text:
16/j.rmed.2009.01.013},
pii = {S0954-6111(09)00030-4},
pmid = {19217764},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Axelsson-2009-Respir%20Med_Personality%20adheren.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13050},
rating = {0}
}

@article{Moonie:2009p6651,
author = {S Moonie and X Huang and D A Sterling},
journal = {GLOBAL HEALTH GOVERNANCE},
title = {Quality of Life Estimation with Structural Equation Modeling in School Aged Children with Asthma},
abstract = {Significant increases in childhood asthma prevalence and mortality has prompted federal and regulatory agencies to work towards a national framework to address childhood asthma. Quality of life is an important component of chronic disease, and the evaluation of healthcare outcomes. There is little discussion in the literature regarding the implications of QoL as a theoretical construct. This study determined the effect of asthma on the QoL of our study population and caregiver's missed workdays on the child's QoL scores. A negative relationship was found between the child's QoL and the caregiver's missed workdays due to their child's asthma. The use of SEM and multiple group analysis can help increase awareness and understanding among the complex issues related to childhood asthma and quality of life constructs.},
number = {1},
volume = {III},
year = {2009},
date-added = {2010-03-03 20:36:48 +0100},
date-modified = {2010-03-03 20:37:34 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Moonie-2009-GLOBAL%20HEALTH%20GOVERNANCE_Quality%20of%20Life%20Esti.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6651},
rating = {0}
}

@article{Kontodimopoulos:2009p9446,
author = {Nick Kontodimopoulos and Evelina Pappa and Angelos A Papadopoulos and Yannis Tountas and Dimitris Niakas},
journal = {Qual Life Res},
title = {Comparing SF-6D and EQ-5D utilities across groups differing in health status},
abstract = {OBJECTIVES: To compare the EQ-5D and SF-6D within socio-demographic and clinical groups in a representative sample (n = 1,005) of the Greek general population and to examine mean utility differences across groups differing in health in this population and in a highly morbid disease sample (diabetes, n = 215). METHODS: Association and level of agreement between instruments were estimated with Pearson's r and the intraclass correlation coefficient (ICC), respectively. Paired-samples t-test was used to identify significant score differences, which were regarded as minimally important differences (MID) when they exceeded 0.03. The EQ-VAS was used to classify individuals into health status groups, covering the range from very poor to very good health, and the same classification was used in the diabetes sample. RESULTS: EQ-5D and SF-6D were in agreement and strongly correlated over the entire sample (ICC = 0.536, P < 0.001 and r = 0.662, P < 0.001), but correlation varied according to socio-demographic factors and clinical conditions. In healthier responders, EQ-5D scores were significantly higher than SF-6D scores (P < 0.001) and differences constituted MIDs. Contrarily, in individuals with clinical conditions, SF-6D scores were predominantly higher than EQ-5D. The pattern of results was replicated in the disease sample as well. CONCLUSIONS: The hypotheses that EQ-5D generates higher scores in healthier populations and the SF-6D in less healthier groups were confirmed. Based on the evidence provided here, EQ-5D and SF-6D measuring discrepancies generate utility differences across VAS-based health groups, which warrant further within-sample investigation.},
affiliation = {Hellenic Open University, Patras, Greece. nkontodi@otenet.gr},
number = {1},
pages = {87--97},
volume = {18},
year = {2009},
month = {Feb},
language = {eng},
keywords = {Female, Costs and Cost Analysis, Quality of Life, Middle Aged, Adult, Greece, Aged, Humans, Questionnaires, Health Status, Male, Data Interpretation: Statistical, Adolescent, Young Adult},
date-added = {2010-03-23 19:37:37 +0100},
date-modified = {2010-07-29 19:48:30 +0200},
doi = {10.1007/s11136-008-9420-8},
pmid = {19051058},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kontodimopoulos-2009-Qual%20Life%20Res_Comparing%20SF-6D%20and.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9446},
rating = {0}
}

@article{Tanner:1987p6298,
author = {MA Tanner and W H Wong},
journal = {JAMA},
title = {The Calculation of Posterior Distributions by Data Augmentation},
number = {398},
pages = {528--540},
volume = {82},
year = {1987},
date-added = {2010-02-20 20:11:04 +0100},
date-modified = {2010-07-29 20:01:35 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Tanner-1987-JAMA_The%20Calculation%20of%20P.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6298},
rating = {0}
}

@article{Anonymous:2006p12022,
title = {Sparse Kernel Orthonormalized PLS for feature extraction in large data sets},
year = {2006},
date-added = {2010-05-24 10:14:43 +0200},
date-modified = {2010-05-24 10:15:21 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/2006-_Sparse%20Kernel%20Orthon.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12022},
read = {Yes},
rating = {0}
}

@article{Shaffer:2009p7558,
author = {Michele L Shaffer and Allen R Kunselman and Kristi L Watterberg},
journal = {BMC Med Res Methodol},
title = {Analysis of neonatal clinical trials with twin births},
abstract = {BACKGROUND: In neonatal trials of pre-term or low-birth-weight infants, twins may represent 10-20% of the study sample. Mixed-effects models and generalized estimating equations are common approaches for handling correlated continuous or binary data. However, the operating characteristics of these methods for mixes of correlated and independent data are not well established. METHODS: Simulation studies were conducted to compare mixed-effects models and generalized estimating equations to linear regression for continuous outcomes. Similarly, mixed-effects models and generalized estimating equations were compared to ordinary logistic regression for binary outcomes. The parameter of interest is the treatment effect in two-armed clinical trials. Data from the National Institute of Child Health {\&} Human Development Neonatal Research Network are used for illustration. RESULTS: For continuous outcomes, while the coverage never fell below 0.93, and the type I error rate never exceeded 0.07 for any method, overall linear mixed-effects models performed well with respect to median bias, mean squared error, coverage, and median width. For binary outcomes, the coverage never fell below 0.90, and the type I error rate never exceeded 0.07 for any method. In these analyses, when randomization of twins was to the same treatment group or done independently, ordinary logistic regression performed best. When randomization of twins was to opposite treatment arms, a rare method of randomization in this setting, ordinary logistic regression still performed adequately. Overall, generalized linear mixed models showed the poorest coverage values. CONCLUSION: For continuous outcomes, using linear mixed-effects models for analysis is preferred. For binary outcomes, in this setting where the amount of related data is small, but non-negligible, ordinary logistic regression is recommended.},
affiliation = {Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA. mshaffer@hes.hmc.psu.edu},
pages = {12},
volume = {9},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Biometry, Randomized Controlled Trials as Topic, Birth Weight, Analysis of Variance, Twins, Immunoglobulins: Intravenous, Logistic Models, Infant: Newborn, Humans, Algorithms, Bronchopulmonary Dysplasia},
date-added = {2010-03-14 10:55:22 +0100},
date-modified = {2010-03-14 10:55:22 +0100},
doi = {10.1186/1471-2288-9-12},
pii = {1471-2288-9-12},
pmid = {19245713},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Shaffer-2009-BMC%20Med%20Res%20Methodol_Analysis%20of%20neonatal.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7558},
rating = {0}
}

@article{Dupuy2007,
author = {A Dupuy and R M Simon},
journal = {Journal of The National Cancer Institute},
title = {Critical review of published microarray studies for cancer outcome and guidelines on statistical analysis and reporting},
pages = {147--157},
volume = {99},
year = {2007},
date-added = {2010-01-12 14:26:51 +0100},
date-modified = {2010-01-12 14:26:52 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2552},
rating = {0}
}

@article{Bellgrove:2008p3829,
author = {Mark A Bellgrove and Jason B Mattingley},
journal = {Ann N Y Acad Sci},
title = {Molecular genetics of attention},
abstract = {The sequencing of the human genome and the identification of a vast array of DNA polymorphisms has afforded cognitive scientists with the opportunity to interrogate the genetic basis of cognition with renewed vigor. The extant literature on the molecular genetics of sustained and spatial attention is reviewed herein. Advances in our understanding of the neural substrates of sustained and spatial attention arising from the cognitive neurosciences can help guide putative linkages in cognitive genetics. In line with catecholamine models of sustained attention, associations have been reported between sustained attention and allelic variation in the dopamine beta hydroxylase gene (DBH), the dopamine D2 and D4 receptor genes (DRD2; DRD4) and the dopamine transporter gene (DAT1). Much evidence implicates the cholinergic system in spatial attention. Accordingly, individual differences in spatial attention have been associated with variation in an alpha-4 cholinergic receptor gene (CHRNA4). APOE-epsilon4 allele dosage has been shown to influence the speed of attentional reorienting in independent samples of nonaffected individuals. Preliminary evidence in both healthy children and children with attention deficit hyperactivity disorder (ADHD) suggests and association with variants of the DAT1 gene and the control of spatial attention across the hemifields. With the recent development of high-throughput genotyping techniques, such as microarrays, the time seems ripe for a genomewide association study that can identify quantitative trait loci (QTLs) for sustained and spatial attention. The identification of QTLs for attention will provide a range of novel candidate genes for disorders of attention, such as ADHD and schizophrenia, and will drive cognitive neuroscientists to understand how DNA variation influences the neural substrates of attention.},
affiliation = {School of Psychology, University of Queensland, 4072 Queensland, Australia. m.bellgrove@uq.edu.au},
pages = {200--12},
volume = {1129},
year = {2008},
month = {Jan},
language = {eng},
keywords = {Genome: Human, Cognition, Models: Biological, Genetic Predisposition to Disease, Attention, Humans, Molecular Biology},
date-added = {2010-01-16 21:01:57 +0100},
date-modified = {2010-01-16 21:01:57 +0100},
doi = {10.1196/annals.1417.013},
pii = {1129/1/200},
pmid = {18591481},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3829},
rating = {0}
}

@article{Blonigen:2005p9130,
author = {Daniel M Blonigen and Brian M Hicks and Robert F Krueger and Christopher J Patrick and William G Iacono},
journal = {Psychol Med},
title = {Psychopathic personality traits: heritability and genetic overlap with internalizing and externalizing psychopathology},
abstract = {BACKGROUND: Little research has examined genetic and environmental contributions to psychopathic personality traits. Additionally, no studies have examined etiological connections between psychopathic traits and the broad psychopathological domains of internalizing (mood and anxiety) and externalizing (antisocial behavior, substance abuse). The current study was designed to fill these gaps in the literature. METHOD: Participants were 626 pairs of 17-year-old male and female twins from the community. Psychopathic traits were indexed using scores on the Multidimensional Personality Questionnaire (MPQ). Symptoms of internalizing and externalizing psychopathology were obtained via structured clinical interviews. Structural equation modeling was used to estimate genetic and environmental influences on psychopathic personality traits as well as the degree of genetic overlap between these traits and composites of internalizing and externalizing. RESULTS: Twin analyses revealed significant genetic influence on distinct psychopathic traits (Fearless Dominance and Impulsive Antisociality). Moreover, Fearless Dominance was associated with reduced genetic risk for internalizing psychopathology, and Impulsive Antisociality was associated with increased genetic risk for externalizing psychopathology. CONCLUSIONS: These results indicate that different psychopathic traits as measured by the MPQ show distinct genetically based relations with broad dimensions of DSM psychopathology.},
affiliation = {Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455-0344, USA. bloni001@umn.edu},
number = {5},
pages = {637--48},
volume = {35},
year = {2005},
month = {May},
language = {eng},
keywords = {Questionnaires, Humans, Phenotype, Social Environment, Male, Twins, Antisocial Personality Disorder, Female, Adolescent, Impulse Control Disorders},
date-added = {2010-03-22 13:26:38 +0100},
date-modified = {2010-03-22 13:26:38 +0100},
pmid = {15918340},
URL = {http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=15918340&dopt=abstractplus},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Blonigen-2005-Psychol%20Med_Psychopathic%20persona.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9130},
rating = {0}
}

