dervilly-Pinel, Gaud and Le Bizec, Bruno and Travel, Angélique and Baéza, Elisabeth},
	urldate = {2019-03-29},
	date = {2017-07},
	langid = {english},
	file = {Jondreville et al. - 2017 - Accumulation of α-hexabromocyclododecane (α-HBCDD).pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\7ESXNDVV\\Jondreville et al. - 2017 - Accumulation of α-hexabromocyclododecane (α-HBCDD).pdf:application/pdf}
}

@article{hennig_steroid_2018,
	title = {Steroid hormone profiling in human breast adipose tissue using semi-automated purification and highly sensitive determination of estrogens by {GC}-{APCI}-{MS}/{MS}},
	volume = {410},
	issn = {1618-2642, 1618-2650},
	url = {http://link.springer.com/10.1007/s00216-017-0717-8},
	doi = {10.1007/s00216-017-0717-8},
	pages = {259--275},
	number = {1},
	journaltitle = {Analytical and Bioanalytical Chemistry},
	author = {Hennig, Kristin and Antignac, Jean Philippe and Bichon, Emmanuelle and Morvan, Marie-Line and Miran, Isabelle and Delaloge, Suzette and Feunteun, Jean and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2018-01},
	langid = {english},
	file = {Hennig et al. - 2018 - Steroid hormone profiling in human breast adipose .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\VZ9WISG8\\Hennig et al. - 2018 - Steroid hormone profiling in human breast adipose .pdf:application/pdf}
}

@article{guitton_create_2017,
	title = {Create, run, share, publish, and reference your {LC}–{MS}, {FIA}–{MS}, {GC}–{MS}, and {NMR} data analysis workflows with the Workflow4Metabolomics 3.0 Galaxy online infrastructure for metabolomics},
	volume = {93},
	issn = {13572725},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S1357272517301577},
	doi = {10.1016/j.biocel.2017.07.002},
	abstract = {Metabolomics is a key approach in modern functional genomics and systems biology. Due to the complexity of metabolomics data, the variety of experimental designs, and the multiplicity of bioinformatics tools, providing experimenters with a simple and eﬃcient resource to conduct comprehensive and rigorous analysis of their data is of utmost importance. In 2014, we launched the Workﬂow4Metabolomics (W4M; http:// workﬂow4metabolomics.org) online infrastructure for metabolomics built on the Galaxy environment, which oﬀers user-friendly features to build and run data analysis workﬂows including preprocessing, statistical analysis, and annotation steps. Here we present the new W4M 3.0 release, which contains twice as many tools as the ﬁrst version, and provides two features which are, to our knowledge, unique among online resources. First, data from the four major metabolomics technologies (i.e., {LC}–{MS}, {FIA}–{MS}, {GC}–{MS}, and {NMR}) can be analyzed on a single platform. By using three studies in human physiology, alga evolution, and animal toxicology, we demonstrate how the 40 available tools can be easily combined to address biological issues. Second, the full analysis (including the workﬂow, the parameter values, the input data and output results) can be referenced with a permanent digital object identiﬁer ({DOI}). Publication of data analyses is of major importance for robust and reproducible science. Furthermore, the publicly shared workﬂows are of high-value for e-learning and training. The Workﬂow4Metabolomics 3.0 e-infrastructure thus not only oﬀers a unique online environment for analysis of data from the main metabolomics technologies, but it is also the ﬁrst reference repository for metabolomics workﬂows.},
	pages = {89--101},
	journaltitle = {The International Journal of Biochemistry \& Cell Biology},
	author = {Guitton, Yann and Tremblay-Franco, Marie and Le Corguillé, Gildas and Martin, Jean-François and Pétéra, Mélanie and Roger-Mele, Pierrick and Delabrière, Alexis and Goulitquer, Sophie and Monsoor, Misharl and Duperier, Christophe and Canlet, Cécile and Servien, Rémi and Tardivel, Patrick and Caron, Christophe and Giacomoni, Franck and Thévenot, Etienne A.},
	urldate = {2019-03-29},
	date = {2017-12},
	langid = {english},
	file = {Guitton et al. - 2017 - Create, run, share, publish, and reference your LC.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\RMIKW6FE\\Guitton et al. - 2017 - Create, run, share, publish, and reference your LC.pdf:application/pdf}
}

