text:
-03-10 20:23:32 +0100},
date-modified = {2010-04-25 21:26:12 +0200},
doi = {10.1002/sim.1713},
pmid = {14716726},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Crane-2004-Stat%20Med_Test%20bias%20in%20a%20cogni.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7342},
rating = {4}
}

@article{Huang:2006p3050,
author = {Frederick Y Huang and Henry Chung and Kurt Kroenke and Kevin L Delucchi and Robert L Spitzer},
journal = {J Gen Intern Med},
title = {Using the Patient Health Questionnaire-9 to measure depression among racially and ethnically diverse primary care patients},
abstract = {OBJECTIVE: The Patient Health Questionnaire depression scale (PHQ-9) is a well-validated, Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV) criterion-based measure for diagnosing depression, assessing severity and monitoring treatment response. The performance of most depression scales including the PHQ-9, however, has not been rigorously evaluated in different racial/ethnic populations. Therefore, we compared the factor structure of the PHQ-9 between different racial/ethnic groups as well as the rates of endorsement and differential item functioning (DIF) of the 9 items of the PHQ-9. The presence of DIF would indicate that responses to an individual item differ significantly between groups, controlling for the level of depression. MEASUREMENTS: A combined dataset from 2 separate studies of 5,053 primary care patients including non-Hispanic white (n=2,520), African American (n=598), Chinese American (n=941), and Latino (n=974) patients was used for our analysis. Exploratory principal components factor analysis was used to derive the factor structure of the PHQ-9 in each of the 4 racial/ethnic groups. A generalized Mantel-Haenszel statistic was used to test for DIF. RESULTS: One main factor that included all PHQ-9 items was found in each racial/ethnic group with alpha coefficients ranging from 0.79 to 0.89. Although endorsement rates of individual items were generally similar among the 4 groups, evidence of DIF was found for some items. CONCLUSIONS: Our analyses indicate that in African American, Chinese American, Latino, and non-Hispanic white patient groups the PHQ-9 measures a common concept of depression and can be effective for the detection and monitoring of depression in these diverse populations.},
affiliation = {Department of Psychiatry, University of California, San Francisco, CA, USA. freddy@post.harvard.edu},
number = {6},
pages = {547--52},
volume = {21},
year = {2006},
month = {Jun},
language = {eng},
keywords = {Depressive Disorder, Middle Aged, Continental Population Groups, Questionnaires, Mental Health, Adult, Male, Ethnic Groups, Female, Humans, Depression},
date-added = {2010-01-14 11:25:33 +0100},
date-modified = {2010-01-14 11:25:33 +0100},
doi = {10.1111/j.1525-1497.2006.00409.x},
pii = {JGI409},
pmid = {16808734},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Huang-2006-J%20Gen%20Intern%20Med_Using%20the%20Patient%20He.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3050},
rating = {0}
}

@article{Beauchaine:2009p9083,
author = {Theodore P Beauchaine and Daniel N Klein and Sheila E Crowell and Christina Derbidge and Lisa Gatzke-Kopp},
journal = {Dev Psychopathol},
title = {Multifinality in the development of personality disorders: a Biology x Sex x Environment interaction model of antisocial and borderline traits},
abstract = {Although antisocial personality disorder (ASPD) is more common among males and borderline PD (BPD) is more common among females, some authors have suggested that the two disorders reflect multifinal outcomes of a single etiology. This assertion is based on several overlapping symptoms and features, including trait impulsivity, emotional lability, high rates of depression and suicide, and a high likelihood of childhood abuse and/or neglect. Furthermore, rates of ASPD are elevated in the first degree relatives of those with BPD, and concurrent comorbidity rates for the two disorders are high. In this article, we present a common model of antisocial and borderline personality development. We begin by reviewing issues and problems with diagnosing and studying PDs in children and adolescents. Next, we discuss dopaminergic and serotonergic mechanisms of trait impulsivity as predisposing vulnerabilities to ASPD and BPD. Finally, we extend shared risk models for ASPD and BPD by specifying genetic loci that may confer differential vulnerability to impulsive aggression and mood dysregulation among males and impulsive self-injury and mood dysregulation among females. Although the precise mechanisms of these sex-moderated genetic vulnerabilities remain poorly understood, they appear to interact with environmental risk factors including adverse rearing environments to potentiate the development of ASPD and BPD.},
affiliation = {Department of Psychology, University of Washington, Seattle, WA 98195-1525, USA. tbeaucha@u.washington.edu},
number = {3},
pages = {735--70},
volume = {21},
year = {2009},
month = {Jul},
language = {eng},
keywords = {Affect, Antisocial Personality Disorder, Incidence, Female, Self-Injurious Behavior, Emotions, Sex Characteristics, Humans, Borderline Personality Disorder, Behavior, Male, Impulse Control Disorders, Risk Factors, Models: Psychological, Stereotyped Behavior, Prisons, Environment},
date-added = {2010-03-22 13:21:48 +0100},
date-modified = {2010-03-22 13:21:49 +0100},
doi = {10.1017/S0954579409000418},
pii = {S0954579409000418},
pmid = {19583882},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Beauchaine-2009-Dev%20Psychopathol_Multifinality%20in%20the.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9083},
rating = {0}
}

@article{Atkinson:2006p11233,
author = {Mark J Atkinson and Jan Lohs and Ilka Kuhagen and Julie Kaufman and Shamsu Bhaidani},
journal = {Health Qual Life Outcomes},
title = {A promising method for identifying cross-cultural differences in patient perspective: the use of Internet-based focus groups for content validation of new patient reported outcome assessments},
abstract = {OBJECTIVES: This proof of concept (POC) study was designed to evaluate the use of an Internet-based bulletin board technology to aid parallel cross-cultural development of thematic content for a new set of patient-reported outcome measures (PROs). METHODS: The POC study, conducted in Germany and the United States, utilized Internet Focus Groups (IFGs) to assure the validity of new PRO items across the two cultures--all items were designed to assess the impact of excess facial oil on individuals' lives. The on-line IFG activities were modeled after traditional face-to-face focus groups and organized by a common 'Topic' Guide designed with input from thought leaders in dermatology and health outcomes research. The two sets of IFGs were professionally moderated in the native language of each country. IFG moderators coded the thematic content of transcripts, and a frequency analysis of code endorsement was used to identify areas of content similarity and difference between the two countries. Based on this information, draft PRO items were designed and a majority (80%) of the original participants returned to rate the relative importance of the newly designed questions. FINDINGS: The use of parallel cross-cultural content analysis of IFG transcripts permitted identification of the major content themes in each country as well as exploration of the possible reasons for any observed differences between the countries. Results from coded frequency counts and transcript reviews informed the design and wording of the test questions for the future PRO instrument(s). Subsequent ratings of item importance also deepened our understanding of potential areas of cross-cultural difference, differences that would be explored over the course of future validation studies involving these PROs. CONCLUSION: The use of IFGs for cross-cultural content development received positive reviews from participants and was found to be both cost and time effective. The novel thematic coding methodology provided an empirical platform on which to develop culturally sensitive questionnaire content using the natural language of participants. Overall, the IFG responses and thematic analyses provided a thorough evaluation of similarities and differences in cross-cultural themes, which in turn acted as a sound base for the development of new PRO questionnaires.},
affiliation = {Worldwide Health Outcomes Research, La Jolla Laboratories, Pfizer Inc,, San Diego, CA 92121, USA. mjatkinson@ucsd.edu},
pages = {64},
volume = {4},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Dermatology, Humans, Scalp, Face, Cross-Cultural Comparison, Skin Diseases, Focus Groups, Germany, Internet, Attitude to Health, Psychometrics, Sebum, Outcome Assessment (Health Care), United States},
date-added = {2010-04-25 21:31:40 +0200},
date-modified = {2010-04-25 21:31:45 +0200},
doi = {10.1186/1477-7525-4-64},
pii = {1477-7525-4-64},
pmid = {16995935},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Atkinson-2006-Health%20and%20Quality%20of%20Life%20Outcomes_A%20promising%20method%20f.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11233},
rating = {4}
}

@article{Piek:2004p12970,
author = {Jan P Piek and Murray J Dyck and Ally Nieman and Mike Anderson and David Hay and Leigh M Smith and Mairead McCoy and Joachim Hallmayer},
journal = {Arch Clin Neuropsychol},
title = {The relationship between motor coordination, executive functioning and attention in school aged children},
abstract = {Given the high level of comorbidity of attention deficit hyperactivity disorder (ADHD) and developmental coordination disorder (DCD), deficits in executive function (EF), shown to be present in children with ADHD, may also be implicated in the motor coordination deficits of children with DCD. The aim of this study was to explore the relationship between EF and motor ability. A sample of 238 children, 121 girls and 117 boys, aged between 6 and 15 years was recruited for this project. Motor ability was assessed using the McCarron Assessment of Neuromuscular Development (MAND), level of inattention using the Child Behavior Checklist (CBCL), and Verbal IQ (VIQ) was estimated using subtests of the WISC-III. A reaction time task and three EF tasks measuring response inhibition, working memory and the ability to plan and respond to goal-directed tasks were administered. It was found that motor ability significantly accounted for variance in tasks measuring speed of performance, whereas inattention appeared to influence performance variability. Despite past evidence linking poor motor ability with inattention, there was little overlap in the processes that are affected in children with motor coordination or attention problems.},
affiliation = {School of Psychology, Curtin University of Technology, GPO Box U1987, Perth 6845, Australia. j.piek@curtin.edu.au},
number = {8},
pages = {1063--76},
volume = {19},
year = {2004},
month = {Dec},
language = {eng},
keywords = {Reaction Time, Male, Attention Deficit Disorder with Hyperactivity, Motor Skills Disorders, Severity of Illness Index, Students, Neuropsychological Tests, Female, Child, Humans, Choice Behavior, Prevalence, Schools, Adolescent},
date-added = {2010-06-25 22:27:20 +0200},
date-modified = {2010-06-25 22:27:21 +0200},
doi = {10.1016/j.acn.2003.12.007},
pii = {S0887617704000083},
pmid = {15533697},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Piek-2004-Arch%20Clin%20Neuropsychol_The%20relationship%20bet.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12970},
rating = {0}
}

@article{Nichols:2002p14037,
author = {Thomas E Nichols and Andrew P Holmes},
journal = {Hum Brain Mapp},
title = {Nonparametric permutation tests for functional neuroimaging: a primer with examples},
abstract = {Requiring only minimal assumptions for validity, nonparametric permutation testing provides a flexible and intuitive methodology for the statistical analysis of data from functional neuroimaging experiments, at some computational expense. Introduced into the functional neuroimaging literature by Holmes et al. ([1996]: J Cereb Blood Flow Metab 16:7-22), the permutation approach readily accounts for the multiple comparisons problem implicit in the standard voxel-by-voxel hypothesis testing framework. When the appropriate assumptions hold, the nonparametric permutation approach gives results similar to those obtained from a comparable Statistical Parametric Mapping approach using a general linear model with multiple comparisons corrections derived from random field theory. For analyses with low degrees of freedom, such as single subject PET/SPECT experiments or multi-subject PET/SPECT or fMRI designs assessed for population effects, the nonparametric approach employing a locally pooled (smoothed) variance estimate can outperform the comparable Statistical Parametric Mapping approach. Thus, these nonparametric techniques can be used to verify the validity of less computationally expensive parametric approaches. Although the theory and relative advantages of permutation approaches have been discussed by various authors, there has been no accessible explication of the method, and no freely distributed software implementing it. Consequently, there have been few practical applications of the technique. This article, and the accompanying MATLAB software, attempts to address these issues. The standard nonparametric randomization and permutation testing ideas are developed at an accessible level, using practical examples from functional neuroimaging, and the extensions for multiple comparisons described. Three worked examples from PET and fMRI are presented, with discussion, and comparisons with standard parametric approaches made where appropriate. Practical considerations are given throughout, and relevant statistical concepts are expounded in appendices.},
affiliation = {Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.},
number = {1},
pages = {1--25},
volume = {15},
year = {2002},
month = {Jan},
language = {eng},
keywords = {Data Interpretation: Statistical, Image Processing: Computer-Assisted, Brain, Tomography: Emission-Computed, Humans, Statistical Distributions, Magnetic Resonance Imaging, Brain Mapping, Signal Processing: Computer-Assisted},
date-added = {2010-08-09 10:08:39 +0200},
date-modified = {2010-08-09 10:08:39 +0200},
pii = {10.1002/hbm.1058},
pmid = {11747097},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Nichols-2002-Hum%20Brain%20Mapp_Nonparametric%20permut.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14037},
rating = {0}
}

