text:
B and Nichols, A I",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  12,
  number  =  5,
  pages   = "545--558",
  year    =  1984
}

@ARTICLE{Fuseau1984-zv,
  title   = "Simultaneous modeling of pharmacokinetics and pharmacodynamics
             with a nonparametric pharmacodynamic model",
  author  = "Fuseau, E and Sheiner, L B",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  35,
  number  =  6,
  pages   = "733--741",
  year    =  1984
}

@ARTICLE{Sheiner1984-qt,
  title   = "Analysis of pharmacokinetic data using parametric models--1:
             Regression models",
  author  = "Sheiner, L B",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  12,
  number  =  1,
  pages   = "93--117",
  year    =  1984
}

@ARTICLE{Sheiner1984-ox,
  title   = "The population approach to pharmacokinetic data analysis:
             rationale and standard data analysis methods",
  author  = "Sheiner, L B",
  journal = "Drug Metab. Rev.",
  volume  =  15,
  number  = "1-2",
  pages   = "153--171",
  year    =  1984
}

@ARTICLE{Peck1984-th,
  title   = "The problem of choosing weights in nonlinear regression analysis
             of pharmacokinetic data",
  author  = "Peck, C C and Sheiner, L B and Nichols, A I",
  journal = "Drug Metab. Rev.",
  volume  =  15,
  number  = "1-2",
  pages   = "133--148",
  year    =  1984
}

@ARTICLE{Sheiner1984-fn,
  title   = "Experience with {NONMEM}: analysis of routine phenytoin clinical
             pharmacokinetic data",
  author  = "Sheiner, L B and Grasela, T H",
  journal = "Drug Metab. Rev.",
  volume  =  15,
  number  = "1-2",
  pages   = "293--303",
  year    =  1984
}

@ARTICLE{Grasela1983-cv,
  title   = "Steady-state pharmacokinetics of phenytoin from routinely
             collected patient data",
  author  = "Grasela, T H and Sheiner, L B and Rambeck, B and Boenigk, H E and
             Dunlop, A and Mullen, P W and Wadsworth, J and Richens, A and
             Ishizaki, T and Chiba, K",
  journal = "Clin. Pharmacokinet.",
  volume  =  8,
  number  =  4,
  pages   = "355--364",
  year    =  1983
}

@ARTICLE{Sheiner1983-hz,
  title   = "Evaluation of methods for estimating population pharmacokinetic
             parameters. {III}. Monoexponential model: routine clinical
             pharmacokinetic data",
  author  = "Sheiner, L B and Beal, S L",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  11,
  number  =  3,
  pages   = "303--319",
  year    =  1983
}

@ARTICLE{Sheiner1982-sf,
  title   = "Bayesian individualization of pharmacokinetics: simple
             implementation and comparison with non-Bayesian methods",
  author  = "Sheiner, L B and Beal, S L",
  journal = "J. Pharm. Sci.",
  volume  =  71,
  number  =  12,
  pages   = "1344--1348",
  year    =  1982
}

@ARTICLE{Cahalan1982-yi,
  title   = "A noninvasive in vivo method of assessing the kinetics of
             halothane metabolism in humans",
  author  = "Cahalan, M K and Johnson, B H and Eger, E I and Sheiner, L B and
             Richardson, C A and Varner, J K and Severinghaus, J W",
  journal = "Anesthesiology",
  volume  =  57,
  number  =  4,
  pages   = "298--302",
  year    =  1982
}

@ARTICLE{Carlson1982-cp,
  title   = "Clearance of serum creatine kinase activity",
  author  = "Carlson, C J and Meister, W and Emilson, B and Sheiner, L B and
             Rapaport, E",
  journal = "Cardiovasc. Res.",
  volume  =  16,
  number  =  2,
  pages   = "66--70",
  year    =  1982
}

@ARTICLE{Beal1982-wp,
  title   = "Estimating population kinetics",
  author  = "Beal, S L and Sheiner, L B",
  journal = "Crit. Rev. Biomed. Eng.",
  volume  =  8,
  number  =  3,
  pages   = "195--222",
  year    =  1982
}

@ARTICLE{Holford1982-xk,
  title   = "Kinetics of pharmacologic response",
  author  = "Holford, N H and Sheiner, L B",
  journal = "Pharmacol. Ther. Dent.",
  volume  =  16,
  number  =  2,
  pages   = "143--166",
  year    =  1982
}

@ARTICLE{Holford1981-fq,
  title   = "Understanding the dose-effect relationship: clinical application
             of pharmacokinetic-pharmacodynamic models",
  author  = "Holford, N H and Sheiner, L B",
  journal = "Clin. Pharmacokinet.",
  volume  =  6,
  number  =  6,
  pages   = "429--453",
  year    =  1981
}

@ARTICLE{Sheiner1981-zw,
  title   = "Some suggestions for measuring predictive performance",
  author  = "Sheiner, L B and Beal, S L",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  9,
  number  =  4,
  pages   = "503--512",
  year    =  1981
}

@ARTICLE{Holford1981-ce,
  title   = "The effect of quinidine and its metabolites on the
             electrocardiogram and systolic time intervals:
             concentration--effect relationships",
  author  = "Holford, N H and Coates, P E and Guentert, T W and Riegelman, S
             and Sheiner, L B",
  journal = "Br. J. Clin. Pharmacol.",
  volume  =  11,
  number  =  2,
  pages   = "187--195",
  year    =  1981
}

@ARTICLE{Sheiner1981-ep,
  title   = "A standard approach to compiling clinical pharmacokinetic data",
  author  = "Sheiner, L B and Benet, L Z and Pagliaro, L A",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  9,
  number  =  1,
  pages   = "59--127",
  year    =  1981
}

