text:
have sex when "high" on alcohol or drugs, to have a greater number of lifetime sex partners, and to abuse alcohol or drugs than were nondepressed patients. Associations of HIV risk behaviors with depression persisted after adjustment for substance abuse. CONCLUSIONS: Depression in STD clinic patients is associated with HIV risk behaviors but not STD diagnosis. Identifying depression and developing strategies to intervene effectively may reduce HIV risk behaviors and improve health outcomes.},
affiliation = {Department of Psychiatry, Johns Hopkins School of Medicine, 550 N. Broadway, Suite 203, Baltimore, MD 21205, USA. hhutton@jhmi.edu},
number = {5},
pages = {912--4},
volume = {161},
year = {2004},
month = {May},
language = {eng},
keywords = {Sexual Behavior, Substance-Related Disorders, Middle Aged, Ambulatory Care Facilities, Risk-Taking, Depressive Disorder, Prostitution, Prevalence, Adult, Female, Sexually Transmitted Diseases, Comorbidity, Baltimore, Humans, Adolescent, Cross-Sectional Studies, HIV Infections, Health Behavior, Male, Sexual Partners},
date-added = {2010-08-04 09:26:37 +0200},
date-modified = {2010-08-04 09:26:37 +0200},
pmid = {15121659},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hutton-2004-Am%20J%20Psychiatry_Depression%20and%20HIV%20r.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13999},
rating = {0}
}

@article{Talley:2010p13426,
author = {Amelia E Talley and B Ann Bettencourt},
journal = {AIDS Behav},
title = {A relationship-oriented model of HIV-related stigma derived from a review of the HIV-affected couples literature},
abstract = {Previous research has focused on the influence of HIV-related stigma for the psychological adjustment and physical health of persons with HIV/AIDS. Few studies, however, have examined the impact of HIV-related stigma on close relationships where one or both couple members have HIV/AIDS. The current review will integrate previous research findings to substantiate a relationship-oriented theoretical model of HIV-related stigma that delineates interpersonal variables important for understanding the influence of types of HIV-related stigma on couple-level as well as relevant individual-level outcomes. In doing so, supportive evidence is presented from the extant quantitative and qualitative literature that has assessed or examined HIV-affected couple members' experiences with HIV-related stigma. Implications from this review are presented for researchers who examine issues related to HIV-related stigma.},
affiliation = {University of Missouri, Columbia, MO, USA. aetyrd@mizzou.edu},
number = {1},
pages = {72--86},
volume = {14},
year = {2010},
month = {Feb},
language = {eng},
keywords = {Psychology, Humans, Social Support, Stereotyping, Male, Interpersonal Relations, Female, HIV Infections, Sexual Partners},
date-added = {2010-07-01 19:35:47 +0200},
date-modified = {2010-07-01 19:35:47 +0200},
doi = {10.1007/s10461-008-9493-y},
pmid = {19037718},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Talley-2010-AIDS%20Behav_A%20relationship-orien.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13426},
rating = {0}
}

@article{Keng:2010p12799,
author = {L Keng and T H Ho and T A Chen and B G Dodd},
title = {A Comparison of Item and Testlet Selection Procedures in Computerized Adaptive Testing},
abstract = {Testlet response theory (TRT) is a measurement model that can capture local dependency in testlet-based tests. One of the purported advantages of TRT over the more commonly-used polytomous IRT approach to modeling testlet-based tests is that it allows for ad hoc testlet construction in a testlet-based computer adaptive test (CAT). The goal of this study was to investigate the merits of such a CAT design. Specifically, it examined the use of testlet-based CATs that not only chose each testlet adaptively, but they also adaptively selected each item within the testlet, based on the estimated examinee proficiency. This design was termed a CAT with adaptive testlets, and it was compared against a CAT whose within-testlet items were all pre-determined and fixed (termed a CAT with fixed testlets). Real data from a large-scale assessment were calibrated using the 3PL-TRT model and used in this simulation study, which compared these testlet-based CAT designs on their measurement and exposure control properties. The study found that the use of adaptive testlets improved measurement precision while achieving better pool utilization rates. The use of an item-level exposure control procedure within a CAT with adaptive testlets resulted in similar measurement precision, but only a modest gain in pool utilization rates, when compared to a CAT with adaptive testlets and no item-level exposure control. This study represented an initial examination of the properties of CATs with adaptive testlets. As such, suggestions for future research are also provided.},
date-added = {2010-06-18 21:22:31 +0200},
date-modified = {2010-06-18 21:23:22 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Keng--_A%20Comparison%20of%20Item.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12799},
rating = {0}
}

@article{Albaum:1997p5889,
author = {G Albaum},
journal = {Journal of the Market Research Society},
title = {The Likert scale revisited: an alternate version (product preference testing)},
abstract = {An investigation of the effect of alternative scale formats on intensity of attitudes report based on the Likert scales of agreement was conducted. The study utilized both a one-stage format and a two-stage alternate format in three separate experiments on sample population of college students from three different nations. The two-stage format, which generated the greatest amount of extreme-position response, was determined to be a better gauge of product preferences.},
number = {i2},
pages = {331},
volume = {39},
year = {1997},
date-added = {2010-02-17 21:01:11 +0100},
date-modified = {2010-08-19 13:42:37 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Albaum-1997-Journal%20of%20the%20Market%20Research%20Society_The%20Likert%20scale%20rev.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5889},
read = {Yes},
rating = {3}
}

@article{Krueger:2008p9129,
author = {Robert F Krueger and Susan South and Wendy Johnson and William Iacono},
journal = {J Pers},
title = {The heritability of personality is not always 50%: gene-environment interactions and correlations between personality and parenting},
abstract = {Twin studies of personality are consistent in attributing approximately half of the variance in personality to genetic effects, with the remaining variance attributed to environments that make people within the same families different. Such conclusions, however, are based on quantitative models of human individual differences that estimate genetic and environmental contributions as constants for entire populations. Recent advances in statistical modeling allow for the possibility of estimating genetic and environmental contributions contingent on other variables, allowing the quantification of phenomena that have traditionally been characterized as gene-environment interaction and correlation. We applied these newer models to understand how adolescents' descriptions of their relationships with their parents might change or moderate the impact of genetic and environmental factors on personality. We documented notable moderation in the domains of positive and negative emotionality, with parental relationships acting both to enhance and diminish both genetic and environmental effects. We discuss how genetic and environmental contributions to personality might be more richly conceptualized as dynamic systems of gene-environment interplay--systems that are not captured by classical concepts, such as the overall heritability of personality.},
affiliation = {University of Minnesota-Twin Cities, USA. rkrueger@artsci.wustl.edu},
number = {6},
pages = {1485--522},
volume = {76},
year = {2008},
month = {Dec},
language = {eng},
keywords = {Humans, Phenotype, Young Adult, Social Environment, Personality, Male, Adolescent, Parent-Child Relations, Personality Inventory, Psychometrics, Twins, Parenting, Follow-Up Studies, Female, Minnesota, Adolescent Behavior},
date-added = {2010-03-22 13:26:17 +0100},
date-modified = {2010-07-29 19:35:22 +0200},
doi = {10.1111/j.1467-6494.2008.00529.x},
pii = {JOPY529},
pmid = {19012656},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Krueger-2008-J%20Pers_The%20heritability%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9129},
read = {Yes},
rating = {0}
}

@article{Emsley:2010p13695,
author = {Richard Emsley and Graham Dunn and Ian R White},
journal = {Stat Methods Med Res},
title = {Mediation and moderation of treatment effects in randomised controlled trials of complex interventions},
abstract = {Complex intervention trials should be able to answer both pragmatic and explanatory questions in order to test the theories motivating the intervention and help understand the underlying nature of the clinical problem being tested. Key to this is the estimation of direct effects of treatment and indirect effects acting through intermediate variables which are measured post-randomisation. Using psychological treatment trials as an example of complex interventions, we review statistical methods which crucially evaluate both direct and indirect effects in the presence of hidden confounding between mediator and outcome. We review the historical literature on mediation and moderation of treatment effects. We introduce two methods from within the existing causal inference literature, principal stratification and structural mean models, and demonstrate how these can be applied in a mediation context before discussing approaches and assumptions necessary for attaining identifiability of key parameters of the basic causal model. Assuming that there is modification by baseline covariates of the effect of treatment (i.e. randomisation) on the mediator (i.e. covariate by treatment interactions), but no direct effect on the outcome of these treatment by covariate interactions leads to the use of instrumental variable methods. We describe how moderation can occur through post-randomisation variables, and extend the principal stratification approach to multiple group methods with explanatory models nested within the principal strata. We illustrate the new methodology with motivating examples of randomised trials from the mental health literature.},
affiliation = {Health Methodology Research Group, School of Community Based Medicine, University of Manchester, UK.},
number = {3},
pages = {237--70},
volume = {19},
year = {2010},
month = {Jun},
language = {eng},
date-added = {2010-07-11 09:06:08 +0200},
date-modified = {2010-07-11 09:06:13 +0200},
doi = {10.1177/0962280209105014},
pii = {0962280209105014},
pmid = {19608601},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Emsley-2010-Stat%20Methods%20Med%20Res_Mediation%20and%20modera.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13695},
rating = {3}
}

@article{Prieto:2003,
author = {Luis Prieto and Jordi Alonso and Rosa Lamarca},
journal = {Health Qual Life Outcomes},
title = {Classical test theory versus Rasch analysis for quality of life questionnaire reduction},
number = {27},
volume = {1},
year = {2003},
date-added = {2010-01-10 11:33:23 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Prieto-2003-Health%20and%20Quality%20of%20Life%20Outcomes_Classical%20test%20theor.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2131},
rating = {0}
}

@article{Wang:2009p6613,
author = {C Y Wang and Ziding Feng},
journal = {Biostatistics},
title = {Boosting with missing predictors},
abstract = {Boosting is an important tool in classification methodology. It combines the performance of many weak classifiers to produce a powerful committee, and its validity can be explained by additive modeling and maximum likelihood. The method has very general applications, especially for high-dimensional predictors. For example, it can be applied to distinguish cancer samples from healthy control samples by using antibody microarray data. Microarray data are often high-dimensional and many of them are incomplete. One natural idea is to impute a missing variable based on the observed predictors. However, the calculation of imputation for high-dimensional predictors with missing data may be rather tedious. In this paper, we propose 2 conditional mean imputation methods. They can be applied to the situation even when a complete-case subset does not exist. Simulation results indicate that the proposed methods are superior than other naive methods. We apply the methods to a pancreatic cancer study in which serum protein microarrays are used for classification.},
affiliation = {Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M2-B500, PO Box 19024, Seattle, WA 98109-1024, USA. cywang@fhcrc.org.},
pages = {},
year = {2009},
month = {Nov},
language = {ENG},
date-added = {2010-03-03 20:23:01 +0100},
date-modified = {2010-03-03 20:23:01 +0100},
doi = {10.1093/biostatistics/kxp052},
pii = {kxp052},
pmid = {19948743},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wang-2009-Biostatistics_Boosting%20with%20missin.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6613},
rating = {0}
}

