Datasets:
key string | id string | source string | pmid string | pmcid string | doi string | title string | abstract string | authors list | author_string string | journal string | year int64 | first_publication_date timestamp[s] | pub_types list | language string | mesh list | keywords list | grants list | is_open_access bool | in_epmc bool | in_pmc bool | has_pdf bool | license string | cited_by_count int64 | fulltext_urls list | tiers list | retrieved_at timestamp[s] | raw_page string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PPR:PPR1320864 | PPR1320864 | PPR | null | null | 10.64898/2026.09.09.750505 | Sex-dimorphic immune trajectories across the canine lifespan and early-life signatures of geroprotective interventions | Canine models are invaluable for translational geroscience, but widespread gonadectomy in companion dogs obscures natural sex-specific aging trajectories. Here, we characterize the age-associated hematologic and serum cytokine profiles of 80 intact laboratory Beagles spanning 1 to 11 years. Contrary to classical linear... | [
"Lai M",
"Xu F",
"Xu Y",
"Mironenkov A",
"Jin Y",
"Zhang S",
"Pan J",
"Li M",
"Deng B",
"Zhu J",
"Lyu Y"
] | Lai M, Xu F, Xu Y, Mironenkov A, Jin Y, Zhang S, Pan J, Li M, Deng B, Zhu J, Lyu Y. | null | 2,026 | 2026-09-15T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.09.09.750505"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1320229 | PPR1320229 | PPR | null | null | 10.20944/preprints202609.1190.v1 | Longitudinal Changes in Redox-, Immune-, and Neuroendocrine-Related Biomarkers During Low-Intensity Multi-Frequency Bioelectronic Stimulation in Aged Dogs: An Exploratory Pilot Study | Aging is associated with chronic low-grade inflammation, redox imbalance, and altered neuroendocrine regulation. This exploratory pilot study evaluated the feasibility, safety, and longitudinal biomarker changes observed during low-intensity multi-frequency bioelectronic stimulation in six clinically healthy aged dogs ... | [
"Yoo E",
"Choi Y",
"You E"
] | Yoo E, Choi Y, You E. | null | 2,026 | 2026-09-15T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.20944/preprints202609.1190.v1"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1301854 | PPR1301854 | PPR | null | null | 10.21203/rs.3.rs-10652184/v1 | Title page: Pharmacokinetics of Cefovecin (Convenia®) After 8 mg/kg Intramuscular Administration in Bottlenose Dolphins (Tursiops truncatus): Age-Related Differences | <title>Abstract</title> <p> · <bold>Background:</bold> Cefovecin is a third-generation cephalosporin approved for use in dogs and cats, characterized by an exceptionally long elimination half-life that in these species allows for a 14-day dosing interval. This pharmacological profile makes it particularly attractiv... | [
"Encinas T",
"Morón-Elorza P",
"Rojo-Solís C",
"Álvaro T",
"Valls M",
"Gilabert JA",
"García-Párraga D"
] | Encinas T, Morón-Elorza P, Rojo-Solís C, Álvaro T, Valls M, Gilabert JA, García-Párraga D. | null | 2,026 | 2026-08-20T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.21203/rs.3.rs-10652184/v1"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1286822 | PPR1286822 | PPR | null | null | 10.20944/preprints202607.1962.v1 | Magnetic Resonance Imaging as a Diagnostic Marker of CCD: A Review | Alzheimer’s disease (AD) in humans shares several features with canine cognitive dysfunction (CCD), a disease that affects older dogs. Therefore, CCD serves as a natural model for the study of AD. Several studies have documented early pathological changes in both AD and CCD, including widespread damage to the cerebral ... | [
"Garcia MSA",
"Anaya JSH",
"Santoscoy Mejia EC",
"Mendez Aguilar RE"
] | Garcia MSA, Anaya JSH, Santoscoy Mejia EC, Mendez Aguilar RE. | null | 2,026 | 2026-07-28T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.20944/preprints202607.1962.v1"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1279057 | PPR1279057 | PPR | null | null | 10.64898/2026.07.11.737944 | A canine brain bank for comparative neuroscience and brain aging research | Companion animal brain banking has been recognized as a valuable approach for translational aging and dementia research. However, realizing the full value of canine brain banks depends on optimizing the methods that are used to collect and preserve the tissue. Whole brain perfusion fixation is one promising approach, b... | [
"Darcy S",
"Beck A",
"Garrood M",
"Slaughter A",
"Parra A",
"Paredes L",
"Farrell K",
"Crary JF",
"McKenzie AT"
] | Darcy S, Beck A, Garrood M, Slaughter A, Parra A, Paredes L, Farrell K, Crary JF, McKenzie AT. | null | 2,026 | 2026-07-14T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.07.11.737944"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1245910 | PPR1245910 | PPR | null | null | 10.64898/2026.06.03.729926 | An interpretable machine learning framework for dog breed inference and ancestry decomposition | The over 300 currently recognized breeds of domesticated dogs are the culmination of centuries of intense artificial selection and recurrent population bottlenecks. While breed labels are widely used in genetic and veterinary studies, inferring breed identity from genomic data remains challenging due to the high dimens... | [
"Bian Y",
"Bierman R",
"Snyder-Mackler N",
"Promislow D",
"Karlsson E",
"",
"Akey JM"
] | Bian Y, Bierman R, Snyder-Mackler N, Promislow D, Karlsson E, Dog Aging Project Consortium, Akey JM. | null | 2,026 | 2026-06-04T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.06.03.729926"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1244197 | PPR1244197 | PPR | null | null | 10.64898/2026.06.01.729193 | NECAP antagonizes light-induced Rhodopsin-1 internalization to promote photoreceptor homeostasis | AP-2 is a key mediator of clathrin-mediated endocytosis (CME) that internalizes cargo from the plasma membrane. NECAP proteins physically bind phosphorylated AP-2 during CME, but their roles during endocytosis remain unresolved, with conflicting reports about their function. Here, we report that Drosophila NECAP is di... | [
"Huang H",
"Tyrlik M",
"Huang P",
"Yeo AI",
"Kim A",
"Perrimon N",
"Tseng C",
"Bellen HJ",
"Ryoo HD"
] | Huang H, Tyrlik M, Huang P, Yeo AI, Kim A, Perrimon N, Tseng C, Bellen HJ, Ryoo HD. | null | 2,026 | 2026-06-02T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.06.01.729193"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1224166 | PPR1224166 | PPR | null | null | 10.64898/2026.02.10.705136 | Thermodynamic scaling of canine aging and reversible clock deceleration by a reverse transcriptase inhibitor | Aging was tracked in a cohort of 99 “retired” sled dogs over four years to characterize the latent dynamics of physiological decline. Animals were randomized to receive either placebo or the reverse transcriptase inhibitor lamivudine for ∼30 months. We employed a variational autoregressive model to integrate longitudin... | [
"Matrenok S",
"Andrianova EL",
"Avchaciov K",
"Fleyshman DI",
"Huson HJ",
"Loftus JP",
"Wakshlag JJ",
"Zhang B",
"Gladyshev VN",
"Gudkov AV",
"Fedichev PO"
] | Matrenok S, Andrianova EL, Avchaciov K, Fleyshman DI, Huson HJ, Loftus JP, Wakshlag JJ, Zhang B, Gladyshev VN, Gudkov AV, Fedichev PO. | null | 2,026 | 2026-02-12T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 2 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.02.10.705136"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1222924 | PPR1222924 | PPR | null | null | 10.64898/2026.02.19.706838 | Beyond dual hubs: Task and aging shape taxonomic and thematic semantic relationships in the human brain | Semantic knowledge about concepts and their relationships is central to human cognition. Taxonomic relationships link concepts belonging to the same category (e.g. dog and bear ), while thematic relationships connect concepts co-occurring in the same events (e.g. dog and leash ). The dual-hub theory proposes that t... | [
"Kuhnke P",
"Martin S",
"Chapman CA",
"Hartwigsen G"
] | Kuhnke P, Martin S, Chapman CA, Hartwigsen G. | null | 2,026 | 2026-02-20T00:00:00 | [
"Preprint"
] | null | [] | [] | [
{
"grant_id": "101043747",
"agency": "European Research Council",
"acronym": null
},
{
"grant_id": "FLEXBRAIN, ERC-COG-2021-101043747",
"agency": "European Research Council",
"acronym": "ERC_"
},
{
"grant_id": "HA 6314/4-2",
"agency": "Deutsche Forschungsgemeinschaft",
"a... | true | true | false | true | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.02.19.706838"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/article/PPR/PPR1222924"
},
{
"site": "Europe_PMC",