@article{Kleinberg:2004p12860,
author = {J Kleinberg and M Sandler},
journal = {STOC'04},
title = {Using Mixture Models for Collaborative Filtering},
abstract = {A collaborative filtering system at an e-commerce site or similar service uses data about aggregate user behavior to make recommendations tailored to specific user interests. We develop recommendation algorithms with provable per- formance guarantees in a probabilistic mixture model for col- laborative filtering proposed by Hoffman and Puzicha. We identify certain novel parameters of mixture models that are closely connected with the best achievable performance of a recommendation algorithm; we show that for any system in which these parameters are bounded, it is possible to give recommendations whose quality converges to optimal as the amount of data grows.
All our bounds depend on a new measure of independence that can be viewed as an L1-analogue of the smallest sin- gular value of a matrix. Using this, we introduce a tech- nique based on generalized pseudoinverse matrices and lin- ear programming for handling sets of high-dimensional vec- tors. We also show that standard approaches based on L2 spectral methods are not strong enough to yield compara- ble results, thereby suggesting some inherent limitations of spectral analysis.},
year = {2004},
date-added = {2010-06-24 12:37:09 +0200},
date-modified = {2010-06-24 12:37:55 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kleinberg-2004-STOC%E2%80%9904_Using%20Mixture%20Models.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12860},
rating = {0}
}

@article{Martin:2009p5107,
author = {Neilson C Martin and Jan Piek and Grant Baynam and Florence Levy and David Hay},
journal = {Hum Mov Sci},
title = {An examination of the relationship between movement problems and four common developmental disorders},
abstract = {It has been well recognized since the days of "minimal brain dysfunction" (Clements, 1966) that various developmental disorders have a shared aetiology. Poor motor coordination has been implicated as one of the factors in these relationships. This study examines the different patterns in symptomatology of five developmental disorders, namely developmental coordination disorder (DCD), attention-deficit/hyperactivity disorder (ADHD), reading disorder (RD), oppositional defiant disorder (ODD), and conduct disorder (CD) in order to build on the genetic work from Martin, Levy, Piek, and Hay (2006) and Martin, Piek, and Hay (2006) examining the overlap of these disorders. Latent class analysis was used on questionnaire data from 1304 families from the Australian twin ADHD project (ATAP) to examine the patterns of comorbidity of the five disorders. We confirmed and added detail to the shared symptoms between DCD, ADHD, RD, and ODD, but found no links between CD symptoms and any other disorders. Despite the close link previously identified with ODD and CD, this finding suggests a different aetiology for CD.},
affiliation = {Curtin Health Innovation Research Institute, Curtin University of Technology, GPO Box U1987, Perth 6845, Western Australia, Australia.},
pages = {},
year = {2009},
month = {Nov},
language = {ENG},
date-added = {2010-02-05 20:17:20 +0100},
date-modified = {2010-02-05 20:17:20 +0100},
doi = {10.1016/j.humov.2009.09.005},
pii = {S0167-9457(09)00100-6},
pmid = {19944472},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5107},
rating = {0}
}

@article{Lu:2010p9438,
author = {K Lu and L Jiang and A A Tsiatis},
journal = {Biometrics},
title = {Multiple Imputation Approaches for the Analysis of Dichotomized Responses in Longitudinal Studies with Missing Data},
abstract = {Often a binary variable is generated by dichotomizing an underlying continuous variable measured at a specific time point according to a prespecified threshold value. In the event that the underlying continuous measurements are from a longitudinal study, one can use the repeated-measures model to impute missing data on responder status as a result of subject dropout and apply the logistic regression model on the observed or otherwise imputed responder status. Standard Bayesian multiple imputation techniques (Rubin, 1987, in Multiple Imputation for Nonresponse in Surveys) that draw the parameters for the imputation model from the posterior distribution and construct the variance of parameter estimates for the analysis model as a combination of within- and between-imputation variances are found to be conservative. The frequentist multiple imputation approach that fixes the parameters for the imputation model at the maximum likelihood estimates and construct the variance of parameter estimates for the analysis model using the results of Robins and Wang (2000, Biometrika 87, 113--124) is shown to be more efficient. We propose to apply (Kenward and Roger, 1997, Biometrics 53, 983--997) degrees of freedom to account for the uncertainty associated with variance--covariance parameter estimates for the repeated measures model.},
year = {2010},
date-added = {2010-03-23 19:04:02 +0100},
date-modified = {2010-03-23 19:34:06 +0100},
doi = {10.1111/j.1541-0420.2010.01405.x},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Lu-2010-Biometrics_Multiple%20Imputation.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9438},
rating = {0}
}

@article{Janssen:2000p541,
author = {Rianne Janssen and Francis Tuerlinckx and Michel Meulders and Paul De Boeck},
journal = {Journal of Educational and Behavioral Statistics},
title = {A Hierarchical IRT Model for Criterion-Referenced Measurement},
abstract = {A hierarchical IRT model is proposed for mastery classification in criterion- referenced measurement. In this model, items measuring the same criterion are grouped, and a difficulty and discrimination parameter of the criterion is estimated on the same scale as the person and item parameters. The level of proficiency of a student with respect to the criterion is determined by the probability of success on the criterion. Cutoff points on the probability scale can be used to classify respondents into masters and nonmasters. The hierarchical IRT model is estimated using the Gibbs sampler and tested using posterior predictive checks. The model is illustrated with a test measuring the attainment targets of reading comprehension (in Dutch) at the end of primary education.},
affiliation = {University of Leuven},
number = {3},
pages = {285--306},
volume = {25},
year = {2000},
keywords = {hierarchical IRT, Gibbs sampler, posterior predictive checks, criterion-referenced measurement, standard setting},
date-added = {2010-01-03 14:09:08 +0100},
date-modified = {2010-07-29 20:46:12 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Janssen-2000-Journal%20of%20Educational%20and%20Behavioral%20Statistics_A%20Hierarchical%20IRT%20M.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p541},
rating = {0}
}

@article{Horsman:2003p8764,
author = {John Horsman and William Furlong and David Feeny and George Torrance},
journal = {Health Qual Life Outcomes},
title = {The Health Utilities Index (HUI): concepts, measurement properties and applications},
abstract = {This is a review of the Health Utilities Index (HUI) multi-attribute health-status classification systems, and single- and multi-attribute utility scoring systems. HUI refers to both HUI Mark 2 (HUI2) and HUI Mark 3 (HUI3) instruments. The classification systems provide compact but comprehensive frameworks within which to describe health status. The multi-attribute utility functions provide all the information required to calculate single-summary scores of health-related quality of life (HRQL) for each health state defined by the classification systems. The use of HUI in clinical studies for a wide variety of conditions in a large number of countries is illustrated. HUI provides comprehensive, reliable, responsive and valid measures of health status and HRQL for subjects in clinical studies. Utility scores of overall HRQL for patients are also used in cost-utility and cost-effectiveness analyses. Population norm data are available from numerous large general population surveys. The widespread use of HUI facilitates the interpretation of results and permits comparisons of disease and treatment outcomes, and comparisons of long-term sequelae at the local, national and international levels.},
affiliation = {Health Utilities Inc, Dundas, ON, Canada. horsmanj@mcmaster.ca},
pages = {54},
volume = {1},
year = {2003},
month = {Jan},
language = {eng},
keywords = {Quality Assurance: Health Care, Questionnaires, Quality of Life, Quality-Adjusted Life Years, Health Status, Male, Outcome Assessment (Health Care), Psychometrics, Reproducibility of Results, Sickness Impact Profile, Female, Humans},
date-added = {2010-03-22 12:06:37 +0100},
date-modified = {2010-03-22 12:06:37 +0100},
doi = {10.1186/1477-7525-1-54},
pii = {1477-7525-1-54},
pmid = {14613568},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Horsman-2003-Health%20and%20Quality%20of%20Life%20Outcomes_The%20Health%20Utilities.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8764},
rating = {0}
}

@article{Cordell:2004p5291,
author = {Heather J Cordell and Bryan J Barratt and David G Clayton},
journal = {Genet Epidemiol},
title = {Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene-gene and gene-environment interactions, and parent-of-origin effects},
abstract = {Estimation and testing of genetic effects (genotype relative risks) are often performed conditionally on parental genotypes, using data from case-parent trios. This strategy avoids having to estimate nuisance parameters such as parental mating type frequencies, and also avoids generating spurious results due to confounding causes of association such as population stratification. For effects at a single locus, the resulting analysis is equivalent to matched case/control analysis via conditional logistic regression, using the case and three "pseudocontrols" derived from the untransmitted parental alleles. We previously showed that a similar approach can be used for analyzing genotype and haplotype effects at a set of closely linked loci, but with a required adjustment to the conditioning argument that results in varying numbers of pseudocontrols, depending on the disease model that is to be fitted. Here we extend this method to include the analysis of epistatic effects (gene-gene interactions) at unlinked loci, to include parent-of-origin effects at one or more loci, and to allow additional incorporation of gene-environment interactions. The conditional logistic approach provides a natural and flexible framework for incorporating these additional effects. By relaxing the conditioning on parental genotypes to allow exchangeability of parental genotypes, we show how the power of this approach can be increased when studying parent-of-origin effects. Simulations suggest that there is limited power to distinguish between parent-of-origin effects and effects due to interaction between genotypes of mother and child.},
affiliation = {Department of Medical Genetics, University of Cambridge, Cambridge, UK. heather.cordell@cimr.cam.ac.uk},
number = {3},
pages = {167--85},
volume = {26},
year = {2004},
month = {Apr},
language = {eng},
keywords = {Haplotypes, Female, Genotype, Male, Humans, Algorithms, Models: Genetic, Linkage Disequilibrium, Linear Models, Computer Simulation, Pedigree, Logistic Models},
date-added = {2010-02-09 22:29:12 +0100},
date-modified = {2010-02-09 22:29:12 +0100},
doi = {10.1002/gepi.10307},
pmid = {15022205},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5291},
rating = {0}
}

@misc{Lawrence:2000,
author = {E Lawrence and D Bingham and C Liu and V N Nair},
journal = {Miscellaneous},
title = {Bayesian inference for ordinal data using multivariate probit models},
year = {2000},
date-added = {2010-01-10 11:33:22 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Lawrence-2000-Miscellaneous_Bayesian%20inference%20f.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1868},
rating = {0}
}

@article{Shen:2010p5011,
author = {Yijing Shen and Wei Sun and Ker-Chau Li},
journal = {Bioinformatics},
title = {Dynamically weighted clustering with noise set},
abstract = {MOTIVATION: Various clustering methods have been applied to microarray gene expression data for identifying genes with similar expression profiles. As the biological annotation data accumulated, more and more genes have been organized into functional categories. Functionally related genes may be regulated by common cellular signals, thus likely to be co-expressed. Consequently, utilizing the rapidly increasing functional annotation resources such as Gene Ontology (GO) to improve the performance of clustering methods is of great interest. On the opposite side of clustering, there are genes that have distinct expression profiles and do not co-express with other genes. Identification of these scattered genes could enhance the performance of clustering methods. RESULTS: We developed a new clustering algorithm, Dynamically Weighted Clustering with Noise set (DWCN), which makes use of gene annotation information and allows for a set of scattered genes, the noise set, to be left out of the main clusters. We tested the DWCN method and contrasted its results with those obtained using several common clustering techniques on a simulated dataset as well as on two public datasets: the Stanford yeast cell-cycle gene expression data, and a gene expression dataset for a group of genetically different yeast segregants. Conclusion: Our method produces clusters with more consistent functional annotations and more coherent expression patterns than existing clustering techniques. CONTACT: yshen@stat.ucla.edu SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.},
affiliation = {Department of Statistics at University of California, Los Angeles, CA 90095, Department of Biostatistics, Genetics, University of North Carolina, NC 27516, USA and Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, Republic of China.},
number = {3},
pages = {341--7},
volume = {26},
year = {2010},
month = {Feb},
language = {eng},
date-added = {2010-02-05 19:57:01 +0100},
date-modified = {2010-02-05 19:57:01 +0100},
doi = {10.1093/bioinformatics/btp671},
pii = {btp671},
pmid = {20007256},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Shen-2010-Bioinformatics_Dynamically%20weighted.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5011},
rating = {0}
}

