text:
in Alabama (p<0.001) and higher in New Jersey (p<0.0001). ASD prevalence varied by identification source, with higher average prevalence for ASDs in sites with access to health and education records (mean: 7.2) compared with sites with health records only (mean: 5.1). Five sites identified a higher prevalence of ASDs for non-Hispanic white children than for non-Hispanic black children. The ratio of males to females ranged from 3.4:1.0 in Maryland, South Carolina, and Wisconsin to 6.5:1.0 in Utah. The majority of children were receiving special education services at age 8 years and had a documented history of concerns regarding their development before age 3 years. However, the median age of earliest documented ASD diagnosis was much later (range: 49 months [Utah]--66 months [Alabama]). The proportion of children with characteristics consistent with the criteria for an ASD classification who had a previously documented ASD classification varied across sites. In the majority of sites, females with an ASD were more likely than males to have cognitive impairment. For the six sites for which prevalence data were available from both 2000 and 2002, ASD prevalence was stable in four sites and increased in two sites (17% in Georgia and 39% in West Virginia). INTERPRETATION: Results from the second report of a U.S. multisite collaboration to monitor ASD prevalence demonstrated consistency of prevalence in the majority of sites, with variation in two sites. Prevalence was stable in the majority of sites for which 2 years of data were available, but an increase in West Virginia and a trend toward an increase in Georgia indicate the need for ongoing monitoring of ASD prevalence. PUBLIC HEALTH ACTIONS: These ASD prevalence data provide the most complete information on the prevalence of the ASDs in the United States to date. The data confirm that ASD prevalence is a continuing urgent public health concern affecting an approximate average of one child in every 150 and that efforts are needed to improve early identification of ASDs.},
number = {1},
pages = {12--28},
volume = {56},
year = {2007},
month = {Feb},
language = {eng},
keywords = {Population Surveillance, Female, Autistic Disorder, Asperger Syndrome, Child Development Disorders: Pervasive, Child, Prevalence, United States, Humans, Male},
date-added = {2010-02-19 17:03:45 +0100},
date-modified = {2010-02-19 17:03:46 +0100},
pii = {ss56a01a2},
pmid = {17287715},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6081},
rating = {0}
}

@article{Thompson:2002p9832,
author = {Paul Thompson and Tyrone D Cannon and Arthur W Toga},
journal = {Ann Med},
title = {Mapping genetic influences on human brain structure},
abstract = {Recent advances in brain imaging and genetics have empowered the mapping of genetic and environmental influences on the human brain. These techniques shed light on the 'nature/nurture' debate, revealing how genes determine individual differences in intelligence quotient (IQ) or risk for disease. They visualize which aspects of brain structure and function are heritable, and to what degree, linking these features with behavioral or cognitive traits or disease phenotypes. In genetically transmitted disorders such as schizophrenia, patterns of brain structure can be associated with increased disease liability, and sites can be mapped where non-genetic triggers may initiate disease. We recently developed a large-scale computational brain atlas, including data components from the Finnish Twin registry, to store information on individual variations in brain structure and their heritability. Algorithms from random field theory, anatomical modeling, and population genetics were combined to detect a genetic continuum in which brain structure is heavily genetically determined in some areas but not others. These algorithmic advances motivate studies of disease in which the normative atlas acts as a quantitative reference for the heritability of structural differences and deficits in patient populations. The resulting genetic brain maps isolate biological markers for inherited traits and disease susceptibility, which may serve as targets for genetic linkage and association studies. Computational methods from brain imaging and genetics can be fruitfully merged, to shed light on the inheritance of personality differences and behavioral traits, and the genetic transmission of diseases that affect the human brain.},
affiliation = {Laboratory of Neuro Imaging and Brain Mapping Division, Department of Neurology, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA. thompson@loni.ucla.edu},
number = {7-8},
pages = {523--36},
volume = {34},
year = {2002},
month = {Jan},
language = {eng},
keywords = {Humans, Genetics: Population, Brain Diseases, Algorithms, Brain, Genetic Predisposition to Disease, Intelligence},
date-added = {2010-03-26 19:23:00 +0100},
date-modified = {2010-03-26 19:23:00 +0100},
pmid = {12553492},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Thompson-2002-Ann%20Med_Mapping%20genetic%20infl.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9832},
rating = {0}
}

@article{Kintsch:1999,
author = {Walter Kintsch and Vimla L Patel and K Anders Ericsson},
journal = {Psychologia},
title = {The role of long-term memory in text comprehension},
pages = {186--198},
volume = {42},
year = {1999},
date-added = {2010-01-10 11:33:24 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kintsch-1999-Psychologia_The%20role%20of%20long-ter.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1877},
rating = {0}
}

@article{Gelman:2010p12904,
author = {A Gelman and I Leenen and I Van Mechelen and Paul De Boeck and J Poblome},
journal = {Statistical Methodology},
title = {Bridges between deterministic and probabilistic models for binary data},
abstract = {For the analysis of binary data, various deterministic models have been proposed, which are generally simpler to fit and easier to understand than probabilistic models. We claim that corresponding to any deterministic model is an implicit stochastic model in which the deterministic model fits imperfectly, with errors occurring at random. In the context of binary data, we consider a model in which the probability of error depends on the model prediction. We show how to fit this model using a stochastic modification of deterministic optimization schemes.
The advantages of fitting the stochastic model explicitly (rather than implicitly, by simply fitting a deterministic model and accepting the occurrence of errors) include quantification of uncertainty in the deterministic model's parameter estimates, better estimation of the true model error rate, and the ability to check the fit of the model nontrivially. We illustrate this with a simple theoretical example of item response data and with empirical examples from archeology and the psychology of choice.},
pages = {187--209},
volume = {7},
year = {2010},
date-added = {2010-06-24 17:27:21 +0200},
date-modified = {2010-07-29 20:46:12 +0200},
doi = {10.1016/j.stamet.2009.08.005},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gelman-2010-Statistical%20Methodology_Bridges%20between%20dete.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12904},
rating = {0}
}

@article{Kiiveri:2008p12950,
author = {Harri T Kiiveri},
journal = {BMC Bioinformatics},
title = {A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more variables than observations},
abstract = {BACKGROUND: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables than observations are now routinely being collected. Finding relationships between response variables of interest and variables in such data sets is an important problem akin to finding needles in a haystack. Whilst methods for a number of response types have been developed a general approach has been lacking. RESULTS: The major contribution of this paper is to present a unified methodology which allows many common (statistical) response models to be fitted to such data sets. The class of models includes virtually any model with a linear predictor in it, for example (but not limited to), multiclass logistic regression (classification), generalised linear models (regression) and survival models. A fast algorithm for finding sparse well fitting models is presented. The ideas are illustrated on real data sets with numbers of variables ranging from thousands to millions. R code implementing the ideas is available for download. CONCLUSION: The method described in this paper enables existing work on response models when there are less variables than observations to be leveraged to the situation when there are many more variables than observations. It is a powerful approach to finding parsimonious models for such datasets. The method is capable of handling problems with millions of variables and a large variety of response types within the one framework. The method compares favourably to existing methods such as support vector machines and random forests, but has the advantage of not requiring separate variable selection steps. It is also works for data types which these methods were not designed to handle. The method usually produces very sparse models which make biological interpretation simpler and more focused.},
affiliation = {CSIRO Mathematical and Information Sciences, The Leeuwin Center, 65 Brockway Road, Floreat, 6014, Western Australia. harri.kiiveri@csiro.au},
pages = {195},
volume = {9},
year = {2008},
month = {Jan},
language = {eng},
keywords = {Reference Values, Male, Research Design, Software, Gene Expression Profiling, Models: Statistical, Prostatic Neoplasms, Female, Information Storage and Retrieval, Models: Biological, Neoplasm Staging, Pattern Recognition: Automated, Leukemia, Humans, Oligonucleotide Array Sequence Analysis, Smoking, Lymphoma},
date-added = {2010-06-25 22:07:54 +0200},
date-modified = {2010-06-25 22:07:54 +0200},
doi = {10.1186/1471-2105-9-195},
pii = {1471-2105-9-195},
pmid = {18410693},
URL = {http://www.biomedcentral.com/1471-2105/9/195},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kiiveri-2008-BMC%20Bioinformatics_A%20general%20approach%20t.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12950},
rating = {0}
}

@article{Ioannidis:2007p2301,
author = {John P A Ioannidis and Nikolaos A Patsopoulos and Evangelos Evangelou},
journal = {PLoS ONE},
title = {Heterogeneity in meta-analyses of genome-wide association investigations},
abstract = {BACKGROUND: Meta-analysis is the systematic and quantitative synthesis of effect sizes and the exploration of their diversity across different studies. Meta-analyses are increasingly applied to synthesize data from genome-wide association (GWA) studies and from other teams that try to replicate the genetic variants that emerge from such investigations. Between-study heterogeneity is important to document and may point to interesting leads. METHODOLOGY/PRINCIPAL FINDINGS: To exemplify these issues, we used data from three GWA studies on type 2 diabetes and their replication efforts where meta-analyses of all data using fixed effects methods (not incorporating between-study heterogeneity) have already been published. We considered 11 polymorphisms that at least one of the three teams has suggested as susceptibility loci for type 2 diabetes. The I2 inconsistency metric (measuring the amount of heterogeneity not due to chance) was different from 0 (no detectable heterogeneity) for 6 of the 11 genetic variants; inconsistency was moderate to very large (I2 = 32-77%) for 5 of them. For these 5 polymorphisms, random effects calculations incorporating between-study heterogeneity revealed more conservative p-values for the summary effects compared with the fixed effects calculations. These 5 associations were perused in detail to highlight potential explanations for between-study heterogeneity. These include identification of a marker for a correlated phenotype (e.g. FTO rs8050136 being associated with type 2 diabetes through its effect on obesity); differential linkage disequilibrium across studies of the identified genetic markers with the respective culprit polymorphisms (e.g., possibly the case for CDKAL1 polymorphisms or for rs9300039 and markers in linkage disequilibrium, as shown by additional studies); and potential bias. Results were largely similar, when we treated the discovery and replication data from each GWA investigation as separate studies. SIGNIFICANCE: Between-study heterogeneity is useful to document in the synthesis of data from GWA investigations and can offer valuable insights for further clarification of gene-disease associations.},
affiliation = {Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. jioannid@cc.uoi.gr},
number = {9},
pages = {e841},
volume = {2},
year = {2007},
month = {Jan},
language = {eng},
date-added = {2010-01-10 12:13:58 +0100},
date-modified = {2010-01-10 12:14:01 +0100},
doi = {10.1371/journal.pone.0000841},
pmid = {17786212},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ioannidis-2007-PLoS%20ONE_Heterogeneity%20in%20met.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2301},
rating = {4}
}

@article{Steiger:1994p2430,
author = {J Steiger},
title = {Factor Analysis in the 1980's and the 1990's: Some Old Debates and Some New Developments},
year = {1994},
date-added = {2010-01-11 23:33:11 +0100},
date-modified = {2010-01-12 13:39:05 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Steiger-1994-_Factor%20Analysis%20in%20t.PDF},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2430},
read = {Yes},
rating = {0}
}

