text:
. shuangge.ma@yale.edu},
pages = {60},
volume = {8},
year = {2007},
month = {Jan},
language = {eng},
keywords = {Tumor Markers: Biological, Gene Expression Profiling, Cluster Analysis, Humans, Neoplasm Proteins, Algorithms, Neoplasms, Oligonucleotide Array Sequence Analysis, Multigene Family, Artificial Intelligence, Pattern Recognition: Automated},
date-added = {2010-02-17 21:07:47 +0100},
date-modified = {2010-02-17 21:07:47 +0100},
doi = {10.1186/1471-2105-8-60},
pii = {1471-2105-8-60},
pmid = {17316436},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ma-2007-BMC%20Bioinformatics_Supervised%20group%20Las.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5893},
rating = {0}
}

@article{Rice:2000p7894,
author = {D Rice and S Barone},
journal = {Environ Health Perspect},
title = {Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models},
abstract = {Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes (i.e., proliferation, migration, differentiation, synaptogenesis, myelination, and apoptosis). Evidence from numerous sources demonstrates that neural development extends from the embryonic period through adolescence. In general, the sequence of events is comparable among species, although the time scales are considerably different. Developmental exposure of animals or humans to numerous agents (e.g., X-ray irradiation, methylazoxymethanol, ethanol, lead, methyl mercury, or chlorpyrifos) demonstrates that interference with one or more of these developmental processes can lead to developmental neurotoxicity. Different behavioral domains (e.g., sensory, motor, and various cognitive functions) are subserved by different brain areas. Although there are important differences between the rodent and human brain, analogous structures can be identified. Moreover, the ontogeny of specific behaviors can be used to draw inferences regarding the maturation of specific brain structures or neural circuits in rodents and primates, including humans. Furthermore, various clinical disorders in humans (e.g., schizophrenia, dyslexia, epilepsy, and autism) may also be the result of interference with normal ontogeny of developmental processes in the nervous system. Of critical concern is the possibility that developmental exposure to neurotoxicants may result in an acceleration of age-related decline in function. This concern is compounded by the fact that developmental neurotoxicity that results in small effects can have a profound societal impact when amortized across the entire population and across the life span of humans.},
affiliation = {National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, D.C., USA.},
pages = {511--33},
volume = {108 Suppl 3},
year = {2000},
month = {Jun},
language = {eng},
keywords = {Pregnancy, Embryonic and Fetal Development, Humans, Time Factors, Nervous System, Neurotoxins, Primates, Female, Infant, Child: Preschool, Rats, Infant: Newborn, Neuronal Plasticity, Cell Movement, Apoptosis, Adult, Middle Aged, Xenobiotics, Animals, Child, Aging, Cell Differentiation, Aged, Mice},
date-added = {2010-03-20 19:19:39 +0100},
date-modified = {2010-03-20 19:19:39 +0100},
pii = {sc271_5_1835},
pmid = {10852851},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Rice-2000-Environ%20Health%20Perspect_Critical%20periods%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7894},
rating = {0}
}

@article{Mogg:2007p10196,
author = {Karin Mogg and Matthew Garner and Brendan P Bradley},
journal = {Biol Psychol},
title = {Anxiety and orienting of gaze to angry and fearful faces},
abstract = {Neuroscience research indicates that individual differences in anxiety may be attributable to a neural system for threat-processing, involving the amygdala, which modulates attentional vigilance, and which is more sensitive to fearful than angry faces. Complementary cognitive studies indicate that high-anxious individuals show enhanced visuospatial orienting towards angry faces, but it is unclear whether fearful faces elicit a similar attentional bias. This study compared biases in initial orienting of gaze to fearful and angry faces, which varied in emotional intensity, in high- and low-anxious individuals. Gaze was monitored whilst participants viewed a series of face-pairs. Results showed that fearful and angry faces elicited similar attentional biases. High-anxious individuals were more likely to direct gaze at intense negative facial expressions, than low-anxious individuals, whereas the groups did not differ in orienting to mild negative expressions. Implications of the findings for research into the neural and cognitive bases of emotion processing are discussed.},
affiliation = {School of Psychology, University of Southampton, Highfield, Southampton, UK. kmogg@soton.ac.uk},
number = {3},
pages = {163--9},
volume = {76},
year = {2007},
month = {Oct},
language = {eng},
keywords = {Anger, Adult, Fear, Female, Fixation: Ocular, Humans, Pattern Recognition: Visual, Adolescent, Reaction Time, Facial Expression, Anxiety, Male, Analysis of Variance, Attention},
date-added = {2010-04-01 18:17:24 +0200},
date-modified = {2010-04-01 18:17:24 +0200},
doi = {10.1016/j.biopsycho.2007.07.005},
pii = {S0301-0511(07)00119-6},
pmid = {17764810},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Mogg-2007-Biol%20Psychol_Anxiety%20and%20orientin.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10196},
rating = {0}
}

@inbook{Martin:1983,
author = {E Martin},
journal = {Book},
title = {Handbook of survey research},
chapter = {Surveys as social indicators: Problems in monitoring trends},
year = {1983},
date-added = {2010-01-03 19:34:17 +0100},
date-modified = {2010-07-29 19:21:41 +0200},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p980},
rating = {0}
}

@article{Jones:2009p5387,
author = {James F Jones and Jin-Mann S Lin and Elizabeth M Maloney and Roumiana S Boneva and Urs M Nater and Elizabeth R Unger and William C Reeves},
journal = {BMC Med},
title = {An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome},
abstract = {BACKGROUND: The diagnosis of chronic fatigue syndrome (CFS) in research studies requires the exclusion of subjects with medical and psychiatric conditions that could confound the analysis and interpretation of results. This study compares illness parameters between individuals with CFS who have and those who do not have exclusionary conditions. METHODS: We used a population-based telephone survey of randomly selected individuals, followed by a clinical evaluation in the study metropolitan, urban, and rural counties of Georgia, USA. The medical and psychiatric histories of the subjects were examined and they underwent physical and psychiatric examinations and laboratory screening. We also employed the multidimensional fatigue inventory (MFI), the medical outcomes survey short form-36 (SF-36) and the US Centres for Disease Control and Prevention symptom inventory (SI). RESULTS: Twenty-nine percent (1,609) of the 5623 subjects who completed the detailed telephone interview reported exclusionary diagnoses and we diagnosed an exclusionary condition in 36% of 781 clinically evaluated subjects. Both medical and psychiatric exclusionary conditions were more common in women, blacks and participants from rural areas. Subjects with and without exclusions had similar levels of fatigue and impairment as measured by the MFI and SF-36; those with CFS-like illness (not meeting the formal CFS definition) were more likely to have an exclusionary diagnosis. After adjusting for demographics, body mass index, fatigue subscales, SF-36 subscales and CFS symptoms, CFS-like illness did not remain significantly associated with having an exclusionary diagnosis. CONCLUSION: Medical and psychiatric illnesses associated with fatigue are common among the unwell. Those who fulfill CFS-like criteria need to be evaluated for potentially treatable conditions. Those with exclusionary conditions are equally impaired as those without exclusions.},
affiliation = {Chronic Viral Diseases Branch, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A15, Atlanta, GA 30333, USA. jaj9@cdc.gov},
pages = {57},
volume = {7},
year = {2009},
month = {Jan},
language = {eng},
keywords = {Biomedical Research, Adult, Random Allocation, Adolescent, Humans, Fatigue Syndrome: Chronic, Confounding Factors (Epidemiology), Male, Comorbidity, Interviews as Topic, Young Adult, Georgia, Middle Aged, Patient Selection, Female},
date-added = {2010-02-11 10:35:00 +0100},
date-modified = {2010-07-29 19:20:21 +0200},
doi = {10.1186/1741-7015-7-57},
pii = {1741-7015-7-57},
pmid = {19818157},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Jones-2009-BMC%20Med_An%20evaluation%20of%20exc.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5387},
rating = {0}
}

@article{Shoemaker:1999p7182,
author = {J S Shoemaker and I S Painter and B S Weir},
journal = {Trends Genet},
title = {Bayesian statistics in genetics: a guide for the uninitiated},
abstract = {Statistical analyses are used in many fields of genetic research. Most geneticists are taught classical statistics, which includes hypothesis testing, estimation and the construction of confidence intervals; this framework has proved more than satisfactory in many ways. What does a Bayesian framework have to offer geneticists? Its utility lies in offering a more direct approach to some questions and the incorporation of prior information. It can also provide a more straightforward interpretation of results. The utility of a Bayesian perspective, especially for complex problems, is becoming increasingly clear to the statistics community; geneticists are also finding this framework useful and are increasingly utilizing the power of this approach.},
affiliation = {The Cancer Prevention, Detection, Control Research Program, Duke Medical Center, Box 2949, Durham, NC 27710, USA. shoem003@mc.duke.edu},
number = {9},
pages = {354--8},
volume = {15},
year = {1999},
month = {Sep},
language = {eng},
keywords = {Models: Genetic, Quantitative Trait: Heritable, Biometry, Probability, Genetics, Bayes Theorem},
date-added = {2010-03-06 20:32:49 +0100},
date-modified = {2010-07-29 19:54:35 +0200},
pii = {S0168-9525(99)01751-5},
pmid = {10461203},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7182},
rating = {0}
}

@article{deStavola:2008p421,
author = {BL de Stavola and D R Cox},
journal = {Biometrika},
title = {On the consequences of overstratification},
abstract = {It is common, in particular in observational studies in epidemiology, to impose stratification to adjust for possible effects of age and other variables on the binary outcome of interest. Overstratification may lower the precision of the estimated effects of interest. Understratification risks bias. These issues are studied analytically. Asymptotic results show that loss of efficiency depends on the true effect and on a measure of the average imbalance across strata between exposed and unexposed individuals. Bias depends on the correlation between stratum-specific size imbalances and event rates in the unexposed. Approximate results are also given. An example is used.},
affiliation = {London School of Hygiene and Tropical Medicine, London WC1E 7HT, U.K.},
number = {4},
pages = {992--996},
volume = {95},
year = {2008},
keywords = {Epidemiology, Logistic model, Confounder, Bias, Matched pairs, Poisson distribution, Conditional likelihood, Information},
date-added = {2010-01-03 12:16:20 +0100},
date-modified = {2010-01-03 12:19:05 +0100},
doi = {10.1093/biomet/asn039},
local-url = {file://localhost/Users/chl/Dropbox/Papers/de%20Stavola-2008-Biometrika_On%20the%20consequences.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p421},
rating = {0}
}

@article{Mojs:2007p6024,
author = {Ewa Mojs and Ewa Gajewska and W{\l}odzimierz Samborski},
journal = {Ann Acad Med Stetin},
title = {[Diagnostic and therapeutic problems in children with West syndrom]},
abstract = {West syndrome is a kind of epileptic encephalopathy causing many different psychomotor disturbances--feet and hand movements, cognitive dysfunctions and mental retardation. Psychomotor retardation and other cognitive deficits occur in 80-85% of children with West syndrome. There are two clinical forms of the syndrome distinguished-- mild and severe disease. Good control of seizures is one of the most important factors influencing the effectiveness of rehabilitation activity. Only integrated long lasting therapeutic process, demanding close cooperation of neurologists, rehabilitants and psychologists improves the effectiveness of work.},
affiliation = {Zak{\l}ad Organizacji i Zarzadzania Uniwersytetu Medycznego im. K. Marcinkowskiego ul. Smoluchowskiego 11, 60-179 Pozna{\'n}.},
number = {1},
pages = {68--71; discussion 71},
volume = {53},
year = {2007},
month = {Jan},
language = {pol},
keywords = {Spasms: Infantile, Child, Infant, Infant: Newborn, Humans, Social Environment, Family Characteristics},
date-added = {2010-02-19 16:59:04 +0100},
date-modified = {2010-02-19 16:59:04 +0100},
pmid = {18561613},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6024},
rating = {0}
}