@ARTICLE{Wheeler1981-kv,
  title   = "A clinical evaluation of various delta check methods",
  author  = "Wheeler, L A and Sheiner, L B",
  journal = "Clin. Chem.",
  volume  =  27,
  number  =  1,
  pages   = "5--9",
  year    =  1981
}

@ARTICLE{Holford1981-js,
  title   = "Pharmacokinetic and pharmacodynamic modeling in vivo",
  author  = "Holford, N H and Sheiner, L B",
  journal = "CRC Crit. Rev. Bioeng.",
  volume  =  5,
  number  =  4,
  pages   = "273--322",
  year    =  1981
}

@ARTICLE{Stanski1980-pe,
  title   = "Time-dependent increase in sensitivity to d-tubocurarine during
             enflurane anesthesia in man",
  author  = "Stanski, D R and Ham, J and Miller, R D and Sheiner, L B",
  journal = "Anesthesiology",
  volume  =  52,
  number  =  6,
  pages   = "483--487",
  year    =  1980
}

@ARTICLE{Iavarone2003-zi,
  title   = "An application of nonlinear mixed-effects modeling to
             pharmacokinetic data exhibiting nonlinear and time-dependent
             behavior",
  author  = "Iavarone, L and Gomeni, R",
  journal = "J. Pharm. Sci.",
  volume  =  92,
  number  =  1,
  pages   = "27--34",
  year    =  2003
}

@ARTICLE{Whiting1980-zg,
  title   = "Quantitative analysis of the disopyramide concentration-effect
             relationship",
  author  = "Whiting, B and Holford, N H and Sheiner, L B",
  journal = "Br. J. Clin. Pharmacol.",
  volume  =  9,
  number  =  1,
  pages   = "67--75",
  year    =  1980
}

@ARTICLE{Sheiner1979-zk,
  title   = "The performance of delta check methods",
  author  = "Sheiner, L B and Wheeler, L A and Moore, J K",
  journal = "Clin. Chem.",
  volume  =  25,
  number  =  12,
  pages   = "2034--2037",
  year    =  1979
}

@ARTICLE{Stanski1979-if,
  title   = "Pharmacokinetics and pharmacodynamics of d-tubocurarine during
             nitrous oxide-narcotic and halothane anesthesia in man",
  author  = "Stanski, D R and Ham, J and Miller, R D and Sheiner, L B",
  journal = "Anesthesiology",
  volume  =  51,
  number  =  3,
  pages   = "235--241",
  year    =  1979
}

@ARTICLE{Sheiner1979-qg,
  title   = "Forecasting individual pharmacokinetics",
  author  = "Sheiner, L B and Beal, S and Rosenberg, B and Marathe, V V",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  26,
  number  =  3,
  pages   = "294--305",
  year    =  1979
}

@ARTICLE{Bonate2004-xj,
  title   = "Population pharmacokinetics of {APOMINE}: a meta-analysis in
             cancer patients and healthy males",
  author  = "Bonate, P L and Floret, S and Bentzen, C",
  journal = "Br. J. Clin. Pharmacol.",
  volume  =  58,
  number  =  2,
  pages   = "142--155",
  year    =  2004
}

@ARTICLE{Stanski1979-nk,
  title   = "Pharmacokinetics and dynamics of muscle relaxants",
  author  = "Stanski, D R and Sheiner, L B",
  journal = "Anesthesiology",
  volume  =  51,
  number  =  2,
  pages   = "103--105",
  year    =  1979
}

@ARTICLE{Wheeler1979-tb,
  title   = "Clinical estimation of creatinine clearance",
  author  = "Wheeler, L A and Sheiner, L B",
  journal = "Am. J. Clin. Pathol.",
  volume  =  72,
  number  =  1,
  pages   = "27--32",
  year    =  1979
}

@ARTICLE{Ham1979-fx,
  title   = "Dosage-schedule independence of d-tubocurarine pharmacokinetics
             and pharmacodynamics, and recovery of neuromuscular function",
  author  = "Ham, J and Miller, R D and Sheiner, L B and Matteo, R S",
  journal = "Anesthesiology",
  volume  =  50,
  number  =  6,
  pages   = "528--533",
  year    =  1979
}

@ARTICLE{Sheiner1979-be,
  title   = "Simultaneous modeling of pharmacokinetics and pharmacodynamics:
             application to d-tubocurarine",
  author  = "Sheiner, L B and Stanski, D R and Vozeh, S and Miller, R D and
             Ham, J",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  25,
  number  =  3,
  pages   = "358--371",
  year    =  1979
}

@ARTICLE{Silber1979-zr,
  title   = "Spironolactone-associated digoxin radioimmunoassay interference",
  author  = "Silber, B and Sheiner, L B and Powers, J L and Winter, M E and
             Sadee, W",
  journal = "Clin. Chem.",
  volume  =  25,
  number  =  1,
  pages   = "48--50",
  year    =  1979
}

@ARTICLE{Ravenscroft1978-xo,
  title   = "Saliva lithium concentrations in the management of lithium therapy",
  author  = "Ravenscroft, P and Vozeh, S and Weinstein, M and Sheiner, L B",
  journal = "Arch. Gen. Psychiatry",
  volume  =  35,
  number  =  9,
  pages   = "1123--1127",
  year    =  1978
}

@ARTICLE{Powell1978-xo,
  title   = "Theophylline disposition in acutely ill hospitalized patients. The
             effect of smoking, heart failure, severe airway obstruction, and
             pneumonia",
  author  = "Powell, J R and Vozeh, S and Hopewell, P and Costello, J and
             Sheiner, L B and Riegelman, S",
  journal = "Am. Rev. Respir. Dis.",
  volume  =  118,
  number  =  2,
  pages   = "229--238",
  year    =  1978
}