"availability":... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1217675 | PPR1217675 | PPR | null | null | 10.64898/2026.03.07.710297 | Blood biomarkers and breed genetics of aging in pet dogs | Pet dogs share human-like environments while aging on a compressed timescale, making them a powerful translational model for aging research. Using genomic and phenotypic data from 7,627 dogs in the Dog Aging Project, including 976 profiled for 159 blood metabolites and clinical analytes, we generated the first GWAS cat... | [
"Sohrab V",
"White ME",
"Harrison BR",
"Bierman R",
"Marye A",
"Morrill Pirovich K",
"Genereux DP",
"Megquier K",
"Li X",
"Kenney B",
"Reichel C",
"",
"Snyder-Mackler N",
"Akey JM",
"Promislow DEL",
"Chen FL",
"Karlsson EK"
] | Sohrab V, White ME, Harrison BR, Bierman R, Marye A, Morrill Pirovich K, Genereux DP, Megquier K, Li X, Kenney B, Reichel C, Dog Aging Project Consortium, Snyder-Mackler N, Akey JM, Promislow DEL, Chen FL, Karlsson EK. | null | 2,026 | 2026-03-10T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.03.07.710297"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1214553 | PPR1214553 | PPR | null | null | 10.64898/2026.04.14.718346 | Stem Cell Divisions, Driver Mutations, and Carcinogenesis in Purebred Dogs | Most cancers are initiated by mutations that inactivate tumour-suppressor genes or activate oncogenes. Fitting a multistage model of carcinogenesis to the increase in cancer mortality with breed-specific size and lifespan in dogs has predicted that four somatic driver mutations are typically required to initiate cancer... | [
"da Silva J"
] | da Silva J. | null | 2,026 | 2026-04-17T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.64898/2026.04.14.718346"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1182742 | PPR1182742 | PPR | null | null | 10.21203/rs.3.rs-9360671/v1 | Cognitive Assessment for Neuropsychological Impairments in Dogs (CANID): An Efficient, Repeatable, and Sensitive Evaluation for Age-related Cognitive Dysfunction | <title>Abstract</title> <p>We introduce the Cognitive Assessment for Neuropsychological Impairments in Dogs (CANID), a functional evaluation consisting of three cognitive tasks that measure aspects of memory and executive function. CANID can be implemented in a single ~ 40-minute evaluation, was designed for studies o... | [
"Hargrave SH",
"Bray EE",
"Switzer LR",
"McGrath S",
"Alexander GE",
"Block T",
"Carranza E",
"Chao N",
"Douglas LELC",
"Galante J",
"Hilyard E",
"Jonkoski D",
"Kennedy BS",
"Kristal E",
"Moreno JA",
"Promislow DEL",
"Raichlen DA",
"Stetson N",
"Tereso K",
"Vogel N",
"",
"M... | Hargrave SH, Bray EE, Switzer LR, McGrath S, Alexander GE, Block T, Carranza E, Chao N, Douglas LELC, Galante J, Hilyard E, Jonkoski D, Kennedy BS, Kristal E, Moreno JA, Promislow DEL, Raichlen DA, Stetson N, Tereso K, Vogel N, The Dog Aging Project Consortium, MacLean EL. | null | 2,026 | 2026-04-27T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.21203/rs.3.rs-9360671/v1"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1177788 | PPR1177788 | PPR | null | null | 10.20944/preprints202604.0902.v1 | Clinical Course of Severe Perineal Hypospadias with Cryptorchid Testicular Tumors in a Dog: Contextual Reference to Developmental and Endocrine Transcriptomic Pathways | Hypospadias is a congenital malformation of the male external genitalia resulting from incomplete fusion of the urethral folds during embryonic development. The perineal form represents the most severe phenotype and is frequently associated with abnormalities such as cryptorchidism and penile hypoplasia. Although surgi... | [
"Lee N",
"Kwon K",
"Oh A",
"Choi K"
] | Lee N, Kwon K, Oh A, Choi K. | null | 2,026 | 2026-04-14T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.20944/preprints202604.0902.v1"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1165397 | PPR1165397 | PPR | null | null | 10.21203/rs.3.rs-8918755/v1 | Senior Dogs have Less Plasma Circulating Exosomes Than Young Dogs, With Altered Sterol and miRNA content | <title>Abstract</title> <p>Increasing life expectancy has been accompanied by a higher prevalence of age-associated conditions, underscoring the need to better understand biological mechanisms of aging and to identify accessible biomarkers. Extracellular vesicles (EVs) are lipid-bilayer vesicles that mediate intercell... | [
"Marina CL",
"Greuel AM",
"Las-Casas LdO",
"Lopes E",
"Ferrari SSdAR",
"Rodrigues ML",
"Reis FCGd",
"Bocca AL",
"Titze-de-Almeida SS",
"Resende FFB",
"de Sant’Anna FJ",
"Titze-de-Almeida R"
] | Marina CL, Greuel AM, Las-Casas LdO, Lopes E, Ferrari SSdAR, Rodrigues ML, Reis FCGd, Bocca AL, Titze-de-Almeida SS, Resende FFB, de Sant’Anna FJ, Titze-de-Almeida R. | null | 2,026 | 2026-03-13T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.21203/rs.3.rs-8918755/v1"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1161338 | PPR1161338 | PPR | null | null | 10.21203/rs.3.rs-8994620/v1 | Alzheimer’s Disease Neuropathological characterization of the dog brain and relationship to biofluid biomarkers and cognitive function | <title>Abstract</title> <p>Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and a major global health challenge affecting more than 55 million people worldwide. AD is clinically defined by progressive cognitive decline and neuropathologically characterized by the accumulation of amyloid... | [
"Alsulami A",
"Bogdani M",
"MacLean E",
"Keene CD",
"McGrath S",
"",
"Latimer CS",
"Moreno JA"
] | Alsulami A, Bogdani M, MacLean E, Keene CD, McGrath S, Dog Aging Project Consortium, Latimer CS, Moreno JA. | null | 2,026 | 2026-03-03T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.21203/rs.3.rs-8994620/v1"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1160523 | PPR1160523 | PPR | null | null | 10.31234/osf.io/qwb6h_v3 | Rethinking Delay of Gratification: Developmental Changes in Self-Regulation Across Five Countries | <p>The ability to delay gratification (DoG) is widely regarded as a hallmark of self-regulation and has been linked to positive developmental and health outcomes. It remains unclear whether age-related improvements in DoG reflect delay-specific control processes or broader developmental changes in children’s regulation... | [
"Zupan Z",
"Gao Z",
"Ranc P",
"Pascu DS",
"Lorenzato L",
"Machado A",
"Oberschulte J"
] | Zupan Z, Gao Z, Ranc P, Pascu DS, Lorenzato L, Machado A, Oberschulte J. | null | 2,026 | 2026-02-28T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.31234/osf.io/qwb6h_v3"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
PPR:PPR1158262 | PPR1158262 | PPR | null | null | 10.21203/rs.3.rs-8895010/v1 | Pilot study on calculus removal from orthodontic retainers using different mechanical approaches: an in-vitro investigation of the adhesive strength of fixed retainers | <title>Abstract</title> <p> <bold>Introduction</bold> Orthodontic fixed retainers are often a predilection site for calculus build-up. However, standardized protocol for professional mechanical plaque removal (PMPR) does not yet exist that takes into account the slight weakening of the adhesive bond. <bold>Material... | [
"Heberer M",
"Pfaff MS",
"Erber R",
"Roser CJ",
"Awounvo S",
"Zenthöfer A",
"Lux CJ",
"Bartha V"
] | Heberer M, Pfaff MS, Erber R, Roser CJ, Awounvo S, Zenthöfer A, Lux CJ, Bartha V. | null | 2,026 | 2026-02-24T00:00:00 | [
"Preprint"
] | null | [] | [] | [] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "F",
"style": "doi",
"url": "https://doi.org/10.21203/rs.3.rs-8895010/v1"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0006.json |
MED:42816925 | 42816925 | MED | 42816925 | null | 10.1177/13872877261491819 | Clinical and neuropathological aspects of canine cognitive dysfunction syndrome and a translational perspective for Alzheimer's disease. | Canine cognitive dysfunction syndrome (CCDS) shares notable clinical and molecular similarities with Alzheimer's disease (AD), supporting the value of cross-species translational research to enhance diagnostic and therapeutic approaches for both conditions. These disorders are progressive neurological diseases characte... | [
"Lopes-Gomes E",
"Resende FFB",
"Greuel AM",
"Marina CL",
"de Sant'Ana FJF",
"Titze-de-Almeida SS",
"Titze-de-Almeida R"
] | Lopes-Gomes E, Resende FFB, Greuel AM, Marina CL, de Sant'Ana FJF, Titze-de-Almeida SS, Titze-de-Almeida R. | Journal of Alzheimer's disease : JAD | 2,026 | 2026-09-30T00:00:00 | [
"IM",
"Review",
"Journal Article"
] | eng | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1177/13872877261491819"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42816321 | 42816321 | MED | 42816321 | null | 10.1292/jvms.26-0189 | Age distribution and regression-associated immunophenotypic features in canine cutaneous histiocytoma. | Canine cutaneous histiocytoma (CCH) is a benign tumor characterized by spontaneous immune-mediated regression. Although common in young dogs, it also occurs in older animals. This retrospective study evaluated histologic and immunohistochemical features of CCH across age groups, focusing on mitotic count, lymphocytic i... | [