@article{Wyrwich:2003p7448,
author = {Kathleen W Wyrwich and Harold S Nelson and William M Tierney and Ajit N Babu and Kurt Kroenke and Fredric D Wolinsky},
journal = {Ann Allergy Asthma Immunol},
title = {Clinically important differences in health-related quality of life for patients with asthma: an expert consensus panel report},
abstract = {BACKGROUND: Standards for change in health-related quality of life (HRQoL) measures used among asthmatic patients have been established by considering only patient preferences to determine important differences and may not reflect an informed clinical evaluation of change. OBJECTIVE: To establish clinically important difference (CID) standards through the consensus of an expert physician panel for the Juniper Asthma Quality of Life Questionnaire (AQLQ) and Medical Outcomes Study Short-Form 36-Item Health Survey (SF-36, version 2) when used to measure HRQoL among asthmatic patients. METHODS: We organized an 8-person panel of physicians familiar with measuring HRQoL among asthmatic patients with the AQLQ and the SF-36. This expert panel participated in 2 rounds of a modified Delphi process before attending an in-person consensus meeting to establish the CID standards for small, moderate, and large changes in the AQLQ and the SF-36. After the consensus meeting, the panel used an iterative improvement process to cooperatively complete their final report. RESULTS: The expert panel's thresholds for detecting CIDs in the domains of the AQLQ were much higher than previously established levels using patient-perceived changes. CIDs for asthma were also ascertained on the scales of the SF-36, version 2, which were markedly greater than previously cited cross-sectional differences between patient groups. CONCLUSIONS: The CID standards established by this expert panel elucidate a potential distinction between patient and physician perspectives of important HRQoL changes. The many stakeholders of HRQoL difference standards should consider this distinction when adopting standards to evaluate patient change.},
affiliation = {Saint Louis University Department of Research Methodology, St. Louis, Missouri, USA. wyrwichk@slu.edu},
number = {2},
pages = {148--53},
volume = {91},
year = {2003},
month = {Aug},
language = {eng},
keywords = {Questionnaires, Disease Management, Treatment Outcome, Asthma, Humans, Quality of Life},
date-added = {2010-03-10 20:40:51 +0100},
date-modified = {2010-03-10 20:40:51 +0100},
pmid = {12952108},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7448},
rating = {0}
}

@article{Frokjaer:2009p8855,
author = {Vibe G Frokjaer and Maj Vinberg and David Erritzoe and Claus Svarer and William Baar{\'e} and Esben Budtz-Joergensen and Karine Madsen and Jacob Madsen and Lars V Kessing and Gitte M Knudsen},
journal = {Neuroimage},
title = {High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding},
abstract = {Mood disorders are elicited through a combination of genetic and environmental stress factors, and treatment with selective serotonin reuptake inhibitors ameliorates depressive symptoms. Changes in the serotonin transporter (SERT) binding may therefore occur in depressive patients and in subjects at risk for developing depression. The aim of this study was to explore whether abnormalities in SERT might be present in healthy individuals with familial predisposition to mood disorder. Nine individuals at high familial risk (mean age 32.2+/-4.2 years) and 11 individuals at low risk (mean age 32.4+/-5.0 years) for developing mood disorder were included. The subjects were healthy twins with or without a co-twin history of mood disorder identified by linking information from the Danish Twin Register and the Danish Psychiatric Central Register. Regional in vivo brain serotonin transporter binding was measured with [(11)C]DASB PET. The volumes of interest included the orbitofrontal cortex, the dorsolateral prefrontal cortex, the ventrolateral prefrontal cortex, anterior cingulate, caudate, putamen, thalamus, and midbrain. We found that individuals at high familial risk for mood disorders had a 35% reduction in SERT binding in dorsolateral prefrontal cortex (p=0.014, Bonferroni corrected) and on a trend basis a 15% reduction in anterior cingulate (p=0.018, un-corrected). The depression and symptom scores of the high and the low risk individuals were not significantly different. In conclusion, our data suggest that a low SERT binding in dorsolateral prefrontal cortex represents a trait marker for mood disorders.},
affiliation = {Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Denmark. vibe@nru.dk},
number = {2},
pages = {360--6},
volume = {46},
year = {2009},
month = {Jun},
language = {eng},
keywords = {Serotonin Plasma Membrane Transport Proteins, Protein Binding, Family, Humans, Aniline Compounds, Adult, Mood Disorders, Male, Diseases in Twins, Positron-Emission Tomography, Risk Factors, Radiopharmaceuticals, Sulfides, Tissue Distribution, Prefrontal Cortex, Female},
date-added = {2010-03-22 12:39:36 +0100},
date-modified = {2010-03-22 12:39:36 +0100},
doi = {10.1016/j.neuroimage.2009.02.008},
pii = {S1053-8119(09)00145-1},
pmid = {19233297},
URL = {http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-4VNH3YB-1&_user=2432700&_coverDate=06%252F30%252F2009&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000057263&_version=1&_urlVersion=0&_userid=2432700&md5=68a281d74858eb5dc773d25e300a470b},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Frokjaer-2009-Neuroimage_High%20familial%20risk%20f.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8855},
rating = {0}
}

@article{Edwards:2010p8343,
author = {Phil Edwards},
journal = {Trials},
title = {Questionnaires in clinical trials: guidelines for optimal design and administration},
abstract = {A good questionnaire design for a clinical trial will minimise bias and maximise precision in the estimates of treatment effect within budget. Attempts to collect more data than will be analysed may risk reducing recruitment (reducing power) and increasing losses to follow-up (possibly introducing bias). The mode of administration can also impact on the cost, quality and completeness of data collected. There is good evidence for design features that improve data completeness but further research is required to evaluate strategies in clinical trials. Theory-based guidelines for style, appearance, and layout of self-administered questionnaires have been proposed but require evaluation.},
affiliation = {Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. phil.edwards@LSHTM.ac.uk},
pages = {2},
volume = {11},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-03-21 12:47:09 +0100},
date-modified = {2010-07-29 19:54:38 +0200},
doi = {10.1186/1745-6215-11-2},
pii = {1745-6215-11-2},
pmid = {20064225},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Edwards-2010-Trials_Questionnaires%20in%20cl.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p8343},
rating = {0}
}

@article{Youngstrom:2002,
author = {E A Youngstrom and K W Green},
journal = {Educational and Psychological Measurement},
title = {Reliability Generalization of self-report of emotions when using the Differential Emotions Scale},
volume = {62},
year = {2002},
date-added = {2010-01-10 11:33:21 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2068},
rating = {0}
}

@article{Scognamiglio:2007p4517,
author = {Paola Scognamiglio and Vincenzo Galati and Assunta Navarra and Maria Antonella Longo and Maria Stella Aloisi and Maria Giulia Antonini and Massimo Puoti and Piero Luigi Almasio and Giuseppe Ippolito and Enrico Girardi},
journal = {World J Gastroenterol},
title = {Impact of hepatitis C virus infection on lifestyle},
abstract = {AIM: To evaluate the impact of the diagnosis of hepatitis C infection on lifestyle habits such as smoking, drinking, sports activity and diet. METHODS: A self-administered, anonymous questionnaire was offered to out-patients with HCV infection consecutively attending three clinical centres in Italy. RESULTS: Of the 275 respondents, 62.2% (171) were male. Mean age was 51 (range 20-80) years. Overall, after the diagnosis of hepatitis C, 74.5% of drinkers had modified (giving up or reducing) alcohol consumption, 21.3% of smokers had modified their habits and 32.3% of subjects who reported sports activity had either stopped or reduced frequency of activity or chose a less fatiguing sport. Sixty-four percent of the respondents reported having modified their diet, most of them on physician's advice. CONCLUSION: After the diagnosis of hepatitis C many patients correctly modified their alcohol consumption and a minority their smoking habits. The reason for reported changes in diet and physical activity needs further investigations.},
affiliation = {Istituto Nazionale per le Malattie Infettive, L. Spallanzani IRCCS, Via Portuense 292, Roma 00149, Italy. scognamiglio@inmi.it},
number = {19},
pages = {2722--6},
volume = {13},
year = {2007},
month = {May},
language = {eng},
keywords = {Italy, Male, Alcohol Drinking, Female, Health Surveys, Sports, Aged, Humans, Smoking, Aged: 80 and over, Hepatitis C, Health Behavior, Adult, Middle Aged, Diet, Life Style},
date-added = {2010-01-29 22:10:20 +0100},
date-modified = {2010-07-29 19:55:16 +0200},
pmid = {17569142},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Scognamiglio-2007-World%20J%20Gastroenterol_Impact%20of%20hepatitis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4517},
rating = {0}
}

@article{Bosco:2010p6525,
author = {Jaclyn L F Bosco and Rebecca A Silliman and Soe Soe Thwin and Ann M Geiger and Diana S M Buist and Marianne N Prout and Marianne Ulcickas Yood and Reina Haque and Feifei Wei and Timothy L Lash},
journal = {Journal of Clinical Epidemiology},
title = {A most stubborn bias: no adjustment method fully resolves confounding by indication in observational studies},
abstract = {OBJECTIVE: To evaluate the effectiveness of methods that control for confounding by indication, we compared breast cancer recurrence rates among women receiving adjuvant chemotherapy with those who did not. STUDY DESIGN AND SETTING: In a medical record review-based study of breast cancer treatment in older women (n=1798) diagnosed between 1990 and 1994, our crude analysis suggested that adjuvant chemotherapy was positively associated with recurrence (hazard ratio [HR]=2.6; 95% confidence interval [CI]=1.9, 3.5). We expected a protective effect, so postulated that the crude association was confounded by indications for chemotherapy. We attempted to adjust for this confounding by restriction, multivariable regression, propensity scores (PSs), and instrumental variable (IV) methods. RESULTS: After restricting to women at high risk for recurrence (n=946), chemotherapy was not associated with recurrence (HR=1.1; 95% CI=0.7, 1.6) using multivariable regression. PS adjustment yielded similar results (HR=1.3; 95% CI=0.8, 2.0). The IV-like method yielded a protective estimate (HR=0.9; 95% CI=0.2, 4.3); however, imbalances of measured factors across levels of the IV suggested residual confounding. CONCLUSION: Conventional methods do not control for unmeasured factors, which often remain important when addressing confounding by indication. PS and IV analysis methods can be useful under specific situations, but neither method adequately controlled confounding by indication in this study.},
affiliation = {Department of Medicine, Geriatrics Section, Boston University School of Medicine, Boston, MA 02118, USA. jfong@bu.edu},
number = {1},
pages = {64--74},
volume = {63},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-02-24 20:33:38 +0100},
date-modified = {2010-02-24 20:33:39 +0100},
doi = {10.1016/j.jclinepi.2009.03.001},
pii = {S0895-4356(09)00060-2},
pmid = {19457638},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Bosco-2010-Journal%20of%20Clinical%20Epidemiology_A%20most%20stubborn%20bias.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6525},
rating = {0}
}

@article{Murray:2004p9334,
author = {David M Murray and Sherri P Varnell and Jonathan L Blitstein},
journal = {Am J Public Health},
title = {Design and analysis of group-randomized trials: a review of recent methodological developments},
abstract = {We review recent developments in the design and analysis of group-randomized trials (GRTs). Regarding design, we summarize developments in estimates of intraclass correlation, power analysis, matched designs, designs involving one group per condition, and designs in which individuals are randomized to receive treatments in groups. Regarding analysis, we summarize developments in marginal and conditional models, the sandwich estimator, model-based estimators, binary data, survival analysis, randomization tests, survey methods, latent variable methods and nonlinear mixed models, time series methods, global tests for multiple endpoints, mediation effects, missing data, trial reporting, and software. We encourage investigators who conduct GRTs to become familiar with these developments and to collaborate with methodologists who can strengthen the design and analysis of their trials.},
affiliation = {Department of Psychology, College of Arts and Sciences, University of Memphis, Memphis, TN, USA. d.murray@mail.psyc.memphis.edu},
number = {3},
pages = {423--32},
volume = {94},
year = {2004},
month = {Mar},
language = {eng},
keywords = {Epidemiologic Research Design, Public Health Practice, Cluster Analysis, Intervention Studies, Software, Randomized Controlled Trials as Topic, Humans, Time Factors},
date-added = {2010-03-23 18:38:05 +0100},
date-modified = {2010-07-29 19:14:25 +0200},
pmid = {14998806},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Murray-2004-Am%20J%20Public%20Health_Design%20and%20analysis.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9334},
rating = {0}
}

