text:
},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p882},
rating = {0}
}

@article{Gorwood:2007p9134,
author = {Philip Gorwood and Mathias Wohl and Yann Le Strat and Fr{\'e}d{\'e}ric Rouillon},
journal = {C R Biol},
title = {Gene-environment interactions in addictive disorders: epidemiological and methodological aspects},
abstract = {The gene-environment interactions' approach could explain some epidemiological and clinical factors associated with addictive behaviours. Twin studies first help to disentangle the respective roles of environment and genetic effects, finding convincing evidence for common genetic vulnerability in several addictive behaviours, and helping to delimit what syndrome could belong to the addictive disorder spectrum. Assessing gene x environment interaction (G x E) needs specifically designed studies, using multiplicative or additive approaches. Focusing on this G x E interaction already showed its relevancy in many recent studies, using both epidemiological and molecular approaches. For example, in a non-human primate model of alcohol dependence assessing the respective role of genetic vulnerability (having the short allele located in the promoter region of the gene coding for the serotonin transporter) and severe fostering conditions (as locked up in a cage with other inmates for the first six months of life), the only group of monkeys that has a significant risk of using spontaneously alcohol is the one that gathers both risk factors, i.e. being peer-raised and having the short allele. Such approach could help to more accurately select specific candidate genes, to identify more homogenous subgroups of patients (as sharing the same genetic vulnerability), to understand how genetic factors mediate the risk of associated psychiatric disorders, and ultimately, may lead to more focused, i.e. more efficient, prevention strategies.},
affiliation = {Inserm U675, Institut f{\'e}d{\'e}ratif de recherche (IFR 02), facult{\'e} Xavier-Bichat, 16, rue Henri-Huchard, 75018 Paris, France. philip.gorwood@lmr.aphp.fr},
number = {4},
pages = {329--38},
volume = {330},
year = {2007},
month = {Apr},
language = {eng},
keywords = {Prevalence, France, Age Distribution, Substance-Related Disorders, Socioeconomic Factors, Environment, Male, Ethnic Groups, Female, Humans},
date-added = {2010-03-22 13:28:40 +0100},
date-modified = {2010-03-22 13:28:40 +0100},
doi = {10.1016/j.crvi.2007.02.017},
pii = {S1631-0691(07)00115-1},
pmid = {17502289},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gorwood-2007-C%20R%20Biol_Gene-environment%20int.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9134},
rating = {0}
}

@article{Scollnik:1996p2315,
author = {D P M Scollnik},
title = {An introduction to Markov Chain Monte Carlo methods and their actuarial applications},
abstract = {This paper introduces the readers of the Proceed- ings to an important class of computer based simula- tion techniques known as Markov chain Monte Carlo (MCMC) methods. General properties characterizing these methods will be discussed, but the main empha- sis will be placed on one MCMC method known as the Gibbs sampler. The Gibbs sampler permits one to simu- late realizations from complicated stochastic models in high dimensions by making use of the model's associated full conditional distributions, which will generally have a much simpler and more manageable form. In its most extreme version, the Gibbs sampler reduces the analy- sis of a complicated multivariate stochastic model to the consideration of that model's associated univariate full conditional distributions.
In this paper, the Gibbs sampler will be illustrated with four examples. The first three of these examples serve as rather elementary yet instructive applications of the Gibbs sampler. The fourth example describes a reasonably sophisticated application of the Gibbs sam- pler in the important arena of credibility for classifica- tion ratemaking via hierarchical models, and involves the Bayesian prediction of frequency counts in workers compensation insurance.},
year = {1996},
date-added = {2010-01-10 12:30:19 +0100},
date-modified = {2010-01-10 12:31:26 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Scollnik-1996-_An%20introduction%20to%20M.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2315},
rating = {0}
}

@article{InternationalHapMapConsortium:2005p3264,
author = {International HapMap Consortium},
journal = {Nature},
title = {A haplotype map of the human genome},
abstract = {Inherited genetic variation has a critical but as yet largely uncharacterized role in human disease. Here we report a public database of common variation in the human genome: more than one million single nucleotide polymorphisms (SNPs) for which accurate and complete genotypes have been obtained in 269 DNA samples from four populations, including ten 500-kilobase regions in which essentially all information about common DNA variation has been extracted. These data document the generality of recombination hotspots, a block-like structure of linkage disequilibrium and low haplotype diversity, leading to substantial correlations of SNPs with many of their neighbours. We show how the HapMap resource can guide the design and analysis of genetic association studies, shed light on structural variation and recombination, and identify loci that may have been subject to natural selection during human evolution.},
number = {7063},
pages = {1299--320},
volume = {437},
year = {2005},
month = {Oct},
language = {eng},
keywords = {Genome: Human, Chromosomes: Human: Y, Haplotypes, DNA: Mitochondrial, Humans, Polymorphism: Single Nucleotide, Recombination: Genetic, Linkage Disequilibrium, Selection: Genetic, Gene Frequency},
date-added = {2010-01-14 21:04:18 +0100},
date-modified = {2010-07-29 19:40:35 +0200},
doi = {10.1038/nature04226},
pmid = {16255080},
local-url = {file://localhost/Users/chl/Dropbox/Papers/International%20HapMap%20Consortium-2005-Nature_A%20haplotype%20map%20of%20t.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3264},
rating = {0}
}

@article{Prowker:2007,
author = {A Prowker and G Camilli},
journal = {Journal of Educational Measurement},
title = {Looking Beyond the Overall Scores of NAEP Assessments: Applications of Generalized Linear Mixed Modeling for Exploring Value-Added Item Difficulty Effects},
number = {1},
pages = {69--87},
volume = {44},
year = {2007},
date-added = {2010-01-10 11:33:10 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Prowker-2007-Journal%20of%20Educational%20Measurement_Looking%20Beyond%20the%20O.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2160},
rating = {0}
}

@article{Hampel:2004p8508,
author = {H Hampel and A Mitchell and K Blennow and R A Frank and S Brettschneider and L Weller and H-J M{\"o}ller},
journal = {J Neural Transm},
title = {Core biological marker candidates of Alzheimer's disease - perspectives for diagnosis, prediction of outcome and reflection of biological activity},
abstract = {Alzheimer's disease (AD) is a complex neurodegenerative dementing illness. Over the past few years, however, remarkable advances have taken place in understanding both the genetic and molecular biology with the intracellular processing of amyloid and tau and the changes leading to the pathologic formation of extracellular amyloid plaques and the intraneuronal aggregation of hyperphosphorylated tau into neurofibrillary tangles. This progress in our understanding of the molecular pathology has set the stage for clinically meaningful advances in the development of biomarkers. Emerging diagnostic methods that are based on biochemical and imaging biomarkers of disease specific pathology hold the potential to provide effective measures of natural history (marker of disease that is predictive of outcome), biological activity (such as magnitude and frequency of response correlating with drug potency) and markers of surrogate endpoints (single or composite marker that accounts for clinical benefit of the therapy). Markers of biological activity should be also evaluated regarding their value to reflect disease progression, heterogeneity of the clinical population, for early decision making and characterization of new treatments. We focussed on the current status of core analytes which provide reasonable evidence for association with key mechanisms of pathogenesis or neurodegeneration in AD. In addition, feasibility was important, such as availability of a validated assay for the biological measure in question, with properties that included high precision and reliability of measurement, reagents and standards well described. On this basis we reviewed the body of literature that has examined CSF total tau (t-tau) and beta-amyloid 1-42 (Abeta(1-42)), phosphorylated tau (p-tau) and beta-amyloid-antibodies as diagnostic tests for AD versus clinically representative comparison groups. Measurement of t-tau and Abeta(1-42) in the CSF seems useful to discriminate early and incipient AD from age-associated memory-impairment, depression, and some secondary dementias. First studies showed that measurement of p-tau proteins significantly improves early and differential diagnosis, as well as disease prediction in subjects at risk for AD and comes closest to fulfilling proposed criteria of a biological marker for AD. However, the nature of the majority of reported findings are still preliminary and retrospective. General issues for biomarkers have to be adequately addressed, such as sensitivity of the method, frequency of assessments, stability of the method, standardization of methods and dynamic range. There is still a partial lack of comparison patient populations that must be addressed in future studies. International dementia networks have been recently established to advance the establishment of core biomarker candidates of AD as potential surrogate endpoints for clinical trials and their clinical use for predictive and diagnostic purposes.},
affiliation = {Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig-Maximilian University, Munich, Germany. hampel@psy.med.uni-muenchen.de},
number = {3},
pages = {247--72},
volume = {111},
year = {2004},
month = {Mar},
language = {eng},
keywords = {Humans, Prognosis, Alzheimer Disease, Phosphorylation, Biological Markers, tau Proteins, Antibodies, Amyloid beta-Protein},
date-added = {2010-03-21 19:38:15 +0100},
date-modified = {2010-03-21 19:38:16 +0100},
doi = {10.1007/s00702-003-0065-z},
pmid = {14991453},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8508},
rating = {0}
}

@article{Vermunt:2008p6247,
author = {Jeroen K Vermunt},
journal = {Stat Methods Med Res},
title = {Latent class and finite mixture models for multilevel data sets},
abstract = {An extension of latent class (LC) and finite mixture models is described for the analysis of hierarchical data sets. As is typical in multilevel analysis, the dependence between lower-level units within higher-level units is dealt with by assuming that certain model parameters differ randomly across higher-level observations. One of the special cases is an LC model in which group-level differences in the logit of belonging to a particular LC are captured with continuous random effects. Other variants are obtained by including random effects in the model for the response variables rather than for the LCs. The variant that receives most attention in this article is an LC model with discrete random effects: higher-level units are clustered based on the likelihood of their members belonging to the various LCs. This yields a model with mixture distributions at two levels, namely at the group and the subject level. This model is illustrated with three rather different empirical examples. The appendix describes an adapted version of the expectation-maximization algorithm that can be used for maximum likelihood estimation, as well as providing setups for estimating the multilevel LC model with generally available software.},
affiliation = {Department of Methodology and Statistics, Tilburg University, Tilburg, The Netherlands. j.k.vermunt@uvt.nl},
number = {1},
pages = {33--51},
volume = {17},
year = {2008},
month = {Feb},
language = {eng},
keywords = {Intelligence Tests, Anti-Bacterial Agents, Bayes Theorem, Models: Statistical, Algorithms, Epilepsy, Poisson Distribution, Humans, Finite Element Analysis},
date-added = {2010-02-19 21:24:00 +0100},
date-modified = {2010-02-19 21:24:00 +0100},
doi = {10.1177/0962280207081238},
pii = {0962280207081238},
pmid = {17855746},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Vermunt-2008-Stat%20Methods%20Med%20Res_Latent%20class%20and%20fin.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6247},
read = {Yes},
rating = {0}
}

@article{Altman:1999,
author = {Douglas G Altman and JM Bland},
journal = {British Medical Journal},
title = {Treatment allocation in controlled trials: why randomise?},
abstract = {Since 1991 the BMJ has had a policy of not publishing trials that have not been properly randomised, except in rare cases where this can be justified.1 Why? The simplest approach to evaluating a new treatment is to compare a single group of patients given the new treatment with a group previously treated with an alternative treatment. Usually such studies compare two consecutive series of patients in the same hospital(s). This approach is seriously flawed. Problems will arise from the mixture of retrospective and prospective studies, and we can never satisfactorily eliminate possible biases due to other factors (apart from treatment) that may have changed over time. Sacks et al compared trials of the same treatments in which randomised or historical controls were used and found a consistent tendency for historically controlled trials to yield more optimistic results than randomised trials.2 The use of historical controls can be justified only in tightly controlled situations of relatively rare conditions, such as in evaluating treatments for advanced cancer.},
pages = {1209},
volume = {318},
year = {1999},
date-added = {2010-01-03 19:36:10 +0100},
date-modified = {2010-07-29 20:20:56 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1078},
rating = {0}
}