@article{martin_agnoux_maternal_2018,
	title = {Maternal protein restriction during lactation induces early and lasting plasma metabolomic and hepatic lipidomic signatures of the offspring in a rodent programming model},
	volume = {55},
	issn = {09552863},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0955286317304345},
	doi = {10.1016/j.jnutbio.2017.11.009},
	abstract = {Perinatal undernutrition affects not only fetal and neonatal growth but also adult health outcome, as suggested by the metabolic imprinting concept. However, the exact mechanisms underlying offspring metabolic adaptations are not yet fully understood. Specifically, it remains unclear whether the gestation or the lactation is the more vulnerable period to modify offspring metabolic flexibility. We investigated in a rodent model of intrauterine growth restriction ({IUGR}) induced by maternal protein restriction (R) during gestation which time window of maternal undernutrition (gestation, lactation or gestation–lactation) has more impact on the male offspring metabolomics phenotype. Plasma metabolome and hepatic lipidome of offspring were characterized through suckling period and at adulthood using liquid chromatography–high-resolution mass spectrometry. Multivariate analysis of these fingerprints highlighted a persistent metabolomics signature in rats suckled by R dams, with a clear-cut discrimination from offspring fed by control (C) dams. Pups submitted to a nutritional switch at birth presented a metabolomics signature clearly distinct from that of pups nursed by dams maintained on a consistent perinatal diet. Control rats suckled by R dams presented transiently higher branched-chain amino acid ({BCAA}) oxidation during lactation besides increased fatty acid ({FA}) β-oxidation, associated with preserved insulin sensitivity and lesser fat accretion that persisted throughout their life. In contrast, {IUGR} rats displayed permanently impaired β-oxidation, associated to increased glucose or {BCAA} oxidation at adulthood, depending on the fact that pups experienced slow postnatal or catch-up growth, as suckled by R or C dams, respectively. Taken together, these findings provide evidence for a significant contribution of the lactation period in metabolic programming.},
	pages = {124--141},
	journaltitle = {The Journal of Nutritional Biochemistry},
	author = {Martin Agnoux, Aurore and El Ghaziri, Angélina and Moyon, Thomas and Pagniez, Anthony and David, Agnès and Simard, Gilles and Parnet, Patricia and Qannari, El Mostafa and Darmaun, Dominique and Antignac, Jean-Philippe and Alexandre-Gouabau, Marie-Cécile},
	urldate = {2019-03-29},
	date = {2018-05},
	langid = {english},
	file = {Martin Agnoux et al. - 2018 - Maternal protein restriction during lactation indu.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\5QN64TFN\\Martin Agnoux et al. - 2018 - Maternal protein restriction during lactation indu.pdf:application/pdf}
}

@article{stella_metabolomics_2017,
	title = {Metabolomics analysis of liver reveals profile disruption in bovines upon steroid treatment},
	volume = {13},
	issn = {1573-3882, 1573-3890},
	url = {http://link.springer.com/10.1007/s11306-017-1220-0},
	doi = {10.1007/s11306-017-1220-0},
	abstract = {Introduction  The surveillance of illegal anabolic practices in bovine meat production is necessary to guarantee consumers’ health. Screening strategies based on the recognition of indirect biological effects are considered by the community as promising tools to overcome some limitations of classical analytical methods and might therefore concur to ensure safer food for the consumer.},
	number = {7},
	journaltitle = {Metabolomics},
	author = {Stella, Roberto and Dervilly-Pinel, Gaud and Bovo, Davide and Mastrorilli, Eleonora and Royer, Anne-Lise and Angeletti, Roberto and Le Bizec, Bruno and Biancotto, Giancarlo},
	urldate = {2019-03-29},
	date = {2017-07},
	langid = {english},
	file = {Stella et al. - 2017 - Metabolomics analysis of liver reveals profile dis.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\5SR4FK87\\Stella et al. - 2017 - Metabolomics analysis of liver reveals profile dis.pdf:application/pdf}
}