@article{Lin:2009p11162,
author = {T H Lin and G Yao},
journal = {Socioeconomic Indicators Research},
title = {Evaluating Item Discrimination Power of WHOQOL- BREF from an Item Response Model Perspectives},
abstract = {Quality of life (QOL) has become an important component of health. By using the methodology of psychometric theory, we examine the item properties of the WHOQOL-BRIEF. Samejima's graded response model with natural metrics of the logistic response function was fitted. The results showed items with negative natures were less discriminating. Items written in a specific way were more suitable to assess certain sub- groups. The national items showed variation in discriminatory power. Questions measuring objective and specific issues performed worse than items assessing general aspects of the QOL.},
pages = {141--153},
volume = {91},
year = {2009},
date-added = {2010-04-25 20:29:03 +0200},
date-modified = {2010-04-25 21:03:58 +0200},
doi = {10.1007/s11205-008-9273-0},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Lin-2009-Socioeconomic%20Indicators%20Research_Evaluating%20Item%20Disc.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11162},
rating = {4}
}

@article{Fox:2005p1833,
author = {J P Fox},
journal = {Journal of Educational and Behavioral Statistics},
title = {Randomized Item Response Theory Models},
abstract = {The randomized response (RR) technique is often used to obtain answers on sen- sitive questions. A new method is developed to measure latent variables using the RR technique because direct questioning leads to biased results. Within the RR technique is the probability of the true response modeled by an item response theory (IRT) model. The RR technique links the observed item response with the true item response. Attitudes can be measured without knowing the true individ- ual answers. This approach makes also a hierarchical analysis possible, with explanatory variables, given observed RR data. All model parameters can be esti- mated simultaneously using Markov chain Monte Carlo. The randomized item response technique was applied in a study on cheating behavior of students at a Dutch University. In this study, it is of interest if students' cheating behavior dif- fers across studies and if there are indicators that can explain differences in cheating behavior.},
number = {2},
pages = {1--24},
volume = {30},
year = {2005},
keywords = {Analysis of Variance, Markov chain Monte Carlo (MCMC), item response theory model, random effects, randomized response},
date-added = {2010-01-09 23:00:41 +0100},
date-modified = {2010-01-09 23:02:08 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fox-2005-Journal%20of%20Educational%20and%20Behavioral%20Statistics_Randomized%20Item%20Resp.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1833},
rating = {0}
}

@article{Cooper:2006p10197,
author = {Robbie M Cooper and Stephen R H Langton},
journal = {Behaviour Research and Therapy},
title = {Attentional bias to angry faces using the dot-probe task? It depends when you look for it},
abstract = {A number of studies using the dot-probe task now report the existence of an attentional bias to angry faces in participants who rate highly on scales of anxiety; however, no equivalent bias has been observed in non-anxious populations, despite evidence to the contrary from studies using other tasks. One reason for this discrepancy may be that researchers using the dot-probe task have rarely investigated any effects which might emerge earlier than 500 ms following presentation of the threat-related faces. Accordingly, in the current study we presented pairs of face stimuli with emotional and neutral expressions and probed the allocation of attention to these stimuli for presentation times of 100 and 500 ms. Results showed that at 100 ms there was an attentional bias towards the location of the relatively threatening stimulus (the angry face in angry/neutral pairs and the neutral face in neutral/happy pairs) and this pattern reversed by 500 ms. Comparisons of reaction time (RT) scores with an appropriate baseline suggested that the early bias toward threatening faces may actually arise through inhibition of the relatively least threatening member of a face pair rather than through facilitation of, or vigilance towards, the more threatening stimulus. However the mechanisms governing the observed biases are interpreted, these data provide evidence that probing for the location of spatial attention at 500 ms is not necessarily indicative of the initial allocation of attention between competing emotional facial stimuli.},
affiliation = {Department of Psychology, University of Stirling, Stirling, FK9 4LA, UK. r.m.cooper@stir.ac.uk},
number = {9},
pages = {1321--9},
volume = {44},
year = {2006},
month = {Sep},
language = {eng},
keywords = {Female, Facial Expression, Humans, Anger, Pattern Recognition: Visual, Adult, Reaction Time, Emotions, Attention, Male, Photic Stimulation},
date-added = {2010-04-01 18:17:40 +0200},
date-modified = {2010-07-29 19:18:49 +0200},
doi = {10.1016/j.brat.2005.10.004},
pii = {S0005-7967(05)00213-5},
pmid = {16321361},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Cooper-2006-Behaviour%20Research%20and%20Therapy_Attentional%20bias%20to-1.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10197},
rating = {0}
}

@article{Agarwal:2007p12878,
author = {D Agarwal and S Merugu},
journal = {KDD},
title = {Predictive Discrete Latent Factor Models for Large Scale Dyadic Data},
abstract = {We propose a novel statistical method to predict large scale dyadic response variables in the presence of covariate information. Our approach simultaneously incorporates the effect of covariates and estimates local structure that is induced by interactions among the dyads through a discrete latent factor model. The discovered la- tent factors provide a predictive model that is both accurate and interpretable. We illustrate our method by working in a framework of generalized linear models, which include commonly used re- gression techniques like linear regression, logistic regression and Poisson regression as special cases. We also provide scalable gen- eralized EM-based algorithms for model fitting using both "hard" and "soft" cluster assignments. We demonstrate the generality and efficacy of our approach through large scale simulation studies and analysis of datasets obtained from certain real-world movie recom- mendation and internet advertising applications.},
year = {2007},
date-added = {2010-06-24 13:02:07 +0200},
date-modified = {2010-06-24 13:02:45 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Agarwal-2007-KDD_Predictive%20Discrete.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12878},
rating = {0}
}

@article{Ai:2003p4115,
author = {C Ai and E C Norton},
journal = {Economics Letters},
title = {Interaction terms in logit and probit models},
abstract = {The magnitude of the interaction effect in nonlinear models does not equal the marginal effect of the interaction term, can be of opposite sign, and its statistical significance is not calculated by standard software. We present the correct way to estimate the magnitude and standard errors of the interaction effect in nonlinear models.},
pages = {123--129},
volume = {80},
year = {2003},
date-added = {2010-01-20 00:02:39 +0100},
date-modified = {2010-01-20 00:03:17 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Ai-2003-Economics%20Letters_Interaction%20terms%20in.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4115},
rating = {0}
}

@article{Potter:2006p10064,
author = {Douglas M Potter and Derek J Griffiths},
journal = {J Biopharm Stat},
title = {Omnibus permutation tests of the overall null hypothesis in datasets with many covariates},
abstract = {Tests of the overall null hypothesis in datasets with one outcome variable and many covariates can be based on various methods to combine the p-values for univariate tests of association of each covariate with the outcome. The overall p-value is computed by permuting the outcome variable. We discuss the situations in which this approach is useful and provide several examples. We use simulations to investigate seven omnibus test statistics and find that the Anderson-Darling and Fisher's statistics are superior to the others.},
affiliation = {Biostatistics Department, Graduate School of Public Health, University of Pittsburgh and Biostatistics Facility, University of Pittsburgh Cancer Institute, PA 15213, USA. potter@upci.pitt.edu},
number = {3},
pages = {327--41},
volume = {16},
year = {2006},
month = {May},
language = {eng},
keywords = {Data Interpretation: Statistical, Randomized Controlled Trials as Topic, Male, Humans, Parasympatholytics, Models: Statistical, Mandelic Acids, Oxidative Phosphorylation, Gene Expression Profiling, Urinary Incontinence, Glucose Intolerance, Statistics: Nonparametric, Computer Simulation, Regression Analysis, Research Design},
date-added = {2010-03-31 20:17:29 +0200},
date-modified = {2010-07-29 19:32:23 +0200},
pmid = {16724488},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p10064},
rating = {0}
}

@article{Handlos:2009p6398,
author = {Line Neerup Handlos and Hrishikesh Chakraborty and Pranab Kumar Sen},
journal = {Trop Med Int Health},
title = {Evaluation of cluster-randomized trials on maternal and child health research in developing countries},
abstract = {OBJECTIVE: To summarize and evaluate all publications including cluster-randomized trials used for maternal and child health research in developing countries during the last 10 years. METHODS: All cluster-randomized trials published between 1998 and 2008 were reviewed, and those that met our criteria for inclusion were evaluated further. The criteria for inclusion were that the trial should have been conducted in maternal and child health care in a developing country and that the conclusions should have been made on an individual level. Methods of accounting for clustering in design and analysis were evaluated in the eligible trials. RESULTS: Thirty-five eligible trials were identified. The majority of them were conducted in Asia, used community as randomization unit, and had less than 10,000 participants. To minimize confounding, 23 of the 35 trials had stratified, blocked, or paired the clusters before they were randomized, while 17 had adjusted for confounding in the analysis. Ten of the 35 trials did not account for clustering in sample size calculations, and seven did not account for the cluster-randomized design in the analysis. The number of cluster-randomized trials increased over time, and the trials generally improved in quality. CONCLUSIONS: Shortcomings exist in the sample-size calculations and in the analysis of cluster-randomized trials conducted during maternal and child health research in developing countries. Even though there has been improvement over time, further progress in the way that researchers utilize and analyse cluster-randomized trials in this field is needed.},
affiliation = {Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA. lneerup@gmail.com},
number = {8},
pages = {947--56},
volume = {14},
year = {2009},
month = {Aug},
language = {eng},
keywords = {Infant, Child, Maternal-Child Health Centers, Cluster Analysis, Infant: Newborn, Humans, Child: Preschool, Developing Countries, Research Design, Female, Randomized Controlled Trials as Topic, Male, Pregnancy},
date-added = {2010-02-23 08:25:46 +0100},
date-modified = {2010-02-23 08:25:46 +0100},
doi = {10.1111/j.1365-3156.2009.02313.x},
pii = {TMI2313},
pmid = {19563429},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6398},
rating = {0}
}

@article{Senra:1993p12755,
author = {C Senra and A Polaino},
journal = {J Affect Disord},
title = {Concordance between clinical and self-report depression scales during the acute phase and after treatment},
abstract = {The concordance between self-report and clinical rating scales of depression increases during progress from the acute depressive episode to recovery or improvement of symptoms. We investigated this convergence in a group of 52 outpatients with DSM-III major depression disorders using three widely employed depression scales and their parallel formats (i.e., alternative modes of administering the scales). The six instruments were applied at admission and after 12 and 24 weeks' treatment. The results indicate that the increase in the global concordance between scales may be a statistical effect deriving from broadening of the range of scores.},
affiliation = {Universidad de Santiago de Compostela, Spain.},
number = {1},
pages = {13--9},
volume = {27},
year = {1993},
month = {Jan},
language = {eng},
keywords = {Antidepressive Agents: Tricyclic, Personality Assessment, Humans, Depressive Disorder, Male, Adult, Personality Inventory, Psychometrics, Female, Follow-Up Studies},
date-added = {2010-06-15 22:51:38 +0200},
date-modified = {2010-06-15 22:51:47 +0200},
pmid = {8432955},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Senra-1993-J%20Affect%20Disord_Concordance%20between.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12755},
rating = {3}
}

@article{Vinkhuyzen:2009p7669,
author = {Anna A E Vinkhuyzen and Sophie van der Sluis and Dorret I Boomsma and Eco J C de Geus and Danielle Posthuma},
journal = {Behav Genet},
title = {Individual Differences in Processing Speed and Working Memory Speed as Assessed with the Sternberg Memory Scanning Task},
abstract = {The Sternberg Memory Scanning (SMS) task provides a measure of processing speed (PS) and working memory retrieval speed (WMS). In this task, participants are presented with sets of stimuli that vary in size. After a delay, one item is presented, and participants indicate whether or not the item was part of the set. Performance is assessed by speed and accuracy for both the positive (item is part of the set) and the negative trials (items is not part of the set). To examine the causes of variation in PS and WMS, 623 adult twins and their siblings completed the SMS task. A non-linear growth curve (nLGC) model best described the increase in reaction time with increasing set size. Genetic analyses showed that WMS (modeled as the Slope in the nLGC model) has a relatively small variance which is not due to genetic variation while PS (modeled as the Intercept in the nLGC model) showed large individual differences, part of which could be attributed to additive genetic factors. Heritability was 38% for positive and 32% for negative trials. Additional multivariate analyses showed that the genetic effects on PS for positive and negative trials were completely shared. We conclude that genetic influences on working memory performance are more likely to act upon basic processing speed and (pre)motoric processes than on the speed with which an item is retrieved from short term memory.},
affiliation = {Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands, aae.vinkhuyzen@psy.vu.nl.},
pages = {},
year = {2009},
month = {Nov},
language = {ENG},
date-added = {2010-03-15 23:44:48 +0100},
date-modified = {2010-07-29 20:09:06 +0200},
doi = {10.1007/s10519-009-9315-7},
pmid = {20091112},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Vinkhuyzen-2009-Behav%20Genet_Individual%20Differenc.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7669},
rating = {0}
}