@article{Gilbert:2009p3286,
author = {H N Gilbert and K S Pollard and M J van der Laan and S Dudoit},
journal = {U.C. Berkeley Division of Biostatistics Working Paper Series},
title = {Resampling-Based Multiple Hypothesis Testing with Applications to Genomics: New Developments in the R/Bioconductor Package multtest},
abstract = {The multtest package is a standard Bioconductor package containing a suite of functions useful for executing, summarizing, and displaying the results from a wide variety of multiple testing procedures (MTPs). In addition to many popular MTPs, the central methodological focus of the multtest package is the imple- mentation of powerful joint multiple testing procedures. Joint MTPs are able to account for the dependencies between test statistics by effectively making use of (estimates of) the test statistics joint null distribution. To this end, two additional bootstrap-based estimates of the test statistics joint null distribution have been developed for use in the package. For asymptotically linear estimators involv- ing single-parameter hypotheses (such as tests of means, regression parameters, and correlation parameters using t-statistics), a computationally efficient joint null distribution estimate based on influence curves is now also available. New MTPs implemented in multtest include marginal adaptive procedures for control of the false discovery rate (FDR) as well as empirical Bayes joint MTPs which can con- trol any Type I error rate defined as a function of the numbers of false positives and true positives. Examples of such error rates include, among others, the family- wise error rate and the FDR. S4 methods are available for objects of the new class EBMTP, and particular attention has been given to reducing the need for repeated resampling between function calls.},
number = {249},
year = {2009},
date-added = {2010-01-14 21:17:21 +0100},
date-modified = {2010-07-29 19:55:06 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gilbert-2009-U.C.%20Berkeley%20Division%20of%20Biostatistics%20Working%20Paper%20Series_Resampling-Based%20Mul.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3286},
rating = {0}
}

@misc{Lunz:2007,
author = {M E Lunz},
journal = {Miscellaneous},
title = {Examination Development Guidelines},
year = {2007},
date-added = {2010-01-10 11:33:19 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Lunz-2007-Miscellaneous_Examination%20Developm.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2103},
rating = {0}
}

@article{Mullen:2009p3098,
author = {S A Mullen and D E Crompton and P W Carney and I Helbig and S F Berkovic},
journal = {Neurology},
title = {A neurologist's guide to genome-wide association studies},
abstract = {Genome-wide association studies are utilized for gene discovery in common diseases. Genotypes of large groups of unrelated patients are compared to controls. This has become feasible due to the recent technical advances in genomics and convincing positive results are now regularly being published. This review is an accessible introduction to the genetic and technical knowledge needed to interpret such studies. Genome-wide association studies are being applied to many neurologic diseases. Here we use idiopathic generalized epilepsy as an example to highlight the phenotyping, sample size, and statistical issues that must be addressed in such studies. These studies are likely to transform our understanding of complex neurologic diseases in the next few years.},
affiliation = {Epilepsy Research Centre and Department of Medicine (Neurology), University of Melbourne, Austin Health, 145 Studley Rd., Heidelberg, Victoria 3084, Australia.},
number = {6},
pages = {558--65},
volume = {72},
year = {2009},
month = {Feb},
language = {eng},
keywords = {Clinical Trials as Topic, Humans, Polymorphism: Single Nucleotide, Chromosome Mapping, Genome-Wide Association Study, Genetic Predisposition to Disease, Nervous System Diseases},
date-added = {2010-01-14 20:18:35 +0100},
date-modified = {2010-01-14 20:18:35 +0100},
doi = {10.1212/01.wnl.0000341942.29513.bd},
pii = {72/6/558},
pmid = {19204266},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3098},
rating = {0}
}

@article{Robinson:2010p4882,
author = {R Robinson},
journal = {PLoS Biol},
title = {Common Disease, Multiple Rare (and Distant) Variants},
number = {1},
volume = {8},
year = {2010},
date-added = {2010-02-02 11:21:51 +0100},
date-modified = {2010-07-29 19:43:53 +0200},
doi = {10.1371/journal.pbio.1000293.g001},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Robinson-2010-PLoS%20Biol_Common%20Disease%20Mult.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4882},
rating = {0}
}

@article{Falissard:2006p1665,
author = {B Falissard},
journal = {International Journal of Methods in Psychiatric Research},
title = {The unidimensionality of a psychiatric scale: a statistical point of view},
abstract = {In quantitative psychopathology, one of the most crucial questions is whether a set of items measure just one thing in common. This property may be defined as unidimensionality. After a formal definition of unidimensionality, this paper discusses the use of the different tools traditionally related to this area. For quantitative measurements, factor analysis remains a good approach, goodness-of-fit tests, however, are of questionable value. Cronbach's alpha coefficient is more related to reliability than unidimensionality. The scree plot and the proportion of variance accounted for by the first principal component are, in practice, interesting tools. Item response theory leads to models that require unidimensionality to obtain efficient estimates of latent attributes; these methods, however, are not really adapted for assessing the unidimensionality of a set of items. Finally, even if unidimensionality is a fundamental psychometric property, there is a need for general multidimensional instruments that reflect the heterogeneity of psychiatric disorders.},
number = {3},
pages = {162--167},
volume = {8},
year = {2006},
keywords = {validity, measurement, psychometric},
date-added = {2010-01-08 21:59:07 +0100},
date-modified = {2010-07-29 19:29:50 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Falissard-2006-International%20Journal%20of%20Methods%20in%20Psychiatric%20Research_The%20unidimensionalit.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1665},
rating = {0}
}

@article{Mellenbergh:1996p12888,
author = {Gideon J Mellenbergh},
journal = {Psychological Methods},
title = {Measurement Precision in Test Score and Item Response Models},
abstract = {The population-dependent concept of reliability is used in test score models such as classical test theory and the binomial error model, whereas in item response mod- els, the population-independent concept of information is used. Reliability and information apply to both test score and item response models. Information is a conditional definition of precision, that is, the precision for a given subject; reli- ability is an unconditional definition, that is, the precision for a population of subjects. Information and reliability do not distinguish test score and item response models. The main distinction is that the parameters are specific for the test and the subject in test score models, whereas in item response models, the item parameters are separated from the subject parameters.},
number = {3},
pages = {293--299},
volume = {1},
year = {1996},
date-added = {2010-06-24 13:17:42 +0200},
date-modified = {2010-06-24 13:18:31 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mellenbergh-1996-Psychological%20Methods_Measurement%20Precisio.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12888},
rating = {4}
}

@article{Wu:2008,
author = {Shu-Fang Vivienne Wu and Mary Courtney and Helen Edwards and Jan McDowell and Lillie M Shortridge-Baggett and Pei-Jen Chang},
journal = {J Formos Med Assoc},
title = {Psychometric properties of the Chinese version of the Perceived Therapeutic Efficacy Scale for type 2 diabetes.},
abstract = {BACKGROUND/PURPOSE: The purpose of this study was to test the psychometric properties of the Perceived Therapeutic Efficacy Scale (PTES) for type 2 diabetes with a Taiwanese sample. The mortality rate and health care cost of diabetes have dramatically increased in Taiwan, with many people with diabetes lacking the ability to control their disease appropriately. Addressing this problem requires enhancing self-efficacy towards self-management. Thus, there is a particular need for research into developing a diabetes-specific self-efficacy measurement instrument in Taiwan. METHODS: This study was undertaken in two stages. Stage 1 consisted of forward and back translation of the PTES into Chinese and examination of content validity. Stage 2 established the validity and reliability of the Chinese version of PTES (C-PTES). A total of 230 people with type 2 diabetes aged 30 years or more from a diabetes outpatient clinic and taking oral medicine were recruited for psychometric testing. RESULTS: Significant criterion-related validity was demonstrated between the C-PTES and the Summary of Diabetes Self-Care Activities scores (r=0.32; p<0.01). Convergent validity was confirmed as the C-PTES converged well with the General Self-Efficacy Scale in measuring self-efficacy (r=0.42; p<0.01); construct validity using factor analysis composed a single subscale. Internal consistency showed Cronbach's alpha was 0.95 and the test-retest reliability (Pearson's correction) was 0.79 (p<0.01) and a Bland-Altman plot showed that 97% of the subjects were within two standard deviations of the mean. CONCLUSION: The results of reliability and validity strengthen confidence in using the C-PTES. The C-PTES requires future studies to confirm the psychometric properties.},
affiliation = {Faculty of Nursing, National Taipei College of Nursing, Taipei, Taiwan. shufang@ntcn.edu.tw},
number = {3},
pages = {232--238},
volume = {107},
year = {2008},
month = {Mar},
language = {eng},
date-added = {2010-01-03 19:38:21 +0100},
date-modified = {2010-01-03 19:38:22 +0100},
pmid = {18400608},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1138},
rating = {0}
}

@article{Quaye:2009p4954,
author = {Lydia Quaye and Jonathan Tyrer and Susan J Ramus and Honglin Song and Eva Wozniak and Richard A DiCioccio and Valerie McGuire and Estrid H{\o}gdall and Claus H{\o}gdall and Jan Blaakaer and Ellen L Goode and Joellen M Schildkraut and Douglas F Easton and Susanne Kr{\"u}ger-Kjaer and Alice S Whittemore and Simon A Gayther and Paul D P Pharoah},
journal = {PLoS ONE},
title = {Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer},
abstract = {BACKGROUND: Recent studies have identified several single nucleotide polymorphisms (SNPs) in the population that are associated with variations in the risks of many different diseases including cancers such as breast, prostate and colorectal. For ovarian cancer, the known highly penetrant susceptibility genes (BRCA1 and BRCA2) are probably responsible for only 40% of the excess familial ovarian cancer risks, suggesting that other susceptibility genes of lower penetrance exist. METHODS: We have taken a candidate approach to identifying moderate risk susceptibility alleles for ovarian cancer. To date, we have genotyped 340 SNPs from 94 candidate genes or regions, in up to 1,491 invasive epithelial ovarian cancer cases and 3,145 unaffected controls from three different population based studies from the UK, Denmark and USA. RESULTS: After adjusting for population stratification by genomic control, 18 SNPs (5.3%) were significant at the 5% level, and 5 SNPs (1.5%) were significant at the 1% level. The most significant association was for the SNP rs2107425, located on chromosome 11p15.5, which has previously been identified as a susceptibility allele for breast cancer from a genome wide association study (P-trend = 0.0012). When SNPs/genes were stratified into 7 different pathways or groups of validation SNPs, the breast cancer associated SNPs were the only group of SNPs that were significantly associated with ovarian cancer risk (P-heterogeneity = 0.0003; P-trend = 0.0028; adjusted (for population stratification) P-trend = 0.006). We did not find statistically significant associations when the combined data for all SNPs were analysed using an admixture maximum likelihood (AML) experiment-wise test for association (P-heterogeneity = 0.051; P-trend = 0.068). CONCLUSION: These data suggest that a proportion of the SNPs we evaluated were associated with ovarian cancer risk, but that the effect sizes were too small to detect associations with individual SNPs.},
affiliation = {Gynaecological Cancer Research Laboratories, UCL EGA Institute for Women's Health, University College London, London, United Kingdom.},
number = {6},
pages = {e5983},
volume = {4},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Genetic Variation, Humans, Polymorphism: Single Nucleotide, Ovarian Neoplasms, Aged: 80 and over, Aged, Case-Control Studies, Family Health, Neoplasm Invasiveness, Genetic Predisposition to Disease, Adult, Risk, Female, Genotype, Middle Aged},
date-added = {2010-02-03 21:01:02 +0100},
date-modified = {2010-02-03 21:01:02 +0100},
doi = {10.1371/journal.pone.0005983},
pmid = {19543528},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Quaye-2009-PLoS%20ONE_Association%20between.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4954},
rating = {0}
}