@article{dUva:2008p423,
author = {Teresa Bago d'Uva and Owen O'Donnell and Eddy van Doorslaer},
journal = {Int J Epidemiol},
title = {Differential health reporting by education level and its impact on the measurement of health inequalities among older Europeans},
abstract = {BACKGROUND: This study aims to establish whether health reporting differs by education level and, if so, to determine the extent to which this biases the measurement of health inequalities among older Europeans. METHODS: Data are from the Survey of Health, Ageing and Retirement in Europe (SHARE) covering eight countries. Differential reporting of health by education is identified from ratings of anchoring vignettes that describe fixed health states. Ratings of own health in six domains (mobility, pain, sleep, breathing, emotional health and cognition) are corrected for differences in reporting using an extended ordered probit model. For each country and health domain, we compare the corrected with the uncorrected age-sex standardized high-to-low education rate ratio for the absence of a health problem. RESULTS: Before correction for reporting differences across the 48 combinations of country by health domain, there was no inequality in health by education (P > 0.05) in 32 of 48 cases. However, there were reporting differences by education (P < 0.05) in 29 out of 48 cases. In general, higher educated older Europeans are more likely to rate a given health state negatively (except for Spain and Sweden). Correcting for these differences generally increases health inequalities (except for Spain and Sweden) and results in the emergence of inequalities in 18 cases (P < 0.05), which may be considered 'statistically significant'. The greatest impact is in Belgium, Germany and The Netherlands, where inequalities (P < 0.05) appear only after adjustment in four of the six health domains. CONCLUSIONS: These results emphasize the need to account for differences in the reporting of health. Measured health inequalities by education are often underestimated, and even go undetected, if no account is taken of these reporting differences.},
affiliation = {Department of Applied Economics, Erasmus School of Economics, Erasmus University, Rotterdam, The Netherlands. bagoduva@few.eur.nl},
number = {6},
pages = {1375--83},
volume = {37},
year = {2008},
month = {Dec},
language = {eng},
keywords = {Male, Health Status Disparities, Humans, Educational Status, Health Surveys, Female, Likelihood Functions, Aged, Europe, Bias (Epidemiology), Middle Aged, Health Status},
date-added = {2010-01-03 12:20:56 +0100},
date-modified = {2010-01-03 12:20:56 +0100},
doi = {10.1093/ije/dyn146},
pii = {dyn146},
pmid = {18676985},
local-url = {file://localhost/Users/chl/Dropbox/Papers/d'Uva-2008-Int%20J%20Epidemiol_Differential%20health.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p423},
read = {Yes},
rating = {0}
}

@article{ThorntonWells:2004p2930,
author = {Tricia A Thornton-Wells and Jason H Moore and Jonathan L Haines},
journal = {Trends Genet},
title = {Genetics, statistics and human disease: analytical retooling for complexity},
abstract = {Molecular biologists and geneticists alike now acknowledge that most common human diseases with a genetic component are likely to have complex etiologies. Yet despite this belief, many statistical geneticists continue applying, in slightly new and different ways, methodologies that were developed to dissect much simpler etiologies. In this article, we characterize, with examples, the various factors that can complicate genetic analysis and demonstrate their shared features and how they affect genetic analysis. We describe a variety of approaches that are currently available, revealing methodological gaps and suggesting new directions for method development. Finally, we propose a comprehensive two-step approach to analysis that systemically addresses the different genetic factors that are likely to underlie complex diseases.},
affiliation = {Neuroscience Graduate Program, Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, TN 37240, USA.},
number = {12},
pages = {640--7},
volume = {20},
year = {2004},
month = {Dec},
language = {eng},
keywords = {Models: Genetic, Models: Statistical, Genetic Diseases: Inborn, Polymorphism: Single Nucleotide, Quantitative Trait Loci, Humans, Genetic Heterogeneity, Genetics: Medical, Phenotype},
date-added = {2010-01-13 22:17:44 +0100},
date-modified = {2010-01-13 22:17:44 +0100},
doi = {10.1016/j.tig.2004.09.007},
pii = {S0168-9525(04)00274-4},
pmid = {15522460},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Thornton-Wells-2004-Trends%20Genet_Genetics%20statistics.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2930},
rating = {0}
}

@article{Killeen:2006p7079,
author = {Peter R Killeen},
journal = {Psychon Bull Rev},
title = {Beyond statistical inference: a decision theory for science},
abstract = {Traditional null hypothesis significance testing does not yield the probability of the null or its alternative and, therefore, cannot logically ground scientific decisions. The decision theory proposed here calculates the expected utility of an effect on the basis of (1) the probability of replicating it and (2) a utility function on its size. It takes significance tests--which place all value on the replicability of an effect and none on its magnitude--as a special case, one in which the cost of a false positive is revealed to be an order of magnitude greater than the value of a true positive. More realistic utility functions credit both replicability and effect size, integrating them for a single index of merit. The analysis incorporates opportunity cost and is consistent with alternate measures of effect size, such as r2 and information transmission, and with Bayesian model selection criteria. An alternate formulation is functionally equivalent to the formal theory, transparent, and easy to compute.},
affiliation = {Department of Psychology, Arizona State University, Box 1104, Tempe, AZ 85287-1104, USA. killeen@asu.edu},
number = {4},
pages = {549--62},
volume = {13},
year = {2006},
month = {Aug},
language = {eng},
keywords = {Humans, Science, Data Interpretation: Statistical, Decision Making, Models: Statistical},
date-added = {2010-03-06 20:29:38 +0100},
date-modified = {2010-07-29 19:47:36 +0200},
pmid = {17201351},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Killeen-2006-Psychon%20Bull%20Rev_Beyond%20statistical%20i.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7079},
rating = {4}
}

@article{Zubairi:2006,
author = {A M Zubairi and N L A Kassim},
journal = {Malaysian Journal of ELT Research},
title = {Classical And Rasch Analyses Of Dichotomously Scored Reading Comprehension Test Items},
volume = {2},
year = {2006},
date-added = {2010-01-10 11:33:19 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Zubairi-2006-Malaysian%20Journal%20of%20ELT%20Research_Classical%20And%20Rasch.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2033},
rating = {0}
}

@article{Stewart:2000p11650,
author = {A L Stewart and A N{\'a}poles-Springer},
journal = {Med Care},
title = {Health-related quality-of-life assessments in diverse population groups in the United States},
abstract = {BACKGROUND: Effectiveness research needs to represent the increasing diversity of the United States. Health-related quality-of-life (HRQOL) measures are often included as secondary treatment outcomes. Because most HRQOL measures were developed in nonminority, well-educated samples, we must determine whether such measures are conceptually and psychometrically equivalent in diverse subgroups. Without equivalence, overall findings and observed group differences may contain measurement bias. OBJECTIVES: The objectives of this work were to discuss the nature of diversity, importance of ensuring the adequacy of HRQOL measures in diverse groups, methods for assessing comparability of HRQOL measures across groups, and methodological and analytical challenges. RESULTS: Integration of qualitative and quantitative methods is needed to achieve measurement adequacy in diverse groups. Little research explores conceptual equivalence across US subgroups; of the few studies of psychometric comparability, findings are inconsistent. Evidence is needed regarding whether current measures are comparable or need modifications to meet universality assumptions, and we need to determine the best methods for evaluating this. We recommend coordinated efforts to develop guidelines for assessing measurement adequacy across diverse subgroups, allocate resources for measurement studies in diverse populations, improve reporting of and access to measurement results by subgroups, and develop strategies for optimizing the universality of HRQOL measures and resolving inadequacies. CONCLUSIONS: We advocate culturally sensitive research that involves cultural subgroups throughout the research process. Because examining the cultural equivalence of HRQOL measures within the United States is somewhat new, we have a unique opportunity to shape the direction of this work through development and dissemination of appropriate methods.},
affiliation = {University of California San Francisco, Institute for Health and Aging, 94143-0646, USA. anitast@itsa.ucsf.edu},
number = {9 Suppl},
pages = {II102--24},
volume = {38},
year = {2000},
month = {Sep},
language = {eng},
keywords = {Research Design, Psychometrics, Awareness, Outcome Assessment (Health Care), Ethnic Groups, Cultural Diversity, Humans, Health Status Indicators, Cross-Cultural Comparison, United States, Quality of Life, Self Assessment (Psychology), Treatment Outcome, Questionnaires},
date-added = {2010-05-11 22:49:05 +0200},
date-modified = {2010-07-29 19:39:29 +0200},
pmid = {10982096},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11650},
rating = {0}
}

@article{Williams:1991p12809,
author = {S M Williams},
journal = {Neuropsychology},
title = {Handedness Inventories: Edinburgh Versus Annett},
abstract = {Two handedness inventories were compared. The Edin- burgh Handedness Inventory yielded more either-hand and fewer left-hand responses than does the Annett questionnaire. Both ques- tionnaires showed high internal consistency. Ear preference in tele- phone usage seemed to be related more to bimanual coordination than to hemispheric asymmetry for speech. No sex difference was found in the incidence of left-handedness.},
number = {1},
pages = {43--48},
volume = {5},
year = {1991},
date-added = {2010-06-21 19:56:14 +0200},
date-modified = {2010-06-21 19:56:59 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Williams-1991-Neuropsychology_Handedness%20Inventori.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12809},
rating = {0}
}

@article{Bernhard:1998p5993,
author = {J Bernhard and D F Cella and A S Coates and L Fallowfield and P A Ganz and C M Moinpour and P Mosconi and D Osoba and J Simes and C H{\"u}rny},
journal = {Stat Med},
title = {Missing quality of life data in cancer clinical trials: serious problems and challenges},
abstract = {Measurement of quality of life (QOL) in cancer clinical trials has increased in recent years as more groups realize the importance of such endpoints. A key problem has been missing data. Some QOL data may unavoidably be missing, as for example when patients are too ill to complete forms. Other important sources are potentially avoidable and can broadly be divided into three categories: (i) methodological factors; (ii) logistic and administrative factors; (iii) patient-related factors. Logistic and administrative factors, for example, staff oversights, have proven to be most important. Since most QOL measurements require patient self-report, it is usually not possible to rectify the failure to collect baseline data or any follow-up assessments. There is strong evidence that such data are not 'missing at random', and cannot be ignored without introducing bias. Although several approaches to the analysis of partly missing data have been described, none is entirely satisfactory. Prevention of avoidable missing data is better than attempted cure. In July 1996, an international conference on missing QOL data in cancer clinical trials reported the experience of most major groups involved. This paper will serve as an introduction to the problem and provide an estimation of its magnitude, and approaches to its prevention and solution.},
affiliation = {SIAK Coordinating Center, Bern, Switzerland. jbernhard@sakk.ch},
number = {5-7},
pages = {517--32},
volume = {17},
year = {1998},
month = {Jan},
language = {eng},
keywords = {Humans, Bias (Epidemiology), Quality of Life, Neoplasms, Research Design, Clinical Trials as Topic, Data Collection},
date-added = {2010-02-18 23:31:43 +0100},
date-modified = {2010-02-18 23:31:44 +0100},
pii = {10.1002/(SICI)1097-0258(19980315/15)17:5/7<517::AID-SIM799>3.0.CO;2-S},
pmid = {9549801},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bernhard-1998-Stat%20Med_Missing%20quality%20of%20l.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5993},
rating = {0}
}

@article{Furlanello2003,
author = {C Furlanello and M Serafini and S Merler and G Jurman},
journal = {Neural Netw},
title = {An accelerated procedure for recursive feature ranking on microarray data},
pages = {641--648},
volume = {16},
year = {2003},
date-added = {2010-01-12 14:26:51 +0100},
date-modified = {2010-07-29 19:41:07 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2509},
rating = {0}
}

