text:
{10.1016/j.neuroimage.2004.08.055},
pii = {S1053-8119(04)00587-7},
pmid = {15588616},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Friston-2005-Neuroimage_Mixed-effects%20and%20fM.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2336},
rating = {0}
}

@article{Berrar:2003p3267,
author = {Daniel P Berrar and C Stephen Downes and Werner Dubitzky},
journal = {Pac Symp Biocomput},
title = {Multiclass cancer classification using gene expression profiling and probabilistic neural networks},
abstract = {Gene expression profiling by microarray technology has been successfully applied to classification and diagnostic prediction of cancers. Various machine learning and data mining methods are currently used for classifying gene expression data. However, these methods have not been developed to address the specific requirements of gene microarray analysis. First, microarray data is characterized by a high-dimensional feature space often exceeding the sample space dimensionality by a factor of 100 or more. In addition, microarray data exhibit a high degree of noise. Most of the discussed methods do not adequately address the problem of dimensionality and noise. Furthermore, although machine learning and data mining methods are based on statistics, most such techniques do not address the biologist's requirement for sound mathematical confidence measures. Finally, most machine learning and data mining classification methods fail to incorporate misclassification costs, i.e. they are indifferent to the costs associated with false positive and false negative classifications. In this paper, we present a probabilistic neural network (PNN) model that addresses all these issues. The PNN model provides sound statistical confidences for its decisions, and it is able to model asymmetrical misclassification costs. Furthermore, we demonstrate the performance of the PNN for multiclass gene expression data sets. Here, we compare the performance of the PNN with two machine learning methods, a decision tree and a neural network. To assess and evaluate the performance of the classifiers, we use a lift-based scoring system that allows a fair comparison of different models. The PNN clearly outperformed the other models. The results demonstrate the successful application of the PNN model for multiclass cancer classification.},
affiliation = {School of Biomedical Sciences, University of Ulster at Coleraine, BT521SA, Northern Ireland. dp.berrar@ulster.ac.uk},
pages = {5--16},
year = {2003},
month = {Jan},
language = {eng},
keywords = {Oligonucleotide Array Sequence Analysis, Databases: Genetic, Humans, Neoplasms, Bayes Theorem, Tumor Cells: Cultured, Gene Expression Profiling, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia: Myeloid: Acute, Neural Networks (Computer), Models: Statistical, Female, Male, Artificial Intelligence},
date-added = {2010-01-14 21:05:30 +0100},
date-modified = {2010-07-29 19:42:21 +0200},
pmid = {12603013},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3267},
rating = {0}
}

@article{Hugot:2001p5607,
author = {J P Hugot and M Chamaillard and H Zouali and S Lesage and J P C{\'e}zard and J Belaiche and S Almer and C Tysk and C A O'Morain and M Gassull and V Binder and Y Finkel and A Cortot and R Modigliani and P Laurent-Puig and C Gower-Rousseau and J Macry and J F Colombel and M Sahbatou and G Thomas},
journal = {Nature},
title = {Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease},
abstract = {Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions of unknown aetiology. A susceptibility locus for Crohn's disease has been mapped to chromosome 16. Here we have used a positional-cloning strategy, based on linkage analysis followed by linkage disequilibrium mapping, to identify three independent associations for Crohn's disease: a frameshift variant and two missense variants of NOD2, encoding a member of the Apaf-1/Ced-4 superfamily of apoptosis regulators that is expressed in monocytes. These NOD2 variants alter the structure of either the leucine-rich repeat domain of the protein or the adjacent region. NOD2 activates nuclear factor NF-kB; this activating function is regulated by the carboxy-terminal leucine-rich repeat domain, which has an inhibitory role and also acts as an intracellular receptor for components of microbial pathogens. These observations suggest that the NOD2 gene product confers susceptibility to Crohn's disease by altering the recognition of these components and/or by over-activating NF-kB in monocytes, thus documenting a molecular model for the pathogenic mechanism of Crohn's disease that can now be further investigated.},
affiliation = {Fondation Jean Dausset CEPH, 27 rue J. Dodu 75010 Paris, France.},
number = {6837},
pages = {599--603},
volume = {411},
year = {2001},
month = {May},
language = {eng},
keywords = {Polymorphism: Single Nucleotide, Alleles, Linkage (Genetics), Gene Frequency, Signal Transduction, Repetitive Sequences: Amino Acid, Genetic Variation, Genetic Predisposition to Disease, Leucine, Nod2 Signaling Adaptor Protein, Proteins, Intracellular Signaling Peptides and Proteins, Cloning: Molecular, Crohn Disease, Humans, Chromosomes: Human: Pair 16, Carrier Proteins, Genotype, Colitis: Ulcerative, NF-kappa B},
date-added = {2010-02-12 15:46:09 +0100},
date-modified = {2010-07-29 19:40:35 +0200},
doi = {10.1038/35079107},
pii = {35079107},
pmid = {11385576},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hugot-2001-Nature_Association%20of%20NOD2.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5607},
rating = {0}
}

@article{Binder:2009p4131,
author = {Elisabeth B Binder and D Jeffrey Newport and Elizabeth B Zach and Alicia K Smith and Todd C Deveau and Lori L Altshuler and Lee S Cohen and Zachary N Stowe and Joseph F Cubells},
journal = {J Psychiatr Res},
title = {A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort},
abstract = {BACKGROUD: Peripartum major depressive disorder (MDD) is a prevalent psychiatric disorder with potential detrimental consequences for both mother and child. Despite its enormous health care relevance, data regarding genetic predictors of peripartum depression are sparse. The aim of this study was to investigate associations of the serotonin-transporter linked polymorphic region (5-HTTLPR) genotype with peripartum MDD in an at-risk population. METHODS: Two hundred and seventy four women with a prior history of MDD were genotyped for 5-HTTLPR and serially evaluated in late pregnancy (gestational weeks 31-40), early post-partum (week 1-8) and late post-partum (week 9-24) for diagnosis of a current major depressive episode (MDE) and depressive symptom severity. RESULTS: 5-HTTLPR S-allele carrier status predicted the occurrence of a MDE in the early post-partum period only (OR=5.13, p=0.017). This association persisted despite continued antidepressant treatment. CONCLUSIONS: The 5-HTTLPR genotype may be a clinically relevant predictor of early post-partum depression in an at-risk population. OBJECTIVE: Peripartum major depressive disorder is a prevalent psychiatric disorder with potential detrimental consequences for both mother and child. Despite its enormous health care relevance, data regarding genetic predictors of peripartum depression are sparse. The aim of this study was to investigate associations of the serotonin-transporter linked polymorphic region (5-HTTLPR) genotype with peripartum MDD in an at-risk population.},
affiliation = {Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA; Emory University School of Medicine, Department of Human Genetics, Atlanta, GA, USA; Max Planck Institute of Psychiatry, Munich, Germany.},
pages = {},
year = {2009},
month = {Dec},
language = {ENG},
date-added = {2010-01-20 21:58:02 +0100},
date-modified = {2010-07-29 19:35:54 +0200},
doi = {10.1016/j.jpsychires.2009.12.001},
pii = {S0022-3956(09)00273-8},
pmid = {20045118},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4131},
rating = {0}
}

@article{Golder:2010p12084,
author = {Su Golder and Yoon K Loke and Martin Bland},
journal = {Journal of Clinical Epidemiology},
title = {Unpublished data can be of value in systematic reviews of adverse effects: methodological overview},
abstract = {OBJECTIVE: To assess the impact of including unpublished data on adverse effects in systematic reviews. STUDY DESIGN AND SETTING: We carried out a systematic review of methodological evaluations that compared the quantitative reporting of adverse effects data between published and unpublished sources, in particular, the frequency, rate, or risk of reported adverse effects. Included studies were sought from 10 databases as well as by checking references, handsearching, searching citations, and contacting experts. RESULTS: We identified 6,218 potential articles yielding 10 relevant methodological evaluations. One evaluation found that adverse effects were reported more often in unpublished trials. For anecdotal case reports, two evaluations found a higher frequency of unpublished cases, whereas one study identified a greater number of published cases. Another evaluation indicated that differences in frequency of published and unpublished case reports were topic dependent. A comparison of relative risk estimates from five studies suggested no major systematic variation in risk estimates from published and unpublished studies. CONCLUSION: Inclusion of unpublished studies can provide additional adverse effects information and more precise risk estimates. However, there is insufficient evidence to indicate whether inclusion of unpublished studies has a major influence on the pooled risk estimates in meta-analyses of adverse effects.},
affiliation = {Centre for Reviews and Dissemination (CRD), University of York, York, YO10 5DD, UK; Department of Health Sciences, University of York, York, YO10 5DD, UK.},
pages = {},
year = {2010},
month = {May},
language = {ENG},
date-added = {2010-05-24 12:30:57 +0200},
date-modified = {2010-05-24 12:30:57 +0200},
doi = {10.1016/j.jclinepi.2010.02.009},
pii = {S0895-4356(10)00094-6},
pmid = {20457510},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Golder-2010-Journal%20of%20Clinical%20Epidemiology_Unpublished%20data%20can-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12084},
rating = {0}
}

@misc{Schumacher:1996,
author = {M Schumacher and R Rossner and W Vach},
journal = {Miscellaneous},
title = {Neural network and logistic regression. Part I},
year = {1996},
date-added = {2010-01-10 11:33:18 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Schumacher-1996-Miscellaneous_Neural%20network%20and%20l.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2060},
rating = {0}
}

@article{Robert:2010p13348,
author = {Christian P Robert},
journal = {arXiv},
title = {Bayesian computational methods},
abstract = { In this chapter, we will first present the most standard computational challenges met in Bayesian Statistics, focussing primarily on mixture estimation and on model choice issues, and then relate these problems with computational solutions. Of course, this chapter is only a terse introduction to the problems and solutions related to Bayesian computations. For more complete references, see Robert and Casella (2004, 2009), or Marin and Robert (2007), among others. We also restrain from providing an introduction to Bayesian Statistics per se and for comprehensive coverage, address the reader to Robert (2007), (again) among others. },
annote = {This is a revised version of a chapter written for the Handbook of
  Computational Statistics, edited by J. Gentle, W. Hardle and Y. Mori in 2003,
  in preparation for the second edition},
eprint = {1002.2702v1},
volume = {stat.CO},
year = {2010},
month = {Feb},
keywords = {stat.CO, stat.ME},
date-added = {2010-07-01 19:10:36 +0200},
date-modified = {2010-07-01 19:10:36 +0200},
pmid = {1002.2702v1},
URL = {http://arxiv.org/abs/1002.2702v1},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Robert-2010-arXiv_Bayesian%20computation.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13348},
rating = {0}
}

@article{Enzi:2009p12291,
author = {Bj{\"o}rn Enzi and Moritz de Greck and Ulrike Pr{\"o}sch and Claus Tempelmann and Georg Northoff},
journal = {PLoS ONE},
title = {Is our self nothing but reward? Neuronal overlap and distinction between reward and personal relevance and its relation to human personality},
abstract = {BACKGROUND: The attribution of personal relevance, i.e. relating internal and external stimuli to establish a sense of belonging, is a common phenomenon in daily life. Although previous research demonstrated a relationship between reward and personal relevance, their exact neuronal relationship including the impact of personality traits remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: Using functional magnetic resonance imaging, we applied an experimental paradigm that allowed us to explore the neural response evoked by reward and the attribution of personal relevance separately. We observed different brain regions previously reported to be active during reward and personal relevance, including the bilateral caudate nucleus and the pregenual anterior cingulate cortex (PACC). Additional analysis revealed activations in the right and left insula specific for the attribution of personal relevance. Furthermore, our results demonstrate a negative correlation between signal changes in both the PACC and the left anterior insula during the attribution of low personal relevance and the personality dimension novelty seeking. CONCLUSION/SIGNIFICANCE: While a set of subcortical and cortical regions including the PACC is commonly involved in reward and personal relevance, other regions like the bilateral anterior insula were recruited specifically during personal relevance. Based on our correlation between novelty seeking and signal changes in both regions during personal relevance, we assume that the neuronal response to personally relevant stimuli is dependent on the personality trait novelty seeking.},
affiliation = {Department of Psychiatry, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.},
number = {12},
pages = {e8429},
volume = {4},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Reward, Neurons, Adult, Middle Aged, Humans, Young Adult, Male, Temperament, Magnetic Resonance Imaging, Exploratory Behavior, Personality Inventory, Time Factors, Brain Mapping, Personality, Female},
date-added = {2010-06-09 20:14:28 +0200},
date-modified = {2010-06-09 20:14:31 +0200},
doi = {10.1371/journal.pone.0008429},
pmid = {20041155},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Enzi-2009-PLoS%20ONE_Is%20our%20self%20nothing.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12291},
rating = {3}
}