@book{CJE:2000,
author = {S Robinson},
journal = {Book},
title = {Canadian Journal of Education},
number = {4},
volume = {25},
year = {2000},
date-added = {2010-01-10 11:33:20 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Robinson-2000-Book_Canadian%20Journal%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1983},
rating = {0}
}

@techreport{Verstralen:2000,
author = {H H F M Verstralen and N D Verhelst},
journal = {Techreport},
title = {IRT models for subjective weights of options of multiple choice questions},
affiliation = {Cito},
year = {2000},
date-added = {2010-01-10 11:33:18 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Verstralen-2000-Techreport_IRT%20models%20for%20subje.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2120},
rating = {0}
}

@article{Valdano:2007p11910,
author = {S G Valdano and J A Di Rienzo},
title = {Discovering meaningful groups in hierarchical cluster analysis. An extension to the multivariate case of a multiple comparison method based on cluster analysis},
abstract = {In	the	framework	of	univariate	pairwise	comparison	procedures, Di Rienzo et al.[1] developed a hybrid technique joining a hierarchical clustering method with the principles of hypothesis testing. This paper presents an extension to the multivariate case. The new method gives an answer, on the bases of inferencial statistics, to the problem of determining the number of groups in hierarchical cluster analysis when there are replicates. Although, the method was developed as a test for the general hypothesis of equality of population centroids, it performs very well, considering size and power, as a pairwise comparison algorithm. Moreover it avoids the lack of transitivity of classical pairwise comparisons methods that yields to logical inconsistencies. The method is evaluated and compared, by Monte Carlo simulation, with a partitioning multivariate procedure proposed by Bozdogan and with a multiple comparison algorithm based on the Hotelling's T2 statistic. An example of grouping provenances of a native South American tree is presented.},
year = {2007},
date-added = {2010-05-23 11:59:08 +0200},
date-modified = {2010-05-23 12:00:19 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Valdano-2007-_Discovering%20meaningf.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11910},
rating = {4}
}

@article{Miettunen:2006p12156,
author = {J Miettunen and L Kantoj{\"a}rvi and J Veijola and M R J{\"a}rvelin and M Joukamaa},
journal = {Personality and Individual Differences},
title = {International comparison of Cloninger's temperament dimensions},
abstract = {Cloninger's Tridimensional Personality Questionnaire (TPQ) and Temperament and Character Inven- tory (TCI) have been developed to measure the following temperament dimensions: novelty seeking (NS), harm avoidance (HA), reward dependence (RD) and persistence (P). We used our previous Finnish normative study of the TPQ and TCI (Miettunen et al., 2004) to estimate correction coefficients to convert TPQ scales to comparable TCI scales. Our aim was to compare these corrected temperament dimension scores across 20 countries adjusting for study sample differences in age and gender. In all, some variations were found in these temperament scores between countries. Differences were especially apparent between the Asian and the Western countries. By far the lowest mean score of the RD was in Japan (11.2 vs. 15.4 for other countries; effect size Cohen's d = 5.74; z-test p < 0.001) and the highest mean score in P was in USA (5.5 vs. 4.4; d = 4.24, p = 0.001). Some of the findings could be explained by sample differences (e.g. age and education); while some may reflect real differences in the ways which personality is related to cultural factors, such as individualism/collectivism. These differences should be considered when interpret- ing studies with data on TPQ/TCI from different countries.},
pages = {1515--1526},
volume = {41},
year = {2006},
date-added = {2010-05-30 10:37:09 +0200},
date-modified = {2010-05-30 10:39:46 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Miettunen-2006-Personality%20and%20Individual%20Differences_International%20compar.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12156},
rating = {0}
}

@article{Haberman:2010p12921,
author = {S J Haberman and S Sinharay},
journal = {Psychometrika},
title = {Reporting of subscores using multidimensional item response theory},
abstract = {Recently, there has been increasing interest in reporting subscores. This paper examines reporting of subscores using multidimensional item response theory (MIRT) models (e.g., Reckase in Appl. Psychol. Meas. 21:25--36, 1997; C.R. Rao and S. Sinharay (Eds), Handbook of Statistics, vol. 26, pp. 607--642, North-Holland, Amsterdam, 2007; Beguin {\&} Glas in Psychometrika, 66:471--488, 2001). A MIRT model is fitted using a stabilized Newton--Raphson algorithm (Haberman in The Analysis of Frequency Data, University of Chicago Press, Chicago, 1974; Sociol. Methodol. 18:193--211, 1988) with adaptive Gauss-- Hermite quadrature (Haberman, von Davier, {\&} Lee in ETS Research Rep. No. RR-08-45, ETS, Princeton, 2008). A new statistical approach is proposed to assess when subscores using the MIRT model have any added value over (i) the total score or (ii) subscores based on classical test theory (Haberman in J. Educ. Behav. Stat. 33:204--229, 2008; Haberman, Sinharay, {\&} Puhan in Br. J. Math. Stat. Psychol. 62:79--95, 2008). The MIRT-based methods are applied to several operational data sets. The results show that the subscores based on MIRT are slightly more accurate than subscore estimates derived by classical test theory.},
number = {2},
pages = {209--227},
volume = {75},
year = {2010},
date-added = {2010-06-24 18:04:17 +0200},
date-modified = {2010-06-24 18:05:26 +0200},
doi = {10.1007/S11336-010-9158-4},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Haberman-2010-Psychometrika_Reporting%20of%20subscor.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12921},
rating = {4}
}

@article{Friend:2009p7645,
author = {Angela Friend and John C DeFries and Richard K Olson and Bruce Pennington and Nicole Harlaar and Brian Byrne and Stefan Samuelsson and Erik G Willcutt and Sally J Wadsworth and Robin Corley and Janice M Keenan},
journal = {Behav Genet},
title = {Heritability of high reading ability and its interaction with parental education},
abstract = {Moderation of the level of genetic influence on children's high reading ability by environmental influences associated with parental education was explored in two independent samples of identical and fraternal twins from the United States and Great Britain. For both samples, the heritability of high reading performance increased significantly with lower levels of parental education. Thus, resilience (high reading ability despite lower environmental support) is more strongly influenced by genotype than is high reading ability with higher environmental support. This result provides a coherent account when considered alongside results of previous research showing that heritability for low reading ability decreased with lower levels of parental education.},
affiliation = {Department of Psychology, University of Colorado At Boulder, Boulder, CO 80309, USA. angela.friend@colorado.edu},
number = {4},
pages = {427--36},
volume = {39},
year = {2009},
month = {Jul},
language = {eng},
keywords = {Twins: Dizygotic, United States, Reading, Educational Status, Models: Genetic, Male, Epistasis: Genetic, Longitudinal Studies, Parents, Genotype, Aptitude, Twins: Monozygotic, Cross-Cultural Comparison, Child: Gifted, Female, Child, Verbal Learning, Regression Analysis, Phenotype, Social Environment, Great Britain, Humans},
date-added = {2010-03-15 23:16:22 +0100},
date-modified = {2010-07-29 20:09:07 +0200},
doi = {10.1007/s10519-009-9263-2},
pmid = {19296213},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Friend-2009-Behav%20Genet_Heritability%20of%20high.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7645},
rating = {0}
}

@article{Collins:2006p9562,
author = {Pamela Y Collins and Alea R Holman and Melvyn C Freeman and Vikram Patel},
journal = {AIDS},
title = {What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review},
abstract = {The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental illness in developing countries examines the mental health risk factors for HIV, mental health consequences of HIV, psychosocial interventions of relevance for HIV-infected and affected populations, and highlights the relevance of these data for HIV care and treatment programs. We reviewed seven studies that measured the prevalence of HIV infection among clinic and hospital-based populations of people with mental illness or assessed sexual risk behavior in these populations; 30 studies that described the mental health consequences of HIV infection; and two reports of psychosocial interventions. The review demonstrates the need for methodologically sound studies of mental health throughout the course of HIV, including factors that support good mental health, and interventions that employ identified variables (e.g. coping, family support) for efficacy in reducing symptoms of mental illness. Promising intervention findings should encourage investigators to begin to study the implementation of these interventions in HIV service settings.},
number = {12},
pages = {1571--82},
volume = {20},
year = {2006},
month = {Aug},
language = {eng},
keywords = {HIV Infections, Anti-Retroviral Agents, Acquired Immunodeficiency Syndrome, Quality of Life, Interpersonal Relations, Cognition Disorders, Mental Disorders, Humans, Stress: Psychological, Prevalence, Family, Risk Factors},
date-added = {2010-03-23 20:54:47 +0100},
date-modified = {2010-07-29 19:12:25 +0200},
doi = {10.1097/01.aids.0000238402.70379.d4},
pii = {00002030-200608010-00001},
pmid = {16868437},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Collins-2006-AIDS_What%20is%20the%20relevanc.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9562},
rating = {0}
}

@article{Royston:2005p4068,
author = {P Royston and W Sauerbrei},
journal = {Methods Inf Med},
title = {Building multivariable regression models with continuous covariates in clinical epidemiology--with an emphasis on fractional polynomials},
abstract = {OBJECTIVES: In fitting regression models, data analysts must often choose a model based on several candidate predictor variables which may influence the outcome. Most analysts either assume a linear relationship for continuous predictors, or categorize them and postulate step functions. By contrast, we propose to model possible non-linearity in the relationship between the outcome and several continuous predictors by estimating smooth functions of the predictors. We aim to demonstrate that a structured approach based on fractional polynomials can give a broadly satisfactory practical solution to the problem of simultaneously identifying a subset of 'important' predictors and determining the functional relationship for continuous predictors. METHODS: We discuss the background, and motivate and describe the multivariable fractional polynomial (MFP) approach to model selection from data which include continuous and categorical predictors. We compare our results with those from other approaches in examples. We present a small simulation study to compare the functional form of the relationship obtained by fitting fractional polynomials and splines to a single predictor variable. RESULTS: We illustrate the advantages of the MFP approach over standard techniques of model construction in two real example datasets analyzed with logistic and Cox regression models, respectively. In the simulation study, fractional polynomial models had lower mean square error and more realistic behaviour than comparable spline models. CONCLUSIONS: In many practical situations, the MFP approach can satisfy the aim of finding models that fit the data well and also are simple, interpretable and potentially transportable to other settings.},
affiliation = {Cancer Division, MRC Clinical Trials Unit, London, UK. patrick.royston@ctu.mrc.ac.uk},
number = {4},
pages = {561--71},
volume = {44},
year = {2005},
month = {Jan},
language = {eng},
keywords = {Epidemiologic Research Design, Regression Analysis, Models: Statistical, Humans, Risk Factors, Proportional Hazards Models, Computer Simulation, Prognosis, Algorithms},
date-added = {2010-01-19 15:49:45 +0100},
date-modified = {2010-01-19 15:49:45 +0100},
pmid = {16342923},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4068},
rating = {0}
}

@article{Valentini:2006p2929,
author = {Giorgio Valentini},
journal = {Bioinformatics},
title = {Clusterv: a tool for assessing the reliability of clusters discovered in DNA microarray data},
abstract = {We present a new R package for the assessment of the reliability of clusters discovered in high-dimensional DNA microarray data. The package implements methods based on random projections that approximately preserve distances between examples in the projected subspaces.},
affiliation = {DSI, Dipartimento di Scienze dell'Informazione, Universit{\`a} degli Studi di Milano, Via Comelico 39, Italy. valentini@dsi.unimi.it},
number = {3},
pages = {369--70},
volume = {22},
year = {2006},
month = {Feb},
language = {eng},
keywords = {Models: Genetic, Online Systems, Sensitivity and Specificity, Computer Simulation, Reproducibility of Results, Genetic Variation, Software, Models: Statistical, Pattern Recognition: Automated, Gene Expression Profiling, Artificial Intelligence, Cluster Analysis, Oligonucleotide Array Sequence Analysis},
date-added = {2010-01-13 22:17:23 +0100},
date-modified = {2010-01-13 22:17:23 +0100},
doi = {10.1093/bioinformatics/bti817},
pii = {bti817},
pmid = {16332708},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Valentini-2006-Bioinformatics_Clusterv%20a%20tool%20for.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2929},
rating = {0}
}