"Chen YM",
"Liao ZW",
"Kuo CL",
"Kuo CC",
"Huang WH"
] | Chen YM, Liao ZW, Kuo CL, Kuo CC, Huang WH. | The Journal of veterinary medical science | 2,026 | 2026-10-01T00:00:00 | [
"IM",
"Journal Article"
] | eng | [] | [] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1292/jvms.26-0189"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42808498 | 42808498 | MED | 42808498 | null | 10.1177/13872877261487575 | Aging dogs exhibit heterogeneous cognitive decline trajectories: A longitudinal comparative model. | BackgroundBoth dogs and humans experience substantially variable cognitive decline with age. In humans, this ranges from healthy cognitive aging to early onset Alzheimer's disease. While different rates of cognitive decline have been described in purpose-bred beagles, few studies have examined longitudinal trajectories... | [
"Simon KE",
"Panek WK",
"Fefer G",
"Mondino A",
"Yang CC",
"Rafatpanah Baigi S",
"Khan MZ",
"Case BC",
"Griffith E",
"Gruen ME",
"Olby NJ"
] | Simon KE, Panek WK, Fefer G, Mondino A, Yang CC, Rafatpanah Baigi S, Khan MZ, Case BC, Griffith E, Gruen ME, Olby NJ. | Journal of Alzheimer's disease : JAD | 2,026 | 2026-09-29T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Alzheimer's disease",
"Cognitive Decline",
"Cognitive Aging",
"Canine Cognitive Dysfunction Syndrome",
"Canine Aging",
"Longitudinal Cognitive Decline"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1177/13872877261487575"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42806282 | 42806282 | MED | 42806282 | PMC13619339 | 10.1093/jvimsj/aalag208 | The relationship between urinalysis abnormalities, soiling behavior, and cognitive decline in aging dogs. | <h4>Background</h4>In elderly people, dementia and urinary tract dysfunction often exacerbate one another. Aging dogs also suffer cognitive decline but the relationship between cognitive decline, soiling behaviors, and urinalysis abnormalities has not been explored.<h4>Hypothesis/objectives</h4>Soiling behavior is asso... | [
"Rafatpanah Baigi S",
"Yang CC",
"Mondino A",
"Fefer G",
"Panek WK",
"Case BC",
"Griffith EH",
"Gruen ME",
"Olby NJ"
] | Rafatpanah Baigi S, Yang CC, Mondino A, Fefer G, Panek WK, Case BC, Griffith EH, Gruen ME, Olby NJ. | Journal of veterinary internal medicine | 2,026 | 2026-09-01T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dog Diseases",
"major": true,
"qualifiers": [
"psychology",
"urine"
]
},
{
"descriptor": "Urinalysis",
"... | [
"Cognitive impairment",
"Executive Function",
"Canine Cognitive Dysfunction Syndrome",
"Canine Gerontology",
"Soiling Behavior"
] | [] | true | true | true | true | cc by-nc | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1093/jvimsj/aalag208"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13619339"
},
{
"site": "Europe_PMC",
"availability": "OA"... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42798654 | 42798654 | MED | 42798654 | PMC13612547 | 10.3389/fvets.2026.1776920 | A neurotrophic withdrawal hypothesis for multisystem adverse events associated with anti-NGF therapy for canine osteoarthritis pain. | Post-marketing reports in dogs treated with <i>bedinvetmab</i> (Librela™, Zoetis), the first anti-nerve growth factor (NGF) monoclonal antibody approved for canine osteoarthritis pain, include musculoskeletal, autonomic, and neurological events. Existing interpretations address these domains separately or focus on the ... | [
"Federico G",
"Ilardi A",
"Elia V",
"Chieffi S"
] | Federico G, Ilardi A, Elia V, Chieffi S. | Frontiers in veterinary science | 2,026 | 2026-09-11T00:00:00 | [
"brief-report",
"Journal Article"
] | eng | [] | [
"Monoclonal antibodies",
"NGF",
"Adverse Events",
"Bedinvetmab",
"Librela",
"Izenivetmab",
"Lenivia"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3389/fvets.2026.1776920"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13612547"
},
{
"site": "Europe_PMC",
"availability": "... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42798481 | 42798481 | MED | 42798481 | PMC13612525 | 10.3389/fpubh.2026.1916258 | Temporal changes in allergen-specific IgE sensitization patterns in Xiamen, 2019-2023: a retrospective cross-sectional analysis. | <h4>Background</h4>The COVID-19 pandemic has induced substantial changes in environment, lifestyle, and health behaviors. We observed temporal associations between the pandemic period and declining sIgE positivity rates; however, causality cannot be established due to the retrospective observational design. Distinguish... | [
"Qu L",
"Li X",
"Wang R",
"Zhang K",
"Geng J",
"Su M",
"Lian L",
"Yang C",
"Wang H",
"Jing X"
] | Qu L, Li X, Wang R, Zhang K, Geng J, Su M, Lian L, Yang C, Wang H, Jing X. | Frontiers in public health | 2,026 | 2026-09-11T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Humans",
"major": false,
"qualifiers": []
},
{
"descriptor": "Hypersensitivity",
"major": true,
"qualifiers": [
"immunology",
"epidemiology"
]
},
{
"descriptor": "Food ... | [
"Allergy",
"Xiamen",
"Immunoglobulin E",
"Epidemiological characteristics",
"allergen",
"Retrospective Analysis",
"Covid-19 Pandemic"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3389/fpubh.2026.1916258"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13612525"
},
{
"site": "Europe_PMC",
"availability": "... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42797917 | 42797917 | MED | 42797917 | PMC13611981 | 10.3390/vetsci13090881 | Serum Cystatin C and the Urinary NAG Index Identify an Altered Renal Biochemical Phenotype in Clinically Healthy Geriatric Dogs with Normal Serum Creatinine: A Three-Tier Cross-Sectional Study. | Serum creatinine (sCr), blood urea nitrogen (BUN) and symmetric dimethylarginine (SDMA) reflect glomerular filtration only and are subject to non-renal confounders including lean body mass, limiting early detection of renal dysfunction in geriatric dogs. We evaluated serum cystatin C (sCysC) and the urinary N-acetyl-β-... | [
"Codea AR",
"Biriș A",
"Neagu D",
"Haşaş AD",
"Popovici C",
"Ursache AL",
"Popa R",
"Mircean M"
] | Codea AR, Biriș A, Neagu D, Haşaş AD, Popovici C, Ursache AL, Popa R, Mircean M. | Veterinary sciences | 2,026 | 2026-08-28T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Prevalence",
"Cystatin C",
"Tubular Injury",
"N-acetyl-β-d-glucosaminidase",
"Renal Biomarkers",
"Geriatric Dogs",
"Subclinical Kidney Disease"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/vetsci13090881"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13611981"
},
{
"site": "Europe_PMC",
"availability": "OA",... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42784859 | 42784859 | MED | 42784859 | null | 10.1016/j.cortex.2026.09.006 | Beyond dual hubs: Task and aging shape taxonomic and thematic semantic relationships in the human brain. | Semantic knowledge about concepts and their relationships is central to human cognition. Taxonomic relationships link concepts belonging to the same category (e.g. dog and bear), while thematic relationships connect concepts co-occurring in the same events (e.g. dog and leash). The dual-hub theory proposes that taxonom... | [
"Kuhnke P",
"Martin S",
"Chapman CA",
"Hartwigsen G"
] | Kuhnke P, Martin S, Chapman CA, Hartwigsen G. | Cortex; a journal devoted to the study of the nervous system and behavior | 2,026 | 2026-09-10T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Aging",
"Concepts",
"Dedifferentiation",
"fMRI",
"Semantic Memory"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.cortex.2026.09.006"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42778365 | 42778365 | MED | 42778365 | null | 10.1292/jvms.26-0252 | Computational prescreening of anticancer drugs prior to in vitro validation, primarily in dogs with exploratory cat data, based on cross-species binding conservation. | Advances in veterinary medicine have prolonged the lifespan of companion animals. As a result, the burden of neoplastic diseases has increased. While targeted anticancer drugs are widely used in human oncology, their clinical translation to companion animals remains limited. Therefore, a systematic framework for priori... | [
"Lee SW",
"Kim HY",
"Choi SK",
"Lim SG",
"Ko J",
"Park J",
"Baek SM",
"Park JK",
"Jang S",
"Kim C",
"Park S",
"Han JE",
"Kim W",
"Han S",
"Kim S"
] | Lee SW, Kim HY, Choi SK, Lim SG, Ko J, Park J, Baek SM, Park JK, Jang S, Kim C, Park S, Han JE, Kim W, Han S, Kim S. | The Journal of veterinary medical science | 2,026 | 2026-09-22T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Drug Repositioning",
"Comparative Oncology",
"Docking Simulation",
"Veterinary Oncology",