@article{Rand:2010p14047,
author = {Debbie Rand and Janice J Eng and Pei-Fang Tang and Chihya Hung and Jiann-Shing Jeng},
journal = {Health Qual Life Outcomes},
title = {Daily physical activity and its contribution to the health-related quality of life of ambulatory individuals with chronic stroke},
abstract = {ABSTRACT: BACKGROUND: Participation in daily physical activity (PA) post-stroke has not previously been investigated as a possible explanatory variable of health-related quality of life (HRQL). The aims were 1) to determine the contribution of daily PA to the HRQL of individuals with chronic stroke and 2) to assess the relationship between the functional ability of these individuals to the amount of daily PA. METHODS: The amount of daily PA of forty adults with chronic stroke (mean age 66.5+/-9.6 years) was monitored using two measures. Accelerometers (Actical) were worn on the hip for three consecutive days in conjunction with a self-report questionnaire [the Physical Activity Scale for Individuals with Physical Disabilities (PASIPD)]. The daily physical activity was measured as the mean total accelerometer activity counts/day and the PASIPD scores as the metabolic equivalent (MET) hr/day. HRQL was assessed by the Physical and Mental composite scores of the Medical Outcomes Study Short-Form 36 (SF-36) in addition to the functional ability of the participants. Correlation and regression analyses were performed. RESULTS: After controlling for the severity of the motor impairment, the amount of daily PA, as assessed by the PASIPD and accelerometers, was found to independently contribute to 10-12% of the variance of the Physical Composite Score of the SF-36. No significant relationship was found between PA and the Mental Composite Score of the SF-36. The functional ability of the participants was found to be correlated to the amount of daily PA (r= 0.33- 0.67, p<0.01). CONCLUSION: The results suggest that daily PA is associated with better HRQL (as assessed by the Physical composite score of the SF-36) for people living with stroke. Daily PA should be encouraged to potentially increase HRQL. Accelerometers in conjunction with a self-report questionnaire may provide important measures of PA which can be monitored and modified, and potentially influence HRQL.},
number = {1},
pages = {80},
volume = {8},
year = {2010},
month = {Aug},
language = {ENG},
date-added = {2010-08-10 12:44:12 +0200},
date-modified = {2010-08-10 12:44:12 +0200},
doi = {10.1186/1477-7525-8-80},
pii = {1477-7525-8-80},
pmid = {20682071},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rand-2010-Health%20Qual%20Life%20Outcomes_Daily%20physical%20activ.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14047},
rating = {0}
}

@article{Ayers:2008p2426,
author = {E Ayers and B Junker},
journal = {Educational and Psychological Measurement},
title = {IRT Modeling of Tutor Performance To Predict End-of-year Exam Scores},
abstract = {Interest in end-of-year accountability exams has increased dramatically since the passing of the NCLB law in 2001. With this increased interest comes a desire to use student data collected throughout the year to estimate student proficiency and predict how well they will perform on end-of-year exams. In this paper we use student performance on the Assistment System, an on-line mathematics tutor, to show that replacing percent correct with an Item Response Theory (IRT) estimate of student proficiency leads to better fitting prediction models. In addition, other tutor performance metrics are used to further increase prediction accuracy. Finally we calculate prediction error bounds to attain an absolute measure to which our models can be compared.},
number = {6},
pages = {972--987},
volume = {68},
year = {2008},
keywords = {item response theory, Bayesian inference, intelligent tutoring systems, reliability, Cognitive modeling},
date-added = {2010-01-11 23:27:10 +0100},
date-modified = {2010-01-11 23:29:20 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ayers-2008-Educational%20and%20Psychological%20Measurement_IRT%20Modeling%20of%20Tuto.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2426},
rating = {0}
}

@article{Gosso:2006p10474,
author = {M F Gosso and M van Belzen and E J C de Geus and J C Polderman and P Heutink and Dorret I Boomsma and D Posthuma},
journal = {Genes Brain Behav},
title = {Association between the CHRM2 gene and intelligence in a sample of 304 Dutch families},
abstract = {The CHRM2 gene is thought to be involved in neuronal excitability, synaptic plasticity and feedback regulation of acetylcholine release and has previously been implicated in higher cognitive processing. In a sample of 667 individuals from 304 families, we genotyped three single-nucleotide polymorphisms (SNPs) in the CHRM2 gene on 7q31-35. From all individuals, standardized intelligence measures were available. Using a test of within-family association, which controls for the possible effects of population stratification, a highly significant association was found between the CHRM2 gene and intelligence. The strongest association was between rs324650 and performance IQ (PIQ), where the T allele was associated with an increase of 4.6 PIQ points. In parallel with a large family-based association, we observed an attenuated - although still significant - population-based association, illustrating that population stratification may decrease our chances of detecting allele-trait associations. Such a mechanism has been predicted earlier, and this article is one of the first to empirically show that family-based association methods are not only needed to guard against false positives, but are also invaluable in guarding against false negatives.},
affiliation = {Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands. mf.gosso@vumc.nl},
number = {8},
pages = {577--84},
volume = {5},
year = {2006},
month = {Nov},
language = {eng},
keywords = {Polymorphism: Single Nucleotide, Middle Aged, Twins: Monozygotic, Pedigree, Child, Receptor: Muscarinic M2, Male, Chromosomes: Human: Pair 7, Adolescent, Intelligence, Humans, Genetic Variation, Genetics: Population, Female, Adult, Netherlands, Twins: Dizygotic},
date-added = {2010-04-07 11:08:24 +0200},
date-modified = {2010-07-29 20:25:51 +0200},
doi = {10.1111/j.1601-183X.2006.00211.x},
pii = {GBB211},
pmid = {17081262},
URL = {http://www3.interscience.wiley.com/journal/118618277/abstract},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gosso-2006-Genes%20Brain%20Behav_Association%20between.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10474},
rating = {0}
}

@article{Meulman:2010p4021,
author = {J J Meulman},
title = {Optimal scaling methods for multivariate categorical data analysis},
date-added = {2010-01-18 15:44:45 +0100},
date-modified = {2010-01-18 15:45:27 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Meulman--_Optimal%20scaling%20meth.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4021},
rating = {0}
}

@article{Berge:2009p5486,
author = {Jerica M Berge and Melanie Wall and Katherine W Bauer and Dianne Neumark-Sztainer},
journal = {Obesity (Silver Spring)},
title = {Parenting Characteristics in the Home Environment and Adolescent Overweight: A Latent Class Analysis},
abstract = {Parenting style and parental support and modeling of physical activity and healthy dietary intake have been linked to youth weight status, although findings have been inconsistent across studies. Furthermore, little is known about how these factors co-occur, and the influence of the coexistence of these factors on adolescents' weight. This article examines the relationship between the co-occurrence of various parenting characteristics and adolescents' weight status. Data are from Project EAT (eating among teens), a population-based study of 4,746 diverse adolescents. Theoretical and latent class groupings of parenting styles and parenting practices were created. Regression analyses examined the relationship between the created variables and adolescents' BMI. Having an authoritarian mother was associated with higher BMI in sons. The co-occurrence of an authoritarian mother and neglectful father was associated with higher BMI for sons. Daughters' whose fathers did not model or encourage healthy behaviors reported higher BMIs. The co-occurrence of neither parent modeling healthy behaviors was associated with higher BMIs for sons, and incongruent parental modeling and encouraging of healthy behaviors was associated with higher BMIs in daughters. Although, further research into the complex dynamics of the home environment is needed, findings indicate that authoritarian parenting style is associated with higher adolescent weight status and incongruent parenting styles and practices between mothers and fathers are associated with higher adolescent weight status.},
affiliation = {Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, USA.},
pages = {},
year = {2009},
month = {Oct},
language = {ENG},
date-added = {2010-02-12 14:43:35 +0100},
date-modified = {2010-02-12 14:43:35 +0100},
doi = {10.1038/oby.2009.324},
pii = {oby2009324},
pmid = {19816417},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5486},
rating = {0}
}

@article{Brookes1999,
author = {A J Brookes},
journal = {Gene},
title = {The essense of SNPs},
pages = {177--186},
volume = {234},
year = {1999},
date-added = {2010-01-12 14:26:46 +0100},
date-modified = {2010-01-12 14:26:52 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2550},
rating = {0}
}

@article{Goldsmith:2010p10903,
author = {J Goldsmith},
title = {Probability for linguists},
abstract = {This paper offers a gentle introduction to probability for linguists, as- suming little or no background beyond what one learns in high school. The most important points that we emphasize are: the conceptual difference between probability and frequency, the use of maximizing probability of an observation by considering different models, and Kullback-Leibler divergence.
Nous offrons une introduction  ́el ́ementaire `a la th ́eorie des probabilit ́es pour les linguistes. En tirant nos exemples de domaines linguistiques, nous essayons de mettre en valeur l'utilit ́e de comprendre la diff ́erence entre les probabilit ́es et les fr ́equences, l' ́evaluation des analyses linguistiques par la calculation de la probabilit ́e quelles assignent aux donn ́ees observ ́ees, et la divergence Kullback-Leibler.},
date-added = {2010-04-11 13:49:20 +0200},
date-modified = {2010-04-11 13:50:05 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Goldsmith--_Probability%20for%20ling.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10903},
rating = {4}
}

@article{Walsh:2004p3612,
author = {B Walsh},
title = {Markov Chain Monte Carlo and Gibbs Sampling},
year = {2004},
date-added = {2010-01-16 18:29:39 +0100},
date-modified = {2010-01-16 18:30:06 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Walsh-2004-_Markov%20Chain%20Monte%20C.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3612},
rating = {0}
}

@article{Gladis:1999p5422,
author = {M M Gladis and E A Gosch and N M Dishuk and P Crits-Christoph},
journal = {Journal of Consulting and Clinical Psychology},
title = {Quality of life: expanding the scope of clinical significance},
abstract = {Clinical researchers have turned their attention to quality of life assessment as a means of broadening the evaluation of treatment outcomes. This article examines conceptual and methodological issues related to the use of quality of life measures in mental health. These include the lack of a good operational definition of the construct, the use of subjective versus objective quality of life indicators, and the nature of the relationship between symptoms and quality of life judgments. Of special concern is the ability of quality of life measures to detect treatment-related changes. The authors review the application of quality of life assessment across diverse patient groups and therapies and provide recommendations for developing comprehensive, psychometrically sophisticated quality of life measures.},
affiliation = {Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA. gladisl@landru.cpr.upenn.edu},
number = {3},
pages = {320--31},
volume = {67},
year = {1999},
month = {Jun},
language = {eng},
keywords = {Outcome Assessment (Health Care), Humans, Psychotherapy, Psychometrics, Quality of Life},
date-added = {2010-02-11 10:38:03 +0100},
date-modified = {2010-02-11 10:38:03 +0100},
pmid = {10369052},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5422},
rating = {0}
}

@article{Olweus:1997,
author = {D Olweus},
journal = {European Journal of Psychology of Education},
title = {Bully/Victim problems within school; facts and intervention},
abstract = {Les probl{\`e}mes de brutalit{\'e} entre enfants et jeunes {\`a} l'{\'e}cole sont particuli{\`e}rement pr{\'e}occupants dans les pays Scandinaves et, de plus en plus, dans d'autres pays {\'e}galement. Des larges enqu{\^e}tes r{\'e}alis{\'e}es par l'auteur, il ressort que du premier au neuvi{\`e}me grade, pr{\`e}s de 9% des {\'e}l{\`e}ves sont tr{\`e}s r{\'e}guli{\`e}rement victimes de brutalit{\'e}s et que 6-7% des {\'e}l{\`e}ves en agressent d' autres r{\'e}guli{\`e}rement. En d{\'e}mocratie, c'est un droit fondamental des enfants que d'{\^e}tre prot{\'e}g{\'e}s contre l'oppression et les humiliations r{\'e}p{\'e}t{\'e}es impliqu{\'e}es par ces pratiques. L'auteur a mis au point un programme d'intervention scolaire contre les brutalit{\'e}s, dont les effets ont {\'e}t{\'e} {\'e}valu{\'e}s dans 42 {\'e}coles pendant deux ans. Les r{\'e}sultats montrent que la fr{\'e}quence des probl{\`e}mes de violence a diminu{\'e} de 50-70%. En outre, l'importance des comportements antisociaux en g{\'e}n{\'e}ral, tels que le vandalisme, le vol, l'alcoolisme et les absences non autoris{\'e}es, a notablement diminu{\'e}. Les principaux contenus du programme et ses principes-cl{\'e}s sont pr{\'e}sent{\'e}s. L'objectif primordial du programme peut {\^e}tre d{\'e}crit comme une restructuration de l'environnement social. Le programme met l'accent sur les comportements et les attitudes caract{\'e}ris{\'e}s par l'association d'engagements positifs des enseignants et des parents, des limites strictes aux comportements inacceptables (nous n'acceptons pas la brutalit{\'e} dans notre classe/{\'e}cole), et l'utilisation coh{\'e}rente de sanctions elles-m{\^e}mes non brutales en cas de violation des r{\`e}gles. Les r{\'e}sultats positifs obtenus sont mis sur le compte de changements structuraux relatifs aux occasions et aux b{\'e}n{\'e}fices des comportements de brutalit{\'e}.},
pages = {495--510},
volume = {12},
year = {1997},
date-added = {2010-01-03 19:36:09 +0100},
date-modified = {2010-07-29 19:26:41 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1045},
rating = {0}
}