@article{Wu:2009p1511,
author = {Michael C Wu and Xihong Lin},
journal = {Stat Methods Med Res},
title = {Prior biological knowledge-based approaches for the analysis of genome-wide expression profiles using gene sets and pathways},
abstract = {An increasing challenge in analysis of microarray data is how to interpret and gain biological insight of profiles of thousands of genes. This article provides a review of statistical methods for analysis of microarray data by incorporating prior biological knowledge using gene sets and biological pathways, which consist of groups of biologically similar genes. We first discuss issues of individual gene analysis. We compare several methods for analysis of gene sets including over-representation anlaysis, gene set enrichment analysis, principal component analysis, global test and kernel machine. We discuss the assumptions of these methods and their pros and cons. We illustrate these methods by application to a type II diabetes data set.},
affiliation = {Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA. mwu@hsph.harvard.edu},
number = {6},
pages = {577--93},
volume = {18},
year = {2009},
month = {Dec},
language = {eng},
date-added = {2010-01-07 12:26:48 +0100},
date-modified = {2010-01-07 12:26:48 +0100},
doi = {10.1177/0962280209351925},
pii = {18/6/577},
pmid = {20048386},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wu-2009-Stat%20Methods%20Med%20Res_Prior%20biological%20kno.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1511},
rating = {0}
}

@article{Jylha:2010p7293,
author = {Marja Jylh{\"a}},
journal = {Soc Sci Med},
title = {Self-rated health between psychology and biology. A response to Huisman and Deeg},
abstract = {In their commentary on my article "What is self-rated health and why does it predict mortality? Towards a unified conceptual model", Martin Huisman and Dorly Deeg argue, first, that the model I suggest may exaggerate the rational elements in the process of assessment and ignore the irrational and illogical influences; and, second, that self-rated health should be best understood not as a measure of "true health", but as a measure of people's perceptions about their health. My response to these comments attempts to clarify the nature of the model as a tool for describing the conceptual and logical structure of the evaluation, not the empirical process itself. Psychological and external influences, including "irrational" elements, can be understood as belonging to the contextual framework of evaluation. There is no question that self-rated health represents individual self-perceptions, but to explain its association with mortality it is crucial to understand its relationship to the biological and physiological states of the organism.},
affiliation = {School of Public Health, University of Tampere, Finland. marja.jylha@uta.fi},
number = {5},
pages = {655--7},
volume = {70},
year = {2010},
month = {Mar},
language = {eng},
date-added = {2010-03-10 20:19:25 +0100},
date-modified = {2010-03-10 20:19:25 +0100},
doi = {10.1016/j.socscimed.2009.11.004},
pii = {S0277-9536(09)00757-6},
pmid = {19959269},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7293},
rating = {0}
}

@article{Cleveland:1984p9532,
author = {W S Cleveland and R McGill},
journal = {JAMA},
title = {Graphical Perception: Theory, Experimentation, and Application to the Development of Graphical Methods},
number = {387},
pages = {531--554},
volume = {79},
year = {1984},
date-added = {2010-03-23 20:26:10 +0100},
date-modified = {2010-07-29 20:01:36 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Cleveland-1984-JAMA_Graphical%20Perception.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9532},
rating = {0}
}

@article{McCormick:1997p13847,
author = {C C McCormick and L R Goldberg},
title = {Two at a time is better than one at a time: Exploiting the horizontal aspects of factor representations},
year = {1997},
date-added = {2010-07-29 17:23:07 +0200},
date-modified = {2010-07-29 17:24:07 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/McCormick-1997-_Two%20at%20a%20time%20is%20bet.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13847},
rating = {0}
}

@article{Revicki:2006p8515,
author = {Dennis A Revicki and David Cella and Ron D Hays and Jeff A Sloan and William R Lenderking and Neil K Aaronson},
journal = {Health Qual Life Outcomes},
title = {Responsiveness and minimal important differences for patient reported outcomes},
abstract = {Patient reported outcomes provide the patient's perspective on the effectiveness of treatment. The draft Food and Drug Administration guidance on patient reported outcomes for labeling and promotional claims raises a number of method and measurement issues that require further clarification, including methods of determining responsiveness and minimal important differences. For clinical trials, instruments need to be based on a clear conceptual framework, have evidence supporting content validity and acceptable psychometric qualities. The measures must also have evidence documenting responsiveness and interpretation guidelines (i.e., minimal important difference) to be most useful as effectiveness endpoints in clinical trials. The recommended approach is to estimate the minimal important difference based on several anchor-based methods, with relevant clinical or patient-based indicators, and to examine various distribution-based estimates (i.e., effect size, standardized response mean, standard error of measurement) as supportive information, and then to triangulate on a single value or small range of values for the MID. Confidence in a specific MID value evolves over time and is confirmed by additional research evidence, including clinical trial experience. The MID may vary by population and context, and no one MID will be valid for all study applications involving a PRO instrument. Responsiveness and MID must be demonstrated and documented for the particular study population, and these measurement characteristics are needed for PRO labeling and promotional claims.},
affiliation = {Center for Health Outcomes Research, United Biosource Corporation, 7101 Wisconsin Ave., Suite 600, Bethesda, MD 20814, USA. dennis.revicki@unitedbiosource.com},
pages = {70},
volume = {4},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Quality of Life, Reproducibility of Results, Evidence-Based Medicine, Treatment Outcome, Psychometrics, Product Labeling, Humans, Endpoint Determination, United States Food and Drug Administration, Questionnaires, Drug Labeling, Patient Satisfaction, Clinical Trials as Topic, United States},
date-added = {2010-03-21 20:39:24 +0100},
date-modified = {2010-07-29 20:13:56 +0200},
doi = {10.1186/1477-7525-4-70},
pii = {1477-7525-4-70},
pmid = {17005038},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Revicki-2006-Health%20Qual%20Life%20Outcomes_Responsiveness%20and%20m.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8515},
rating = {0}
}

@article{Patterson:2006p5066,
author = {Nick Patterson and Alkes L Price and David Reich},
journal = {PLoS Genet},
title = {Population structure and eigenanalysis},
abstract = {Current methods for inferring population structure from genetic data do not provide formal significance tests for population differentiation. We discuss an approach to studying population structure (principal components analysis) that was first applied to genetic data by Cavalli-Sforza and colleagues. We place the method on a solid statistical footing, using results from modern statistics to develop formal significance tests. We also uncover a general "phase change" phenomenon about the ability to detect structure in genetic data, which emerges from the statistical theory we use, and has an important implication for the ability to discover structure in genetic data: for a fixed but large dataset size, divergence between two populations (as measured, for example, by a statistic like FST) below a threshold is essentially undetectable, but a little above threshold, detection will be easy. This means that we can predict the dataset size needed to detect structure.},
affiliation = {Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.},
number = {12},
pages = {e190},
volume = {2},
year = {2006},
month = {Dec},
language = {eng},
keywords = {Genetic Variation, Principal Component Analysis, Genetics: Medical, Genetic Markers, Models: Statistical, Genetics: Population, Computer Simulation, Humans, Models: Genetic},
date-added = {2010-02-05 20:09:29 +0100},
date-modified = {2010-02-05 20:09:29 +0100},
doi = {10.1371/journal.pgen.0020190},
pii = {06-PLGE-RA-0101R3},
pmid = {17194218},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Patterson-2006-PLoS%20Genet_Population%20structure.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5066},
rating = {0}
}

@article{Reiter:2004p3548,
author = {M Reiter and T Melzer},
title = {Ridge-Penalty Regularization for Kernel-CCA},
abstract = {CCA and Kernel-CCA are powerful statistical tools that have been successfully employed for feature extraction. However, when working in high-dimensional signal spaces, care has to be taken to avoid overfitting. This paper discusses the influence of ridge penalty regulariza- tion on kernel-CCA by relating it to multivariate linear regression(MLR) and partial least squares(PLS). Experimental results of a pose estimation task will be given.},
year = {2004},
date-added = {2010-01-15 21:00:30 +0100},
date-modified = {2010-01-15 21:01:06 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Reiter-2004-_Ridge-Penalty%20Regula.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3548},
rating = {0}
}

@article{Zietsch:2010p12572,
author = {B P Zietsch and K J H Verweij and J M Bailey and M J Wright and N G Martin},
journal = {Behav Genet},
title = {Genetic and environmental influences on risky sexual behaviour and its relationship with personality},
abstract = {Risky sexual behaviour is a major health issue in society, and it is therefore important to understand factors that may predispose individuals to such behaviour. Research suggests a link between risky sexual behaviour and personality, but the basis of this link remains unknown. Hans Eysenck proposed that personality is related to sexual behaviour via biological underpinnings of both. Here we test the viability of this perspective by analysing data from identical and non-identical twins (N = 4,904) who completed a questionnaire assessing sexual attitudes and behaviour as well as personality. Using genetic modelling of the twin data, we found that risky sexual behaviour was significantly positively correlated with Impulsivity (r = .27), Extraversion (r = .24), Psychoticism (r = .20), and Neuroticism (r = .09), and that in each case the correlation was due primarily to overlapping genetic influences. These findings suggest that the genetic influences that shape our personality may also predispose us to risky sexual behaviour.},
affiliation = {Genetic Epidemiology Unit, Queensland Institute of Medical Research, 300 Herston Rd, Brisbane, QLD 4029, Australia. Brendan.Zietsch@qimr.edu.au},
number = {1},
pages = {12--21},
volume = {40},
year = {2010},
month = {Jan},
language = {eng},
keywords = {Adolescent, Female, Likelihood Functions, Adult, Male, Middle Aged, Twins: Dizygotic, Risk-Taking, Models: Genetic, Humans, Impulsive Behavior, Sexual Behavior, Twins: Monozygotic, Extraversion (Psychology), Unsafe Sex},
date-added = {2010-06-15 22:23:31 +0200},
date-modified = {2010-07-29 20:09:07 +0200},
doi = {10.1007/s10519-009-9300-1},
pmid = {19813084},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Zietsch-2010-Behav%20Genet_Genetic%20and%20environm.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12572},
rating = {4}
}

@article{Christensen:2007p2689,
author = {K B Christensen and S Kreiner},
journal = {Applied Psychological Measurement},
title = {A Monte Carlo Approach to Unidimensionality Testing in Polytomous Rasch Models},
abstract = {Many statistical tests are designed to test the different assumptions of the Rasch model, but only few are directed at detecting multidimensionality. The Martin-Lo ̈ f test is an attractive approach, the disadvantage being that its null distribution deviates strongly from the asymptotic chi-square distribution for most realistic sample sizes. A Monte Carlo test approach to p value computation is proposed and is shown to yield a powerful test. Repeated and sequential Monte Carlo tests that can greatly reduce computing time are discussed.},
number = {1},
pages = {20--30},
volume = {31},
year = {2007},
date-added = {2010-01-13 10:09:41 +0100},
date-modified = {2010-07-29 19:16:52 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Christensen-2007-Applied%20Psychological%20Measurement_A%20Monte%20Carlo%20Approa.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2689},
rating = {0}
}