@article{vanDoorslaer:2003p6966,
author = {Eddy van Doorslaer and Andrew M Jones},
journal = {J Health Econ},
title = {Inequalities in self-reported health: validation of a new approach to measurement},
abstract = {This paper assesses the internal validity of using the McMaster 'Health Utility Index Mark III' (HUI) to scale the responses on the typical self-assessed health (SAH) question, "how do you rate your health status in general?" It compares alternative procedures to impose cardinality on the ordinal responses. These include OLS, ordered probit and interval regression approaches. The cardinal measures of health are used to compute and to decompose concentration indices for income-related inequality in health. These results are validated by comparison with the individual variation in the 'benchmark' HUI responses obtained from the Canadian 'National Population Health Survey 1994-1995'. The interval regression approach, which exploits a mapping from the empirical distribution function (EDF) of HUI into SAH, outperforms the other approaches. In addition, we show how the method can be extended to allow for differences in SAH thresholds across different groups of people and to measuring and decomposing 'pure' health inequality.},
affiliation = {Department of Health Policy and Management, Erasmus University, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. vandoorslaer@bmg.eur.nl},
number = {1},
pages = {61--87},
volume = {22},
year = {2003},
month = {Jan},
language = {eng},
keywords = {Health Status Indicators, Regression Analysis, Bias (Epidemiology), Models: Econometric, Humans, Canada, Self Assessment (Psychology), Socioeconomic Factors},
date-added = {2010-03-06 12:24:54 +0100},
date-modified = {2010-03-06 12:24:54 +0100},
pmid = {12564718},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6966},
rating = {0}
}

@article{Breitscheidel:2009p7302,
author = {Lusine Breitscheidel and Sabine Stamenitis},
journal = {J Med Econ},
title = {Using patient-reported outcome assessments in clinical practice and their importance in risk management},
abstract = {Patient-reported outcome (PRO) instruments are related to risk management programmes in that they are tools to measure the benefits and risks of exposure to pharmaceutical products from the patient's perspective. Clinical measures of improvement of certain conditions may not necessarily correlate with improvements in a patient's ability to perform daily activities. PRO data, when properly administered, collected, analysed and returned to physicians are a very useful source of information. This will ultimately address safety concerns, facilitate the physician-patient relationship and improve patients' compliance to treatment in routine patient care. In this article we stress the importance of PRO in risk management.},
affiliation = {Kendle GmbH, Munich, Germany. breitscheidel.lusine@kendle.com},
number = {3},
pages = {180--1},
volume = {12},
year = {2009},
month = {Sep},
language = {eng},
date-added = {2010-03-10 20:21:00 +0100},
date-modified = {2010-03-10 20:21:00 +0100},
doi = {10.3111/13696990903216278},
pmid = {19691445},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7302},
rating = {0}
}

@article{Eytan:2007p7457,
author = {Ariel Eytan and Sophie Durieux-Paillard and Barbara Whitaker-Clinch and Louis Loutan and Patrick A Bovier},
journal = {J Nerv Ment Dis},
title = {Transcultural validity of a structured diagnostic interview to screen for major depression and posttraumatic stress disorder among refugees},
abstract = {Refugees and asylum seekers have a high risk of developing mental health problems and appropriate screening in people from diverse origins remains a challenge. The aim of this study was to validate a structured diagnostic interview, adapted from the Major Depressive Episode (MDE) and Posttraumatic Stress Disorder (PTSD) sections of the Mini International Neuropsychiatric Interview, to detect these disorders among newly arrived asylum seekers. The adapted questionnaire was administered by nurses in a primary care context and its performance was judged against the expert opinion of a mental health specialist. One hundred one subjects were included in the study (mean age: 30; origin: Africa 58%, Europe: 37%, Asia: 5%). MDE and PTSD were diagnosed among 33% and 30% of them respectively. The questionnaire demonstrated moderate sensitivity (MDE: 79%; PTSD: 69%), but high specificity (MDE: 95%; PTSD: 94%). These characteristics remained stable despite cultural differences and use of interpreters. This instrument could be used for systematic screening of MDE and PTSD in refugees from various origins.},
affiliation = {Adult Psychiatry Service, Department of Psychiatry, Geneva University Hospitals, Ch{\^e}ne-Bourg, Switzerland. Ariel.Eytan@hcuge.ch},
number = {9},
pages = {723--8},
volume = {195},
year = {2007},
month = {Sep},
language = {eng},
keywords = {African Continental Ancestry Group, Asian Continental Ancestry Group, Questionnaires, Primary Health Care, Switzerland, Reproducibility of Results, Female, Emigration and Immigration, Stress Disorders: Post-Traumatic, Adult, Humans, Refugees, Male, European Continental Ancestry Group, Cross-Cultural Comparison, Psychiatric Status Rating Scales, Sensitivity and Specificity, Prevalence, Depressive Disorder: Major},
date-added = {2010-03-10 20:42:42 +0100},
date-modified = {2010-03-10 20:42:42 +0100},
doi = {10.1097/NMD.0b013e318142c9f6},
pii = {00005053-200709000-00002},
pmid = {17984771},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7457},
rating = {0}
}

@article{McGary:2010p11435,
author = {Kriston L McGary and Tae Joo Park and John O Woods and Hye Ji Cha and John B Wallingford and Edward M Marcotte},
journal = {Proc Natl Acad Sci USA},
title = {Systematic discovery of nonobvious human disease models through orthologous phenotypes},
abstract = {Biologists have long used model organisms to study human diseases, particularly when the model bears a close resemblance to the disease. We present a method that quantitatively and systematically identifies nonobvious equivalences between mutant phenotypes in different species, based on overlapping sets of orthologous genes from human, mouse, yeast, worm, and plant (212,542 gene-phenotype associations). These orthologous phenotypes, or phenologs, predict unique genes associated with diseases. Our method suggests a yeast model for angiogenesis defects, a worm model for breast cancer, mouse models of autism, and a plant model for the neural crest defects associated with Waardenburg syndrome, among others. Using these models, we show that SOX13 regulates angiogenesis, and that SEC23IP is a likely Waardenburg gene. Phenologs reveal functionally coherent, evolutionarily conserved gene networks-many predating the plant-animal divergence-capable of identifying candidate disease genes.},
affiliation = {Department of Molecular Cell and Developmental Biology, Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA.},
number = {14},
pages = {6544--9},
volume = {107},
year = {2010},
month = {Apr},
language = {eng},
date-added = {2010-05-01 17:17:21 +0200},
date-modified = {2010-05-01 17:17:22 +0200},
doi = {10.1073/pnas.0910200107},
pii = {0910200107},
pmid = {20308572},
local-url = {file://localhost/Users/chl/Dropbox/Papers/McGary-2010-Proc%20Natl%20Acad%20Sci%20USA_Systematic%20discovery.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11435},
rating = {0}
}

@article{Glaser:2007p2287,
author = {Beate Glaser and Ivan Nikolov and Daniel Chubb and Marian L Hamshere and Ricardo Segurado and Valentina Moskvina and Peter Holmans},
journal = {BMC Proc},
title = {Analyses of single marker and pairwise effects of candidate loci for rheumatoid arthritis using logistic regression and random forests},
abstract = {Using parametric and nonparametric techniques, our study investigated the presence of single locus and pairwise effects between 20 markers of the Genetic Analysis Workshop 15 (GAW15) North American Rheumatoid Arthritis Consortium (NARAC) candidate gene data set (Problem 2), analyzing 463 independent patients and 855 controls. Specifically, our work examined the correspondence between logistic regression (LR) analysis of single-locus and pairwise interaction effects, and random forest (RF) single and joint importance measures. For this comparison, we selected small but stable RFs (500 trees), which showed strong correlations (r~0.98) between their importance measures and those by RFs grown on 5000 trees. Both RF importance measures captured most of the LR single-locus and pairwise interaction effects, while joint importance measures also corresponded to full LR models containing main and interaction effects. We furthermore showed that RF measures were particularly sensitive to data imputation. The most consistent pairwise effect on rheumatoid arthritis was found between two markers within MAP3K7IP2/SUMO4 on 6q25.1, although LR and RFs assigned different significance levels.Within a hypothetical two-stage design, pairwise LR analysis of all markers with significant RF single importance would have reduced the number of possible combinations in our small data set by 61%, whereas joint importance measures would have been less efficient for marker pair reduction. This suggests that RF single importance measures, which are able to detect a wide range of interaction effects and are computationally very efficient, might be exploited as pre-screening tool for larger association studies. Follow-up analysis, such as by LR, is required since RFs do not indicate high-risk genotype combinations.},
affiliation = {Biostatistics and Bioinformatics Unit, and Department of Psychological Medicine, Cardiff University, School of Medicine, Heath Park, Cardiff, Wales, CF14 4XN, UK. B.Glaser@Bristol.ac.uk},
pages = {S54},
volume = {1 Suppl 1},
year = {2007},
month = {Jan},
language = {eng},
date-added = {2010-01-10 12:02:43 +0100},
date-modified = {2010-01-10 12:02:43 +0100},
pmid = {18466554},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Glaser-2007-BMC%20Proc_Analyses%20of%20single%20m.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2287},
rating = {0}
}

@article{Pletcher:2004p265,
author = {Mark J Pletcher and Jeffrey A Tice and Michael Pignone and Charles McCulloch and Tracy Q Callister and Warren S Browner},
journal = {BMC Med},
title = {What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk},
abstract = {BACKGROUND: The coronary artery calcium (CAC) score is an independent predictor of coronary heart disease. We sought to combine information from the CAC score with information from conventional cardiac risk factors to produce post-test risk estimates, and to determine whether the score may add clinically useful information. METHODS: We measured the independent cross-sectional associations between conventional cardiac risk factors and the CAC score among asymptomatic persons referred for non-contrast electron beam computed tomography. Using the resulting multivariable models and published CAC score-specific relative risk estimates, we estimated post-test coronary heart disease risk in a number of different scenarios. RESULTS: Among 9341 asymptomatic study participants (age 35-88 years, 40% female), we found that conventional coronary heart disease risk factors including age, male sex, self-reported hypertension, diabetes and high cholesterol were independent predictors of the CAC score, and we used the resulting multivariable models for predicting post-test risk in a variety of scenarios. Our models predicted, for example, that a 60-year-old non-smoking non-diabetic women with hypertension and high cholesterol would have a 47% chance of having a CAC score of zero, reducing her 10-year risk estimate from 15% (per Framingham) to 6-9%; if her score were over 100, however (a 17% chance), her risk estimate would be markedly higher (25-51% in 10 years). In low risk scenarios, the CAC score is very likely to be zero or low, and unlikely to change management. CONCLUSION: Combining information from the CAC score with information from conventional risk factors can change assessment of coronary heart disease risk to an extent that may be clinically important, especially when the pre-test 10-year risk estimate is intermediate. The attached spreadsheet makes these calculations easy.},
affiliation = {Department of Epidemiology and Biostatistics, University of California, San Francisco 500 Parnassus Ave, MU 420 West, Box 0560, San Francisco, CA 94143-0560, USA. mpletcher@epi.ucsf.edu},
pages = {31},
volume = {2},
year = {2004},
month = {Aug},
language = {eng},
keywords = {Male, Risk Assessment, Humans, Hypertension, Aged: 80 and over, Female, Hypercholesterolemia, Calcinosis, Diabetic Angiopathies, Adult, Aged, Tomography: X-Ray Computed, Regression Analysis, Middle Aged, Coronary Disease, Risk Factors, Sex Factors, Age Factors},
date-added = {2010-01-03 11:12:38 +0100},
date-modified = {2010-01-03 11:12:38 +0100},
doi = {10.1186/1741-7015-2-31},
pii = {1741-7015-2-31},
pmid = {15327691},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Pletcher-2004-BMC%20Med_What%20does%20my%20patient.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p265},
rating = {0}
}