@article{Liu:2005p4622,
author = {H Liu and G Li and W G Cumberland and T Wu},
journal = {Journal of Data Science},
title = {Testing Statistical Significance of the Area under a Receiving Operating Characteristics Curve for Repeated Measures Design with Bootstrapping},
abstract = {Receiver operating characteristic (ROC) curve is an effective and widely used method for evaluating the discriminating power of a diagnostic test or statistical model. As a useful statistical method, a wealth of lit- erature about its theories and computation methods has been established. The research on ROC curves, however, has focused mainly on cross-sectional design. Very little research on estimating ROC curves and their summary statistics, especially significance testing, has been conducted for repeated measures design. Due to the complexity of estimating the standard error of a ROC curve, there is no currently established statistical method for testing the significance of ROC curves under a repeated measures design. In this paper, we estimate the area of a ROC curve under a repeated measures de- sign through generalized linear mixed model (GLMM) using the predicted probability of a disease or positivity of a condition and propose a bootstrap method to estimate the standard error of the area under a ROC curve for such designs. Statistical significance testing of the area under a ROC curve is then conducted using the bootstrapped standard error. The validity of bootstrap approach and the statistical testing of the area under the ROC curve was validated through simulation analyses. A special statistical soft- ware written in SAS/IML/MACRO v8 was also created for implementing the bootstrapping algorithm, conducting the calculations and statistical testing.},
pages = {257--278},
volume = {3},
year = {2005},
date-added = {2010-01-30 15:30:06 +0100},
date-modified = {2010-01-30 15:30:53 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Liu-2005-Journal%20of%20Data%20Science_Testing%20Statistical.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4622},
rating = {0}
}

@article{Verguts:2000,
author = {Tom Verguts and Paul De Boeck},
journal = {Methods of Psychological Research Online},
title = {A note on the Martin-L{\"o}f test for unidimensionality},
number = {1},
volume = {5},
year = {2000},
date-added = {2010-01-10 11:33:23 +0100},
date-modified = {2010-07-29 20:46:12 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Verguts-2000-Methods%20of%20Psychological%20Research%20Online_A%20note%20on%20the%20Martin.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2178},
rating = {0}
}

@article{Steiger:2010p2931,
author = {J H Steiger},
title = {Confirmatory Factor Analysis with R},
date-added = {2010-01-13 22:17:59 +0100},
date-modified = {2010-01-13 22:18:32 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Steiger--_Confirmatory%20Factor.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2931},
rating = {0}
}

@article{Dolnicar:2002p13229,
author = {S Dolnicar},
title = {A Review of Unquestioned Standards in Using Cluster Analysis for Data-Driven Market Segmentation},
abstract = {Clustering is a highly popular and widely used tool for identifying or constructing databased market segments. Over decades of applying cluster analytical procedures for the purpose of searching for homogeneous subgroups among consumers, questionable standards of utilization have emerged, e.g. the non-explorative manner in which results from cluster analytic procedures are reported, the black-box approach ignoring crucial parameters of the algorithms applied or the lack of harmonization of methodology chosen and data conditions. The purpose of this study is threefold: (1) to investigate whether and which standards of application of cluster analysis have emerged in the academic marketing literature, (2) to compare these standards of application to methodological knowledge about clustering procedures and (3) suggest changes in clustering habits. These goals are achieved by systematically reviewing 243 data-driven segmentation studies that apply cluster analysis for partitioning purposes.},
year = {2002},
date-added = {2010-07-01 17:25:01 +0200},
date-modified = {2010-07-01 17:25:39 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Dolnicar-2002-_A%20Review%20of%20Unquesti.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13229},
read = {Yes},
rating = {0}
}

@article{Wessman:2009p9856,
author = {Jaana Wessman and Tiina Paunio and Annamari Tuulio-Henriksson and Mikko Koivisto and Timo Partonen and Jaana Suvisaari and Joni A Turunen and Juho Wedenoja and William Hennah and Olli P H Pietil{\"a}inen and Jouko L{\"o}nnqvist and Heikki Mannila and Leena Peltonen},
journal = {Biol Psychiatry},
title = {Mixture model clustering of phenotype features reveals evidence for association of DTNBP1 to a specific subtype of schizophrenia},
abstract = {BACKGROUND: While DTNBP1, DISC1, and NRG1 have been extensively studied as candidate genes of schizophrenia, results remain inconclusive. Possible explanations for this are that the genes might be relevant only to certain subtypes of the disease and/or only in certain populations. METHODS: We performed unsupervised clustering of individuals from Finnish schizophrenia families, based on extensive clinical and neuropsychological data, including Structured Clinical Interview for DSM-IV (SCID) information. Families with at least one affected member with DSM-IV diagnosis of a schizophrenia spectrum psychosis were included in a register-based ascertainment. Final sample consisted of 904 individuals from 288 families. We then used the cluster phenotypes in a genetic association study of candidate genes. RESULTS: A robust three-class clustering of individuals emerged: 1) psychotic disorder with mood symptoms (n = 172), 2) core schizophrenia (n = 223), and 3) absence of psychotic disorder (n = 509). One third of the individuals diagnosed with schizophrenia were assigned to cluster 1. These individuals had fewer negative and positive psychotic symptoms and cognitive deficits but more depressive symptoms than individuals in cluster 2. There was a significant association of cluster 2 cases with the DTNBP1 gene, while the DISC1 gene indicated a significant association with schizophrenia spectrum disorders based on the DSM-IV criteria. CONCLUSIONS: In the Finnish population, DTNBP1 gene is associated with a schizophrenia phenotype characterized by prominent negative symptoms, generalized cognitive impairment, and few mood symptoms. Identification of genes and pathways related to schizophrenia necessitates novel definitions of disease phenotypes associated more directly with underlying biology.},
affiliation = {Department of Molecular Medicine, Helsinki, Finland. jaana.wessman@cs.helsinki.fi},
number = {11},
pages = {990--6},
volume = {66},
year = {2009},
month = {Dec},
language = {eng},
keywords = {Neuregulin-1, Nerve Tissue Proteins, Polymorphism: Single Nucleotide, Schizophrenic Psychology, Aged, Phenotype, Cluster Analysis, Humans, Psychotic Disorders, Middle Aged, Alleles, Genetic Association Studies, Adult, Carrier Proteins, Schizophrenia},
date-added = {2010-03-26 19:30:58 +0100},
date-modified = {2010-03-26 19:30:58 +0100},
doi = {10.1016/j.biopsych.2009.05.034},
pii = {S0006-3223(09)00831-2},
pmid = {19782967},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9856},
rating = {0}
}

@article{Yu:2008,
author = {Q Yu and E Stasny and B Li},
journal = {Annals of Applied Probability},
title = {Bayesian models to adjust for response bias in survey data for estimating rape and domestic violence rates from the NCVS},
year = {2008},
date-added = {2010-01-10 11:33:17 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Yu-2008-Annals%20of%20Applied%20Probability_Bayesian%20models%20to%20a.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1872},
rating = {0}
}

@article{Henson:2001,
author = {R K Henson and L R Kogan and T Vacha-Haase},
journal = {Educational and Psychological Measurement},
title = {A reliability generalization study of the Teacher Efficacy Scale and related instruments},
number = {404-420},
volume = {61},
year = {2001},
date-added = {2010-01-10 11:33:21 +0100},
date-modified = {2010-01-10 11:33:25 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1998},
rating = {0}
}

@article{Pfeffermann:1993p6310,
author = {D Pfeffermann},
journal = {International Statistical Review},
title = {The Role of Sampling Weights When Modeling Survey Data},
abstract = {The purposeof this paperis to providea criticalsurveyof the literature,directedat answering two main questions.i) Can the use of the samplingweightsbe justifiedfor analyticinferenceabout modelparametersandif so, underwhatcircumstances?ii) Canguidelinesbe developedfor how to
incorporatethe weightsin the analysis?The generalconclusionof thisstudyis thatthe weightscan be used to test and protectagainstinformativesamplingdesignsand againstmisspecificationof the model holding in the population. Six approachesfor incorporatingthe weights in the inference processare considered.The firstfour approachesare intendedto yield design consistentestimators for correspondingdescriptivepopulationquantitiesof the model parameters.The other two approachesattemptto incorporatethe weightsinto the model.},
number = {2},
pages = {317--337},
volume = {61},
year = {1993},
date-added = {2010-02-20 21:04:43 +0100},
date-modified = {2010-02-20 21:05:40 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Pfeffermann-1993-International%20Statistical%20Review_The%20Role%20of%20Sampling.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6310},
rating = {0}
}

@article{Wang:2008p5891,
author = {H Wang and C Leng},
journal = {Computational Statistics},
title = {A note on adaptive group lasso},
abstract = {Group lasso is a natural extension of lasso and selects variables in a grouped manner. However, group lasso suffers from estimation inefficiency and selection inconsistency. To remedy these problems, we propose the adaptive group lasso method. We show theoretically that the new method is able to identify the true model consistently, and the resulting estimator can be as efficient as oracle. Numerical studies confirmed our theoretical findings.},
pages = {5277--5286},
volume = {52},
year = {2008},
date-added = {2010-02-17 21:05:40 +0100},
date-modified = {2010-07-29 19:24:30 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wang-2008-Computational%20Statistics_A%20note%20on%20adaptive%20g.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5891},
rating = {0}
}

@article{Sawatzky:2010p5235,
author = {Richard Sawatzky and Pamela A Ratner and Joy L Johnson and Jacek A Kopec and Bruno D Zumbo},
journal = {Health Qual Life Outcomes},
title = {Self-reported physical and mental health status and quality of life in adolescents: a latent variable mediation model},
abstract = {ABSTRACT: BACKGROUND: We examined adolescents' differentiation of their self-reported physical and mental health status, the relative importance of these variables and five important life domains (satisfaction with family, friends, living environment, school and self) with respect to adolescents' global quality of life (QOL), and the extent to which the five life domains mediate the relationships between self-reported physical and mental health status and global QOL. METHODS: The data were obtained via a cross-sectional health survey of 8,225 adolescents in 49 schools in British Columbia, Canada. Structural equation modeling was applied to test the implied latent variable mediation model. The Pratt index (d) was used to evaluate variable importance. RESULTS: Relative to one another, self-reported mental health status was found to be more strongly associated with depressive symptoms, and self-reported physical health status more strongly associated with physical activity. Self-reported physical and mental health status and the five life domains explained 76% of the variance in global QOL. Relatively poorer mental health and physical health were significantly associated with lower satisfaction in each of the life domains. Global QOL was predominantly explained by three of the variables: mental health status (d = 30%), satisfaction with self (d = 42%), and satisfaction with family (d = 20%). Satisfaction with self and family were the predominant mediators of mental health and global QOL (45% total mediation), and of physical health and global QOL (68% total mediation). CONCLUSIONS: This study provides support for the validity and relevance of differentiating self-reported physical and mental health status in adolescent health surveys. Self-reported mental health status and, to a lesser extent, self-reported physical health status were associated with significant differences in the adolescents' satisfaction with their family, friends, living environment, school experiences, self, and their global QOL. Questions about adolescents' self-reported physical and mental health status and their experiences with these life domains require more research attention so as to target appropriate supportive services, particularly for adolescents with mental or physical health challenges.},
number = {1},
pages = {17},
volume = {8},
year = {2010},
month = {Feb},
language = {ENG},
date-added = {2010-02-08 19:33:17 +0100},
date-modified = {2010-07-29 20:46:35 +0200},
doi = {10.1186/1477-7525-8-17},
pii = {1477-7525-8-17},
pmid = {20128913},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sawatzky-2010-Health%20Qual%20Life%20Outcomes_Self-reported%20physic.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5235},
rating = {4}
}