@article{Pelckmans:2006p3277,
author = {K Pelckmans and S Van Vooren and B Coessens and J A K Suykens and B De Moor},
title = {Mutual Spectral Clustering: Microarray Experiments Versus Text Corpus},
abstract = {This work studies a machine learning technique designed for exploring relations between microarray experiment data and the corpus of gene-related liter- ature available via PubMed. The use of this task is found in that it provides better clusters of genes by fusing both information sources together, while it can also be used to guide the expert through the large corpus of gene-related literature based on insights into microarray experiments and vice versa. The learning technique addresses the unsupervised learning problem of finding meaningful clusters co-occurring in both knowledge-bases. Here, one is typically interested in whether the membership of an instance to one cluster in the former knowledge-base transduces to membership of the same instance to the corresponding cluster in the latter representation. This idea is de- scribed as an extended MINCUT problem and implemented using a spectral clustering technique possessing a well-defined out-of-sample extension.},
year = {2006},
date-added = {2010-01-14 21:09:53 +0100},
date-modified = {2010-01-14 21:10:54 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Pelckmans-2006-_Mutual%20Spectral%20Clus.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3277},
rating = {0}
}

@article{BartvanderWorp:2010p11306,
author = {H Bart van der Worp and D W Howells and E S Sena and M J Porritt and S Rewell and V O'Collins and M R Macleod},
journal = {PLoS Med},
title = {Can Animal Models of Disease Reliably Inform Human Studies?},
number = {3},
pages = {e1000245},
volume = {7},
year = {2010},
date-added = {2010-04-26 23:01:46 +0200},
date-modified = {2010-04-26 23:03:42 +0200},
doi = {10.1371/journal.pmed.1000245},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bart%20van%20der%20Worp-2010-PLoS%20Med_Can%20Animal%20Models%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11306},
rating = {0}
}

@article{vanStrien:2010p11509,
author = {Tatjana van Strien and Carmen S van der Zwaluw and Rutger C M E Engels},
journal = {J Psychiatr Res},
title = {Emotional eating in adolescents: A gene (SLC6A4/5-HTT) - Depressive feelings interaction analysis},
abstract = {Eating in response to distress - i.e. emotional eating - is highly prevalent in (female) adults with binge eating, but has only a very low prevalence in young children. The present study addresses the emergence of emotional eating in adolescence in relation to depressive feelings. Because a reduction of food intake is considered the biologically natural response to distress, we tested whether the a-typical stress-response of emotional eating develops in interaction with genetic vulnerability. We hypothesized that the short allele of the 5-HTTLPR polymorphism in the serotonin transporter gene, which is associated with lower serotonin activity, would moderate the relation between depressive feelings and the increase in emotional eating, particularly in females. A sample of Dutch families with two adolescents was included in a longitudinal study with a four-year follow-up. A moderator effect of 5-HTTLPR genotype on the relation between depressive feelings and the increase in emotional eating was found in both sexes in the youngest siblings (n = 286). In the older siblings (n = 298), this specific moderator effect was only found in the girls. Younger adolescents and older adolescent girls showed a higher increase in emotional eating if they carried the 5-HTTLPR short allele. This is the first study that found support for a gene x depressive feelings interaction on emergence of emotional eating in (female) adolescents.},
affiliation = {Behavioural Science Institute, Radboud University Nijmegen, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands; Institute for Gender Studies, Radboud University Nijmegen, The Netherlands.},
pages = {},
year = {2010},
month = {Apr},
language = {ENG},
date-added = {2010-05-01 17:31:58 +0200},
date-modified = {2010-05-01 17:31:58 +0200},
doi = {10.1016/j.jpsychires.2010.03.012},
pii = {S0022-3956(10)00087-7},
pmid = {20416884},
local-url = {file://localhost/Users/chl/Dropbox/Papers/van%20Strien-2010-J%20Psychiatr%20Res_Emotional%20eating%20in.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11509},
rating = {0}
}

@article{Flynn:2008p5931,
author = {Kathryn E Flynn and Carrie B Dombeck and Esi Morgan DeWitt and Kevin A Schulman and Kevin P Weinfurt},
journal = {Clin Trials},
title = {Using item banks to construct measures of patient reported outcomes in clinical trials: investigator perceptions},
abstract = {BACKGROUND: Item response theory (IRT) promises more sensitive and efficient measurement of patient-reported outcomes (PROs) than traditional approaches; however, the selection and use of PRO measures from IRT-based item banks differ from current methods of using PRO measures. PURPOSE: To anticipate barriers to the adoption of IRT item banks into clinical trials. METHODS: We conducted semistructured telephone or in-person interviews with 42 clinical researchers who published results from clinical trials in the Journal of the American Medical Association, the New England Journal of Medicine, or other leading clinical journals from July 2005 through May 2006. Interviews included a brief tutorial on IRT item banks. RESULTS: After the tutorial, 39 of 42 participants understood the novel products available from an IRT item bank, namely customized short forms and computerized adaptive testing. Most participants (38/42) thought that item banks could be useful in their clinical trials, but they mentioned several potential barriers to adoption, including economic and logistical constraints, concerns about whether item banks are better than current PRO measures, concerns about how to convince study personnel or statisticians to use item banks, concerns about FDA or sponsor acceptance, and the lack of availability of item banks validated in specific disease populations. LIMITATIONS: Selection bias might have led to more positive responses to the concept of item banks in clinical trials. CONCLUSIONS: Clinical investigators are open to a new method of PRO measurement offered in IRT item banks, but bank developers must address investigator and stakeholder concerns before widespread adoption can be expected.},
affiliation = {Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA. kathryn.flynn@duke.edu},
number = {6},
pages = {575--86},
volume = {5},
year = {2008},
month = {Jan},
language = {eng},
keywords = {Feasibility Studies, Research Design, Reproducibility of Results, Sensitivity and Specificity, Male, Outcome Assessment (Health Care), Diffusion of Innovation, Self Assessment (Psychology), Databases as Topic, Research Personnel, Clinical Trials as Topic, Attitude of Health Personnel, Humans, Female},
date-added = {2010-02-18 23:14:52 +0100},
date-modified = {2010-03-21 20:27:31 +0100},
doi = {10.1177/1740774508098414},
pii = {5/6/575},
pmid = {19029206},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5931},
rating = {4}
}

@article{Johansson:2006p8602,
author = {Maria Johansson and Maria R{\aa}stam and Eva Billstedt and Susanna Danielsson and Kerstin Str{\"o}mland and Marilyn Miller and Christopher Gillberg},
journal = {Dev Med Child Neurol},
title = {Autism spectrum disorders and underlying brain pathology in CHARGE association},
abstract = {The rate of autism spectrum disorders (ASDs) and brain abnormalities was analyzed in 31 individuals (15 males, 16 females; age range 1mo to 31y, mean age 8y 11mo) with CHARGE association, as part of a multidisciplinary study. A meticulous neuropsychiatric examination was performed, including standardized autism diagnostic interviews. Judgement regarding ASDs was impossible in three infants and three patients who were deaf and blind. Five individuals met diagnostic criteria for autism, five for an autistic-like condition, and seven for autistic traits. Brain abnormalities were indicated in almost three-quarters of examined individuals, and midline abnormalities of the forebrain in one-third. Awareness of the coexistence of CHARGE and ASDs is important in habilitation care in CHARGE. Moreover, the results indicate that a subgroup of ASDs may be associated with errors in early embryonic brain development.},
affiliation = {Department of Child and Adolescent Psychiatry, G{\"o}teborg University, Sweden. maria.johansson@pediat.gu.se},
number = {1},
pages = {40--50},
volume = {48},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Craniofacial Abnormalities, Hearing Loss, Infant: Newborn, Brain, Neuropsychological Tests, Autistic Disorder, Pregnancy, Child, Pregnancy Complications, Male, Magnetic Resonance Imaging, Autonomic Nervous System Diseases, Child Behavior Disorders, Adolescent, Adult, Heart Defects: Congenital, Humans, Tomography: X-Ray Computed, Coloboma, Child: Preschool, Female, Cognition, Abnormalities: Multiple, Infant},
date-added = {2010-03-22 00:25:21 +0100},
date-modified = {2010-03-22 00:25:21 +0100},
doi = {10.1017/S0012162206000090},
pii = {S0012162206000090},
pmid = {16359593},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Johansson-2006-Developmental%20medicine%20and%20child%20neurology_Autism%20spectrum%20diso.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8602},
rating = {0}
}

@article{Nicodemus:2005p3526,
author = {Kristin K Nicodemus and Wenlei Liu and Gary A Chase and Ya-Yu Tsai and M Daniele Fallin},
journal = {BMC Genet},
title = {Comparison of type I error for multiple test corrections in large single-nucleotide polymorphism studies using principal components versus haplotype blocking algorithms},
abstract = {ABSTRACT : Although permutation testing has been the gold standard for assessing significance levels in studies using multiple markers, it is time-consuming. A Bonferroni correction to the nominal p-value that uses the underlying pair-wise linkage disequilibrium (LD) structure among the markers to determine the number of effectively independent tests has recently been proposed. We propose using the number of independent LD blocks plus the number of independent single-nucleotide polymorphisms for correction. Using the Collaborative Study on the Genetics of Alcoholism LD data for chromosome 21, we simulated 1,000 replicates of parent-child trio data under the null hypothesis with two levels of LD: moderate and high. Assuming haplotype blocks were independent, we calculated the number of independent statistical tests using 3 haplotype blocking algorithms. We then compared the type I error rates using a principal components-based method, the three blocking methods, a traditional Bonferroni correction, and the unadjusted p-values obtained from FBAT. Under high LD conditions, the PC method and one of the blocking methods were slightly conservative, whereas the 2 other blocking methods exceeded the target type I error rate. Under conditions of moderate LD, we show that the blocking algorithm corrections are closest to the desired type I error, although still slightly conservative, with the principal components-based method being almost as conservative as the traditional Bonferroni correction.},
affiliation = {Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. knicodem@jhsph.edu.},
pages = {S78},
volume = {6 Suppl 1},
year = {2005},
month = {Dec},
language = {ENG},
date-added = {2010-01-15 15:48:51 +0100},
date-modified = {2010-01-15 15:48:52 +0100},
doi = {10.1186/1471-2156-6-S1-S78},
pii = {1471-2156-6-S1-S78},
pmid = {16451692},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Nicodemus-2005-BMC%20Genet_Comparison%20of%20type%20I.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3526},
rating = {0}
}

@article{Zhang:2010p11534,
author = {Wensheng Zhang and Kelly Robbins and Yupeng Wang and Keith Bertrand and Romdhane Rekaya},
journal = {BMC Genomics},
title = {A jackknife-like method for classification and uncertainty assessment of multi-category tumor samples using gene expression information},
abstract = {ABSTRACT: BACKGROUND: The use of gene expression profiling for the classification of human cancer tumors has been widely investigated. Previous studies were successful in distinguishing several tumor types in binary problems. As there are over a hundred types of cancers, and potentially even more subtypes, it is essential to develop multi-category methodologies for molecular classification for any meaningful practical application. RESULTS: A jackknife-based supervised learning method called paired-samples test algorithm (PST), coupled with a binary classification model based on linear regression, was proposed and applied to two well known and challenging datasets consisting of 14 (GCM dataset) and 9 (NC160 dataset) tumor types. The results showed that the proposed method improved the prediction accuracy of the test samples for the GCM dataset, especially when t-statistic was used in the primary feature selection. For the NCI60 dataset, the application of PST improved prediction accuracy when the numbers of used genes were relatively small (100 or 200). These improvements made the binary classification method more robust to the gene selection mechanism and the size of genes to be used. The overall prediction accuracies were competitive in comparison to the most accurate results obtained by several previous studies on the same datasets and with other methods. Furthermore, the relative confidence R(T) provided a unique insight into the sources of the uncertainty shown in the statistical classification and the potential variants within the same tumor type. CONCLUSION: We proposed a novel bagging method for the classification and uncertainty assessment of multi-category tumor samples using gene expression information. The strengths were demonstrated in the application to two bench datasets.},
number = {1},
pages = {273},
volume = {11},
year = {2010},
month = {Apr},
language = {ENG},
date-added = {2010-05-01 17:36:15 +0200},
date-modified = {2010-07-29 19:20:00 +0200},
doi = {10.1186/1471-2164-11-273},
pii = {1471-2164-11-273},
pmid = {20429942},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Zhang-2010-BMC%20Genomics_A%20jackknife-like%20met-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11534},
rating = {0}
}