"Cross-species Docking Score"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1292/jvms.26-0252"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42774025 | 42774025 | MED | 42774025 | PMC13593421 | 10.3389/fimmu.2026.1906638 | Multiomic profiling of canine immune and metabolic aging in a cohort of young and senior beagles. | <h4>Introduction</h4>Developing a comprehensive understanding of canine aging requires integration of immune, metabolic, and genetic changes across molecular layers. While high-throughput omics have been widely applied to human aging, canine studies have typically used single modalities or small cohorts, limiting syste... | [
"Abood A",
"Louyakis AS",
"Jackson M",
"Eichman R",
"Hollar R",
"Panickar KS",
"Brockman J"
] | Abood A, Louyakis AS, Jackson M, Eichman R, Hollar R, Panickar KS, Brockman J. | Frontiers in immunology | 2,026 | 2026-09-08T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [
{
"descriptor": "Leukocytes, Mononuclear",
"major": false,
"qualifiers": [
"immunology",
"metabolism"
]
},
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "G... | [
"Gwas",
"Untargeted Metabolomics",
"Single-cell Rnaseq",
"Bulk Rnaseq",
"Canine Aging"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3389/fimmu.2026.1906638"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13593421"
},
{
"site": "Europe_PMC",
"availability": "... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42766958 | 42766958 | MED | 42766958 | null | 10.1016/j.prevetmed.2026.107021 | Multimorbidity, behaviour and QoL in ageing dogs. | Older dogs frequently develop multiple chronic conditions, accompanied by behavioural and functional changes that may adversely affect their quality of life (QoL). However, the relative contributions of multimorbidity, behavioural manifestations, and functional performance to owner-perceived QoL remain incompletely und... | [
"Kottferová J",
"Vajányi D",
"Kottferová L",
"Florian M",
"Mezníková S",
"Skurková L"
] | Kottferová J, Vajányi D, Kottferová L, Florian M, Mezníková S, Skurková L. | Preventive veterinary medicine | 2,026 | 2026-09-18T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Quality of life",
"Functional Performance",
"Multimorbidity",
"Ageing Dogs",
"Behavioural Manifestations"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.prevetmed.2026.107021"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42762824 | 42762824 | MED | 42762824 | null | 10.2460/javma.26.06.0467 | Eight-week postoperative tibial plateau leveling osteotomy radiographs do not change the prescribed management plan for most dogs. | <h4>Objective</h4>To determine how frequently routine 8-week tibial plateau leveling osteotomy (TPLO) radiographs resulted in a change to the prescribed postoperative management plan when evaluated by surgery residents versus senior clinicians, and how often the resident and senior clinician plans differed.<h4>Methods<... | [
"Hancock CL",
"Frederick SW",
"Israel SK"
] | Hancock CL, Frederick SW, Israel SK. | Journal of the American Veterinary Medical Association | 2,026 | 2026-09-18T00:00:00 | [
"Journal Article"
] | eng | [] | [
"experience",
"Alara",
"Tplo",
"Training Level",
"Routine Radiographs"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.2460/javma.26.06.0467"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42760573 | 42760573 | MED | 42760573 | PMC13587325 | 10.1186/s40575-026-00158-1 | Pedigree structure, inbreeding, and survival analysis in an Irish Wolfhound cohort. | <h4>Background</h4>The Irish Wolfhound (IW) is a giant dog breed characterized by a relatively short lifespan, a high prevalence of heritable disorders, and extensive relatedness among lineages. Despite the recognized importance of inbreeding and population structure in purebred dogs, relatively little is known about h... | [
"Ferrari C",
"Bernini F",
"Marelli SP",
"Poli M",
"Strillacci MG"
] | Ferrari C, Bernini F, Marelli SP, Poli M, Strillacci MG. | Companion animal health and genetics | 2,026 | 2026-09-18T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Survival",
"Pedigree",
"Inbreeding",
"Irish Wolfhound Dogs"
] | [] | true | true | true | true | cc by-nc-nd | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1186/s40575-026-00158-1"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13587325"
},
{
"site": "Europe_PMC",
"availability": "... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42753031 | 42753031 | MED | 42753031 | null | 10.1007/s11357-026-02533-z | Integration of methylome and transcriptome reveals age-associated signatures of stage-specific dynamics and regulatory remodeling in dogs. | Aging in mammals is characterized by widespread yet coordinated epigenetic alterations. However, integrative analyses of DNA methylation and gene expression in dogs remain largely unexplored, particularly within genetically homogeneous single-breed populations. To elucidate the molecular signatures of canine aging, we ... | [
"Kang D",
"Bok EY",
"Hong CY",
"Plassais J",
"Choe YH",
"Lee SL",
"Kim J"
] | Kang D, Bok EY, Hong CY, Plassais J, Choe YH, Lee SL, Kim J. | GeroScience | 2,026 | 2026-09-17T00:00:00 | [
"Journal Article"
] | eng | [] | [
"DNA methylation",
"Beagle Dog",
"Transcriptome",
"Epigenetic Aging",
"Stage-specific Dynamics"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1007/s11357-026-02533-z"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42751990 | 42751990 | MED | 42751990 | null | 10.1111/jsap.70198 | Age-dependent expression and heritability of owner-reported dermatological symptoms in Labrador retrievers: Implications for breeding strategies. | <h4>Objectives</h4>In decentralised breeding programmes, consistent health monitoring can be challenging, yet accurate phenotyping is essential for informed selection. This study evaluated whether a concise owner-based online survey could capture clinically relevant dermatologic signs in a Belgian assistance-dog breedi... | [
"Deboutte B",
"Lambrecht L",
"Broeckx BJG"
] | Deboutte B, Lambrecht L, Broeckx BJG. | The Journal of small animal practice | 2,026 | 2026-09-17T00:00:00 | [
"Journal Article"
] | eng | [] | [] | [
{
"grant_id": null,
"agency": "Fund Albert & Oscar",
"acronym": null
},
{
"grant_id": null,
"agency": "Assistance Dogs Purpose Dogs",
"acronym": null
}
] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1111/jsap.70198"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42749338 | 42749338 | MED | 42749338 | PMC13581454 | 10.1002/vms3.71213 | Multiple Modelling Methods Suggest That Grain-Free Diets Are Not Predictive of New Owner-Reported Cardiac Diagnoses Over Two Years in the Dog Aging Project, Despite Owner Misclassification of Diet. | <h4>Background</h4>Grain-free diets have been potentially linked to dilated cardiomyopathy (DCM) in several studies in dogs, although the underlying mechanisms for this potential link, if present, are unclear. Additionally, some studies have found no association between grain-free diets and DCM in dogs. Unfortunately, ... | [
"O'Brien J",
"Bishop M",
"",
"Tolbert MK",
"Ruple A"
] | O'Brien J, Bishop M, Dog Aging Project Consortium, Tolbert MK, Ruple A. | Veterinary medicine and science | 2,026 | 2026-09-01T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Heart Diseases",
"major": true,
"qualifiers": [
"etiology",
"epidemiology",
"veterinary"
]
},
{
"descr... | [
"Diet",
"Dogs",
"Cardiac",
"Grain‐free"
] | [
{
"grant_id": "AG057377",
"agency": "U19",
"acronym": null
},
{
"grant_id": null,
"agency": "Glenn Foundation for Medical Research",
"acronym": null
},
{
"grant_id": "U19 AG057377",
"agency": "NIA NIH HHS",
"acronym": "AG"
},
{
"grant_id": null,
"agency": "NIH... | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1002/vms3.71213"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13581454"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42748828 | 42748828 | MED | 42748828 | null | 10.1016/j.biopha.2026.119934 | Non-clinical safety evaluation of coenzyme I (NAD⁺): A GLP-compliant systematic study. | Nicotinamide adenine dinucleotide (NAD⁺) is a core coenzyme in cellular energy metabolism and redox homeostasis, with pharmacological effects in cardiovascular and neurodegenerative diseases and in aging. Its non-clinical safety was evaluated through GLP-compliant studies that included safety pharmacology (single intra... | [
"Gu J",
"Xu J",
"Yang S",
"Qiu Y",
"Yin L",
"Xu N"
] | Gu J, Xu J, Yang S, Qiu Y, Yin L, Xu N. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie | 2,026 | 2026-09-16T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Method Validation",
"Repeated Dose Toxicity",
"Safety Pharmacology",
"Nad⁺",
"Non-clinical Safety Evaluation",
"Coenzyme I"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.biopha.2026.119934"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42743987 | 42743987 | MED | 42743987 | null | 10.2460/ajvr.26.03.0102 | Cardiac pacemakers in dogs: programming parameters. | <h4>Objective</h4>To report the behavior of the main parameters used in the evaluation of cardiac pacemakers (PMs) in dogs, associated complications, and survival times.<h4>Methods</h4>This retrospective cohort study evaluated dogs that received PMs (from 2016 through 2023) at a veterinary teaching hospital. Dogs of va... | [