@article{Kind:2009p13501,
author = {Paul Kind and Jennifer Elston Lafata and Karl Matuszewski and Dennis Raisch},
journal = {Value Health},
title = {The use of QALYs in clinical and patient decision-making: issues and prospects},
affiliation = {Outcomes Research Group, Centre for Health Economics, Alcuin College, University of York, York, UK. pk1@york.ac.uk},
pages = {S27--30},
volume = {12 Suppl 1},
year = {2009},
month = {Mar},
language = {eng},
keywords = {Resource Allocation, Outcome Assessment (Health Care), Humans, Quality of Life, Health Status, Cost-Benefit Analysis, Decision Making, Quality-Adjusted Life Years},
date-added = {2010-07-07 20:40:15 +0200},
date-modified = {2010-07-07 20:40:15 +0200},
doi = {10.1111/j.1524-4733.2009.00519.x},
pii = {VHE519},
pmid = {19250128},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kind-2009-Value%20Health_The%20use%20of%20QALYs%20in.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13501},
rating = {0}
}

@inproceedings{Thomas:2002a,
author = {D R Thomas and A Cyr},
journal = {Proceedings},
title = {Applying item response theory methods to complex survey data},
year = {2002},
date-added = {2010-01-10 11:33:18 +0100},
date-modified = {2010-07-11 09:27:46 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Thomas-2002-Proceedings_Applying%20item%20respon-2.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2030},
read = {Yes},
rating = {0}
}

@article{Albert:2010p13041,
author = {Umberto Albert and Giuseppe Maina and Filippo Bogetto and Alice Chiarle and David Mataix-Cols},
journal = {Compr Psychiatry},
title = {Clinical predictors of health-related quality of life in obsessive-compulsive disorder},
abstract = {BACKGROUND: Obsessive-compulsive disorder (OCD) is a serious mental disorder that has severe impact on a person's quality of life and those living with a person with OCD. This study systematically examined the clinical variables that are predictive of several domains of quality of life in a large, well-characterized sample of patients attending a specialized treatment unit in Italy. METHODS: The Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) was administered to 151 patients with OCD and their scores were compared to published Italian norms. A principal component analysis was performed on the 13 major categories of the Yale-Brown Obsessive-Compulsive Scale (YBOCS) Symptom Checklist to derive symptom dimension scores. The association between various domains of quality of life and a wide range of clinical variables, including symptom dimension scores, was examined using multiple regression models. RESULTS: Compared to published Italian norms, patients with OCD showed impairment in most domains of quality of life, particularly social functioning. The principal component analysis of the YBOCS Symptom Checklist yielded 5 symptom dimensions that were identical to those previously identified in the international literature. Fewer years of education, higher depression scores (Hamilton Rating Scale for Depression), higher YBOCS obsessions scores, and higher scores on the contamination/washing symptom dimension independently predicted a poorer score on the physical health component of the SF-36. Higher YBOCS compulsions scores, the presence of a current mood disorder, and higher anxiety scores (Hamilton Rating Scale for Anxiety) predicted a poorer score on the mental health component of the SF-36. CONCLUSIONS: Our study confirms that quality of life is severely impaired in patients with OCD. The identification of predictors of quality of life in OCD can help clinicians to adapt their treatment protocols to cater for the individual needs of their patients.},
affiliation = {Mood and Anxiety Disorders Unit, Department of Neurosciences, University of Turin, 10126 Torino, Italy. umberto_albert@hotmail.com},
number = {2},
pages = {193--200},
volume = {51},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-06-26 09:35:16 +0200},
date-modified = {2010-07-29 19:24:13 +0200},
doi = {10.1016/j.comppsych.2009.03.004},
pii = {S0010-440X(09)00044-3},
pmid = {20152302},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Albert-2010-Compr%20Psychiatry_Clinical%20predictors.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13041},
rating = {0}
}

@article{Cohen:1996p4111,
author = {A S Cohen and S H Kim and J A Wollack},
journal = {Applied Psychological Measurement},
title = {An Investigation of the Likelihood Ratio Test For Detection of Differential Item Functioning},
number = {1},
pages = {15--26},
volume = {20},
year = {1996},
date-added = {2010-01-19 23:57:13 +0100},
date-modified = {2010-01-19 23:58:07 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Cohen-1996-Applied%20Psychological%20Measurement_An%20Investigation%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4111},
rating = {0}
}

@article{Dudoit:2000p3404,
author = {S Dudoit and Y H Yang and M J Callow and T P Speed},
title = {Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments},
abstract = {Microarrays are part of a new class of biotechnologies which allow the monitoring of expres- sion levels for thousands of genes simultaneously. This paper describes statistical methods for the identification of differentially expressed genes in replicated cDNA microarray experi- ments. Although it is not the main focus of the paper, we stress the importance of issues such as image processing and normalization. Image processing is required to extract measures of transcript abundance for each gene spotted on the array from the laser scan images. Nor- malization is needed to identify and remove systematic sources of variation, such as differing dye labeling efficiencies and scanning properties. There can be many systematic sources of variation and their effects can be large relative to the effects of interest. After a brief presen- tation of our image processing method, we describe a within-slide normalization approach which handles spatial and intensity dependent effects on the measured expression levels.
Given suitably normalized data, our proposed method for the identification of single differ- entially expressed genes is to consider a univariate testing problem for each gene and then correct for multiple testing using adjusted p-values. No specific parametric form is assumed for the distribution of the expression levels and a permutation procedure is used to esti- mate the joint null distribution of the test statistics for each gene. Several data displays are suggested for the visual identification of genes with altered expression and of important features of these genes. The above methods are applied to microarray data from a study of gene expression in two mouse models with very low HDL cholesterol levels. The genes iden- tified using data from replicated slides are compared to those obtained by applying recently published single-slide methods.},
year = {2000},
date-added = {2010-01-15 14:43:38 +0100},
date-modified = {2010-01-15 14:44:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Dudoit-2000-_Statistical%20methods.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3404},
rating = {0}
}

@article{Turkheimer:2004p7181,
author = {Federico E Turkheimer and John A D Aston and Vincent J Cunningham},
journal = {Eur J Nucl Med Mol Imaging},
title = {On the logic of hypothesis testing in functional imaging},
abstract = {Statistics is nowadays the customary language of functional imaging. It is common to express an experimental setting as a set of null hypotheses over complex models and to present results as maps of p-values derived from sophisticated probability distributions. However, the growing interest in the development of advanced statistical algorithms is not always paralleled by similar attention to how these techniques may regiment the ways in which users draw inferences from their data. This article investigates the logical bases of current statistical approaches in functional imaging and probes their suitability to inductive inference in neuroscience. The frequentist approach to statistical inference is reviewed with attention to its two main constituents: Fisherian "significance testing" and Neyman-Pearson "hypothesis testing". It is shown that these conceptual systems, which are similar in the univariate testing case, dissociate into two quite different methods of inference when applied to the multiple testing problem, the typical framework of functional imaging. This difference is explained with reference to specific issues, like small volume correction, which are most likely to generate confusion in the practitioner. Further insight into this problem is achieved by recasting the multiple comparison problem into a multivariate Bayesian formulation. This formulation introduces a new perspective where the inferential process is more clearly defined in two distinct steps. The first one, inductive in form, uses exploratory techniques to acquire preliminary notions on the spatial patterns and the signal and noise characteristics. The (smaller) set of likely spatial patterns generated is then tested with newer data and a more rigorous multiple hypothesis testing technique (deductive step).},
affiliation = {Department of Neuropathology, Imperial College London, Charing Cross Hospital, St. Dunstan's Road, London, W6 8RP, UK. federico.turkheimer@imperial.ac.uk},
number = {5},
pages = {725--32},
volume = {31},
year = {2004},
month = {May},
language = {eng},
keywords = {Models: Statistical, Evidence-Based Medicine, Algorithms, Diagnostic Imaging, Data Interpretation: Statistical, Models: Biological, Image Interpretation: Computer-Assisted},
date-added = {2010-03-06 20:32:46 +0100},
date-modified = {2010-03-06 20:32:46 +0100},
doi = {10.1007/s00259-003-1387-7},
pmid = {14730402},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7181},
rating = {0}
}

@article{Plomin:2009p7583,
author = {Robert Plomin and Claire M A Haworth},
journal = {Behav Genet},
title = {Genetics of high cognitive abilities},
number = {4},
pages = {347--9},
volume = {39},
year = {2009},
month = {Jul},
language = {eng},
keywords = {Humans, Social Environment, Child, Adolescent, Genotype, Intelligence, Aptitude},
date-added = {2010-03-15 23:09:51 +0100},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-009-9277-9},
pmid = {19430899},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Plomin-2009-Behav%20Genet_Genetics%20of%20high%20cog.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7583},
rating = {0}
}

@manual{Gruijter:2005,
author = {Dato N M de Gruijter and Leo J Th van der Kamp},
journal = {Manual},
title = {Statistical test theory for education and psychology},
year = {2005},
month = {Oct},
date-added = {2010-01-10 11:33:25 +0100},
date-modified = {2010-07-29 19:38:53 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gruijter-2005-Manual_Statistical%20test%20the.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2186},
rating = {0}
}

@article{Fan:2001p7237,
author = {J Fan and Y Wu and J A Fossella and M I Posner},
journal = {BMC Neurosci},
title = {Assessing the heritability of attentional networks},
abstract = {BACKGROUND: Current efforts to study the genetics of higher functions have been lacking appropriate phenotypes to describe cognition. One of the problems is that many cognitive concepts for which there is a single word (e.g. attention) have been shown to be related to several anatomical networks. Recently we have developed an Attention Network Test (ANT) that provides a separate measure for each of three anatomically defined attention networks. In this small scale study, we ran 26 pairs of MZ and DZ twins in an effort to determine if any of these networks show sufficient evidence of heritability to warrant further exploration of their genetic basis. RESULTS: The efficiency of the executive attention network, that mediates stimulus and response conflict, shows sufficient heritability to warrant further study. Alerting and overall reaction time show some evidence for heritability and in our study the orienting network shows no evidence of heritability. CONCLUSIONS: These results suggest that genetic variation contributes to normal individual differences in higher order executive attention involving dopamine rich frontal areas including the anterior cingulate. At least the executive portion of the ANT may serve as a valid endophenotype for larger twin studies and subsequent molecular genetic analysis in normal subject populations.},
affiliation = {Sackler Institute, Weill Medical College, Cornell University, New York, USA. jif2004@med.cornell.edu},
pages = {14},
volume = {2},
year = {2001},
month = {Jan},
language = {eng},
keywords = {Humans, Neurophysiology, Female, Twins: Monozygotic, Gyrus Cinguli, Attention, Male, Twins: Dizygotic, Adolescent, Cognition, Adult, Genetic Variation, Frontal Lobe, Nerve Net, Reaction Time, Orientation},
date-added = {2010-03-08 20:22:11 +0100},
date-modified = {2010-03-08 20:22:11 +0100},
pmid = {11580865},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fan-2001-BMC%20Neurosci_Assessing%20the%20herita.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7237},
rating = {0}
}