@article{Moya:2005p14101,
author = {Tatiana Moya and Bacy Fleitlich-Bilyk and Robert Goodman and Fabiana Chamelet Nogueira and Patr{\'\i}cia Souza Focchi and Manoela Nicoletti and Vanessa Pinzon and T{\'a}ki Athan{\'a}ssios Cord{\'a}s and Francisco Lotufo Neto},
journal = {Rev Bras Psiquiatr},
title = {The Eating Disorders Section of the Development and Well-Being Assessment (DAWBA): development and validation},
abstract = {OBJECTIVE: Development and validation of the Eating Disorders Section of the Development and Well-Being Assessment (DAWBA). It is a package of questionnaires, interviews and evaluation techniques, designed to generate DSM-IV and ICD-10 based diagnoses of anorexia, bulimia nervosa and the respective partial syndromes in epidemiological studies, in subjects who are 7 to 17 years old. The parents are interviewed in all cases, as are young people aged 11 or more. METHODS: 174 girls, divided into three groups, were assessed with the Eating Disorders Section of the Development and Well-Being Assessment: 48 with eating disorders, 55 clinical controls (with depression, obsessive-compulsive disorder or gastrointestinal disease) and 71 community controls. The sensitivity, specificity and predictive values of the assessment were investigated by comparing the Development and Well-Being Assessment diagnoses with independent psychiatric diagnoses. The test-retest reliability was investigated by reapplying the measure on 55 subjects after 2 or 3 weeks. RESULTS: For the detection of any DSM-IV and ICD-10 eating disorder, the final Development and Well-Being Assessment diagnosis had a sensitivity of 100%, specificity of 94%, positive predictive value of 88%, and a negative predictive value of 100%; there was 95% agreement between the initial and repeat diagnoses (a kappa of 0.81). CONCLUSION: The Eating Disorders Section of the Development and Well-Being Assessment has suitable psychometric properties for use in clinical and epidemiological studies.},
affiliation = {Institute of Psychiatry, University of S{\~a}o Paulo, Brazil. tatimoya@uol.com.br},
number = {1},
pages = {25--31},
volume = {27},
year = {2005},
month = {Mar},
language = {eng},
keywords = {Female, Eating Disorders, Sensitivity and Specificity, Adolescent, Bulimia Nervosa, Interview: Psychological, Humans, Child, Psychiatric Status Rating Scales, Questionnaires, Anorexia Nervosa},
date-added = {2010-08-18 11:16:51 +0200},
date-modified = {2010-08-18 11:16:52 +0200},
doi = {/S1516-44462005000100008},
pii = {S1516-44462005000100008},
pmid = {15867980},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Moya-2005-Rev%20Bras%20Psiquiatr_The%20Eating%20Disorders.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14101},
rating = {0}
}

@article{Cochran:1995p4017,
author = {S D Cochran and Jan de Leeuw and V M Mays},
journal = {Journal of Consulting and Clinical Psychology},
title = {Optimal scaling of HIV-related sexual risk behaviors in ethnically diverse homosexually active men},
abstract = {As HIV-related behavioral research moves increasingly in the direction of seeking to determine predictors of high-risk sexual behavior, more efficient methods of specifying patterns are needed. Two statistical techniques, homogeneity analysis and latent class analysis, useful in scaling binary multivariate data profiles are presented. Both were used to analyze reported sexual behavior patterns in two samples of homosexually active men, one sample of 343 primarily White gay men attending an HIV workshop and one sample of 837 African American gay men recruited nationally. Results support the existence of a single, nonlinear, latent dimension underlying male homosexual behaviors consistent with HIV-related risk taking. Both statistical methods provide an efficient means to optimally scale sexual behavior patterns, a critical outcome variable in HIV-related research.},
affiliation = {Department of Psychology, California State University, Northridge 91330, USA.},
number = {2},
pages = {270--9},
volume = {63},
year = {1995},
month = {Apr},
language = {eng},
keywords = {European Continental Ancestry Group, HIV Infections, Homosexuality: Male, Adult, Aged, Cross-Cultural Comparison, African Americans, Adolescent, Middle Aged, Sexual Behavior, Health Knowledge: Attitudes: Practice, Humans, Male, Risk-Taking},
date-added = {2010-01-18 15:22:23 +0100},
date-modified = {2010-07-29 20:45:39 +0200},
pmid = {7751488},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4017},
rating = {0}
}

@article{Sullivan:2008p3822,
author = {P F Sullivan and D Lin and J-Y Tzeng and E van den Oord and D Perkins and T S Stroup and M Wagner and S Lee and F A Wright and F Zou and W Liu and A M Downing and J Lieberman and S L Close},
journal = {Mol Psychiatry},
title = {Genomewide association for schizophrenia in the CATIE study: results of stage 1},
abstract = {Little is known for certain about the genetics of schizophrenia. The advent of genomewide association has been widely anticipated as a promising means to identify reproducible DNA sequence variation associated with this important and debilitating disorder. A total of 738 cases with DSM-IV schizophrenia (all participants in the CATIE study) and 733 group-matched controls were genotyped for 492,900 single-nucleotide polymorphisms (SNPs) using the Affymetrix 500K two-chip genotyping platform plus a custom 164K fill-in chip. Following multiple quality control steps for both subjects and SNPs, logistic regression analyses were used to assess the evidence for association of all SNPs with schizophrenia. We identified a number of promising SNPs for follow-up studies, although no SNP or multimarker combination of SNPs achieved genomewide statistical significance. Although a few signals coincided with genomic regions previously implicated in schizophrenia, chance could not be excluded. These data do not provide evidence for the involvement of any genomic region with schizophrenia detectable with moderate sample size. However, a planned genomewide association study for response phenotypes and inclusion of individual phenotype and genotype data from this study in meta-analyses hold promise for eventual identification of susceptibility and protective variants.},
affiliation = {Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7264, USA. pfsulliv@med.unc.edu},
number = {6},
pages = {570--84},
volume = {13},
year = {2008},
month = {Jun},
language = {eng},
keywords = {Genetic Variation, Case-Control Studies, Genome: Human, Schizophrenia, DNA, Computational Biology, Antipsychotic Agents, Polymorphism: Single Nucleotide, Humans, Genetic Markers, National Institute of Mental Health (U.S.), Genotype, United States},
date-added = {2010-01-16 21:01:38 +0100},
date-modified = {2010-01-16 21:01:38 +0100},
doi = {10.1038/mp.2008.25},
pii = {mp200825},
pmid = {18347602},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3822},
rating = {0}
}

@article{Mislevy:1996p4260,
author = {R J Mislevy and D H Gitomer},
title = {The role of probability-based inference in an intelligent tutoring system},
year = {1996},
date-added = {2010-01-23 21:08:35 +0100},
date-modified = {2010-01-23 21:09:15 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mislevy-1996-_The%20role%20of%20probabil.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4260},
rating = {0}
}

@article{Erlodi:2006p1662,
author = {L A Erlodi},
title = {Conditonal error variance in the WISC-IV},
abstract = {Measurement error at different ability levels in the WISC-IV was studied to
empirically test the conditional error variance hypothesis. Graduate students in clinical psychology at a Midwestern university scored fictitious WISC-IV Vocabulary subtests constructed to yield actual scaled scores of 4, 10, and 16. Classical measurement theory assumes error rate will be constant across the three conditions. Modern test theories (Item Response Theory), however, predict that the precision of a measurement instrument will change as a function of the examinee's ability level. Data supported the conditional error variance hypothesis. Scorers made significantly more errors in the low- and high-ability- level conditions than they did in the average ability condition. Implications of these findings for intelligence testing are discussed.},
year = {2006},
date-added = {2010-01-08 21:55:50 +0100},
date-modified = {2010-01-08 21:57:16 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Erlodi-2006-_Conditonal%20error%20var.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1662},
rating = {0}
}

@article{Choudhury:2006p4832,
author = {Suparna Choudhury and Sarah-Jayne Blakemore and Tony Charman},
journal = {Soc Cogn Affect Neurosci},
title = {Social cognitive development during adolescence},
abstract = {Social relationships are particularly important during adolescence. In recent years, histological and MRI studies have shown that the brain is subject to considerable structural development during adolescence. Brain regions that are implicated in social cognition, including parts of prefrontal, parietal and superior temporal cortex, undergo the most pronounced and prolonged change. However, the development of social cognition during adolescence and its neural underpinnings remains poorly understood. Here, we begin by outlining how the brain changes between childhood and adulthood. We then describe findings that have emerged from behavioural and neuroimaging studies of the recognition of facial expression during adolescence. Finally, we present new data that demonstrate development of emotional perspective taking during adolescence. In this study, 112 participants, aged 8-36 years, performed a computerised task that involved taking an emotional perspective either from the participant's own point of view or from that of another person. The results showed that average difference in reaction time (RT) to answer questions in the first person perspective (1PP) and third person perspective (3PP) significantly decreased with age. The RT difference of adults tended to cluster close to the zero line (3PP = 1PP), while a greater proportion of pre-adolescents had higher difference values in both the positive (3PP > 1PP) and negative direction (1PP > 3PP) of the scale. The data suggest that the efficiency, and possibly strategy, of perspective taking develop in parallel with brain maturation and psychosocial development during adolescence.},
affiliation = {Behavioural {\&} Brain Sciences, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH and Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK.},
number = {3},
pages = {165--174},
volume = {1},
year = {2006},
month = {Dec},
language = {ENG},
date-added = {2010-02-01 20:21:57 +0100},
date-modified = {2010-02-01 20:21:57 +0100},
doi = {10.1093/scan/nsl024},
pmid = {18985103},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4832},
rating = {0}
}

@article{Bullock:2010p12804,
author = {W Bullock and K Imai and J N Shapiro},
title = {Measuring Political Support and Issue Ownership Using Endorsement Experiments, with Application to Militant Groups in Pakistan},
abstract = {To measure the levels of support for political actors (e.g., candidates and parties) and the strength of their issue ownership, survey experiments are often conducted in which respondents are asked to express their opinion about a particular policy endorsed by a randomly selected po- litical actor. These responses are contrasted with those from a control group that receives no endorsement. This survey methodology is particularly useful for studying sensitive political atti- tudes. We develop a Bayesian hierarchical measurement model for such endorsement experiments, demonstrate its statistical properties through simulations, and use it to measure support for Is- lamist militant groups in Pakistan. Our model uses item response theory to estimate support levels on the same scale as the ideal points of respondents. The model also estimates the strength of political actors' issue ownership for specific policies as well as the relationship between respon- dents' characteristics and support levels. Our analysis of a recent survey experiment in Pakistan reveals three key patterns. First, citizens' attitudes towards militant groups are geographically clustered. Second, once these regional differences are taken into account, respondents' character- istics have little predictive power for their support levels. Finally, militant groups tend to receive less support in the areas where they operate.},
year = {2010},
date-added = {2010-06-18 22:48:47 +0200},
date-modified = {2010-06-18 22:49:24 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bullock-2010-_Measuring%20Political.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12804},
rating = {0}
}