@article{Kendler:2007p2901,
author = {Kenneth S Kendler and John Myers and Carol A Prescott},
journal = {Arch Gen Psychiatry},
title = {Specificity of genetic and environmental risk factors for symptoms of cannabis, cocaine, alcohol, caffeine, and nicotine dependence},
abstract = {CONTEXT: Although genetic risk factors have been found to contribute to dependence on both licit and illicit psychoactive substances, we know little of how these risk factors interrelate. OBJECTIVE: To clarify the structure of genetic and environmental risk factors for symptoms of dependence on cannabis, cocaine, alcohol, caffeine, and nicotine in males and females. DESIGN: Lifetime history by structured clinical interview. SETTING: General community. PARTICIPANTS: Four thousand eight hundred sixty-five members of male-male and female-female pairs from the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. Main Outcome Measure Lifetime symptoms of abuse of and dependence on cannabis, cocaine, alcohol, caffeine, and nicotine. RESULTS: Controlling for greater symptom prevalence in males, genetic and environmental parameters could be equated across sexes. Two models explained the data well. The best-fit exploratory model contained 2 genetic factors and 1 individual environmental factor contributing to all substances. The first genetic factor loaded strongly on cocaine and cannabis dependence; the second, on alcohol and nicotine dependence. Nicotine and caffeine had high substance-specific genetic effects. A confirmatory model, which also fit well, contained 1 illicit drug genetic factor--loading only on cannabis and cocaine--and 1 licit drug genetic factor loading on alcohol, caffeine, and nicotine. However, these factors were highly intercorrelated (r = + 0.82). Large substance-specific genetic effects remained for nicotine and caffeine. CONCLUSIONS: The pattern of genetic and environmental risk factors for psychoactive substance dependence was similar in males and females. Genetic risk factors for dependence on common psychoactive substances cannot be explained by a single factor. Rather, 2 genetic factors-one predisposing largely to illicit drug dependence, the other primarily to licit drug dependence-are needed. Furthermore, a large proportion of the genetic influences on nicotine and particularly caffeine dependence appear to be specific to those substances.},
affiliation = {Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Medical School, Richmond, VA 23298-0126, USA. kendler@vcu.edu},
number = {11},
pages = {1313--20},
volume = {64},
year = {2007},
month = {Nov},
language = {eng},
keywords = {Sex Factors, Female, Substance-Related Disorders, Virginia, Adult, Environment, Genetic Predisposition to Disease, Cross-Sectional Studies, Male, Humans, Risk Factors},
date-added = {2010-01-13 15:00:39 +0100},
date-modified = {2010-01-13 15:00:39 +0100},
doi = {10.1001/archpsyc.64.11.1313},
pii = {64/11/1313},
pmid = {17984400},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2901},
rating = {0}
}

@article{Allen:2003p8759,
author = {P Finbarr Allen},
journal = {Health Qual Life Outcomes},
title = {Assessment of oral health related quality of life},
abstract = {In Dentistry, as in other branches of Medicine, it has been recognised that objective measures of disease provide little insight into the impact of oral disorders on daily living and quality of life. A significant body of development work has been undertaken to provide health status measures for use as outcome measures in dentistry. In descriptive population studies, poor oral health related quality of life is associated with tooth loss. There is a less extensive literature of longitudinal clinical trials, and measurement of change and interpretation of change scores continues to pose a challenge. This paper reviews the literature regarding the development and use of these oral health related QoL measures and includes an appraisal of future research needs in this area.},
affiliation = {Department of Restorative Dentistry, University Dental School {\&} Hospital, Wilton, Cork, Ireland. f.allen@ucc.ie},
pages = {40},
volume = {1},
year = {2003},
month = {Jan},
language = {eng},
keywords = {Quality Indicators: Health Care, Quality of Life, Health Status, Oral Health, Outcome Assessment (Health Care), Health Services Research, Humans, Questionnaires},
date-added = {2010-03-22 12:06:04 +0100},
date-modified = {2010-03-22 12:06:04 +0100},
doi = {10.1186/1477-7525-1-40},
pii = {1477-7525-1-40},
pmid = {14514355},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Allen-2003-Health%20and%20Quality%20of%20Life%20Outcomes_Assessment%20of%20oral%20h.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8759},
rating = {0}
}

@article{Sellke:2001p7070,
author = {T Sellke and M J Bayarri and J O Berger},
journal = {The American Statistician},
title = {Calibration of p Values for Testing Precise Null Hypotheses},
number = {1},
pages = {62--71},
volume = {55},
year = {2001},
date-added = {2010-03-06 20:12:52 +0100},
date-modified = {2010-07-29 19:51:39 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sellke-2001-The%20American%20Statistician_Calibration%20of%20p%20Val.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7070},
rating = {3}
}

@article{Pocock:1987p3998,
author = {S J Pocock and M D Hughes and R J Lee},
journal = {N Engl J Med},
title = {Statistical problems in the reporting of clinical trials. A survey of three medical journals},
abstract = {Reports of clinical trials often contain a wealth of data comparing treatments. This can lead to problems in interpretation, particularly when significance testing is used extensively. We examined 45 reports of comparative trials published in the British Medical Journal, the Lancet, or the New England Journal of Medicine to illustrate these statistical problems. The issues we considered included the analysis of multiple end points, the analysis of repeated measurements over time, subgroup analyses, trials of multiple treatments, and the overall number of significance tests in a trial report. Interpretation of large amounts of data is complicated by the common failure to specify in advance the intended size of a trial or statistical stopping rules for interim analyses. In addition, summaries or abstracts of trials tend to emphasize the more statistically significant end points. Overall, the reporting of clinical trials appears to be biased toward an exaggeration of treatment differences. Trials should have a clearer predefined policy for data analysis and reporting. In particular, a limited number of primary treatment comparisons should be specified in advance. The overuse of arbitrary significance levels (for example, P less than 0.05) is detrimental to good scientific reporting, and more emphasis should be given to the magnitude of treatment differences and to estimation methods such as confidence intervals.},
number = {7},
pages = {426--32},
volume = {317},
year = {1987},
month = {Aug},
language = {eng},
keywords = {Research Design, Clinical Trials as Topic, Statistics as Topic, Periodicals as Topic},
date-added = {2010-01-17 23:24:42 +0100},
date-modified = {2010-07-29 19:53:14 +0200},
pmid = {3614286},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3998},
rating = {0}
}

@article{Illig:2010p4889,
author = {Thomas Illig and Christian Gieger and Guangju Zhai and Werner R{\"o}misch-Margl and Rui Wang-Sattler and Cornelia Prehn and Elisabeth Altmaier and Gabi Kastenm{\"u}ller and Bernet S Kato and Hans-Werner Mewes and Thomas Meitinger and Martin Hrab{\'e} de Angelis and Florian Kronenberg and Nicole Soranzo and H-Erich Wichmann and Tim D Spector and Jerzy Adamski and Karsten Suhre},
journal = {Nat Genet},
title = {A genome-wide perspective of genetic variation in human metabolism},
abstract = {Serum metabolite concentrations provide a direct readout of biological processes in the human body, and they are associated with disorders such as cardiovascular and metabolic diseases. We present a genome-wide association study (GWAS) of 163 metabolic traits measured in human blood from 1,809 participants from the KORA population, with replication in 422 participants of the TwinsUK cohort. For eight out of nine replicated loci (FADS1, ELOVL2, ACADS, ACADM, ACADL, SPTLC3, ETFDH and SLC16A9), the genetic variant is located in or near genes encoding enzymes or solute carriers whose functions match the associating metabolic traits. In our study, the use of metabolite concentration ratios as proxies for enzymatic reaction rates reduced the variance and yielded robust statistical associations with P values ranging from 3 x 10(-24) to 6.5 x 10(-179). These loci explained 5.6%-36.3% of the observed variance in metabolite concentrations. For several loci, associations with clinically relevant parameters have been reported previously.},
affiliation = {Institute of Epidemiology, Helmholtz Zentrum M{\"u}nchen, German Research Center for Environmental Health, Neuherberg, Germany.},
number = {2},
pages = {137--41},
volume = {42},
year = {2010},
month = {Feb},
language = {eng},
date-added = {2010-02-02 11:25:42 +0100},
date-modified = {2010-02-02 11:25:42 +0100},
doi = {10.1038/ng.507},
pii = {ng.507},
pmid = {20037589},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Illig-2010-Nat%20Genet_A%20genome-wide%20perspe.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4889},
read = {Yes},
rating = {0}
}

@article{Rutter:1999p5940,
author = {M Rutter and J Silberg and T O'Connor and E Simonoff},
journal = {J Child Psychol Psychiatry},
title = {Genetics and child psychiatry: I Advances in quantitative and molecular genetics},
abstract = {Advances in quantitative psychiatric genetics as a whole are reviewed with respect to conceptual and methodological issues in relation to statistical model fitting, new genetic designs, twin and adoptee studies, definition of the phenotype, pervasiveness of genetic influences, pervasiveness of environmental influences, shared and nonshared environmental effects, and nature-nurture interplay. Advances in molecular genetics are discussed in relation to the shifts in research strategies to investigate multifactorial disorders (affected relative linkage designs, association strategies, and quantitative trait loci studies); new techniques and identified genetic mechanisms (expansion of trinucleotide repeats, genomic imprinting, mitochondrial DNA, fluorescent in-situ hybridisation, behavioural phenotypes, and animal models); and the successful localisation of genes.},
affiliation = {Institute of Psychiatry, London, UK.},
number = {1},
pages = {3--18},
volume = {40},
year = {1999},
month = {Jan},
language = {eng},
keywords = {Humans, Child: Preschool, Adolescent, Epidemiologic Methods, Child Psychiatry, Socioeconomic Factors, Genetics: Medical, Research Design, Models: Statistical, Adoption, Genetic Predisposition to Disease, Molecular Biology, Twin Studies as Topic, Mental Disorders, Male, Child, Social Environment, Female, Genetic Techniques},
date-added = {2010-02-18 23:16:32 +0100},
date-modified = {2010-07-29 19:32:47 +0200},
pmid = {10102724},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5940},
rating = {0}
}