@article{Pober:2001,
author = {JS Pober and CS Neuhauser and JM Pober},
journal = {The FASEB Journal},
title = {Obstacles facing translational research in academic medical centers},
abstract = {Over the last quarter of the 20th century, there has been a boom in biomedical research discoveries that, for the most part, has not been successfully exploited for improving medical therapy or diagnosis. This lack of success is surprising because there is a broad consensus within academic medical centers (AMCs) that a primary mission is to move scientific discoveries into meaningful clinical outcomes, and there are numerous opportunities for doing so. We illustrate the latter point with 10 clinical opportunities for translating scientific discoveries from our field of vascular biology and transplantation. We attribute the limited success of translation to various factors, chief of which is that translation is rarely straightforward and requires continuing research in both the clinic and the laboratory. Translational research is hindered by insufficient targeted resources, a shortage of qualified investigators, an academic culture that hinders collaboration between clinical and laboratory-based investigators, a traditional structure of the AMC that favors departmental efforts over interdisciplinary programs, an increasing regulatory burden, and a lack of specific mechanisms within the AMC for facilitating solutions to these problems. We offer several suggestions to reduce these impediments.---Pober, J. S., Neuhauser, C. S., Pober, J. M. Obstacles facing translational research in academic medical centers.},
number = {13},
pages = {2303--2313},
volume = {15},
year = {2001},
date-added = {2010-01-03 19:34:17 +0100},
date-modified = {2010-01-03 19:34:18 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1006},
rating = {0}
}

@article{Samejima:1975p11155,
author = {F Samejima},
title = {Graded response model of the latent trait theory and tailored testing},
year = {1975},
date-added = {2010-04-25 19:23:02 +0200},
date-modified = {2010-04-25 19:23:50 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Samejima-1975-_Graded%20response%20mode.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11155},
rating = {0}
}

@article{AbdElFattah:2007p11579,
author = {S M Abd-El-Fattah},
journal = {International Education Journal},
title = {Is the Aggression Questionnaire bias free? A Rasch analysis},
abstract = {Buss and Perry (1992) developed the Aggression Questionnaire (AQ) to assess aggressiveness as a personality trait in high school and college samples. The AQ has been used by researchers in United States, Italy, Germany, Netherland, Japan, Canada, and Greece. The present study is reported on an Arabic adapted version of the AQ among a sample of 510 Egyptian high school students. An exploratory factor analysis technique defined four factors: physical aggression (9 items), verbal aggression (5 items), anger (7 items), and hostility (8 items). The correlation among the four factors ranged from 0.38 to 0.49. A confirmatory factor analysis revealed that the AQ could be described by four first levels factors that were linked by a higher order factor of general aggression. Rasch analysis showed that the AQ was bias free. Relevance of these findings to the assessment of the trait aggressiveness is discussed.},
number = {2},
pages = {237--248},
volume = {8},
year = {2007},
date-added = {2010-05-09 18:23:59 +0200},
date-modified = {2010-05-23 22:43:10 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Abd-El-Fattah-2007-International%20Education%20Journal_Is%20the%20Aggression%20Qu.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11579},
rating = {4}
}

@article{Fava:2005p7470,
author = {Giovanni A Fava and Carlotta Belaise},
journal = {Journal of Clinical Epidemiology},
title = {A discussion on the role of clinimetrics and the misleading effects of psychometric theory},
abstract = {BACKGROUND: Psychometric theory is the basis for the development of assessment instruments in psychiatric research. METHODS: It has produced a number of variable methods for improving the validity and reliability of clinical assessment. However, the psychometric model appears to be largely inadequate in the clinical setting because of its lack of sensitivity to change and its quest for homogeneous components. RESULTS: Clinimetrics offers a viable integration to psychometrics, both from a conceptual and a methodologic viewpoint. CONCLUSION: Without such integration, psychometric rules and methods may lead to misleading effects in clinical research both in psychiatry and medicine.},
affiliation = {Department of Psychology, University of Bologna, viale Berti Pichat 5, 40127 Bologna, Italy. giovanniandrea.fava@unibo.it},
number = {8},
pages = {753--6},
volume = {58},
year = {2005},
month = {Aug},
language = {eng},
keywords = {Medical Informatics, Psychiatric Status Rating Scales, Humans, Mental Disorders, Psychometrics},
date-added = {2010-03-10 20:43:08 +0100},
date-modified = {2010-03-10 20:43:13 +0100},
doi = {10.1016/j.jclinepi.2004.12.006},
pii = {S0895-4356(05)00084-3},
pmid = {16018909},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fava-2005-Journal%20of%20Clinical%20Epidemiology_A%20discussion%20on%20the.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7470},
rating = {3}
}

@article{Friedman:2008p4936,
author = {J H Friedman},
title = {Fast sparse regression and classification},
year = {2008},
date-added = {2010-02-03 11:44:27 +0100},
date-modified = {2010-02-03 11:45:24 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Friedman-2008-_Fast%20sparse%20regressi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4936},
rating = {0}
}

@article{Strohle:2008p9590,
author = {Andreas Str{\"o}hle and Meline Stoy and Jana Wrase and Steffi Schwarzer and Florian Schlagenhauf and Michael Huss and Jakob Hein and Anke Nedderhut and Britta Neumann and Andreas Gregor and Georg Juckel and Brian Knutson and Ulrike Lehmkuhl and Michael Bauer and Andreas Heinz},
journal = {Neuroimage},
title = {Reward anticipation and outcomes in adult males with attention-deficit/hyperactivity disorder},
abstract = {Attention-deficit/hyperactivity disorder (ADHD) has been suggested to involve deficits in reward processing. We used functional magnetic resonance imaging (fMRI) to compare the neural responses to reward anticipation and outcomes in 10 adults with ADHD and 10 controls as they played a monetary incentive delay task. Adults with ADHD were unmedicated, and groups were matched for age, verbal IQ and smoking habits. Adults with ADHD showed decreased activation in the ventral striatum during the anticipation of gain, but increased activation of the orbitofrontal cortex in response to gain outcomes. Ventral striatal activation in adults with ADHD during gain anticipation was negatively correlated with self-rated symptoms of hyperactivity and impulsivity. These findings suggest that male adults with ADHD show neural signs of abnormal reward processing. Future studies will have to investigate whether these dysfunctional patterns might be normalized by treatment.},
affiliation = {Department of Psychiatry and Psychotherapy, Campus Charit{\'e} Mitte, Charit{\'e}-Universit{\"a}tsmedizin Berlin, Schumannstr. 20/21, 10117 Berlin, Germany. andreas.stroehle@charite.de},
note = {genim},
number = {3},
pages = {966--72},
volume = {39},
year = {2008},
month = {Feb},
language = {eng},
keywords = {Reward, Psychiatric Status Rating Scales, Neostriatum, Prefrontal Cortex, Humans, Male, Motivation, Data Interpretation: Statistical, Adult, Neuropsychological Tests, Attention Deficit Disorder with Hyperactivity},
date-added = {2010-03-25 14:33:26 +0100},
date-modified = {2010-03-25 18:15:47 +0100},
doi = {10.1016/j.neuroimage.2007.09.044},
pii = {S1053-8119(07)00842-7},
pmid = {17996464},
URL = {http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-4PTMXTM-3&_user=2432700&_coverDate=02%252F01%252F2008&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000057263&_version=1&_urlVersion=0&_userid=2432700&md5=5e09c45c8c36f3e79c3f906076431950},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Str%C3%B6hle-2008-Neuroimage_Reward%20anticipation.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9590},
rating = {0}
}

@article{Mitchell:2005p2324,
author = {M N Mitchell},
journal = {Statistical Consulting Group: UCLA Academic Technology Services},
title = {Strategically using General Purpose Statistics Packages: A Look at Stata, SAS and SPSS},
year = {2005},
date-added = {2010-01-10 12:50:08 +0100},
date-modified = {2010-01-10 12:50:51 +0100},
URL = {http://www.ats.ucla.edu/stat/technicalreports/},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mitchell-2005-Statistical%20Consulting%20Group%20UCLA%20Academic%20Technology%20Services_Strategically%20using.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2324},
rating = {0}
}

@article{Silverstein:2010p1695,
author = {J W Silverstein and Z D Bai},
title = {On the Empirical Distribution of Eigenvalues of a Class of Large Dimensional Random Matrices},
date-added = {2010-01-09 18:50:20 +0100},
date-modified = {2010-01-09 18:51:20 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Silverstein--_On%20the%20Empirical%20Dis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1695},
rating = {0}
}

@article{Amin:2004p10205,
author = {Z Amin and R T Constable and T Canli},
journal = {Journal of Research in Personality},
title = {Attentional bias for valenced stimuli as a function of personality in the dot-probe task},
abstract = {Extroversion (E) and neuroticism (N) are associated with positive and negative affect, re- spectively. This correspondence between each dimension of personality with each dimension of affect may reflect a common mechanism, such as attentional bias to emotional stimuli. We used functional magnetic resonance imaging (fMRI) while participants were engaged in an attentional task to identify brain regions that may be involved in attentional bias as a func- tion of E or N. By adapting, for the first time, the dot-probe attentional task for use in the scanner, we discovered that activation in the fusiform gyrus is significantly correlated with E. The greatest activation was observed in conditions in which an attentional probe was placed in a section of the visual field least likely to be attended to by highly extroverted individuals. This activation may reflect increased effort related to visual search, autonomic arousal, or detection of an unexpected occurrence.},
pages = {15--23},
volume = {38},
year = {2004},
date-added = {2010-04-01 18:18:37 +0200},
date-modified = {2010-07-29 19:36:11 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Amin-2004-Journal%20of%20Research%20in%20Personality_Attentional%20bias%20for.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10205},
rating = {0}
}

@article{Carey:2009p522,
author = {V J Carey and R Gentleman},
journal = {Pac Symp Biocomput},
title = {Interpreting genetics of gene expression: Integrative architecture in Bioconductor},
abstract = {Several influential studies of genotypic determinants of gene expression in humans have now been published based on various populations including HapMap cohorts. The magnitude of the analytic task (transcriptome vs. SNP-genome) is a hindrance to dissemination of efficient, thorough, and auditable inference methods for this project. We describe the structure and use of Bioconductor facilities for inference in genetics of gene expression, with simultaneous application to multiple HapMap cohorts. Tools distributed for this purpose are readily adapted for the structure and analysis of privately-generated data in expression genetics.},
pages = {380--390},
volume = {14},
year = {2009},
date-added = {2010-01-03 13:34:05 +0100},
date-modified = {2010-07-29 19:42:21 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Carey-2009-Pac%20Symp%20Biocomput_Interpreting%20genetic.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p522},
read = {Yes},
rating = {0}
}