@article{Draney:2008p2590,
author = {K Draney and M Wilson},
journal = {Psychology Science Quarterly},
title = {A LLTM approach to the examination of teachers' ratings of classroom assessment tasks},
abstract = {This paper investigates the use of a specific case of the Linear Logistic Test Model, known as the rating scale rater model, in which the item parameter is conceptualized to include an item difficulty parameter, plus a rating severity parameter. Using this model, the severity of groups of teachers is investigated when they scored sets of 321 pretests and posttests designed to be congruent with an em- bedded assessment system. The items were included in a linked design involving multiple booklets randomly allocated to students. Individual teachers were found to differ in overall severity, but also showed a reasonable amount of consistency within two of the three district moderation groups. Teach- ers also showed some mean differences between districts. There is also evidence that the model may be too tightly constrained, and further exploration using a less constrained model is indicated.},
number = {3},
pages = {417--432},
volume = {50},
year = {2008},
keywords = {teacher effects, IRT, rater effects, LLTM},
date-added = {2010-01-12 22:34:41 +0100},
date-modified = {2010-01-12 22:35:42 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Draney-2008-Psychology%20Science%20Quarterly_A%20LLTM%20approach%20to%20t.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2590},
rating = {0}
}

@article{EspositoSmythers:2009p9645,
author = {Christianne Esposito-Smythers and Anthony Spirito and Christie Rizzo and John E McGeary and Valerie S Knopik},
journal = {Pharmacol Biochem Behav},
title = {Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents},
abstract = {BACKGROUND: The A1 allele of the TaqIA polymorphism (rs1800497) in the dopamine D2 receptor gene (DRD2) has been associated with substance use. It is unclear whether this allele is a marker for an underlying propensity for specifically developing a substance use disorder, or more generally to developing an externalizing psychiatric disorder highly correlated with substance use. It is also possible that DRD2 is related to a behavioral phenotype common to externalizing disorders and substance use. METHOD: Data was obtained from 104 psychiatrically hospitalized adolescents in a larger assessment study. Adolescents were genotyped for the DRD2 TaqIA site, grouped as carriers of the A1 allele (A1+) or homozygous for the A2 allelle (A1-). Associations of the presence of the A1 allele with externalizing disorders, the intermediate phenotype of impulsivity, and measures of alcohol and drug use were examined. RESULTS: A diagnosis of conduct disorder and impulsive behavior were both associated with severity of problem drinking and/or drug use. Further, interaction effects were found between the DRD2 TaqIA polymorphism and conduct disorder (trend level) as well as A1+ status and impulsivity, such that adolescents who were carriers of the A1 allele, and had conduct disorder or impulsive behavior, reported higher levels of problematic alcohol use than those who were non-carriers (A2/A2 or A1-). The same interaction effect between this polymorphism and impulsivity was found for severity of problem drug use. In contrast, no interaction effects were found between the DRD2 allele status and ADHD on severity of problem drinking or drug use. DISCUSSION: These results suggest that the well documented relationship between conduct disorder, the behavioral phenotype of impulsivity, and problematic alcohol/drug use among adolescents may be moderated by A1 carrier status of the DRD2 gene.},
affiliation = {Center for Alcohol and Addiction Studies, Brown University, United States.},
note = {genim},
number = {3},
pages = {306--12},
volume = {93},
year = {2009},
month = {Sep},
language = {eng},
keywords = {Heterozygote, Alleles, Psychiatric Status Rating Scales, DNA, Genotype, Inpatients, Male, Adolescent, Polymorphism: Genetic, Regression Analysis, Gene Frequency, Alcoholism, Female, Conduct Disorder, Humans, Impulsive Behavior, Neuropsychological Tests, Receptors: Dopamine D2, Substance-Related Disorders},
date-added = {2010-03-25 14:53:18 +0100},
date-modified = {2010-07-29 19:43:17 +0200},
doi = {10.1016/j.pbb.2009.03.012},
pii = {S0091-3057(09)00101-4},
pmid = {19344737},
URL = {http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0N-4VYXMG3-1&_user=2432700&_coverDate=09%252F30%252F2009&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000057263&_version=1&_urlVersion=0&_userid=2432700&md5=b3462538af4c71f9a51144315b32242d},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Esposito-Smythers-2009-Pharmacol%20Biochem%20Behav_Associations%20of%20the.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9645},
rating = {0}
}

@article{Cho:2009p10273,
author = {Seung Bin Cho and Phillip K Wood and Andrew C Heath},
journal = {Behav Genet},
title = {Decomposing group differences of latent means of ordered categorical variables within a genetic factor model},
abstract = {A genetic factor model is introduced for decomposition of group differences of the means of phenotypic behavior as well as individual differences when the research variables under consideration are ordered categorical. The model employs the general Genetic Factor Model proposed by Neale and Cardon (Methodology for genetic studies of twins and families, 1992) and, more specifically, the extension proposed by Dolan et al. (Behav Genet 22: 319-335, 1992) which enables decomposition of group differences of the means associated with genetic and environmental factors. Using a latent response variable (LRV) formulation (Muth{\'e}n and Asparouhov, Latent variable analysis with categorical outcomes: multiple-group and growth modeling in Mplus. Mplus web notes: No. 4, Version 5, 2002), proportional differences of response categories between groups are modeled within the genetic factor model in terms of the distributional differences of latent response variables assumed to underlie the observed ordered categorical variables. Use of the proposed model is illustrated using a measure of conservatism in the data collected from the Australian Twin Registry.},
affiliation = {Psychological Sciences, University of Missouri, 200 South 7th Street, Psychology Building, Columbia, MO 65211, USA. sbcht3@mizzou.edu},
number = {1},
pages = {101--22},
volume = {39},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Environment, Population Groups, Models: Genetic, Phenotype, Twins, Genetics: Behavioral, Analysis of Variance, Normal Distribution, Genetic Variation, Registries, Humans, Reproducibility of Results},
date-added = {2010-04-02 15:42:00 +0200},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-008-9237-9},
pmid = {19009342},
URL = {http://www.springerlink.com/content/823885j2135170l3/},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Cho-2009-Behav%20Genet_Decomposing%20group%20di.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10273},
rating = {0}
}

@article{Mazor:1995,
author = {Kathleen M Mazor and Anil Kanjee and Brian E Clauser},
journal = {Journal of Educational Measurement},
title = {Using logistic regression and the Mantel-Haenszel with multiple ability estimates to detect Differential Item Functioning},
number = {2},
pages = {131--144},
volume = {32},
year = {1995},
date-added = {2010-01-10 11:33:24 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1981},
rating = {0}
}

@article{Knuth:1984p10909,
author = {D E Knuth},
journal = {The Computer Journal},
title = {Literate Programming},
number = {2},
pages = {97--111},
volume = {27},
year = {1984},
date-added = {2010-04-11 21:28:01 +0200},
date-modified = {2010-04-11 21:36:09 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Knuth-1984-The%20Computer%20Journal_Literate%20Programming.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10909},
rating = {0}
}

@article{Hutz:2008p3785,
author = {Janna E Hutz and Aldi T Kraja and Howard L McLeod and Michael A Province},
journal = {Genet Epidemiol},
title = {CANDID: a flexible method for prioritizing candidate genes for complex human traits},
abstract = {Genomewide studies and localized candidate gene approaches have become everyday study designs for identifying polymorphisms in genes that influence complex human traits. Yet, in general, the number of significant findings and the need to focus on smaller regions require a prioritization of genes for further study. Some candidate gene identification algorithms have been proposed in recent years to attempt to streamline this prioritization, but many suffer from limitations imposed by the source data or are difficult to use and understand. CANDID is a prioritization algorithm designed to produce impartial, accurate rankings of candidate genes that influence complex human traits. CANDID can use information from publications, protein domain descriptions, cross-species conservation measures, gene expression profiles and protein-protein interactions in its analysis. Additionally, users may supplement these data sources with results from linkage, association and other studies. CANDID was tested on well-known complex trait genes using data from the Online Mendelian Inheritance in Man database. Additionally, CANDID was evaluated in a modeled gene discovery environment, where it ranked genes whose trait associations were published after CANDID's databases were compiled. In all settings, CANDID exhibited high sensitivity and specificity, indicating an improvement upon previously published algorithms. Its accuracy and ease of use make CANDID a highly useful tool in study design and analysis for complex human traits.},
affiliation = {Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, Missouri, USA. jehutz@artsci.wustl.edu},
number = {8},
pages = {779--90},
volume = {32},
year = {2008},
month = {Dec},
language = {eng},
keywords = {Databases: Genetic, Algorithms, Genome: Human, Genetic Techniques, Genetic Diseases: Inborn, Gene Expression Profiling, Models: Genetic, Computational Biology, Models: Statistical, Protein Structure: Tertiary, Humans, Male, ROC Curve, Linkage (Genetics), Female},
date-added = {2010-01-16 21:00:41 +0100},
date-modified = {2010-01-16 21:00:42 +0100},
doi = {10.1002/gepi.20346},
pmid = {18613097},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3785},
rating = {0}
}

@article{Knodel:2001p7749,
author = {J Knodel and M VanLandingham and C Saengtienchai and W Im-em},
journal = {Soc Sci Med},
title = {Older people and AIDS: quantitative evidence of the impact in Thailand},
abstract = {Discussions of the AIDS epidemic rarely consider the impact on older people except as infected persons. Virtually no systematic quantitative assessments exist of the involvement of parents or other older generation relatives in the living and caretaking arrangements of persons with AIDS in either the West or the developing world. We assess the extent of such types of involvement in Thailand, a country where substantial proportions of elderly parents depend on adult children for support and where co-residence with an adult child is common. Interviews with local key informants in the public health system in rural and urban communities provided quantitative information on a total of 963 adult cases who either had died of AIDS or were currently symptomatic. The results indicate that a substantial proportion of persons with AIDS move back to their communities of origin at some stage of the illness. Two-thirds of the adults who died of an AIDS-related disease either lived with or adjacent to a parent by the terminal stage of illness and a parent, usually the mother, acted as a main caregiver for about half. For 70%, either a parent or other older generation relative provided at least some care. The vast majority of the parents were aged 50 or more and many were aged 60 or older. This extent of older generation involvement appears to be far greater than in Western countries such as the US. We interpret the difference as reflecting the contrasting epidemiological and socio-cultural situations in Thailand and the West. The fact that older people in Thailand, and probably many other developing countries, are extensively impacted by the AIDS epidemic through their involvement with their infected adult children has important implications for public health programs that address caretaker education and social and economic support.},
affiliation = {Population Studies Center and Department of Sociology, Institute for Social Research, University of Michigan, Ann Arbor 48106-1248, USA. jknodel@umich.edu},
number = {9},
pages = {1313--27},
volume = {52},
year = {2001},
month = {May},
language = {eng},
keywords = {Family Characteristics, Thailand, Adolescent, Aged, Developing Countries, Middle Aged, Risk Factors, Aged: 80 and over, Acquired Immunodeficiency Syndrome, Female, Interviews as Topic, Caregivers, Adult, Parents, Social Support, Humans, HIV Infections, Male, Home Nursing, Intergenerational Relations},
date-added = {2010-03-17 20:50:46 +0100},
date-modified = {2010-03-17 20:50:46 +0100},
pii = {S0277953600002331},
pmid = {11286358},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7749},
rating = {0}
}