"Oyafuso MK",
"Triches Dornbusch P",
"Moreno JCD",
"Hamamura C",
"Sousa MG"
] | Oyafuso MK, Triches Dornbusch P, Moreno JCD, Hamamura C, Sousa MG. | American journal of veterinary research | 2,026 | 2026-09-15T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Impedance",
"Bradyarrhythmia",
"Artificial Cardiac Pacing",
"Cardiac Stimulation Parameters",
"Pacing Threshold Amplitude"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.2460/ajvr.26.03.0102"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42742206 | 42742206 | MED | 42742206 | null | 10.1128/mbio.01951-26 | The canine gut microbiome as a translational model for human health and aging. | The domestic dog is increasingly recognized as a complementary translational model for microbiome research relevant to human health while also offering direct benefits for veterinary medicine. Dogs share environments and dietary exposures with humans and show substantial taxonomic and gene-content similarity to the hum... | [
"Boldogkői Z",
"Tombácz D"
] | Boldogkői Z, Tombácz D. | mBio | 2,026 | 2026-09-15T00:00:00 | [
"Review",
"Journal Article"
] | eng | [] | [
"Dysbiosis",
"Cognitive Decline",
"One Health",
"Translational Model",
"Comparative Metagenomics",
"Long-read Sequencing",
"Canine Gut Microbiome",
"Functional Microbiomics"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1128/mbio.01951-26"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42738524 | 42738524 | MED | 42738524 | PMC13565028 | 10.3390/ani16172737 | Concurrent Multidomain Cognitive Assessment and Serum BDNF Level in Aged Dogs: Comparison Between Normal Cognition and Mild Cognitive Impairment. | Early detection of canine cognitive dysfunction syndrome (CDS) is challenged by the limitations of single diagnostic tools, including owner-reported subjectivity and impractical behavioral testing protocols. This study examined a multidomain strategy integrating questionnaires, behavioral testing, and a circulating bio... | [
"Tanongpitchayes K",
"Chuasakhonwilai A",
"Warrit K",
"Chaisri W",
"Warin R",
"Pipanmekaporn T",
"Suriyasathaporn W",
"Suriyasathaporn W"
] | Tanongpitchayes K, Chuasakhonwilai A, Warrit K, Chaisri W, Warin R, Pipanmekaporn T, Suriyasathaporn W, Suriyasathaporn W. | Animals : an open access journal from MDPI | 2,026 | 2026-09-02T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Biomarker",
"Short-term Memory",
"Novel Object Recognition",
"Canine Cognitive Dysfunction",
"Cades",
"Cognitive–Behavioral Test"
] | [
{
"grant_id": null,
"agency": "Chiang Mai University",
"acronym": null
}
] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/ani16172737"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13565028"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42738448 | 42738448 | MED | 42738448 | PMC13564329 | 10.3390/ani16172659 | Investigation of Serum Neurofilament Light Chain as a Surrogate for Cerebrospinal Fluid Neurofilament Light Chain in Canine Cognitive Dysfunction Syndrome. | The serum neurofilament light chain (NfL) is a promising circulating biomarker for canine cognitive dysfunction syndrome (CCDS). This cross-sectional study evaluated serum NfL (sNfL) as a surrogate for cerebrospinal fluid NfL (cNfL) and assessed the effects of physiological factors on its clinical utility. Biofluid NfL... | [
"Wu CC",
"Huang WH",
"Chang YP"
] | Wu CC, Huang WH, Chang YP. | Animals : an open access journal from MDPI | 2,026 | 2026-08-25T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Biomarker",
"Neurodegeneration",
"Dementia",
"Senior Care"
] | [
{
"grant_id": "NSTC 114-2313-B-002-050",
"agency": "National Science and Technology Council",
"acronym": null
},
{
"grant_id": "NTU-CC-111L892303",
"agency": "National Taiwan University",
"acronym": null
},
{
"grant_id": "NSTC 112-2635-B-002-005",
"agency": "National Science ... | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/ani16172659"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13564329"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42733759 | 42733759 | MED | 42733759 | PMC13571938 | 10.1016/j.lansea.2026.100854 | Pre-exposure prophylaxis as a complementary vaccination strategy to reduce rabies in Kerala, India: a cost-effectiveness modelling study. | <h4>Background</h4>Post-exposure prophylaxis (PEP) and dog vaccination continue to be the widely adopted vaccination strategy for rabies control in high-burden countries like India. To determine the public health and economic impacts of childhood pre-exposure prophylaxis (PrEP) relative to existing strategies, we carri... | [
"Luka MM",
"Nujum ZT",
"Asaria M",
"Ferguson EA",
"Harikumar S",
"Haydon DT",
"John RR",
"Hampson K"
] | Luka MM, Nujum ZT, Asaria M, Ferguson EA, Harikumar S, Haydon DT, John RR, Hampson K. | The Lancet regional health. Southeast Asia | 2,026 | 2026-09-05T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Elimination",
"Decision tree",
"Lyssavirus",
"One Health",
"Neglected Tropical Diseases"
] | [
{
"grant_id": "224520/Z/21/Z",
"agency": "Wellcome Trust",
"acronym": null
},
{
"grant_id": null,
"agency": "Wellcome Trust",
"acronym": "WT_"
},
{
"grant_id": "218518/Z/19/Z",
"agency": "Wellcome Trust",
"acronym": null
}
] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.lansea.2026.100854"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13571938"
},
{
"site": "Europe_PMC",
"availability":... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42728580 | 42728580 | MED | 42728580 | null | 10.1177/1098612x261491120 | EXPRESS: What Goes in the Bowl? Evidence-Based Nutrition for Ageing Domestic Cats. | With the increasing life expectancy of domestic cats, there is a growing imperative to understand and address the unique nutritional needs of senior felines. This review critically examines current knowledge regarding the physiological changes associated with feline ageing, the nutritional requirements of older cats, a... | [
"Bermingham E",
"Hoummady S",
"Schoeman T",
"Chandler M",
"Dowgray NJ"
] | Bermingham E, Hoummady S, Schoeman T, Chandler M, Dowgray NJ. | Journal of feline medicine and surgery | 2,026 | 2026-09-11T00:00:00 | [
"Review",
"Journal Article"
] | eng | [] | [
"Ageing",
"Diet",
"Nutrition",
"Sarcopenia"
] | [] | false | false | false | false | cc by-nc | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1177/1098612X261491120"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42721562 | 42721562 | MED | 42721562 | null | 10.1016/j.vetpar.2026.110922 | A nationwide epidemiological update on respiratory and intestinal nematodes in at-risk dogs in Italy. | This study updates current information on the occurrence of Capillaria aerophila, Capillaria boehmi and Angiostrongylus vasorum infections in dogs from Italy, along with the evaluation of the occurrence of intestinal parasites. Fecal samples collected from a total of 2000 dogs living in the majority of the Italian regi... | [
"Morelli S",
"Diaferia M",
"Veronesi F",
"Damiani D",
"Frangipane di Regalbono A",
"Ferroglio E",
"Humak F",
"Kramer LH",
"Allievi C",
"Barlaam A",
"Bruno G",
"Di Cesare A",
"Paoletti B",
"Murru S",
"Pede A",
"Beugnet F",
"Traversa D"
] | Morelli S, Diaferia M, Veronesi F, Damiani D, Frangipane di Regalbono A, Ferroglio E, Humak F, Kramer LH, Allievi C, Barlaam A, Bruno G, Di Cesare A, Paoletti B, Murru S, Pede A, Beugnet F, Traversa D. | Veterinary parasitology | 2,026 | 2026-09-09T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Dogs",
"epidemiology",
"Italy",
"Intestinal Helminths",
"Angiostrongylosis",
"Pulmonary Capillariosis",
"Nasal Capillariosis"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.vetpar.2026.110922"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42718794 | 42718794 | MED | 42718794 | PMC13553473 | 10.3389/fvets.2026.1898326 | Image based three-dimensional kinematic mapping to optimize femoral tunnel placement for intra-articular cranial cruciate ligament reconstruction in dogs. | <h4>Objective</h4>The development of synthetic ligaments (SLs) has sparked renewed interest in intra-articular cranial cruciate ligament (CrCL) reconstruction. In this procedure, minimizing changes in graft length through optimal tunnel placement is essential for long-term function. However, three-dimensional (3D) asse... | [
"Robine-Decourcelle C",
"Rohan PY",
"Muth-Seng C",
"Persohn S",
"Manassero M",
"Viateau V"
] | Robine-Decourcelle C, Rohan PY, Muth-Seng C, Persohn S, Manassero M, Viateau V. | Frontiers in veterinary science | 2,026 | 2026-08-26T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Surgical Planning",
"Isometry",