@article{Morisano:2009p3091,
author = {Dominique Morisano and Ingrid Bacher and Janet Audrain-McGovern and Tony P George},
journal = {Can J Psychiatry},
title = {Mechanisms underlying the comorbidity of tobacco use in mental health and addictive disorders},
abstract = {We discuss potential explanations for the high prevalence of tobacco use and tobacco dependence (TD) in people with mental health and addictive (MHA) disorders. The biopsychosocial basis for this comorbidity is presented, integrating evidence from epidemiologic and clinical studies. We also review evidence that suggests a shared vulnerability related to biological, genetic, and environmental factors may be the most parsimonious mechanism to explain the association between TD and MHA disorders. Finally, we review the examples of various MHA disorders that are associated with TD, and suggest avenues for new investigation that could aid in the development of rationale and more effective treatments for tobacco and MHA disorder comorbidities.},
affiliation = {Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario.},
number = {6},
pages = {356--67},
volume = {54},
year = {2009},
month = {Jun},
language = {eng},
keywords = {Brain, Humans, Neurotransmitter Agents, Cross-Sectional Studies, Smoking, Genetic Predisposition to Disease, Comorbidity, Substance-Related Disorders, Smoking Cessation, Diseases in Twins, Twin Studies as Topic, Receptors: Neurotransmitter, Risk Factors, Treatment Outcome, Nicotine, Mental Disorders},
date-added = {2010-01-14 19:55:58 +0100},
date-modified = {2010-01-14 19:55:58 +0100},
pmid = {19527556},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3091},
rating = {0}
}

@article{Verissimo:2009p14056,
author = {Ramiro Verissimo and Bob Bermond},
journal = {Acta Med Port},
title = {[Cross-cultural psychometric assessment of the Bermond-Vorst alexithymia questionnaire]},
abstract = {The alexithymia construct was introduced by Nemiah and Sifneos in the early 70s. It is a multifaceted personality construct that has been recognized associated with various conditions of health disorders. Nonetheless, despite the abundant literature, due to methodological weaknesses, a great share of the studies has been proved of questionable validity and reliability. In recent years a new self-report instrument has been developed, the Bermond-Vorst Alexithymia Questionnaire (BVAQ), meant to assess the alexithymia construct in a more comprehensive way than the more commonly used 20-item Toronto Alexithymia Scale (TAS-20). The aim was to investigate the cross-cultural psychometric properties of the Portuguese version of the BVAQ. In this study, carried out in a sample of university students (n = 369), we began testing the originally proposed 5-factor structure, by means of a factor analysis; just to proceed thereafter with the internal consistencies determination. Furthermore we investigated the stability, as well as its convergent validity with the Toronto Alexithymia Scale--20 items (TAS-20). Principal Components Analysis showed that internal structure of the 40 items acceptably fitted into the 5-factor solution. The mean total score differs about 0.6 SD from the original Dutch sample. Internal consistencies are also acceptably about the ones in the original sample: Cronbach's alpha = 0.82 for the global scale and a mean 0.77 for the subscales. Moreover the instrument is reliably stable; and the expected correlations between BVAQ and TAS-20 subscales support evidence of BVAQ's validity. The Portuguese version of the BVAQ is a highly promising new instrument to comprehensively assess alexithymia, and its use can therefore be recommended.},
affiliation = {Psicologia M{\'e}dica, Faculdade de Medicina da Universidade do Porto, Porto.},
number = {6},
pages = {767--72},
volume = {22},
year = {2009},
month = {Jan},
language = {por},
date-added = {2010-08-18 10:03:14 +0200},
date-modified = {2010-08-18 10:03:14 +0200},
pmid = {20350460},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14056},
rating = {0}
}

@article{Burnett:2009p4834,
author = {Stephanie Burnett and Sarah-Jayne Blakemore},
journal = {Eur J Neurosci},
title = {Functional connectivity during a social emotion task in adolescents and in adults},
abstract = {In this fMRI study we investigated functional connectivity between components of the mentalising system during a social emotion task, using psychophysiological interaction (PPI) analysis. Ten adults (22-32 years) and 18 adolescents (11-18 years) were scanned while thinking about scenarios in which a social or a basic emotion would be experienced. Unlike basic emotions (such as disgust and fear), social emotions (such as embarrassment and guilt) require the representation of another's mental states. In both adults and adolescents, an anterior rostral region of medial prefrontal cortex (arMPFC) involved in mentalising showed greater connectivity with the posterior superior temporal sulcus (pSTS) bordering on the temporo-parietal junction (TPJ) and with anterior temporal cortex (ATC) during social than during basic emotion. This result provides novel evidence that components of the mentalising system interact functionally during a social emotion task. Furthermore, functional connectivity differed between adolescence and adulthood. The adolescent group showed stronger connectivity between arMPFC and pSTS/TPJ during social relative to basic emotion than did the adult group, suggestive of developmental changes in functional integration within the mentalising system.},
affiliation = {Institute of Cognitive Neuroscience, University College London, London, UK. burstephanie@gmail.com},
number = {6},
pages = {1294--301},
volume = {29},
year = {2009},
month = {Mar},
language = {eng},
keywords = {Child, Image Processing: Computer-Assisted, Adolescent, Brain Mapping, Oxygen, Magnetic Resonance Imaging, Age Factors, Brain, Young Adult, Neuropsychological Tests, Female, Interpersonal Relations, Emotions, Adult, Humans, Psychophysics},
date-added = {2010-02-01 20:21:57 +0100},
date-modified = {2010-02-01 20:21:57 +0100},
doi = {10.1111/j.1460-9568.2009.06674.x},
pii = {EJN6674},
pmid = {19302165},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4834},
rating = {0}
}

@article{Nilsson:2002,
author = {J E Nilsson and C K Schmidt and W D Meek},
journal = {Educational and Psychological Measurement},
title = {Reliability Generalization: An examination of the Career Decision-making Self-efficacy Scale},
volume = {62},
year = {2002},
date-added = {2010-01-10 11:33:21 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2176},
rating = {0}
}

@article{McBane:2006p10899,
author = {G C McBane},
journal = {Journal of Statistical Software},
title = {Programs to Compute Distribution Functions and Critical Values for Extreme Value Ratios for Outlier Detection},
abstract = {A set of FORTRAN subprograms is presented to compute density and cumulative distribution functions and critical values for the range ratio statistics of Dixon (1951, The Annals of Mathematical Statistics) These statistics are useful for detection of outliers in small samples.},
number = {3},
volume = {16},
year = {2006},
date-added = {2010-04-11 13:46:47 +0200},
date-modified = {2010-04-11 13:47:17 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/McBane-2006-Journal%20of%20Statistical%20Software_Programs%20to%20Compute.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10899},
rating = {0}
}

@article{Tu:2008p7223,
author = {Yu-Kang Tu and Vibeke Baelum and Mark S Gilthorpe},
journal = {Eur J Oral Sci},
title = {A structural equation modelling approach to the analysis of change},
abstract = {Analysis of change is probably the most commonly adopted study design in medical and dental research when comparing the efficacy of two or more treatment modalities. The most commonly used methods for testing the difference in treatment efficacy are the two-sample t-test and the analysis of covariance (ANCOVA). It has been suggested that ancova should be used in the analysis of change for data from randomized controlled trials (RCTs) as a result of its greater statistical power. However, it is less well known that although both methods will give rise to similar results in the analysis of change for RCTs, there are different assumptions behind these methods in terms of the relationship between baseline value and the subsequent change, and the results may therefore differ if baseline values are not balanced between groups. This article uses structural equation modelling as a conceptual framework to explain the assumptions behind these methods, and two examples are used to show when the two methods yield similar results and why, in some non-randomized studies, the two methods might give substantially different results, known as 'Lord's paradox' in the statistical literature. For the appropriate interpretation of non-randomized studies, the assumptions underlying these methods therefore need to be taken into consideration.},
affiliation = {Department of Periodontology, Leeds Dental Institute, University of Leeds, Leeds, UK. y.k.tu@leeds.ac.uk},
number = {4},
pages = {291--6},
volume = {116},
year = {2008},
month = {Aug},
language = {eng},
keywords = {Dental Research, Regression Analysis, Multivariate Analysis, Randomized Controlled Trials as Topic, Controlled Clinical Trials as Topic, Outcome Assessment (Health Care), Humans, Models: Statistical},
date-added = {2010-03-08 19:32:53 +0100},
date-modified = {2010-03-08 19:32:53 +0100},
doi = {10.1111/j.1600-0722.2008.00549.x},
pii = {EOS549},
pmid = {18705795},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7223},
rating = {0}
}

@article{So:1995p13551,
author = {Y So and W F Kuhfeld},
title = {Multinomial Logit Models},
abstract = {Multinomial logit models are used to model relationships between a polytomous response variable and a set of regressor variables. The term ``multinomial logit model'' includes, in a broad sense, a variety of models. The cumulative logit model is used when the response of an individual unit is restricted to one of a finite number of ordinal values. Generalized logit and conditional logit models are used to model consumer choices. This article focuses on the statistical techniques for analyzing discrete choice data and discusses fitting these models using SAS/STAT software.},
year = {1995},
date-added = {2010-07-07 21:13:12 +0200},
date-modified = {2010-07-07 21:14:13 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/So-1995-_Multinomial%20Logit%20Mo.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13551},
rating = {0}
}

@article{Hardle:1997p12021,
author = {W H{\"a}rdle and M M{\"u}ller},
title = {Multivariate and semiparametric kernel regression},
year = {1997},
date-added = {2010-05-24 10:13:52 +0200},
date-modified = {2010-05-24 10:14:31 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/H%C3%A4rdle-1997-_Multivariate%20and%20sem.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12021},
rating = {0}
}

@article{Dunn:1999,
author = {G Dunn and A Pickles and M Tansella and JL Vazquez-Barquero},
journal = {British Journal of Psychiatry},
title = {Two-phase epidemiological surveys in psychiatric research},
pages = {95--100},
volume = {174},
year = {1999},
date-added = {2010-01-03 19:36:09 +0100},
date-modified = {2010-07-29 19:22:27 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1063},
rating = {0}
}

@article{Tebbens:2007p12891,
author = {Jurjen Duintjer Tebbens and Pavel Schlesinger},
journal = {Computational Statistics},
title = {Improving implementation of linear discriminant analysis for the high dimension/small sample size problem},
abstract = {Classification based on Fisher's linear discriminant analysis (FLDA) is challenging when the number of variables largely exceeds the number of given samples. The original FLDA needs to be carefully modified and with high dimensionality implementation issues like reduction of storage costs are of crucial importance. Methods are reviewed for the high dimension/small sample size problem and the one closest, in some sense, to the classical regular approach is chosen. The implementation of this method with regard to computational and storage costs and numerical stability is improved. This is achieved through combining a variety of known and new implementation strategies. Experiments demonstrate the superiority, with respect to both overall costs and classification rates, of the resulting algorithm compared with other methods.},
pages = {423--437},
volume = {52},
year = {2007},
date-added = {2010-06-24 13:24:29 +0200},
date-modified = {2010-07-29 19:24:30 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Tebbens-2007-Computational%20Statistics_Improving%20implementa.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12891},
rating = {4}
}