@article{Douglas:2001p2688,
author = {J Douglas and A Cohen},
journal = {Applied Psychological Measurement},
title = {Nonparametric Item Response Function Estimation for Assessing Parametric Model Fit},
abstract = {Methods are developed that investigate the fit of parametric item response models by comparing them to models fitted under nonparametric assumptions. The approach is primarily graphical, but is made inferential through resampling from an estimated parametric model. The identifiability and estimation consistency of item response theory models are discussed and shown to be vital to the interpretation of differences between two fitted item response theory models. Simulation studies and real-data examples illustrate these techniques.},
number = {3},
pages = {234--243},
volume = {25},
year = {2001},
date-added = {2010-01-13 10:08:34 +0100},
date-modified = {2010-07-29 19:16:53 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Douglas-2001-Applied%20Psychological%20Measurement_Nonparametric%20Item%20R.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2688},
rating = {0}
}

@article{Fan:2008p2327,
author = {Y Fan and D S Leslie and M P Wand},
journal = {Electronic Journal of Statistics},
title = {Generalised linear mixed model analysis via sequential Monte Carlo sampling},
abstract = {We present a sequential Monte Carlo sampler algorithm for the Bayesian analysis of generalised linear mixed models (GLMMs). These models support a variety of interesting regression-type analyses, but per- forming inference is often extremely difficult, even when using the Bayesian approach combined with Markov chain Monte Carlo (MCMC). The Sequen- tial Monte Carlo sampler (SMC) is a new and general method for producing samples from posterior distributions. In this article we demonstrate use of the SMC method for performing inference for GLMMs. We demonstrate the effectiveness of the method on both simulated and real data, and find that sequential Monte Carlo is a competitive alternative to the available MCMC techniques.},
pages = {916--938},
volume = {2},
year = {2008},
date-added = {2010-01-10 12:54:04 +0100},
date-modified = {2010-01-10 12:55:47 +0100},
doi = {10.1214/07-EJS158},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fan-2008-Electronic%20Journal%20of%20Statistics_Generalised%20linear%20m.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2327},
rating = {0}
}

@article{Pals:2009p6408,
author = {Sherri L Pals and Brenda L Beaty and Samuel F Posner and Sheana S Bull},
journal = {Health Educ Behav},
title = {Estimates of intraclass correlation for variables related to behavioral HIV/STD prevention in a predominantly African American and Hispanic sample of young women},
abstract = {Studies designed to evaluate HIV and STD prevention interventions often involve random assignment of groups such as neighborhoods or communities to study conditions (e.g., to intervention or control). Investigators who design group-randomized trials (GRTs) must take the expected intraclass correlation coefficient (ICC) into account in sample size estimation to have adequate power; however, few published ICC estimates exist for outcome variables related to HIV and STD prevention. The Prevention Options for Women Equal Rights (POWER) study was a GRT designed to evaluate a campaign to increase awareness and use of condoms among young African American and Hispanic women. The authors used precampaign and postcampaign data from the POWER study to estimate ICCs (unadjusted and adjusted for covariates) for a variety of sexual behavior and other variables. To illustrate the impact of ICCs on power, the authors present sample-size calculations and demonstrate how ICCs of differing magnitude will affect estimates of required sample size.},
affiliation = {Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. sfv3@cdc.gov},
number = {1},
pages = {182--94},
volume = {36},
year = {2009},
month = {Feb},
language = {eng},
keywords = {Adolescent, Condoms, Adult, Risk-Taking, Humans, Young Adult, African Americans, Risk Reduction Behavior, Educational Status, Sexually Transmitted Diseases, Social Class, Hispanic Americans, HIV Infections, Female, Health Knowledge: Attitudes: Practice, Cross-Sectional Studies, Regression Analysis, Sexual Behavior},
date-added = {2010-02-23 08:25:38 +0100},
date-modified = {2010-02-23 08:25:38 +0100},
doi = {10.1177/1090198108327731},
pii = {36/1/182},
pmid = {19188372},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6408},
rating = {0}
}

@article{Vanderweele:2010p3066,
author = {T J Vanderweele},
journal = {Statistical Applications in Genetics and Molecular Biology},
title = {Epistatic Interactions},
abstract = {The term ``epistasis'' is sometimes used to describe some form of statistical interaction be- tween genetic factors and is alternatively sometimes used to describe instances in which the effect of a particular genetic variant is masked by a variant at another locus. In general statistical tests for interaction are of limited use in detecting ''epistasis'' in the sense of masking. It is, however, shown that there are relations between empirical data patterns and epistasis that have not been previously noted. These relations can sometimes be exploited to empirically test for ''epistatic interactions'' in the sense of the masking of the effect of a particular genetic variant by a variant at another locus.},
number = {1},
volume = {9},
year = {2010},
date-added = {2010-01-14 11:31:53 +0100},
date-modified = {2010-01-14 11:32:47 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Vanderweele-2010-Statistical%20Applications%20in%20Genetics%20and%20Molecular%20Biology_Epistatic%20Interactio.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3066},
rating = {0}
}

@article{Sun:2009p1512,
author = {Ning Sun and Hongyu Zhao},
journal = {Stat Methods Med Res},
title = {Reconstructing transcriptional regulatory networks through genomics data},
abstract = {One central problem in biology is to understand how gene expression is regulated under different conditions. Microarray gene expression data and other high throughput data have made it possible to dissect transcriptional regulatory networks at the genomics level. Owing to the very large number of genes that need to be studied, the relatively small number of data sets available, the noise in the data and the different natures of the distinct data types, network inference presents great challenges. In this article, we review statistical and computational methods that have been developed in the last decade in response to genomics data for inferring transcriptional regulatory networks.},
affiliation = {Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA. ning.sun@yale.edu},
number = {6},
pages = {595--617},
volume = {18},
year = {2009},
month = {Dec},
language = {eng},
date-added = {2010-01-07 12:27:07 +0100},
date-modified = {2010-01-07 12:27:07 +0100},
doi = {10.1177/0962280209351890},
pii = {18/6/595},
pmid = {20048387},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sun-2009-Stat%20Methods%20Med%20Res_Reconstructing%20trans.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1512},
rating = {0}
}

@article{vandenOord:2008p3801,
author = {Edwin J C G van den Oord and Po-Hsiu Kuo and Annette M Hartmann and B Todd Webb and Hans-J{\"u}rgen M{\"o}ller and John M Hettema and Ina Giegling and J{\'o}zsef Buksz{\'a}r and Dan Rujescu},
journal = {Arch Gen Psychiatry},
title = {Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism},
abstract = {CONTEXT: Neuroticism is a trait that reflects a tendency toward negative mood states. It has long been linked to internalizing psychiatric conditions, such as anxiety and depression, and it accounts for much of the substantial comorbidity seen between these disorders. OBJECTIVE: To identify common genetic variants that affect neuroticism to better understand (the comorbidity between) a broad range of psychiatric disorders and to develop effective treatments. DESIGN, SETTING, AND PARTICIPANTS: More than 420,000 genetic markers were tested for their association with neuroticism in a genomewide association study (GWAS). The GWAS sample consisted of 1227 healthy individuals ascertained from a US national sampling frame and available from the National Institute of Mental Health genetics repository. The most promising markers were subsequently tested in a German replication sample comprising 1880 healthy individuals. MAIN OUTCOME MEASURES: A strict definition of replication (same marker, same direction of effects, and same measure) combined with a threshold we proposed previously for declaring significance in genetic studies that ensures a mean probability of producing false-positive findings of less than 10%. RESULTS: The most promising results in the GWAS and replication samples were single-nucleotide polymorphisms (SNPs) in the gene MAMDC1. These SNPs all tagged the same 2 haplotypes and had P values of 10(-5) to 10(-6) in the GWAS sample and of .006 to .02 in the replication sample. Furthermore, the replication involved the same SNPs and the same direction of effects. In a combined analysis of all data, several SNPs were significant according to the threshold that allows for 10% false-positive findings. CONCLUSIONS: The small effect sizes may limit the prognostic, diagnostic, and therapeutic use of SNP markers such as those in MAMDC1. However, the present study demonstrates the potential of a GWAS to discover potentially important pathogenic pathways for which clinically more powerful (bio)markers may eventually be developed.},
affiliation = {Center for Biomarker Research and Personalized Medicine, Medical College of Virginia, Virginia Commonwealth University, PO Box 980533, Richmond, VA 23298-0533, USA. ejvandenoord@vcu.edu},
number = {9},
pages = {1062--71},
volume = {65},
year = {2008},
month = {Sep},
language = {eng},
keywords = {Gene Expression, Aged, Adult, Glycosylphosphatidylinositols, Adolescent, Middle Aged, Humans, Genetic Markers, DNA Replication, Neurotic Disorders, Male, Genotype, Genome, Female, Polymorphism: Single Nucleotide},
date-added = {2010-01-16 21:00:53 +0100},
date-modified = {2010-01-16 21:00:55 +0100},
doi = {10.1001/archpsyc.65.9.1062},
pii = {65/9/1062},
pmid = {18762592},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3801},
rating = {3}
}

@article{Cook:2009p7291,
author = {Benjamin L{\^e} Cook and Willard G Manning},
journal = {Health Serv Res},
title = {Measuring racial/ethnic disparities across the distribution of health care expenditures},
abstract = {OBJECTIVE: To assess whether black-white and Hispanic-white disparities increase or abate in the upper quantiles of total health care expenditure, conditional on covariates. DATA SOURCE: Nationally representative adult population of non-Hispanic whites, African Americans, and Hispanics from the 2001-2005 Medical Expenditure Panel Surveys. STUDY DESIGN: We examine unadjusted racial/ethnic differences across the distribution of expenditures. We apply quantile regression to measure disparities at the median, 75th, 90th, and 95th quantiles, testing for differences over the distribution of health care expenditures and across income and education categories. We test the sensitivity of the results to comparisons based only on health status and estimate a two-part model to ensure that results are not driven by an extremely skewed distribution of expenditures with a large zero mass. PRINCIPAL FINDINGS: Black-white and Hispanic-white disparities diminish in the upper quantiles of expenditure, but expenditures for blacks and Hispanics remain significantly lower than for whites throughout the distribution. For most education and income categories, disparities exist at the median and decline, but remain significant even with increased education and income. CONCLUSIONS: Blacks and Hispanics receive significantly disparate care at high expenditure levels, suggesting prioritization of improved access to quality care among minorities with critical health issues.},
affiliation = {Cambridge Health Alliance/Harvard Medical School, Center for Multicultural Mental Health Research, Somerville, MA 02143, USA. bcook@charesearch.org},
number = {5 Pt 1},
pages = {1603--21},
volume = {44},
year = {2009},
month = {Oct},
language = {eng},
keywords = {Health Expenditures, Healthcare Disparities, Humans, Health Services Research, Ethnic Groups, United States, Health Status, Socioeconomic Factors, Continental Population Groups},
date-added = {2010-03-10 20:18:46 +0100},
date-modified = {2010-03-10 20:18:46 +0100},
doi = {10.1111/j.1475-6773.2009.01004.x},
pii = {HESR1004},
pmid = {19656228},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7291},
rating = {0}
}