@article{Nassar:2009p1362,
author = {Natasha Nassar and Glenys Dixon and Jenny Bourke and Carol Bower and Emma Glasson and Nick de Klerk and Helen Leonard},
journal = {Int J Epidemiol},
title = {Autism spectrum disorders in young children: effect of changes in diagnostic practices},
abstract = {BACKGROUND: It is unclear whether the increase in autism over the past two decades is a real increase or due to changes in diagnosis and ascertainment of autism spectrum disorders (ASDs), which include autism, Asperger syndrome and pervasive developmental disorder not otherwise specified (PDD-NOS). The aim of this study was to examine the trends in ASD over time in Western Australia (WA) and the possible effects and contribution of changes in diagnostic criteria, age at diagnosis, eligibility for service provision based on ASD diagnoses and changes in diagnostic practices. METHODS: A population-based study was conducted among the cohort of children born in WA between 1983 and 1999 and diagnosed with ASD between the age of 2 and 8 years up to December 31, 2004. The trend in ASD diagnosis over the study period was assessed by investigating birth cohort and period effects, and examining whether these were modified by age of diagnosis. ASD diagnosis corresponding with changes in diagnostic criteria, funding and service provision over time were also investigated. A subgroup analysis of children aged <or=5 years was also conducted to examine trends in the incidence and age of diagnosis of ASD and intellectual disability (ID) and to investigate the role of changes in diagnostic practices. RESULTS: The overall prevalence of ASD among children born between 1983 and 1999 and diagnosed by age 8 was 30 per 10,000 births with the prevalence of autism comprising 21 per 10,000 births. The prevalence of ASD increased by 11.9% per annum, from 8 cases per 10,000 births in 1983 to 46 cases per 10,000 births in 1999. The annual incidence of ASD, based on newly diagnosed ASD cases in each year from 1985 to 2002, increased over the study period. The increase in incidence of ASD appeared to coincide with changes in diagnostic criteria and availability of funding and services in WA, particularly for children aged <5 years. The age-specific rates of autism and PDD-NOS increased over time and the median age of diagnosis for autism decreased from 4 to 3 years of age throughout the 1990s. For children aged <or=5 years the incidence of ASD diagnosis increased significantly from 1992, with an average annual increase of 22%. Similar findings were found for autism. In the corresponding years the incidence of diagnosis of severe ID fell by 10% per annum and mild-moderate ID increased by 3% per annum. CONCLUSIONS: The rise in incidence of all types of ASDs by year of diagnosis appears to be related to changes in diagnostic and service provision practices in WA. In children aged <or=5 years, diagnosis of severe ID decreased, but mild-moderate ID increased during the study period. A true increase in ASD cannot be ruled out.},
affiliation = {Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, West Perth, WA, Australia.},
number = {5},
pages = {1245--54},
volume = {38},
year = {2009},
month = {Oct},
language = {eng},
keywords = {Asperger Syndrome, Diagnosis: Differential, Prevalence, Practice Guidelines as Topic, Male, Female, Delivery of Health Care, Western Australia, Medical Record Linkage, Child: Preschool, Child, Humans, Autistic Disorder},
date-added = {2010-01-07 11:56:59 +0100},
date-modified = {2010-01-07 11:56:59 +0100},
doi = {10.1093/ije/dyp260},
pii = {dyp260},
pmid = {19737795},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Nassar-2009-Int%20J%20Epidemiol_Autism%20spectrum%20diso.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1362},
rating = {0}
}

@article{Mares:2008p12082,
author = {M Mares},
journal = {Computer Science Review},
title = {The saga of minimum spanning trees},
abstract = {This article surveys the many facets of the Minimum Spanning Tree problem. We follow the history of the problem since the first polynomial-time solution by Boru ̊vka to the modern algorithms by Chazelle, Pettie and Ramachandran. We study the differences in time complexity dependent on the model of computation chosen and on the availability of random bits. We also briefly touch the dynamic maintenance of the MST and other related problems.},
pages = {165--221},
volume = {2},
year = {2008},
date-added = {2010-05-24 10:58:11 +0200},
date-modified = {2010-05-24 10:58:52 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mares-2008-Computer%20Science%20Review_The%20saga%20of%20minimum.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12082},
rating = {0}
}

@article{Campion:1993p14107,
author = {Michael A Campion and Gina J Medsker and A Catherine Higgs},
journal = {Personnel Psychology},
title = {Relations between work group characteristics and effectiveness: Implications for designing effective work groups},
pages = {823--850},
volume = {46},
year = {1993},
date-added = {2010-08-18 11:23:32 +0200},
date-modified = {2010-08-18 11:26:21 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Campion-1993-Personnel%20Psychology_Relations%20between%20wo.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14107},
rating = {0}
}

@article{Rungtusanatham:1998p4744,
author = {M Rungtusanatham},
journal = {Decision Line},
title = {Let's Not Overlook Content Validity},
pages = {10--13},
year = {1998},
date-added = {2010-02-01 11:37:00 +0100},
date-modified = {2010-02-01 11:38:13 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rungtusanatham-1998-Decision%20Line_Let%E2%80%99s%20Not%20Overlook%20C.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4744},
rating = {0}
}

@article{Olejnik:2000,
author = {S Olejnik and J Algina},
journal = {Contemporary Educational Psychology},
title = {Measures of effect size for comparative studies: Applications, interpretations, and limitations},
pages = {241--286},
volume = {25},
year = {2000},
date-added = {2010-01-10 11:33:21 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2051},
rating = {0}
}

@article{Coolidge:2009p7672,
author = {Frederick L Coolidge and Daniel L Segal and Christa M Coolidge and Frank M Spinath and Juliana Gottschling},
journal = {Behav Genet},
title = {Do Nightmares and Generalized Anxiety Disorder in Childhood and Adolescence have a Common Genetic Origin?},
abstract = {The present study investigated the prevalence and heritability of nightmares and their comorbidity with psychopathology in a sample (N = 1,318) of children, adolescents, and child and adolescent twins ranging in age from 4 to 17 years old. The prevalence of terrible nightmares was estimated to be 6.4%, which is similar to previous studies. There were marginal gender differences in this rate (7.7% for boys; 5.1% in girls), contrary to previous studies that purport higher rates for girls. There was little evidence for prevalence changes across age. Nightmares were highly heritable and attributed to an additive genetic influence (51%) and nonshared environmental effects (49%). There was little evidence for a shared genetic correlation for nightmares and generalized waking anxiety (Overanxious Disorder of Childhood). There was also a substantial and pervasive comorbid psychopathology for those parents who reported Strongly True on Item 59: My child has terrible nightmares on the 200-item parent-as-respondent, Coolidge Personality and Neuropsychological Inventory. Issues in estimating prevalence rates of nightmares were identified.},
affiliation = {Psychology Department, University of Colorado at Colorado Springs, P.O. Box 7150, Colorado Springs, CO, 80933-7150, USA, fcoolidg@uccs.edu.},
pages = {},
year = {2009},
month = {Nov},
language = {ENG},
date-added = {2010-03-15 23:45:44 +0100},
date-modified = {2010-07-29 20:09:07 +0200},
doi = {10.1007/s10519-009-9310-z},
pmid = {19902346},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Coolidge-2009-Behav%20Genet_Do%20Nightmares%20and%20Ge.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7672},
rating = {3}
}

@article{Petry:2002p9633,
author = {Nancy M Petry and Kris N Kirby and Henry R Kranzler},
journal = {J Stud Alcohol},
title = {Effects of gender and family history of alcohol dependence on a behavioral task of impulsivity in healthy subjects},
abstract = {OBJECTIVE: Substance misusers are often considered impulsive, but it is unclear whether impulsivity precedes substance misuse or develops as a consequence of it. Because alcohol dependence has a clear familial component, a study comparing impulsivity in nonaffected individuals who differ with respect to paternal history of alcohol dependence may provide evidence of familial vulnerability to impulsivity. METHOD: 122 healthy individuals participated, none of whom misused alcohol or drugs; 58 were paternal history positive (PHP) and 64 were paternal history negative (PHN) for alcohol dependence. The paternal-history groups were balanced on gender, and the four paternal-history-by-gender groups were comparable with respect to demographic features. Participants were offered choices between monetary rewards (e.g., {\$}34) available immediately and larger rewards (e.g., {\$}50) available after delays ranging from 1 week to 6 months. This task measures a construct of impulsivity by assessing the rates at which individuals discount rewards delayed in time. RESULTS: Although discount rates in PHP men did not differ reliably from those in PHN men, PHP women had higher discount rates than PHN women. Post hoc contrasts revealed that PHN women had lower discount rates than the other three groups. Similar results were obtained when age, education, socioeconomic status, and scores on a measure of sociopathy were used as covariates. CONCLUSIONS: Paternal history of alcohol dependence is associated with greater discount rates among women. The lack of an effect for men may suggest different mechanisms by which risk is transmitted from alcohol-dependent fathers to daughters compared with sons. Further research examining these relations and the implications that delay discounting has for drinking and related behaviors is warranted.},
affiliation = {Department of Psychiatry, University of Connecticut Health Center, Farmington 06030-3944, USA. petry@psychiatry.uchc.edu},
number = {1},
pages = {83--90},
volume = {63},
year = {2002},
month = {Jan},
language = {eng},
keywords = {Adult, Sex Characteristics, Male, Female, Alcoholism, Chi-Square Distribution, Reward, Humans, Impulsive Behavior, Statistics: Nonparametric, Choice Behavior, Analysis of Variance},
date-added = {2010-03-25 14:47:46 +0100},
date-modified = {2010-03-25 14:47:46 +0100},
pmid = {11925063},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9633},
rating = {0}
}

@article{Jonsson:2004p10518,
author = {Erik G J{\"o}nsson and Jessica Bah and Jonas Melke and Rami Abou Jamra and Johannes Schumacher and Lars Westberg and Roland Ivo and Sven Cichon and Peter Propping and Markus M N{\"o}then and Elias Eriksson and G{\"o}ran C Sedvall},
journal = {BMC Psychiatry},
title = {Monoamine related functional gene variants and relationships to monoamine metabolite concentrations in CSF of healthy volunteers},
abstract = {BACKGROUND: Concentrations of monoamine metabolites in human cerebrospinal fluid (CSF) have been used extensively as indirect estimates of monoamine turnover in the brain. CSF monoamine metabolite concentrations are partly determined by genetic influences. METHODS: We investigated possible relationships between DNA polymorphisms in the serotonin 2C receptor (HTR2C), the serotonin 3A receptor (HTR3A), the dopamine D4 receptor (DRD4), and the dopamine beta-hydroxylase (DBH) genes and CSF concentrations of 5-hydroxyindolacetic acid (5-HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG) in healthy volunteers (n = 90). RESULTS: The HTR3A 178 C/T variant was associated with 5-HIAA levels (p = 0.02). The DBH-1021 heterozygote genotype was associated with 5-HIAA (p = 0.0005) and HVA (p = 0.009) concentrations. Neither the HTR2C Cys23Ser variant, nor the DRD4 -521 C/T variant were significantly associated with any of the monoamine metabolites. CONCLUSIONS: The present results suggest that the HTR3A and DBH genes may participate in the regulation of dopamine and serotonin turnover rates in the central nervous system.},
affiliation = {Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institutet, Stockholm, Sweden. erikj@ks.se},
pages = {4},
volume = {4},
year = {2004},
month = {Mar},
language = {eng},
keywords = {Methoxyhydroxyphenylglycol, Hydroxyindoleacetic Acid, Adult, Longitudinal Studies, Homovanillic Acid, Receptors: Dopamine D4, Humans, Genotype, Serotonin, Middle Aged, Receptor: Serotonin: 5-HT2C, Gene Frequency, Genetic Variation, Brain, Polymorphism: Genetic, Male, Receptors: Serotonin: 5-HT3, Dopamine, Receptors: Dopamine D2, Female, Dopamine beta-Hydroxylase, Psychiatric Status Rating Scales},
date-added = {2010-04-07 11:20:13 +0200},
date-modified = {2010-04-07 11:20:13 +0200},
doi = {10.1186/1471-244X-4-4},
pii = {1471-244X-4-4},
pmid = {15102340},
URL = {http://www.biomedcentral.com/1471-244X/4/4},
local-url = {file://localhost/Users/chl/Dropbox/Papers/J%C3%B6nsson-2004-BMC%20Psychiatry_Monoamine%20related%20fu.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10518},
rating = {0}
}