@article{Hastie2000,
author = {T Hastie and T Tibshirani and M B Eisen and A Alzadeh and R Levy and L Staudt and W C Chan and D Botstein and P O Brown},
journal = {Genome Biol},
title = {`Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns},
number = {2},
pages = {1--21},
volume = {1},
year = {2000},
date-added = {2010-01-12 14:26:40 +0100},
date-modified = {2010-07-29 19:27:22 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2522},
rating = {0}
}

@article{MacCallum:1999p11744,
author = {R C MacCallum and K F Widaman and S Zhang and S Hong},
journal = {Psychological Methods},
title = {Sample Size in Factor Analysis},
abstract = {The factor analysis literature includes a range of recommendations regarding the minimum sample size necessary to obtain factor solutions that are adequately stable and that correspond closely to population factors. A fundamental misconception about this issue is that the minimum sample size, or the minimumratio of sample size to the number of variables, is invariant across studies. In fact, necessary sample size is dependent on several aspects of any given study, including the level of communality of the variables and the level of overdetermination of the factors. The authors present a theoretical and mathematical framework that provides a basis for understanding and predicting these effects. The hypothesized effects are verified by a sampling study using artificial data. Results demonstrate the lack of validity of common rules of thumb and provide a basis for establishingguidelinesfor sample size in factor analysis.},
number = {1},
pages = {84--99},
volume = {4},
year = {1999},
date-added = {2010-05-14 21:37:30 +0200},
date-modified = {2010-05-14 21:38:39 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/MacCallum-1999-Psychological%20Methods_Sample%20Size%20in%20Facto.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11744},
rating = {4}
}

@article{Airoldi:2008p6277,
author = {E M Airoldi and D M Blei and S E Fienberg and E P Xing},
journal = {Journal of Machine Learning},
title = {Mixed Membership Stochastic Blockmodels},
abstract = {Consider data consisting of pairwise measurements, such as presence or absence of links between pairs of objects. These data arise, for instance, in the analysis of protein interactions and gene regulatory networks, collections of author-recipient email, and social networks. Analyzing pair- wise measurements with probabilistic models requires special assumptions, since the usual inde- pendence or exchangeability assumptions no longer hold. Here we introduce a class of variance allocation models for pairwise measurements: mixed membership stochastic blockmodels. These models combine global parameters that instantiate dense patches of connectivity (blockmodel) with local parameters that instantiate node-specific variability in the connections (mixed membership). We develop a general variational inference algorithm for fast approximate posterior inference. We demonstrate the advantages of mixed membership stochastic blockmodels with applications to so- cial networks and protein interaction networks.},
pages = {1981--2014},
volume = {9},
year = {2008},
date-added = {2010-02-20 17:54:19 +0100},
date-modified = {2010-07-29 19:34:44 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Airoldi-2008-Journal%20of%20Machine%20Learning_Mixed%20Membership%20Sto.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6277},
rating = {0}
}

@article{Porjesz:2007p9647,
author = {Bernice Porjesz and Madhavi Rangaswamy},
journal = {ScientificWorldJournal},
title = {Neurophysiological endophenotypes, CNS disinhibition, and risk for alcohol dependence and related disorders},
abstract = {Biological endophenotypes are more proximal to gene function than psychiatric diagnosis, providing a powerful strategy in searching for genes in psychiatric disorders. These intermediate phenotypes identify both affected and unaffected members of an affected family, including offspring at risk, providing a more direct connection with underlying biological vulnerability. The Collaborative Study on the Genetics of Alcoholism (COGA) has employed heritable neurophysiological features (i.e., brain oscillations) as endophenotypes, making it possible to identify susceptibility genes that may be difficult to detect with diagnosis alone. We found significant linkage and association between brain oscillations and genes involved with inhibitory neural networks (e.g., GABRA2, CHRM2), including frontal networks that are deficient in individuals with alcohol dependence, impulsivity, and related disinhibitory disorders. We reported significant linkage and linkage disequilibrium for the beta frequency of the EEG and GABRA2, a GABAA receptor gene on chromosome 4, which we found is also associated with diagnosis of alcohol dependence and related disorders. More recently, we found significant linkage and association with GABRA2 and interhemispheric theta coherence. We also reported significant linkage and linkage disequilibrium between the theta and delta event-related oscillations underlying P3 to target stimuli and CHRM2, a cholinergic muscarinic receptor gene on chromosome 7, which we found is also associated with diagnosis of alcohol dependence and related disorders. Thus, the identification of genes important for the expression of the endophenotypes (brain oscillations) helps when identifying genes that increase the susceptibility for risk of alcohol dependence and related disorders. These findings underscore the utility of quantitative neurophysiological endophenotypes in the study of the genetics of complex disorders. We will present our recent genetic findings related to brain oscillations and Central Nervous System (CNS) disinhibition.},
affiliation = {Henri Begleiter Neurodynamics Laboratory, SUNY Downstate Medical Center, Brooklyn, New York, USA. bp@cns.hscbklyn.edu},
note = {genim},
pages = {131--41},
volume = {7},
year = {2007},
month = {Jan},
language = {eng},
keywords = {Animals, Humans, Alcoholism, Neurophysiology, Phenotype, Central Nervous System, Risk Factors},
date-added = {2010-03-25 14:57:44 +0100},
date-modified = {2010-03-25 18:20:30 +0100},
doi = {10.1100/tsw.2007.203},
pmid = {17982586},
URL = {http://www.thescientificworld.co.uk/TSW/toc/TSWJ_ArticleLanding.asp?ArticleId=2679},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Porjesz-2007-ScientificWorldJournal_Neurophysiological%20e.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9647},
read = {Yes},
rating = {0}
}

@article{Fan:2009p2941,
author = {Yingying Fan},
journal = {arXiv},
title = {A unified approach to model selection and sparse recovery using  regularized least squares},
abstract = { Model selection and sparse recovery are two important problems for which many regularization methods have been proposed. We study the properties of regularization methods in both problems under the unified framework of regularized least squares with concave penalties. For model selection, we establish conditions under which a regularized least squares estimator enjoys a nonasymptotic property, called the weak oracle property, where the dimensionality can grow exponentially with sample size. For sparse recovery, we present a sufficient condition that ensures the recoverability of the sparsest solution. In particular, we approach both problems by considering a family of penalties that give a smooth homotopy between {\$}L_0{\$} and {\$}L_1{\$} penalties. We also propose the sequentially and iteratively reweighted squares (SIRS) algorithm for sparse recovery. Numerical studies support our theoretical results and demonstrate the advantage of our new methods for model selection and sparse recovery. },
annote = {Published in: Annals of Statistics 2009, Vol. 37, No. 6A, 3498-3528

Published in at http://dx.doi.org/10.1214/09-AOS683 the Annals of
  Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
  Statistics (http://www.imstat.org)},
eprint = {0905.3573v2},
volume = {math.ST},
year = {2009},
month = {Jan},
keywords = {stat.TH, 62J99 (Primary) 62F99 (Secondary), math.ST},
date-added = {2010-01-13 23:00:28 +0100},
date-modified = {2010-01-13 23:00:28 +0100},
doi = {10.1214/09-AOS683},
pmid = {0905.3573v2},
URL = {http://arxiv.org/abs/0905.3573v2},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fan-2009-arXiv_A%20unified%20approach%20t.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2941},
rating = {0}
}

@inbook{Rosenthal:1994,
author = {R Rosenthal},
journal = {Book},
title = {The handbook of research synthesis},
chapter = {Parametric measures of effect size},
year = {1994},
date-added = {2010-01-10 11:33:21 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1945},
rating = {0}
}

@article{Jirtle2007,
author = {R Jirtle and M Skinner},
journal = {Nat Rev Genet},
title = {Environmental epigenomics and disease susceptibility},
pages = {253--262},
volume = {8},
year = {2007},
date-added = {2010-01-12 14:26:52 +0100},
date-modified = {2010-07-29 19:40:47 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2537},
rating = {0}
}

@article{Palermo:2008p4452,
author = {Tonya M Palermo and Anna C Long and Amy S Lewandowski and Dennis Drotar and Alexandra L Quittner and Lynn S Walker},
journal = {J Pediatr Psychol},
title = {Evidence-based assessment of health-related quality of life and functional impairment in pediatric psychology},
abstract = {OBJECTIVE: To provide an evidence-based review of measures of health-related quality of life (HRQOL) and functional impairment, with a specific focus on their use in the field of pediatric psychology. METHODS: As part of a larger survey of pediatric psychologists from the Society of Pediatric Psychology e-mail listserv (American Psychological Association, APA, Division 54), 16 measures were selected for this psychometric review. Measures that qualified for the review fell into one of the following three categories: (a) generic HRQOL scales, (b) disease-specific quality of life scales, and (c) functional impairment rating scales. RESULTS: Psychometric characteristics (i.e., three types of reliability, two types of validity) were strong for the majority of measures reviewed, with 12 of the 16 measures meeting "well-established" evidence-based assessment criteria. Strengths and weaknesses of existing measures were noted. CONCLUSIONS: Recommendations for future work in this area of assessment are presented, including suggestions that further validation and exploration of measure properties such as factor analysis and changes in HRQOL over time be conducted.},
affiliation = {Oregon Health {\&} Science University, Department of Anesthesiology, 3181 SW Sam Jackson Park Road UHS-2, Portland, OR 97239, USA.},
number = {9},
pages = {983-96; discussion 997--8},
volume = {33},
year = {2008},
month = {Oct},
language = {eng},
keywords = {Quality of Life, Humans, Activities of Daily Living, Health Status Indicators, Disability Evaluation, Child, Reproducibility of Results, Chronic Disease, Questionnaires},
date-added = {2010-01-29 21:37:34 +0100},
date-modified = {2010-07-29 19:35:17 +0200},
doi = {10.1093/jpepsy/jsn038},
pii = {jsn038},
pmid = {18430762},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Palermo-2008-J%20Pediatr%20Psychol_Evidence-based%20asses.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4452},
rating = {0}
}

@article{Berg:2007,
author = {S M van den Berg and C A W Glas and Dorret I Boomsma},
journal = {Behav Genet},
title = {Variance decomposition using an IRT measurement model},
pages = {604--616},
volume = {37},
year = {2007},
date-added = {2010-01-10 11:33:22 +0100},
date-modified = {2010-07-29 20:25:51 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Berg-2007-Behav%20Genet_Variance%20decompositi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1989},
rating = {0}
}

@article{Foulkes:2008p4695,
author = {Andrea S Foulkes and Recai Yucel and Xiaohong Li},
journal = {Biostatistics},
title = {A likelihood-based approach to mixed modeling with ambiguity in cluster identifiers},
abstract = {This manuscript describes a novel, linear mixed-effects model-fitting technique for the setting in which correlated data indicators are not completely observed. Mixed modeling is a useful analytical tool for characterizing genotype-phenotype associations among multiple potentially informative genetic loci. This approach involves grouping individuals into genetic clusters, where individuals in the same cluster have similar or identical multilocus genotypes. In haplotype-based investigations of unrelated individuals, corresponding cluster assignments are unobservable since the alignment of alleles within chromosomal copies is not generally observed. We derive an expectation conditional maximization approach to estimation in the mixed modeling setting, where cluster assignments are ambiguous. The approach has broad relevance to the analysis of data with missing correlated data identifiers. An example is provided based on data arising from a cohort of human immunodeficiency virus type-1-infected individuals at risk for antiretroviral therapy-associated dyslipidemia.},
affiliation = {Division of Biostatistics, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA. foulkes@schoolph.umass.edu},
number = {4},
pages = {635--57},
volume = {9},
year = {2008},
month = {Oct},
language = {eng},
keywords = {Genome-Wide Association Study, Male, Likelihood Functions, Hispanic Americans, Genotype, Models: Statistical, Humans, Phenotype, Haplotypes, HIV-1, Models: Genetic, Antiretroviral Therapy: Highly Active, Computer Simulation, Linear Models, Algorithms, Female, Polymorphism: Single Nucleotide, Cardiovascular Diseases, HIV Infections, Statistical Distributions, Gene Frequency, Dyslipidemias},
date-added = {2010-01-30 16:17:28 +0100},
date-modified = {2010-01-30 16:17:28 +0100},
doi = {10.1093/biostatistics/kxm055},
pii = {kxm055},
pmid = {18343883},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Foulkes-2008-Biostatistics_A%20likelihood-based%20a.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4695},
rating = {0}
}