@article{Mahata:2006p1615,
author = {P Mahata and W Costa and C Cotta and P Moscato},
title = {Hierarchical Clustering, Languages and Cancer},
abstract = {In this paper, we introduce a novel objective function for the hierarchical clustering of data from distance matrices, a very relevant task in Bioinformatics. To test the robustness of the method, we test it in two areas: (a) the problem of deriving a phylogeny of languages and (b) subtype cancer classification from microarray data. For comparison purposes, we also consider both the use of ultrametric trees (generated via a two-phase evolutionary approach that creates a large number of hypothesis trees, and then takes a consensus), and the best-known results from the literature.
We used a dataset of measured 'separation time' among 84 Indo-European languages. The hierarchy we produce agrees very well with existing data about these languages across a wide range of levels, and it helps to clarify and raise new hypothesis about the evolution of these languages.
Our method also generated a classification tree for the different cancers in the NCI60 microarray dataset (comprising gene expression data for 60 cancer cell lines). In this case, the method seems to support the cur- rent belief about the heterogeneous nature of the ovarian, breast and non-small-lung cancer, as opposed to the relative homogeneity of other types of cancer. However, our method reveals a close relationship of the melanoma and CNS cell-lines. This is in correspondence with the fact that metastatic melanoma first appears in central nervous system (CNS).},
affiliation = {Newcastle Bioinformatics Initiative, School of Electrical Engineering and Computer Science, The University of Newcastle, Callaghan, NSW, 2308, Australia},
year = {2006},
date-added = {2010-01-07 17:15:02 +0100},
date-modified = {2010-01-07 17:16:02 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mahata-2006-_Hierarchical%20Cluster.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1615},
rating = {0}
}

@article{Imai:2008p3598,
author = {K Imai and G King and O Lau},
journal = {Journal of Computational and Graphical Statistics},
title = {Toward A Common Framework for Statistical Analysis and Development},
abstract = {We develop a general ontology of statistical methods and use it to propose a com- mon framework for statistical analysis and software development built on and within the R language, including R's numerous existing packages. This framework offers a simple unified structure and syntax that can encompass a large fraction of existing sta- tistical procedures. We conjecture that it can be used to encompass and present simply a vast majority of existing statistical methods, without requiring changes in existing approaches, and regardless of the theory of inference on which they are based, notation with which they were developed, and programming syntax with which they have been implemented. This development enabled us, and should enable others, to design statis- tical software with a single, simple, and unified user interface that helps overcome the conflicting notation, syntax, jargon, and statistical methods existing across the methods subfields of numerous academic disciplines. The approach also enables one to build a graphical user interface that automatically includes any method encompassed within the framework. We hope that the result of this line of research will greatly reduce the time from the creation of a new statistical innovation to its widespread use by applied researchers whether or not they use or program in R.},
number = {4},
pages = {1--22},
volume = {17},
year = {2008},
date-added = {2010-01-15 21:30:02 +0100},
date-modified = {2010-01-15 21:30:53 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Imai-2008-Journal%20of%20Computational%20and%20Graphical%20Statistics_Toward%20A%20Common%20Fram.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3598},
rating = {0}
}

@article{Neeleman:1998,
author = {J Neeleman},
journal = {Int J Epidemiol},
title = {Regional suicide rates in the Netherlands: does religion still play a role?},
abstract = {BACKGROUND: This study examined the nature of ecological associations between `religiousness' and suicide rates (1985--1994) in the 11 provinces in the Netherlands. METHODS: indices of religiousness, obtained from a nationwide survey, were used as aggreg ate predictors of provincial suicide rates in weighted linear regressions, and as individual-level predictors of suicide acceptance in logistic regressions. Socio demographic confounding was controlled for. RESULTS: Orthodox beliefs and religious affiliation were the best predictors of lower suicide acceptance in individuals and of lower suicide rates in provinces. The ecological association was most pronounced in the least religious parts of the country givingrise to a curvilinear ecological regression line. CONCLUSIONS: Curvilinear ecological regression lines arise when mean levels of exposure affect individual risk above and beyond personal exposure i.e. when there is ecological effect modification. This study demonstrates that such contextual effects, respons ible for cross-level bias, apply to the association between suicide and religious ness. Variation, from context to context, of the effects of exposure to psychosocial risk or protective factors for outcomes such as suicide, has important implications for research and prevention.},
pages = {466--472},
volume = {27},
year = {1998},
date-added = {2010-01-03 19:36:09 +0100},
date-modified = {2010-01-03 19:36:10 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1093},
rating = {0}
}

@article{Fayers:1998p6832,
author = {P M Fayers and M Groenvold and D J Hand and K Bjordal},
journal = {Journal of Clinical Epidemiology},
title = {Clinical impact versus factor analysis for quality of life questionnaire construction},
number = {3},
pages = {285--6},
volume = {51},
year = {1998},
month = {Mar},
language = {eng},
keywords = {Factor Analysis: Statistical, Humans, Research Design, Questionnaires, Quality of Life},
date-added = {2010-03-06 10:29:35 +0100},
date-modified = {2010-03-06 10:29:35 +0100},
pii = {S0895435697002916},
pmid = {9495694},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6832},
rating = {0}
}

@article{Dolan:2009p13783,
author = {C V Dolan and F J Oort and R D Stoel and J M Wicherts},
journal = {Structural Equation Modeling},
title = {Testing Measurement Invariance in the Target Rotated Multigroup
Exploratory Factor Model},
abstract = {We propose a method to investigate measurement invariance in the multigroup exploratory factor model, subject to target rotation. We consider both oblique and orthogonal target rotation. This method has clear advantages over other approaches, such as the use of congruence measures. We demonstrate that the model can be implemented readily in the freely available Mx program. We present the results of 2 illustrative analyses, one based on artificial data, and the other on real data relating to personality in male and female psychology students.},
pages = {295--314},
volume = {16},
year = {2009},
date-added = {2010-07-29 12:13:17 +0200},
date-modified = {2010-07-29 19:51:13 +0200},
doi = {10.1080/10705510902751416},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Dolan-2009-Structural%20Equation%20Modeling_Testing%20Measurement.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13783},
rating = {0}
}

@article{Veerkamp:2000,
author = {W Veerkamp and C A W Glas},
journal = {Journal of Behavioral and Educational Statistics},
title = {Detection of known items in adaptive testing with a statistical quality control method},
pages = {373--389},
volume = {25},
year = {2000},
date-added = {2010-01-10 11:33:18 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Veerkamp-2000-Journal%20of%20Behavioral%20and%20Educational%20Statistics_Detection%20of%20known%20i.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2196},
rating = {0}
}

@article{AmbesiImpiombato:2006p11868,
author = {Alberto Ambesi-Impiombato and Mukesh Bansal and Pietro Li{\`o} and Diego di Bernardo},
journal = {BMC Neurosci},
title = {Computational framework for the prediction of transcription factor binding sites by multiple data integration},
abstract = {Control of gene expression is essential to the establishment and maintenance of all cell types, and its dysregulation is involved in pathogenesis of several diseases. Accurate computational predictions of transcription factor regulation may thus help in understanding complex diseases, including mental disorders in which dysregulation of neural gene expression is thought to play a key role. However, biological mechanisms underlying the regulation of gene expression are not completely understood, and predictions via bioinformatics tools are typically poorly specific. We developed a bioinformatics workflow for the prediction of transcription factor binding sites from several independent datasets. We show the advantages of integrating information based on evolutionary conservation and gene expression, when tackling the problem of binding site prediction. Consistent results were obtained on a large simulated dataset consisting of 13050 in silico promoter sequences, on a set of 161 human gene promoters for which binding sites are known, and on a smaller set of promoters of Myc target genes. Our computational framework for binding site prediction can integrate multiple sources of data, and its performance was tested on different datasets. Our results show that integrating information from multiple data sources, such as genomic sequence of genes' promoters, conservation over multiple species, and gene expression data, indeed improves the accuracy of computational predictions.},
affiliation = {TIGEM, Telethon Institute of Genetics and Medicine, Naples, Italy. ambesi@unina.it},
pages = {S8},
volume = {7 Suppl 1},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Transcription Factors, Humans, Gene Expression Regulation, Binding Sites, Computer Simulation, Animals, Databases: Genetic, Predictive Value of Tests, Computational Biology, Protein Binding, Neural Networks (Computer)},
date-added = {2010-05-23 11:51:27 +0200},
date-modified = {2010-05-23 11:51:27 +0200},
doi = {10.1186/1471-2202-7-S1-S8},
pii = {1471-2202-7-S1-S8},
pmid = {17118162},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11868},
rating = {0}
}

@article{Spencer:2009p3191,
author = {Chris C A Spencer and Zhan Su and Peter Donnelly and Jonathan Marchini},
journal = {PLoS Genet},
title = {Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip},
abstract = {Genome-wide association studies are revolutionizing the search for the genes underlying human complex diseases. The main decisions to be made at the design stage of these studies are the choice of the commercial genotyping chip to be used and the numbers of case and control samples to be genotyped. The most common method of comparing different chips is using a measure of coverage, but this fails to properly account for the effects of sample size, the genetic model of the disease, and linkage disequilibrium between SNPs. In this paper, we argue that the statistical power to detect a causative variant should be the major criterion in study design. Because of the complicated pattern of linkage disequilibrium (LD) in the human genome, power cannot be calculated analytically and must instead be assessed by simulation. We describe in detail a method of simulating case-control samples at a set of linked SNPs that replicates the patterns of LD in human populations, and we used it to assess power for a comprehensive set of available genotyping chips. Our results allow us to compare the performance of the chips to detect variants with different effect sizes and allele frequencies, look at how power changes with sample size in different populations or when using multi-marker tags and genotype imputation approaches, and how performance compares to a hypothetical chip that contains every SNP in HapMap. A main conclusion of this study is that marked differences in genome coverage may not translate into appreciable differences in power and that, when taking budgetary considerations into account, the most powerful design may not always correspond to the chip with the highest coverage. We also show that genotype imputation can be used to boost the power of many chips up to the level obtained from a hypothetical "complete" chip containing all the SNPs in HapMap. Our results have been encapsulated into an R software package that allows users to design future association studies and our methods provide a framework with which new chip sets can be evaluated.},
affiliation = {Department of Statistics, University of Oxford, Oxford, United Kingdom.},
number = {5},
pages = {e1000477},
volume = {5},
year = {2009},
month = {May},
language = {eng},
keywords = {Sample Size, Humans, Software, Polymorphism: Single Nucleotide, Linkage Disequilibrium, Genotype, Genome-Wide Association Study, Genome: Human},
date-added = {2010-01-14 20:49:50 +0100},
date-modified = {2010-01-14 20:49:50 +0100},
doi = {10.1371/journal.pgen.1000477},
pmid = {19492015},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Spencer-2009-PLoS%20Genet_Designing%20genome-wid.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3191},
rating = {0}
}

@article{Sintonen:1994p8455,
author = {H Sintonen},
title = {The 15-D Measure of Health Related Quality of Life: Reliability, Validity and Sensitivity of its Health State Descriptive System},
year = {1994},
date-added = {2010-03-21 17:57:54 +0100},
date-modified = {2010-03-21 17:58:19 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sintonen-1994-_The%2015-D%20Measure%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8455},
rating = {0}
}

@article{McDonald:1982p2703,
author = {R P McDonald},
journal = {Applied Psychological Measurement},
title = {Linear Versus Models in Item Response Theory},
number = {4},
pages = {379--396},
volume = {6},
year = {1982},
date-added = {2010-01-13 10:21:58 +0100},
date-modified = {2010-07-29 19:16:54 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/McDonald-1982-Applied%20Psychological%20Measurement_Linear%20Versus%20Models.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2703},
rating = {0}
}