@article{Vivien:2004p12018,
author = {M Vivien and R Sabatier},
journal = {Computational Statistics},
title = {A generalization of STATIS-ACT strategy: DO-ACT for two multiblocks tables},
abstract = {A new strategy is introduced for analyzing two multiblocks tables: DO-ACT. This method is closely related to the STATIS (or ACT) methodology and the Tucker inter-battery method. The length of two multiblocks are not necessarily the same and the optimal solution obtained is that of a global optimization problem. The advantage of using DO-ACT is that the 􏱱rst step provides a summary of the two multiblocks tables, in the second step two optimal representations (one for each multiblock) of the observations can be plotted and in the third step a global description of each table of each multiblock can be made. An example of DO-ACT performance is illustrated with a real data set. The program implementing the method has been developed using the S-Plus 6:0J (2000) language.},
pages = {155--171},
volume = {46},
year = {2004},
date-added = {2010-05-23 22:44:06 +0200},
date-modified = {2010-07-29 19:24:31 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Vivien-2004-Computational%20Statistics_A%20generalization%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12018},
rating = {0}
}

@article{Raman:2009p5894,
author = {S Raman and T J Fuchs and P J Wild and E Dahl and V Roth},
journal = {Proceedings of the 26th International Conference on Machine Learning},
title = {The Bayesian Group-Lasso for Analyzing Contingency Tables},
abstract = {Group-Lasso estimators, useful in many applica- tions, suffer from lack of meaningful variance es- timates for regression coefficients. To overcome such problems, we propose a full Bayesian treat- ment of the Group-Lasso, extending the stan- dard Bayesian Lasso, using hierarchical expan- sion. The method is then applied to Poisson mod- els for contingency tables using a highly efficient MCMC algorithm. The simulated experiments validate the performance of this method on arti- ficial datasets with known ground-truth. When applied to a breast cancer dataset, the method demonstrates the capability of identifying the dif- ferences in interactions patterns of marker pro- teins between different patient groups.},
year = {2009},
date-added = {2010-02-17 21:08:05 +0100},
date-modified = {2010-02-17 21:12:30 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Raman-2009-Proceedings%20of%20the%2026th%20International%20Conference%20on%20Machine%20Learning_The%20Bayesian%20Group-L.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5894},
rating = {0}
}

@article{vanRoon:2010p5085,
author = {Dominique van Roon and Karen Caeyenberghs and Stephan P Swinnen and Bouwien C M Smits-Engelsman},
journal = {Res Dev Disabil},
title = {Children with a learning disorder show prospective control impairments during visuomanual tracking},
abstract = {To examine whether children with a learning disorder (LD) are able to use prospective motor control, 30 children with LD (mean age 8 years and 11 months) and an age- and gender-matched control group were asked to smoothly track an accelerating dot presented on a monitor by moving an electronic pen on a digitizer. Children with LD performed worse than controls: the number of drawn circles was smaller, the maximum target velocity lower, and the number of submovements was higher. It is suggested that a decreased ability to predict the movement of the target leads to impaired visuomanual tracking in children with LD. Furthermore, children with LD did not improve from the 1st to the 2nd trial, possibly as a result of slower visuomotor adaptation processes.},
affiliation = {Research Center for Movement Control and Neuroplasticity, Department of Biomedical Kinesiology, Katholieke Universiteit Leuven, Heverlee, Belgium. d.vanroon@cbs.nl},
number = {1},
pages = {195--202},
volume = {31},
year = {2010},
month = {Jan},
language = {eng},
keywords = {Male, Problem Solving, Psychomotor Performance, Motion Perception, Female, Acceleration, Humans, Child, Neuropsychological Tests, Practice (Psychology), Education: Special, Pattern Recognition: Visual, Attention, Concept Formation, Learning Disorders, Pursuit: Smooth, Motor Skills Disorders, Orientation},
date-added = {2010-02-05 20:14:38 +0100},
date-modified = {2010-02-05 20:14:44 +0100},
doi = {10.1016/j.ridd.2009.09.004},
pii = {S0891-4222(09)00148-6},
pmid = {19819108},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5085},
rating = {4}
}

@article{Tibshirani1996,
author = {R Tibshirani},
journal = {Journal of the Royal Society, Serie B},
title = {Regression shrinkage and selection via the lasso},
pages = {267--288},
volume = {58},
year = {1996},
date-added = {2010-01-12 14:26:48 +0100},
date-modified = {2010-07-29 19:38:24 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2519},
rating = {0}
}

@article{Shifman:2008p11374,
author = {Sagiv Shifman and Martina Johannesson and Michal Bronstein and Sam X Chen and David A Collier and Nicholas J Craddock and Kenneth S Kendler and Tao Li and Michael O'Donovan and F Anthony O'Neill and Michael J Owen and Dermot Walsh and Daniel R Weinberger and Cuie Sun and Jonathan Flint and Ariel Darvasi},
journal = {PLoS Genet},
title = {Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women},
abstract = {Sex differences in schizophrenia are well known, but their genetic basis has not been identified. We performed a genome-wide association scan for schizophrenia in an Ashkenazi Jewish population using DNA pooling. We found a female-specific association with rs7341475, a SNP in the fourth intron of the reelin (RELN) gene (p = 2.9 x 10(-5) in women), with a significant gene-sex effect (p = 1.8 x 10(-4)). We studied rs7341475 in four additional populations, totaling 2,274 cases and 4,401 controls. A significant effect was observed only in women, replicating the initial result (p = 2.1 x 10(-3) in women; p = 4.2 x 10(-3) for gene-sex interaction). Based on all populations the estimated relative risk of women carrying the common genotype is 1.58 (p = 8.8 x 10(-7); p = 1.6 x 10(-5) for gene-sex interaction). The female-specific association between RELN and schizophrenia is one of the few examples of a replicated sex-specific genetic association in any disease.},
affiliation = {Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kindgdom. sagiv@vms.huji.ac.il},
number = {2},
pages = {e28},
volume = {4},
year = {2008},
month = {Feb},
language = {eng},
keywords = {Serine Endopeptidases, Odds Ratio, Male, Introns, Case-Control Studies, Gene Frequency, Female, Risk Factors, Genome: Human, Extracellular Matrix Proteins, Adult, Sex Characteristics, Alleles, Asian Continental Ancestry Group, Humans, Schizophrenia, Nerve Tissue Proteins, Jews, European Continental Ancestry Group, Genetic Predisposition to Disease, Polymorphism: Single Nucleotide, Cell Adhesion Molecules: Neuronal, Middle Aged, Genetic Variation},
date-added = {2010-04-26 23:10:42 +0200},
date-modified = {2010-04-26 23:10:45 +0200},
doi = {10.1371/journal.pgen.0040028},
pii = {07-PLGE-RA-0891},
pmid = {18282107},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Shifman-2008-PLoS%20Genet_Genome-wide%20associat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11374},
rating = {4}
}

@article{MacDonald:1999p3054,
author = {V M MacDonald and Thomas M Achenbach},
journal = {J Am Acad Child Adolesc Psychiatry},
title = {Attention problems versus conduct problems as 6-year predictors of signs of disturbance in a national sample},
abstract = {OBJECTIVE: To test whether attention problems predicted different signs of disturbance than conduct problems over 3 and 6 years. METHOD: Gender-specific criteria for deviance on parents' ratings of attention versus conduct problems were tested as predictors of interview-reported signs of disturbance in a national sample first assessed at ages 4 to 16 years. RESULTS: Males and females deviant on both attention and conduct problems showed higher rates of several signs of disturbance than did those deviant on only one type of problem. Subjects deviant only on conduct problems showed higher rates of several signs than did controls, whereas those deviant only on attention problems exceeded controls mainly on special education services. Unaggressive "delinquent" conduct problems predicted dropping out of school, unwed pregnancy, and total signs for both genders during transitions to adulthood. CONCLUSIONS: Attention problems predict receipt of special education but contribute much less than conduct problems to predicting other signs of disturbance. Differential assessment of aggressive versus unaggressive conduct problems can improve prediction, as can gender specificity in setting criteria for deviance and in testing outcomes.},
affiliation = {Chittenden South School District, Hinesburg, VT, USA.},
number = {10},
pages = {1254--61},
volume = {38},
year = {1999},
month = {Oct},
language = {eng},
keywords = {Sex Factors, Predictive Value of Tests, Social Problems, Conduct Disorder, Adult, Child Behavior Disorders, Pregnancy, Child: Preschool, Prospective Studies, Case-Control Studies, Adolescent, United States, Odds Ratio, Humans, Female, Age Factors, Psychiatric Status Rating Scales, Logistic Models, Attention Deficit Disorder with Hyperactivity, Child, Forecasting, Interview: Psychological},
date-added = {2010-01-14 11:26:37 +0100},
date-modified = {2010-07-29 20:15:47 +0200},
pmid = {10517058},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3054},
rating = {0}
}

@article{Fayers:2010p1775,
author = {P Fayers},
title = {IRT: The way forward},
date-added = {2010-01-09 21:42:03 +0100},
date-modified = {2010-01-09 21:42:29 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fayers--_IRT%20The%20way%20forward.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1775},
rating = {0}
}

@article{Maurex:2010p7794,
author = {L Maurex and G Zaboli and A Ohman and M Asberg and R Leopardi},
journal = {Eur Psychiatry},
title = {The serotonin transporter gene polymorphism (5-HTTLPR) and affective symptoms among women diagnosed with borderline personality disorder},
abstract = {Gene variants of the serotonin transporter have been associated with vulnerability to affective disorders. In particular, the presence of one or two copies of the short (s) allele of the 5-HTTLPR polymorphism has been associated with reduced serotonin transporter expression and function, and vulnerability to affective disorders. To test for an association between variants of the serotonin transporter gene polymorphism (5-HTTLPR) and relevant clinical features of borderline personality disorder (BPD), a psychiatric disorder with symptoms characteristic for serotonin dysfunction, 77 women with BPD were genotyped in the 5-HTTLPR polymorphism. They rated their subjective experience of borderline-specific, depressive, anxious and obsessive-compulsive symptoms, and were interviewed about lifetime incidence of suicide attempts and self-harming acts. Carriers of two s alleles of the 5-HTTLPR reported more symptoms of borderline, depression, anxiety and obsessive-compulsive behaviours, but not of suicidal and self-injury behaviour, compared to carriers of a long (l) allele. This indicates that the 5-HTTLPR ss homozygous genotype might influence serotonin function affecting susceptibility to both borderline-specific, depressive, anxious and obsessive-compulsive symptoms in BPD, and leading to a more severe symptomatology related to these clinical features. Further, this suggests that 5-HTT gene variants may not be as influential on suicidal and self-injury behaviour in BPD.},
affiliation = {Section of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden. Liselotte.Maurex@ki.se},
number = {1},
pages = {19--25},
volume = {25},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-03-17 20:59:44 +0100},
date-modified = {2010-03-17 20:59:49 +0100},
doi = {10.1016/j.eurpsy.2009.05.001},
pii = {S0924-9338(09)00077-7},
pmid = {19699062},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Maurex-2010-Eur%20Psychiatry_The%20serotonin%20transp.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7794},
rating = {4}
}