@ARTICLE{Sheiner1978-ti,
  title   = "The algorithm in medicine",
  author  = "Sheiner, L B and Brecher, G and Wheeler, L A",
  journal = "JAMA",
  volume  =  239,
  number  =  19,
  pages   = "1957--1958",
  year    =  1978
}

@ARTICLE{Sheiner1978-ys,
  title   = "The utility function of antihypertensive therapy",
  author  = "Sheiner, L B and Melmon, K L",
  journal = "Ann. N. Y. Acad. Sci.",
  volume  =  304,
  pages   = "112--127",
  year    =  1978
}

@ARTICLE{Wheeler1977-yy,
  title   = "Clinical laboratory use in the evaluation of anemia",
  author  = "Wheeler, L A and Brecher, G and Sheiner, L B",
  journal = "JAMA",
  volume  =  238,
  number  =  25,
  pages   = "2709--2714",
  year    =  1977
}

@ARTICLE{Martin1977-wi,
  title   = "The clinical pharmacokinetics of phenytoin",
  author  = "Martin, E and Tozer, T N and Sheiner, L B and Riegelman, S",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  5,
  number  =  6,
  pages   = "579--596",
  year    =  1977
}

@ARTICLE{Berman1977-xx,
  title   = "Differential effects of digoxin at comparable concentrations in
             tissues of fetal and adult sheep",
  author  = "Berman, W., Jr and Ravenscroft, P J and Sheiner, L B and Heymann,
             M A and Melmon, K L and Rudolph, A M",
  journal = "Circ. Res.",
  volume  =  41,
  number  =  5,
  pages   = "635--642",
  year    =  1977
}

@ARTICLE{Sheiner1977-oh,
  title   = "Estimation of population characteristics of pharmacokinetic
             parameters from routine clinical data",
  author  = "Sheiner, L B and Rosenberg, B and Marathe, V V",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  5,
  number  =  5,
  pages   = "445--479",
  year    =  1977
}

@ARTICLE{Holford1977-mt,
  title   = "The digoxin concentration: before and after the fact",
  author  = "Holford, N and Sheiner, L B",
  journal = "Am. Heart J.",
  volume  =  94,
  number  =  4,
  pages   = "529--530",
  year    =  1977
}

@ARTICLE{Wheeler1976-vd,
  title   = "A general method for optimal drug dose computation",
  author  = "Wheeler, L A and Sheiner, L B",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  4,
  number  =  6,
  pages   = "487--497",
  year    =  1976
}

@ARTICLE{Galeazzi1976-ne,
  title   = "Relationship between the pharmacokinetics and pharmacodynamics of
             procainamide",
  author  = "Galeazzi, R L and Benet, L Z and Sheiner, L B",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  20,
  number  =  3,
  pages   = "278--289",
  year    =  1976
}

@ARTICLE{Galeazzi1976-dt,
  title   = "The renal elimination of procainamide",
  author  = "Galeazzi, R L and Sheiner, L B and Lockwood, T and Benet, L Z",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  19,
  number  =  1,
  pages   = "55--62",
  year    =  1976
}

@ARTICLE{Sheiner1975-dp,
  title   = "Improved computer-assisted digoxin therapy. A method using
             feedback of measured serum digoxin concentrations",
  author  = "Sheiner, L B and Halkin, H and Peck, C and Rosenberg, B and
             Melmon, K L",
  journal = "Ann. Intern. Med.",
  volume  =  82,
  number  =  5,
  pages   = "619--627",
  year    =  1975
}

@ARTICLE{Halkin1975-nr,
  title   = "Determinants of the renal clearance of digoxin",
  author  = "Halkin, H and Sheiner, L B and Peck, C C and Melmon, K L",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  17,
  number  =  4,
  pages   = "385--394",
  year    =  1975
}

@ARTICLE{Sheiner1974-tw,
  title   = "Instructional goals for physicians in the use of blood level
             data--and the contribution of computers",
  author  = "Sheiner, L B and Melmon, K L and Rosenberg, B",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  16,
  number  =  1,
  pages   = "260--271",
  year    =  1974
}

@ARTICLE{Sheiner1974-lh,
  title   = "Differences in serum digoxin concentrations between outpatients
             and inpatients: an effect of compliance?",
  author  = "Sheiner, L B and Rosenberg, B and Marathe, V V and Peck, C",
  journal = "Clin. Pharmacol. Ther.",
  volume  =  15,
  number  =  3,
  pages   = "239--246",
  year    =  1974
}

@ARTICLE{Sheiner1974-gs,
  title   = "The use of serum concentrations of digitalis for quantitative
             therapeutic decisions",
  author  = "Sheiner, L B",
  journal = "Cardiovasc. Clin.",
  volume  =  6,
  number  =  2,
  pages   = "141--151",
  year    =  1974
}

@ARTICLE{Sanchez1973-qa,
  title   = "Pharmacokinetics of digoxin: interpreting bioavailability",
  author  = "Sanchez, N and Sheiner, L B and Halkin, H and Melmon, K L",
  journal = "Br. Med. J.",
  volume  =  4,
  number  =  5885,
  pages   = "132--134",
  year    =  1973
}

@ARTICLE{Peck1973-ns,
  title   = "Computer-assisted digoxin therapy",
  author  = "Peck, C C and Sheiner, L B and Martin, C M and Combs, D T and
             Melmon, K L",
  journal = "N. Engl. J. Med.",
  volume  =  289,
  number  =  9,
  pages   = "441--446",
  year    =  1973
}