@article{Crandall:2008p2801,
author = {R Crandall and J Klivington and D Mitchell},
title = {Large-scale FFTs and convolutions on Apple hardware},
abstract = {Impressive FFT performance for large signal lengths can be achieved via a matrix paradigm that exploits the modern concepts of cache, memory, and multicore/multithreading. Each of the large-scale FFT implementations we report herein is built hierarchically on very fast FFTs from the standard OS X Accelerate library. (The hierarchical ideas should apply equally well for low-level FFTs of, say, the OpenCL/GPU variety.) By building on such established, packaged, small-length FFTs, one can achieve on a single Apple machine---and even for signal lengths into the billions---sustained processing rates in the multi-gigaflop/s region.},
affiliation = {Advanced Computation Group, Apple Inc.},
year = {2008},
date-added = {2010-01-13 14:30:49 +0100},
date-modified = {2010-01-13 14:31:26 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Crandall-2008-_Large-scale%20FFTs%20and.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2801},
rating = {0}
}

@article{Reif:2009p8928,
author = {Andreas Reif and Christian P Jacob and Dan Rujescu and Sabine Herterich and Sebastian Lang and Lise Gutknecht and Christina G Baehne and Alexander Strobel and Christine M Freitag and Ina Giegling and Marcel Romanos and Annette Hartmann and Michael R{\"o}sler and Tobias J Renner and Andreas J Fallgatter and Wolfgang Retz and Ann-Christine Ehlis and Klaus-Peter Lesch},
journal = {Arch Gen Psychiatry},
title = {Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans},
abstract = {CONTEXT: Human personality is characterized by substantial heritability but few functional gene variants have been identified. Although rodent data suggest that the neuronal isoform of nitric oxide synthase (NOS-I) modifies diverse behaviors including aggression, this has not been translated to human studies. OBJECTIVES: To investigate the functionality of an NOS1 promoter repeat length variation (NOS1 Ex1f variable number tandem repeat [VNTR]) and to test whether it is associated with phenotypes relevant to impulsivity. DESIGN: Molecular biological studies assessed the cellular consequences of NOS1 Ex1f VNTR; association studies were conducted to investigate the impact of this genetic variant on impulsivity; imaging genetics was applied to determine whether the polymorphism is functional on a neurobiological level. SETTING: Three psychiatric university clinics in Germany. PARTICIPANTS: More than 3200 subjects were included in the association study: 1954 controls, 403 patients with personality disorder, 383 patients with adult attention-deficit/hyperactivity disorder (ADHD), 151 with familial ADHD, 189 suicide attempters, and 182 criminal offenders. MAIN OUTCOME MEASURES: For the association studies, the major outcome criteria were phenotypes relevant to impulsivity, namely, the dimensional phenotype conscientiousness and the categorical phenotypes adult ADHD, aggression, and cluster B personality disorder. RESULTS: A novel functional promoter polymorphism in NOS1 was associated with traits related to impulsivity, including hyperactive and aggressive behaviors. Specifically, the short repeat variant was more frequent in adult ADHD, cluster B personality disorder, and autoaggressive and heteroaggressive behavior. This short variant came along with decreased transcriptional activity of the NOS1 exon 1f promoter and alterations in the neuronal transcriptome including RGS4 and GRIN1. On a systems level, it was associated with hypoactivation of the anterior cingulate cortex, which is involved in the processing of emotion and reward in behavioral control. CONCLUSION: These findings implicate deficits in neuronal signaling via nitric oxide in moderation of prefrontal circuits underlying impulsivity-related behavior in humans.},
affiliation = {Department of Psychiatry, Psychosomatics and Psychotherapy, University of W{\"u}rzburg, F{\"u}chsleinstr 15, D-97080 W{\"u}rzburg, Germany. reif_a@klinik.uni-wuerzburg.de},
number = {1},
pages = {41--50},
volume = {66},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Phenotype, Gene Expression Profiling, Attention, Young Adult, Personality Disorders, Prisoners, Electroencephalography, Promoter Regions: Genetic, Adult, Alleles, Middle Aged, Aggression, Neurons, Psychomotor Performance, Prefrontal Cortex, Impulsive Behavior, Suicide: Attempted, Genetic Variation, Male, Humans, Adolescent, Nitric Oxide Synthase Type I, Minisatellite Repeats, Female, Neuropsychological Tests, Event-Related Potentials: P300, Reference Values, Genotype, Attention Deficit Disorder with Hyperactivity, Violence, Child},
date-added = {2010-03-22 13:04:45 +0100},
date-modified = {2010-03-22 13:04:46 +0100},
doi = {10.1001/archgenpsychiatry.2008.510},
pii = {66/1/41},
pmid = {19124687},
URL = {http://archpsyc.ama-assn.org/cgi/content/full/66/1/41},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Reif-2009-Arch%20Gen%20Psychiatry_Influence%20of%20functio.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8928},
rating = {0}
}

@article{Smit:2010p7653,
author = {D J A Smit and M Boersma and C E M van Beijsterveldt and D Posthuma and Dorret I Boomsma and C J Stam and E J C de Geus},
journal = {Behav Genet},
title = {Endophenotypes in a dynamically connected brain},
abstract = {We examined the longitudinal genetic architecture of three parameters of functional brain connectivity. One parameter described overall connectivity (synchronization likelihood, SL). The two others were derived from graph theory and described local (clustering coefficient, CC) and global (average path length, L) aspects of connectivity. We measured resting state EEG in 1,438 subjects from four age groups of about 16, 18, 25 and 50 years. Developmental curves for SL and L indicate that connectivity is more random at adolescence and old age, and more structured in middle-aged adulthood. Individual variation in SL and L were moderately to highly heritable at each age (SL: 40-82%; L: 29-63%). Genetic factors underlying these phenotypes overlapped. CC was also heritable (25-49%) but showed no systematic overlap with SL and L. SL, CC, and L in the alpha band showed high phenotypic and genetic stability from 16 to 25 years. Heritability for parameters in the beta band was lower, and less stable across ages, but genetic stability was high. We conclude that the connectivity parameters SL, CC, and L in the alpha band show the hallmarks of a good endophenotype for behavior and developmental disorders.},
affiliation = {Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands. dja.smit@psy.vu.nl},
number = {2},
pages = {167--77},
volume = {40},
year = {2010},
month = {Mar},
language = {eng},
date-added = {2010-03-15 23:21:36 +0100},
date-modified = {2010-07-29 20:25:51 +0200},
doi = {10.1007/s10519-009-9330-8},
pmid = {20111993},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Smit-2010-Behav%20Genet_Endophenotypes%20in%20a.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7653},
read = {Yes},
rating = {4}
}

@book{Diggle:2002,
author = {P J Diggle and P Heagerty and K-Y Liang and S L Zeger},
journal = {Book},
title = {Analysis of longitudinal data},
year = {2002},
date-added = {2010-01-03 19:37:35 +0100},
date-modified = {2010-07-29 19:21:41 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1103},
rating = {0}
}

@article{Bach:2008p12310,
author = {F R Bach},
title = {Consistency of the Group Lasso and Multiple Kernel Learning},
abstract = {We consider the least-square regression problem with regularization by a block l1-norm, i.e., a sum of Euclidean norms over spaces of dimensions larger than one. This problem, referred to as the group Lasso, extends the usual regularization by the l1-norm where all spaces have dimension one, where it is commonly referred to as the Lasso. In this paper, we study the asymptotic model consistency of the group Lasso. We derive necessary and sufficient conditions for the consistency of group Lasso under practical assumptions, such as model misspecification. When the linear predictors and Euclidean norms are replaced by functions and reproducing kernel Hilbert norms, the problem is usually referred to as multiple kernel learning and is commonly used for learning from heterogeneous data sources and for non linear variable selection. Using tools from functional analysis, and in particular covariance operators, we extend the consistency results to this infinite dimensional case and also propose an adaptive scheme to obtain a consistent model estimate, even when the necessary condition required for the non adaptive scheme is not satisfied.},
year = {2008},
date-added = {2010-06-12 09:27:12 +0200},
date-modified = {2010-06-12 09:28:24 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bach-2008-_Consistency%20of%20the%20G.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12310},
rating = {0}
}

@article{Sun:2010p3690,
author = {J Sun and C Loader and W P McCormick},
title = {Confidence bands in Genralized Linear Models},
date-added = {2010-01-16 20:30:26 +0100},
date-modified = {2010-01-16 20:31:01 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sun--_Confidence%20bands%20in.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3690},
rating = {0}
}

@article{Cremers:2010p12138,
author = {Henk R Cremers and Liliana R Demenescu and Andr{\'e} Aleman and Remco Renken and Marie-Jos{\'e} van Tol and Nic J A van der Wee and Dick J Veltman and Karin Roelofs},
journal = {Neuroimage},
title = {Neuroticism modulates amygdala-prefrontal connectivity in response to negative emotional facial expressions},
abstract = {Neuroticism is associated with the experience of negative affect and the development of affective disorders. While evidence exists for a modulatory role of neuroticism on task induced brain activity, it is unknown how neuroticism affects brain connectivity, especially the crucial coupling between the amygdala and the prefrontal cortex. Here we investigate this relation between functional connectivity and personality in response to negative facial expressions. Sixty healthy control participants, from the Netherlands Study on Depression and Anxiety (NESDA), were scanned during an emotional faces gender decision task. Activity and functional amygdala connectivity (psycho-physiological interaction [PPI]) related to faces of negative emotional valence (angry, fearful and sad) was compared to neutral facial expressions, while neuroticism scores were entered as a regressor. Activity for fearful compared to neutral faces in the dorsomedial prefrontal (dmPFC) cortex was positively correlated with neuroticism scores. PPI analyses revealed that right amygdala-dmPFC connectivity for angry and fearful compared to neutral faces was positively correlated with neuroticism scores. In contrast, left amygdala-anterior cingulate cortex (ACC) connectivity for angry, fearful and sad compared to neutral faces was negatively related to neuroticism levels. DmPFC activity has frequently been associated with self-referential processing in social cognitive tasks. Our results therefore suggest that high neurotic participants display stronger self-referential processing in response to negative emotional faces. Second, in line with previous reports on ACC function, the negative correlation between amygdala-ACC connectivity and neuroticism scores might indicate that those high in neuroticism display diminished control function of the ACC over the amygdala. These connectivity patterns might be associated with vulnerability to developing affective disorders such as depression and anxiety.},
affiliation = {Institute for Psychological Research, Clinical, Health and Neuropsychology Unit, Leiden University, Wassenaarseweg 52, Leiden, The Netherlands. cremershr@fsw.leidenuniv.nl},
number = {1},
pages = {963--70},
volume = {49},
year = {2010},
month = {Jan},
language = {eng},
keywords = {Female, Personality, Facial Expression, Magnetic Resonance Imaging, Prefrontal Cortex, Amygdala, Neurotic Disorders, Young Adult, Neural Pathways, Humans, Photic Stimulation, Image Processing: Computer-Assisted, Anger, Emotions, Middle Aged, Fear, Reaction Time, Male, Personality Tests, Adult},
date-added = {2010-05-30 10:35:53 +0200},
date-modified = {2010-05-30 10:35:54 +0200},
doi = {10.1016/j.neuroimage.2009.08.023},
pii = {S1053-8119(09)00902-1},
pmid = {19683585},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12138},
rating = {0}
}