@article{Yang:2007p4742,
author = {Frances M Yang and Richard N Jones},
journal = {Journal of Clinical Epidemiology},
title = {Center for Epidemiologic Studies-Depression Scale (CES-D) item response bias found with Mantel-Haenszel method was successfully replicated using latent variable modeling},
abstract = {OBJECTIVE: This study reexamines findings reported by Cole et al. of item response bias in the Center for Epidemiologic Studies-Depression (CES-D) scale by age, gender, and race. We use an item response theory-based latent variable conditioning approach. STUDY DESIGN AND SETTING: We used the multiple indicators, multiple causes (MIMIC) model framework to estimate measurement bias in the CES-D responses of participants in the New Haven Established Populations for the Epidemiologic Studies of the Elderly study (N=2,340). RESULTS: Measurement bias attributable to race was significant for the following two CES-D items: people "are unfriendly" and "dislike me". The proportional odds of a higher-category response by blacks relative to whites on these items were 2.35 (95% confidence interval [CI]: 1.65, 3.36) and 3.11 (95% CI: 2.04, 4.76), respectively. The proportional odds were higher among women (2.03 [95% CI: 1.35, 3.06]) relative to men for the CES-D item "crying." CONCLUSION: Our findings confirm that three items on the CES-D show strong evidence of item response bias. The MIMIC model is preferable to the Mantel-Haenszel approach because it conditions on a latent variable, although the effect estimates can also be interpreted using a proportional odds framework.},
affiliation = {Institute for Aging Research, Hebrew SeniorLife, Boston, MA 02131, USA. francesyang@hrca.harvard.edu},
number = {11},
pages = {1195--200},
volume = {60},
year = {2007},
month = {Nov},
language = {eng},
keywords = {Connecticut, Humans, Aged, Male, African Continental Ancestry Group, Depression, European Continental Ancestry Group, Age Distribution, Models: Statistical, Sex Distribution, Female, Psychiatric Status Rating Scales, Bias (Epidemiology)},
date-added = {2010-02-01 11:36:01 +0100},
date-modified = {2010-02-01 11:36:02 +0100},
doi = {10.1016/j.jclinepi.2007.02.008},
pii = {S0895-4356(07)00065-0},
pmid = {17938063},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Yang-2007-Journal%20of%20Clinical%20Epidemiology_Center%20for%20Epidemiol.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4742},
rating = {0}
}

@article{Joseph:2010p4097,
author = {D A Joseph},
title = {Learning an Internet Coordinate System: PCA versus Factor Analysis},
abstract = {A large number of networking applications require knowledge of packet round trip times to different machines on the Internet. We use a set of N bea- cons to construct an N-dimensional coordinate sys- tem, where N is in the range 20 to 30. The delay between two machines is the Euclidean Distance between their coordinates. Principal Component Analysis (PCA) and Factor Analysis (FA) are used to reduce the N-dimensional coordinate system to a much smaller K-dimensional space, where K is in the range 3 to 5. Using data collected from real world networks, we show that dimensionality reduction preserves network topology information. We observe that PCA outperforms FA in estima- tion accuracy as well as in computational overhead and explore the reasons for this mismatch.},
date-added = {2010-01-19 23:29:08 +0100},
date-modified = {2010-01-19 23:29:33 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Joseph--_Learning%20an%20Internet.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4097},
rating = {0}
}

@article{Steiger:2004p2433,
author = {J H Steiger},
journal = {Psychological Methods},
title = {Beyond the F Test: Effect Size Confidence Intervals and Tests of Close Fit in the Analysis of Variance and Contrast Analysis},
abstract = {This article presents confidence interval methods for improving on the standard F tests in the balanced, completely between-subjects, fixed-effects analysis of variance. Exact confidence intervals for omnibus effect size measures, such as 􏰜2 and the root-mean-square standardized effect, provide all the information in the traditional hypothesis test and more. They allow one to test simultaneously whether overall effects are (a) zero (the traditional test), (b) trivial (do not exceed some small value), or (c) nontrivial (definitely exceed some minimal level). For situations in which single-degree-of-freedom contrasts are of primary interest, exact confi- dence interval methods for contrast effect size measures such as the contrast correlation are also provided.},
number = {2},
pages = {164--182},
volume = {9},
year = {2004},
date-added = {2010-01-11 23:41:50 +0100},
date-modified = {2010-01-11 23:42:39 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Steiger-2004-Psychological%20Methods_Beyond%20the%20F%20Test%20E.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2433},
rating = {0}
}

@article{BenAkiva:1999p6663,
author = {M Ben-Akiva and J Walker and A T Bernardino and D A Gopinath and T Morikawa and A Polydoropoulou},
title = {Integration of Choice and Latent Variable Models},
abstract = {This paper presents a general methodology and framework for including latent variables---in particular, attitudes and perceptions---in choice models. This is something that has long been deemed necessary by behavioral researchers, but is often either ignored in statistical models, introduced in less than optimal ways (e.g., sequential estimation of a latent variable model then a choice model, which produces inconsistent estimates), or introduced for a narrowly defined model structure. The paper is focused on the use of psychometric data to explicitly model attitudes and perceptions and their influences on choices. The methodology requires the estimation of an integrated multi-equation model consisting of a discrete choice model and the latent variable model's structural and measurement equations. The integrated model is estimated simultaneously using a maximum likelihood estimator, in which the likelihood function includes complex multi-dimensional integrals. The methodology is applicable to any situation in which one is modeling choice behavior (with any type and combination of choice data) where (1) there are important latent variables that are hypothesized to influence the choice and (2) there exist indicators (e.g., responses to survey questions) for the latent variables. Three applications of the methodology provide examples and demonstrate the flexibility of the approach, the resulting gain in explanatory power, and the improved specification of discrete choice models.},
year = {1999},
date-added = {2010-03-05 22:03:47 +0100},
date-modified = {2010-03-05 22:04:54 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ben-Akiva-1999-_Integration%20of%20Choic.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6663},
rating = {0}
}

@article{Untas:2009p8705,
author = {Aur{\'e}lie Untas and Maider Aguirrezabal and Philippe Chauveau and Eric Leguen and Christian Combe and Nicole Rascle},
journal = {Nephrol Ther},
title = {[Anxiety and depression in hemodialysis: validation of the Hospital Anxiety and Depression Scale (HADS)]},
abstract = {Anxiety and depression are considered as frequent disorders in end-stage renal disease patients. However studies on this topic are almost nonexistent in France. The Hospital Anxiety and Depression Scale (HADS, Zigmond {\&} Snaith, 1983) is a well-used instrument in the international literature. Fast and easy to administer, it measures anxiety and depression symptomatology in physically ill patients. The purpose of the present study was to test the psychometric properties of the scale within a French sample of 207 hemodialysis patients. Exploratory factor analysis yielded two factors: anxiety and depression. Further analysis showed that the two factors presented good internal consistency, were significantly correlated to patient's age and quality of life, but were not associated with years on dialysis. Moreover, differences were found for gender and dialysis modality (self-care units versus in center). The results of this study underline the relevance of using the HADS to identify anxiety and depression and confirm the importance to take into account these disorders to enhance patient's quality of life and global care.},
affiliation = {EA 4139, laboratoire de psychologie << sant{\'e} et qualit{\'e} de vie >>, universit{\'e} Victor-Segalen Bordeaux-2, 3, ter place de la Victoire, 33076 Bordeaux cedex, France. aurelie.untas@u-bordeaux2.fr},
number = {3},
pages = {193--200},
volume = {5},
year = {2009},
month = {Jun},
language = {fre},
keywords = {Humans, Depression, Middle Aged, Male, Female, Anxiety, Renal Dialysis, Aged, Questionnaires},
date-added = {2010-03-22 12:00:24 +0100},
date-modified = {2010-03-22 12:00:24 +0100},
doi = {10.1016/j.nephro.2009.01.007},
pii = {S1769-7255(09)00050-9},
pmid = {19346177},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8705},
rating = {0}
}

@article{Koenig:2007p3348,
author = {J A Koenig and J S Roberts},
journal = {Applied Psychological Measurement},
title = {Linking Parameters Estimated With the Generalized Graded Unfolding Model: A Comparison of the Accuracy of Characteristic Curve Methods},
abstract = {Methods for linking item response theory (IRT) parameters are developed for attitude questionnaire responses calibrated with the generalized graded unfolding model (GGUM). One class of IRT linking methods derives the linking coefficients by comparing characteristic curves, and three of these methods---test characteristic curve (TCC), item characteristic curve (ICC), and operating characteristic curve (OCC)---are extended for use with the GGUM. Alternate versions of these methods are developed to produce both symmetric and asymmetric solutions. The adequacy of these methods for use with the GGUM is evaluated in a simulation that varied the distributions of y in the groups to be linked and the number of individuals and anchor items used for linking. All methods performed well under the conditions studied. Statistically significant effects were found for sample size and number of anchor items. It is recommended that choice of linking method should consider the context and intent of the linking.},
number = {6},
pages = {504--524},
volume = {31},
year = {2007},
date-added = {2010-01-15 12:50:00 +0100},
date-modified = {2010-01-15 12:51:06 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Koenig-2007-Applied%20Psychological%20Measurement_Linking%20Parameters%20E.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3348},
rating = {0}
}

@article{Shalom:2009p5102,
author = {Dorit Ben Shalom},
journal = {Neuroscientist},
title = {The medial prefrontal cortex and integration in autism},
abstract = {This article offers a unifying theoretical interpretation of known abnormalities in people with autism spectrum disorders (ASDs) in four psychological domains, namely emotion, memory, sensation-perception, and motor skills. It proposes that in all four domains three levels of processing can be identified: a basic level, an integrative level, and a "logical" or higher-order level. It also notes that in typically developing people, there is evidence that the integrative level is subserved by subregions of the medial prefrontal cortex. The major argument of the article is to propose and argue that the integrative level in all four domains is responsible for common atypicalities in people with ASDs.},
affiliation = {Zlotowski Center for Neuroscience, Ben Gurion University of the Negev, Beer Sheva, Israel. doritb@bgu.ac.il},
number = {6},
pages = {589--98},
volume = {15},
year = {2009},
month = {Dec},
language = {eng},
date-added = {2010-02-05 20:17:15 +0100},
date-modified = {2010-02-05 20:17:15 +0100},
doi = {10.1177/1073858409336371},
pii = {1073858409336371},
pmid = {19617590},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5102},
rating = {0}
}

@article{Jiang:2005p6789,
author = {W Jiang},
title = {Bayesian variable selection for high dimensional generalized linear models},
abstract = {Bayesian variable selection has gained much empirical success re- cently in a variety of applications when the number K of explanatory variables (x1,...,xK) is possibly much larger than the sample size n. For generalized linear models, if most of the xj's have very small effects on the response y, we show that it is possible to use Bayesian vari- able selection to avoid overfitting caused by the curse of dimensionality K >> n. In this approach a suitable prior can be used to choose a few out of the many xj 's to model y, so that the posterior will propose probability densities p that are `often close' to the true density p∗ in some sense. The closeness can be described by a Hellinger distance be- tween p and p∗ that scales at a power very close to n−1/2, which is the `finite-dimensional rate' corresponding to a low dimensional situation. These findings extend some recent work of Jiang (2005) on consistency of Bayesian variable selection for binary classification.},
year = {2005},
date-added = {2010-03-05 22:27:00 +0100},
date-modified = {2010-07-11 09:49:50 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Jiang-2005-_Bayesian%20variable%20se-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6789},
rating = {0}
}