@article{Diaz:2005p3624,
author = {M M Diaz and V G Ones},
journal = {Revista Colombiana de Estad ́ıstica},
title = {Estimating multilevel models for categorical data via generalized least squares},
abstract = {Montero et al. (2002) proposed a strategy to formulate multilevel models related to a contingency table sample. This methodology is based on the application of the general linear model to hierarchical categorical data. In this paper we applied the method to a multilevel logistic regression model using simulated data. We find that the estimates of the random parameters are inadmissible in some circumstances; large bias and negative estimates of the variance are expected for unbalanced data sets. In order to correct the estimates we propose to use a numerical technique based on the Trun- cated Singular Value Decomposition (TSVD) in the solution of the problem of generalized least squares associated to the estimation of the random pa- rameters. Finally a simulation study is presented to shows the effectiveness of this technique for reducing the bias of the estimates.},
number = {1},
pages = {63--76},
volume = {28},
year = {2005},
date-added = {2010-01-16 18:43:38 +0100},
date-modified = {2010-07-29 19:49:11 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Diaz-2005-Revista%20Colombiana%20de%20Estad%20%CC%81%C4%B1stica_Estimating%20multileve.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3624},
rating = {0}
}

@article{Anonymous:2005p3283,
journal = {The Economist},
title = {The Economist Intelligence Unit's quality-of-life index},
year = {2005},
date-added = {2010-01-14 21:15:07 +0100},
date-modified = {2010-01-14 21:15:32 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/2005-The%20Economist_The%20Economist%20Intell.PDF},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3283},
read = {Yes},
rating = {0}
}

@article{Yu:2007,
author = {C H Yu and S O Popp and S DiGangi and A Jannasch-Pennell},
journal = {Practical Assessment Research {\&} Evaluation},
title = {Assessing unidimensionality: A comparison of Rasch modeling, Parallel analysis, and TETRAD},
abstract = {The evaluation of assessment dimensionality is a necessary stage in the gathering of evidence to support the validity of interpretations based on a total score, particularly when assessment development and analysis are conducted within an item response theory (IRT) framework. In this study, we employ polytomous item responses to compare two methods that have received increased attention in recent years (Rasch model and Parallel analysis) with a method for evaluating assessment structure that is less well-known in the educational measurement community (TETRAD). The three methods were all found to be reasonably effective. Parallel Analysis successfully identified the correct number of factors and while the Rasch approach did not show the item misfit that would indicate deviation from clear unidimensionality, the pattern of residuals did seem to indicate the presence of correlated, yet distinct, factors. TETRAD successfully confirmed one dimension in the single-construct data set and was able to confirm two dimensions in the combined data set, yet excluded one item from each cluster, for no obvious reasons. The outcomes of all three approaches substantiate the conviction that the assessment of dimensionality requires a good deal of judgment.},
number = {14},
volume = {12},
year = {2007},
date-added = {2010-01-03 19:38:21 +0100},
date-modified = {2010-07-29 19:44:42 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1156},
read = {Yes},
rating = {0}
}

@article{Osborn:2010p13383,
author = {Chandra Y Osborn and Terry C Davis and Stacy Cooper Bailey and Michael S Wolf},
journal = {AIDS Behav},
title = {Health literacy in the context of HIV treatment: introducing the Brief Estimate of Health Knowledge and Action (BEHKA)-HIV version},
abstract = {A brief, 8-item assessment of HIV treatment knowledge and action was developed and evaluated. Patients with HIV were interviewed in 2001 at infectious disease clinics in Shreveport, LA and Chicago, IL. Analyses on demographics, self-reported medication adherence, and responses to the Rapid Estimate of Adult Literacy in Medicine (REALM) and new, Brief Estimate of Health Knowledge and Action-HIV version (BEHKA-HIV) were performed in 2007. The BEHKA-HIV demonstrated high internal consistency, and construct validity. Lower scores on the BEHKA-HIV were independently associated with poorer rates of HIV medication adherence, scores 4-5 out of 8, AOR 2.6 (95% CI 1.9-3.6), and scores 0-3, AOR 11.4 (95% CI 8.2-15.9), as were the lowest scores on the REALM, AOR 3.3 (95% CI 1.3-8.7). The BEHKA-HIV is a psychometrically sound tool for assessing health knowledge and action regarding HIV treatment, and predicting non-adherence to HIV medications.},
affiliation = {Division of General Internal Medicine and Public Health, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN 37232-8300, USA. chandra.osborn@vanderbilt.edu},
number = {1},
pages = {181--8},
volume = {14},
year = {2010},
month = {Feb},
language = {eng},
keywords = {Adult, Humans, Awareness, Health Behavior, Prevalence, Patient Compliance, Antiviral Agents, Male, CD4 Lymphocyte Count, HIV Infections, Questionnaires, Attitude to Health, Health Literacy, Female},
date-added = {2010-07-01 19:24:03 +0200},
date-modified = {2010-07-01 19:24:03 +0200},
doi = {10.1007/s10461-008-9484-z},
pmid = {19023653},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Osborn-2010-AIDS%20Behav_Health%20literacy%20in%20t.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13383},
rating = {0}
}

@article{Hays:1992p9017,
author = {R D Hays and D Hadorn},
journal = {Qual Life Res},
title = {Responsiveness to change: an aspect of validity, not a separate dimension},
abstract = {Assessment of health-related quality of life is accelerating in naturalistic observational studies, clinical trials, and clinical practice. Some researchers have argued that the ability of a quality of life instrument to detect clinically important changes over time, "responsiveness," is a distinct psychometric property from the measure's reliability and validity. We discuss the important implications of this argument and counter that responsiveness is actually one indication of a measure's validity.},
affiliation = {RAND, Social Policy Department, Santa Monica, CA 90407-2138.},
number = {1},
pages = {73--5},
volume = {1},
year = {1992},
month = {Feb},
language = {eng},
keywords = {Questionnaires, Time Factors, Research Design, Psychometrics, Neoplasms, Quality of Life, Reproducibility of Results, Homeless Persons, Life Change Events, Humans},
date-added = {2010-03-22 13:13:48 +0100},
date-modified = {2010-07-29 19:48:30 +0200},
pmid = {1301117},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hays-1992-Qual%20Life%20Res_Responsiveness%20to%20ch.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9017},
rating = {0}
}

@article{Tay:2009p13442,
author = {L Tay and E Diener and F Drasgow and J K Vermunt},
title = {Multilevel mixed-measurement IRT analysis: An explication and application to self-reported emotions around the world},
abstract = {Dimensional approaches assume that all individuals within hierarchical units (e.g., organizations, or countries) share the same measurement model. However, such models are less applicable when researchers are interested in obtaining classes of individuals who share the same measurement model across hierarchical units and to obtain hierarchical latent classes. We present the multilevel mixed-measurement item response theory (MMM-IRT) model as an alternative. This model yields classes of individuals with a common measurement model that span across hierarchical units. Also, hierarchical units are classified together to the extent that they share similar proportions of individual-level classes. We illustrate the MMM-IRT model with data on self-reported emotions from 121,740 individuals across 116 countries where four individual-classes and five country-classes were found. Theoretical and methodological implications concerning cross-cultural, multilevel and measurement equivalence research are discussed.},
year = {2009},
date-added = {2010-07-01 20:06:20 +0200},
date-modified = {2010-07-01 20:07:24 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Tay-2009-_Multilevel%20mixed-mea.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13442},
rating = {0}
}

@article{Hwang:2010p2722,
author = {H Hwang and W R Dillon and Y Takane},
title = {An Extension of Multiple Correspondence Analysis for Identifying Heterogeneous Subgroups of Respondents},
abstract = {An extension of multiple correspondence analysis is proposed that takes into account cluster-level heterogeneity in respondents' preferences/choices. The method involves combining multiple correspondence analysis and k-means in a unified framework. The former is used for uncovering a low-dimensional space of multivariate categorical variables while the latter is used for identifying relatively homogeneous clusters of respondents. The proposed method offers an integrated graphical display that provides information on cluster-based structures inherent in multivariate categorical data as well as the interdependencies among the data. An empirical application is presented which demonstrate the usefulness of the proposed method and how it compares to several extant approaches.},
date-added = {2010-01-13 14:11:54 +0100},
date-modified = {2010-01-13 14:12:52 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hwang--_An%20Extension%20of%20Mult.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2722},
rating = {0}
}

@article{Wayne:2010p8505,
author = {Peter M Wayne and Julie E Buring and Roger B Davis and Ellen M Connors and Paolo Bonato and Benjamin Patritti and Mary Fischer and Gloria Y Yeh and Calvin J Cohen and Danette Carroll and Douglas P Kiel},
journal = {BMC musculoskeletal disorders},
title = {Tai Chi for osteopenic women: design and rationale of a pragmatic randomized controlled trial},
abstract = {ABSTRACT: BACKGROUND: Post-menopausal osteopenic women are at increased risk for skeletal fractures. Current osteopenia treatment guidelines include exercise, however, optimal exercise regimens for attenuating bone mineral density (BMD) loss, or for addressing other fracture-related risk factors (e.g. poor balance, decreased muscle strength) are not well-defined. Tai Chi is an increasingly popular weight bearing mind-body exercise that has been reported to positively impact BMD dynamics and improve postural control, however, current evidence is inconclusive. This study will determine the effectiveness of Tai Chi in reducing rates of bone turnover in post-menopausal osteopenic women, compared with standard care, and will preliminarily explore biomechanical processes that might inform how Tai Chi impacts BMD and associated fracture risks. METHODS: A total of 86 post-menopausal women, aged 45-70y, T-score of the hip and/or spine -1.0 and -2.5, have been recruited from primary care clinics of a large healthcare system based in Boston. They have been randomized to a group-based 9-month Tai Chi program plus standard care or to standard care only. A unique aspect of this trial is its pragmatic design, which allows participants randomized to Tai Chi to choose from a pre-screened list of community-based Tai Chi programs. Interviewers masked to participants' treatment group assess outcomes at baseline and 3 and 9 months after randomization. Primary outcomes are serum markers of bone resorption (C-terminal cross linking telopeptide of type I collagen, bone formation (osteocalcin), and BMD of the lumbar spine and proximal femur (dual-energy X-ray absorptiometry). Secondary outcomes include health-related quality-of-life, exercise behavior, and psychological well-being. In addition, kinetic and kinematic characterization of gait, standing, and rising from a chair are assessed in subset of participants (n=16) to explore the feasibility of modeling skeletal mechanical loads and postural control as mediators of fracture risk. CONCLUSION: Results of this study will provide preliminary evidence regarding the value of Tai Chi as an intervention for decreasing fracture risk in osteopenic women. They will also inform the feasibility, value and potential limitations related to the use of pragmatic designs for the study of Tai Chi and related mind-body exercise. If the results are positive, this will help focus future, more in-depth, research on the most promising potential mechanisms of action identified by this study. Trial registration: This trial is registered in Clinical Trials.gov, with the ID number of NCT01039012.},
number = {1},
pages = {40},
volume = {11},
year = {2010},
month = {Mar},
language = {ENG},
date-added = {2010-03-21 18:07:56 +0100},
date-modified = {2010-03-21 18:07:56 +0100},
doi = {10.1186/1471-2474-11-40},
pii = {1471-2474-11-40},
pmid = {20193083},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wayne-2010-BMC%20musculoskeletal%20disorders_Tai%20Chi%20for%20osteopen.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8505},
rating = {0}
}

@article{Zumbo:2007,
author = {Bruno D Zumbo},
journal = {Language Assessment Quarterly},
title = {Three Generations of DIF Analyses: Considering Where It Has Been, Where It Is Now, and Where It Is Going},
abstract = {The purpose of this article is to reflect on the state of the theorizing and praxis of DIF in general: where it has been; where it is now; and where I think it is, and should, be going. Along the way the major trends in the differential item functioning (DIF) literature are summarized and integrated providing some organizing principles that allow one to catalog and then contrast the various DIF detection methods and to shine a light on the future of DIF analyses. The three generations of DIF are introduced and described with an eye toward issues on the horizon for DIF.},
number = {2},
pages = {223--233},
volume = {4},
year = {2007},
date-added = {2010-01-03 19:38:21 +0100},
date-modified = {2010-07-29 20:46:35 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1144},
read = {Yes},
rating = {0}
}