@ARTICLE{Sheiner1972-cm,
  title   = "Modelling of individual pharmacokinetics for computer-aided drug
             dosage",
  author  = "Sheiner, L B and Rosenberg, B and Melmon, K L",
  journal = "Comput. Biomed. Res.",
  volume  =  5,
  number  =  5,
  pages   = "411--459",
  year    =  1972
}

@ARTICLE{Sheiner1969-pb,
  title   = "Computer-aided long-term anticoagulation therapy",
  author  = "Sheiner, L B",
  journal = "Comput. Biomed. Res.",
  volume  =  2,
  number  =  6,
  pages   = "507--518",
  year    =  1969
}

@ARTICLE{Molinaro1968-pj,
  title   = "Effect of chemical modification of dihydrouridine in yeast
             transfer ribonucleic acid on amino acid acceptor activity and
             ribosomal binding",
  author  = "Molinaro, M and Sheiner, L B and Neelon, F A and Cantoni, G L",
  journal = "J. Biol. Chem.",
  volume  =  243,
  number  =  6,
  pages   = "1277--1282",
  year    =  1968
}

@ARTICLE{Neelon1967-gm,
  title   = "Oligonucleotides produced by digestion of bakers' yeast serine
             transfer ribonucleic acid with specific nucleases",
  author  = "Neelon, F A and Molinaro, M and Ishikura, H and Sheiner, L B and
             Cantoni, G L",
  journal = "J. Biol. Chem.",
  volume  =  242,
  number  =  19,
  pages   = "4515--4522",
  year    =  1967
}

@ARTICLE{Sheiner1966-of,
  title   = "Coupled pacing and coupled pacing with concealed conduction.
             Report of a case describing a new observation",
  author  = "Sheiner, L B and Stock, R J",
  journal = "Circulation",
  volume  =  34,
  number  =  5,
  pages   = "759--766",
  year    =  1966
}

@ARTICLE{Suematsu2001-iq,
  title   = "Population-based investigation of relative clearance of digoxin in
             Japanese neonates and infants by multiple-trough screen analysis",
  author  = "Suematsu, F and Yukawa, E and Yukawa, M and Minemoto, M and Ohdo,
             S and Higuchi, S and Goto, Y",
  journal = "Eur. J. Clin. Pharmacol.",
  volume  =  57,
  number  =  1,
  pages   = "19--24",
  year    =  2001
}

@ARTICLE{Falcao2001-cl,
  title   = "Population Kinetics of Tobramycin in Neonates",
  author  = "Falcao, A C and Buelga, D S and Mendez, M E and Garcia, M J and
             Pardo, M",
  journal = "Ther. Drug Monit.",
  volume  =  23,
  number  =  3,
  pages   = "202--208",
  year    =  2001
}

@ARTICLE{Yates2001-uc,
  title   = "Time-variant increase in methylprednisolone clearance in patients
             with acute respiratory distress syndrome: a population
             pharmacokinetic study",
  author  = "Yates, C R and Vysokanov, A and Mukherjee, A and Ludden, T M and
             Tolley, E and Meduri, G U and Dalton, J T",
  journal = "J. Clin. Pharmacol.",
  volume  =  41,
  number  =  4,
  pages   = "415--424",
  year    =  2001
}

@ARTICLE{Breilh2001-zr,
  title   = "Pharmacokinetic population study to describe cefepime lung
             concentrations",
  author  = "Breilh, D and Saux, M C and Delaisement, C and Fratta, A and
             Ducint, D and Velly, J F and Couraud, L",
  journal = "Pulm. Pharmacol. Ther.",
  volume  =  14,
  number  =  2,
  pages   = "69--74",
  year    =  2001
}

@ARTICLE{Williams2001-ns,
  title   = "Dichloroacetate: population pharmacokinetics with a
             pharmacodynamic sequential link model",
  author  = "Williams, P J and Lane, J R and Turkel, C C and Capparelli, E V
             and Dziewanowska, Z and Fox, A W",
  journal = "J. Clin. Pharmacol.",
  volume  =  41,
  number  =  3,
  pages   = "259--267",
  year    =  2001
}

@ARTICLE{Reith2001-oq,
  title   = "Population pharmacokinetic modeling of steady state carbamazepine
             clearance in children, adolescents, and adults",
  author  = "Reith, D M and Hooper, W D and Parke, J and Charles, B",
  journal = "J. Pharmacokinet. Biopharm.",
  volume  =  28,
  number  =  1,
  pages   = "79--92",
  year    =  2001
}

@ARTICLE{Garcia_Sanchez2001-xp,
  title   = "Covariate effects on the apparent clearance of tacrolimus in
             paediatric liver transplant patients undergoing conversion therapy",
  author  = "Garcia Sanchez, M J and Manzanares, C and Santos-Buelga, D and
             Blazquez, A and Manzanares, J and Urruzuno, P and Medina, E",
  journal = "Clin. Pharmacokinet.",
  volume  =  40,
  number  =  1,
  pages   = "63--71",
  year    =  2001
}

@ARTICLE{Drover2000-nt,
  title   = "Pharmacokinetics, pharmacodynamics, and relative
             pharmacokinetic/pharmacodynamic profiles of zaleplon and zolpidem",
  author  = "Drover, D and Lemmens, H and Naidu, S and Cevallos, W and Darwish,
             M and Stanski, D",
  journal = "Clin. Ther.",
  volume  =  22,
  number  =  12,
  pages   = "1443--1461",
  year    =  2000
}