"Cranial Cruciate Ligament Rupture",
"Synthetic Ligament",
"3D Kinematic",
"Canine Stifle Joint"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3389/fvets.2026.1898326"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13553473"
},
{
"site": "Europe_PMC",
"availability": "... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42713254 | 42713254 | MED | 42713254 | PMC13552685 | 10.12788/fp.0671 | Whole Health(y) Aging With Gerofit: The Development of a Pilot Wellness Program for Older Veterans. | <h4>Background</h4>The Veterans Health Administration (VHA) serves > 9 million veterans, half of whom are aged ≥ 65 years. Veterans are at higher risk for comorbidities, including obesity and related chronic diseases, which contribute to increased health care costs, mobility disability, poor quality of life, and mortal... | [
"Giffuni J",
"Beans J",
"Ortmeyer H",
"Hall KS",
"Fique MT",
"Addison O",
"Dennis EA"
] | Giffuni J, Beans J, Ortmeyer H, Hall KS, Fique MT, Addison O, Dennis EA. | Federal practitioner : for the health care professionals of the VA, DoD, and PHS | 2,026 | 2026-02-20T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [] | [
{
"grant_id": "P30 AG028716",
"agency": "NIA NIH HHS",
"acronym": "AG"
},
{
"grant_id": "I01 RX003120",
"agency": "RRD VA",
"acronym": "RX"
}
] | false | true | true | true | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.12788/fp.0671"
},
{
"site": "Europe_PMC",
"availability": "F",
"style": "html",
"url": "https://europepmc.org/articles/PMC13552685"
},
{
"site": "Europe_PMC",
"availability": "F",
"st... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42706237 | 42706237 | MED | 42706237 | PMC13550594 | 10.1038/s41413-026-00581-x | Single-cell multi-omics defines H3K27me3 remodelling in intervertebral disc degeneration with implications for regenerative intervention. | Utilizing key developmental cues and refining their orchestrating role in degeneration represents a promising strategy for understanding and treating intervertebral disc (IVD) degeneration, a major cause of chronic lower back pain. Here, we focus on notochordal cells (NCs), which originate from the embryonic notochord ... | [
"Poramba-Liyanage DW",
"Tong X",
"Riemers FM",
"Meij BP",
"Dilek Y",
"Cleypool CGJ",
"Kamali SA",
"Le Maitre CL",
"Camus A",
"Chan D",
"van Oudenaarden A",
"Zeller P",
"Tryfonidou MA"
] | Poramba-Liyanage DW, Tong X, Riemers FM, Meij BP, Dilek Y, Cleypool CGJ, Kamali SA, Le Maitre CL, Camus A, Chan D, van Oudenaarden A, Zeller P, Tryfonidou MA. | Bone research | 2,026 | 2026-09-07T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [
{
"descriptor": "Notochord",
"major": false,
"qualifiers": [
"metabolism"
]
},
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Humans",
"major": false,
"q... | [] | [
{
"grant_id": "825925",
"agency": "EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020)",
"acronym": null
},
{
"grant_id": "174991",
"agency": "Swiss National Science Foundation",
"acronym": null
},
{
"grant_id": "LT000209/2018-L",
... | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1038/s41413-026-00581-x"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13550594"
},
{
"site": "Europe_PMC",
"availability": "... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42692161 | 42692161 | MED | 42692161 | null | 10.1016/j.bbabio.2026.149605 | Effects of increases in temperature and genipin on mitochondrial function in primary fibroblast cells of dogs of different sizes and ages. | In homeotherms, heat loss and the need for heat production are increased in small animals compared with large ones, and mitochondria are the primary organelles responsible for heat production in animals. Because of this, in animals of different body sizes, mitochondria may differ in their sensitivity to temperature and... | [
"Jiménez AG",
"Warriner M",
"Molyneux D",
"Cipolli W",
"Champagne AM"
] | Jiménez AG, Warriner M, Molyneux D, Cipolli W, Champagne AM. | Biochimica et biophysica acta. Bioenergetics | 2,026 | 2026-09-03T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Ucp2",
"Primary Fibroblasts",
"Domestic Dogs",
"Mitochondrial Heat Sensitivity"
] | [
{
"grant_id": null,
"agency": "National Science Foundation",
"acronym": null
}
] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.bbabio.2026.149605"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42689384 | 42689384 | MED | 42689384 | PMC13539535 | 10.1002/vms3.71187 | Severe Hypernatraemia Secondary to Adipsia Associated With a Pituitary Macroadenoma in a Dog: A Case Report. | <h4>Background</h4>Adipsia is a rare disorder characterised by absence of thirst despite hyperosmolality, resulting from dysfunction of the hypothalamic thirst centre. In veterinary medicine, most reported cases of adipsia are associated with congenital forebrain abnormalities, whereas acquired causes in adult dogs are... | [
"Choo GB",
"Choi BK",
"Choi S",
"Noh D",
"An JH"
] | Choo GB, Choi BK, Choi S, Noh D, An JH. | Veterinary medicine and science | 2,026 | 2026-09-01T00:00:00 | [
"case-study",
"Journal Article",
"Case Reports"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Adenoma",
"major": true,
"qualifiers": [
"complications",
"diagnosis",
"veterinary"
]
},
{
"descriptor... | [
"Electrolyte Imbalance",
"Hypothalamic Dysfunction",
"Intracranial Neoplasia",
"Water Balance Disorder",
"Pituitary‐dependent Hyperadrenocorticism"
] | [
{
"grant_id": null,
"agency": "the National Research Foundation of Korea (NRF) grant funded by the Korea Government (MSIT)",
"acronym": null
}
] | true | true | true | true | cc by-nc-nd | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1002/vms3.71187"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13539535"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42688807 | 42688807 | MED | 42688807 | PMC13535678 | 10.30476/dentjods.2025.107027.2711 | <i>In vitro</i> Evaluation of the Remineralizing Potential and Color Change of Modified Fluoride Varnish with Polyvinylpyrrolidone-Coated Silver Nanoparticles on Incipient Enamel Lesions in Primary Teeth. | <h4>Background</h4>Dental caries is closely associated with biofilms and characterized by cycles of demineralization and remineralization that weaken tooth structure over time. Given the need for effective prevention and enhanced remineralization, developing a more esthetic and efficient approach is essential in improv... | [
"Farahmand F",
"Rafiee A",
"Mohammadi N"
] | Farahmand F, Rafiee A, Mohammadi N. | Journal of dentistry (Shiraz, Iran) | 2,026 | 2026-09-01T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Fluorides",
"Microscopy",
"Nanoparticles",
"Tooth Remineralization",
"Silver Compounds"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.30476/dentjods.2025.107027.2711"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13535678"
},
{
"site": "Europe_PMC",
"availabi... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42687149 | 42687149 | MED | 42687149 | PMC13540077 | 10.1186/s12877-026-08157-4 | A mixed-methods feasibility study of dog-assisted exercise therapy in geriatric inpatients. | <h4>Background</h4>Animal-assisted therapy (AAT) is a promising complementary approach in geriatric rehabilitation, but evidence on feasibility and patient experiences remains limited.<h4>Methods</h4>This exploratory, mixed-methods, two-arm randomized controlled parallel-group design (RCT) compared dog-assisted exercis... | [
"Joschko L",
"Jansen E",
"Weinert S",
"Hinse M",
"Zerm R",
"Matthes H"
] | Joschko L, Jansen E, Weinert S, Hinse M, Zerm R, Matthes H. | BMC geriatrics | 2,026 | 2026-08-29T00:00:00 | [
"research-article",
"Randomized Controlled Trial",
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Humans",
"major": false,
"qualifiers": []
},
{
"descriptor": "Exercise Therapy",
"major": true,
"qualifiers": [
... | [
"Mobility",
"Depression",
"Motivation",
"Satisfaction",
"Rct",
"Aat"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1186/s12877-026-08157-4"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13540077"
},
{
"site": "Europe_PMC",
"availability": "... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42670516 | 42670516 | MED | 42670516 | PMC13526283 | 10.1155/vmi/7159552 | Circulating pTau181 and Genomic Background in Dogs: A Pilot Study on Neurobiological Aging. | Aging in dogs mirrors key biological aspects of human aging, including molecular processes associated with neurodegeneration, making the dog a valuable comparative model. This pilot study investigated the integration of circulating blood biomarkers and genomic architecture to explore interindividual variability associa... | [
"Gazzano V",
"Fabbri MC",
"Capsoni S",
"Cantile C",
"Tinacci L",
"Gazzano A",
"Curadi MC",
"Cecchi F"
] | Gazzano V, Fabbri MC, Capsoni S, Cantile C, Tinacci L, Gazzano A, Curadi MC, Cecchi F. | Veterinary medicine international | 2,026 | 2026-08-30T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Gwas",