@article{Tucker:1997,
author = {C Tucker},
journal = {Bulletin de M{\'e}thodologie Sociologique},
title = {Measurement issues surrounding the application of cognitive psychology in survey research},
abstract = {Dans l'empressement {\`a} appliquer la psychologie cognitive et ses m{\'e}thodes dans la recherche sociale par questionnaire pendant la derni{\`e}re d{\'e}cennie, une attention insuffisante a {\'e}t{\'e} donn{\'e}e aux principes scientifiques. Cet article fournit un cadre pour corriger ce probl{\`e}me en se concentrant sur des m{\'e}thodes qui peuvent am{\'e}liorer la validit{\'e} et la fiabilit{\'e} des donn{\'e}es collect{\'e}es avec l'appui de la psychologie cognitive. Ces m{\'e}thodes utilisent de meilleurs plans d'exp{\'e}riences et de meilleures techniques de mesure. Des plans d'exp{\'e}riences qui facilitent la comparaison entre des proc{\'e}dures cognitives alternatives et des travaux de chercheurs diff{\'e}rents sont pr{\'e}sent{\'e}s. Un autre aspect de ces plans est qu'ils demandent plus d'attention dans l'{\'e}laboration du protocole exp{\'e}rimental. En ce qui concerne la mesure, des techniques pour rendre l'utilisation des donn{\'e}es qualitatives plus syst{\'e}matique sont discut{\'e}es, et des m{\'e}thodes de construction d'indicateurs ordinaux et d'intervalle sont pr{\'e}sent{\'e}es},
pages = {67--92},
volume = {55},
year = {1997},
date-added = {2010-01-03 19:34:17 +0100},
date-modified = {2010-01-03 19:34:18 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p942},
rating = {0}
}

@article{Kumari:2007p7506,
author = {A Krishna Kumari and K Krishnamoorthy and Kt Harichandrakumar and Lk Das},
journal = {Filaria J},
title = {Health Related Quality of Life, an appropriate indicator to assess the impact of morbidity management and disability prevention activities towards elimination of lymphatic filariasis},
abstract = {BACKGROUND: Lymphatic filariasis has been identified as one of the six diseases that can be potentially eliminated. Global programme to eliminate lymphatic filariasis has been launched, applying principal strategies of mass drug administration to interrupt transmission and morbidity management to prevent disability. The strategy for mass drug administration has been clearly laid out and guidelines have been well documented for implementation, monitoring and evaluation of the programme but such a guideline is warranted for morbidity management and disability prevention activities. DISCUSSION: Health Related Quality of Life, a multidimensional construct referring to patients' perceptions of the impact of disease and treatment on their physical, psychological and social function and well being is crucial in the evaluation of health care interventions. Lymphatic filariasis has a wide clinical spectrum and disability is more pronounced in the advanced stages of lymphoedema and hydrocele. Since the advanced stages of lymphoedema are not reversible, morbidity management and disability prevention activities can lessen the disabilities due to secondary infections and there by improve the quality of life of the patient. Thus, an improvement in quality of life is considered to be important as a primary outcome in the determination of therapeutic benefit. Therefore it can be used as an indicator to assess the impact of morbidity management and disability prevention activities in global programme to eliminate lymphatic filariasis. SUMMARY: Disease specific Health Related Quality of Life instrument can be used to measure the longitudinal changes in quality of life of patients following the intervention. High responsiveness, clinical relevance to patients and its sensitiveness to detect small changes are the merits of disease specific instrument. Morbidity management and disability prevention activities under filariasis elimination programme aim at improving the quality of life of patients with irreversible manifestations. Therefore there is an urgent need to develop an instrument to assess the health related quality of life, specific for lymphatic filariasis by incorporating all the difficulties and problems caused to patients by the disease in the physical, mental and social domains of health.},
affiliation = {Division of Health Economics and Disease Burden, Vector Control Research Centre, Pondicherry, India. kkrish_3@yahoo.com},
pages = {8},
volume = {6},
year = {2007},
month = {Jan},
language = {eng},
date-added = {2010-03-10 20:47:43 +0100},
date-modified = {2010-03-10 20:47:43 +0100},
doi = {10.1186/1475-2883-6-8},
pii = {1475-2883-6-8},
pmid = {17723155},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kumari-2007-Filaria%20J_Health%20Related%20Quali.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7506},
rating = {0}
}

@article{Box:1980,
author = {Box},
journal = {American Statistics},
title = {RA Fisher and the design of experiments, 1922--1926},
abstract = {This article traces the development of the design of experiments from origins in the mind and professional experience of R.A. Fisher between 1922 and 1926. The article indicates how the analysis of variance procedure stimulated design, being justified by the principle of randomization that Fisher introduced with the analysis, and exploited by his use of blocking and replication. The article indicates the radically new form and efficiency of factorial block designs, shows the further advantages accruing to factorial arrangements through confounding, and suggests how Fisher's close collaboration with experimenters stimulated these developments.},
pages = {1--7},
volume = {34},
year = {1980},
date-added = {2010-01-03 19:36:10 +0100},
date-modified = {2010-01-03 19:36:10 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1067},
rating = {0}
}

@article{Phuong:2006p3928,
author = {Tu Minh Phuong and Zhen Lin and Russ B Altman},
journal = {J Bioinform Comput Biol},
title = {Choosing SNPs using feature selection},
abstract = {A major challenge for genomewide disease association studies is the high cost of genotyping large number of single nucleotide polymorphisms (SNPs). The correlations between SNPs, however, make it possible to select a parsimonious set of informative SNPs, known as "tagging" SNPs, able to capture most variation in a population. Considerable research interest has recently focused on the development of methods for finding such SNPs. In this paper, we present an efficient method for finding tagging SNPs. The method does not involve computation-intensive search for SNP subsets but discards redundant SNPs using a feature selection algorithm. In contrast to most existing methods, the method presented here does not limit itself to using only correlations between SNPs in local groups. By using correlations that occur across different chromosomal regions, the method can reduce the number of globally redundant SNPs. Experimental results show that the number of tagging SNPs selected by our method is smaller than by using block-based methods. Supplementary website: http://htsnp.stanford.edu/FSFS/.},
affiliation = {Department of Information Technology, Posts {\&} Telecommunications Institute of Technology, Hanoi, Vietnam. phuongtm@fpt.com.vn},
number = {2},
pages = {241--57},
volume = {4},
year = {2006},
month = {Apr},
language = {eng},
keywords = {Base Sequence, Algorithms, Sequence Alignment, Molecular Sequence Data, Polymorphism: Single Nucleotide, Expressed Sequence Tags, Artificial Intelligence, Sequence Analysis: DNA, Pattern Recognition: Automated},
date-added = {2010-01-16 21:05:28 +0100},
date-modified = {2010-01-16 21:05:28 +0100},
pii = {S0219720006001941},
pmid = {16819782},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3928},
rating = {3}
}

@article{Heine:2008p11167,
author = {SJ Heine and E E Buchtel and A Norenzayan},
journal = {Psychol Sci},
title = {What Do Cross-National
Comparisons of Personality
Traits Tell Us? The Case of Conscientiousness},
abstract = {Much research contrasts self-reported per- sonality traits across cultures. We submit that this enter- prise is weakened by significant methodological problems (in particular, the reference-group effect) that undermine the validity of national averages of personality scores. In this study, behavioral and demographic predictors of con- scientiousness were correlated with different cross-nation- al measures of conscientiousness based on self-reports, peer reports, and perceptions of national character. The predictors correlated strongly with perceptions of national character, but not with self-reports and peer reports. Country-level self- and peer-report measures of conscien- tiousness failed as markers of between-nation differences in personality.},
number = {4},
pages = {309--313},
volume = {19},
year = {2008},
date-added = {2010-04-25 21:12:23 +0200},
date-modified = {2010-07-29 19:46:15 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Heine-2008-Psychol%20Sci_What%20Do%20Cross-Nation.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11167},
rating = {4}
}

@article{Larson:2010p5076,
author = {Tomas Larson and Henrik Anckarsater and Carina Gillberg and Ola Stahlberg and Eva Carlstrom and Bjorn Kadesjo and Maria Rastam and Paul Lichtenstein and Christopher Gillberg},
journal = {BMC Psychiatry},
title = {Screening for autism and AD/HD. The A-TAC: further validation of a telephone interview in clinical and population samples},
abstract = {ABSTRACT: BACKGROUND: Reliable, valid, and easy-to-administer instruments to identify possible caseness and to provide proxies for clinical diagnoses are needed in epidemiological research on child and adolescent mental health. The aim of this study is to provide further validity data for a parent telephone interview focused on Autism - Tics, Attention-deficit/hyperactivity disorder (AD/HD), and other Comorbidities (A-TAC), for which reliability and preliminary validation data have been previously reported. METHODS: Parents of 91 children clinically diagnosed at a specialized Child Neuropsychiatric Clinic, 366 control children and 319 children for whom clinical diagnoses had been previously assigned were interviewed by the A-TAC over the phone. Interviewers were blind to clinical information. Different scores from the A-TAC were compared to the diagnostic outcome. RESULTS: Areas under ROC curves for interview scores as predictors of clinical diagnoses were around 0.95 for most disorders, including autism spectrum disorders (ASDs), attention deficit/hyperactivity disorder (AD/HD), tic disorders, developmental coordination disorders (DCD) and learning disorders, indicating excellent screening properties. Screening cut-off scores with sensitivities above 0.90 (0.95 for ASD and AD/HD) were established for most conditions, as well as cut-off scores to identify proxies to clinical diagnoses with specificities above 0.90 (0.95 for ASD and AD/HD). CONCLUSIONS: The previously reported validity of the A-TAC was supported by this larger replication study using broader scales from the A-TAC-items and a larger number of diagnostic categories. Short versions of algorithms worked as well as larger. Different cut-off levels for screening versus identifying proxies for clinical diagnoses are warranted. Data on the validity for mood problems and oppositional defiant/conduct problems are still lacking. Although the A-TAC is principally intended for epidemiological research and general investigations, the instrument may be useful as a tool to collect information in clinical practice as well.},
number = {1},
pages = {1},
volume = {10},
year = {2010},
month = {Jan},
language = {ENG},
date-added = {2010-02-05 20:14:24 +0100},
date-modified = {2010-02-05 20:14:24 +0100},
doi = {10.1186/1471-244X-10-1},
pii = {1471-244X-10-1},
pmid = {20055988},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5076},
rating = {0}
}

@article{Boomsma:2002p5213,
author = {Dorret Boomsma and Andreas Busjahn and Leena Peltonen},
journal = {Nat Rev Genet},
title = {Classical twin studies and beyond},
abstract = {Twin studies have been a valuable source of information about the genetic basis of complex traits. To maximize the potential of twin studies, large, worldwide registers of data on twins and their relatives have been established. Here, we provide an overview of the current resources for twin research. These can be used to obtain insights into the genetic epidemiology of complex traits and diseases, to study the interaction of genotype with sex, age and lifestyle factors, and to study the causes of co-morbidity between traits and diseases. Because of their design, these registers offer unique opportunities for selected sampling for quantitative trait loci linkage and association studies.},
affiliation = {Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands. di.boomsma@psy.vu.nl},
number = {11},
pages = {872--82},
volume = {3},
year = {2002},
month = {Nov},
language = {eng},
keywords = {Female, Male, Genetic Research, Pedigree, Twin Studies as Topic, Humans},
date-added = {2010-02-08 19:26:54 +0100},
date-modified = {2010-07-29 19:40:47 +0200},
doi = {10.1038/nrg932},
pii = {nrg932},
pmid = {12415317},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Boomsma-2002-Nat%20Rev%20Genet_Classical%20twin%20studi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5213},
rating = {0}
}