@article{Chou:2009p9772,
author = {Yi-Yu Chou and Natasha Lepor{\'e} and Ming-Chang Chiang and Christina Avedissian and Marina Barysheva and Katie L McMahon and Greig I de Zubicaray and Matthew Meredith and Margaret J Wright and Arthur W Toga and Paul M Thompson},
journal = {Neuroimage},
title = {Mapping genetic influences on ventricular structure in twins},
abstract = {Despite substantial progress in measuring the anatomical and functional variability of the human brain, little is known about the genetic and environmental causes of these variations. Here we developed an automated system to visualize genetic and environmental effects on brain structure in large brain MRI databases. We applied our multi-template segmentation approach termed "Multi-Atlas Fluid Image Alignment" to fluidly propagate hand-labeled parameterized surface meshes, labeling the lateral ventricles, in 3D volumetric MRI scans of 76 identical (monozygotic, MZ) twins (38 pairs; mean age=24.6 (SD=1.7)); and 56 same-sex fraternal (dizygotic, DZ) twins (28 pairs; mean age=23.0 (SD=1.8)), scanned as part of a 5-year research study that will eventually study over 1000 subjects. Mesh surfaces were averaged within subjects to minimize segmentation error. We fitted quantitative genetic models at each of 30,000 surface points to measure the proportion of shape variance attributable to (1) genetic differences among subjects, (2) environmental influences unique to each individual, and (3) shared environmental effects. Surface-based statistical maps, derived from path analysis, revealed patterns of heritability, and their significance, in 3D. Path coefficients for the 'ACE' model that best fitted the data indicated significant contributions from genetic factors (A=7.3%), common environment (C=38.9%) and unique environment (E=53.8%) to lateral ventricular volume. Earlier-maturing occipital horn regions may also be more genetically influenced than later-maturing frontal regions. Maps visualized spatially-varying profiles of environmental versus genetic influences. The approach shows promise for automatically measuring gene-environment effects in large image databases.},
affiliation = {Department of Neurology, UCLA School of Medicine, Laboratory of Neuro Imaging, Los Angeles, CA 90095-7332, USA.},
number = {4},
pages = {1312--23},
volume = {44},
year = {2009},
month = {Feb},
language = {eng},
keywords = {Humans, Reproducibility of Results, Sensitivity and Specificity, Male, Twins, Cerebral Ventricles, Magnetic Resonance Imaging, Pilot Projects, Young Adult, Female},
date-added = {2010-03-26 19:18:13 +0100},
date-modified = {2010-03-26 19:18:13 +0100},
doi = {10.1016/j.neuroimage.2008.10.036},
pii = {S1053-8119(08)01152-X},
pmid = {19041405},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Chou-2009-Neuroimage_Mapping%20genetic%20infl.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9772},
rating = {0}
}

@article{Dahlman:2002p5299,
author = {Ingrid Dahlman and Iain A Eaves and Roman Kosoy and V Anne Morrison and Joanne Heward and Stephen C L Gough and Amit Allahabadia and Jayne A Franklyn and Jaakko Tuomilehto and Eva Tuomilehto-Wolf and Francesco Cucca and Cristian Guja and Constantin Ionescu-Tirgoviste and Helen Stevens and Philippa Carr and Sarah Nutland and Patricia McKinney and Julian P Shield and William Wang and Heather J Cordell and Neil Walker and John A Todd and Patrick Concannon},
journal = {Nat Genet},
title = {Parameters for reliable results in genetic association studies in common disease},
abstract = {It is increasingly apparent that the identification of true genetic associations in common multifactorial disease will require studies comprising thousands rather than the hundreds of individuals employed to date. Using 2,873 families, we were unable to confirm a recently published association of the interleukin 12B gene in 422 type I diabetic families. These results emphasize the need for large datasets, small P values and independent replication if results are to be reliable.},
affiliation = {JDRF/WT Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 2XY, UK.},
number = {2},
pages = {149--50},
volume = {30},
year = {2002},
month = {Feb},
language = {eng},
keywords = {Genetics: Population, 3' Untranslated Regions, Databases: Genetic, Humans, Interleukin-12, Linkage Disequilibrium, Diabetes Mellitus: Type 1, Polymorphism: Single Nucleotide},
date-added = {2010-02-09 22:29:21 +0100},
date-modified = {2010-02-09 22:29:22 +0100},
doi = {10.1038/ng825},
pii = {ng825},
pmid = {11799396},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5299},
rating = {0}
}

@article{Raevuori:2007p10255,
author = {Anu Raevuori and Danielle M Dick and Anna Keski-Rahkonen and Lea Pulkkinen and Richard J Rose and Aila Rissanen and Jaakko Kaprio and Richard J Viken and Karri Silventoinen},
journal = {Psychol Med},
title = {Genetic and environmental factors affecting self-esteem from age 14 to 17: a longitudinal study of Finnish twins},
abstract = {BACKGROUND: We analysed genetic and environmental influences on self-esteem and its stability in adolescence. METHOD: Finnish twins born in 1983-1987 were assessed by questionnaire at ages 14 (n = 4132 twin individuals) and 17 years (n = 3841 twin individuals). Self-esteem was measured using the Rosenberg global self-esteem scale and analyzed using quantitative genetic methods for twin data in the Mx statistical package. RESULTS: The heritability of self-esteem was 0.62 [95% confidence interval (CI) 0.56-0.68] in 14-year-old boys and 0.40 (95% CI 0.26-0.54) in 14-year-old girls, while the corresponding estimates at age 17 were 0.48 (95% CI 0.39-0.56) and 0.29 (95% CI 0.11-0.45). Rosenberg self-esteem scores at ages 14 and 17 were modestly correlated (r = 0.44 in boys, r = 0.46 in girls). In boys, the correlation was mainly (82%) due to genetic factors, with residual co-variation due to unique environment. In girls, genetic (31%) and common environmental (61%) factors largely explained the correlation. CONCLUSIONS: In adolescence, self-esteem seems to be differently regulated in boys versus girls. A key challenge for future research is to identify environmental influences contributing to self-esteem during adolescence and determine how these factors interact with genetic influences.},
affiliation = {Department of Public Health, University of Helsinki, Finland. anu.raevuori@helsinki.fi},
number = {11},
pages = {1625--33},
volume = {37},
year = {2007},
month = {Nov},
language = {eng},
keywords = {Age Factors, Adolescent, Sex Factors, Female, Longitudinal Studies, Self Concept, Twins, Male, Personality Assessment, Adolescent Psychology, Questionnaires, Social Environment, Personality, Humans, Finland, Family},
date-added = {2010-04-02 10:59:06 +0200},
date-modified = {2010-04-02 10:59:06 +0200},
doi = {10.1017/S0033291707000840},
pii = {S0033291707000840},
pmid = {17537282},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Raevuori-2007-Psychol%20Med_Genetic%20and%20environm.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10255},
rating = {0}
}

@article{Verweij:2010p5661,
author = {K J Verweij and B P Zietsch and M T Lynskey and S E Medland and M C Neale and N G Martin and Dorret I Boomsma and J M Vink},
journal = {Addiction},
title = {Genetic and environmental influences on cannabis use initiation and problematic use: a meta-analysis of twin studies},
abstract = {Background	Because cannabis use is associated with social, physical and psychological problems, it is important to know what causes some individuals to initiate cannabis use and a subset of those to become problematic users. Previous twin studies found evidence for both genetic and environmental influences on vulnerability, but due to considerable variation in the results it is difficult to draw clear conclusions regarding the relative magnitude of these influences. Methods	A systematic literature search identified 28 twin studies on cannabis use initiation and 24 studies on problematic cannabis use. The proportion of total variance accounted for by genes (A), shared environment (C) and unshared environment (E) in (i) initiation of cannabis use and (ii) problematic cannabis use was calculated by averaging corresponding A, C and E estimates across studies from independent cohorts and weighting by sample size. Results	For cannabis use initiation, A, C and E estimates were 48%, 25% and 27% in males and 40%, 39% and 21% in females. For problematic cannabis use A, C and E estimates were 51%, 20% and 29% for males and 59%, 15% and 26% for females. Confidence intervals of these estimates are considerably narrower than those in the source studies. Conclusions	Our results indicate that vulnerability to both cannabis use initiation and problematic use was influ- enced significantly by A, C and E. There was a trend for a greater C and lesser A component for cannabis use initiation compared to problematic use for females.},
pages = {417--430},
volume = {105},
year = {2010},
date-added = {2010-02-12 20:23:59 +0100},
date-modified = {2010-07-29 20:25:51 +0200},
doi = {10.1111/j.1360-0443.2009.02831.x},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Verweij-2010-Addiction_Genetic%20and%20environm.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5661},
rating = {0}
}

@article{Salvadore:2009p4421,
author = {Giacomo Salvadore and Allison C Nugent and Guang Chen and Nirmala Akula and Peixiong Yuan and Dara M Cannon and Carlos A Zarate and Francis J McMahon and Husseini K Manji and Wayne C Drevets},
journal = {Biol Psychiatry},
title = {Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans},
abstract = {BACKGROUND: Bcl-2 is a major regulator of neural plasticity and cellular resilience. A single nucleotide polymorphism (SNP) in the Bcl-2 gene, Bcl-2 rs956572, significantly modulates the expression of Bcl-2 protein and cellular vulnerability to apoptosis. We tested the hypothesis that this SNP would modulate gray matter (GM) volume in the limbic-cortical-striatal-pallidal-thalamic circuitry that plays major roles in mood regulation. METHODS: Forty-seven healthy subjects participated in this study (30 A carriers, 17 G homozygotes). Neuromorphometric differences between G homozygotes and A carriers were investigated using optimized voxel-based morphometry (VBM). Statistical significance was set at p < .05, corrected for multiple comparisons. RESULTS: A carriers showed less GM volume than G homozygotes in the left ventral striatum (p(corrected) < .05). CONCLUSIONS: Genetic variation in the Bcl-2 gene modulates GM volume in areas known to play key roles in the neurobiology of reward processes and emotion regulation and in the pathophysiology of mood disorders. Thus, the findings from the current study are noteworthy insofar as they converge with preclinical findings that Bcl-2 functions to enhance neuronal viability and might indirectly extend this evidence to humans.},
affiliation = {Mood and Anxiety Disorders Program, National Institute of Mental Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA. salvadoreg@mail.nih.gov},
number = {8},
pages = {804--7},
volume = {66},
year = {2009},
month = {Oct},
language = {eng},
keywords = {Adult, Alleles, Brain, Genes: bcl-2, Brain Mapping, Neural Pathways, Female, Genotype, Male, Humans, Middle Aged, Magnetic Resonance Imaging, Polymorphism: Single Nucleotide, Basal Ganglia, Organ Size},
date-added = {2010-01-29 10:29:11 +0100},
date-modified = {2010-01-29 10:29:11 +0100},
doi = {10.1016/j.biopsych.2009.05.025},
pii = {S0006-3223(09)00643-X},
pmid = {19589501},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4421},
rating = {0}
}

@article{Thornberry:1987,
author = {O T Jr Thornberry},
journal = {Vital Health Stat 2},
title = {An experimental comparison of telephone and personal health interview surveys.},
affiliation = {US Department of Health and Human Services, Public Health Service, National Center for Health Statistics, Division of Health Interview Statistics, Hyattsville, Maryland 20782, USA.},
number = {106},
pages = {1--4},
year = {1987},
language = {eng},
date-added = {2010-01-03 19:34:18 +0100},
date-modified = {2010-01-03 19:34:18 +0100},
pmid = {15791749},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p967},
rating = {0}
}

@article{Anonymous:2010p4640,
title = {Reliability issues and evidence},
date-added = {2010-01-30 15:47:56 +0100},
date-modified = {2010-07-24 11:42:13 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Reliability%20issues%20a-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4640},
rating = {0}
}