@article{Jombart:2006p12010,
author = {T Jombart and K Moazami-Goudarzi and A B Dufour and D Laloe},
journal = {Les Actes du BRG},
title = {Fr{\'e}quences all{\'e}liques et coh{\'e}rence entre marqueurs mol{\'e}culaires : des outils descriptifs},
abstract = {The genetic resources have been recognized as a valuable tool to determine genetic structuring of a set of populations and, more specifically, the genetic variations within and among breeds. For this purpose, molecular markers have been successfully used. The aim of this paper is, within the framework of a multivariate analysis, to evaluate how a marker contributes to the genetic structuring of a set of populations. First, we propose tools to represent the information coming from a marker that has been genotyped on a set of populations. Data consist in a table of allelic frequencies over several populations (displayed in rows) for the al- leles of a marker (columns). The goal is to find a genetic structuring of the popula- tions. Using a classical Principal Component Analysis (PCA) is not efficient taking into account the nature of the data. Despite PCA provides well-scattered typologies, it doesn't allow to interpret the position of the populations on the factorial plane. However, a Principal Component Analysis on compositional data (%PCA) yields positions of the populations which are understandable in terms of allelic frequen- cies. In such an analysis, the scores of the populations are the means of the coordi- nates of the alleles, weighted by the allelic frequencies. Hence, the populations are displayed close to the alleles for which they have high frequencies. The position of a population may vary from one sample to another, because the allelic frequencies of a sample are only estimates of the true frequencies. To take this fact into account, we provide confidence ellipses to show the precision around the position of a popu- lation. The confidence ellipse is the area in which the actual population (as opposite to the sample drawn from that population) has a given probability to be within. Confidence ellipses can be used to show whether populations are differenciated by the marker. Two populations are separated if their ellipses do not overlap. The % PCA and confidence ellipses are two useful tools to represent the information of a molecular marker. Second, we consider a set of markers, all of which can be repre- sented as above. We raise the question of finding a meaningful consensus among the typologies provided by each marker. The multiple co-inertia analysis (MCOA) is well adapted to answer this question. MCOA coordinates the representation of each marker in order to highlight their common structures. It provides a typology (i.e. a structure of populations) of reference which best summarizes these similarities. We illustrate the interest of this method using microsatellite data of African and Euro- pean cattle breeds. Indeed, we find two structures between the populations, and we show that the markers contribute differently to this structuring. Some seem ineffi- cient to separate the populations, while others are much more informative. This leads to interesting perspectives about a possible definition of the typological value of molecular markers.},
year = {2006},
date-added = {2010-05-23 17:39:17 +0200},
date-modified = {2010-05-23 17:42:05 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Jombart-2006-Les%20Actes%20du%20BRG_Fre%CC%81quences%20alle%CC%81liq.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12010},
rating = {5}
}

@article{Regnault:2010p12924,
author = {Antoine Regnault and Muriel Viala-Danten and H{\'e}l{\`e}ne Gilet and Gilles Berdeaux},
journal = {BMC Ophthalmol},
title = {Scoring and psychometric properties of the Eye-Drop Satisfaction Questionnaire (EDSQ), an instrument to assess satisfaction and compliance with glaucoma treatment},
abstract = {BACKGROUND: The objective of this study was to ascertain the scoring and assess the psychometric properties of the Eye-Drop Satisfaction Questionnaire (EDSQ), a 43-item Patient-Reported Outcome instrument developed to assess patients' satisfaction and compliance with glaucoma treatment. METHODS: The EDSQ was administered during an observational, retrospective study to 184 French patients treated for glaucoma. The hypothesized structure, including six dimensions (patient-clinician relationship; patient experience; patient-treatment interaction; apprehension; patient knowledge; travel), was tested by assessing the internal consistency reliability (Cronbach's alpha) and construct-related validity (item convergent and discriminant validity). As unsatisfactory results were demonstrated, another structure was defined using a principal component analysis (PCA) combined with content of items. Psychometric properties of this new structure were assessed. Scores were compared between low, moderate and high compliance profile groups defined using data collected with the Travalert electronic device. RESULTS: Analyses were performed with the 169 patients who completed at least half of the EDSQ items. The hypothesized structure showed a Cronbach's alpha lower than 0.70 for four dimensions out of six and an overall poor construct-related validity (range of item-scale correlations: 0.00-0.68). The new structure obtained with the PCA included six dimensions: concern about treatment (five items); concern about disease (two items); satisfaction with patient-clinician relationship (five items); positive beliefs (three items); treatment convenience (three items); and self-declared compliance (three items). A score ranging from 0 to 100 was calculated for each dimension, with higher scores indicating more of the attribute referred to in the dimension. Internal consistency reliability was good (Cronbach's alpha greater than 0.70 for five dimensions). The structure offered good construct-related validity (range of item-scale correlations: 0.36-0.82). Ceiling effects of 21% and 49%, were observed for the satisfaction with patient-clinician relationship and self-declared compliance scores. Patients in low compliance profile group reported the lowest score for the satisfaction with patient-clinician relationship, positive beliefs, treatment convenience and self-declared compliance dimensions, and the highest score for the concern about treatment dimension. CONCLUSIONS: The scoring of the EDSQ was developed and the questionnaire proved to have satisfactory psychometric properties. EDSQ scores showed a promising relationship to compliance profiles. The EDSQ could be used in future studies.},
affiliation = {Mapi Values, Lyon, France. antoine.regnault@mapivalues.com},
pages = {1},
volume = {10},
year = {2010},
month = {Jan},
language = {eng},
keywords = {Questionnaires, Adult, Physician-Patient Relations, Female, Adolescent, Young Adult, Retrospective Studies, Aged: 80 and over, Middle Aged, Male, Patient Satisfaction, Glaucoma: Open-Angle, Cross-Sectional Studies, Ophthalmic Solutions, Aged, Humans, Reproducibility of Results, Psychometrics, Drug Delivery Systems, Principal Component Analysis, Patient Compliance},
date-added = {2010-06-25 21:42:30 +0200},
date-modified = {2010-06-25 21:42:43 +0200},
doi = {10.1186/1471-2415-10-1},
pii = {1471-2415-10-1},
pmid = {20122146},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Regnault-2010-BMC%20Ophthalmol_Scoring%20and%20psychome.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12924},
rating = {5}
}

@article{Keinan:2010p11308,
author = {Alon Keinan and David Reich},
journal = {PLoS Genet},
title = {Human population differentiation is strongly correlated with local recombination rate},
abstract = {Allele frequency differences across populations can provide valuable information both for studying population structure and for identifying loci that have been targets of natural selection. Here, we examine the relationship between recombination rate and population differentiation in humans by analyzing two uniformly-ascertained, whole-genome data sets. We find that population differentiation as assessed by inter-continental F(ST) shows negative correlation with recombination rate, with F(ST) reduced by 10% in the tenth of the genome with the highest recombination rate compared with the tenth of the genome with the lowest recombination rate (P<<10(-12)). This pattern cannot be explained by the mutagenic properties of recombination and instead must reflect the impact of selection in the last 100,000 years since human continental populations split. The correlation between recombination rate and F(ST) has a qualitatively different relationship for F(ST) between African and non-African populations and for F(ST) between European and East Asian populations, suggesting varying levels or types of selection in different epochs of human history.},
affiliation = {Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America. ak735@cornell.edu},
number = {3},
pages = {e1000886},
volume = {6},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-04-26 23:05:45 +0200},
date-modified = {2010-04-26 23:05:45 +0200},
doi = {10.1371/journal.pgen.1000886},
pmid = {20361044},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Keinan-2010-PLoS%20Genet_Human%20population%20dif.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11308},
rating = {0}
}

@misc{Rehder:1998,
author = {B Rehder and M E Schreiner and M B W Wolfe and D Laham},
journal = {Miscellaneous},
title = {Using latent semantic analysis to assess knowledge: Some technical considerations},
year = {1998},
date-added = {2010-01-10 11:33:24 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rehder-1998-Miscellaneous_Using%20latent%20semanti.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2174},
rating = {0}
}

@article{Grucza:2007p13920,
author = {Richard A Grucza and Lewis R Goldberg},
journal = {J Pers Assess},
title = {The comparative validity of 11 modern personality inventories: predictions of behavioral acts, informant reports, and clinical indicators},
abstract = {In science, multiple measures of the same constructs can be useful, but they are unlikely to all be equally valid indicators. In psychological assessment, the many popular personality inventories available in the marketplace also may be useful, but their comparative validity has long remained unassessed. This is the first comprehensive comparison of 11 such multiscale instruments against each of three types of criteria: clusters of behavioral acts, descriptions by knowledgeable informants, and clinical indicators potentially associated with various types of psychopathology. Using 1,000 bootstrap resampling analyses from a sample of roughly 700 adult research participants, we assess the relative predictability of each criterion and the comparative validity of each inventory. Although there was a wide range of criterion predictability, most inventories exhibited quite similar cross-validities when averaged across all three types of criteria. On the other hand, there were important differences between inventories in their predictive capabilities for particular criteria. We discuss the factors that lead to differential validity across predictors and criteria.},
affiliation = {Department of Psychiatry, Washington University School of Medicine, USA.},
number = {2},
pages = {167--87},
volume = {89},
year = {2007},
month = {Oct},
language = {eng},
keywords = {Male, Humans, Personality Tests, Psychometrics, Oregon, Aged, Reproducibility of Results, Social Behavior, Personality, Middle Aged, Adult, Personality Assessment, Personality Inventory, Regression Analysis, Female},
date-added = {2010-07-29 18:44:11 +0200},
date-modified = {2010-07-29 19:35:42 +0200},
doi = {10.1080/00223890701468568},
pmid = {17764394},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Grucza-2007-J%20Pers%20Assess_The%20comparative%20vali.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13920},
rating = {4}
}

@article{Kim:2009p1620,
author = {Yoonhee Kim and Robert Wojciechowski and Heejong Sung and Rasika A Mathias and Li Wang and Alison P Klein and Rhoshel K Lenroot and James Malley and Joan E Bailey-Wilson},
journal = {BMC Proc},
title = {Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects},
abstract = {ABSTRACT : Random forests (RF) is one of a broad class of machine learning methods that are able to deal with large-scale data without model specification, which makes it an attractive method for genome-wide association studies (GWAS). The performance of RF and other association methods in the presence of interactions was evaluated using the simulated data from Genetic Analysis Workshop 16 Problem 3, with knowledge of the major causative markers, risk factors, and their interactions in the simulated traits. There was good power to detect the environmental risk factors using RF, trend tests, or regression analyses but the power to detect the effects of the causal markers was poor for all methods. The causal marker that had an interactive effect with smoking did show moderate evidence of association in the RF and regression analyses, suggesting that RF may perform well at detecting such interactions in larger, more highly powered datasets.},
affiliation = {National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA. kimyoo@mail.nih.gov.},
pages = {S64},
volume = {3 Suppl 7},
year = {2009},
month = {Jan},
language = {eng},
date-added = {2010-01-08 21:49:28 +0100},
date-modified = {2010-07-29 19:21:18 +0200},
pmid = {20018058},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kim-2009-BMC%20Proc_Evaluation%20of%20random.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1620},
read = {Yes},
rating = {0}
}

@article{Sabb:2009p3015,
author = {F W Sabb and A C Burggren and R G Higier and J Fox and J He and D S Parker and R A Poldrack and W Chu and T D Cannon and N B Freimer and R M Bilder},
journal = {Neuroscience},
title = {Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence},
abstract = {Refining phenotypes for the study of neuropsychiatric disorders is of paramount importance in neuroscience. Poor phenotype definition provides the greatest obstacle for making progress in disorders like schizophrenia, bipolar disorder, Attention Deficit/Hyperactivity Disorder (ADHD), and autism. Using freely available informatics tools developed by the Consortium for Neuropsychiatric Phenomics (CNP), we provide a framework for defining and refining latent constructs used in neuroscience research and then apply this strategy to review known genetic contributions to memory and intelligence in healthy individuals. This approach can help us begin to build multi-level phenotype models that express the interactions between constructs necessary to understand complex neuropsychiatric diseases. These results are available online through the http://www.phenowiki.org database. Further work needs to be done in order to provide consensus-building applications for the broadly defined constructs used in neuroscience research.},
affiliation = {Consortium for Neuropsychiatric Phenomics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA. fsabb@ucla.edu},
number = {1},
pages = {88--107},
volume = {164},
year = {2009},
month = {Nov},
language = {eng},
keywords = {Multivariate Analysis, Genome, Memory, Humans, Models: Genetic, Intelligence, Phenotype},
date-added = {2010-01-14 11:23:42 +0100},
date-modified = {2010-07-29 19:41:38 +0200},
doi = {10.1016/j.neuroscience.2009.05.013},
pii = {S0306-4522(09)00795-7},
pmid = {19450667},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3015},
rating = {0}
}