@article{Gratacos:2010p7572,
author = {M{\`o}nica Gratac{\`o}s and Ge{\`o}rgia Escaram{\'\i}s and Mariona Bustamante and Ester Saus and Zaida Ag{\"u}era and M{\`o}nica Bay{\'e}s and Elena Cellini and Rafael de Cid and Fernando Fern{\'a}ndez-Aranda and Laura Forcano and Juan R Gonz{\'a}lez and Philip Gorwood and Johannes Hebebrand and Anke Hinney and Josep M Mercader and Benedetta Nacmias and Nicolas Ramoz and Marta Ribas{\'e}s and Valdo Ricca and Lucia Romo and Sandro Sorbi and Audrey Versini and Xavier Estivill},
journal = {J Psychiatr Res},
title = {Role of the neurotrophin network in eating disorders' subphenotypes: Body mass index and age at onset of the disease},
abstract = {Eating disorders (ED) are severe psychiatric diseases that most likely result from, and are sustained by socio-cultural, psychological and biological factors. We explored whether members of the neurotrophin family are disease-modifying factors of quantitative traits, potentially contributing to the outcome or prognosis of the disease. We studied lifetime minimum and maximum body mass index (minBMI and maxBMI) and age at onset of the disease in a sample of 991 ED patients from France, Germany, Italy and Spain and analysed 183 genetic variants located in 10 candidate genes encoding different neurotrophins and their receptors. We used a hierarchical model approach to include prior genetic knowledge of the specific and found that variants in CNTF, in its receptor CNTFR, and in NTRK2 were significantly associated with a lower age at onset of the ED. In addition, one variant in NTRK1 was associated with a higher minBMI. The results suggest that for these two subphenotypes, CNTF, CNTFR, NTRK1 and NTRK2 might act as disease-modifying factors and add preliminary evidence to the global hypothesis that EDs are the result of complex interactions and reciprocal controls between the immune, endocrine and central nervous systems.},
affiliation = {CIBER en Epidemiolog{\'\i}a y Salud P{\'u}blica (CIBERESP), Genes and Disease Program, Center for Genomic Regulation (CRG-UPF), Barcelona 08003, Catalonia, Spain.},
pages = {},
year = {2010},
month = {Mar},
language = {ENG},
date-added = {2010-03-14 11:01:00 +0100},
date-modified = {2010-07-29 19:35:54 +0200},
doi = {10.1016/j.jpsychires.2010.01.009},
pii = {S0022-3956(10)00018-X},
pmid = {20219210},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Gratac%C3%B2s-2010-J%20Psychiatr%20Res_Role%20of%20the%20neurotro.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7572},
rating = {3}
}

@article{Fone:2006p7521,
author = {David L Fone and Daniel M Farewell and Frank D Dunstan},
journal = {Popul Health Metr},
title = {An ecometric analysis of neighbourhood cohesion},
abstract = {BACKGROUND: It is widely believed that the social environment has an important influence on health, but there is less certainty about how to measure specific factors within the social environment that could link the neighbourhood of residence to a health outcome. The objectives of the study were to examine the underlying constructs captured by an adapted version of Buckner's neighbourhood cohesion scale, and to assess the reliability of the scale at the small-area-level by combining ecometric methodology with ordinal modelling of a five-point scale. METHODS: Data were analysed from 11,078 participants in the Caerphilly Health and Social Needs Study, who were sampled from within 325 UK census enumeration districts in Caerphilly county borough, Wales, UK. The responses of interest came from 15 question items designed to capture different facets of neighbourhood cohesion. Factor analysis was used to identify constructs underlying the neighbourhood cohesion item responses. Using a multilevel ecometric model, the variability present in these ordinal responses was decomposed into contextual, compositional, item-level and residual components. RESULTS: Two constructs labelled neighbourhood belonging and social cohesion were identified, and variability in both constructs was modelled at each level of the multilevel structure. The intra-neighbourhood correlations were 6.4% and 1.0% for the neighbourhood belonging and social cohesion subscales, respectively. Given the large sample size, contextual neighbourhood cohesion scores can be estimated reliably. The wide variation in the observed frequency of occurence of the scale item activities suggests that the two subscales have desirable ecometric properties. Further, the majority of between-neighbourhood variation is not explained by the socio-demographic characteristics of the individual respondents. CONCLUSION: Assessment of the properties of the adapted neighbourhood cohesion scale using factor analysis and ecometric analysis extended to an ordinal scale has shown that the items allow fine discrimination between individuals. However, large sample sizes are needed in order to accurately estimate contextual neighbourhood cohesion. The scale is therefore appropriate for use in the measurement of neighbourhood cohesion at small-area-level in future studies of neighbourhoods and health.},
affiliation = {Department of Epidemiology, Statistics and Public Health, Centre for Health Sciences Research, School of Medicine, Cardiff University, Neuadd Meirionnydd, Heath Park, Cardiff, Wales, CF14 4YS, UK. foned@cf.ac.uk},
pages = {17},
volume = {4},
year = {2006},
month = {Jan},
language = {eng},
date-added = {2010-03-14 10:53:26 +0100},
date-modified = {2010-03-14 10:53:26 +0100},
doi = {10.1186/1478-7954-4-17},
pii = {1478-7954-4-17},
pmid = {17184538},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fone-2006-Popul%20Health%20Metr_An%20ecometric%20analysi.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7521},
rating = {0}
}

@article{Schafer:2005p2933,
author = {Juliane Sch{\"a}fer and Korbinian Strimmer},
journal = {Statistical Applications in Genetics and Molecular Biology},
title = {A shrinkage approach to large-scale covariance matrix estimation and implications for functional genomics},
abstract = {Inferring large-scale covariance matrices from sparse genomic data is an ubiquitous problem in bioinformatics. Clearly, the widely used standard covariance and correlation estimators are ill-suited for this purpose. As statistically efficient and computationally fast alternative we propose a novel shrinkage covariance estimator that exploits the Ledoit-Wolf (2003) lemma for analytic calculation of the optimal shrinkage intensity. Subsequently, we apply this improved covariance estimator (which has guaranteed minimum mean squared error, is well-conditioned, and is always positive definite even for small sample sizes) to the problem of inferring large-scale gene association networks. We show that it performs very favorably compared to competing approaches both in simulations as well as in application to real expression data.},
affiliation = {Department of Statistics, University of Munich, Germany. schaefer@stat.math.ethz.ch},
pages = {Article32},
volume = {4},
year = {2005},
month = {Jan},
language = {eng},
date-added = {2010-01-13 22:54:58 +0100},
date-modified = {2010-01-13 22:54:58 +0100},
doi = {10.2202/1544-6115.1175},
pmid = {16646851},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Sch%C3%A4fer-2005-Statistical%20Applications%20in%20Genetics%20and%20Molecular%20Biology_A%20shrinkage%20approach.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2933},
rating = {0}
}

@article{Dobra:2009p3718,
author = {Adrian Dobra},
journal = {Biostatistics},
title = {Variable selection and dependency networks for genomewide data},
abstract = {We describe a new stochastic search algorithm for linear regression models called the bounded mode stochastic search (BMSS). We make use of BMSS to perform variable selection and classification as well as to construct sparse dependency networks. Furthermore, we show how to determine genetic networks from genomewide data that involve any combination of continuous and discrete variables. We illustrate our methodology with several real-world data sets.},
affiliation = {Department of Statistics and Department of Biobehavioral Nursing and Health Systems, University of Washington Seattle, WA 98195, USA. adobra@u.washington.edu},
number = {4},
pages = {621--39},
volume = {10},
year = {2009},
month = {Oct},
language = {eng},
keywords = {Gene Expression, Algorithms, Receptors: Estrogen, Lymphatic Metastasis, Stochastic Processes, Breast Neoplasms, Linear Models, Biostatistics, Humans, Gene Regulatory Networks, Genome-Wide Association Study, Female},
date-added = {2010-01-16 20:56:59 +0100},
date-modified = {2010-01-16 20:56:59 +0100},
doi = {10.1093/biostatistics/kxp018},
pii = {kxp018},
pmid = {19520789},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3718},
rating = {0}
}

@article{Meulders:2005,
author = {M Meulders and E H Ip and Paul De Boeck},
journal = {British Journal of Mathematical {\&} Statistical Psychology},
title = {Latent variable models for partially ordered responses and trajectory analysis of anger-related feelings},
pages = {117--143},
volume = {58},
year = {2005},
date-added = {2010-01-10 11:33:22 +0100},
date-modified = {2010-07-29 20:46:12 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Meulders-2005-British%20Journal%20of%20Mathematical%20&%20Statistical%20Psychology_Latent%20variable%20mode.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1860},
rating = {0}
}

@article{Wang:2009p5142,
author = {Tien-Ni Wang and Mei-Hui Tseng and Brenda N Wilson and Fu-Chang Hu},
journal = {Dev Med Child Neurol},
title = {Functional performance of children with developmental coordination disorder at home and at school},
abstract = {This study investigated the functional performance of daily activities at home and at school in a population-based sample of children with different degrees of motor coordination impairment and competence. Sixteen children (seven males, nine females; mean age 8 y, SD 9 mo) with developmental coordination disorder (DCD), 25 with suspected DCD ([sDCD] 17 males, eight females; mean age 7 y 6 mo, SD 8 mo), and 63 children without motor problems (39 males, 24 females; mean age 7 y 9 mo, SD 7 mo) were recruited from public schools (Grades 1-3, age 6 y 4 mo-9 y 10 mo) using the Chinese version of the Developmental Coordination Disorder Questionnaire, the Movement Assessment Battery for Children, and the Bruininks-Oseretsky Test of Motor Proficiency. Functional performance was assessed using the Chinese versions of the Vineland Adaptive Behavior Scales and the School Function Assessment-Chinese version. The functional performance of children with DCD and sDCD was statistically significantly lower than those without DCD (p's<0.05). chi(2) and logistic regression analyses showed significant differences among all groups in the proportion of children scoring at the 'inadequate' adaptive level of home performance (p's<0.05). There were also significant differences among the groups in the proportion of children scoring below the cut-off in school performance (p's<0.05). The findings show the pervasive impact of DCD on children's functional performance in daily activities at home and at school.},
affiliation = {School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China.},
number = {10},
pages = {817--25},
volume = {51},
year = {2009},
month = {Oct},
language = {eng},
keywords = {Male, Disability Evaluation, Motor Activity, Adaptation: Physiological, Female, Schools, Humans, Child, Severity of Illness Index, Activities of Daily Living, Questionnaires, Educational Status, Chi-Square Distribution, Motor Skills Disorders},
date-added = {2010-02-05 20:19:43 +0100},
date-modified = {2010-07-29 19:25:11 +0200},
doi = {10.1111/j.1469-8749.2009.03271.x},
pii = {DMCN3271},
pmid = {19416344},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5142},
rating = {0}
}

@article{Durlak:2009p14217,
author = {Joseph A Durlak},
journal = {J Pediatr Psychol},
title = {How to select, calculate, and interpret effect sizes},
abstract = {The objective of this article is to offer guidelines regarding the selection, calculation, and interpretation of effect sizes (ESs). To accomplish this goal, ESs are first defined and their important contribution to research is emphasized. Then different types of ESs commonly used in group and correlational studies are discussed. Several useful resources are provided for distinguishing among different types of effects and what modifications might be required in their calculation depending on a study's purpose and methods. This article should assist producers and consumers of research in understanding the role, importance, and meaning of ESs in research reports.},
affiliation = {Department of Psychology, Loyola University Chicago, 6525 N. Sheridan Road, Chicago, IL 60626, USA. jdurlak@luc.edu},
number = {9},
pages = {917--28},
volume = {34},
year = {2009},
month = {Oct},
language = {eng},
keywords = {Models: Statistical, Meta-Analysis as Topic, Research Design, Research, Humans, Statistics as Topic},
date-added = {2010-08-22 20:53:39 +0200},
date-modified = {2010-08-22 20:53:40 +0200},
doi = {10.1093/jpepsy/jsp004},
pii = {jsp004},
pmid = {19223279},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Durlak-2009-J%20Pediatr%20Psychol_How%20to%20select%20calcu.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p14217},
rating = {4}
}