@article{Fraiman:2008p1614,
author = {R Fraiman and A Justel and M Svarc},
title = {Selection of Variables for Cluster Analysis and Classification Rules},
abstract = {In this paper we introduce two procedures for variable selection in cluster analysis and classification rules. One is mainly oriented to de- tect the ``noisy'' non--informative variables, while the other also deals with multicolinearity and general dependence. Both methods are de- signed to be used after a ``satisfactory'' grouping procedure has been carried out. A forward--backward algorithm is proposed to make such procedures feasible in large data sets. A small simulation is performed and some real data examples are analyzed.},
year = {2008},
date-added = {2010-01-07 17:13:52 +0100},
date-modified = {2010-01-07 17:14:45 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fraiman-2008-_Selection%20of%20Variabl.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1614},
rating = {0}
}

@article{Kopp:1982p8588,
author = {C B Kopp and B E Vaughn},
journal = {Child Dev},
title = {Sustained attention during exploratory manipulation as a predictor of cognitive competence in preterm infants},
abstract = {Recent reviews of research on individual differences in cognitive status during infancy have led to the conclusion that early test performances do not predict later IQ in any clinically useful way. These conclusions seem to be true for both normal children and for children born at developmental risk. In order to test an alternative strategy in prediction of later cognitive status from infant behavioral performance, 76 preterm infants were assessed with respect to differences in sustained attention when they were 8 months old. Scores on this measure were entered into a performance on 4 test scores at 2 years of age. The measure of sustained attention proved to contribute significantly to the prediction of later status on the Bayley Mental Scale and on the Gesell schedules. These sustained-attention scores were not significantly predictive of the scores on a Piagetian-based cognitive test, or on a assessment of receptive language. Subsequent analyses of these data for each gender separately revealed that increments in prediction were found for males only. The results are discussed in terms of current information-processing approaches to the study of stability of individual differences in cognitive functioning.},
number = {1},
pages = {174--82},
volume = {53},
year = {1982},
month = {Feb},
language = {eng},
keywords = {Infant, Infant: Premature, Sex Factors, Attention, Cognition, Child: Preschool, Individuality, Exploratory Behavior, Motor Skills, Language, Humans, Social Class, Infant: Newborn, Risk},
date-added = {2010-03-22 00:10:37 +0100},
date-modified = {2010-03-22 00:10:37 +0100},
pmid = {7060420},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8588},
rating = {0}
}

@article{Holland:1986p6267,
author = {P W Holland and P R Rosenbaum},
journal = {The Annals of Statistics},
title = {Conditional Association and Unidimensionality in Monotone Latent Variable Models},
abstract = {Latent variable models represent the joint distribution of observable variables in terms of a simple structure involving unobserved or latent variables, usually assuming the conditional independence of the observ- able variables given the latent variables. These models play an important role in educational measurement and psychometrics, in sociology and in popula- tion genetics, and are implicit in some work on systems reliability. We study a broad class of latent variable models, namely the monotone unidimensional models, in which the latent variable is a scalar, the observable variables are conditionally independent given the latent variable and the conditional distribution of the observables given the latent variable is stochastically increasing in the latent variable. All models in this class imply a new strong form of positive dependence among the observable variables, namely condi- tional (positive) association. This positive dependence condition may be used to test whether any model in this class can provide an adequate fit'to observed data. Various applications, generalizationsand a numerical example are discussed.},
number = {4},
pages = {1523--1543},
volume = {14},
year = {1986},
date-added = {2010-02-19 21:57:47 +0100},
date-modified = {2010-02-19 22:04:32 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Holland-1986-The%20Annals%20of%20Statistics_Conditional%20Associat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6267},
rating = {0}
}

@article{Johnson:2007p1535,
author = {M S Johnson},
journal = {Computational Statistics},
title = {Modeling dichotomous item responses with free-knot splines},
abstract = {Item response theory (IRT) models are a class of generalized mixed effect (GME) models used by psychometricians to describe the response behavior of individuals to a set of categorically scored items. The typical assumptions of IRT are Unidimensionality (U) of the random effect; Conditional (or Local) Independence (CI), the item responses are independent given the random effect; and Monotonicity (M), the probability of a correct response is a non-decreasing function of the random effect. The simple parametric models available in the psychometric literature have proved to be too restrictive in many data sets. Non-parametric regression models are a powerful tool for the estimation of non-linear curves, and have been used in IRT as a flexible way to model the item response function. This paper develops a new method for the non-parametric estimation of item response functions based on reversible-jump Markov Chain Monte Carlo, and demonstrates the practicality of the method by examining two data sets.},
affiliation = {Department of Statistics and Computer Information Systems, Baruch College, City University of New York, USA},
pages = {4178--4192},
volume = {51},
year = {2007},
keywords = {Reversible-jump, B-spline functions, Item response theory, Psychometrics, Repeated dichotomous measures, Markov chain Monte Carlo},
date-added = {2010-01-07 16:14:30 +0100},
date-modified = {2010-07-29 19:24:31 +0200},
doi = {10.1016/j.csda.2006.04.021},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Johnson-2007-Computational%20Statistics_Modeling%20dichotomous.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1535},
rating = {0}
}

@article{Chen:2007p12807,
author = {X-W Chen and J C Jeong},
journal = {Proceedings of the 24dthInternational Conference on
Machine Learning},
title = {Minimum Reference Set Based Feature Selection for Small Sample
Classifications},
abstract = {We address feature selection problems for classification of small samples and high dimensionality.	A	practical	example	is microarray-based cancer classification problems, where sample size is typically less than 100 and number of features is several thousands or higher. One of the commonly used methods in addressing this problem is recursive feature elimination (RFE) method, which utilizes the generalization capability embedded in support vector machines and is thus suitable for small samples problems. We propose a novel method using minimum reference set (MRS) generated by the nearest neighbor rule. MRS is the set of minimum number of samples that correctly classify all the training samples. It is related to structural risk minimization principle and thus leads to good generalization. The proposed MRS based method is compared to RFE method with several real datasets, and experimental results show that the MRS method produces better classification performance.},
year = {2007},
date-added = {2010-06-18 22:53:43 +0200},
date-modified = {2010-06-18 22:54:27 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Chen-2007-Proceedings%20of%20the%2024dthInternational%20Conference%20on%0DMachine%20Learning_Minimum%20Reference%20Se.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12807},
rating = {0}
}

@article{Hahn:2010p12714,
author = {Elizabeth A Hahn and Hongyan Du and Sofia F Garcia and Seung W Choi and Jin-Shei Lai and David Victorson and David Cella},
journal = {Med Care},
title = {Literacy-fair measurement of health-related quality of life will facilitate comparative effectiveness research in Spanish-speaking cancer outpatients},
abstract = {BACKGROUND: Health-related quality of life (HRQL) assessment is frequently used in comparative effectiveness research, but low-literacy patients are often excluded. Appropriately translated and user-friendly HRQL measures are essential to ensure inclusion of low-literate and non-English-speaking patients in comparative effectiveness research. OBJECTIVES: To compare HRQL responses across literacy levels in Spanish-speaking patients with cancer using a multimedia touch screen program. SUBJECTS: A total of 414 adult patients with cancer (213 with low literacy and 201 with high literacy). RESEARCH DESIGN: The touch screen system administered 3 questionnaires: The Functional Assessment of Cancer Therapy-General, the Short Form-36 Health Survey, and the Standard Gamble Utility Questionnaire. Measurement bias was evaluated using item response theory. Effects of literacy on HRQL were evaluated using regression models. RESULTS: Patients rated the touch screen easy to use and commented favorably on the multimedia approach. There was statistically significant item response theory measurement bias in 6 of 10 HRQL subscales; however, only 3 showed meaningful bias. Low-literacy patients had significantly lower mean scores on 3 of 4 Functional Assessment of Cancer Therapy-General subscales, before and after adjustment for patient characteristics. Low-literacy patients also had significantly lower mean scores on 5 of 6 Short Form-36 subscales; adjustment for patient characteristics attenuated or eliminated differences. Similar proportions of low- and high-literacy patients valued their current health as equivalent to perfect health. CONCLUSIONS: This study demonstrates the feasibility of this multimedia touch screen program for low-literacy patients. The program will provide opportunities to evaluate the effectiveness of interventions in more diverse patient populations.},
affiliation = {Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. e-hahn@northwestern.edu},
number = {6 Suppl},
pages = {S75--82},
volume = {48},
year = {2010},
month = {Jun},
language = {eng},
date-added = {2010-06-15 22:47:58 +0200},
date-modified = {2010-07-29 19:39:29 +0200},
doi = {10.1097/MLR.0b013e3181d6f81b},
pmid = {20473208},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12714},
rating = {0}
}

@article{Morales:2000p1832,
author = {L S Morales and S P Reise and R D Hays},
journal = {Med Care},
title = {Evaluating the equivalence of health care ratings by whites and Hispanics},
abstract = {PURPOSE: This study was designed to assess the equivalence of a health care ratings scale administered to non-Hispanic white and Hispanic survey respondents. METHODS: We sent 18,840 questionnaires to a random sample of patients receiving medical care from a physician group association concentrated in the western United States; 7,093 were returned (59% adjusted response rate). Approximately 90% of survey respondents self-identified as white/Caucasian (n = 5,508) or Hispanic/Latino (n = 713). Interpersonal and technical aspects of medical care were assessed with 9 items, all administered with a 7-point response format: the best, excellent, very good, good, fair, poor, and very poor, with a "not applicable" option. Item response theory procedures were used to test for differential item functioning between white and Hispanic respondents. RESULTS: Hispanics were found to be significantly more dissatisfied with care than whites (effect size=0.27; P <0.05). Of the 9 test items, 2 had statistically significant differential item functioning (P <0.05): reassurance and support offered by your doctors and staff and quality of examinations received. However, summative scale scores and test characteristic curves for whites and Hispanics were similar whether or not these items were included in the scale. CONCLUSIONS: Despite some differences in item functioning, valid satisfaction-with-care comparisons between whites and Hispanics are possible. Thus, disparities in satisfaction ratings between whites and Hispanics should not be ascribed to measurement bias but should be viewed as arising from actual differences in experiences with care.},
affiliation = {University of California at Los Angeles, 90095-1736, USA. morales@rand.org},
number = {5},
pages = {517--27},
volume = {38},
year = {2000},
month = {May},
language = {eng},
keywords = {Hispanic Americans, Middle Aged, European Continental Ancestry Group, Delivery of Health Care, Psychometrics, Models: Statistical, Adult, Female, Aged, Male, Random Allocation, Humans, United States, Questionnaires, Patient Satisfaction},
date-added = {2010-01-09 23:00:24 +0100},
date-modified = {2010-07-29 19:39:29 +0200},
pmid = {10800978},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1832},
rating = {0}
}