@article{Stein:2010p12295,
author = {Jason L Stein and Xue Hua and Jonathan H Morra and Suh Lee and Derrek P Hibar and April J Ho and Alex D Leow and Arthur W Toga and Jae Hoon Sul and Hyun Min Kang and Eleazar Eskin and Andrew J Saykin and Li Shen and Tatiana Foroud and Nathan Pankratz and Matthew J Huentelman and David W Craig and Jill D Gerber and April N Allen and Jason J Corneveaux and Dietrich A Stephan and Jennifer Webster and Bryan M Dechairo and Steven G Potkin and Clifford R Jack and Michael W Weiner and Paul M Thompson and Alzheimer's Disease Neuroimaging Initiative},
journal = {Neuroimage},
title = {Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease},
abstract = {In a genome-wide association study of structural brain degeneration, we mapped the 3D profile of temporal lobe volume differences in 742 brain MRI scans of Alzheimer's disease patients, mildly impaired, and healthy elderly subjects. After searching 546,314 genomic markers, 2 single nucleotide polymorphisms (SNPs) were associated with bilateral temporal lobe volume (P<5 x 10(-7)). One SNP, rs10845840, is located in the GRIN2B gene which encodes the N-methyl-d-aspartate (NMDA) glutamate receptor NR2B subunit. This protein - involved in learning and memory, and excitotoxic cell death - has age-dependent prevalence in the synapse and is already a therapeutic target in Alzheimer's disease. Risk alleles for lower temporal lobe volume at this SNP were significantly over-represented in AD and MCI subjects vs. controls (odds ratio=1.273; P=0.039) and were associated with mini-mental state exam scores (MMSE; t=-2.114; P=0.035) demonstrating a negative effect on global cognitive function. Voxelwise maps of genetic association of this SNP with regional brain volumes, revealed intense temporal lobe effects (FDR correction at q=0.05; critical P=0.0257). This study uses large-scale brain mapping for gene discovery with implications for Alzheimer's disease.},
affiliation = {Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Neuroscience Research Building 225E, 635 Charles Young Drive, Los Angeles, CA 90095-1769, USA.},
number = {2},
pages = {542--54},
volume = {51},
year = {2010},
month = {Jun},
language = {eng},
date-added = {2010-06-09 20:16:08 +0200},
date-modified = {2010-06-09 20:16:12 +0200},
doi = {10.1016/j.neuroimage.2010.02.068},
pii = {S1053-8119(10)00255-7},
pmid = {20197096},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Stein-2010-Neuroimage_Genome-wide%20analysis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12295},
rating = {5}
}

@article{Steiger:1996p2429,
author = {J H Steiger},
journal = {Multivariate Behavioral Research},
title = {Coming full circle in the history of factor indeterminacy},
number = {4},
pages = {617--630},
volume = {31},
year = {1996},
date-added = {2010-01-11 23:31:54 +0100},
date-modified = {2010-01-11 23:33:00 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Steiger-1996-Multivariate%20Behavioral%20Research_Coming%20full%20circle%20i.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2429},
rating = {0}
}

@article{Warnat:2005p13480,
author = {Patrick Warnat and Roland Eils and Benedikt Brors},
journal = {BMC Bioinformatics},
title = {Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes},
abstract = {BACKGROUND: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer studies. Although similar questions for the same type of cancer are addressed in these different studies, a comparative analysis of their results is hampered by the use of heterogeneous microarray platforms and analysis methods. RESULTS: In contrast to a meta-analysis approach where results of different studies are combined on an interpretative level, we investigate here how to directly integrate raw microarray data from different studies for the purpose of supervised classification analysis. We use median rank scores and quantile discretization to derive numerically comparable measures of gene expression from different platforms. These transformed data are then used for training of classifiers based on support vector machines. We apply this approach to six publicly available cancer microarray gene expression data sets, which consist of three pairs of studies, each examining the same type of cancer, i.e. breast cancer, prostate cancer or acute myeloid leukemia. For each pair, one study was performed by means of cDNA microarrays and the other by means of oligonucleotide microarrays. In each pair, high classification accuracies (> 85%) were achieved with training and testing on data instances randomly chosen from both data sets in a cross-validation analysis. To exemplify the potential of this cross-platform classification analysis, we use two leukemia microarray data sets to show that important genes with regard to the biology of leukemia are selected in an integrated analysis, which are missed in either single-set analysis. CONCLUSION: Cross-platform classification of multiple cancer microarray data sets yields discriminative gene expression signatures that are found and validated on a large number of microarray samples, generated by different laboratories and microarray technologies. Predictive models generated by this approach are better validated than those generated on a single data set, while showing high predictive power and improved generalization performance.},
affiliation = {Department of Theoretical Bioinformatics, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. p.warnat@dkfz.de},
pages = {265},
volume = {6},
year = {2005},
month = {Jan},
language = {eng},
keywords = {Prostatic Neoplasms, Animals, Male, Humans, Breast Neoplasms, Leukemia: Myeloid, Female, Oligonucleotide Array Sequence Analysis, Gene Expression Regulation: Neoplastic, Phenotype, Gene Expression Profiling},
date-added = {2010-07-01 20:43:43 +0200},
date-modified = {2010-07-01 20:43:44 +0200},
doi = {10.1186/1471-2105-6-265},
pii = {1471-2105-6-265},
pmid = {16271137},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Warnat-2005-BMC%20Bioinformatics_Cross-platform%20analy.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13480},
rating = {0}
}

@article{Hanson:2000p11298,
author = {B Hanson},
title = {IRT Parameter Estimation using the EM Algorithm},
year = {2000},
date-added = {2010-04-26 22:32:21 +0200},
date-modified = {2010-04-26 22:32:59 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Hanson-2000-_IRT%20Parameter%20Estima.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11298},
rating = {0}
}

@article{Storey2003,
author = {J Storey},
journal = {The Annals of Statistics},
title = {The positive false discovery rate: A Bayesian interpretation and the {\$}q{\$}-value},
number = {6},
pages = {2013--2035},
volume = {31},
year = {2003},
date-added = {2010-01-12 14:26:51 +0100},
date-modified = {2010-07-29 19:51:51 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2514},
rating = {0}
}

@article{Davies:2005p14222,
author = {S L Davies and AA Neath and J E Cavanaugh},
title = {Cross validation model selection criteria for linear regression based on the Kullback-Leibler discrepancy},
year = {2005},
date-added = {2010-08-22 21:04:50 +0200},
date-modified = {2010-08-22 21:06:35 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Davies-2005-_Cross%20validation%20mod.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14222},
rating = {0}
}

@techreport{Antonietti:2003b,
author = {J-P Antonietti},
journal = {Techreport},
title = {Designs de testage incomplets et mod{\`e}le non-param{\'e}trique de la r{\'e}ponse {\`a} l'item},
affiliation = {Institut de Math{\'e}matiques Appliqu{\'e}es},
year = {2003},
month = {Sep},
date-added = {2010-01-10 11:33:20 +0100},
date-modified = {2010-07-29 20:42:07 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Antonietti-2003-Techreport_Designs%20de%20testage%20i.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2088},
rating = {0}
}

@article{Baayen:2008p2920,
author = {R H Baayen},
title = {Analyzing Linguistic Data A practical introduction to statistics},
year = {2008},
date-added = {2010-01-13 21:55:05 +0100},
date-modified = {2010-01-13 22:05:15 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Baayen-2008-_Analyzing%20Linguistic.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2920},
rating = {0}
}

@article{Dolan:2000p3194,
author = {C V Dolan},
journal = {Multivariate Behavioral Research},
title = {Investigating Spearman's Hypothesis by Means of Multi-Group Confirmatory Factor Analysis},
abstract = {Differences between blacks and whites on cognitive ability tests have been attributed to a fundamental difference between these groups in general intelligence (or g, as it is denoted). The hypothesized difference in g gives rise to Spearman's hypothesis, which states that the differences in the means of the tests are related to the tests' factor loadings on g. Jensen has investigated this hypothesis by correlating differences in means and tests' g loadings. The aim of the present article is to investigate B-W differences using multi-group confirmatory factor analysis. The advantages of multi-group confirmatory factor analysis over Jensen's test of Spearman's hypothesis are discussed.
A published data set is analyzed. Strict factorial invariance is tested and judged to be tenable. Various models are tested, which do and do not incorporate g. It is observed that it is difficult to distinguish between several hypotheses, including and excluding g, concerning group differences. The inability to distinguish between competing models using multi-group confirmatory factor analysis makes it difficult to draw clear conclusions about the exact nature of black-white differences in cognitive abilities. The implications of the results for Jensen's test of Spearman's hypothesis are discussed.},
affiliation = {University of Amsterdam},
number = {1},
pages = {21--50},
volume = {35},
year = {2000},
date-added = {2010-01-14 20:52:41 +0100},
date-modified = {2010-01-14 20:53:34 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Dolan-2000-Multivariate%20Behavioral%20Research_Investigating%20Spearm-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3194},
rating = {0}
}

@article{McMichael:2000,
author = {AJ McMichael and R Beaglehole},
journal = {Lancet},
title = {The changing global context of public health},
abstract = {Future health prospects depend increasingly on globalisation processes and on the impact of global environmental change. Economic globalisation--entailng deregulated trade and investment--is a mixed blessing for health. Economic growth and the dissemination of technologies have widely enhanced life expectancy. However, aspects of globalisation are jeopardising health by eroding social and environmental conditions, exacerbating the rich-poor gap, and disseminating consumerism. Global environmental changes reflect the growth of populations and the intensity of economic activity. These changes include altered composition of the atmosphere, land degradation, depletion of terrestrial aquifers and ocean fisheries, and loss of biodiversity. This weakening of life-supporting systems poses health risks. Contemporary public health must therefore encompass the interrelated tasks of reducing social and health inequalities and achieving health-sustaining environments.},
pages = {495--499},
volume = {356},
year = {2000},
date-added = {2010-01-03 19:36:09 +0100},
date-modified = {2010-01-03 19:36:10 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1068},
rating = {0}
}

@article{Gigenrenzer:2004p3607,
author = {G Gigenrenzer and S Krauss and O Vitouch},
title = {The Null Ritual What You Always Wanted to Know About Significance Testing but Were Afraid to Ask},
annote = {No scientific worker has a fixed level of significance at which from year to year, and in all circumstances, he rejects hypotheses; he rather gives his mind to each particular case in the light of his evidence and his ideas. (Ronald A. Fisher, 1956, p. 42)},
year = {2004},
date-added = {2010-01-15 22:01:16 +0100},
date-modified = {2010-01-15 22:03:02 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gigenrenzer-2004-_The%20Null%20Ritual%20What.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3607},
rating = {0}
}

@article{Greimel:2010p4423,
author = {Ellen Greimel and Martin Schulte-R{\"u}ther and Tilo Kircher and Inge Kamp-Becker and Helmut Remschmidt and Gereon R Fink and Beate Herpertz-Dahlmann and Kerstin Konrad},
journal = {Neuroimage},
title = {Neural mechanisms of empathy in adolescents with autism spectrum disorder and their fathers},
abstract = {A deficit in empathy has been repeatedly described in individuals with autism spectrum disorder (ASD) and also, albeit less markedly, in their unaffected relatives. Here, we aimed to investigate the neural mechanisms of empathy in ASD, and to explore familial contributions to empathy correlates. Using functional magnetic resonance imaging, 15 boys with ASD, 11 fathers of adolescents with ASD, and two control groups comparable for age and IQ (n=15 typically developing boys and their fathers (n=9)) were investigated during an empathy task. Emotional faces were presented and participants were either asked to infer the emotional state from the face (other-task) or to judge their own emotional response to the face (self-task). When attributing emotions to self and other, the ASD group showed diminished fusiform gyrus activation compared to controls. Neural activity in the fusiform gyrus was inversely related to social deficits in ASD subjects. Moreover, when ASD subjects inferred their own emotional response to faces, they showed less congruent reactions and inferior frontal gyrus activity was decreased. Although fathers of ASD children scored higher on a self-rating scale for autistic symptoms compared to control fathers, their task performance was unimpaired. However, neurally, fathers of affected children also showed reduced fusiform gyrus activation when inferring others' emotions. Shared abnormalities in fusiform gyrus activation in affected adolescents and first-degree relatives suggest that this dysfunction constitutes a fundamental deviation in ASD. Moreover, the findings provide evidence that both aberrant neural face and mirroring mechanisms are implicated in empathy impairments in ASD.},
affiliation = {Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of the RWTH Aachen, Neuenhofer Weg 21, Germany. egreimel@ukaachen.de},
number = {1},
pages = {1055--65},
volume = {49},
year = {2010},
month = {Jan},
language = {eng},
keywords = {Behavior, Adolescent, Functional Laterality, Adult, Psychomotor Performance, Frontal Lobe, Executive Function, Neuropsychological Tests, Expressed Emotion, Data Interpretation: Statistical, Male, Humans, Photic Stimulation, Magnetic Resonance Imaging, Image Processing: Computer-Assisted, Autistic Disorder, Reaction Time, Empathy},
date-added = {2010-01-29 10:29:05 +0100},
date-modified = {2010-01-29 10:29:06 +0100},
doi = {10.1016/j.neuroimage.2009.07.057},
pii = {S1053-8119(09)00847-7},
pmid = {19647799},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4423},
rating = {0}
}