"Phosphorylated Tau",
"Labrador Retriever",
"Genomic Inbreeding",
"Dog Aging"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1155/vmi/7159552"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13526283"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42655823 | 42655823 | MED | 42655823 | PMC13517202 | 10.3390/vetsci13080803 | qEEG and Functional Connectivity as a Translational Bridge Between Humans and Dogs in Epilepsy and Associated Disorders: From Spontaneous Model to Automatic Classification-An Integrative Review. | Quantitative electroencephalography (qEEG) converts the raw EEG signal into reproducible numerical descriptors (spectral power, hemispheric symmetry, coherence and signal complexity) and has emerged as a candidate translational biomarker linking human and canine neurology. This integrative review examined the diagnosti... | [
"Anghelinici D",
"Musteata M"
] | Anghelinici D, Musteata M. | Veterinary sciences | 2,026 | 2026-08-14T00:00:00 | [
"review-article",
"Review",
"Journal Article"
] | eng | [] | [
"Dog",
"Functional Connectivity",
"Quantitative Eeg",
"Qeeg",
"Eeg Coherence",
"Integrative Review",
"Translational Model",
"Canine Cognitive Dysfunction",
"Canine Epilepsy"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/vetsci13080803"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13517202"
},
{
"site": "Europe_PMC",
"availability": "OA",... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42655785 | 42655785 | MED | 42655785 | PMC13517765 | 10.3390/vetsci13080765 | Eicosapentaenoic Acid (EPA) Alleviates Oxidative Stress and Inflammatory Responses in Canine Ileal Epithelial Cells. | Fueled by the rapid growth of the global companion animal industry, the development of nutritional additives for improving canine intestinal health has emerged as a prominent research area in pet nutrition. Excessive reactive oxygen species accumulation triggers severe oxidative stress, inducing intestinal inflammation... | [
"Yuan X",
"Zhu X",
"Zhu C",
"Wang Y",
"Li C",
"Yu M",
"Meng F",
"Hu P",
"Liu H",
"Chen Q",
"Cai D"
] | Yuan X, Zhu X, Zhu C, Wang Y, Li C, Yu M, Meng F, Hu P, Liu H, Chen Q, Cai D. | Veterinary sciences | 2,026 | 2026-07-31T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Oxidative stress",
"Eicosapentaenoic acid",
"Cellular senescence",
"Intestinal barrier",
"Canine Ileal Epithelial Cells"
] | [
{
"grant_id": "KYCX25_4057",
"agency": "Postgraduate Research & Practice Innovation Program of Jiangsu Province",
"acronym": null
}
] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/vetsci13080765"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13517765"
},
{
"site": "Europe_PMC",
"availability": "OA",... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42651919 | 42651919 | MED | 42651919 | PMC13508923 | 10.3390/ani16162515 | Effects of Complementary Feed with Postbiotics Derived from <i>Bacillus subtilis</i> on Nutrient Digestibility, Faecal Characteristics, Gut Microbiota, Metabolic and Immune Responses, and Coat Quality in Healthy Senior Dogs. | The aim of this study was to evaluate the effects of a <i>Bacillus subtilis</i>-derived postbiotic on apparent total tract nutrient digestibility, faecal fermentation characteristics, gut microbiota, immune response, blood biochemistry, hematological parameters, serum trace minerals, and coat quality in healthy senior ... | [
"Kahraman O",
"Wilk M",
"Bochynek M",
"Bojanowski K",
"Quijas G",
"Inanc ZS",
"Inal F",
"Ahmed I",
"Lewińska A",
"Yilmaz B"
] | Kahraman O, Wilk M, Bochynek M, Bojanowski K, Quijas G, Inanc ZS, Inal F, Ahmed I, Lewińska A, Yilmaz B. | Animals : an open access journal from MDPI | 2,026 | 2026-08-12T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Bacillus subtilis",
"Digestibility",
"Blood biochemistry",
"Immunity",
"Gut Microbiota",
"Postbiotic",
"Senior Dogs"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/ani16162515"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13508923"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42645464 | 42645464 | MED | 42645464 | PMC13510857 | 10.3390/dj14080490 | Retentive Force Assessment and Wear Exploration of CAD-CAM Fabricated PEEK, Zirconia, and PMMA Mini Ball Attachments for Tooth-Supported Overdenture: A Laboratory Study. | <b>Background/Objectives</b>: The longevity of tooth-supported overdentures depends on the retentive stability of attachment systems, yet limited evidence exists on the performance of non-metallic CAD-CAM fabricated mini ball attachments. This study aimed to evaluate the retentive force changes and surface wear of CAD-... | [
"Kamel A",
"Tsoi JKH",
"Mohsen H"
] | Kamel A, Tsoi JKH, Mohsen H. | Dentistry journal | 2,026 | 2026-08-06T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"computer-aided design",
"Overlay",
"Zirconium",
"Dental Materials",
"Polymethyl Methacrylate",
"Denture",
"Dental Prosthesis Retention",
"Polyetheretherketone",
"Dental Abutments"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.3390/dj14080490"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13510857"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42629518 | 42629518 | MED | 42629518 | null | 10.1007/s11357-026-02482-7 | Human-analogue age-related dynamics of dog-human attachment. | Family dogs' human-analogue attachment to the owner has long been recognised; however, how this dog-owner attachment develops and changes with age remains an open question. We examined age-related variation and the effect of training experience on the attachment behaviour in family dogs (N = 222) using the Strange Sit... | [
"Csepregi M",
"Carreiro C",
"Świerkosz S",
"de Jong T",
"Lehoczki F",
"Miklósi Á",
"Gácsi M"
] | Csepregi M, Carreiro C, Świerkosz S, de Jong T, Lehoczki F, Miklósi Á, Gácsi M. | GeroScience | 2,026 | 2026-08-21T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Ageing",
"Attachment",
"Strange Situation Test",
"Dog–human Interaction",
"Family Dog"
] | [
{
"grant_id": "EKÖP-24-3-II-ELTE-645",
"agency": "EKÖP-24 University Excellence Scholarship Program",
"acronym": null
},
{
"grant_id": "F01/03",
"agency": "HUN-REN-ELTE Comparative Ethology Research Group",
"acronym": null
}
] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1007/s11357-026-02482-7"
}
] | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42624279 | 42624279 | MED | 42624279 | null | 10.1016/j.tvjl.2026.106841 | Lesion distribution based on oral biopsy and histopathology in dogs: A retrospective study of 338 cases (2015-2025). | The histopathologic spectrum of canine oral lesions can vary significantly by geographic region and breed demographics. This retrospective study aimed to characterize the distribution of 338 biopsy-confirmed canine oral masses in the Republic of Korea, where small-breed dogs predominate. Lesions were categorized into t... | [
"Kim CG",
"Jeong KJ",
"Kim J",
"Vapniarsky N",
"Kang SS",
"Kim SE",
"Jo HM"
] | Kim CG, Jeong KJ, Kim J, Vapniarsky N, Kang SS, Kim SE, Jo HM. | Veterinary journal (London, England : 1997) | 2,026 | 2026-08-20T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Tumor",
"Histopathology",
"Tumor-like Lesion",
"Small-breed Dog",
"Canine Oral Mass"
] | [
{
"grant_id": null,
"agency": "National Research Foundation of Korea",
"acronym": null
}
] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.tvjl.2026.106841"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42594946 | 42594946 | MED | 42594946 | null | 10.2460/ajvr.26.06.0245 | Targeted quantitative polymerase chain reaction-based bacterial and fecal metabolite markers show early stability in healthy puppies after 8 weeks of age. | <h4>Objective</h4>To assess longitudinal stability of targeted quantitative PCR (qPCR)-based fecal microbial and metabolomic markers in healthy puppies from 8 weeks to 1 year of age.<h4>Methods</h4>This prospective longitudinal cohort study was conducted at the Clinic for Small Animal Internal Medicine, Vetsuisse Facul... | [
"Birk D",
"Weidinger AK",
"Schmidt T",
"Bachmann S",
"Spring I",
"Felten S",
"Meunier SM",
"Blake AB",
"Suchodolski JS",
"Unterer S"
] | Birk D, Weidinger AK, Schmidt T, Bachmann S, Spring I, Felten S, Meunier SM, Blake AB, Suchodolski JS, Unterer S. | American journal of veterinary research | 2,026 | 2026-08-13T00:00:00 | [
"Journal Article"
] | eng | [] | [
"Bile acids",
"Metabolomic Markers",
"Puppies",
"Dysbiosis Index",
"Targeted Qpcr"
] | [] | false | false | false | false | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.2460/ajvr.26.06.0245"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42572116 | 42572116 | MED | 42572116 | PMC13454156 | 10.1111/vop.70245 | Breed-Specific Relationship Between Rebound Tonometers (TonoVet and TonoVet Plus) in Labrador Retrievers. | <h4>Objective</h4>This study aimed to characterize the relationship between intraocular pressure (IOP) measurements obtained using two rebound tonometers (TonoVet and TonoVet Plus) in Labrador retrievers and to evaluate a regression-based approximation for supporting longitudinal interpretation following device replace... | [