@article{Harasym:2008p5922,
author = {Peter H Harasym and Wayne Woloschuk and Leslie Cunning},
journal = {Adv Health Sci Educ Theory Pract},
title = {Undesired variance due to examiner stringency/leniency effect in communication skill scores assessed in OSCEs},
abstract = {Physician-patient communication is a clinical skill that can be learned and has a positive impact on patient satisfaction and health outcomes. A concerted effort at all medical schools is now directed at teaching and evaluating this core skill. Student communication skills are often assessed by an Objective Structure Clinical Examination (OSCE). However, it is unknown what sources of error variance are introduced into examinee communication scores by various OSCE components. This study primarily examined the effect different examiners had on the evaluation of students' communication skills assessed at the end of a family medicine clerkship rotation. The communication performance of clinical clerks from Classes 2005 and 2006 were assessed using six OSCE stations. Performance was rated at each station using the 28-item Calgary-Cambridge guide. Item Response Theory analysis using a Multifaceted Rasch model was used to partition the various sources of error variance and generate a "true" communication score where the effects of examiner, case, and items are removed. Variance and reliability of scores were as follows: communication scores (.20 and .87), examiner stringency/leniency (.86 and .91), case (.03 and .96), and item (.86 and .99), respectively. All facet scores were reliable (.87-.99). Examiner variance (.86) was more than four times the examinee variance (.20). About 11% of the clerks' outcome status shifted using "true" rather than observed/raw scores. There was large variability in examinee scores due to variation in examiner stringency/leniency behaviors that may impact pass-fail decisions. Exploring the benefits of examiner training and employing "true" scores generated using Item Response Theory analyses prior to making pass/fail decisions are recommended.},
affiliation = {Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada.},
number = {5},
pages = {617--32},
volume = {13},
year = {2008},
month = {Dec},
language = {eng},
keywords = {Clinical Competence, Logistic Models, Male, Reproducibility of Results, Judgment, Educational Measurement, Family Practice, Faculty: Medical, Clinical Clerkship, Observer Variation, Communication, Humans, Female, Self Concept},
date-added = {2010-02-18 23:12:19 +0100},
date-modified = {2010-07-29 19:12:44 +0200},
doi = {10.1007/s10459-007-9068-0},
pmid = {17610034},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5922},
rating = {0}
}

@article{Wilkinson:1999p11765,
author = {Leland Wilkinson and TFoSI},
journal = {American Psychologist},
title = {Statistical Methods in Psychology Journals: Guidelines and Explanations},
number = {8},
pages = {594--604},
volume = {54},
year = {1999},
date-added = {2010-05-23 10:13:08 +0200},
date-modified = {2010-05-23 10:14:12 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wilkinson-1999-American%20Psychologist_Statistical%20Methods.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11765},
rating = {0}
}

@article{Jain:2000p3322,
author = {Anil K Jain and Robert P. W Duin and Jianchang Mao},
title = {Statistical Pattern Recognition: A Review},
abstract = {this article, please send e-mail to:tpami@computer.org, and reference IEEECS Log Number 110296},
year = {2000},
month = {Aug},
language = {eng},
date-added = {2010-01-15 12:10:57 +0100},
date-modified = {2010-01-15 12:10:57 +0100},
pmid = {710465},
URL = {http://citeseer.ist.psu.edu/710465},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Jain-2000-_Statistical%20Pattern.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3322},
rating = {0}
}

@article{Rakhlin:2006p12948,
author = {A Rakhlin and A Caponnetto},
title = {Stability of K-Means Clustering},
abstract = {We phrase K-means clustering as an empirical risk minimization procedure over a class HK and explicitly calculate the covering number for this class. Next, we show that stability of K-means clustering is characterized by the geometry of HK with respect to the underlying distribution. We prove that in the case of a unique global minimizer, the clustering solution is stable with respect to complete changes of the data, while for the case of multiple minimizers, the change of Ω(n1/2) samples defines the transition between stability and instability. While for a finite number of minimizers this result follows from multinomial distribution estimates, the case of infinite minimizers requires more refined tools. We conclude by proving that stability of the functions in HK implies stability of the actual centers of the clusters. Since stability is often used for selecting the number of clusters in practice, we hope that our analysis serves as a starting point for finding theoretically grounded recipes for the choice of K.},
year = {2006},
date-added = {2010-06-25 22:03:32 +0200},
date-modified = {2010-06-25 22:04:35 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rakhlin-2006-_Stability%20of%20K-Means.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12948},
rating = {0}
}

@article{Revicki:2007p7862,
author = {Dennis A Revicki and Jeff Sloan},
journal = {Qual Life Res},
title = {Practical and philosophical issues surrounding a national item bank: if we build it will they come?},
abstract = {Item response theory (IRT), item banking and computer adaptive testing (CAT) methods have the potential to provide novel platforms for the collection, analysis and dissemination of patient data on health status and well-being. There are considerable challenges associated with building and maintaining a national item bank and it is uncertain whether there is sufficient interest among key stakeholders for IRT-based and CAT measures. The most convincing activity is demonstrating that the approach is feasible, psychometrically sound and useful in different specific applications. Demonstrated success opens up the possibility of more widespread acceptability and application. As part of the development effort, there needs to be continued meetings and discussion with psychometricians, instrument developers, clinical researchers, the FDA, pharmaceutical industry researchers and a managed care organizations about the advantages and disadvantages of a national item bank.},
affiliation = {Center for Health Outcomes Research, United BioSource Corporation, 7101 Wisconsin Ave., Suite 600, Bethesda, MD 20814, USA. dennis.revicki@unitedbiosource.com},
pages = {167--74},
volume = {16 Suppl 1},
year = {2007},
month = {Jan},
language = {eng},
keywords = {Quality of Life, Drug Industry, United States, Computer Systems, United States Food and Drug Administration, Questionnaires, Outcome Assessment (Health Care), Databases as Topic, Health Status, Software, Humans, Psychometrics},
date-added = {2010-03-20 19:00:40 +0100},
date-modified = {2010-07-29 19:48:30 +0200},
doi = {10.1007/s11136-007-9218-0},
pmid = {17468940},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7862},
rating = {0}
}

@article{Garcia:2008p544,
author = {S Garcia and Francisco Herrera},
journal = {Journal of Machine Learning},
title = {An Extension on ``Statistical Comparisons of Classifiers over Multiple Data Sets'' for all Pairwise Comparisons},
abstract = {In a recently published paper in JMLR, Demsar (2006) recommends a set of non-parametric statistical tests and procedures which can be safely used for comparing the performance of classifiers over multiple data sets. After studying the paper, we realize that the paper correctly introduces the basic procedures and some of the most advanced ones when comparing a control method. However, it does not deal with some advanced topics in depth. Regarding these topics, we focus on more powerful proposals of statistical procedures for comparing n × n classifiers. Moreover, we illustrate an easy way of obtaining adjusted and comparable p-values in multiple comparison procedures.},
affiliation = {Department of Computer Science and Artificial Intelligence University of Granada Granada, 18071, Spain},
pages = {2677--2694},
volume = {9},
year = {2008},
keywords = {non-parametrictest, statisticalmethods, adjustedp-values, logically related hypotheses, multiplecomparisonstests},
date-added = {2010-01-03 14:14:42 +0100},
date-modified = {2010-07-29 19:34:45 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Garcia-2008-Journal%20of%20Machine%20Learning_An%20Extension%20on%20%E2%80%9CSta.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p544},
rating = {0}
}

@article{Shang:2010p10925,
author = {Ning-Xiu Shang and Li-Ping Zou and Jian-Bo Zhao and Feng Zhang and Hua Li},
journal = {Pediatr Neurol},
title = {Association between prenatal stress and infantile spasms: a case-control study in China},
abstract = {The present study investigated a possible correlation between prenatal stress and the onset of infantile spasms. A total of 120 infants (60 cases, 30 positive controls, and 30 negative controls) went through routine etiologic screening. The Pregnant Woman Life Event Scale was used to investigate and evaluate the degree of prenatal stress of the mothers in the three infant groups. Etiologic analyses indicated no statistical difference between the infantile spasms group and the other epilepsy control group. There was a significant difference in the degree of prenatal stress among mothers of the three infant groups, with higher maternal prenatal stress levels in the infantile spasms group than in the other epilepsy group (positive control) or the normal control group (P < 0.05). Regression analysis with the dummy variable indicated that the onset risk of infantile spasms correspondingly increased with the degree of maternal prenatal stress for stress levels 1-3 (out of four levels) (P < 0.05). Within a certain range, the onset risk of infantile spasms increases with the degree of prenatal stress.},
affiliation = {Department of Neurology, Capital Institute of Pediatrics, Beijing, China.},
number = {3},
pages = {181--6},
volume = {42},
year = {2010},
month = {Mar},
language = {eng},
date-added = {2010-04-13 16:22:15 +0200},
date-modified = {2010-04-13 16:22:15 +0200},
doi = {10.1016/j.pediatrneurol.2009.09.003},
pii = {S0887-8994(09)00435-4},
pmid = {20159427},
URL = {http://linkinghub.elsevier.com/retrieve/pii/S0887-8994(09)00435-4},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Shang-2010-Pediatr%20Neurol_Association%20between.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10925},
rating = {0}
}

@article{Caravale:2005p5009,
author = {B Caravale and C Tozzi and G Albino and S Vicari},
journal = {Arch Dis Child Fetal Neonatal Ed},
title = {Cognitive development in low risk preterm infants at 3-4 years of life},
abstract = {BACKGROUND: Major neurological handicaps and neuropsychological disturbances are more common in ex-preterm children than their counterparts born at term. OBJECTIVE: To establish in a prospective study whether a characteristic neuropsychological profile exists in ex-preterm children who do not exhibit neurodevelopmental deficits on routine clinical examination. METHODS: Thirty intellectually normal children born preterm (30-34 weeks gestation) without major neurological disabilities and a control group of term children matched for age, sex, and parental educational and occupational status were assessed at 3-4 years of age to obtain a complete neuropsychological profile. Intellectual ability, language comprehension and expression, perceptual and visual motor function, working memory, and attention and behavioural problems were investigated. RESULTS: Even in the absence of major neurological signs, children born preterm achieved lower mean scores than controls on the Stanford-Binet intelligence scale (110.8 v 121, p<0.001), visual perception test (33.8 v 42.7, p<0.001), visual motor integration test (42.6 v 47.4, p = 0.049), memory for location test (8.4 v 9.5, p = 0.007), sustained attention test (41.6 v 51.5, p = 0.009), and the picture vocabulary test (33.3 v 44.7, p = 0.021). CONCLUSIONS: Neuropsychological abnormalities can be detected early in childhood in apparently normal ex-preterm children and are consistent with a growing body of evidence that prematurity may be associated with long term neuropsychological morbidity in childhood and adolescence.},
affiliation = {IRCCS, Ospedale Pediatrico Bambino Ges{\`u}, Lungomare Guglielmo Marconi 36, I-00058, Santa Marinella, Rome, Italy. bcaravale@libero.it},
number = {6},
pages = {F474--9},
volume = {90},
year = {2005},
month = {Nov},
language = {eng},
keywords = {Prospective Studies, Psychomotor Performance, Infant: Newborn, Cognition, Cognition Disorders, Child Development, Neuropsychological Tests, Infant: Low Birth Weight, Male, Attention, Language Development, Memory, Intelligence, Female, Infant: Premature, Child: Preschool, Humans},
date-added = {2010-02-05 11:44:36 +0100},
date-modified = {2010-02-05 11:44:36 +0100},
doi = {10.1136/adc.2004.070284},
pii = {adc.2004.070284},
pmid = {15956096},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Caravale-2005-Arch%20Dis%20Child%20Fetal%20Neonatal%20Ed_Cognitive%20developmen.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5009},
rating = {0}
}