@article{Culhane:2002p11929,
author = {Aed{\'\i}n C Culhane and Guy Perri{\`e}re and Elizabeth C Considine and Thomas G Cotter and Desmond G Higgins},
journal = {Bioinformatics},
title = {Between-group analysis of microarray data},
abstract = {MOTIVATION: Most supervised classification methods are limited by the requirement for more cases than variables. In microarray data the number of variables (genes) far exceeds the number of cases (arrays), and thus filtering and pre-selection of genes is required. We describe the application of Between Group Analysis (BGA) to the analysis of microarray data. A feature of BGA is that it can be used when the number of variables (genes) exceeds the number of cases (arrays). BGA is based on carrying out an ordination of groups of samples, using a standard method such as Correspondence Analysis (COA), rather than an ordination of the individual microarray samples. As such, it can be viewed as a method of carrying out COA with grouped data. RESULTS: We illustrate the power of the method using two cancer data sets. In both cases, we can quickly and accurately classify test samples from any number of specified a priori groups and identify the genes which characterize these groups. We obtained very high rates of correct classification, as determined by jack-knife or validation experiments with training and test sets. The results are comparable to those from other methods in terms of accuracy but the power and flexibility of BGA make it an especially attractive method for the analysis of microarray cancer data.},
affiliation = {Department of Biochemistry, University College Cork, Cork, Ireland. A.Culhane@ucc.ie},
number = {12},
pages = {1600--8},
volume = {18},
year = {2002},
month = {Dec},
language = {eng},
keywords = {Gene Expression, Gene Expression Regulation, Sensitivity and Specificity, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Bone Neoplasms, Gene Expression Profiling, Transcription: Genetic, Models: Genetic, Oligonucleotide Array Sequence Analysis, Cluster Analysis, Leukemia: Myeloid: Acute, Models: Statistical, Reproducibility of Results, Software, Quality Control, Humans, Algorithms},
date-added = {2010-05-23 16:44:33 +0200},
date-modified = {2010-05-23 16:44:33 +0200},
pmid = {12490444},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Culhane-2002-Bioinformatics_Between-group%20analys.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11929},
rating = {0}
}

@article{Glynn:2010p12850,
author = {A N Glynn and J Wakefield},
journal = {Statistical Methodology},
title = {Ecological inference in the social sciences},
abstract = {Ecological inference is a problem of partial identification, and therefore precise conclusions are rarely possible without the col- lection of individual level (identifying) data. Without such data, sensitivity analyses provide the only recourse. In this paper we re- view and critique recent approaches to ecological inference in the social sciences, and describe in detail hierarchical models, which allow both sensitivity analysis and the incorporation of individual level data into an ecological analysis. A crucial element of a sensi- tivity analysis in such models is prior specification, and we detail how this may be carried out. Furthermore, we demonstrate how the inclusion of a small amount of individual level data from a small number of ecological areas can dramatically improve the properties of such estimates.},
pages = {307--322},
volume = {7},
year = {2010},
date-added = {2010-06-21 20:14:42 +0200},
date-modified = {2010-07-29 20:06:22 +0200},
doi = {10.1016/j.stamet.2009.09.003},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Glynn-2010-Statistical%20Methodology_Ecological%20inference.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12850},
rating = {0}
}

@article{Teresi:2006p11935,
author = {J A Teresi and A L Stewart and L S Morales and S M Stahl},
journal = {Med Care},
title = {Measurement in a Multi-Ethnic Society: Overview to the Special Issue},
number = {11},
pages = {S3--S4},
volume = {44},
year = {2006},
date-added = {2010-05-23 16:53:01 +0200},
date-modified = {2010-07-29 19:39:29 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Teresi-2006-Med%20Care_Measurement%20in%20a%20Mul.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11935},
rating = {4}
}

@article{Crane:2007p1825,
author = {Paul K Crane and Karynsa Cetin and Karon F Cook and Kurt Johnson and Richard Deyo and Dagmar Amtmann},
journal = {Qual Life Res},
title = {Differential item functioning impact in a modified version of the Roland-Morris Disability Questionnaire},
abstract = {OBJECTIVE: To evaluate a modified version of the Roland-Morris Disability Questionnaire for differential item functioning (DIF) related to several covariates. BACKGROUND: DIF occurs in an item when, after controlling for the underlying trait measured by the test, the probability of endorsing the item varies across groups. METHODS: Secondary data analysis of two studies of participants with back pain (total n = 875). We used a hybrid item response theory/ logistic regression approach for detecting DIF. We obtained scores that accounted for DIF. We evaluated the impact of DIF on individual and group scores, and compared scores that ignored or accounted for DIF in terms of the strength of association with SF-36 subscale scores. RESULTS: DIF was found in 18/23 items. Salient scale-level differential functioning was found related to age, education, and employment. Overall 24 participants (3%) had salient scale-level differential functioning. Mean scores across demographic groups differed minimally when accounting for DIF. The strength of association of scores with SF-36 scores was similar for scores that ignored and scores that accounted for DIF. CONCLUSIONS: The modified version of the Roland-Morris Disability Questionnaire appears to have largely negligible DIF related to the covariates assessed here.},
affiliation = {Department of Medicine, University of Washington, Harborview Medical Center, 325 Ninth Avenue, Box 359780, Seattle, WA 98104, USA. pcrane@u.washington.edu},
number = {6},
pages = {981--90},
volume = {16},
year = {2007},
month = {Aug},
language = {eng},
keywords = {Adolescent, Back Pain, Adult, Factor Analysis: Statistical, Questionnaires, Prospective Studies, Female, Sickness Impact Profile, Discriminant Analysis, Middle Aged, Psychometrics, Randomized Controlled Trials as Topic, Activities of Daily Living, Quality of Life, Male, Logistic Models, Outcome Assessment (Health Care), Disability Evaluation, Socioeconomic Factors, Humans},
date-added = {2010-01-09 22:59:57 +0100},
date-modified = {2010-07-29 19:48:28 +0200},
doi = {10.1007/s11136-007-9200-x},
pmid = {17443419},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1825},
rating = {0}
}

@article{Neale:1994p901,
author = {M C Neale and L J Eaves and K S Kendler},
journal = {Behav Genet},
title = {The power of the classical twin study to resolve variation in threshold traits},
abstract = {We explore the power of the twin study to resolve sources of familial resemblance when the data are measured at the binary or ordinal level. Four components of variance were examined: additive genetic, nonadditive genetic, and common and specific environment. Curves are presented to compare the power of the continuous case with those of threshold models corresponding to different prevalences in the population: 1, 5, 10, 25, and 50%. Approximately three times the sample size is needed for equivalent power to the continuous case when the threshold is at the optimal 50%, and this ratio increases to about 10 times when 10% are above threshold. Some power may be recovered by subdividing those above threshold to form three or more ordered classes, but power is determined largely by the lowest threshold. Non-random ascertainment of twins (i) through affected twins and examining their cotwins or (ii) through ascertainment of all pairs in which at least one twin is affected increases power. In most cases, strategy i is more efficient than strategy ii. Though powerful for the rarer disorders, these methods suffer the disadvantage that they rely on prior knowledge of the population prevalence. Furthermore, sampling from hospital cases may introduce biases, reducing their value. A useful approach may be to assess the population with a screening instrument; the power calculations indicate that sampling all concordant and half of the discordant pairs would be efficient, as along as the cost of screening is not too high.},
affiliation = {Department of Psychiatry, Medical College of Virginia, Box 710, 23298-0710 Richmond, Virginia},
number = {3},
pages = {239--258},
volume = {24},
year = {1994},
keywords = {sampling, research design, threshold traits, ascertainment, Twin study, selection, variance power},
date-added = {2010-01-03 18:30:10 +0100},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/BF01067191},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Neale-1994-Behav%20Genet_The%20power%20of%20the%20cla.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p901},
rating = {0}
}

@article{Ruiz:2007p9563,
author = {Lidia Ruiz and Roger Paredes and Guadalupe G{\'o}mez and Joan Romeu and Pere Domingo and Nuria P{\'e}rez-Alvarez and Giuseppe Tambussi and Josep Maria Llibre and Javier Mart{\'\i}nez-Picado and Francesc Vidal and Carmina R Fumaz and Bonaventura Clotet and TIBET Study Group},
journal = {AIDS},
title = {Antiretroviral therapy interruption guided by CD4 cell counts and plasma HIV-1 RNA levels in chronically HIV-1-infected patients},
abstract = {OBJECTIVE: We evaluated the safety of CD4 cell count and plasma HIV-1 RNA (pVL)-guided treatment interruptions (GTI) and determined predictors of duration of treatment interruption. METHODS: Chronically HIV-1-infected adults with sustained CD4 cell counts > 500 cells/microl and pVL < 50 copies/ml were randomly assigned to either continue with standard antiretroviral therapy (control group, n = 101) or to interrupt therapy aimed at maintaining CD4 cell counts > 350 cells/microl and pVL < 100,000 copies/ml (GTI group, n = 100). Both groups were followed for 2 years. RESULTS: There were no AIDS-defining illnesses or deaths in either group. Compared to controls, subjects interrupting therapy reduced treatment exposure by 67%, but suffered significantly more adverse events related to the intake of medication or to therapy interruption [relative hazard, 2.71; 95% confidence interval (CI), 1.64-4.49; P < 0.001), mainly due to an excess in mononucleosis-like symptoms. While GTI subjects demonstrated improvements in the psychosocial spheres of quality of life and pain reporting, GTI had no effect on the physical aspects of quality of life. Although both groups had a similar hazard for developing CD4 cell count < 200 cells/microl; at least 10% of subjects on GTI had CD4 cell counts < 350 cells/microl at every time point. Drug resistance mutations were detected in 36% of subjects but were selected de novo only in subjects interrupting non-nucleoside reverse transcriptase inhibitor therapy. Lower CD4 cell count nadir, higher set-point pVL and prior exposure to suboptimal regimens were all independent predictors of the need to reinitiate treatment. CONCLUSIONS: Overall, GTI were not as safe as continuing therapy. Despite achieving some improvements in quality of life, GTI did not reduce the overall rate of management-related adverse events.},
affiliation = {Fundaci{\'o} IrsiCaixa and HIV Clinical Unit, Hospital Universitari Germans Trias i Pujol, Universitat Auton{\`o}ma de Barcelona, Badalona, Spain.},
number = {2},
pages = {169--78},
volume = {21},
year = {2007},
month = {Jan},
language = {eng},
keywords = {HIV Infections, Viral Load, Female, Quality of Life, Middle Aged, Epidemiologic Methods, Adult, RNA: Viral, Aged, Humans, Patient Compliance, Anti-HIV Agents, Antiretroviral Therapy: Highly Active, Drug Administration Schedule, CD4 Lymphocyte Count, HIV-1, Male, Disease Progression, Chronic Disease},
date-added = {2010-03-23 20:55:06 +0100},
date-modified = {2010-07-29 19:12:25 +0200},
doi = {10.1097/QAD.0b013e328011033a},
pii = {00002030-200701110-00006},
pmid = {17197807},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ruiz-2007-AIDS_Antiretroviral%20thera.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9563},
rating = {0}
}