@article{OHara:2010p4930,
author = {R B O'Hara and P Komulainen and O Savolainen and M J Sillanp{\"a}{\"a}},
journal = {Nature Precedings},
title = {A Latent Variable Approach to Multivariate Quantitative Trait Loci},
abstract = {A novel approach based on latent variable modelling is presented for the analysis of multivariate quantitative and qualitative trait loci. The approach is general in the sense that it enables the joint analysis of many kinds of quantitative and qualitative traits (including count data and censored traits) in a single modelling framework. In the framework, the observations are modelled as functions of latent variables, which are then affected by quantitative trait loci. Separating the analysis in this way means that measurement errors in the phenotypic observations can be included easily in the model, providing robust inferences. The performance of the method is illustrated using two real multivariate datasets, from barley and Scots pine.},
number = {4137.1},
year = {2010},
date-added = {2010-02-02 11:50:39 +0100},
date-modified = {2010-02-02 11:51:42 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/O'Hara-2010-Nature%20Precedings_A%20Latent%20Variable%20Ap.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4930},
rating = {0}
}

@article{Erosheva:2005p6280,
author = {E A Erosheva},
journal = {Psychometrika},
title = {COMPARING LATENT STRUCTURES OF THE GRADE OF MEMBERSHIP, RASCH, AND LATENT CLASS MODELS},
abstract = {This paper focuses on model interpretation issues and employs a geometric approach to compare the potential value of using the Grade of Membership (GoM) model in representing population heterogeneity. We consider population heterogeneity manifolds generated by letting subject specific parameters vary over their natural range, while keeping other population parameters fixed, in the marginal space (based on marginal probabilities) and in the full parameter space (based on cell probabilities). The case of a 2 × 2 contingency table is discussed in detail, and a generalization to 2J tables with J ≥ 3 is sketched. Our approach highlights the main distinction between the GoM model and the probabilistic mixture of classes by demonstrating geometrically the difference between the concepts of partial and probabilistic memberships. By using the geometric approach we show that, in special cases, the GoM model can be thought of as being similar to an item response theory (IRT) model in representing population heterogeneity. Finally, we show that the GoM item parameters can provide quantities analogous to more general logistic IRT item parameters. As a latent structure model, the GoM model might be considered a useful alternative for a data analysis when both classes of extreme responses, and additional heterogeneity that cannot be captured by those latent classes, are expected in the population.},
number = {4},
pages = {619--628},
volume = {70},
year = {2005},
date-added = {2010-02-20 18:02:29 +0100},
date-modified = {2010-02-20 18:03:16 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Erosheva-2005-Psychometrika_COMPARING%20LATENT%20STR.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p6280},
rating = {0}
}

@article{Straetmans:2003aa,
author = {Gerard J J M Straetmans and Theo J H M Eggen},
title = {Computerize Adaptive Testing: What It Is and How It Works},
year = {2003},
month = {Jan},
date-added = {2010-01-03 19:39:03 +0100},
date-modified = {2010-01-03 19:39:03 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Straetmans-2003-_Computerize%20Adaptive.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1205},
rating = {0}
}

@article{Banerjee:2010p12322,
author = {O Banerjee and L El Ghaoui and A d'Aspremont},
journal = {Journal of Machine Learning},
title = {Model Selection Through Sparse Maximum Likelihood Estimation for Multivariate Gaussian or Binary Data},
abstract = {We consider the problem of estimating the parameters of a Gaussian or binary distribution in such a way that the resulting undirected graphical model is sparse. Our approach is to solve a maximum likelihood problem with an added l1-norm penalty term. The problem as formulated is convex but the memory requirements and complexity of existing interior point methods are prohibitive for problems with more than tens of nodes. We present two new algorithms for solving problems with at least a thousand nodes in the Gaussian case. Our first algorithm uses block coordinate descent, and can be interpreted as recursive l1-norm penalized regression. Our second algorithm, based on Nesterov's first order method, yields a complexity estimate with a better dependence on problem size than existing interior point methods. Using a log determinant relaxation of the log partition function (Wainwright and Jordan [2006]), we show that these same algorithms can be used to solve an approximate sparse maximum likelihood problem for the binary case. We test our algorithms on synthetic data, as well as on gene expression and senate voting records data.},
date-added = {2010-06-12 09:40:44 +0200},
date-modified = {2010-07-29 19:34:45 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Banerjee--Journal%20of%20Machine%20Learning_Model%20Selection%20Thro.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12322},
read = {Yes},
rating = {0}
}

@article{Velthove:2010p11907,
author = {Karin J Velthove and Hubert Gm Leufkens and Patrick C Souverein and Rene C Schweizer and Wouter W van Solinge},
journal = {Emerging themes in epidemiology},
title = {Testing bias in clinical databases: methodological considerations},
abstract = {ABSTRACT: BACKGROUND: Laboratory testing in clinical practice is never a random process. In this study we evaluated testing bias for neutrophil counts in clinical practice by using results from requested and non-requested hematological blood tests. METHODS: This study was conducted using data from the Utrecht Patient Oriented Database, a unique clinical database as it contains physician requested data, but also data that are not requested by the physician, but measured as result of requesting other hematological parameters. We identified adult patients, hospitalized in 2005 with at least two blood tests during admission, where requests for general blood profiles and specifically for neutrophil counts were contrasted in scenario analyses. Possible effect modifiers were diagnosis and glucocorticoid use. RESULTS: A total of 567 patients with requested neutrophil counts and 1,439 patients with non-requested neutrophil counts were analyzed. The absolute neutrophil count at admission differed with a mean of 7.4.10E9/l for requested counts and 8.3.10E9/l for non-requested counts (p-value <0.001). This difference could be explained for 83.2% by the occurrence of cardiovascular disease as underlying disease and for 4.5% by glucocorticoid use. CONCLUSION: Requests for neutrophil counts in clinical databases are associated with underlying disease and with cardiovascular disease in particular. The results from our study show the importance of evaluating testing bias in epidemiological studies obtaining data from clinical databases.},
number = {1},
pages = {2},
volume = {7},
year = {2010},
month = {May},
language = {ENG},
date-added = {2010-05-23 11:55:08 +0200},
date-modified = {2010-05-23 11:55:08 +0200},
doi = {10.1186/1742-7622-7-2},
pii = {1742-7622-7-2},
pmid = {20470397},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Velthove-2010-Emerging%20themes%20in%20epidemiology_Testing%20bias%20in%20clin.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11907},
rating = {0}
}

@article{Fan:2001p5596,
author = {X Fan and B Thompson},
journal = {Educational and Psychological Measurement},
title = {Confidence intervals about score reliability coefficients, please: An EPM guidelines editorial},
abstract = {Confidence intervals for reliability coefficients can be estimated in various ways. The present article illustrates a variety of these applications. This guidelines editorial also promulgates a request that EPM authors report confidence intervals for reliability esti- mates whenever they report score reliabilities and note what interval estimation methods they have used. This will reinforce reader understanding that all statistical estimates, including those for score reliability, are affected by sampling error variance. And these requirements may also facilitate understanding that tests are not impregnated with invariant reliability as a routine part of printing.},
number = {4},
pages = {517--531},
volume = {61},
year = {2001},
date-added = {2010-02-12 15:42:12 +0100},
date-modified = {2010-02-12 15:43:29 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Fan-2001-Educational%20and%20Psychological%20Measurement_Confidence%20intervals.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5596},
rating = {0}
}

@article{Levy:2009p542,
author = {Roy Levy and Dubravka Svetina},
title = {A New Statistic and Posterior Predictive Model Checking Procedure for Dimensionality Assessment in Multidimensional Item Response Theory},
abstract = {A generalized dimensionality statistic is introduced to facilitate a critique of dimensionality
assumptions in multidimensional item response models. Connections between dimensionality and local independence motivate the development of the statistic from a conditional covariance theory perspective. A simulation study and a real data analysis demonstrate the utility of the statistic's application at multiple levels of analysis in a posterior predictive model checking framework.},
affiliation = {Arizona State University},
year = {2009},
keywords = {posterior predictive model checking, generalized dimensionality statistic, multidimensional item response theory},
date-added = {2010-01-03 14:12:06 +0100},
date-modified = {2010-01-03 14:13:31 +0100},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Levy-2009-_A%20New%20Statistic%20and.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p542},
rating = {0}
}

@article{Middelberg:2007p2238,
author = {Rita P S Middelberg and Sarah E Medland and Nicholas G Martin and John B Whitfield},
journal = {Twin research and human genetics : the official journal of the International Society for Twin Studies},
title = {A longitudinal genetic study of uric acid and liver enzymes in adolescent twins},
abstract = {Biochemical traits such as plasma alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyltransferase (GGT) and uric acid are associated with obesity, and with risk of cardiovascular disease, metabolic syndrome and diabetes. Each is subject to genetic influences, but little is known about changes in genetic and environmental influences on these traits over time. We investigated the contribution of genetic and environmental influences to variation in these biochemical traits in adolescent twins and their nontwin siblings from 965 twin families. Twins were studied at ages 12, 14 and 16 years. Multivariate genetic models that included effects of age and sex were fitted to determine whether the same or different genetic or environmental factors influence each trait at different ages. Results showed that the genetic factors influencing AST, ALT, GGT and uric acid change over time during adolescence, and that the magnitude of these effects differs between males and females. The nonshared environment effects were generally time specific. There are developmental changes in genes affecting these traits during adolescence.},
affiliation = {Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia. rita.middelberg@qimr.edu.au},
number = {5},
pages = {757--64},
volume = {10},
year = {2007},
month = {Oct},
language = {eng},
keywords = {gamma-Glutamyltransferase, Male, Genetic Variation, Alanine Transaminase, Twins: Monozygotic, Environment, Uric Acid, Multivariate Analysis, Female, Longitudinal Studies, Aspartate Aminotransferases, Twins: Dizygotic, Humans, Adolescent, Liver, Age Factors},
date-added = {2010-01-10 11:59:05 +0100},
date-modified = {2010-01-10 11:59:05 +0100},
doi = {10.1375/twin.10.5.757},
pmid = {17903117},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Middelberg-2007-Twin%20research%20and%20human%20genetics%20the%20official%20journal%20of%20the%20International%20Society%20for%20Twin%20Studies_A%20longitudinal%20genet.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p2238},
rating = {0}
}

@article{Lieber:2000p11163,
author = {E Lieber and K-S Yang},
journal = {Journal of Cross-Cultural Psychology},
title = {An external orientation to the study of causal beliefs. Applications to Chinese populations and comparative research},
number = {2},
pages = {160--186},
volume = {31},
year = {2000},
date-added = {2010-04-25 21:04:23 +0200},
date-modified = {2010-04-25 21:08:22 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Lieber-2000-Journal%20of%20Cross-Cultural%20Psychology_An%20external%20orientat.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p11163},
rating = {0}
}

@article{Yuan:2007p12323,
author = {M Yuan and Y Lin},
journal = {Biometrika},
title = {Model selection and estimation in the Gaussian graphical model},
abstract = {We propose penalized likelihood methods for estimating the concentration matrix in the Gaussian graphical model. The methods lead to a sparse and shrinkage estimator of the concentration matrix that is positive definite, and thus conduct model selection and estimation simultaneously. The implementation of the methods is nontrivial because of the positive definite constraint on the concentration matrix, but we show that the computation can be done effectively by taking advantage of the efficient maxdet algorithm developed in convex optimization. We propose a BIC-type criterion for the selection of the tuning parameter in the penalized likelihood methods. The connection between our methods and existing methods is illustrated. Simulations and real examples demonstrate the competitive performance of the new methods.},
number = {1},
pages = {19--35},
volume = {94},
year = {2007},
date-added = {2010-06-12 09:41:48 +0200},
date-modified = {2010-06-12 09:42:49 +0200},
doi = {10.1093/biomet/asm018},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Yuan-2007-Biometrika_Model%20selection%20and.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12323},
rating = {0}
}