"Sugiura A",
"Yogo T"
] | Sugiura A, Yogo T. | Veterinary ophthalmology | 2,026 | 2026-09-01T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": [
"physiology"
]
},
{
"descriptor": "Tonometry, Ocular",
"major": true,
"qualifiers": [
"instrumentation",
"veterinary"
]
},
... | [
"intraocular pressure",
"Labrador Retriever",
"Rebound Tonometry",
"Guide Dogs",
"Tonovet",
"Tonovet Plus"
] | [] | false | true | true | true | null | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1111/vop.70245"
},
{
"site": "Europe_PMC",
"availability": "F",
"style": "html",
"url": "https://europepmc.org/articles/PMC13454156"
},
{
"site": "Europe_PMC",
"availability": "F",
"s... | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42571817 | 42571817 | MED | 42571817 | null | 10.1016/j.tvjl.2026.106817 | Sleep-wake disturbance in canine cognitive dysfunction: Guardian-reported patterns and a practical screening tool. | Sleep-wake disturbance is a commonly reported feature of canine cognitive dysfunction (CCD), yet its specific patterns and clinical significance remain poorly characterised. This study aimed to describe guardian-reported sleep disturbances in dogs with CCD, examine their associations with cognitive severity and sensory... | [
"Taylor TL",
"Tuke J",
"Hazel SJ"
] | Taylor TL, Tuke J, Hazel SJ. | Veterinary journal (London, England : 1997) | 2,026 | 2026-08-09T00:00:00 | [
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dog Diseases",
"major": true,
"qualifiers": [
"diagnosis",
"etiology",
"physiopathology"
]
},
{
"descr... | [
"Vision",
"Decision tree",
"hearing",
"Sleep-wake Cycle",
"Cognitive Dysfunction Syndrome"
] | [
{
"grant_id": null,
"agency": "The University of Adelaide",
"acronym": null
}
] | false | false | false | false | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1016/j.tvjl.2026.106817"
}
] | [
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42566137 | 42566137 | MED | 42566137 | PMC13451518 | 10.1007/s11259-026-11425-8 | Advances in biomarker discovery for canine cognitive dysfunction: a comprehensive structured narrative review and future perspectives. | Canine Cognitive Dysfunction (CCD) is a naturally occurring neurodegenerative syndrome in aging dogs that shares clinical and neuropathological parallels with Alzheimer's disease (AD). As the demand for objective diagnostic tools grows, identifying reliable biofluid biomarkers is essential for clinical staging and ther... | [
"Barbosa KA",
"Ribeiro HM",
"Benevenuto LGD",
"Maiorka PC",
"Cominetti MR",
"Amorim RM",
"Cagnini DQ"
] | Barbosa KA, Ribeiro HM, Benevenuto LGD, Maiorka PC, Cominetti MR, Amorim RM, Cagnini DQ. | Veterinary research communications | 2,026 | 2026-08-07T00:00:00 | [
"review-article",
"Review",
"Journal Article"
] | eng | [
{
"descriptor": "Animals",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dogs",
"major": false,
"qualifiers": []
},
{
"descriptor": "Dog Diseases",
"major": true,
"qualifiers": [
"blood",
"cerebrospinal fluid",
"diagnosis"
]
},
{
"desc... | [
"Dogs",
"Tau",
"Glial fibrillary acidic protein",
"Biomarkers",
"Translational Medicine",
"Amyloid-β",
"Canines",
"Canine Cognitive Dysfunction",
"Neurofilament-light Chain"
] | [
{
"grant_id": null,
"agency": "Universidade Estadual Paulista Júlio De Mesquita Filho",
"acronym": null
}
] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1007/s11259-026-11425-8"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13451518"
},
{
"site": "Europe_PMC",
"availability": "... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
MED:42564270 | 42564270 | MED | 42564270 | PMC13442920 | 10.1002/vro2.70047 | Minimally processed, human-grade diet alters canine epigenetic ageing: Results from a pilot study. | <h4>Background</h4>Diet plays a critical role in promoting wellness and longevity in both humans and canines. Epigenetic ageing clocks have emerged as accurate tools for assessing biological ageing and evaluating dietary and lifestyle interventions in humans and mice.<h4>Methods</h4>A dog-specific epigenetic ageing clo... | [
"Chen A",
"Guo W",
"Krumbeck JA",
"Su D",
"Michels V",
"Yang X"
] | Chen A, Guo W, Krumbeck JA, Su D, Michels V, Yang X. | Veterinary record open | 2,026 | 2026-08-05T00:00:00 | [
"research-article",
"Journal Article"
] | eng | [] | [
"Ageing",
"DNA methylation",
"Canine",
"Epigenetics",
"Epigenetic Age",
"Kibble Diet",
"Minimally Processed Diet"
] | [] | true | true | true | true | cc by | 0 | [
{
"site": "DOI",
"availability": "S",
"style": "doi",
"url": "https://doi.org/10.1002/vro2.70047"
},
{
"site": "Europe_PMC",
"availability": "OA",
"style": "html",
"url": "https://europepmc.org/articles/PMC13442920"
},
{
"site": "Europe_PMC",
"availability": "OA",
... | [
"core",
"extended"
] | 2026-10-01T14:18:03 | raw/europepmc/search/extended/20261001T141803+0000/page_0000.json |
End of preview. Expand in Data Studio
Canine Aging Corpus
A versioned, reproducible corpus of the canine aging and longevity literature, built from
the Europe PMC REST API by the
canine-aging-corpus pipeline. It exists so
that agents and retrieval systems can work over a fixed, citable snapshot of what has been
published about dogs as a model of aging, instead of live search results that change daily.
| Records | 3,565 works (records), of which 2,185 match the strict core query |
| Full text | Markdown for the open-access articles whose licence allows redistribution: CC BY or CC0 (fulltext, also as fulltext/md/PMC*.md) |
| Manifest | one row per record with identifiers, year, journal, licence, and which artefacts exist (manifest) |
| Snapshot | corpus_version.json: query definitions, counts by tier / source / year, SHA-256 of records.jsonl, build time (2026-09-29) |
Query tiers
Every record carries the list of tiers it matched, so consumers can filter.
- core:
(dog OR dogs OR canine OR "Canis familiaris") AND (aging OR ageing OR lifespan OR longevity OR geroscience)in title or abstract. High precision. - extended: adds geriatric, senior, age-related, healthspan, frailty, senescence, cognitive dysfunction, rapamycin, life expectancy. Higher recall, more clinical noise.
Fields (records)
key (Europe PMC source:id, e.g. MED:38263575), source, id, pmid, pmcid, doi,
title, abstract, authors, author_string, journal, year, first_publication_date,
pub_types, keywords, mesh (descriptor, major flag, qualifiers), grants,
is_open_access, license, in_pmc, in_epmc, has_pdf, fulltext_urls, cited_by_count,
language, tiers, retrieved_at, raw_page (which raw search page the record came from).
fulltext rows: pmcid, pmid, doi, title, journal, year, license, source
(which service served the JATS XML: ncbi or europepmc), article_type, chars,
markdown (front matter, title, abstract, body sections with heading levels, table and
figure captions; references dropped).
How it was built
cd corpus && uv sync
uv run cac fetch-metadata --tier core && uv run cac fetch-metadata --tier extended
uv run cac fetch-fulltext --source ncbi # batched NCBI E-utilities efetch; Europe PMC is the fallback
uv run cac convert && uv run cac manifest
JATS XML is converted deterministically (no model involved). Raw API pages are kept by the
pipeline for provenance and cac rebuild-records reconstructs records.jsonl from them.
Limitations
- Full text covers 1,140 of the 1,347 records with a PMCID locally; 207 are restricted by
their publisher from XML distribution. Only the CC BY / CC0 subset is redistributed here;
articles under CC BY-NC variants or without a licence statement are excluded from this
repository (
fulltext_manifest.jsonhas the counts) and can be fetched by the pipeline. - Europe PMC's
licensefield is only populated for part of the open-access set; records with an empty licence are treated as non-redistributable. - Query-based corpora have recall limits: some classic papers that do not use the query vocabulary in their title or abstract are absent.
Licence
Metadata and abstracts: retrieved from Europe PMC and redistributed under
Europe PMC's terms; abstract copyright stays with the
publishers and authors. Full text: each article's own licence (CC BY or CC0), stated per
row and in each Markdown file's front matter. The compilation: CC BY 4.0. See LICENSE.
Related
w0lph/canine-geroscience-questions: a grounded question set over this corpus.w0lph/dog-geroscience-mcp-data: the SQLite database that indexes this corpus for thedog-geroscience-mcpserver.- Pipeline and documentation: https://github.com/w0lph/k9/tree/main/corpus
- Downloads last month
- 168