@article{McMillan:2005p4645,
author = {G McMillan and T Hanson},
journal = {Journal of Statistical Software},
title = {SAS Macro BDM for Fitting the Dale Regression Model to Bivariate Ordinal Response Data},
abstract = {A SAS macro for fitting an extension of the Dale (1986) regression model to bivariate ordinal data is provided. The macro is described in detail and examples from Dale (1986) and McMillan, Hanson, Bedrick, and Lapham (2005) are discussed.},
number = {2},
volume = {14},
year = {2005},
date-added = {2010-01-30 15:55:52 +0100},
date-modified = {2010-01-30 15:56:30 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/McMillan-2005-Journal%20of%20Statistical%20Software_SAS%20Macro%20BDM%20for%20Fi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4645},
rating = {0}
}

@article{Hung:2009p7758,
author = {H M James Hung and Sue-Jane Wang},
journal = {J Biopharm Stat},
title = {Some controversial multiple testing problems in regulatory applications},
abstract = {Multiple testing problems in regulatory applications are often more challenging than the problems of handling a set of mathematical symbols representing multiple null hypotheses under testing. In the union-intersection setting, it is important to define a family of null hypotheses relevant to the clinical questions at issue. The distinction between primary endpoint and secondary endpoint needs to be considered properly in different clinical applications. Without proper consideration, the widely used sequential gate keeping strategies often impose too many logical restrictions to make sense, particularly to deal with the problem of testing multiple doses and multiple endpoints, the problem of testing a composite endpoint and its component endpoints, and the problem of testing superiority and noninferiority in the presence of multiple endpoints. Partitioning the null hypotheses involved in closed testing into clinical relevant orderings or sets can be a viable alternative to resolving the illogical problems requiring more attention from clinical trialists in defining the clinical hypotheses or clinical question(s) at the design stage. In the intersection-union setting there is little room for alleviating the stringency of the requirement that each endpoint must meet the same intended alpha level, unless the parameter space under the null hypothesis can be substantially restricted. Such restriction often requires insurmountable justification and usually cannot be supported by the internal data. Thus, a possible remedial approach to alleviate the possible conservatism as a result of this requirement is a group-sequential design strategy that starts with a conservative sample size planning and then utilizes an alpha spending function to possibly reach the conclusion early.},
affiliation = {Division of Biometrics I, OB/OTS/CDER, FDA, Silver Spring, Maryland 20993-0002, USA. hsienming.hung@fda.hhs.gov},
number = {1},
pages = {1-11; discussion 12--41},
volume = {19},
year = {2009},
month = {Jan},
language = {eng},
keywords = {United States Food and Drug Administration, Drug Approval, Clinical Trials as Topic, Humans, Models: Statistical, Research Design, Probability, Endpoint Determination, Algorithms, United States, Sample Size, Treatment Outcome, Pharmaceutical Preparations},
date-added = {2010-03-17 20:53:31 +0100},
date-modified = {2010-07-29 19:32:23 +0200},
doi = {10.1080/10543400802541693},
pii = {907426452},
pmid = {19127460},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7758},
rating = {0}
}

@article{Sakai:2009p2500,
author = {Joseph T Sakai and Michael C Stallings and Thomas J Crowley and Heather L Gelhorn and Matthew B McQueen and Marissa A Ehringer},
journal = {Drug Alcohol Depend},
title = {Test of association between GABRA2 (SNP rs279871) and adolescent conduct/alcohol use disorders utilizing a sample of clinic referred youth with serious substance and conduct problems, controls and available first degree relatives},
abstract = {Recent findings have linked the GABRA2 gene with antisocial personality disorder and alcohol dependence (AD) in adults and conduct disorder (CD), but not AD symptoms, in children and adolescents. We sought to replicate previous findings and test for an association between a single nucleotide polymorphism (SNP) in the GABRA2 gene (rs279871) and CD among adolescents. METHODS: Adolescent patients (n=371), 13-18 years old, were recruited from a university substance abuse treatment program. Patient siblings (n=245), parents of patients (n=355), adolescent controls (n=185), siblings of controls (n=163) and parents of controls (n=263) were included in these analyses (total sample n=1582). Case-control (using only Caucasian and Hispanic probands) and family-based association tests were completed to test for association between rs279871 and several a priori CD and AD phenotypes. RESULTS: For case-control association tests, rs279871 was significantly associated with CD (p=0.02) but not AD phenotypes; the result did not survive strict correction for multiple testing. All family-based association tests were non-significant (CD p=0.48; CD symptom count age corrected within sex p=0.91; AD p=0.84; alcohol use disorder p=0.52). CONCLUSIONS: Consistent with previous findings, the results do not support the association between GABRA2 SNP rs279871 and AD in adolescents. Our results also do not support an association between rs279871 and CD; the study limitations are reviewed.},
affiliation = {Division of Substance Dependence, University of Colorado Denver School of Medicine, Aurora, CO, United States.},
pages = {},
year = {2009},
month = {Sep},
language = {ENG},
date-added = {2010-01-12 13:35:44 +0100},
date-modified = {2010-01-12 13:35:45 +0100},
doi = {10.1016/j.drugalcdep.2009.08.015},
pii = {S0376-8716(09)00348-2},
pmid = {19783384},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sakai-2009-Drug%20Alcohol%20Depend_Test%20of%20association.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2500},
rating = {0}
}

@article{Parsad:2010p4274,
author = {R Parsad},
title = {Nested block design},
date-added = {2010-01-23 22:01:34 +0100},
date-modified = {2010-01-23 22:01:58 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Parsad--_Nested%20block%20design.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4274},
rating = {0}
}

@article{Wickham:2007p10898,
author = {H Wickham},
journal = {Journal of Statistical Software},
title = {Reshaping Data with the reshape Package},
abstract = {This paper presents the reshape package for R, which provides a common framework for many types of data reshaping and aggregation. It uses a paradigm of `melting' and `casting', where the data are `melted' into a form which distinguishes measured and iden- tifying variables, and then `cast' into a new shape, whether it be a data frame, list, or high dimensional array. The paper includes an introduction to the conceptual framework, practical advice for melting and casting, and a case study.},
number = {12},
volume = {21},
year = {2007},
date-added = {2010-04-11 13:45:59 +0200},
date-modified = {2010-04-11 13:46:43 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wickham-2007-Journal%20of%20Statistical%20Software_Reshaping%20Data%20with.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10898},
rating = {0}
}

@article{Sweeting:2008p383,
author = {M J Sweeting and D De Angelis and M Hickman and A E Ades},
journal = {Biostatistics},
title = {Estimating hepatitis C prevalence in England and Wales by synthesizing evidence from multiple data sources. Assessing data conflict and model fit},
abstract = {Multiparameter evidence synthesis is becoming widely used as a way of combining evidence from multiple and often disparate sources of information concerning a number of parameters. Synthesizing data in one encompassing model allows propagation of evidence and learning. We demonstrate the use of such an approach in estimating the number of people infected with the hepatitis C virus (HCV) in England and Wales. Data are obtained from seroprevalence studies conducted in different subpopulations. Each subpopulation is modeled as a composition of 3 main HCV risk groups (current injecting drug users (IDUs), ex-IDUs, and non-IDUs). Further, data obtained on the prevalence (size) of each risk group provide an estimate of the prevalence of HCV in the whole population. We simultaneously estimate all model parameters through the use of Bayesian Markov chain Monte Carlo techniques. The main emphasis of this paper is the assessment of evidence consistency and investigation of the main drivers for model inferences. We consider a cross-validation technique to reveal data conflict and leverage when each data source is in turn removed from the model.},
affiliation = {MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK. michael.sweeting@mrc-bsu.cam.ac.uk},
number = {4},
pages = {715--34},
volume = {9},
year = {2008},
month = {Oct},
language = {eng},
keywords = {Odds Ratio, Female, Markov Chains, Regression Analysis, Substance Abuse: Intravenous, Models: Statistical, Likelihood Functions, Databases: Factual, Monte Carlo Method, Sex Factors, Prevalence, Seroepidemiologic Studies, Bias (Epidemiology), Male, Algorithms, Hepatitis C, Bayes Theorem, Humans, Blood Donors, England, Pregnancy, Models: Biological, Age Factors, Wales},
date-added = {2010-01-03 11:51:59 +0100},
date-modified = {2010-01-03 11:51:59 +0100},
doi = {10.1093/biostatistics/kxn004},
pii = {kxn004},
pmid = {18349037},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sweeting-2008-Biostatistics_Estimating%20hepatitis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p383},
rating = {0}
}

@article{Cleves:2005p1551,
author = {M A Cleves},
journal = {The Stata Joumal},
title = {Exploratory analysis of single nucleotide polymorphism (SNP) for quantitative traits},
abstract = {With the decreasing cost and the increasing ability to quickly genotype single nucleotide polymorphisms (SNP) across the human genome, large databases containing possibly hundreds of typed SNPs are becoming common in population- based studies of quantitative traits. Testing for association between individual SNPs and the quantitative trait is an important first step in the discovery of disease susceptibility SNPs. This task, however, could be time-consuming and tedious if a large number of SNPs is involved. In this article, I introduce two new commands designed to facilitate the screening and testing of multiple SNPs for possible association with quantitative traits.},
affiliation = {UAMS College of Medicine, Department of Pediatrics 11219 Financial Centre Parkway, Suite 250, Little Rock, AR 72211},
number = {2},
pages = {141--153},
volume = {5},
year = {2005},
date-added = {2010-01-07 16:36:44 +0100},
date-modified = {2010-07-29 19:53:40 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Cleves-2005-The%20Stata%20Joumal_Exploratory%20analysis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1551},
read = {Yes},
rating = {0}
}

@article{Lee:2006p12325,
author = {S-I Lee and V Ganapathi and D Koller},
journal = {NIPS},
title = {Efficient Structure Learning of Markov Networks using L1-Regularization},
abstract = {Markov networks are commonly used in a wide variety of applications, ranging from computer vision, to natural language, to computational biology. In most current applications, even those that rely heavily on learned models, the structure of the Markov network is constructed by hand, due to the lack of effective algo- rithms for learning Markov network structure from data. In this paper, we provide a computationally efficient method for learning Markov network structure from data. Our method is based on the use of L1 regularization on the weights of the log-linear model, which has the effect of biasing the model towards solutions where many of the parameters are zero. This formulation converts the Markov net- work learning problem into a convex optimization problem in a continuous space, which can be solved using efficient gradient methods. A key issue in this setting is the (unavoidable) use of approximate inference, which can lead to errors in the gradient computation when the network structure is dense. Thus, we explore the use of different feature introduction schemes and compare their performance. We provide results for our method on synthetic data, and on two real world data sets: pixel values in the MNIST data, and genetic sequence variations in the human HapMap data. We show that our L1-based method achieves considerably higher generalization performance than the more standard L2-based method (a Gaussian parameter prior) or pure maximum-likelihood learning. We also show that we can learn MRF network structure at a computational cost that is not much greater than learning parameters alone, demonstrating the existence of a feasible method for this important problem.},
year = {2006},
date-added = {2010-06-12 09:44:02 +0200},
date-modified = {2010-07-29 19:41:58 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Lee-2006-NIPS_Efficient%20Structure.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12325},
rating = {0}
}

@article{Munafo:2005p10528,
author = {M R Munaf{\`o} and T Clark and J Flint},
journal = {Mol Psychiatry},
title = {Does measurement instrument moderate the association between the serotonin transporter gene and anxiety-related personality traits? A meta-analysis},
abstract = {We attempted to replicate the findings of two recent meta-analyses that personality inventory moderates the association between the serotonin transporter gene and anxiety-related traits. A total of 24 studies contributed to the meta-analysis, of which three reported genotype frequencies that deviated from Hardy-Weinberg (HW) equilibrium. We found some support for the view that results depend on the type of questionnaire used, although in a direction opposite to that

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repo_name: sergiud/bibtex-spirit

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