@article{Szantai:2005p9732,
author = {E Szantai and R Szmola and M Sasvari-Szekely and A Guttman and Z Ronai},
journal = {BMC Genet},
title = {The polymorphic nature of the human dopamine D4 receptor gene: a comparative analysis of known variants and a novel 27 bp deletion in the promoter region},
abstract = {BACKGROUND: The human dopamine D4 receptor (DRD4) is a candidate gene of great interest in molecular studies of human personality and psychiatric disorders. This gene is unique in having an exceptionally high amount of polymorphic sites both in the coding and in the promoter region. RESULTS: We report the identification of a new 27 bp deletion starting 524 bp upstream of the initiation codon (27 bp del) of the dopamine D4 receptor (DRD4) gene, in the close vicinity of the -521C>T SNP. The presence of the 27 bp deletion leads to the misgenotyping of the -616C>G SNP by the Sau96 I RFLP method, thus the genotype determination of the mutation is of additional importance. The frequency of this novel sequence variation is considerably low (allele frequency is = 0.16%), as no homozygotes, and only 3 heterozygote carriers were found in a healthy, unrelated Caucasian sample (N = 955). CONCLUSION: Remarkably, the deleted region contains consensus sequences of binding sites for several known transcription factors, suggesting that the different alleles may affect the transcriptional regulation of the gene. A comparison of methods and results for the allelic variations of the DRD4 gene in various ethnic groups is also discussed, which has a high impact in psychiatric genetic studies.},
affiliation = {Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary. szantai@puskin.sote.hu},
pages = {39},
volume = {6},
year = {2005},
month = {Jan},
language = {eng},
keywords = {Gene Frequency, Humans, Gene Deletion, Receptors: Dopamine D4, Binding Sites, Polymorphism: Genetic, Promoter Regions: Genetic, Transcription Factors},
date-added = {2010-03-25 15:15:32 +0100},
date-modified = {2010-03-25 15:15:32 +0100},
doi = {10.1186/1471-2156-6-39},
pii = {1471-2156-6-39},
pmid = {15985158},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Szantai-2005-BMC%20Genet_The%20polymorphic%20natu.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9732},
rating = {0}
}

@article{Kinney:2006p7715,
author = {S K Kinney and D B Dunson},
title = {Fixed and random effects selection in linear and logistic models},
abstract = {We address the problem of selecting which variables should be included in the fixed and ran- dom components of logistic mixed effects models for correlated data. A fully Bayesian variable selection is implemented using a stochastic search Gibbs sampler to estimate the exact model-averaged posterior distri- bution. This approach automatically identifies subsets of predictors having non-zero fixed effect coefficients or non-zero random effects variance, while allowing uncertainty in the model selection process. Default priors are proposed for the variance components and an efficient parameter expansion Gibbs sampler is de- veloped for posterior computation. The approach is illustrated using simulated data and an epidemiologic example.},
year = {2006},
date-added = {2010-03-17 20:47:25 +0100},
date-modified = {2010-03-17 20:48:05 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kinney-2006-_Fixed%20and%20random%20eff.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7715},
rating = {0}
}

@article{Pjrek:2007p9958,
author = {Edda Pjrek and Dietmar Winkler and Nicole Praschak-Rieder and Matth{\"a}us Willeit and J{\"u}rgen Stastny and Anastasios Konstantinidis and Siegfried Kasper},
journal = {European archives of psychiatry and clinical neuroscience},
title = {Season of birth in siblings of patients with seasonal affective disorder. A test of the parental conception habits hypothesis},
abstract = {Recently we have published a report on seasonally varying birth rates in 553 patients with seasonal affective disorder (SAD). The present study is aimed to test the hypothesis of an idiosyncratic seasonal conception pattern of the parents of these patients to explain this phenomenon. We conducted a telephone interview with the patients to obtain information on the birth data of their siblings. Using the method of chart review to acquire information on the family history of our patients, we excluded those siblings with psychiatric disorders. We first compared the birth months and the quarters of birth of 435 healthy siblings with the general population. Secondly, we compared the birth distribution of the index SAD patients with that of their siblings. There was a significant deviation between the birth distribution of the siblings and the general population calculated on a monthly basis (p = 0.044). When comparing quarters we found less births than expected in the first (-14.1%) and fourth quarter of the year (-15.1%) and an excess of births in the second (+7.7%) and third quarter (+21.1%; p = 0.018). There were no significant differences between the group of SAD patients and their siblings regarding their birth patterns as calculated by months (p = 0.848) or quarters (p = 0.320). Our study provides support for the hypothesis of specific parental conception habits underlying the birth seasonality in SAD. Further research could be conducted in non-seasonal depression as there is still a lack of studies on seasonality of birth in affective disorders.},
affiliation = {Department of Psychiatry and Psychotherapy, Medical University of Vienna, W{\"a}hringer G{\"u}rtel 18-20, 1090 Vienna, Austria. edda.pjrek@meduniwien.ac.at},
number = {7},
pages = {378--82},
volume = {257},
year = {2007},
month = {Oct},
language = {eng},
keywords = {Psychiatric Status Rating Scales, Female, Middle Aged, Humans, Austria, Male, Chi-Square Distribution, Birth Rate, Seasons, Cohort Studies, Seasonal Affective Disorder, Siblings},
date-added = {2010-03-31 16:11:41 +0200},
date-modified = {2010-03-31 16:11:41 +0200},
doi = {10.1007/s00406-007-0720-8},
pmid = {17902009},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Pjrek-2007-European%20archives%20of%20psychiatry%20and%20clinical%20neuroscience_Season%20of%20birth%20in%20s.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9958},
rating = {0}
}

@article{Clayton:2007p2308,
author = {David Clayton and Hin-Tak Leung},
journal = {Hum Hered},
title = {An R package for analysis of whole-genome association studies},
abstract = {OBJECTIVE: To provide data classes and methods to facilitate the analysis of whole genome association studies in the R language for statistical computing. METHODS: We have implemented data classes in which each genotype call is stored as a single byte. At this density, data for single chromosomes derived from large studies and new high-throughput gene chip platforms can be handled in memory. We use the object-oriented programming model introduced with version 4 of the S-plus package, usually termed 'S4 methods'. RESULTS: At the current state of development the package only supports population-based studies, although we would hope to provide support for family-based studies soon. Both quantitative and qualitative phenotypes may be analysed. Flexible association testing functions are provided which can carry out single SNP tests which control for potential confounding by quantitative and qualitative covariates. Tests involving several SNPs taken together as 'tags' are also supported. Efficient calculation of pair-wise linkage disequilibrium measures is implemented and data input functions include a function which can download data directly from the international HapMap project website.},
affiliation = {Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. david.clayton@cimr.cam.ac.uk},
number = {1},
pages = {45--51},
volume = {64},
year = {2007},
month = {Jan},
language = {eng},
keywords = {linkage disequilibrium, Genotype, Phenotype, Genome: Human, Models: Genetic, Humans, Software, Polymorphism: Single Nucleotide, Databases: Genetic},
date-added = {2010-01-10 12:22:54 +0100},
date-modified = {2010-01-10 12:22:54 +0100},
doi = {10.1159/000101422},
pii = {000101422},
pmid = {17483596},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Clayton-2007-Hum%20Hered_An%20R%20package%20for%20ana.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2308},
rating = {0}
}

@article{Zou2005,
author = {H Zou and T Hastie},
journal = {Journal of the Royal Society, Serie B},
title = {Regression and variable selection via the elastic net},
pages = {301--320},
volume = {67},
year = {2005},
date-added = {2010-01-12 14:26:48 +0100},
date-modified = {2010-07-29 19:38:24 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2525},
rating = {0}
}

@article{Ahern:1982p12642,
author = {F M Ahern and R C Johnson and J R Wilson and G E McClearn and S G Vandenberg},
journal = {Behav Genet},
title = {Family resemblances in personality},
number = {3},
pages = {261--80},
volume = {12},
year = {1982},
month = {May},
language = {eng},
keywords = {Female, Adult, Male, Twins: Dizygotic, Adolescent, Twins: Monozygotic, Middle Aged, Humans, Phenotype, Pregnancy, Personality},
date-added = {2010-06-15 22:39:58 +0200},
date-modified = {2010-07-29 20:09:06 +0200},
pmid = {6889860},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ahern-1982-Behav%20Genet_Family%20resemblances.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12642},
rating = {4}
}

@article{Faul:2009p4294,
author = {F Faul and E Erdfelder and A Buchner and A G Lang},
journal = {Behavior research methods},
title = {Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses},
abstract = {G*Power is a free power analysis program for a variety of statistical tests. We present extensions and improve- ments of the version introduced by Faul, Erdfelder, Lang, and Buchner (2007) in the domain of correlation and regression analyses. In the new version, we have added procedures to analyze the power of tests based on (1) single-sample tetrachoric correlations, (2) comparisons of dependent correlations, (3) bivariate linear regres- sion, (4) multiple linear regression based on the random predictor model, (5) logistic regression, and (6) Poisson regression. We describe these new features and provide a brief introduction to their scope and handling.},
number = {4},
pages = {1149--1160},
volume = {41},
year = {2009},
date-added = {2010-01-26 09:26:23 +0100},
date-modified = {2010-07-29 19:18:35 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Faul-2009-Behavior%20research%20methods_Statistical%20power%20an.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4294},
rating = {0}
}

@article{Liang:2008p420,
author = {Faming Liang and Jian Zhang},
journal = {Biometrika},
title = {Estimating the false discovery rate using the stochastic approximation algorithm},
abstract = {Testing of multiple hypotheses involves statistics that are strongly dependent in some appli- cations, but most work on this subject is based on the assumption of independence. We propose a new method for estimating the false discovery rate of multiple hypothesis tests, in which the density of test scores is estimated parametrically by minimizing the Kullback--Leibler distance between the unknown density and its estimator using the stochastic approximation algorithm, and the false discovery rate is estimated using the ensemble averaging method. Our method is applicable under general dependence between test statistics. Numerical comparisons between our method and several competitors, conducted on simulated and real data examples, show that our method achieves more accurate control of the false discovery rate in almost all scenarios.},
affiliation = {Department of Statistics, Texas A{\&}M University, College Station, Texas 77843, U.S.A.},
number = {4},
pages = {961--977},
volume = {95},
year = {2008},
keywords = {False discovery rate, Ensemble averaging, Microarray data analysis, Multiple hypothesis testing, Stochastic approximation},
date-added = {2010-01-03 12:13:56 +0100},
date-modified = {2010-01-03 12:15:52 +0100},
doi = {10.1093/biomet/asn036},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Liang-2008-Biometrika_Estimating%20the%20false.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p420},
rating = {0}
}

@phdthesis{Courville:2004,
author = {T G Courville},
journal = {PhD Thesis},
title = {An empirical comparison of item response theory and classical test theory item/person statistics},
affiliation = {Texas A{\&}M University},
year = {2004},
month = {Aug},
date-added = {2010-01-10 11:33:19 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Courville-2004-PhD%20Thesis_An%20empirical%20compari.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2109},
rating = {0}
}

@article{Matise:2007p4933,
author = {Tara C Matise and Fang Chen and Wenwei Chen and Francisco M De La Vega and Mark Hansen and Chunsheng He and Fiona C L Hyland and Giulia C Kennedy and Xiangyang Kong and Sarah S Murray and Janet S Ziegle and William C L Stewart and Steven Buyske},
journal = {Genome Res},
title = {A second-generation combined linkage physical map of the human genome},
abstract = {We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.},
affiliation = {Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA. matise@biology.rutgers.edu},
number = {12},
pages = {1783--6},
volume = {17},
year = {2007},
month = {Dec},
language = {eng},
keywords = {Genotype, Genetic Markers, Polymorphism: Single Nucleotide, Humans, Linkage (Genetics), Confidence Intervals, Female, Physical Chromosome Mapping, Male, Genome: Human},
date-added = {2010-02-03 11:07:46 +0100},
date-modified = {2010-02-03 11:07:46 +0100},
doi = {10.1101/gr.7156307},
pii = {gr.7156307},
pmid = {17989245},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4933},
rating = {0}
}