@article{Zorn:2005p2329,
author = {C Zorn},
journal = {Political Analysis},
title = {A Solution to Separation in Binary Response Models},
abstract = {A common problem in models for dichotomous dependent variables is ``separation,'' which occurs when one or more of a model's covariates perfectly predict some binary outcome. Separation raises a particularly difficult set of issues, often forcing researchers to choose between omitting clearly important covariates and undertaking post--hoc data or estimation corrections. In this article I present a method for solving the separation problem, based on a penalized likelihood correction to the standard binomial GLM score function. I then apply this method to data from an important study on the postwar fate of leaders.},
affiliation = {Law and Social Science Program, National Science Foundation, 4201 Wilson Boulevard, Suite 995, Arlington, VA 22230},
pages = {157--170},
volume = {13},
year = {2005},
date-added = {2010-01-10 13:12:04 +0100},
date-modified = {2010-01-10 13:12:57 +0100},
doi = {10.1093/pan/mpi009},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Zorn-2005-Political%20Analysis_A%20Solution%20to%20Separa.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2329},
rating = {0}
}

@article{Sainfort:1996p5588,
author = {F Sainfort and M Becker and R Diamond},
journal = {Am J Psychiatry},
title = {Judgments of quality of life of individuals with severe mental disorders: Patient self-report versus provider perspectives},
abstract = {OBJECTIVE: This study was an investigation of judgments regarding quality of life of individuals with severe mental disorders from two different perspectives: patient self-report versus provider. METHOD: Judgments on several dimensions of quality of life were collected from a convenience sample of 37 schizophrenic patients and their primary clinicians by using the well-known Quality of Life Index of Spitzer et al. and the more recently developed Quality of Life Index-Mental Health. Both indexes capture judgments on a number of dimensions. Patterns of concordance for the patient-provider pairs were tested by using Cohen's kappa and Pearson correlation coefficients. RESULTS: The results suggest that patients' and providers' judgments are more likely to coincide on clinical aspects, such as symptoms and function, than on social aspects. Specifically, there was moderate agreement on symptoms and function, less agreement on physical health, and little to no agreement on social relations and occupational aspects of quality of life. CONCLUSIONS: Such differences support the notion that treatment strategies and mental health services should address a wide range of needs reflecting different aspects of quality of life perceived as important by different patients.},
affiliation = {Center for Health Systems Research and Analysis, School of Medicine, University of Wisconsin, Madison, USA.},
number = {4},
pages = {497--502},
volume = {153},
year = {1996},
month = {Apr},
language = {eng},
keywords = {Personality Inventory, Chronic Disease, Female, Middle Aged, Psychiatric Status Rating Scales, Psychometrics, Reproducibility of Results, Schizophrenic Psychology, Social Support, Aged, Adult, Activities of Daily Living, Schizophrenia, Quality of Life, Mental Disorders, Multivariate Analysis, Severity of Illness Index, Social Adjustment, Humans, Male, Health Status},
date-added = {2010-02-12 15:38:59 +0100},
date-modified = {2010-07-29 19:51:28 +0200},
pmid = {8599397},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5588},
rating = {0}
}

@book{Durkheim:1951,
author = {E Durkheim},
journal = {Book},
title = {Suicide; A Study in Sociology},
year = {1951},
date-added = {2010-01-03 19:36:09 +0100},
date-modified = {2010-07-29 19:21:41 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1054},
rating = {0}
}

@article{Grimm:2009p492,
author = {Kevin J Grimm and Robert C Pianta and Timothy Konold},
journal = {Multivariate Behavioral Research},
title = {Longitudinal Multitrait-Multimethod Models for Developmental Research},
abstract = {Multitrait-multimethod (MTMM) confirmatory factor models were combined with longitudinal structural equation models to examine trait and method stability over time. A longitudinal correlated-trait correlated-method (CT-CM) model allowed for the study of trait and method variance in observed scores over time. Longitudinal measurement invariance was examined in the longitudinal CT-CM model to deter- mine the invariance of the trait and method factors. The longitudinal MTMM model was then combined with second-order latent curve models to evaluate within-person change and between-person differences change in the trait factors while accounting for method-related variance. These models were developed and applied to longitudinal behavior-rating data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development with externalizing, internalizing, and social skills serving as the traits and mother, father, and teacher serving as methods or informants. Methodological extensions of longitudinal MTMM models and benefits of an MTMM approach to developmental research are discussed.},
pages = {233--258},
volume = {44},
year = {2009},
date-added = {2010-01-03 12:56:01 +0100},
date-modified = {2010-01-03 12:57:52 +0100},
doi = {10.1080/00273170902794230},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Grimm-2009-Multivariate%20Behavioral%20Research_Longitudinal%20Multitr.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p492},
rating = {0}
}

@article{Bearden:2009p5939,
author = {Carrie E Bearden and Anna J Jasinska and Nelson B Freimer},
journal = {Annual review of clinical psychology},
title = {Methodological issues in molecular genetic studies of mental disorders},
abstract = {The development of methodologies for assaying genetic variation at high resolution throughout the genome has revolutionized the search for susceptibility genes for common diseases. This search, however, has been less successful in psychiatry than in other areas of medicine. It is hypothesized that the imprecision and uncertain validity of psychiatric diagnoses are major factors in this disappointing progress. Here we discuss the methodologies employed for genetic investigation of mental disorders, including phenotyping strategies, approaches to genetic mapping, and use of animal models of psychopathology.},
affiliation = {Department of Psychiatry {\&} Biobehavioral Sciences, University of California-Los Angeles, CA 90095, USA. cbearden@mednet.ucla.edu},
pages = {49--69},
volume = {5},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Psychiatry, Linkage (Genetics), Humans, Chromosome Mapping, Phenotype, Mental Disorders, Genetic Variation, Molecular Biology},
date-added = {2010-02-18 23:16:26 +0100},
date-modified = {2010-02-18 23:16:26 +0100},
doi = {10.1146/annurev.clinpsy.032408.153545},
pmid = {19327025},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bearden-2009-Annual%20review%20of%20clinical%20psychology_Methodological%20issue.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5939},
rating = {0}
}

@article{VanGestel:2003p3019,
author = {S Van Gestel and C Van Broeckhoven},
journal = {Mol Psychiatry},
title = {Genetics of personality: are we making progress?},
abstract = {For centuries, scientists are intrigued by the differences in personality between individuals. As early as in the ancient Greek civilization, people tried to formulate theories to systematize this diversity. With the increased interest in behavior genetics, personality was also considered a challenging phenotype. From the early start, studies suggested a heritable component in personality. After the successes of molecular genetic studies in unraveling the genetic basis of (mostly) monogenic diseases, the focus shifted towards complex traits, including psychiatric disorders. It was observed in several studies that personality measures differed between patients with psychiatric disorders and healthy controls. Therefore, normal personality was considered a viable endophenotype in the search for genes involved in psychiatric disorders such as affective disorders, ADHD and substance dependence. Genes that were to be found in studies on personality could be candidate genes for particular psychiatric disorders. In the course of time, however the study of genes for personality turned out to be at least as hard as the search for genes involved in other complex disorders. In this review, past studies, present problems and future directions concerning the study of personality genetics are discussed.},
affiliation = {Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology (VIB8), University of Antwerp (UIA), Antwerpen, Belgium.},
number = {10},
pages = {840--52},
volume = {8},
year = {2003},
month = {Oct},
language = {eng},
keywords = {Humans, Biological Psychiatry, Molecular Biology, Personality},
date-added = {2010-01-14 11:23:49 +0100},
date-modified = {2010-01-14 11:23:49 +0100},
doi = {10.1038/sj.mp.4001367},
pii = {4001367},
pmid = {14515135},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Van%20Gestel-2003-Mol%20Psychiatry_Genetics%20of%20personal.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3019},
rating = {0}
}

@article{Congdon:2001p6013,
author = {P Congdon},
journal = {Health Place},
title = {Health status and healthy life measures for population health need assessment: modelling variability and uncertainty},
abstract = {It is increasingly recognised that population health need assessments based on the comparison of clinical or demographic end points (e.g. area mortality rates) neglect population variation in broader aspects of health status and health-related quality of life. Similarly, outcome measures which neglect impacts on health-related quality of life may be an inadequate basis for assessing the effectiveness of health interventions. This paper reviews issues in assessing needs and outcomes at population level based on health status valuations. It considers especially the modelling of sources of uncertainty in measures of health status by using Bayesian sampling estimation methods which produce a distribution of summary outcome measures. The modelling issues are illustrated in models for individual level health status from survey responses and their incorporation in area life tables to derive total and healthy life expectancies. In particular, a health status index derived from Short Form 36 profile responses in a health and lifestyle survey in a London health authority provides a case study of community health needs assessment.},
affiliation = {Department of Geography, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK.},
number = {1},
pages = {13--25},
volume = {7},
year = {2001},
month = {Mar},
language = {eng},
keywords = {Aged, Needs Assessment, Adolescent, Small-Area Analysis, Quality-Adjusted Life Years, Models: Statistical, Aged: 80 and over, Middle Aged, Bayes Theorem, Health Status, London, Adult, Age Distribution, Community Health Planning, Humans, Organizational Case Studies},
date-added = {2010-02-18 23:36:09 +0100},
date-modified = {2010-02-18 23:36:09 +0100},
pii = {S1353-8292(00)00034-4},
pmid = {11165152},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6013},
rating = {0}
}

@article{Fienberg:1996p6311,
author = {S E Fienberg and J M Tanur},
journal = {International Statistical Review},
title = {Reconsidering the Fundamental Contributions of Fisher and Neyman on Experimentation and Sampling},
abstract = {R.A. Fisher and Jerzy Neyman are commonly acknowledged as the statisticians who provided the
basic ideas that underpin the design of experiments and the design of sample surveys, respectively. In this paper, we reconsider the key contributions of these great men to the two areas of research. We also
explain how the controversy surrounding Neyman's 1935 paper on agricultural experimentation in effect led to a split in research on experiments and on sample surveys.},
number = {3},
pages = {237--253},
volume = {64},
year = {1996},
date-added = {2010-02-20 21:05:46 +0100},
date-modified = {2010-02-20 21:06:41 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fienberg-1996-International%20Statistical%20Review_Reconsidering%20the%20Fu.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6311},
rating = {0}
}

@article{Kirisci:2006p264,
author = {Levent Kirisci and Ralph E Tarter and Michael Vanyukov and Chris Martin and Ada Mezzich and Stacy Brown},
journal = {Addict Behav},
title = {Application of item response theory to quantify substance use disorder severity},
abstract = {Objective: The present investigation had two main goals: (1) Determine whether binary substance use disorder (SUD) diagnoses are indicators of a unidimensional trait indexing severity of disorder; and, (2) demonstrate the predictive, concurrent and construct validity of the SUD severity scale. Methods: Boys and their biological parents were administered structured diagnostic interviews to diagnose SUD. Item response theory (IRT) was applied to determine whether the diagnoses are indicators of a unidimensional trait. The score on this scale was correlated with substance use behavior, violence, treatment history, risky sex, and social adjustment.
Results: SUD diagnoses are indicators of a unidimensional latent trait. Maternal and paternal SUD severity predicted son's SUD severity at age 19. The score on the SUD severity scale correlated with drug use frequency, number of different drugs used in lifetime, treatment seeking, illegal behavior, social maladjustment, and risky sex.
Conclusion: SUD can be quantified on an interval scale indexing severity of disorder. The advantages of measuring SUD severity as a continuous trait are discussed.},
affiliation = {Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA},
pages = {1035--1049},
volume = {31},
year = {2006},
month = {May},
date-added = {2010-01-03 10:59:00 +0100},
date-modified = {2010-01-03 11:01:36 +0100},
doi = {10.1016/j.addbeh.2006.03.033},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kirisci-2006-Addictive%20Behaviors_Application%20of%20item.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p264},
rating = {0}
}