@article{Laudadio:2005p1573,
author = {Teresa Laudadio and Pieter Pels and Lieven De Lathauwer and Paul Van Hecke and Sabine Van Huffel},
journal = {Magn Reson Med},
title = {Tissue segmentation and classification of MRSI data using canonical correlation analysis},
abstract = {In this article an accurate and efficient technique for tissue typing is presented. The proposed technique is based on Canonical Correlation Analysis, a statistical method able to simultaneously exploit the spectral and spatial information characterizing the Magnetic Resonance Spectroscopic Imaging (MRSI) data. Recently, Canonical Correlation Analysis has been successfully applied to other types of biomedical data, such as functional MRI data. Here, Canonical Correlation Analysis is adapted for MRSI data processing in order to retrieve in an accurate and efficient way the possible tissue types that characterize the organ under investigation. The potential and limitations of the new technique have been investigated by using simulated as well as in vivo prostate MRSI data, and extensive studies demonstrate a high accuracy, robustness, and efficiency. Moreover, the performance of Canonical Correlation Analysis has been compared to that of ordinary correlation analysis. The test results show that Canonical Correlation Analysis performs best in terms of accuracy and robustness.},
affiliation = {Department of Electrical Engineering, Division ESAT-SCD, Katholieke Universiteit Leuven, Leuven-Heverlee, Belgium. laudadio@esat.kuleuven.ac.be},
number = {6},
pages = {1519--29},
volume = {54},
year = {2005},
month = {Dec},
language = {eng},
keywords = {Phantoms: Imaging, Pattern Recognition: Automated, Image Interpretation: Computer-Assisted, Magnetic Resonance Spectroscopy, Algorithms, Prostatic Neoplasms, Artificial Intelligence, Information Storage and Retrieval, Male, Humans, Image Enhancement, Imaging: Three-Dimensional, Magnetic Resonance Imaging, Reproducibility of Results, Sensitivity and Specificity, Statistics as Topic},
date-added = {2010-01-07 16:59:26 +0100},
date-modified = {2010-01-07 16:59:26 +0100},
doi = {10.1002/mrm.20710},
pmid = {16276498},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Laudadio-2005-Magn%20Reson%20Med_Tissue%20segmentation.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1573},
rating = {0}
}

@article{Harvey:2003p1810,
author = {R J Harvey},
journal = {Annual Conference of the Society for Industrial and Organizational Psychology},
title = {Applicability of Binary IRT Models to Job Analysis Data},
abstract = {Item response theory (IRT) is increasingly being used in applied assessment, offering many benefits in comparison to classical test theory techniques. However, the question of whether IRT will prove useful with respect to assessing general work activity (GWA) constructs in job and occupational analysis (JOA) has received little attention. This study reviewed several potential concerns and benefits regarding the use of IRT in JOA, and examined the performance of binary IRT models using moderate-specificity data from the Common-Metric Questionnaire (CMQ; Harvey, 1991b), abstract ratings from the Occupational Information Network (O*NET) GWA survey, and Monte Carlo tests of the effectiveness of IRT appropriateness indices for detecting aberrant profiles Results indicated that IRT may be highly useful in JOA, especially in view of the importance of detecting careless or distorted JOA ratings.},
year = {2003},
date-added = {2010-01-09 21:52:55 +0100},
date-modified = {2010-01-09 21:53:33 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Harvey-2003-Annual%20Conference%20of%20the%20Society%20for%20Industrial%20and%20Organizational%20Psychology_Applicability%20of%20Bin.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1810},
rating = {0}
}

@article{Baumeister:2002p3414,
author = {J Baumeister and D Seipel},
journal = {Proceedings of the 13th. International Workshop on Principles of Diagnosis},
title = {Diagnostic Reasoning with Multilevel Set-Covering Models},
abstract = {We consider multilevel set-covering models for diagnos- tic reasoning: though a lot of work has been done in this field, knowl- edge acquisition efforts have been investigated only insufficiently. We will show how set-covering models can be build incrementally and how they can be refined by knowledge enhancements or repre- sentational extensions. All these extensions have a primary charac- teristic: they can be applied without changing the basic semantics of the model.},
year = {2002},
date-added = {2010-01-15 14:49:37 +0100},
date-modified = {2010-01-15 14:51:45 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Baumeister-2002-Proceedings%20of%20the%2013th.%20International%20Workshop%20on%20Principles%20of%20Diagnosis_Diagnostic%20Reasoning.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3414},
rating = {0}
}

@article{Orlando:2004p2728,
author = {M Orlando},
title = {Critical Issues to Address when Applying Item Response Theory (IRT) Models},
year = {2004},
date-added = {2010-01-13 14:18:22 +0100},
date-modified = {2010-01-13 14:19:28 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Orlando-2004-_Critical%20Issues%20to%20A.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2728},
rating = {0}
}

@article{Boschen:2006p4876,
author = {Mark J Boschen and Tian P S Oei},
journal = {Aust N Z J Psychiatry},
title = {Factor structure of the Mood and Anxiety Symptom Questionnaire does not generalize to an anxious/depressed sample},
abstract = {OBJECTIVE: The tripartite model of anxiety and depression has been proposed as a representation of the structure of anxiety and depression symptoms. The Mood and Anxiety Symptom Questionnaire (MASQ) has been put forwards as a valid measure of the tripartite model of anxiety and depression symptoms. This research set out to examine the factor structure of anxiety and depression symptoms in a clinical sample to assess the MASQ's validity for use in this population. METHOD: The present study uses confirmatory factor analytic methods to examine the psychometric properties of the MASQ in 470 outpatients with anxiety and mood disorder. RESULTS: The results showed that none of the previously reported two-factor, three-factor or five-factor models adequately fit the data, irrespective of whether items or subscales were used as the unit of analysis. CONCLUSION: It was concluded that the factor structure of the MASQ in a mixed anxiety/depression clinical sample does not support a structure consistent with the tripartite model. This suggests that researchers using the MASQ with anxious/depressed individuals should be mindful of the instrument's psychometric limitations.},
affiliation = {School of Psychology, Griffith University, Gold Coast, Queensland, Australia. m.boschen@griffith.edu.au},
number = {11-12},
pages = {1016--24},
volume = {40},
year = {2006},
month = {Jan},
language = {eng},
keywords = {Comorbidity, Personality Inventory, Adolescent, Depressive Disorder, Anxiety Disorders, Models: Statistical, Aged, Female, Middle Aged, Reproducibility of Results, Adult, Humans, Factor Analysis: Statistical, Male, Psychometrics, Questionnaires},
date-added = {2010-02-01 20:30:47 +0100},
date-modified = {2010-02-01 20:30:47 +0100},
doi = {10.1111/j.1440-1614.2006.01926.x},
pii = {ANP1926},
pmid = {17054571},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Boschen-2006-Aust%20N%20Z%20J%20Psychiatry_Factor%20structure%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4876},
rating = {0}
}

@article{Katerberg:2010p12575,
author = {Hilga Katerberg and Kevin L Delucchi and S Evelyn Stewart and Christine Lochner and Damiaan A J P Denys and Denise E Stack and J Michael Andresen and J E Grant and Suck W Kim and Kyle A Williams and Johan A den Boer and Anton J L M van Balkom and Johannes H Smit and Patricia van Oppen and Annemiek Polman and Michael A Jenike and Dan J Stein and Carol A Mathews and Danielle C Cath},
journal = {Behav Genet},
title = {Symptom Dimensions in OCD: Item-Level Factor Analysis and Heritability Estimates},
abstract = {To reduce the phenotypic heterogeneity of obsessive-compulsive disorder (OCD) for genetic, clinical and translational studies, numerous factor analyses of the Yale-Brown Obsessive Compulsive Scale checklist (YBOCS-CL) have been conducted. Results of these analyses have been inconsistent, likely as a consequence of small sample sizes and variable methodologies. Furthermore, data concerning the heritability of the factors are limited. Item and category-level factor analyses of YBOCS-CL items from 1224 OCD subjects were followed by heritability analyses in 52 OCD-affected multigenerational families. Item-level analyses indicated that a five factor model: (1) taboo, (2) contamination/cleaning, (3) doubts, (4) superstitions/rituals, and (5) symmetry/hoarding provided the best fit, followed by a one-factor solution. All 5 factors as well as the one-factor solution were found to be heritable. Bivariate analyses indicated that the taboo and doubts factor, and the contamination and symmetry/hoarding factor share genetic influences. Contamination and symmetry/hoarding show shared genetic variance with symptom severity. Nearly all factors showed shared environmental variance with each other and with symptom severity. These results support the utility of both OCD diagnosis and symptom dimensions in genetic research and clinical contexts. Both shared and unique genetic influences underlie susceptibility to OCD and its symptom dimensions.},
affiliation = {Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.},
pages = {},
year = {2010},
month = {Apr},
language = {ENG},
date-added = {2010-06-15 22:25:57 +0200},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-010-9339-z},
pmid = {20361247},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Katerberg-2010-Behav%20Genet_Symptom%20Dimensions%20i.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12575},
rating = {5}
}

@article{Wicherts:2010p13784,
author = {J M Wicherts and C V Dolan},
journal = {Educational Measurement: Issues {\&} Practice},
title = {Measurement invariance in confirmatory factor analysis; An illustration using IQ test performance of minorities},
abstract = {Measurement invariance with respect to groups is an essential aspect of the fair use of scores
of intelligence tests and other psychological measurements. It widely believed that equal factor loadings are sufficient to establish measurement invariance in confirmatory factor analysis. Here, it is shown why establishing measurement invariance with confirmatory factor analysis requires a statistical test of the equality over groups of measurement intercepts. Without this essential test, measurement bias may be overlooked. A re-analysis of a study by J. Te Nijenhuis, E. Tolboom, W. Resing, and N. Bleichrodt (2004) on ethnic differences on the RAKIT IQ test illustrates that ignoring intercept differences may lead to the conclusion that bias of IQ tests with respect to minorities is small, while in reality bias is quite severe.},
year = {2010},
date-added = {2010-07-29 12:14:51 +0200},
date-modified = {2010-07-29 12:15:45 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wicherts-2010-Educational%20Measurement%20Issues%20&%20Practice_Measurement%20invarian.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13784},
rating = {0}
}

@article{Murray:2008p6409,
author = {David M Murray and Sherri L Pals and Jonathan L Blitstein and Catherine M Alfano and Jennifer Lehman},
journal = {Journal of The National Cancer Institute},
title = {Design and analysis of group-randomized trials in cancer: a review of current practices},
abstract = {BACKGROUND: Previous reviews have identified problems in the design and analysis of group-randomized trials in a number of areas. Similar problems may exist in cancer research, but there have been no comprehensive reviews. METHODS: We searched Medline and PubMed for group-randomized trials focused on cancer prevention and control that were published between 2002 and 2006. We located and reviewed 75 articles to determine whether articles included evidence of taking group randomization into account in establishing the size of the trial, such as reporting the expected intraclass correlation, the group component of variance, or the variance inflation factor. We also examined the analytical approaches to determine their appropriateness. RESULTS: Only 18 (24%) of the 75 articles documented appropriate methods for sample size calculations. Only 34 (45%) limited their reports to analyses judged to be appropriate. Fully 26 (34%) failed to report any analyses that were judged to be appropriate. The most commonly used inappropriate analysis was an analysis at the individual level that ignored the groups altogether. Nine articles (12%) did not provide sufficient information. CONCLUSIONS: Many investigators who use group-randomized trials in cancer research do not adequately attend to the special design and analytic challenges associated with these trials. Failure to do so can lead to reporting type I errors as real effects, mislead investigators and policy-makers, and slow progress toward control and prevention of cancer. A collaborative effort by investigators, statisticians, and others will be required to ensure that group-randomized trials are planned and analyzed using appropriate methods so that the scientific community can have confidence in the published results.},
affiliation = {Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, USA. dmurray@cph.osu.edu},
number = {7},
pages = {483--91},
volume = {100},
year = {2008},
month = {Apr},
language = {eng},
keywords = {Research Design, Randomized Controlled Trials as Topic, Humans, Neoplasms},
date-added = {2010-02-23 08:26:38 +0100},
date-modified = {2010-02-23 08:26:39 +0100},
doi = {10.1093/jnci/djn066},
pii = {djn066},
pmid = {18364501},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6409},
rating = {0}
}

@article{Boulesteix:2008p2566,
author = {A-L Boulesteix and C Strobl and T Augustin and M Daumer},
journal = {Cancer informatics},
title = {Evaluating Microarray-based Classifiers: An Overview},
abstract = {For the last eight years, microarray-based class prediction has been the

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