@ARTICLE{Wright2001-py,
  title   = "Estimation of glomerular filtration rate in cancer patients",
  author  = "Wright, J G and Boddy, A V and Highley, M and Fenwick, J and
             McGill, A and Calvert, A H",
  journal = "Br. J. Cancer",
  volume  =  84,
  number  =  4,
  pages   = "452--459",
  year    =  2001
}

@ARTICLE{Huitema2001-zr,
  title   = "Population pharmacokinetics of {thioTEPA} and its active
             metabolite {TEPA} in patients undergoing high-dose chemotherapy",
  author  = "Huitema, A D and Mathot, R A and Tibben, M M and Schellens, J H
             and Rodenhuis, S and Beijnen, J H",
  journal = "Br. J. Clin. Pharmacol.",
  volume  =  51,
  number  =  1,
  pages   = "61--70",
  year    =  2001
}

@ARTICLE{Parker2001-jn,
  title   = "Pharmacokinetic-pharmacodynamic modelling in the early development
             phase of anti-psychotics: a comparison of the effects of
             clozapine, {S} 16924 and {S} 18327 in the {EEG} model in rats",
  author  = "Parker, T J and Della Pasqua, O E and Loizillon, E and
             Chezaubernard, C and Jochemsen, R and Danhof, M",
  journal = "Br. J. Pharmacol.",
  volume  =  132,
  number  =  1,
  pages   = "151--158",
  year    =  2001
}

@ARTICLE{Kimura2001-bl,
  title   = "Population pharmacokinetics of panipenem in neonates and
             retrospective evaluation of dosage",
  author  = "Kimura, T and Kokubun, H and Nowatari, M and Matsuura, N and
             Sunakawa, K and Kubo, H",
  journal = "J. Antimicrob. Chemother.",
  volume  =  47,
  number  =  1,
  pages   = "51--59",
  year    =  2001
}

@ARTICLE{Xie2000-qv,
  title   = "Modelling of the blood-brain barrier transport of morphine-3-
             glucuronide studied using microdialysis in the rat: involvement of
             probenecid-sensitive transport",
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  journal = "Br. J. Pharmacol.",
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}

@ARTICLE{Jonsson2000-sx,
  title   = "Determination of drug effect on tumour cells, host animal toxicity
             and drug pharmacokinetics in a hollow-fibre model in rats",
  author  = "Jonsson, E and Friberg, L E and Karlsson, M O and Hassan, S B and
             Freijs, A and Hansen, K and Larsson, R",
  journal = "Cancer Chemother. Pharmacol.",
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  number  =  6,
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  year    =  2000
}

@ARTICLE{Sam2000-zb,
  title   = "Population pharmacokinetics of tacrolimus in Asian paediatric
             liver transplant patients",
  author  = "Sam, W J and Aw, M and Quak, S H and Lim, S M and Charles, B G and
             Chan, S Y and Ho, P C",
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}

@ARTICLE{Yukawa2000-hr,
  title   = "Epidemiologic investigation of the relative clearance of
             haloperidol by mixed-effect modeling using routine clinical
             pharmacokinetic data in Japanese patients",
  author  = "Yukawa, E and Hokazono, T and Funakoshi, A and Yukawa, M and Ohdo,
             S and Higuchi, S and Ichimaru, R and Makit, T and Matsunaga, K and
             Anai, M and Goto, Y",
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}

@ARTICLE{Parke2000-hn,
  title   = "Factors affecting oral cyclosporin disposition after heart
             transplantation: bootstrap validation of a population
             pharmacokinetic model",
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@ARTICLE{Friberg2000-vk,
  title   = "Semiphysiological model for the time course of leukocytes after
             varying schedules of 5-fluorouracil in rats",
  author  = "Friberg, L E and Freijs, A and Sandstrom, M and Karlsson, M O",
  journal = "J. Pharmacol. Exp. Ther.",
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@ARTICLE{Ingwersen2000-jn,
  title   = "Population pharmacokinetics of tiagabine in epileptic patients on
             monotherapy",
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             Aarons, L",
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}

@ARTICLE{Wrishko2000-lb,
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             patients",
  author  = "Wrishko, R E and Levine, M and Khoo, D and Abbott, P and Hamilton,
             D",
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@ARTICLE{Farenc2000-vm,
  title   = "Pk-fit: a pharmacokinetic/pharmacodynamic and statistical data
             analysis software",
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@ARTICLE{Ouellet2000-ea,
  title   = "Population pharmacokinetics of pemetrexed disodium ({ALIMTA}) in
             patients with cancer",
  author  = "Ouellet, D and Periclou, A P and Johnson, R D and Woodworth, J R
             and Lalonde, R L",
  journal = "Cancer Chemother. Pharmacol.",
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}

@ARTICLE{Freyer2000-li,
  title   = "Population pharmacokinetics of doxorubicin, etoposide and
             ifosfamide in small cell lung cancer patients: results of a
             multicentre study",
  author  = "Freyer, G and Tranchand, B and Ligneau, B and Ardiet, C and
             Souquet, P J and Court, Fortune and Riou, R and Rebattu, P and
             Boissel, J P and Trillet-Lenoir, V and Girard, P",
  journal = "Br. J. Clin. Pharmacol.",
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}

@ARTICLE{Gidal2000-er,
  title   = "Lack of an effect of valproate concentration on lamotrigine
             pharmacokinetics in developmentally disabled patients with
             epilepsy",
  author  = "Gidal, B E and Anderson, G D and Rutecki, P R and Shaw, R and
             Lanning, A",
  journal = "Epilepsy Res.",
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}

@ARTICLE{Lill2000-pf,
  title   = "Cyclosporine-drug interactions and the influence of patient age",
  author  = "Lill, J and Bauer, L A and Horn, J R and Hansten, P D",
  journal = "Am. J. Health. Syst. Pharm.",
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}