@article{Xie:2008p13224,
author = {Benhuai Xie and Wei Pan and Xiaotong Shen},
journal = {Biometrics},
title = {Variable selection in penalized model-based clustering via regularization on grouped parameters},
abstract = {Penalized model-based clustering has been proposed for high-dimensional but small sample-sized data, such as arising from genomic studies; in particular, it can be used for variable selection. A new regularization scheme is proposed to group together multiple parameters of the same variable across clusters, which is shown both analytically and numerically to be more effective than the conventional L(1) penalty for variable selection. In addition, we develop a strategy to combine this grouping scheme with grouping structured variables. Simulation studies and applications to microarray gene expression data for cancer subtype discovery demonstrate the advantage of the new proposal over several existing approaches.},
affiliation = {Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA.},
number = {3},
pages = {921--30},
volume = {64},
year = {2008},
month = {Sep},
language = {eng},
keywords = {Models: Statistical, Humans, Biometry, Leukemia, Cluster Analysis, Artificial Intelligence, Analysis of Variance, Gene Expression Profiling, Genomics},
date-added = {2010-07-01 17:24:23 +0200},
date-modified = {2010-07-01 17:24:31 +0200},
doi = {10.1111/j.1541-0420.2007.00955.x},
pii = {BIOM955},
pmid = {18162109},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Xie-2008-Biometrics_Variable%20selection%20i.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13224},
rating = {5}
}

@article{Munafo:2004p485,
author = {Marcus Munaf{\`o}},
journal = {Nicotine Tob Res},
title = {Replication validity of genetic association studies of smoking behavior: what can meta-analytic techniques offer?},
number = {2},
pages = {381--2},
volume = {6},
year = {2004},
month = {Apr},
language = {eng},
keywords = {Smoking, Tobacco Use Disorder, Polymorphism: Genetic, Humans, Meta-Analysis as Topic, Genetic Predisposition to Disease, Receptors: Dopamine D2, Phenotype, Reproducibility of Results},
date-added = {2010-01-03 12:35:58 +0100},
date-modified = {2010-01-03 12:35:58 +0100},
doi = {10.1080/14622200410001676369},
pii = {33GA05B2BQWA3D8Q},
pmid = {15203812},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Munaf%C3%B2-2004-Nicotine%20Tob%20Res_Replication%20validity.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p485},
rating = {0}
}

@article{Mahon:2009p3376,
author = {Pamela Belmonte Mahon and Jennifer L Payne and Dean F MacKinnon and Francis M Mondimore and Fernando S Goes and Barbara Schweizer and Dubravka Jancic and NIMH Genetics Initiative Bipolar Disorder Consortium and BiGS Consortium and William H Coryell and Peter A Holmans and Jianxin Shi and James A Knowles and William A Scheftner and Myrna M Weissman and Douglas F Levinson and J Raymond DePaulo and Peter P Zandi and James B Potash},
journal = {Am J Psychiatry},
title = {Genome-wide linkage and follow-up association study of postpartum mood symptoms},
abstract = {OBJECTIVE: Family studies have suggested that postpartum mood symptoms might have a partly genetic etiology. The authors used a genome-wide linkage analysis to search for chromosomal regions that harbor genetic variants conferring susceptibility for such symptoms. The authors then fine-mapped their best linkage regions, assessing single nucleotide polymorphisms (SNPs) for genetic association with postpartum symptoms. METHOD: Subjects were ascertained from two studies: the NIMH Genetics Initiative Bipolar Disorder project and the Genetics of Recurrent Early-Onset Depression. Subjects included women with a history of pregnancy, any mood disorder, and information about postpartum symptoms. In the linkage study, 1,210 women met criteria (23% with postpartum symptoms), and 417 microsatellite markers were analyzed in multipoint allele sharing analyses. For the association study, 759 women met criteria (25% with postpartum symptoms), and 16,916 SNPs in the regions of the best linkage peaks were assessed for association with postpartum symptoms. RESULTS: The maximum linkage peak for postpartum symptoms occurred on chromosome 1q21.3-q32.1, with a chromosome-wide significant likelihood ratio Z score (Z(LR)) of 2.93 (permutation p=0.02). This was a significant increase over the baseline Z(LR) of 0.32 observed at this locus among all women with a mood disorder (permutation p=0.004). Suggestive linkage was also found on 9p24.3-p22.3 (Z(LR)=2.91). In the fine-mapping study, the strongest implicated gene was HMCN1 (nominal p=0.00017), containing four estrogen receptor binding sites, although this was not region-wide significant. CONCLUSIONS: This is the first study to examine the genetic etiology of postpartum mood symptoms using genome-wide data. The results suggest that genetic variations on chromosomes 1q21.3-q32.1 and 9p24.3-p22.3 may increase susceptibility to postpartum mood symptoms.},
affiliation = {Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.},
number = {11},
pages = {1229--37},
volume = {166},
year = {2009},
month = {Nov},
language = {eng},
keywords = {Adult, Depression: Postpartum, Humans, Genotype, Middle Aged, Pregnancy, Polymorphism: Single Nucleotide, Chromosome Mapping, Bipolar Disorder, Chromosomes: Human: Pair 1, Follow-Up Studies, Chromosomes: Human: Pair 9, Female, Linkage (Genetics), Genome-Wide Association Study, Pedigree, Depressive Disorder: Major, Models: Genetic, Genetic Predisposition to Disease, Genetic Variation, Microsatellite Repeats},
date-added = {2010-01-15 14:39:52 +0100},
date-modified = {2010-07-29 19:51:28 +0200},
doi = {10.1176/appi.ajp.2009.09030417},
pii = {appi.ajp.2009.09030417},
pmid = {19755578},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3376},
rating = {3}
}

@article{Guyatt:1993p12452,
author = {G H Guyatt and D H Feeny and D L Patrick},
journal = {Ann Intern Med},
title = {Measuring health-related quality of life},
abstract = {Clinicians and policymakers are recognizing the importance of measuring health-related quality of life (HRQL) to inform patient management and policy decisions. Self- or interviewer-administered questionnaires can be used to measure cross-sectional differences in quality of life between patients at a point in time (discriminative instruments) or longitudinal changes in HRQL within patients during a period of time (evaluative instruments). Both discriminative and evaluative instruments must be valid (really measuring what they are supposed to measure) and have a high ratio of signal to noise (reliability and responsiveness, respectively). Reliable discriminative instruments are able to reproducibly differentiate between persons. Responsive evaluative measures are able to detect important changes in HRQL during a period of time, even if those changes are small. Health-related quality of life measures should also be interpretable--that is, clinicians and policymakers must be able to identify differences in scores that correspond to trivial, small, moderate, and large differences. Two basic approaches to quality-of-life measurement are available: generic instruments that provide a summary of HRQL; and specific instruments that focus on problems associated with single disease states, patient groups, or areas of function. Generic instruments include health profiles and instruments that generate health utilities. The approaches are not mutually exclusive. Each approach has its strengths and weaknesses and may be suitable for different circumstances. Investigations in HRQL have led to instruments suitable for detecting minimally important effects in clinical trials, for measuring the health of populations, and for providing information for policy decisions.},
affiliation = {McMaster University, Hamilton, Ontario, Canada.},
number = {8},
pages = {622--9},
volume = {118},
year = {1993},
month = {Apr},
language = {eng},
keywords = {Health Status Indicators, Chronic Disease, Health Services Research, Questionnaires, Quality of Life, Self Assessment (Psychology), Reproducibility of Results, Health Status, Humans, Interviews as Topic, Outcome Assessment (Health Care), Clinical Trials as Topic},
date-added = {2010-06-15 17:32:06 +0200},
date-modified = {2010-07-29 19:14:47 +0200},
pmid = {8452328},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Guyatt-1993-Ann%20Intern%20Med_Measuring%20health-rel.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12452},
rating = {0}
}

@article{Frew:2010p9372,
author = {Paula M Frew and Su-I Hou and Marsha Davis and Kayshin Chan and Takeia Horton and Justin Shuster and Brooke Hixson and Carlos Del Rio},
journal = {Journal of Clinical Epidemiology},
title = {The likelihood of participation in clinical trials can be measured: the Clinical Research Involvement Scales},
abstract = {OBJECTIVE: We developed the Clinical Research Involvement Scales (CRIS) to assess the willingness to participate in a clinical trial. STUDY DESIGN AND SETTING: Diverse populations (N=919) aged 18 years or older from Atlanta, Georgia, were included in comprehensive testing of the 41-item CRIS instrument. The formative phase focused on item content for the new measures (n=54). Questionnaires from potential vaccine trial participants (n=865), collected at multiple time points, resulted in the evaluation of scale reliability and validity (i.e., attitudes, behavioral and normative beliefs, perceived social support for clinical research participation, social norm compliance, perceptions of the clinical research organization, and perceived relevance of the research endeavor). RESULTS: Qualitative testing revealed adequate comprehension and content validity of the initial item set. The subjective norms domain (n=3) initially exhibited poor internal consistency in pilot testing (Cronbach's alpha=0.525); yet, rewording of the items resulted in consistently stable measurement improvement (Cronbach's alpha=0.850). Each of the CRIS subscales demonstrated extremely high reliability, ranging from 0.734 to 0.918. Confirmatory factor analysis verified item-factor relationships and determined construct and convergent validity (root mean square error of approximation=0.068; comparative fit index=0.835). CONCLUSIONS: CRIS is a reliable instrument for measuring community attitudes toward participation in biomedical research studies. Results of this study support the use of these scales to recruit diverse populations to clinical trials.},
affiliation = {Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA; Emory Center for AIDS Research, Atlanta, GA, USA; The Hope Clinic of the Emory Vaccine Center, Decatur, GA, USA; Department of Behavioral Sciences and Health Education and the Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.},
pages = {},
year = {2010},
month = {Mar},
language = {ENG},
date-added = {2010-03-23 18:43:21 +0100},
date-modified = {2010-03-23 18:43:21 +0100},
doi = {10.1016/j.jclinepi.2009.12.002},
pii = {S0895-4356(09)00387-4},
pmid = {20303711},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Frew-2010-Journal%20of%20Clinical%20Epidemiology_The%20likelihood%20of%20pa-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9372},
rating = {0}
}

@article{Bailey:2001,
author = {Michael Bailey},
journal = {Political Analysis},
title = {Ideal point estimation with a small number of votes: A random-effects approach},
number = {3},
pages = {192--210},
volume = {9},
year = {2001},
date-added = {2010-01-10 11:33:25 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bailey-2001-Political%20Analysis_Ideal%20point%20estimati.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2163},
rating = {0}
}

@article{Egli:2006p5579,
author = {Samy Egli and Katharina Schlatter and Roland Streule and Damian L{\"a}ge},
journal = {Psychopathology},
title = {A structure-based expert model of the ICD-10 mental disorders},
abstract = {BACKGROUND: Many authors have highlighted that a classificatory system such as the ICD-10 or the DSM-IV should attempt to integrate categorical as well as dimensional aspects rather than relying only on a categorical distinction. METHODS: In the current study, a method is presented that allows both perspectives to be considered. Based on their clinical experience, 20 therapists were asked to rate a selection of ICD-10 mental disorders in terms of their similarity. The resulting data were processed by nonmetric multidimensional scaling on individual basis as well as mean basis and a cluster analysis. RESULTS: From a categorical point of view, the resulting mean cognitive map and the cluster analytic groups showed a good concordance with the ICD-10 F groups. Additionally, analogies to the critical observations with regard to the classification systems could be observed. From the dimensional point of view, there were two dimensions found (cognition and psychosis) which showed high correlations in the mean map. CONCLUSIONS: The method presented in this study offers an opportunity to account for dimensional as well as categorical aspects of classification by exploring the structure of the ICD-10 mental disorders directly from the point of view of therapists and thus creating the basis for an expert model.},
affiliation = {Institute of Psychology, University of Z{\"u}rich, Z{\"u}rich, Switzerland.},
number = {1},
pages = {1--9},
volume = {39},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Mathematical Computing, Mental Disorders, Expert Systems, Cognition Disorders, Algorithms, International Classification of Diseases, Data Collection, Psychotherapy, Models: Statistical, Reproducibility of Results, Psychiatry, Statistics as Topic, Humans, Cluster Analysis, Psychotic Disorders, Terminology as Topic, Psychometrics},
date-added = {2010-02-12 15:38:34 +0100},
date-modified = {2010-02-12 15:38:34 +0100},
doi = {10.1159/000089657},
pii = {PSP2006039001001},
pmid = {16282713},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5579},
rating = {0}
}