@article{Dick:2007p10475,
author = {Danielle M Dick and Fazil Aliev and John Kramer and Jen C Wang and Anthony Hinrichs and Sarah Bertelsen and Sam Kuperman and Marc Schuckit and John Nurnberger and Howard J Edenberg and Bernice Porjesz and Henri Begleiter and Victor Hesselbrock and Alison Goate and Laura Bierut},
journal = {Behav Genet},
title = {Association of CHRM2 with IQ: converging evidence for a gene influencing intelligence},
abstract = {The cholinergic neurotransmitter system is thought to be involved in many aspects of memory, attention, and higher cognition. In the Collaborative Study on the Genetics of Alcoholism (COGA) sample, we have previously reported linkage and association to the cholinergic muscarinic 2 receptor gene (CHRM2) on chromosome 7 with evoked EEG oscillations (Jones et al. 2004), providing evidence that this gene may be involved in human brain dynamics and cognition. In addition, a small number of genetic markers were genotyped in CHRM2 in the Minnesota Twin and Family Study (Comings et al. 2003) and a Dutch family study (Gosso et al. 2006, in press) and both research groups found evidence that this gene may be involved in intelligence. In the COGA sample, we have extensively genotyped SNPs within and flanking the CHRM2 gene. We find evidence of association with multiple SNPs across CHRM2 and Performance IQ, as measured by the Wechsler Adult Intelligence Scale-Revised (WAIS-R). These results remain significant after taking into account alcohol dependence and depression diagnoses in the sample.},
affiliation = {Department of Psychiatry, Washington University in St. Louis, 660 South Euclid Ave., Box 8134, St. Louis, MO 63130, USA. dickd@psychiatry.wustl.edu},
number = {2},
pages = {265--72},
volume = {37},
year = {2007},
month = {Mar},
language = {eng},
keywords = {Genotype, Family, Chromosome Mapping, Humans, Receptor: Muscarinic M2, Male, Chromosomes: Human: Pair 7, Intelligence, Twin Studies as Topic, Alcoholism, United States, Wechsler Scales, Female, Polymorphism: Single Nucleotide},
date-added = {2010-04-07 11:08:08 +0200},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-006-9131-2},
pmid = {17160701},
URL = {http://www.springerlink.com/content/h4v46j012v011315/},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Dick-2007-Behav%20Genet_Association%20of%20CHRM2.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10475},
rating = {0}
}

@article{Wu:2006p2770,
author = {M Wu and R J Adams},
journal = {Mathematics Education Research Journal},
title = {Modelling Mathematics Problem Solving Item Responses Using a Multidimensional IRT Model},
abstract = {This research examined students' responses to mathematics problem-solving tasks and applied a general multidimensional IRT model at the response category level. In doing so, cognitive processes were identified and modelled through item response modelling to extract more information than would be provided using conventional practices in scoring items. More specifically, the study consisted of two parts. The first part involved the development of a mathematics problem-solving framework that was theoretically grounded, drawing upon research in mathematics education and cognitive psychology. The framework was then used as the basis for item development. The second part of the research involved the analysis of the item response data. It was demonstrated that multidimensional IRT models were powerful tools for extracting information from a limited number of item responses. A problem-solving profile for each student could be constructed from the results of IRT scaling.},
number = {2},
pages = {93--113},
volume = {18},
year = {2006},
date-added = {2010-01-13 14:26:48 +0100},
date-modified = {2010-07-29 20:16:39 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wu-2006-Mathematics%20Education%20Research%20Journal_Modelling%20Mathematic-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2770},
rating = {0}
}

@article{KraljNovak:2009p2382,
author = {Petra Kralj Novak and Nada Lavrac and Dragan Gamberger and Antonija Krstaci{\'c}},
journal = {J Biomed Inform},
title = {CSM-SD: methodology for contrast set mining through subgroup discovery},
abstract = {This paper addresses a data analysis task, known as contrast set mining, whose goal is to find differences between contrasting groups. As a methodological novelty, it is shown that this task can be effectively solved by transforming it to a more common and well-understood subgroup discovery task. The transformation is studied in two learning settings, a one-versus-all and a pairwise contrast set mining setting, uncovering the conditions for each of the two choices. Moreover, the paper shows that the explanatory potential of discovered contrast sets can be improved by offering additional contrast set descriptors, called the supporting factors. The proposed methodology has been applied to uncover distinguishing characteristics of two groups of brain stroke patients, both with rapidly developing loss of brain function due to ischemia:those with ischemia caused by thrombosis and by embolism, respectively.},
affiliation = {Department of Knowledge Technologies, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia. Petra.Kralj@ijs.si},
number = {1},
pages = {113--22},
volume = {42},
year = {2009},
month = {Feb},
language = {eng},
keywords = {Artificial Intelligence, Decision Trees, Medical Records Systems: Computerized, Statistics: Nonparametric, Intracranial Thrombosis, Brain Ischemia, Risk Factors, Algorithms, Prognosis, Chi-Square Distribution, Information Storage and Retrieval, Intracranial Embolism, Pattern Recognition: Automated, Humans},
date-added = {2010-01-10 19:32:06 +0100},
date-modified = {2010-01-10 19:32:06 +0100},
doi = {10.1016/j.jbi.2008.08.007},
pii = {S1532-0464(08)00103-2},
pmid = {18782633},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kralj%20Novak-2009-J%20Biomed%20Inform_CSM-SD%20methodology.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2382},
rating = {0}
}

@article{Vittinghoff:2009p6908,
author = {E Vittinghoff and S Sen and C E McCulloch},
journal = {Stat Med},
title = {Sample size calculations for evaluating mediation},
abstract = {This paper presents sample size calculations for testing the mediation of the effect of a primary predictor by an intermediate variable. This problem is related to validating surrogate markers and to testing the effect of a primary predictor in the presence of confounders. For those problems, proposals for sample size calculation exist in the literature and can be adapted to the problem of mediation. Methods based on the variance inflation factor in linear regression provide exact sample size calculations for the linear model and approximations for the logistic, Poisson, and Cox models. We propose another procedure based on simulation of the underlying data structure, with applications to the logistic and Cox models. For the Poisson model, a new analytic method is also proposed. The behavior of the different proposals is investigated by means of simulation studies.},
affiliation = {Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA. eric@biostat.ucsf.edu},
number = {4},
pages = {541--57},
volume = {28},
year = {2009},
month = {Feb},
language = {eng},
keywords = {Logistic Models, Confounding Factors (Epidemiology), Computer Simulation, Linear Models, Proportional Hazards Models, Sample Size, Poisson Distribution},
date-added = {2010-03-06 12:22:46 +0100},
date-modified = {2010-03-06 12:22:46 +0100},
doi = {10.1002/sim.3491},
pmid = {19065627},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Vittinghoff-2009-Stat%20Med_Sample%20size%20calculat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6908},
rating = {0}
}

@article{Hageman:1999,
author = {WJ Hageman and Arrindell WA},
journal = {Behavior Research and Therapy},
title = {Establishing clinically significant change: increment of precision and the distinction between individual and group level of analysis.},
abstract = {Some essential adaptations to the method for determining clinically significant change originally introduced by Jacobson, Follette and Revenstorf [Jacobson, N. S., Follette, W. C. {\&} Revenstorf, D. (1984a). Psychotherapy outcome research: methods for reporting variability and evaluating clinical significance. Behavior Therapy, 15, 336-352.] are presented. One adaptation deals with the failure in the original method to distinguish between analysis at the individual versus analysis at the group level. A second adaptation entails the provision of a closer approximation of the underlying true scores. This refinement represents an enhancement in precision. Specific aspects of this refinement may be understood in terms of a correction for error-based regression to the mean. Taking into account these adaptations, new procedures are described for determining (clinically significant) change. Some guidelines for the publication of outcome findings are also presented.},
number = {12},
pages = {1169--1193},
volume = {37},
year = {1999},
date-added = {2010-01-03 19:35:29 +0100},
date-modified = {2010-01-03 19:35:29 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1022},
rating = {0}
}

@article{Buja:2004p2717,
author = {A Buja and D F Swayne and M L Littman and N Dean},
title = {Interactive Data Visualization with Multidimensional Scaling},
abstract = {We discuss interactive techniques for multidimensional scaling (MDS) and a two sys- tems, named ``GGvis'' and ``XGvis'', that implement these techniques.
MDS is a method for visualizing proximity data, that is, data where objects are char- acterized by dissimilarity values for all pairs of objects. MDS constructs maps (called ``configurations'') of these objects in IRk by interpreting the dissimilarities as distances.
As a data-mapping technique, MDS is fundamentally a visualization method. It is hence plausible that MDS gains in power if it is embedded in a data visualization environment. Consequently, the MDS systems presented here are conceived as exten- sions of multivariate data visualization systems (``GGvis'' and ``X/GGobi'' in this case). The visual analysis of MDS output profits from dynamic projection tools for viewing high-dimensional configurations, from brushing multiple linked views, from plot en- hancements such as labels, glyphs, colors, lines, and from selective removal of groups of objects. Powerful is also the ability to move points and groups of points interactively and thereby create new starting configurations for MDS optimization.
In addition to the benefits of a data visualization environment, we enhance MDS by providing interactive control over numerous options and parameters, a few of them novel. They include choices of 1) metric versus nonmetric MDS, 2) classical versus dis- tance MDS, 3) the configuration dimension, 4) power transformations for metric MDS, 5) distance transformations and 6) Minkowski metrics for distance MDS, 7) weights in the form of powers of dissimilarities and 8) as a function of group memberships, 9) var- ious types of group-dependent MDS such as multidimensional unfolding and external unfolding, 10) random subselection of dissimilarities, 11) perturbation of configura- tions, and 12) a separate window for diagnostics, including the Shepard plot.
MDS was originally developed for the social sciences, but it is now also used for laying out graphs. Graph layout is usually done in 2-D, but we allow layouts in arbitrary dimensions. We show applications to the mapping of computer usage data, to the dimension reduction of marketing segmentation data, to the layout of mathematical graphs and social networks, and finally to the spatial reconstruction of molecules.},
year = {2004},
date-added = {2010-01-13 14:03:53 +0100},
date-modified = {2010-01-13 14:04:47 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Buja-2004-_Interactive%20Data%20Vis-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2717},
rating = {0}
}

@article{Stryker:2006,
author = {JE Stryker and RJ Wray and KM Emmons and E Winer and G Demetri},
journal = {Patient Education and Counseling},
title = {Understanding the decisions of cancer clinical trial participants to enter research studies: Factors associated with informed consent, patient satisfaction, and decisional regret},
abstract = {Objective To understand the psychosocial outcomes related to decision-making processes of individuals eligible for participation in clinical trials. Methods Individuals eligible to participate in selected clinical trials were contacted to complete two surveys; one shortly after participants were identified, and the second 6 weeks after the first survey was completed (N = 50). Measures included subjective informed consent; satisfaction with decision-making; decisional regret; and timing of consent (early versus late signers). ANOVA and correlation coefficients were used to test the relationships between variables. Results Early signers reported themselves to be less informed about the details of their particular clinical trials than later signers (M = 81.9 versus 91.2; F = 5.5; p = .02). There was a non-significant trend for early signers to be less satisfied with their decisions than late signers. Satisfaction with decision-making and subjective informed consent were both strongly associated with later decisional regret (r = -.32 and -.30, respectively). However, there was no relationship between timing of consent and decisional regret. Conclusion Participants who enroll in clinical trials quickly may not believe they fully understand the implications of trial participation. In general, participants who do not believe they fully understand the implications of trial participation, or who are less satisfied with their decision to enroll in the trial may ultimately feel regret about their decision to participate. Practice implications More effort is needed to ensure that clinical trial participants fully understand the risks and benefits of participation and are satisfied with their decision to enroll in a trial prior to signing consent forms.},
number = {1-2},
pages = {104--109},
volume = {63},
year = {2006},
date-added = {2010-01-03 19:34:17 +0100},
date-modified = {2010-01-03 19:34:18 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p956},
rating = {0}
}