@ARTICLE{Simonsen2000-pj,
  title   = "Haematological toxicity following different dosing schedules of 5-
             fluorouracil and epirubicin in rats",
  author  = "Simonsen, L E and Wahlby, U and Sandstrom, M and Freijs, A and
             Karlsson, M O",
  journal = "Anticancer Res.",
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}

@ARTICLE{Xuan2000-cu,
  title   = "Population pharmacokinetics of tobramycin in hospitalized patients
             receiving once-daily dosing regimen",
  author  = "Xuan, D and Lu, J F and Nicolau, D P and Nightingale, C H",
  journal = "Int. J. Antimicrob. Agents",
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  pages   = "185--191",
  year    =  2000
}

@ARTICLE{Gauvin2000-ou,
  title   = "Bayesian estimate of vinorelbine pharmacokinetic parameters in
             elderly patients with advanced metastatic cancer",
  author  = "Gauvin, A and Pinguet, F and Culine, S and Astre, C and Gomeni, R
             and Bressolle, F",
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}

@ARTICLE{Pollak2000-tc,
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  author  = "Pollak, P T and Bouillon, T and Shafer, S L",
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}

@ARTICLE{Jorga2000-rp,
  title   = "Population pharmacokinetics of levodopa in patients with
             Parkinson's disease treated with tolcapone",
  author  = "Jorga, K and Banken, L and Fotteler, B and Snell, P and Steimer, J
             L",
  journal = "Clin. Pharmacol. Ther.",
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@ARTICLE{Kimura2000-hh,
  title   = "[Pharmacokinetics of panipenem in neonates and dosage
             recommendation]",
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  journal = "Jpn. J. Antibiot.",
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}

@ARTICLE{Jackson2000-ji,
  title   = "A population pharmacokinetic analysis of nelfinavir mesylate in
             human immunodeficiency virus-infected patients enrolled in a phase
             {III} clinical trial",
  author  = "Jackson, K A and Rosenbaum, S E and Kerr, B M and Pithavala, Y K
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  journal = "Antimicrob. Agents Chemother.",
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@ARTICLE{Valodia2000-la,
  title   = "Validation of population pharmacokinetic parameters of phenytoin
             using the parallel {Michaelis-Menten} and first-order elimination
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@ARTICLE{Kerbusch2000-fc,
  title   = "Evaluation of the autoinduction of ifosfamide metabolism by a
             population pharmacokinetic approach using {NONMEM}",
  author  = "Kerbusch, T and Huitema, A D and Ouwerkerk, J and Keizer, H J and
             Mathot, R A and Schellens, J H and Beijnen, J H",
  journal = "Br. J. Clin. Pharmacol.",
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@ARTICLE{Duffull2000-ce,
  title   = "A pharmacokinetic simulation model for ivabradine in healthy
             volunteers",
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@ARTICLE{Duffull2000-uw,
  title   = "Development of a sequential linked pharmacokinetic and
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             volunteers",
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@ARTICLE{Dempsey2000-lh,
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@ARTICLE{Furuya2000-ms,
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             selective nonpeptide platelet glycoprotein {IIb/IIIa} receptor
             antagonist in normal healthy subjects",
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@ARTICLE{Mamiya2000-vg,
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             in Japanese patients with epilepsy: analysis by population
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  author  = "Mamiya, K and Hadama, A and Yukawa, E and Ieiri, I and Otsubo, K
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@ARTICLE{Bouzom2000-iz,
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@ARTICLE{Chen2000-ao,
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@ARTICLE{Schuttler2000-vh,
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}