@article{Rijkeboer:2006p13809,
author = {M M Rijkeboer and H van den Bergh},
journal = {Cognitive Therapy Research},
title = {Multiple Group Confirmatory Factor Analysis of the Young Schema-Questionnaire in a Dutch Clinical versus Non-clinical Population},
abstract = {So far, results on the dimensionality of the Young Schema-Questionnaire (YSQ) were based on exploratory factor analysis. In this study, confirmatory techniques were used to investigate the latent structure of the YSQ and its measurement invariance across a Dutch clinical (n = 172) and non-clinical (n = 162) sample. Data support the 16 factor structure as originally hypothesized by Young (Young, J. E. (1994). Cognitive therapy for personality disorders: A schema-focused approach (Rev. ed.). Sarasota, FL: Professional Resource Press), including Social Undesirability, which did not appear as a separate factor in earlier studies. Furthermore, results suggest factorial similarity across both samples. Best fit was found for a model in which inter-factor correlations and factor loadings were specified as invariant across samples while error variances were allowed to vary. An additional finding was that the YSQ can be split into two parallel parts. Parallel tests represent the same underlying constructs, and share identical psychometric properties, but contain different items. Their utilization could be highly profitable for research and clinical practice.},
year = {2006},
date-added = {2010-07-29 12:27:50 +0200},
date-modified = {2010-07-29 12:29:24 +0200},
doi = {10.1007/s10608-006-9051-8},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rijkeboer-2006-Cognitive%20Therapy%20Research_Multiple%20Group%20Confi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13809},
rating = {0}
}

@article{Bauer1999,
author = {E Bauer and A Kohavi},
journal = {Machine Learning},
title = {An empirical comparison of voting classification algorithms: Bagging, Boosting, and Variants},
number = {1-2},
pages = {105--139},
volume = {36},
year = {1999},
date-added = {2010-01-12 14:26:51 +0100},
date-modified = {2010-07-29 19:38:49 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2558},
rating = {0}
}

@article{Blakemore:2006p4826,
author = {Sarah-Jayne Blakemore and Suparna Choudhury},
journal = {J Child Psychol Psychiatry},
title = {Development of the adolescent brain: implications for executive function and social cognition},
abstract = {Adolescence is a time of considerable development at the level of behaviour, cognition and the brain. This article reviews histological and brain imaging studies that have demonstrated specific changes in neural architecture during puberty and adolescence, outlining trajectories of grey and white matter development. The implications of brain development for executive functions and social cognition during puberty and adolescence are discussed. Changes at the level of the brain and cognition may map onto behaviours commonly associated with adolescence. Finally, possible applications for education and social policy are briefly considered.},
affiliation = {Institute of Cognitive Neuroscience, Department of Psychology, University College London, UK. s.blakemore@ucl.ac.uk},
number = {3-4},
pages = {296--312},
volume = {47},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Magnetic Resonance Imaging, Social Perception, Brain, Humans, Adolescent, Cognition},
date-added = {2010-02-01 20:21:57 +0100},
date-modified = {2010-07-29 19:32:47 +0200},
doi = {10.1111/j.1469-7610.2006.01611.x},
pii = {JCPP1611},
pmid = {16492261},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4826},
rating = {0}
}

@article{Liu:2010p5899,
author = {H Liu and T Wu},
title = {Estimating the Area under a Receiver Operating Characteristic (ROC) Curve For Repeated Measures Design},
abstract = {The receiver operating characteristic (ROC) curve is widely used for diagnosing as well as for judging the discrimination ability of different statistical models. Although theories about ROC curves have been established and computation methods and computer software are available for cross-sectional design, limited research for estimating ROC curves and their summary statistics has been done for repeated measure designs, which are useful in many applications, such as biological, medical and health services research. Furthermore, there is no published statistical software available that can generate ROC curves and calculate summary statistics of the area under a ROC curve for data from a repeated measures design. Using generalized linear mixed model (GLMM), we estimate the predicted probabilities of the positivity of a disease or condition, and the estimated probability is then used as a bio-marker for constructing the ROC curve and computing the area under the curve. The area under a ROC curve is calculated using the Wilcoxon non-parametric approach by comparing the predicted probability of all discordant pairs of observations. The ROC curve is constructed by plotting a series of pairs of true positive rate (sensitivity) and false positive rate (1- specificity) calculated from varying cuts of positivity escalated by increments of 0.005 in predicted probability. The computation software is written in SAS/IML/MACRO v8 and can be executed in any computer that has a working SAS v8 system with SAS/IML/MACRO.},
date-added = {2010-02-17 21:31:51 +0100},
date-modified = {2010-02-17 21:32:24 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Liu--_Estimating%20the%20Area.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5899},
rating = {0}
}

@article{Liu:2010p2663,
author = {H Liu and R D Hays},
journal = {1999},
title = {Measurement of Interrater Agreement A SAS/IML Macro Kappa Procedure for Handling Incomplete Data},
abstract = {Reliability refers to the extent to which the same score is obtained on multiple administrations. Interrater reliability is evaluated by comparing scores assigned to the same targets by two or more raters. Kappa is perhaps the most commonly used index of interrater agreement. Kappa is scaled to be 0 when the amount of agreement is what would be expected to be observed by chance and 1 when there is perfect agreement. Kappa can be obtained from SAS PROC FREQ, but this procedure can only handle complete data (i.e., each rater uses every possible choice on the response scale at least once). For incomplete data, one will either be unable to get kappa (if non-square table) or one will get a wrong kappa (if irregular square table) through SAS. This paper introduces a SAS macro procedure that calculates the correct kappa for either complete or incomplete data, and allows the user to specify any of three different weighting schemes. The SAS products	included	are	Base	SAS, SAS/ST A T,	SAS/IML	and	SAS MACRO. This procedure can be run on any computer platform with a working SAS system by even an entry-level analyst.},
date-added = {2010-01-12 22:55:26 +0100},
date-modified = {2010-01-12 22:57:15 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Liu--1999_Measurement%20of%20Inter.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2663},
rating = {0}
}

@article{Barry:2008p9099,
author = {Robin A Barry and Grazyna Kochanska and Robert A Philibert},
journal = {J Child Psychol Psychiatry},
title = {G x E interaction in the organization of attachment: mothers' responsiveness as a moderator of children's genotypes},
abstract = {BACKGROUND: Scholars acknowledge that both biologically-founded child temperament and environmental factors are influential in determining the quality of infant-mother attachment. We present evidence for gene by environment (G x E) interaction in the organization of attachment. METHODS: Participants were 88 typically developing infants and their mothers. Molecular genetic measures of the infants focused on the polymorphism in the serotonin transporter gene (5-HTTLPR, ss/sl vs. ll genotype). Mothers' responsiveness to their infants at 7 months was observed in lengthy naturalistic interactions, and was conceptualized as the environmental influence. RESULTS: For infants with a short allele (ss/sl ), variation in mothers' responsiveness was significantly associated with attachment security, assessed at 15 months in the Strange Situation. For those infants, low responsiveness predicted particularly high risk for insecure attachment, and high responsiveness offset that risk. For infants homozygous for the long allele (ll ), there was no association between responsiveness and attachment organization. CONCLUSIONS: The findings show that the quality of early care serves to amplify or offset the risk conferred by genotype.},
affiliation = {Department of Psychology, University of Iowa, Iowa City, Iowa 52242, USA. robin-barry@uiowa.edu},
number = {12},
pages = {1313--20},
volume = {49},
year = {2008},
month = {Dec},
language = {eng},
keywords = {Longitudinal Studies, Serotonin Plasma Membrane Transport Proteins, Genetic Predisposition to Disease, Humans, Mother-Child Relations, Social Environment, Temperament, Male, Alleles, Mothers, Polymorphism: Genetic, Risk Factors, Child: Preschool, Predictive Value of Tests, Object Attachment, Affective Symptoms, Infant, Female},
date-added = {2010-03-22 13:25:32 +0100},
date-modified = {2010-07-29 19:32:47 +0200},
doi = {10.1111/j.1469-7610.2008.01935.x},
pii = {JCPP1935},
pmid = {19120710},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Barry-2008-J%20Child%20Psychol%20Psychiatry_G%20x%20E%20interaction%20in.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9099},
rating = {0}
}

@article{Romera:2010p7796,
author = {I Romera and V Perez and J M Mench{\'o}n and H Delgado-Cohen and P Polavieja and I Gilaberte},
journal = {Eur Psychiatry},
title = {Social and occupational functioning impairment in patients in partial versus complete remission of a major depressive disorder episode. A six-month prospective epidemiological study},
abstract = {PURPOSE: To evaluate social and occupational functioning in patients in partial remission (PR) compared with patients in complete remission (CR) of a major depressive disorder (MDD) episode. SUBJECTS AND METHODS: This is a six-month prospective study. PR was defined as a score more than 7 and less or equal to 15 in the Hamilton Depression Rating Scale, and CR as less or equal to 7. All patients had been on acute antidepressant treatment during the previous three months and no longer met criteria for MDD. Functioning was assessed by the Social and Occupational Functioning Assessment Scale (SOFAS). RESULTS: Mean (S.D.) patient age was 50.5 (14.5) years (N=292) and 77% were female. At baseline, partial remitters showed greater impairment in social and occupational functioning than complete remitters (62.8 [12.6] versus 80.4 [10.5], respectively; P<.0001). After six months, only 47% PR versus 77% CR reached normal functioning, and SOFAS ratings for PR were below normal range (76.2 [12.3] PR versus 84.6 [9.4] CR; P<.0001). PR reported three times more days absent from work due to sickness than CR (63 days versus 20 days; P<.001). CONCLUSION: We conclude that PR of an MDD episode is associated with significant functional impairment that persists even after nine months of antidepressant treatment. Our results underline the importance of treating the patient until achieving full remission.},
affiliation = {Clinical Research Department, Lilly, SA, Avenida de la Industria, 30, Alcobendas, 28108 Madrid, Spain. romera_irene@lilly.com},
number = {1},
pages = {58--65},
volume = {25},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-03-17 21:00:23 +0100},
date-modified = {2010-03-17 21:00:23 +0100},
doi = {10.1016/j.eurpsy.2009.02.007},
pii = {S0924-9338(09)00094-7},
pmid = {19553092},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Romera-2010-Eur%20Psychiatry_Social%20and%20occupatio.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7796},
rating = {0}
}

@article{Knopik:2004p1346,
author = {Valerie S Knopik and Andrew C Heath and Pamela A F Madden and Kathleen K Bucholz and Wendy S Slutske and Elliot C Nelson and Dixie Statham and John B Whitfield and Nicholas G Martin},
journal = {Psychol Med},
title = {Genetic effects on alcohol dependence risk: re-evaluating the importance of psychiatric and other heritable risk factors},
abstract = {BACKGROUND: Genetic influences have been shown to play a major role in determining the risk of alcohol dependence (AD) in both women and men; however, little attention has been directed to identifying the major sources of genetic variation in AD risk. METHOD: Diagnostic telephone interview data from young adult Australian twin pairs born between 1964 and 1971 were analyzed. Cox regression models were fitted to interview data from a total of 2708 complete twin pairs (690 MZ female, 485 MZ male, 500 DZ female, 384 DZ male, and 649 DZ female/male pairs). Structural equation models were fitted to determine the extent of residual genetic and environmental influences on AD risk while controlling for effects of sociodemographic and psychiatric predictors on risk. RESULTS: Risk of AD was increased in males, in Roman Catholics, in those reporting a history of major depression, social anxiety problems, and conduct disorder, or (in females only) a history of suicide attempt and childhood sexual abuse;

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repo_name: sergiud/bibtex-spirit

gha_license_id: MIT