@article{Carvalho:2010p6618,
author = {C Carvalho and J Chang and J Lucas and J R Nevins and Q Wang and M West},
title = {High-Dimensional Sparse Factor Modelling: Applications in Gene Expression Genomics},
abstract = {In studies of molecular profiling and biological pathway analysis using DNA microarray gene expression data we are utilising a broad class of sparse latent factor and regression models for large-scale multivariate analysis and regression prediction. We present examples of these applica- tions with discussion of key aspects of the modelling and computational methodology. Our case studies are drawn from breast cancer genomics, where we are concerned with the investigation and characterisation of heterogeneity of structure related to specific oncogenic pathways, as well as predictive/prognostic uses of aggregate patterns in gene expression profiles in clinical contexts. Based on the metaphor of statistically derived ``factors'' as representing biological ``subpathway'' structure, we explore the decomposition of fitted sparse factor models into pathway subcompo- nents, and how these components overlay multiple aspects of known biological structure in this network. We discuss the discovery and predictive uses of this approach, and the ability to use such models to generate enrichment of existing biological descriptions through identification of interactions between factors and subsequent experimental validation. We further illustrate the cou- pled use of predictive factor regression models with the high-dimensional sparse factor analysis of expression profiles.
Our methodology is based on sparsity modelling of multivariate regression, anova and latent factor models, and a general class of models that combines all components. Novel and effec- tive sparsity priors address the inherent questions of dimension reduction and multiple compar- isons, as well as scalability of the methodology. The models include practically relevant non- Gaussian/non-parametric components for modelling latent structure underlying often quite com- plex non-Gaussianity in multivariate expression patterns related to underlying biology. Model search and fitting are addressed through stochastic simulation and evolutionary stochastic search methods that are exemplified in oncogenic pathway studies. Supplementary supporting material provides more details of the applications as well as examples of the use of freely available soft- ware tools implementing the methodology.},
date-added = {2010-03-03 20:28:23 +0100},
date-modified = {2010-03-03 20:29:36 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Carvalho--_High-Dimensional%20Spa-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6618},
rating = {0}
}

@article{Tashakkori:1989p5519,
author = {A Tashakkori and J Barefoot and A H Mehryar},
journal = {J Clin Psychol},
title = {What does the Beck Depression Inventory measure in college students? Evidence from a non-western culture},
abstract = {This investigation of the factor structure of the Beck Depression Inventory (BDI) was designed to assess Gotlib's (1984) claim that the BDI is more a measure of general psychopathology than a specific measure of depression when administered to student samples. The data were collected from Iranian students and provide further information about the performance of the BDI in a non-Western culture. Principal components analysis of the responses to items 1-20 of the BDI (N = 405) revealed five factors with different degrees of similarity to findings of Hill, Kemp-Wheeler, and Jones (1986). Within subsamples, the factor scores were predicted in multiple regression analysis from Eysenck Personality Inventory subscales (N, P, E, L), James' I-E scale, and two measures of self-esteem. Results indicated that the five factors had distinctly different relationships to the other personality scales. The most general factor seemed to be a measure of helplessness and self-devaluation. These results confirm the usefulness of the BDI as a measure of depression in college student populations, even in non-Western cultures.},
affiliation = {Department of Psychology, Stetson University, DeLand, FL 32720.},
number = {4},
pages = {595--602},
volume = {45},
year = {1989},
month = {Jul},
language = {eng},
keywords = {Iran, Female, Cross-Cultural Comparison, Adult, Depression, Psychological Tests, Humans, Self Concept, Personality Inventory, Internal-External Control, Male, Students, Psychometrics},
date-added = {2010-02-12 14:59:32 +0100},
date-modified = {2010-02-12 14:59:32 +0100},
pmid = {2768499},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5519},
rating = {0}
}

@article{Burns:2009p2321,
author = {P Burns},
title = {The R Inferno},
year = {2009},
date-added = {2010-01-10 12:44:22 +0100},
date-modified = {2010-01-10 12:44:52 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Burns-2009-_The%20R%20Inferno.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2321},
rating = {0}
}

@article{Iacono:2003p9097,
author = {William G Iacono and Stephen M Malone and Matt McGue},
journal = {Int J Psychophysiol},
title = {Substance use disorders, externalizing psychopathology, and P300 event-related potential amplitude},
abstract = {We hypothesize the existence of an inherited predisposition for a spectrum of behaviors and traits characterized by behavioral disinhibition. This externalizing spectrum includes childhood disruptive disorders, antisocial behavior, substance use disorders, personality traits related to behavioral undercontrol, and the precocious expression of problem behavior. We further hypothesize that a genetically influenced central nervous system diathesis underlies this spectrum and is reflected in reduced P300 amplitude in a visual oddball event-related potential task. A review of evidence bearing on the model is derived from findings from the Minnesota Twin Family Study, a population-based, longitudinal investigation of twin youth. These findings indicate that the collection of attributes related to behavioral disinhibition is familial, heritable, and interrelated. Evidence supporting P3 amplitude reduction (P3-AR) as an index of genetic vulnerability for this externalizing spectrum includes its association with (a) familial risk for substance use and antisocial personality disorders, (b) diagnoses of childhood disruptive disorders and substance use disorders, (c) early onset of undersocialized behavior, and (d) quantitative phenotypes related to externalizing problems. In addition, the development of substance use disorders over a 3-year period is associated with P3-AR measured prior to their expression. These findings suggest that P3-AR indexes one aspect of the genetic diathesis for a spectrum of externalizing problem behavior.},
affiliation = {Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA. wiacono@tfs.psych.umn.edu},
number = {2},
pages = {147--78},
volume = {48},
year = {2003},
month = {May},
language = {eng},
keywords = {Phenotype, Reaction Time, Psychopathology, Child Behavior Disorders, Substance-Related Disorders, Environment, Family Health, Antisocial Personality Disorder, Male, Female, Causality, Adolescent, Sex Factors, Psychiatric Status Rating Scales, Personality Assessment, Humans, Event-Related Potentials: P300, Twin Studies as Topic, Diagnosis: Dual (Psychiatry), Child},
date-added = {2010-03-22 13:24:45 +0100},
date-modified = {2010-03-22 13:24:45 +0100},
pii = {S0167876003000527},
pmid = {12763572},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Iacono-2003-Int%20J%20Psychophysiol_Substance%20use%20disord.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9097},
rating = {0}
}

@article{Barth:2010p9818,
author = {Andreas S Barth and Ami Kumordzie and Carlo Colantuoni and Kenneth B Margulies and Thomas P Cappola and Gordon F Tomaselli},
journal = {BMC Genomics},
title = {Reciprocal regulation of metabolic and signaling pathways},
abstract = {ABSTRACT: BACKGROUND: By studying genome-wide expression patterns in healthy and diseased tissues across a wide range of pathophysiological conditions, DNA microarrays have revealed unique insights into complex diseases. However, the high-dimensionality of microarray data makes interpretation of heterogeneous gene expression studies inherently difficult. RESULTS: Using a large-scale analysis of more than 40 microarray studies encompassing ~2400 mammalian tissue samples, we identified a common theme across heterogeneous microarray studies evident by a robust genome-wide inverse regulation of metabolic and cell signaling pathways: We found that upregulation of cell signaling pathways was invariably accompanied by downregulation of cell metabolic transcriptional activity (and vice versa). Several findings suggest that this characteristic gene expression pattern represents a new principle of mammalian transcriptional regulation. First, this coordinated transcriptional pattern occurred in a wide variety of physiological and pathophysiological conditions and was identified across all 20 human and animal tissue types examined. Second, the differences in metabolic gene expression predicted the magnitude of differences for signaling and all other pathways, i.e. tissue samples with similar expression levels of metabolic transcripts did not show any differences in gene expression for all other pathways. Third, this transcriptional pattern predicted a profound effect on the proteome, evident by differences in structure, stability and post-translational modifications of proteins belonging to signaling and metabolic pathways, respectively. CONCLUSIONS: Our data suggest that in a wide range of physiological and pathophysiological conditions, gene expression changes exhibit a recurring pattern along a transcriptional axis, characterized by an inverse regulation of major metabolic and cell signaling pathways. Given its widespread occurrence and its predicted effects on protein structure, protein stability and post-translational modifications, we propose a new principle for transcriptional regulation in mammalian biology.},
number = {1},
pages = {197},
volume = {11},
year = {2010},
month = {Mar},
language = {ENG},
date-added = {2010-03-26 19:22:03 +0100},
date-modified = {2010-03-26 19:22:04 +0100},
doi = {10.1186/1471-2164-11-197},
pii = {1471-2164-11-197},
pmid = {20334672},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Barth-2010-BMC%20Genomics_Reciprocal%20regulatio-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9818},
rating = {0}
}

@article{Kieseppa:2004p7519,
author = {Tuula Kiesepp{\"a} and Timo Partonen and Jari Haukka and Jaakko Kaprio and Jouko L{\"o}nnqvist},
journal = {Am J Psychiatry},
title = {High concordance of bipolar I disorder in a nationwide sample of twins},
abstract = {OBJECTIVE: The few studies of bipolar I disorder in twins have consistently emphasized the genetic contribution to disease liability. The authors report what appears to be the first twin study of bipolar I disorder involving a population-based twin sample, in which the diagnoses were made by using structured, personal interviews. METHOD: All Finnish same-sex twins (N=19,124) born from 1940 to 1957 were screened for a diagnosis of bipolar I disorder as recorded in the National Hospital Discharge Register between 1969 and 1991 or self-reported in surveys of the Finnish Twin Cohort in 1975, 1981, and 1990. Thirty-eight pairs were thereby identified and invited to participate in the study; the participation rate was 68%. Lifetime diagnoses were made by using the Structured Clinical Interview for DSM-IV. The authors calculated probandwise and pairwise concordances and correlations in liability and applied biometrical model fitting. RESULTS: The probandwise concordance rates were 0.43 (95% CI=0.10 to 0.82) for monozygotic twins and 0.06 (95% CI=0.00 to 0.27) for dizygotic twins. The correlations in liability were 0.85 and 0.41, respectively. The model with no familial transmission was rejected. The best-fitting model was the one in which genetic and specific environmental factors explained the variance in liability, with a heritability estimate of 0.93 (95% CI=0.69 to 1.00). CONCLUSIONS: The high heritability of bipolar disorder was demonstrated in a nationwide population-based twin sample assessed with structured personal interviews.},
affiliation = {Department of Mental Health and Alcohol Research, National Public Health Institute, 00300 Helsinki 30, Finland. tuula.kieseppa@ktl.fi.},
number = {10},
pages = {1814--21},
volume = {161},
year = {2004},
month = {Oct},
language = {eng},
keywords = {Genetic Testing, Twins: Monozygotic, Adult, Male, Cohort Studies, Social Environment, Prevalence, Risk Factors, Genetic Predisposition to Disease, Female, Registries, Humans, Sex Factors, Models: Genetic, Diseases in Twins, Twins: Dizygotic, Psychiatric Status Rating Scales, Middle Aged, Finland, Psychometrics, Bipolar Disorder},
date-added = {2010-03-14 10:51:25 +0100},
date-modified = {2010-03-14 10:51:25 +0100},
doi = {10.1176/appi.ajp.161.10.1814},
pii = {161/10/1814},
pmid = {15465978},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kiesepp%C3%A4-2004-Am%20J%20Psychiatry_High%20concordance%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7519},
rating = {0}
}

@article{Chatelin:2002p4088,
author = {Y M Chatelin and V Esposito Vinzi and M Tenenhaus},
title = {State-of-art on PLS Path Modeling through the available software},
year = {2002},
date-added = {2010-01-19 20:02:13 +0100},
date-modified = {2010-01-19 20:03:05 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Chatelin-2002-_State-of-art%20on%20PLS.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4088},
rating = {0}
}