@article{Chowdhary:2010p12340,
author = {Rajesh Chowdhary and Vladimir B Bajic and Difeng Dong and Limsoon Wong and Jun S Liu},
journal = {BMC Syst Biol},
title = {Genome-wide analysis of regions similar to promoters of histone genes},
abstract = {BACKGROUND : The purpose of this study is to: i) develop a computational model of promoters of human histone-encoding genes (shortly histone genes), an important class of genes that participate in various critical cellular processes, ii) use the model so developed to identify regions across the human genome that have similar structure as promoters of histone genes; such regions could represent potential genomic regulatory regions, e.g. promoters, of genes that may be coregulated with histone genes, and iii/ identify in this way genes that have high likelihood of being coregulated with the histone genes. RESULTS: We successfully developed a histone promoter model using a comprehensive collection of histone genes. Based on leave-one-out cross-validation test, the model produced good prediction accuracy (94.1% sensitivity, 92.6% specificity, and 92.8% positive predictive value). We used this model to predict across the genome a number of genes that shared similar promoter structures with the histone gene promoters. We thus hypothesize that these predicted genes could be coregulated with histone genes. This hypothesis matches well with the available gene expression, gene ontology, and pathways data. Jointly with promoters of the above-mentioned genes, we found a large number of intergenic regions with similar structure as histone promoters. CONCLUSIONS: This study represents one of the most comprehensive computational analyses conducted thus far on a genome-wide scale of promoters of human histone genes. Our analysis suggests a number of other human genes that share a high similarity of promoter structure with the histone genes and thus are highly likely to be coregulated, and consequently coexpressed, with the histone genes. We also found that there are a large number of intergenic regions across the genome with their structures similar to promoters of histone genes. These regions may be promoters of yet unidentified genes, or may represent remote control regions that participate in regulation of histone and histone-coregulated gene transcription initiation. While these hypotheses still remain to be verified, we believe that these form a useful resource for researchers to further explore regulation of human histone genes and human genome. It is worthwhile to note that the regulatory regions of the human genome remain largely un-annotated even today and this study is an attempt to supplement our understanding of histone regulatory regions.},
affiliation = {Department of Statistics, Harvard University, Cambridge, MA 02138, USA. chowdhary@stat.harvard.edu},
pages = {S4},
volume = {4 Suppl 1},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-06-12 10:20:58 +0200},
date-modified = {2010-06-12 10:20:58 +0200},
doi = {10.1186/1752-0509-4-S1-S4},
pii = {1752-0509-4-S1-S4},
pmid = {20522254},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Chowdhary-2010-BMC%20Syst%20Biol_Genome-wide%20analysis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12340},
rating = {0}
}

@misc{Ark:2002,
author = {L Andries van der Ark and B T Hemker and K Sijtsma},
journal = {Miscellaneous},
title = {Hierarchically Related Nonparametric IRT Models, and Practical Data Analysis Methods},
year = {2002},
date-added = {2010-01-10 11:33:18 +0100},
date-modified = {2010-07-29 20:42:55 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Andries%20van%20der%20Ark-2002-Miscellaneous_Hierarchically%20Relat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1968},
rating = {0}
}

@article{MaydeuOlivares:1994p11160,
author = {A Maydeu-Olivares and F Drasgow and A D Mead},
journal = {Applied Psychological Measurement},
title = {Distinguishing among parametric item response models for polytomous ordered data},
number = {3},
pages = {245--256},
volume = {18},
year = {1994},
date-added = {2010-04-25 20:26:49 +0200},
date-modified = {2010-04-25 20:28:10 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Maydeu-Olivares-1994-Applied%20Psychological%20Measurement_Distinguishing%20among.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11160},
rating = {4}
}

@misc{Hastedt:2007,
author = {D Hastedt},
journal = {Miscellaneous},
title = {Differences between multiple-choice and constructed response items in PIRLS 2001},
year = {2007},
date-added = {2010-01-10 11:33:19 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hastedt-2007-Miscellaneous_Differences%20between.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2209},
rating = {0}
}

@article{Skaug:2004p3192,
author = {H J Skaug and D Fournier},
title = {Automatic Approximation of the Marginal Likelihood in Nonlinear Hierarchical Models},
abstract = {We show that the fitting of nonlinear hierarchical random effects models by max- imum likelihood can be made automatic to the same extent that Bayesian model fitting can be automated by the program BUGS. The word `automatic' here means that the technical details of computation are made transparent to the user. We achieve this by combining a technique from computer science known as `automatic differentiation' with the Laplace approximation for calculating the marginal like- lihood. Automatic differentiation, which should not be confused with symbolic differentiation, is mostly unknown to statisticians, and hence we review basic ideas and results. A software prototype that implements our approach has been devel- oped, and the computational performance is reported for a selection of models from the mixed-model literature. In general, our approach performs well in comparison with existing software.},
year = {2004},
date-added = {2010-01-14 20:50:34 +0100},
date-modified = {2010-01-14 20:51:03 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Skaug-2004-_Automatic%20Approximat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3192},
rating = {0}
}

@article{McCabe:2004p5568,
author = {Linda L McCabe and Edward R B McCabe},
journal = {Genet Med},
title = {Direct-to-consumer genetic testing: access and marketing},
affiliation = {Department of Human Genetics and Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.},
number = {1},
pages = {58--9},
volume = {6},
year = {2004},
month = {Jan},
language = {eng},
keywords = {Genetic Counseling, Societies: Medical, Patient Education as Topic, Self Care, Health Services Accessibility, Genetic Testing, Consumer Participation, Marketing of Health Services, Risk Assessment, Organizational Policy, Humans, Health Personnel, Genetic Predisposition to Disease, Physician's Role, United States},
date-added = {2010-02-12 15:34:57 +0100},
date-modified = {2010-02-12 15:34:57 +0100},
doi = {10.1097/01.GIM.0000105753.01536.BE},
pmid = {14726811},
local-url = {file://localhost/Users/chl/Dropbox/Papers/McCabe-2004-Genet%20Med_Direct-to-consumer%20g.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5568},
rating = {0}
}

@article{Sbrana:2005p13038,
author = {Alfredo Sbrana and Jacopo Vittoriano Bizzarri and Paola Rucci and Chiara Gonnelli and Maria Rosa Doria and Sabrina Spagnolli and Laura Ravani and Federica Raimondi and Lilliana Dell'Osso and Giovanni Battista Cassano},
journal = {Compr Psychiatry},
title = {The spectrum of substance use in mood and anxiety disorders},
abstract = {This study evaluates the prevalence of threshold and subthreshold use of substances among patients with psychiatric disorders and 2 comparison groups. Participants were outpatients and inpatients with mood and anxiety disorders, subjects with opiate dependence, and a comparison group of individuals not undergoing treatment for psychiatric disorders. Assessments included the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition , Axis I Disorders, an interview exploring the spectrum of substance use (Structured Clinical Interview for the Spectrum of Substance Use), and a self-report instrument exploring the spectrum of 5 psychiatric disorders (General 5-Spectrum Measure). The overall frequency of substance use disorder (SUD) and that of subthreshold use were 46% and 8% in patients with bipolar disorder, 4% and 26% in those with panic disorder, 8% and 26% in those with obsessive-compulsive disorder, and 6% and 10% in the control group, respectively ( Idouble dagger 2 = 51.6, P < .001). Inspection of standardized residuals indicated that alcohol use disorder and SUD were significantly ( P < .05) more frequent in subjects with bipolar disorder than among those with obsessive-compulsive disorder or panic disorder. The latter showed a significantly higher subthreshold use of substances than control subjects. The pattern of motivations for use varied according to the psychiatric disorder. Our results suggest that the well-established relationship between SUDs and psychiatric disorders might be the end point of a process that starts from increased proneness to substance use, which first leads to self-medication and then may eventually develop into substance abuse or dependence, among subjects with psychiatric symptoms.},
affiliation = {Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, 56127 Pisa, Italy. alfredosbrana@virgilio.it},
number = {1},
pages = {6--13},
volume = {46},
year = {2005},
month = {Jan},
language = {eng},
keywords = {Anxiety Disorders, Substance-Related Disorders, Male, Obsessive-Compulsive Disorder, Diagnostic and Statistical Manual of Mental Disorders, Adult, Female, Interview: Psychological, Ambulatory Care, Middle Aged, Hospitalization, Humans, Panic Disorder, Prevalence, Bipolar Disorder, Adolescent, Mood Disorders},
date-added = {2010-06-25 22:38:48 +0200},
date-modified = {2010-07-29 19:24:13 +0200},
doi = {10.1016/j.comppsych.2004.07.017},
pmid = {15714188},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sbrana-2005-Compr%20Psychiatry_The%20spectrum%20of%20subs.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13038},
rating = {0}
}

@techreport{Antonietti:2003,
author = {J-P Antonietti and N Guignard and A Mudry and L Ntamakiliro and W Rieben and C Ti{\`e}che Christinat and A-C Van der Klink},
journal = {Techreport},
title = {Evaluation des comp{\'e}tences en math{\'e}matiques en fin de 2e ann{\'e}e primaire},
affiliation = {Institut de recherche et de documentation p{\'e}dagogique},
year = {2003},
date-added = {2010-01-10 11:33:20 +0100},
date-modified = {2010-07-29 20:42:07 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Antonietti-2003-Techreport_Evaluation%20des%20comp%C3%A9.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1955},
rating = {0}
}

@article{Brilman:2001,
author = {EI Brilman and J Ormel},
journal = {Psychol Med},
title = {Life events, difficulties and onset of depressive episodes in later life},
abstract = {BACKGROUND: The importance of stressful life events and long-term difficulties in the onset of episodes of unipolar depression is well established for young and middle-aged persons, but less so for older people. METHOD: A prospective case-control study was nested in a large community survey of older people. We recruited 83 onset cases during a 2-year period starting 2 1/2 years after the survey, via screening (N = 59) and GP monitoring (N = 24), and 83 controls, a random sample from the same survey population. We assessed depression with the PSE-10 and life stress exposure with the LEDS. RESULTS: Risk of onset was increased 22-fold by severe events and three-fold by ongoing difficulties of at least moderate severity. Severe events accounted for 21% of all episodes but ongoing difficulties for 45%. The association of onset with life stress, often health-related such as death, major disability and hospitalization of subject or someone close, was most pronounced in the cases identified by screening. While a clear risk threshold for events was found between threat 2 and 3 (on a scale of 1-4), the risk associated with difficulties increased more gradually with severity of difficulty. Compared with controls, severe events involved a larger risk for cases without a prior history of depression (OR = 39.48) than for cases with (OR = 8.86). The opposite was found for mild events (OR = 2.94 in recurrent episodes; OR = 1.09 in first episodes). The impact of ongoing difficulties was independent of severity of episode and history of depression. CONCLUSION: Although the nature of life stress in later life, in particular health-related disability and loss of (close) social contacts, is rather different from that in younger persons, it is a potent risk factor for onset of a depressive episode in old age. Severe events show the largest relative risk, but ongoing difficulties account for most episodes. The association of severe events with onset tends to be stronger in first than in recurrent episodes. Mild events can trigger a recurrent episode but not a first one.},
pages = {859--869},
volume = {31},
year = {2001},
date-added = {2010-01-03 19:36:10 +0100},
date-modified = {2010-01-03 19:36:10 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1080},
rating = {0}
}

@article{Tse:2009p9578,
author = {Ka-Po Tse and Wen-Hui Su and Kai-Ping Chang and Ngan-Ming Tsang and Chia-Jung Yu and Petrus Tang and Lee-Chu See and Chuen Hsueh and Min-Lee Yang and Sheng-Po Hao and Hong-Yi Li and Ming-Hsi Wang and Li-Ping Liao and Lih-Chyang Chen and Sheue-Rong Lin and Timothy J Jorgensen and Yu-Sun Chang and Yin Yao Shugart},
journal = {Am J Hum Genet},
title = {Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3},
abstract = {Nasopharyngeal carcinoma (NPC) is a multifactorial malignancy closely associated with genetic factors and Epstein-Barr virus infection. To identify the common genetic variants linked to NPC susceptibility, we conducted a genome-wide association study (GWAS) in 277 NPC patients and 285 healthy controls within the Taiwanese population, analyzing 480,365 single-nucleotide polymorphisms (SNPs). Twelve statistically significant SNPs were identified and mapped to chromosome 6p21.3. Associations were replicated in two independent sets of case-control samples. Two of the most significant SNPs (rs2517713 and rs2975042; p(combined) = 3.9 x 10(-20) and 1.6 x 10(-19), respectively) were located in the HLA-A gene. Moreover, we detected significant associations between NPC and two genes: specifically, gamma aminobutyric acid b receptor 1 (GABBR1) (rs29232; p(combined) = 8.97 x 10(-17)) and HLA-F (rs3129055 and rs9258122; p(combined) = 7.36 x 10(-11) and 3.33 x 10(-10), respectively). Notably, the association of rs29232 remained significant (residual p < 5 x 10(-4)) after adjustment for age, gender, and HLA-related SNPs. Furthermore, higher GABA(B) receptor 1 expression levels can be found in the tumor cells in comparison to the adjacent epithelial cells (p < 0.001) in NPC biopsies, implying a biological role of GABBR1 in NPC carcinogenesis. To our knowledge, it is the first GWAS report of NPC showing that multiple loci (HLA-A, HLA-F, and GABBR1) within chromosome 6p21.3 are associated with NPC. Although some of these relationships may be attributed to linkage disequilibrium between the loci, the findings clearly provide a fresh direction for the study of NPC development.},
affiliation = {Genomic Medicine Core, Chang Gung Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.},
number = {2},
pages = {194--203},
volume = {85},
year = {2009},
month = {Aug},
language = {eng},
keywords = {Case-Control Studies, Carcinoma, Female, Receptors: GABA-B, Alleles, Histocompatibility Antigens Class I, Male, Immunohistochemistry, Chromosomes: Human: Pair 6, HLA Antigens, Taiwan, Humans, Genome-Wide Association Study, Haplotypes, Nasopharyngeal Neoplasms, Polymorphism: Single Nucleotide, Asian Continental Ancestry Group, Gene Frequency, Linkage Disequilibrium, Cohort Studies},
date-added = {2010-03-24 22:25:11 +0100},
date-modified = {2010-03-24 22:25:11 +0100},
doi = {10.1016/j.ajhg.2009.07.007},
pii = {S0002-9297(09)00298-5},
pmid = {19664746},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Tse-2009-Am%20J%20Hum%20Genet_Genome-wide%20associat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9578},
rating = {0}
}