@article{royer_lapproche_2017,
	title = {L’approche métabolomique par spectrométrie de masse : évidences, incertitudes et points critiques},
	abstract = {Metabolomics is a methodological approach emerged in the late 2 000s in line with other «- omics» : genomics, transcriptomics and proteomics. Like these other approaches, metabolomics is used in various fields and aims at measuring simultaneously all small endogenous metabolites ({\textless} 1 000 Da) impacted by a disturbance affecting a given biological system. Ultimately, these measures give insights in differences, often tenuous, between different states of a biological system. To achieve with confidence such a degree of sensitivity, it is necessary to master all the different steps of the approach. Metabolomics involves several disciplines (biology, chemistry, bioinformatics, and statistics) and such diversity multiplies the possibilities of confounding factors to arise and thus increases the sources of results misinterpretation. The expertise acquired over the years by researchers from the different areas involved in metabolomics can be briefly summarized in a generic workflow that from the experimental design to the biological interpretation of the data, intends at minimizing all sources of undesirable variability. All this is done in order to respond to this «simple» question : are the differences observed at the end of the process really and only linked to a biological reality ? Here, we discuss the first steps of a metabolomics study: experimental design, sample preparation, data acquisition and pre-processing, with the primary objective to provide clues for a critical assessment of the results and to provide the foundation for the successful implementation of a metabolomics study, in other words, a study meeting the quality criteria for an unbiased interpretation. Examples of illustration mainly refer to studies of mass spectrometric based untargeted metabolomics in the field of chemical food safety.},
	pages = {8},
	author = {Royer, Anne-Lise and Escourrou, Antoine and Guitton, Yann and Dervilly-Pinel, Gaud and Antignac, Jean-Philippe and Bizec, Bruno {LE}},
	date = {2017},
	langid = {french},
	file = {Royer et al. - 2017 - L’approche métabolomique par spectrométrie de mass.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\Q3A785G6\\Royer et al. - 2017 - L’approche métabolomique par spectrométrie de mass.pdf:application/pdf}
}

@article{omer_enantiomer-specific_2017,
	title = {Enantiomer-specific accumulation and depuration of α-hexabromocyclododecane (α-{HBCDD}) in chicken ( Gallus gallus ) as a tool to identify contamination sources},
	volume = {180},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0045653517305544},
	doi = {10.1016/j.chemosphere.2017.04.031},
	pages = {365--372},
	journaltitle = {Chemosphere},
	author = {Omer, Elsa and Cariou, Ronan and Huneau-Salaün, Adeline and Dervilly-Pinel, Gaud and Baéza, Élisabeth and Travel, Angélique and Le Bouquin, Sophie and Jondreville, Catherine and Le Bizec, Bruno},
	urldate = {2019-03-29},
	date = {2017-08},
	langid = {english},
	file = {Omer et al. - 2017 - Enantiomer-specific accumulation and depuration of.pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\N6IH8PTR\\Omer et al. - 2017 - Enantiomer-specific accumulation and depuration of.pdf:application/pdf}
}

@article{jondreville_hens_2017,
	title = {Hens can ingest extruded polystyrene in rearing buildings and lay eggs contaminated with hexabromocyclododecane},
	volume = {186},
	issn = {00456535},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0045653517311682},
	doi = {10.1016/j.chemosphere.2017.07.117},
	abstract = {The overall concentration of hexabromocyclododecane ({HBCDD}) in eggs is low although abnormally high concentrations exceeding 3000 ng {gÀ}1 lw have been reported. In order to test whether these contaminations may originate from the ingestion of insulating materials in rearing buildings, a group of 55 hens raised in a collective cage was provided with a 64-g piece of extruded polystyrene ({XPS}, 2.59\% {HBCDD} of which 75, 15 and 10\% as a-, b- and g-{HBCDD}, respectively). Hens entirely consumed the piece within 3 days, leading to a mean daily exposure of 4.7 mg {HBCDD} per kg body weight. Whole egg {HBCDD} concentration reached a maximum of 1037 ng {HBCDD} {gÀ}1 fresh weight (fw), recorded 2 days after the piece had disappeared, and decreased down to 86 ng {gÀ}1 fw within the 19 following days. In all these samples, {HBCDD} was made of 98.7 ± 0.7 and 1.3 ± 0.6\% a- and b-{HBCDD}, respectively, and 0.1\% g-{HBCDD} when quantiﬁed; it was enriched in (À)a- and (þ)b-{HBCDD} with enantiomeric fractions of 0.438 ± 0.009 and 0.579 ± 0.030, respectively. {HBCDD} was quantiﬁed in all the individual eggs collected the last day of experiment at concentrations ranging between 0.47 and 1361 ng {gÀ}1 fw, according to a lognormal distribution. The ingestion of {XPS} in degraded rearing buildings is thus a plausible cause of on-farm egg contamination by {HBCDD} which should be strictly avoided.},
	pages = {62--67},
	journaltitle = {Chemosphere},
	author = {Jondreville, Catherine and