@article{Javaras:2009p4944,
author = {K N Javaras and J I Hudson and N M Laird},
journal = {Genet Epidemiol},
title = {Fitting ACE structural equation models to case-control family data},
abstract = {Investigators interested in whether a disease aggregates in families often collect case-control family data, which consist of disease status and covariate information for members of families selected via case or control probands. Here, we focus on the use of case-control family data to investigate the relative contributions to the disease of additive genetic effects (A), shared family environment (C), and unique environment (E). We describe an ACE model for binary family data; this structural equation model, which has been described previously, combines a general-family extension of the classic ACE twin model with a (possibly covariate-specific) liability-threshold model for binary outcomes. We then introduce our contribution, a likelihood-based approach to fitting the model to singly ascertained case-control family data. The approach, which involves conditioning on the proband's disease status and also setting prevalence equal to a prespecified value that can be estimated from the data, makes it possible to obtain valid estimates of the A, C, and E variance components from case-control (rather than only from population-based) family data. In fact, simulation experiments suggest that our approach to fitting yields approximately unbiased estimates of the A, C, and E variance components, provided that certain commonly made assumptions hold. Further, when our approach is used to fit the ACE model to Austrian case-control family data on depression, the resulting estimate of heritability is very similar to those from previous analyses of twin data. Genet. Epidemiol. 2009. (c) 2009 Wiley-Liss, Inc.},
affiliation = {Waisman Laboratory for Brain Imaging {\&} Behavior, University of Wisconsin-Madison, Madison, Wisconsin.},
pages = {},
year = {2009},
month = {Nov},
language = {ENG},
date-added = {2010-02-03 20:59:18 +0100},
date-modified = {2010-02-03 20:59:18 +0100},
doi = {10.1002/gepi.20454},
pmid = {19918760},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Javaras-2009-Genet%20Epidemiol_Fitting%20ACE%20structur.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4944},
rating = {0}
}

@article{Gooding:2010p14052,
author = {Diane Carol Gooding and Madeline Johnson and Joel Stephen Peterman},
journal = {Psychiatry Res},
title = {Schizotypy and altered digit ratios: a second look},
abstract = {Alterations in the ratio between the 2nd and 4th finger digits have been posited as a potential indicator of increased liability for neurodevelopmental disorders such as autism and schizophrenia. We compared digit ratios in two groups of psychometrically-identified schizotypes, namely, those characterized by positive schizotypy (perceptual aberrations and magical ideation; n=76) and those characterized by negative schizotypy (social anhedonia; n=64), to a control group (n=110). The groups were also compared in terms of their performance on a measure of Theory of Mind, namely, the Reading the Mind in the Eyes Test (RMET) and trait affect, as measured by the PANAS. Our results indicate that neither negative schizotypy nor positive schizotypy is associated with altered digit ratios. Similarly, the groups showed no significant differences on the RMET. However, we observed a small but significant inverse association between Theory of Mind performance and negative affect. The findings are considered in light of the extant literature. These results call into question the viability of altered digit ratios to serve as an indicator of increased risk for schizophrenia-spectrum disorders.},
affiliation = {University of Wisconsin-Madison, Department of Psychology, Madison, WI 53706, USA. dgooding@wisc.edu},
number = {1},
pages = {73--8},
volume = {178},
year = {2010},
month = {Jun},
language = {eng},
date-added = {2010-08-18 10:00:09 +0200},
date-modified = {2010-08-18 10:00:09 +0200},
doi = {10.1016/j.psychres.2010.04.023},
pii = {S0165-1781(10)00182-4},
pmid = {20471104},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gooding-2010-Psychiatry%20Res_Schizotypy%20and%20alter.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14052},
rating = {0}
}

@article{Panksepp:2006p3053,
author = {Jaak Panksepp},
journal = {Prog Neuropsychopharmacol Biol Psychiatry},
title = {Emotional endophenotypes in evolutionary psychiatry},
abstract = {Evolutionary psychiatry emerged from the conceptual successes of sociobiology and evolutionary psychology. It will need to avoid the many mistakes that biology-free Evolutionary Psychology has been prey to. It should not ignore the wealth of information that exists between the phenotypic expression of symptoms and the genotypic sources of core brain/mind processes that are disrupted in psychiatric disorders. Syndromal-conceptual thinking has become a barrier to illuminating the biological sources of psychiatric disorders. Endophenoytpic-biomarker approaches now offer robust alternatives for generating linkages between psychiatrically relevant psychological changes and the neurobiological infrastructure of disordered mentation. Here I summarize recent advances in endophenotypic thinking in biological psychiatry, and suggest that various core emotional-affective processes may be among the most important endophenotypes that need to be clarified at both neurobiological and genetic levels of analysis. To this end, I discuss strategies to link basic emotional processes that are commonly imbalanced in psychiatric disorders to neuroanatomical, neurochemical, neurophysiology, and molecular genetic levels of analysis. Conjoint animal behavioral-genetic and gene expression, microarray analyses can clarify a variety of key emotional endophenotypes and thereby provide a coherent infrastructure for psychiatric systematics. To further clarify the neurobiological dimensions of psychiatric disorders, we must also focus on psychosocial and environmental stress vectors that converge to create imbalanced emotional and motivational brain activities of psychiatric significance.},
affiliation = {Center for the Study of Animal Well-Being, College of Veterinary Medicine (VCAPP), Washington State University, Pullman, Washington, USA.},
number = {5},
pages = {774--84},
volume = {30},
year = {2006},
month = {Jul},
language = {eng},
keywords = {Brain Chemistry, Psychiatry, Emotions, Humans, Neurosciences, Animals, Mental Disorders, Evolution, Phenotype},
date-added = {2010-01-14 11:26:08 +0100},
date-modified = {2010-01-14 11:26:08 +0100},
doi = {10.1016/j.pnpbp.2006.01.004},
pii = {S0278-5846(06)00005-4},
pmid = {16554114},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Panksepp-2006-Prog%20Neuropsychopharmacol%20Biol%20Psychiatry_Emotional%20endophenot.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3053},
rating = {3}
}

@article{Rosenberg:2005p6506,
author = {Noah A Rosenberg and Saurabh Mahajan and Sohini Ramachandran and Chengfeng Zhao and Jonathan K Pritchard and Marcus W Feldman},
journal = {PLoS Genet},
title = {Clines, clusters, and the effect of study design on the inference of human population structure},
abstract = {Previously, we observed that without using prior information about individual sampling locations, a clustering algorithm applied to multilocus genotypes from worldwide human populations produced genetic clusters largely coincident with major geographic regions. It has been argued, however, that the degree of clustering is diminished by use of samples with greater uniformity in geographic distribution, and that the clusters we identified were a consequence of uneven sampling along genetic clines. Expanding our earlier dataset from 377 to 993 markers, we systematically examine the influence of several study design variables--sample size, number of loci, number of clusters, assumptions about correlations in allele frequencies across populations, and the geographic dispersion of the sample--on the "clusteredness" of individuals. With all other variables held constant, geographic dispersion is seen to have comparatively little effect on the degree of clustering. Examination of the relationship between genetic and geographic distance supports a view in which the clusters arise not as an artifact of the sampling scheme, but from small discontinuous jumps in genetic distance for most population pairs on opposite sides of geographic barriers, in comparison with genetic distance for pairs on the same side. Thus, analysis of the 993-locus dataset corroborates our earlier results: if enough markers are used with a sufficiently large worldwide sample, individuals can be partitioned into genetic clusters that match major geographic subdivisions of the globe, with some individuals from intermediate geographic locations having mixed membership in the clusters that correspond to neighboring regions.},
affiliation = {Department of Human Genetics, Bioinformatics Program, and the Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. rnoah@umich.edu},
number = {6},
pages = {e70},
volume = {1},
year = {2005},
month = {Dec},
language = {eng},
keywords = {Genetics: Population, Cluster Analysis, Humans, Models: Genetic, Genotype, Genome: Human, Models: Statistical, Multigene Family, Gene Frequency, Population Groups, Alleles, Geography},
date-added = {2010-02-23 08:37:28 +0100},
date-modified = {2010-02-23 08:37:28 +0100},
doi = {10.1371/journal.pgen.0010070},
pmid = {16355252},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6506},
rating = {0}
}

@article{Cook:2008p415,
author = {RD Cook and L Forzani},
journal = {Biometrika},
title = {Covariance reducing models: An alternative to spectral modelling of covariance matrices},
abstract = {We introduce covariance reducing models for studying the sample covariance matrices of a random vector observed in different populations. The models are based on reducing the sample covariance matrices to an informational core that is sufficient to characterize the variance hetero- geneity among the populations. They possess useful equivariance properties and provide a clear alternative to spectral models for covariance matrices.},
affiliation = {School of Statistics, University of Minnesota, Minneapolis, Minnesota 55455, U.S.A.},
number = {4},
pages = {799--812},
volume = {95},
year = {2008},
keywords = {Grassmann manifolds, Envelopes, Central subspace, Dimension reduction, Reducing subspaces},
date-added = {2010-01-03 11:59:14 +0100},
date-modified = {2010-01-03 12:01:36 +0100},
doi = {10.1093/biomet/asn052},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Cook-2008-Biometrika_Covariance%20reducing.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p415},
rating = {0}
}

@article{Mortaud:2010p7656,
author = {Stephane Mortaud and Laurent Nicolas and Walter Pinoteau and Sylvie Tordjman and Mich{\`e}le Carlier and Pierre L Roubertoux},
journal = {Behav Genet},
title = {Brain pathways mediating the pro-aggressive effect of the steroid sulfatase (Sts) gene},
abstract = {STS is the single enzyme that converts all steroid sulfates into their free steroid forms. Initiation of attack behavior against conspecific male mice appeared to be linked to Sts. Here we have confirmed the role of Sts through an association study with attack behavior. Previous studies indicated a positive correlation between the initiation of attack behavior and liver STS concentration levels in male mice, but this finding was not compatible with established knowledge of STS mechanisms. High STS concentrations induce low concentrations of sulfated steroids. Sulfated and un-sulfated steroids are GABA(A) receptor agonists and NMDA receptor positive allosteric modulators. This synaptic pattern of functioning can generate attack behavior and we have confirmed here that an injection of the sulfated steroid dehydroepiandrosterone sulfate (DHEA-S) increases attack behavior. To solve the paradox, we measured the transcription activity of the genes underlying the pathways involved in the hydrolysis of sulfated steroids and leading to the formation of un-conjugated steroids in the mouse brain. We observed that the genes monitoring the steroid biosynthesis pathways exhibited a transcription pattern resulting in an increased sulfotransferase activity in the attacking males that could counterbalance the de-sulfating activity of Sts in the attacking mice.},
affiliation = {Universit{\'e} d'Orl{\'e}ans, Orl{\'e}ans, France.},
number = {2},
pages = {211--9},
volume = {40},
year = {2010},
month = {Mar},
language = {eng},
date-added = {2010-03-15 23:25:01 +0100},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-010-9340-6},
pmid = {20155394},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mortaud-2010-Behav%20Genet_Brain%20pathways%20media.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7656},
rating = {0}
}

@article{Caprara:2009p7646,
author = {Gian Vittorio Caprara and Corrado Fagnani and Guido Alessandri and Patrizia Steca and Antonella Gigantesco and Luigi Luca Cavalli Sforza and Luigi Luca Cavalli Sforza and Maria Antonietta Stazi},
journal = {Behav Genet},
title = {Human optimal functioning: the genetics of positive orientation towards self, life, and the future},
abstract = {Certain personality characteristics such as self-esteem, life satisfaction, and optimism are fundamental components of positive mental health status and well-being. There is consistent evidence that these traits tend to be substantially correlated in individuals. However, no previous studies have investigated the origin of such correlation. This research used the twin method to unravel the genetic and environmental architecture of self-esteem, life satisfaction, and optimism, along with their mutual interplay. The sample was derived from the population-based Italian Twin Register, and included 428 twin pairs, aged 23-24 years. Multivariate genetic modeling showed that genes influencing self-esteem, life satisfaction, and optimism are largely overlapping. Furthermore, results indicated that the environmental components of the traits may overlap only modestly, and suggested that a sizeable amount of variance in the traits may be explained by environmental effects specific to each of them.},
affiliation = {Psychology Department, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy. gianvittorio.caprara@uniroma1.it},
number = {3},
pages = {277--84},
volume = {39},
year = {2009},
month = {May},
language = {eng},
keywords = {Culture, Social Perception, Personality, Adaptation: Psychological, Models: Genetic, Male, Epistasis: Genetic, Registries, Risk Factors, Depressive Disorder, Diseases in Twins, Female, Young Adult, Italy, Motivation, Social Environment, Self Concept, Quality of Life, Temperament, Humans},
date-added = {2010-03-15 23:16:41 +0100},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-009-9267-y},
pmid = {19360463},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Caprara-2009-Behav%20Genet_Human%20optimal%20functi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7646},
rating = {0}
}