@article{Wittchen:2009p3957,
author = {Hans-Ulrich Wittchen and Katja Beesdo-Baum and Andrew T Gloster and Michael H{\"o}fler and Jens Klotsche and Roselind Lieb and Andr{\'e} Beauducel and Markus B{\"u}hner and Ronald C Kessler},
journal = {Int J Methods Psychiatr Res},
title = {The structure of mental disorders re-examined: is it developmentally stable and robust against additions?},
abstract = {Previous research suggests that patterns of comorbidity of a limited number of anxiety, depressive, substance use and antisocial personality (ASP) disorders among adults are best reflected by a hierarchical three-factor structure with two correlated factors ('anxious-misery' and 'fear') that are summarized in a second-order 'internalizing' factor and one 'externalizing' factor. It has not been examined whether this structure is developmentally stable and robust against additions of more diagnoses. Using data from a prospective-longitudinal community study of adolescents and young adults we re-evaluate the three-factor model originally proposed by Krueger (Archives of General Psychiatry, 1999; 56, 921-926). Using confirmatory factor analysis with identical conventions as in Krueger's original work we found that the three factor model did not fit robustly across age or a wider range of diagnoses. Using explanatory factor analysis we examined alternative structures. We found various clinically meaningful patterns with good fit that go substantially beyond the original three-factor structure. However, again, there is little consistency in findings when different age groups or different diagnoses are considered. Our findings suggest that psychopathology cannot be reduced to any simple structure.},
affiliation = {Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany. wittchen@psychologie.tu-dresden.de},
number = {4},
pages = {189--203},
volume = {18},
year = {2009},
month = {Dec},
language = {eng},
date-added = {2010-01-17 11:58:13 +0100},
date-modified = {2010-01-17 11:58:13 +0100},
doi = {10.1002/mpr.298},
pmid = {20033884},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3957},
rating = {0}
}

@article{Buchanan:2005p13883,
author = {T Buchanan and J A Johnson and L R Goldberg},
journal = {European Journal of Psychology of Education},
title = {Implementing a Five-Factor personality inventory for use on the Internet},
number = {2},
pages = {115--127},
volume = {21},
year = {2005},
date-added = {2010-07-29 18:00:27 +0200},
date-modified = {2010-07-29 18:03:36 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Buchanan-2005-European%20Journal%20of%20Psychological%20Assessment_Implementing%20a%20Five.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13883},
rating = {3}
}

@article{Moher:2010p5766,
author = {D Moher and K F Schulz and I Simera and Douglas G Altman},
journal = {PLoS Med},
title = {Guidance for Developers of Health Research Reporting Guidelines},
number = {2},
pages = {e1000217},
volume = {7},
year = {2010},
date-added = {2010-02-16 12:07:42 +0100},
date-modified = {2010-07-29 20:20:56 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Moher-2010-PLoS%20Med_Guidance%20for%20Develop.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5766},
rating = {0}
}

@article{DelaTorre:2009p13235,
author = {F De la Torre and T Kanade},
title = {Discriminative Cluster Analysis},
abstract = {Clustering is one of the most widely used statistical tools for data analy- sis. Among all existing clustering techniques, k-means is a very popular method due to its ease of programming and its good trade-off between achieved performance and computational complexity. However, k-means is prone to local minima prob- lems and does not scale well with high dimensional data sets. A common approach to clustering high dimensional data is to project in the space spanned by the prin- cipal components (PC). However, the space of PCs does not necessarily improve the separability of the clusters. In this paper, we propose Discriminative Cluster Analysis (DCA) that clusters data in a low dimensional discriminative that encour- ages cluster separability. DCA simultaneously performs dimensionality reduction and clustering, improving efficiency and cluster performance in comparison with generative approaches (e.g. PC). We exemplify the benefits of DCA versus tradi- tional PCA+k-means clustering through several synthetic and real examples. Addi- tionally, we provide connections with other dimensionality reduction and clustering techniques such as spectral graph methods and linear discriminant analysis.},
year = {2009},
date-added = {2010-07-01 17:43:49 +0200},
date-modified = {2010-07-01 17:44:46 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/De%20la%20Torre-2009-_Discriminative%20Clust.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13235},
rating = {4}
}

@article{Rogers:2008p5577,
author = {T T Rogers and J L McClelland},
journal = {Behavioral and Brain Sciences},
title = {Pr{\'e}cis of Semantic Cognition: A Parallel Distributed Processing Approach},
abstract = {In this pr{\'e}cis of our recent book, Semantic Cognition: A Parallel Distributed Processing Approach (Rogers {\&} McClelland 2004), we present a parallel distributed processing theory of the acquisition, representation, and use of human semantic knowledge. The theory proposes that semantic abilities arise from the flow of activation among simple, neuron-like processing units, as governed by the strengths of interconnecting weights; and that acquisition of new semantic information involves the gradual adjustment of weights in the system in response to experience. These simple ideas explain a wide range of empirical phenomena from studies of categorization, lexical acquisition, and disordered semantic cognition. In this pre ́cis we focus on phenomena central to the reaction against similarity-based theories that arose in the 1980s and that subsequently motivated the ``theory-theory'' approach to semantic knowledge. Specifically, we consider (1) how concepts differentiate in early development, (2) why some groupings of items seem to form ``good'' or coherent categories while others do not, (3) why different properties seem central or important to different concepts, (4) why children and adults sometimes attest to beliefs that seem to contradict their direct experience, (5) how concepts reorganize between the ages of 4 and 10, and (6) the relationship between causal knowledge and semantic knowledge. The explanations our theory offers for these phenomena are illustrated with reference to a simple feed- forward connectionist model. The relationships between this simple model, the broader theory, and more general issues in cognitive science are discussed.},
pages = {689--749},
volume = {31},
year = {2008},
date-added = {2010-02-12 15:35:45 +0100},
date-modified = {2010-02-12 15:36:47 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rogers-2008-Behavioral%20and%20Brain%20Sciences_Pr%C3%A9cis%20of%20Semantic%20C.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5577},
rating = {0}
}

@article{Fox:2005a,
author = {Jean-Paul Fox},
journal = {British Journal of Mathematical {\&} Statistical Psychology},
title = {Multilevel IRT using dichotomous and polytomous response data},
pages = {145--172},
volume = {58},
year = {2005},
date-added = {2010-01-10 11:33:22 +0100},
date-modified = {2010-07-29 19:22:13 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fox-2005-British%20Journal%20of%20Mathematical%20&%20Statistical%20Psychology_Multilevel%20IRT%20using.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1942},
rating = {0}
}

@article{Bouchet:1996p9836,
author = {C Bouchet and F Guillemin and T H Hoang Thi and A Cornette and S Brian{\c c}on},
journal = {Revue des Maladies Respiratoires},
title = {Validation du questionnaire St Georges pour mesurer la qualit{\'e} de vie chez les insuffisants respiratoires chroniques},
abstract = {The validity of a French version of a disease specific quality of life instrument, the St George's Respiratory Questionnaire, has been assessed in a sample of 64 patients with chronic respiratory disease undergoing oxygen therapy. The studied properties were internal consistency, test-retest reproducibility and criterion validity. The St Georges showed a good internal consistency with Cronbach's alpha coefficients from 0.61 to 0.95 and a good reproducibility with Intraclass Correlation Coefficients (ICC) from 0.67 to 0.95. High correlation with dyspnea (p = 0.0004 to 0.01) showed a correct criterion validity. So psychometric properties of the French version of the questionnaire are good. However, its administration caused a few problems, and we advice it to be administered by a trained interviewer in such patients.},
pages = {43--46},
volume = {13},
year = {1996},
date-added = {2010-03-26 19:25:49 +0100},
date-modified = {2010-03-26 19:27:00 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bouchet-1996-Revue%20des%20Maladies%20Respiratoires_Validation%20du%20questi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9836},
rating = {0}
}

@article{Gilbert:2009p13491,
author = {E Gilbert and K Karahalios},
title = {Widespread Worry and the Stock Market},
abstract = {Our emotional state influences our choices. Research on how it happens usually comes from the lab. We know rela- tively little about how real world emotions affect real world settings, like financial markets. Here, we demonstrate that estimating emotions from weblogs provides novel informa- tion about future stock market prices. That is, it provides information not already apparent from market data. Specifi- cally, we estimate anxiety, worry and fear from a dataset of over 20 million posts made on the site LiveJournal. Using a Granger-causal framework, we find that increases in expres- sions of anxiety, evidenced by computationally-identified linguistic features, predict downward pressure on the S{\&}P 500 index. We also present a confirmation of this result via Monte Carlo simulation. The findings show how the mood of millions in a large online community, even one that pri- marily discusses daily life, can anticipate changes in a seem- ingly unrelated system. Beyond this, the results suggest new ways to gauge public opinion and predict its impact.},
year = {2009},
date-added = {2010-07-01 22:25:39 +0200},
date-modified = {2010-07-01 22:26:34 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gilbert-2009-_Widespread%20Worry%20and.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13491},
rating = {0}
}

@article{Nyholt:2005p2235,
author = {Dale R Nyholt and Katherine I Morley and Manuel A R Ferreira and Sarah E Medland and Dorret I Boomsma and Andrew C Heath and Kathleen R Merikangas and Grant W Montgomery and Nicholas G Martin},
journal = {Am J Hum Genet},
title = {Genomewide significant linkage to migrainous headache on chromosome 5q21},
abstract = {Familial typical migraine is a common, complex disorder that shows strong familial aggregation. Using latent-class analysis (LCA), we identified subgroups of people with migraine/severe headache in a community sample of 12,245 Australian twins (60% female), drawn from two cohorts of individuals aged 23-90 years who completed an interview based on International Headache Society criteria. We report results from genomewide linkage analyses involving 756 twin families containing a total of 790 independent sib pairs (130 affected concordant, 324 discordant, and 336 unaffected concordant for LCA-derived migraine). Quantitative-trait linkage analysis produced evidence of significant linkage on chromosome 5q21 and suggestive linkage on chromosomes 8, 10, and 13. In addition, we replicated previously reported typical-migraine susceptibility loci on chromosomes 6p12.2-p21.1 and 1q21-q23, the latter being within 3 cM of the rare autosomal dominant familial hemiplegic migraine gene (ATP1A2), a finding which potentially implicates ATP1A2 in familial typical migraine for the first time. Linkage analyses of individual migraine symptoms for our six most interesting chromosomes provide tantalizing hints of the phenotypic and genetic complexity of migraine. Specifically, the chromosome 1 locus is most associated with phonophobia; the chromosome 5 peak is predominantly associated with pulsating headache; the chromosome 6 locus is associated with activity-prohibiting headache and photophobia; the chromosome 8 locus is associated with nausea/vomiting and moderate/severe headache; the chromosome 10 peak is most associated with phonophobia and photophobia; and the chromosome 13 peak is completely due to association with photophobia. These results will prove to be invaluable in the design and analysis of future linkage and linkage disequilibrium studies of migraine.},
affiliation

repository: sergiud/bibtex-spirit

repo_name: sergiud/bibtex-spirit

gha_license_id: MIT