@article{Leinonen:2005p5244,
author = {Raija Leinonen and Jaakko Kaprio and Marja Jylh{\"a} and Asko Tolvanen and Markku Koskenvuo and Eino Heikkinen and Taina Rantanen},
journal = {J Am Geriatr Soc},
title = {Genetic influences underlying self-rated health in older female twins},
abstract = {OBJECTIVES: To examine the genetic and environmental sources of variation in self-rated health (SRH) in older female twins and to explore the roles of morbidity, functional limitation, and psychological well-being as mediators of genetic and environmental effects on SRH. DESIGN: Cross-sectional analysis of twin data. SETTING: Research laboratory. PARTICIPANTS: One hundred two monozygotic and 115 dizygotic female twin pairs aged 63 to 76. MEASUREMENTS: SRH was categorized as good, average, or poor. Morbidity was described using a physician-assessed disease-severity scale together with information about the presence of diabetes mellitus and cancer. Maximal walking speed measured over 10 m was used to assess physical functional limitation; the Mini-Mental State Examination and the Center for Epidemiologic Studies Depression Scale were used to characterize psychological well-being. The contributions of genetic and environmental (defined as familial (shared by siblings) or nonshared (unique to each sibling)) effects were assessed using univariate and multivariate structural equation modeling of twin data. RESULTS: SRH did not have its own specific genetic effect but shared a genetic component in common with the genetic components underlying liability to disease severity, maximal walking speed, and depressive symptoms. It accounted for 64% of the variation in SRH, with environmental effects accounting for the remaining variation. CONCLUSION: The current results suggest that there are no specific genetic effects on SRH but rather that genetic influences on SRH are mediated through genetic influences affecting chronic diseases, functional limitation, and mood.},
affiliation = {Finnish Center for Interdisciplinary Gerontology, Department of Health Sciences, University of Jyv{\"a}skyla{\"a}, Finland. raija.leinonen@sport.jyu.fi},
number = {6},
pages = {1002--7},
volume = {53},
year = {2005},
month = {Jun},
language = {eng},
keywords = {Cross-Sectional Studies, Middle Aged, Finland, Female, Activities of Daily Living, Mental Health, Environment, Depression, Humans, Twins, Aged, Health Status, Self Concept, Diseases in Twins, Logistic Models, Walking, Multivariate Analysis},
date-added = {2010-02-09 22:00:13 +0100},
date-modified = {2010-02-09 22:00:13 +0100},
doi = {10.1111/j.1532-5415.2005.53319.x},
pii = {JGS53319},
pmid = {15935024},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p5244},
rating = {0}
}

@article{Vasic:2008p4288,
author = {Nenad Vasic and Henrik Walter and Annett H{\"o}se and Robert Christian Wolf},
journal = {J Affect Disord},
title = {Gray matter reduction associated with psychopathology and cognitive dysfunction in unipolar depression: a voxel-based morphometry study},
abstract = {BACKGROUND: Functional neuroimaging studies on both cognitive processing and psychopathology in patients with major depression have reported several functionally aberrant brain areas within limbic-cortical circuits. However, less is known about the relationship between psychopathology, cognitive deficits and regional volume alterations in this patient population. METHODS: By means of voxel-based morphometry (VBM) and a standardized neuropsychological test battery, we examined 15 patients meeting DSM-IV criteria for major depression disorder and 14 healthy controls in order to investigate the relationship between affective symptoms, cognitive deficits and structural abnormalities. RESULTS: Patients with depression showed reduced gray matter concentration (GMC) in the left inferior temporal cortex (BA 20), the right orbitofrontal (BA 11) and the dorsolateral prefrontal cortex (BA 46). Reduced gray matter volume (GMV) was found in the left hippocampal gyrus, the cingulate gyrus (BA 24/32) and the thalamus. Structure-cognition correlation analyses revealed that decreased GMC of the right medial and inferior frontal gyrus was associated with both depressive psychopathology and worse executive performance as measured by the Wisconsin Card Sorting Test (WCST). Furthermore, depressive psychopathology and worse performance during the WCST were associated with decreased GMV of the hippocampus. Decreased GMV of the cingulate cortex was associated with worse executive performance. LIMITATIONS: Moderate illness severity, medication effects, and the relatively small patient sample size should be taken into consideration when reviewing the implications of these results. CONCLUSIONS: The volumetric results indicate that regional abnormalities in gray matter volume and concentration may be associated with both psychopathological changes and cognitive deficits in depression.},
affiliation = {Department of Psychiatry III, University of Ulm, Leimgrubenweg 12-14, 89075 Ulm, Germany. nenad.vasic@uni-ulm.de},
number = {1-2},
pages = {107--16},
volume = {109},
year = {2008},
month = {Jul},
language = {eng},
keywords = {Cognition Disorders, Prefrontal Cortex, Neuropsychological Tests, Magnetic Resonance Imaging, Severity of Illness Index, Male, Brief Psychiatric Rating Scale, Female, Adult, Depressive Disorder, Humans, Diagnostic and Statistical Manual of Mental Disorders},
date-added = {2010-01-25 20:29:07 +0100},
date-modified = {2010-01-25 20:29:07 +0100},
doi = {10.1016/j.jad.2007.11.011},
pii = {S0165-0327(07)00399-0},
pmid = {18191459},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p4288},
rating = {0}
}

@article{Leclerc:2005p12052,
author = {H Leclerc and W F Fikse and V Ducrocq},
journal = {Journal of Dairy Science},
title = {Principal Components and Factorial Approaches for Estimating
Genetic Correlations in International Sire Evaluation},
abstract = {The increasing number of participating countries and the lack of genetic links among some of them lead to statistical and computational difficulties in estimating the genetic (co)variance matrix needed for international sire evaluation of milk yield. Reparameterization using principal components or factorial approaches is pro- posed to exploit patterns in the genetic correlation ma- trix in order to reduce the number of parameters to be estimated without much loss of information. A 2-step approach was used. First, the genetic matrix between 8 or 9 ``base'' countries was used to determine a reduced number of principal components or factors. Then, the contributions of the remaining countries to these princi- pal components or factors were computed. The resulting genetic correlations for the 18 countries were compared with the ``reference'' genetic correlations obtained with a classical model. The impact of using reparameterized genetic correlation matrices on breeding value predic- tion was investigated for both approaches. A better agreement between predicted breeding values and sta- bility of their rankings was found when an approximate factor analysis was used, whatever the number of fac- tors considered. The estimation of genetic correlations among 18 countries using an approximate factorial ap- proach with 5 factors taken into account led to a reduc- tion of the number of parameters to estimate from 171 to 80. The average absolute deviation of the correlations estimated with an approximate factorial approach from the ``reference'' genetic correlations was 0.014, which is considered very satisfactory in light of the computa- tional ease.},
pages = {3306--3315},
volume = {88},
year = {2005},
date-added = {2010-05-24 10:36:57 +0200},
date-modified = {2010-05-24 10:37:51 +0200},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Leclerc-2005-Journal%20of%20Dairy%20Science_Principal%20Components.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p12052},
rating = {0}
}

@article{Wong:2008p7575,
author = {Chloe C Y Wong and Gunter Schumann},
journal = {Philos Trans R Soc Lond, B, Biol Sci},
title = {Review. Genetics of addictions: strategies for addressing heterogeneity and polygenicity of substance use disorders},
abstract = {Addictions are common psychiatric disorders that exert high cost to the individual and to society. Addictions are a result of the interplay of multiple genetic and environmental factors. They are characterized by phenotypic and genetic heterogeneity as well as polygenicity, implying a contribution of different neurobiological mechanisms to the clinical diagnosis. Therefore, treatments for most substance use disorders are often only partially effective, with a substantial proportion of patients failing to respond. To address heterogeneity and polygenicity, strategies have been developed to identify more homogeneous subgroups of patients and to characterize genes contributing to their phenotype. These include genetic linkage and association studies as well as functional genetic analysis using endophenotypes and animal behavioural experimentation. Applying these strategies in a translational context aims at improving therapeutic response by the identification of subgroups of addiction patients for individualized, targeted treatment strategies. This article aims to discuss strategies addressing heterogeneity and polygenicity of substance use disorders by presenting results of recent research on genetic and environmental components of addiction. It will also introduce the European IMAGEN study that aims to integrate methodical approaches discussed in order to identify the genetic and neurobiological basis of behavioural traits relevant to the development of addictions.},
affiliation = {Interdisciplinary Research Group Addiction, MRC-SGDP-Centre, Institute of Psychiatry at King's College, London, 16 De Crespigny Park, London SE5 8AF, UK.},
number = {1507},
pages = {3213--22},
volume = {363},
year = {2008},
month = {Oct},
language = {eng},
keywords = {Inheritance Patterns, Multifactorial Inheritance, Substance-Related Disorders, Phenotype, Corticotropin-Releasing Hormone, Genomics, Humans, Linkage (Genetics), Genetic Heterogeneity, Genetic Variation, Stress: Psychological},
date-added = {2010-03-14 11:04:05 +0100},
date-modified = {2010-03-14 11:04:06 +0100},
doi = {10.1098/rstb.2008.0104},
pii = {4804031Q83TH275J},
pmid = {18640915},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Wong-2008-Philos%20Trans%20R%20Soc%20Lond%20B%20Biol%20Sci_Review.%20Genetics%20of.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p7575},
rating = {3}
}

@article{Pournara:2007p874,
author = {Iosifina Pournara and Lorenz Wernisch},
journal = {BMC Bioinformatics},
title = {Factor analysis for gene regulatory networks and transcription factor activity profiles},
abstract = {BACKGROUND: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription factors (TFs) are proportional to their mRNA levels. This assumption is invalid for most biological systems. However, one might be able to reconstruct unobserved activity profiles of TFs from the expression profiles of target genes. A simple model is a two-layer network with unobserved TF variables in the first layer and observed gene expression variables in the second layer. TFs are connected to regulated genes by weighted edges. The weights, known as factor loadings, indicate the strength and direction of regulation. Of particular interest are methods that produce sparse networks, networks with few edges, since it is known that most genes are regulated by only a small number of TFs, and most TFs regulate only a small number of genes. RESULTS: In this paper, we explore the performance of five factor analysis algorithms, Bayesian as well as classical, on problems with biological context using both simulated and real data. Factor analysis (FA) models are used in order to describe a larger number of observed variables by a smaller number of unobserved variables, the factors, whereby all correlation between observed variables is explained by common factors. Bayesian FA methods allow one to infer sparse networks by enforcing sparsity through priors. In contrast, in the classical FA, matrix rotation methods are used to enforce sparsity and thus to increase the interpretability of the inferred factor loadings matrix. However, we also show that Bayesian FA models that do not impose sparsity through the priors can still be used for the reconstruction of a gene regulatory network if applied in conjunction with matrix rotation methods. Finally, we show the added advantage of merging the information derived from all algorithms in order to obtain a combined result. CONCLUSION: Most of the algorithms tested are successful in reconstructing the connectivity structure as well as the TF profiles. Moreover, we demonstrate that if the underlying network is sparse it is still possible to reconstruct hidden activity profiles of TFs to some degree without prior connectivity information.},
affiliation = {School of Crystallography, Birkbeck College, University of London, London, UK. i.pournara@cryst.bbk.ac.uk},
pages = {61},
volume = {8},
year = {2007},
month = {Jan},
language = {eng},
keywords = {Transcription Factors, Oligonucleotide Array Sequence Analysis, Transcriptional Activation, Computer Simulation, Signal Transduction, Gene Expression Profiling, Models: Genetic, Bayes Theorem, Gene Expression Regulation, Algorithms, Factor Analysis: Statistical},
date-added = {2010-01-03 18:08:53 +0100},
date-modified = {2010-03-03 19:39:26 +0100},
doi = {10.1186/1471-2105-8-61},
pii = {1471-2105-8-61},
pmid = {17319944},
local-url = {file://localhost/Users/chl/Dropbox/Papers/Pournara-2007-BMC%20Bioinformatics_Factor%20analysis%20for.pdf},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p874},
rating = {3}
}