@article{Frisher:2007p7571,
author = {Martin Frisher and Heath Heatlie and Matthew Hickman},
journal = {BMC Public Health},
title = {Validating estimates of problematic drug use in England},
abstract = {BACKGROUND: UK Government expenditure on combatting drug abuse is based on estimates of illicit drug users, yet the validity of these estimates is unknown. This study aims to assess the face validity of problematic drug use (PDU) and injecting drug use (IDU) estimates for all English Drug Action Teams (DATs) in 2001. The estimates were derived from a statistical model using the Multiple Indicator Method (MIM). METHODS: Questionnaire study, in which the 149 English Drug Action Teams were asked to evaluate the MIM estimates for their DAT. RESULTS: The response rate was 60% and there were no indications of selection bias. Of responding DATs, 64% thought the PDU estimates were about right or did not dispute them, while 27% had estimates that were too low and 9% were too high. The figures for the IDU estimates were 52% (about right), 44% (too low) and 3% (too high). CONCLUSION: This is the first UK study to determine the validity estimates of problematic and injecting drug misuse. The results of this paper highlight the need to consider criterion and face validity when evaluating estimates of the number of drug users.},
affiliation = {Department of Medicines Management, School of Pharmacy, Keele University, ST5 5BG, UK. m.frisher@keele.ac.uk},
pages = {286},
volume = {7},
year = {2007},
month = {Jan},
language = {eng},
keywords = {Substance Abuse: Intravenous, Middle Aged, Probability, England, Male, Factor Analysis: Statistical, Prevalence, Vulnerable Populations, Female, Substance-Related Disorders, Adolescent, Adult, Regression Analysis, Confidence Intervals, Humans, Population Surveillance, Questionnaires},
date-added = {2010-03-14 10:59:59 +0100},
date-modified = {2010-03-14 11:00:03 +0100},
doi = {10.1186/1471-2458-7-286},
pii = {1471-2458-7-286},
pmid = {17927809},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Frisher-2007-BMC%20Public%20Health_Validating%20estimates.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7571},
rating = {2}
}

@techreport{Davidson:2006,
author = {R Davidson and J MacKinnon},
journal = {Techreport},
title = {Bootstrap Inference in a Linear Equation Estimated by Instrumental Variables},
affiliation = {Queen's Economics Department},
year = {2006},
date-added = {2010-01-10 11:33:18 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Davidson-2006-Techreport_Bootstrap%20Inference.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1987},
rating = {0}
}

@article{Berk:2010p4269,
author = {R A Berk and Jan de Leeuw},
title = {Multilevel statistical models and ecological scaling},
date-added = {2010-01-23 21:36:03 +0100},
date-modified = {2010-07-29 20:45:39 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Berk--_Multilevel%20statistic.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4269},
rating = {0}
}

@article{Fan:2005p10472,
author = {Jin Fan and Bruce D McCandliss and John Fossella and Jonathan I Flombaum and Michael I Posner},
journal = {Neuroimage},
title = {The activation of attentional networks},
abstract = {Alerting, orienting, and executive control are widely thought to be relatively independent aspects of attention that are linked to separable brain regions. However, neuroimaging studies have yet to examine evidence for the anatomical separability of these three aspects of attention in the same subjects performing the same task. The attention network test (ANT) examines the effects of cues and targets within a single reaction time task to provide a means of exploring the efficiency of the alerting, orienting, and executive control networks involved in attention. It also provides an opportunity to examine the brain activity of these three networks as they operate in a single integrated task. We used event-related functional magnetic resonance imaging (fMRI) to explore the brain areas involved in the three attention systems targeted by the ANT. The alerting contrast showed strong thalamic involvement and activation of anterior and posterior cortical sites. As expected, the orienting contrast activated parietal sites and frontal eye fields. The executive control network contrast showed activation of the anterior cingulate along with several other brain areas. With some exceptions, activation patterns of these three networks within this single task are consistent with previous fMRI studies that have been studied in separate tasks. Overall, the fMRI results suggest that the functional contrasts within this single task differentially activate three separable anatomical networks related to the components of attention.},
affiliation = {Laboratory of Neuroimaging, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA. Jin.Fan@mssm.edu},
number = {2},
pages = {471--9},
volume = {26},
year = {2005},
month = {Jun},
language = {eng},
keywords = {Orientation, Cues, Cerebral Cortex, Male, Neuropsychological Tests, Psychomotor Performance, Adolescent, Functional Laterality, Nerve Net, Temporal Lobe, Attention, Thalamus, Humans, Algorithms, Female, Magnetic Resonance Imaging, Parietal Lobe, Adult, Reaction Time},
date-added = {2010-04-07 11:06:20 +0200},
date-modified = {2010-04-07 11:06:20 +0200},
doi = {10.1016/j.neuroimage.2005.02.004},
pii = {S1053-8119(05)00098-4},
pmid = {15907304},
URL = {http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-4FRKVJ2-4&_user=2432700&_coverDate=06%252F30%252F2005&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000057263&_version=1&_urlVersion=0&_userid=2432700&md5=728fde9364808588f77d1a3031eb7c84},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fan-2005-Neuroimage_The%20activation%20of%20at.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10472},
rating = {0}
}

@article{Kusumi:2005p11594,
author = {Ichiro Kusumi and Takuya Masui and Chihiro Kakiuchi and Katsuji Suzuki and Tatsuyuki Akimoto and Ryota Hashimoto and Hiroshi Kunugi and Tadafumi Kato and Tsukasa Koyama},
journal = {Neurosci Lett},
title = {Relationship between XBP1 genotype and personality traits assessed by TCI and NEO-FFI},
abstract = {There have been several researches on the role of personality in the pathophysiology of bipolar disorder. Recently, a polymorphism of XBP1, a pivotal gene in the endoplasmic reticulum (ER) stress response, was shown to contribute to the genetic risk factor for bipolar disorder. Therefore, in this study, we examined the relationship between the XBP1 gene polymorphism and the personality traits assessed by two self-rating scales, a shortened version of Temperament and Character Inventory (TCI) and NEO-Five Factor Inventory (NEO-FFI) in healthy subjects. The present results suggested that the XBP1 gene polymorphism was associated with the NEO-FFI score of neuroticism in female subjects. However, no significant differences in the other personality scale scores of both assessments were observed among normal subjects with -116C/C, C/G and G/G genotypes. Further investigations are necessary to examine the relationship in patients with bipolar disorder, or use full version of various self-rating personality assessments.},
affiliation = {Department of Psychiatry, Hokkaido University Graduate School of Medicine, North 15, West 7, Sapporo, Hokkaido 060-8638, Japan. ikusumi@med.hokudai.ac.jp},
number = {1-2},
pages = {7--10},
volume = {391},
year = {2005},
month = {Dec},
language = {eng},
keywords = {Polymorphism: Genetic, Personality, Statistics as Topic, Personality Assessment, Transcription Factors, Risk Factors, Prevalence, Male, Genetic Predisposition to Disease, Adult, Humans, Japan, Questionnaires, Nuclear Proteins, Female, Bipolar Disorder, Quantitative Trait Loci, DNA-Binding Proteins, Genotype, Risk Assessment},
date-added = {2010-05-09 21:18:08 +0200},
date-modified = {2010-05-09 21:18:08 +0200},
doi = {10.1016/j.neulet.2005.08.023},
pii = {S0304-3940(05)00937-7},
pmid = {16154272},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Kusumi-2005-Neurosci%20Lett_Relationship%20between.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11594},
rating = {0}
}

@article{Yeh:2010p12573,
author = {Michelle T Yeh and Emil F Coccaro and Kristen C Jacobson},
journal = {Behav Genet},
title = {Multivariate Behavior Genetic Analyses of Aggressive Behavior Subtypes},
abstract = {This study examined the genetic and environmental architecture underlying aggressive behavior measured by the Life History of Aggression Questionnaire (LHA; Coccaro et al. 1997a). Following preliminary phenotypic factor analysis procedures, multivariate behavioral genetics models were fit to responses from 2,925 adult twins from the PennTwins cohort on five LHA items assessing lifetime frequency of temper tantrums, indirect aggression, verbal aggression, fighting, and physical assault. The best-fitting model was a 2-factor common pathway model, indicating that these five aggressive behaviors are underpinned by two distinct etiological factors with different genetic and nonshared environmental influences. Although there was evidence of significant sex differences, the structure of the two factors appeared to be quite similar in males and females, where General Aggression and Physical Aggression factors emerged. Heritability of these factors ranged from .37 to .57, and nonshared environmental effects ranged from .43 to .63. The results of this study highlight the heterogeneous nature of the aggression construct and the need to consider differences in genetic and environmental influences on individual aggressive behaviors in a multivariate context.},
affiliation = {Department of Psychiatry and Behavioral Neuroscience, University of Chicago, CNPRU, Chicago, IL, USA.},
pages = {},
year = {2010},
month = {Apr},
language = {ENG},
date-added = {2010-06-15 22:24:55 +0200},
date-modified = {2010-07-29 20:09:07 +0200},
doi = {10.1007/s10519-010-9363-z},
pmid = {20432061},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Yeh-2010-Behav%20Genet_Multivariate%20Behavio.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12573},
rating = {0}
}

@article{Hernandez:2006p5908,
author = {Ana Hern{\'a}ndez and Bego{\~n}a Espejo and Vicente Gonz{\'a}lez-Rom{\'a}},
journal = {Psicothema},
title = {The functioning of central categories Middle Level and Sometimes in graded response scales: does the label matter?},
abstract = {The present study evaluates the extent to which central categories explicitly labeled as being in the middle of the other response categories, specifically Middle Level and Sometimes, function as expected according to the integer scoring system. The assumptions are tested by means of Bock's Nominal Model in two 5-response scales. Results show that the assumption of the ordering of the response categories is met for all the items. The ordering of thresholds is satisfied for all but one item with the central category Middle Level . Results are compared with those obtained when middle categories are not explicitly labeled as being in the middle of the other response categories, as in the case of Not Sure , Undecided or?},
affiliation = {Facultad de Psicolog{\'\i}a, Universidad de Valencia, Spain. Ana.Hernandez@uv.es},
number = {2},
pages = {300--6},
volume = {18},
year = {2006},
month = {May},
language = {eng},
keywords = {Quality of Life, Choice Behavior, Models: Theoretical, Job Satisfaction, Research Design, Administrative Personnel, Male, Terminology as Topic, Public Health Administration, Public Health, Spain, Sampling Studies, Adult, Questionnaires, Humans, Work, Female},
date-added = {2010-02-18 23:09:50 +0100},
date-modified = {2010-07-29 19:45:05 +0200},
pmid = {17296048},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hern%C3%A1ndez-2006-Psicothema_The%20functioning%20of%20c.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5908},
rating = {0}
}

@article{Banerjee:1999p2659,
author = {M Banerjee and M Capozzoli and L McSweeney and D Sinha},
journal = {The Canadian Journal of Statistics},
title = {Beyond Kappa: A review of interrater agreement measures},
number = {1},
pages = {3--23},
volume = {27},
year = {1999},
date-added = {2010-01-12 22:46:20 +0100},
date-modified = {2010-01-12 22:47:51 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2659},
rating = {0}
}

@article{Shyn:2009p3964,
author = {S I Shyn and J Shi and J B Kraft and J B Potash and J A Knowles and M M Weissman and H A Garriock and J S Yokoyama and P J McGrath and E J Peters and W A Scheftner and W Coryell and W B Lawson and D Jancic and P V Gejman and A R Sanders and P Holmans and S L Slager and D F Levinson and S P Hamilton},
journal = {Mol Psychiatry},
title = {Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies},
abstract = {We report a genome-wide association study (

repository: sergiud/bibtex-spirit

repo_name: sergiud/bibtex-spirit

gha_license_id: MIT