@ARTICLE{Maier1999-gd,
  title   = "Characterization of the highly variable bioavailability of
             tiludronate in normal volunteers using population pharmacokinetic
             methodologies",
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@ARTICLE{Zhou2000-sl,
  title   = "Population pharmacokinetics/toxicodynamics ({PK/TD}) relationship
             of {SAM486A} in phase {I} studies in patients with advanced
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@ARTICLE{Peng2000-jw,
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@ARTICLE{MacGregor2000-pj,
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@ARTICLE{Gwilt2000-ic,
  title   = "Pharmacokinetics of levamisole in cancer patients treated with 5-
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  author  = "Gwilt, P and Tempero, M and Kremer, A and Connolly, M and Ding, C",
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@ARTICLE{Schuitmaker1999-eg,
  title   = "Pharmacokinetics of paracetamol in adults after cardiac surgery",
  author  = "Schuitmaker, M and Anderson, B J and Holford, N H and Woollard, G
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@ARTICLE{Vermes2000-gz,
  title   = "Population pharmacokinetics of flucytosine: comparison and
             validation of three models using {STS}, {NPEM}, and {NONMEM}",
  author  = "Vermes, A and Math t, R A and Van, der Sijs I and Dankert, J and
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@ARTICLE{Jorga2000-lm,
  title   = "Population pharmacokinetics of tolcapone in parkinsonian patients
             in dose finding studies",
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@ARTICLE{Du_Preez1999-gb,
  title   = "The pharmacokinetics of theophylline in premature neonates during
             the first few days after birth",
  author  = "du Preez, M J and Botha, J H and McFadyen, M L and Holford, N H",
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@ARTICLE{Frame1999-up,
  title   = "Population pharmacokinetics of continuous infusion ceftazidime",
  author  = "Frame, B C and Facca, B F and Nicolau, D P and Triesenberg, S N",
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@ARTICLE{Blanco-Serrano1999-dv,
  title   = "Population estimation of valproic acid clearance in adult patients
             using routine clinical pharmacokinetic data",
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             Garcia-Sanchez, M J and Serrano, J and Dominguez-Gil, A",
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@ARTICLE{Preechagoon1999-jh,
  title   = "Population pharmacokinetics of enterally administered cisapride in
             young infants with gastro-oesophageal reflux disease",
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@ARTICLE{Hassan1999-fm,
  title   = "A mechanism-based pharmacokinetic-enzyme model for
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  author  = "Hassan, M and Svensson, U S and Ljungman, P and Bjorkstrand, B and
             Olsson, H and Bielenstein, M and Abdel-Rehim, M and Nilsson, C and
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@ARTICLE{Moore1999-es,
  title   = "Population pharmacokinetics of lamivudine in adult human
             immunodeficiency virus-infected patients enrolled in two phase
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  author  = "Moore, K H and Yuen, G J and Hussey, E K and Pakes, G E and Eron,
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@ARTICLE{Buchwalder-Csajka1999-cw,
  title   = "Evaluation of the angiotensin challenge methodology for assessing
             the pharmacodynamic profile of antihypertensive drugs acting on
             the renin- angiotensin system",
  author  = "Buchwalder-Csajka, C and Buclin, T and Brunner, H R and Biollaz, J",
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@ARTICLE{Sandstrom1999-zh,
  title   = "The pharmacokinetics of epirubicin and docetaxel in combination in
             rats",
  author  = "Sandstrom, M and Simonsen, L E and Freijs, A and Karlsson, M O",
  journal = "Cancer Chemother. Pharmacol.",
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@ARTICLE{Grimsley1999-cx,
  title   = "Pharmacokinetics and dose requirements of vancomycin in neonates",
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@ARTICLE{Romano1999-fp,
  title   = "Population pharmacokinetics of amikacin in patients with
             haematological malignancies",
  author  = "Romano, S and Fdez de Gatta, M M and Calvo, M V and Caballero, D
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@ARTICLE{Zhou1999-nr,
  title   = "Effect of meal timing not critical for the pharmacokinetics of
             tegaserod ({HTF} 919)",
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@ARTICLE{Bressolle1999-wo,
  title   = "Circadian rhythm of 5-fluorouracil population pharmacokinetics in
             patients with metastatic colorectal cancer",
  author  = "Bressolle, F and Joulia, J M and Pinguet, F and Ychou, M and
             Astre, C and Duffour, J and Gomeni, R",
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@ARTICLE{Rehberg1999-od,
  title   = "Comparative pharmacodynamic modeling of the
             electroencephalography- slowing effect of isoflurane, sevoflurane,
             and desflurane",
  author  = "Rehberg, B and Bouillon, T and Zinserling, J and Hoeft, A",
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@ARTICLE{Mirochnick1999-ui,
  title   = "Pharmacokinetics of zidovudine in infants: a population analysis
             across studies",
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@ARTICLE{Bouillon1999-uc,
  title   = "Pharmacokinetic-pharmacodynamic modeling of the respiratory
             depressant effect of alfentanil",
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@ARTICLE{Joubert1999-nf,
  title   = "A population approach to the forecasting of amikacin plasma and
             urinary levels using a prescribed dosage regimen",
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@ARTICLE{Brynne1999-wy,
  title   = "Mechanism-based modeling of rebound tachycardia after chronic l-
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@ARTICLE{Boni1999-rx,
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@ARTICLE{Pfister1999-qm,
  title   = "Pharmacokinetics and haemodynamics of candesartan cilexetil in
             hypertensive patients on regular haemodialysis",
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@ARTICLE{Yukawa1999-he,
  title   = "Population-based investigations of drug relative clearance using
             nonlinear mixed-effect modelling from information generated during
             the routine clinical care of patients",
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@ARTICLE{Campbell1999-wd,
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@ARTICLE{Wallenstein1999-pb,
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@ARTICLE{Serrano1999-xs,
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@ARTICLE{Chatelut1999-hk,
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@ARTICLE{Parke1999-tw,
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@ARTICLE{Laporte1999-rg,
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@ARTICLE{Flores-Murrieta1998-zu,
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@ARTICLE{Sakurai1999-ak,
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@ARTICLE{Grasela1999-jb,
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@ARTICLE{Jonsson1999-vt,
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@ARTICLE{Bressolle1998-to,
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@ARTICLE{Gisleskog1999-kp,
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@ARTICLE{Jonsson1999-uv,
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@ARTICLE{Valodia1999-pz,
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@ARTICLE{Lee1999-ia,
  title   = "Population pharmacokinetic modeling in very premature infants
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@ARTICLE{Meineke1998-cy,
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@ARTICLE{Perdaems1998-aq,
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@ARTICLE{Welker1998-ed,
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@ARTICLE{Gisleskog1998-np,
  title   = "A model for the turnover of dihydrotestosterone in the presence of