@article{Kimmel:2006p3352,
author = {Gad Kimmel and Ron Shamir},
journal = {Am J Hum Genet},
title = {A fast method for computing high-significance disease association in large population-based studies},
abstract = {Because of rapid progress in genotyping techniques, many large-scale, genomewide disease-association studies are now under way. Typically, the disorders examined are multifactorial, and, therefore, researchers seeking association must consider interactions among loci and between loci and other factors. One of the challenges of large disease-association studies is obtaining accurate estimates of the significance of discovered associations. The linkage disequilibrium between SNPs makes the tests highly dependent, and dependency worsens when interactions are tested. The standard way of assigning significance (P value) is by a permutation test. Unfortunately, in large studies, it is prohibitively slow to compute low P values by this method. We present here a faster algorithm for accurately calculating low P values in case-control association studies. Unlike with several previous methods, we do not assume a specific distribution of the traits, given the genotypes. Our method is based on importance sampling and on accounting for the decay in linkage disequilibrium along the chromosome. The algorithm is dramatically faster than the standard permutation test. On data sets mimicking medium-to-large association studies, it speeds up computation by a factor of 5,000-100,000, sometimes reducing running times from years to minutes. Thus, our method significantly increases the problem-size range for which accurate, meaningful association results are attainable.},
affiliation = {School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel. kgad@post.tau.ac.il},
number = {3},
pages = {481--92},
volume = {79},
year = {2006},
month = {Sep},
language = {eng},
keywords = {Probability, Case-Control Studies, Genetic Testing, Genetics: Population, Linkage Disequilibrium, Polymorphism: Single Nucleotide, Software, Genetic Predisposition to Disease, Computers, Genotype, Quantitative Trait: Heritable, Humans, Genome: Human, Algorithms},
date-added = {2010-01-15 14:38:53 +0100},
date-modified = {2010-01-15 14:38:53 +0100},
doi = {10.1086/507317},
pii = {S0002-9297(07)62747-5},
pmid = {16909386},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3352},
rating = {0}
}

@article{Ware:1998p5877,
author = {J E Ware and B Gandek and M Kosinski and Neil K Aaronson and G Apolone and J Brazier and M Bullinger and S Kaasa and A Lepl{\`e}ge and L Prieto and M Sullivan and K Thunedborg},
journal = {Journal of Clinical Epidemiology},
title = {The equivalence of SF-36 summary health scores estimated using standard and country-specific algorithms in 10 countries: results from the IQOLA Project. International Quality of Life Assessment},
abstract = {Data from general population surveys (n = 1771 to 9151) in nine European countries (Denmark, France, Germany, Italy, the Netherlands, Norway, Spain, Sweden, and the United Kingdom) were analyzed to test the algorithms used to score physical and mental component summary measures (PCS-36/MCS-36) based on the SF-36 Health Survey. Scoring coefficients for principal components were estimated independently in each country using identical methods of factor extraction and orthogonal rotation. PCS-36 and MCS-36 scores were also estimated using standard (U.S.-derived) scoring algorithms, and results were compared. Product-moment correlations between scores estimated from standard and country-specific scoring coefficients were very high (0.98 to 1.00) for both physical and mental health components in all countries. As hypothesized for orthogonal components, correlations between physical and mental components within each country were very low (0.00 to 0.12) for both estimation methods. Mean scores for PCS-36 differed by as much as 3.0 points across countries using standard scoring, and mean scores for MCS-36 differed across countries by as much as 6.4 points. In view of the high degree of equivalence observed within each country, using standard and country-specific algorithms, we recommend use of standard scoring algorithms for purposes of multinational studies involving these 10 countries.},
affiliation = {Health Assessment Lab at the Health Institute, New England Medical Center, Boston, Massachusetts 02111, USA.},
number = {11},
pages = {1167--70},
volume = {51},
year = {1998},
month = {Nov},
language = {eng},
keywords = {United States, Questionnaires, Europe, Health Status Indicators, Cross-Cultural Comparison, Psychometrics, Quality of Life, Factor Analysis: Statistical, Humans, Algorithms},
date-added = {2010-02-17 15:03:32 +0100},
date-modified = {2010-07-29 20:13:56 +0200},
pii = {S0895435698001085},
pmid = {9817134},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ware-1998-Journal%20of%20Clinical%20Epidemiology_The%20equivalence%20of%20S.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5877},
rating = {0}
}

@article{Besag:2004p6096,
author = {Frank M C Besag},
journal = {Epilepsy Behav},
title = {Behavioral aspects of pediatric epilepsy syndromes},
abstract = {Apart from control of the seizures, two of the most important factors in determining how well a child with epilepsy progresses toward independence are cognition and behavior. The diagnosis of the correct epilepsy syndrome often provides information with regard to probability of good seizure control and intellectual outcome. However, relatively little has been published on the behavioral aspects of the various epilepsy syndromes. In West syndrome there is emerging evidence that early effective treatment might improve outcome in terms of both cognition and behavior. The work on this syndrome in children with tuberous sclerosis has demonstrated an association between temporal lobe tubers and autism. In Dravet syndrome, a variety of psychiatric disorders have been reported, including hyperactivity and autistic features. This is another epilepsy syndrome that tends to be resistant to treatment, implying that the prognosis has to be guarded. The behavioral problems reported with Lennox-Gastaut syndrome also include autistic features, as well as generally sluggish behavior. It is very likely that these characteristics largely reflect the effect of ongoing seizure activity. Autistic features, aggression, and hyperkinesis have been described with Landau-Kleffner syndrome. The behavior may improve dramatically with appropriate medical treatment or after multiple subpial transection. Although the syndrome of benign partial seizures with centrotemporal or rolandic spikes is said to have a very good prognosis, it is becoming increasingly evident that behavioral problems such as concentration difficulties, tempers, hyperactivity, and impulsivity might occur. Juvenile myoclonic epilepsy has been associated with very variable behavioral traits, sometimes with immature personality features and poor social adjustment suggesting frontal lobe dysfunction. Because many of the reports of behavioral disturbance associated with epilepsy syndromes are anecdotal and do not include validated measures of behavior it would be unwise to draw firm conclusions from them at this stage. Carefully conducted prospective studies, paying particular attention to any behavioral improvements that occur with successful treatment of the epilepsy, are required.},
affiliation = {Twinwoods Health Resource Centre, Milton Road, Bedford MK41 6AT, UK. FBesag@aol.com},
pages = {S3--13},
volume = {5 Suppl 1},
year = {2004},
month = {Feb},
language = {eng},
keywords = {Child, Brain, Risk Factors, Neuropsychological Tests, Cerebral Cortex, Child Behavior Disorders, Epilepsy, Prognosis, Cognition Disorders, Syndrome, Humans},
date-added = {2010-02-19 17:05:53 +0100},
date-modified = {2010-02-19 17:05:53 +0100},
pii = {S1525505003003147},
pmid = {14725841},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6096},
rating = {0}
}

@article{vantEnt:2009p4196,
author = {D van 't Ent and C E M van Beijsterveldt and E M Derks and J J Hudziak and D J Veltman and R D Todd and Dorret I Boomsma and E J C de Geus},
journal = {Neuroscience},
title = {Neuroimaging of response interference in twins concordant or discordant for inattention and hyperactivity symptoms},
abstract = {Attention deficit hyperactivity disorder (ADHD) is to a large extent influenced by genetic factors, but environmental influences are considered important as well. To distinguish between functional brain changes underlying primarily genetically and environmentally mediated ADHD, we used functional magnetic resonance imaging (fMRI) to compare response interference in monozygotic twins highly concordant or discordant for attention problems (AP). AP scores were assessed longitudinally with the Child Behavior Check List attention problem scale (CBCL-AP). Response interference was measured during two executive function paradigms; a color-word Stroop and a flanker task. The neuroimaging results indicated that, across the entire sample, children with high CBCL-AP scores, relative to children with low CBCL-AP scores, showed decreased activation to response interference in dorsolateral prefrontal, parietal and temporal brain regions. Increased activation was noted in the premotor cortex and regions associated with visual selective attention processing, possibly reflecting compensatory mechanisms to maintain task performance. Specific comparisons of high and low scoring concordant twin pairs suggest that AP of genetic origin was characterized by decreased activation of the left dorsolateral prefrontal cortex during the Stroop task and right parietal lobe during the flanker task. In contrast, comparison of twins from discordant monozygotic pairs, suggests that AP of environmental origin was characterized by decreased activation in left and right temporal lobe areas, but only during Stroop interference. The finding of distinct brain activation changes to response interference in inattention/hyperactivity of "genetic" versus "environmental" origin, indicates that genetic and environmental risk factors for attention/hyperactivity problems affect the brain in different ways.},
affiliation = {Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands. d.vant.ent@psy.vu.nl},
number = {1},
pages = {16--29},
volume = {164},
year = {2009},
month = {Nov},
language = {eng},
keywords = {Twins, Stroop Test, Environment, Neuropsychological Tests, Psychiatric Status Rating Scales, Genetic Predisposition to Disease, Longitudinal Studies, Magnetic Resonance Imaging, Male, Female, Attention Deficit Disorder with Hyperactivity, Brain, Humans, Adolescent, Brain Mapping, Diseases in Twins, Attention},
date-added = {2010-01-21 07:59:39 +0100},
date-modified = {2010-07-29 20:25:51 +0200},
doi = {10.1016/j.neuroscience.2009.01.056},
pii = {S0306-4522(09)00116-X},
pmid = {19409224},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4196},
rating = {0}
}

@article{Cordell:2005p5293,
author = {Heather J Cordell and David G Clayton},
journal = {Lancet},
title = {Genetic association studies},
abstract = {We review the rationale behind and discuss methods of design and analysis of genetic association studies. There are similarities between genetic association studies and classic epidemiological studies of environmental risk factors but there are also issues that are specific to studies of genetic risk factors such as the use of particular family-based designs, the need to account for different underlying genetic mechanisms, and the effect of population history. Association differs from linkage (covered elsewhere in this series) in that the alleles of interest will be the same across the whole population. As with other types of genetic epidemiological study, issues of design, statistical analysis, and interpretation are very important.},
affiliation = {University of Cambridge, Department of Medical Genetics, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Addenbrookes Hospital, UK. heather.cordell@cimr.cam.ac.uk},
number = {9491},
pages = {1121--31},
volume = {366},
year = {2005},
month = {Jan},
language = {eng},
keywords = {Phenotype, Genetic Predisposition

repository: sergiud/bibtex-spirit

repo_name: sergiud/bibtex-spirit

gha_license_id: MIT