@article{Bizzarri:2007p13040,
author = {Jacopo V Bizzarri and Alfredo Sbrana and Paola Rucci and Laura Ravani and Guido Jacopo Massei and Chiara Gonnelli and Sabrina Spagnolli and Maria Rosa Doria and Federica Raimondi and Jean Endicott and Liliana Dell'Osso and Giovanni Battista Cassano},
journal = {Bipolar Disord},
title = {The spectrum of substance abuse in bipolar disorder: reasons for use, sensation seeking and substance sensitivity},
abstract = {OBJECTIVES: To examine the spectrum of alcohol and substance abuse, including reasons for use, in patients with bipolar I disorder, compared with patients with substance use disorder and healthy controls, with a specific focus on the relationship between substance use, substance sensitivity, other comorbid psychiatric symptoms and traits related to sensation seeking. METHODS: This study included 104 patients with bipolar I disorder (BPD I), of whom 57 (54.8%) met DSM-IV criteria for lifetime alcohol or substance use disorder (BPD + SUD), 35 patients with substance use disorder (SUD) and no psychiatric disorder and 50 healthy controls. Assessments included the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) and the Structured Clinical Interview for the Spectrum of Substance Use (SCI-SUBS). RESULTS: Patients with BPD + SUD and SUD had significantly higher scores on the SCI-SUBS domains of self-medication, substance sensitivity and sensation seeking compared with patients with BPD and healthy controls. Reasons for substance use did not differ between patients with BPD + SUD and patients with SUD. Those most frequently cited were: improving mood; relieving tension; alleviating boredom; achieving/maintaining euphoria; and increasing energy. CONCLUSIONS: Recourse to substances is associated with increased mood and anxiety symptoms, substance sensitivity, and sensation seeking among patients with BPD + SUD and SUD. Substance sensitivity and sensation seeking traits should be investigated in all patients with BPD as possible factors associated with a development of SUD, in order to warn patients of the specific risks related to improper use of medications and substances.},
affiliation = {Drug Addiction Service, Bolzano, Italy.},
number = {3},
pages = {213--20},
volume = {9},
year = {2007},
month = {May},
language = {eng},
keywords = {Substance-Related Disorders, Male, Exploratory Behavior, Diagnostic and Statistical Manual of Mental Disorders, Boredom, Severity of Illness Index, Comorbidity, Adult, Female, Self Medication, Humans, Antipsychotic Agents, Prevalence, Bipolar Disorder, Anxiety Disorders},
date-added = {2010-06-25 22:38:39 +0200},
date-modified = {2010-06-25 22:38:40 +0200},
doi = {10.1111/j.1399-5618.2007.00383.x},
pii = {BDI383},
pmid = {17430295},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13040},
rating = {0}
}

@article{Gao:2010p3115,
author = {Xiaoyi Gao and Lewis C Becker and Diane M Becker and Joshua D Starmer and Michael A Province},
journal = {Genet Epidemiol},
title = {Avoiding the high Bonferroni penalty in genome-wide association studies},
abstract = {A major challenge in genome-wide association studies (GWASs) is to derive the multiple testing threshold when hypothesis tests are conducted using a large number of single nucleotide polymorphisms. Permutation tests are considered the gold standard in multiple testing adjustment in genetic association studies. However, it is computationally intensive, especially for GWASs, and can be impractical if a large number of random shuffles are used to ensure accuracy. Many researchers have developed approximation algorithms to relieve the computing burden imposed by permutation. One particularly attractive alternative to permutation is to calculate the effective number of independent tests, M(eff), which has been shown to be promising in genetic association studies. In this study, we compare recently developed M(eff) methods and validate them by the permutation test with 10,000 random shuffles using two real GWAS data sets: an Illumina 1M BeadChip and an Affymetrix GeneChip Human Mapping 500K Array Set. Our results show that the simpleM method produces the best approximation of the permutation threshold, and it does so in the shortest amount of time. We also show that M(eff) is indeed valid on a genome-wide scale in these data sets based on statistical theory and significance tests. The significance thresholds derived can provide practical guidelines for other studies using similar population samples and genotyping platforms.},
affiliation = {Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO 63108, USA. ray.x.gao@gmail.com},
number = {1},
pages = {100--5},
volume = {34},
year = {2010},
month = {Jan},
language = {eng},
date-added = {2010-01-14 20:21:36 +0100},
date-modified = {2010-01-14 20:21:38 +0100},
doi = {10.1002/gepi.20430},
pmid = {19434714},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p3115},
rating = {3}
}

@article{Allen:2005,
author = {A S Allen and H X Barnhart},
journal = {Journal of Data Science},
title = {General marginal regression models for the joint modeling of event frequency and correlated severities with applications to clinical trials},
abstract = {In many clinical trials, information is collected on both the fre- quency of event occurrence and the severity of each event. For example, in evaluating a new anti-epileptic medication both the total number of seizures a patient has during the study period as well as the severity (e.g., mild, severe) of each seizure could be measured. In order to arrive at a full picture of drug or treatment performance, one needs to jointly model the number of events and their correlated ordinal severity measures. A separate analysis is not recommended as it is inefficient and can lead to what we define as ``zero length bias'' in estimates of treatment effect on severity. This paper proposes a general, likelihood based, marginal regression model for jointly modeling the number of events and their correlated ordinal severity measures. We de- scribe parameter estimation issues and derive the Fisher information matrix for the joint model in order to obtain the asymptotic covariance matrix of the parameter estimates. A limited simulation study is conducted to exam- ine the asymptotic properties of the maximum likelihood estimators. Using this joint model, we propose tests that incorporate information from both the number of events and their correlated ordinal severity measures. The methodology is illustrated with two examples from clinical trials: the first concerning a new drug treatment for epilepsy; the second evaluating the effect of a cholesterol lowering medication on coronary artery disease.},
pages = {199--219},
volume = {3},
year = {2005},
date-added = {2010-01-03 19:38:21 +0100},
date-modified = {2010-01-03 19:38:22 +0100},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p1135},
read = {Yes},
rating = {0}
}

@article{Nuevo:2009p13795,
author = {Roberto Nuevo and Graham Dunn and Christopher Dowrick and Jos{\'e} Luis V{\'a}zquez-Barquero and Patricia Casey and Odd Stefen Dalgard and Ville Lehtinen and Jos{\'e} Luis Ayuso-Mateos},
journal = {J Affect Disord},
title = {Cross-cultural equivalence of the Beck Depression Inventory: a five-country analysis from the ODIN study},
abstract = {BACKGROUND: The Beck Depression Inventory (BDI) has demonstrated excellent psychometric properties and good performance as a screening measure in different contexts and languages. However, comparison of its structure across countries and languages remains understudied. Measurement invariance is a prerequisite for considering the BDI equivalent across versions, and for using it to make valid and interpretable comparisons of the severity of depression among different groups. METHODS: As part of a five-country (UK, Ireland, Spain, Norway, and Finland), two-stage epidemiological study of depressive disorder, 7934 persons were screened using the BDI. The item equivalence and measurement invariance of the BDI across the samples of the five countries was tested using Item Response Theory (IRT) and Multiple Indicators Multiple Causes (MIMIC) models. RESULTS: Overall results support the factorial validity of the BDI, with a unidimensional structure. Item 19 (weight loss) presented a clear misfit in the five countries. IRT models, as well as MIMIC models, suggest that complete measurement invariance cannot be assumed across the five countries. The Spanish sample accounted for the majority of the differences, with a moderate to low Differential Item Functioning for the other countries on the different items. CONCLUSIONS: The BDI could be used cross-culturally in Europe, with particular cautions regarding the Spanish sample, and with the constraints and limits pointed out for the present results. The methodology used for the present work is suggested as a soundness approach for testing the cross-cultural validity of severity rating scales.},
affiliation = {Department of Psychiatry, Aut{\'o}noma University of Madrid, La Princesa University Hospital, Madrid, Spain.},
number = {1-3},
pages = {156--62},
volume = {114},
year = {2009},
month = {Apr},
language = {eng},
keywords = {Finland, Ireland, Cross-Cultural Comparison, Severity of Illness Index, Norway, Reference Values, Spain, Reproducibility of Results, Questionnaires, Psychometrics, Humans, Great Britain, Psychiatric Status Rating Scales, Factor Analysis: Statistical, Depressive Disorder},
date-added = {2010-07-29 12:18:11 +0200},
date-modified = {2010-07-29 12:18:11 +0200},
doi = {10.1016/j.jad.2008.06.021},
pii = {S0165-0327(08)00278-4},
pmid = {18684511},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p13795},
rating = {0}
}

@article{Stein:2010p9781,
author = {Jason L Stein and Xue Hua and Suh Lee and April J Ho and Alex D Leow and Arthur W Toga and Andrew J Saykin and Li Shen and Tatiana Foroud and Nathan Pankratz and Matthew J Huentelman and David W Craig and Jill D Gerber and April N Allen and Jason J Corneveaux and Bryan M Dechairo and Steven G Potkin and Michael W Weiner and Paul M Thompson and the Alzheimer's Disease Neuroimaging Initiative},
journal = {Neuroimage},
title = {Voxelwise genome-wide association study (vGWAS)},
abstract = {The structure of the human brain is highly heritable, and is thought to be influenced by many common genetic variants, many of which are currently unknown. Recent advances in neuroimaging and genetics have allowed collection of both highly detailed structural brain scans and genome-wide genotype information. This wealth of information presents a new opportunity to find the genes influencing brain structure. Here we explore the relation between 448,293 single nucleotide polymorphisms in each of 31,622 voxels of the entire brain across 740 elderly subjects (mean age+/-s.d.: 75.52+/-6.82 years; 438 male) including subjects with Alzheimer's disease, Mild Cognitive Impairment, and healthy elderly controls from the Alzheimer's Disease Neuroimaging Initiative (ADNI). We used tensor-based morphometry to measure individual differences in brain structure at the voxel level relative to a study-specific template based on healthy elderly subjects. We then conducted a genome-wide association at each voxel to identify genetic variants of interest. By studying only the most associated variant at each voxel, we developed a novel method to address the multiple comparisons problem and computational burden associated with the unprecedented amount of data. No variant survived the strict significance criterion, but several genes worthy of further exploration were identified, including CSMD2 and CADPS2. These genes have high relevance to brain structure. This is the first voxelwise genome wide association study to our knowledge, and offers a novel method to discover genetic influences on brain structure.},
affiliation = {Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles School of Medicine, Neuroscience Research Building 225E, 635 Charles Young Drive, Los Angeles, CA 90095-1769, USA.},
pages = {},
year = {2010},
month = {Feb},
language = {ENG},
date-added = {2010-03-26 19:19:48 +0100},
date-modified = {2010-03-26 19:20:02 +0100},
doi = {10.1016/j.neuroimage.2010.02.032},
pii = {S1053-8119(10)00200-4},
pmid = {20171287},
uri = {papers://58407365-8DEB-4C7D-995B-6322E39C7022/Paper/p9781},
rating = {5}
}

@article{Levin:2009p13249,
author = {Kate A Levin and Candace Currie and Janine Muldoon},
journal = {Eur J Public Health},
title = {Mental well-being and subjective health of 11- to 15-year-old boys and girls in Scotland, 1994-2006},
abstract = {BACKGROUND: Promoting young people's mental well-being and reducing socioeconomic inequalities are priority areas for WHO and the Scottish Government. This article describes changes in the subjective health and mental well-being of adolescents living in Scotland between 1994 and 2006, and investigates socioeconomic inequalities in mental well-being and subjective health over time. METHODS: Data from the 1994, 1998, 2002 and 2006 Health Behaviour in School-aged Children surveys were analysed using Multilevel Binomial modelling. RESULTS: Boys and younger adolescents scored more favourably on measures of confidence, happiness, helplessness and feeling left out than girls and older adolescents. Multiple

license: MIT

license_type: permissive

branch_name: refs/heads/master

extension: bib