             the irreversible 5 alpha-reductase inhibitors {GI198745} and
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@ARTICLE{Mamiya1998-sa,
  title   = "The effects of genetic polymorphisms of {CYP2C9} and {CYP2C19} on
             phenytoin metabolism in Japanese adult patients with epilepsy:
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             pharmacokinetics",
  author  = "Mamiya, K and Ieiri, I and Shimamoto, J and Yukawa, E and Imai, J
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@ARTICLE{Somma1998-pq,
  title   = "Population pharmacodynamics of midazolam administered by target
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@ARTICLE{Zomorodi1998-vt,
  title   = "Population pharmacokinetics of midazolam administered by target
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@ARTICLE{Yasuhara1998-xz,
  title   = "Population pharmacokinetics of vancomycin in Japanese pediatric
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@ARTICLE{Lee1998-df,
  title   = "Estimation of mean relative bioavailability of cyclosporine
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@ARTICLE{Nagai1998-ug,
  title   = "Population pharmacokinetics and pharmacodynamics of cisplatin in
             patients with cancer: analysis with the {NONMEM} program",
  author  = "Nagai, N and Ogata, H and Wada, Y and Tsujino, D and Someya, K and
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@ARTICLE{Shafer1998-ac,
  title   = "Cerebrospinal fluid pharmacokinetics and pharmacodynamics of
             intrathecal neostigmine methylsulfate in humans",
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@ARTICLE{Gwilt1998-nx,
  title   = "Pharmacokinetics of 2-oxothiazolidine-4-carboxylate, a cysteine
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@ARTICLE{Godfrey1998-mm,
  title   = "The population pharmacokinetics of long-term methotrexate in
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@ARTICLE{Romano1998-tj,
  title   = "Influence of diagnostic and treatment factors in the population
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@ARTICLE{Drover1998-fl,
  title   = "Population pharmacodynamics and pharmacokinetics of remifentanil
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@ARTICLE{Anderson1998-kl,
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@ARTICLE{Rosario1998-dv,
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@ARTICLE{Jonsson1998-ev,
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@ARTICLE{Smith1998-ou,
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@ARTICLE{Martin1998-ds,
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@ARTICLE{Ragueneau1998-cs,
  title   = "Pharmacokinetic-pharmacodynamic modeling of the effects of
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@ARTICLE{Frame1998-om,
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@ARTICLE{Gray1998-el,
  title   = "A model for the determination of carbamazepine clearance in
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@ARTICLE{Hayashi1998-gg,
  title   = "Pharmacokinetic analysis of subcutaneous erythropoietin
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@ARTICLE{Gatti1998-sl,
  title   = "Population pharmacokinetics of rifabutin in human immunodeficiency
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@ARTICLE{Piotrovsky1998-wp,
  title   = "Effects of demographic variables on vorozole pharmacokinetics in
             healthy volunteers and in breast cancer patients",
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@ARTICLE{Welker1998-qq,
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@ARTICLE{Facca1998-iq,
  title   = "Population pharmacokinetics of ceftizoxime administered by
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@ARTICLE{Parke1998-bx,
  title   = "{NONMEM} population pharmacokinetic modeling of orally
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             heart transplantation",
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@ARTICLE{Etienne1998-zo,
  title   = "Co-variables influencing 5-fluorouracil clearance during
             continuous venous infusion. A {NONMEM} analysis",
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@ARTICLE{Ette1998-mj,
  title   = "Balanced designs in longitudinal population pharmacokinetic
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@ARTICLE{Yukawa1998-xb,
  title   = "Detection of a drug-drug interaction on population-based
             phenobarbitone clearance using nonlinear mixed-effects modeling",
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@ARTICLE{Laveille1998-si,
  title   = "Application of population pharmacokinetics to the phase {II}
             development of an anti-Alzheimer's disease compound, {S12024}",
  author  = "Laveille, C and Lachaud-Pettiti, V and Neuman, E and Jochemsen, R",
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@ARTICLE{Wright1998-az,
  title   = "Can bioavailability of low-variance drugs be estimated with an
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@ARTICLE{Sidhu1998-sa,
  title   = "Artemisinin population pharmacokinetics in children and adults
             with uncomplicated falciparum malaria",
  author  = "Sidhu, J S and Ashton, M and Huong, N V and Hai, T N and Karlsson,
             M O and Sy, N D and Jonsson, E N and Cong, L D",
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@ARTICLE{Idkaidek1998-hu,
  title   = "Determination of the population pharmacokinetic parameters of
             sustained- release and enteric-coated oral formulations, and the
             suppository formulation of diclofenac sodium by simultaneous data
             fitting using {NONMEM}",
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@ARTICLE{Yasuhara1998-la,
  title   = "Population pharmacokinetics of vancomycin in Japanese adult
             patients",
  author  = "Yasuhara, M and Iga, T and Zenda, H and Okumura, K and Oguma, T
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@ARTICLE{Marino1998-vp,
  title   = "Population pharmacokinetics and pharmacodynamics of pyridostigmine
             bromide for prophylaxis against nerve agents in humans",
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@ARTICLE{Botha1998-ji,
  title   = "Determination of population pharmacokinetic parameters for
             amikacin in neonates using mixed-effect models",
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@ARTICLE{Yukawa1997-wh,
  title   = "Population-based investigation of valproic acid relative clearance
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@ARTICLE{Schaedeli1998-pg,
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@ARTICLE{Nguyen1998-ok,
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  author  = "Nguyen, L and Chatelut, E and Chevreau, C and Tranchand, B and
             Lochon, I and Bachaud, J M and Pujol, A and Houin, G and Bugat, R
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@ARTICLE{Bruno1997-yf,
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@ARTICLE{Benezet1997-oq,
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@ARTICLE{Ette1997-ij,
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@ARTICLE{Hussein1997-fr,
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@ARTICLE{Delgado_Iribarnegaray1997-ci,
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@ARTICLE{Hossain1997-eh,
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@ARTICLE{Yukawa1997-rd,
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@ARTICLE{Schmith1997-fg,
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@ARTICLE{McFadyen1997-kx,
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@ARTICLE{Looby1997-ix,
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@ARTICLE{Yukawa1996-re,
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@ARTICLE{Boyd1996-he,
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@ARTICLE{Carlton1996-bb,
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@ARTICLE{Schaefer1996-lm,
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@ARTICLE{Albrecht1995-mm,
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@ARTICLE{Brier1995-yo,
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             relationships in patients with essential hypertension",
  author  = "Wade

license: MIT

license_type: permissive

branch_name: refs/heads/master

extension: bib