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NCT01340469 | Nosocomial Infections and Necrotizing Enterocolitis in Preterm Neonates Treated With Lactobacillus Acidophilus and Bifidobacterium Infantis in An Intensive Care Unit : A Randomized Controlled Study | King Chulalongkorn Memorial Hospital | COMPLETED | PHASE3 | INTERVENTIONAL | null | null | Nosocomial Infection, Necrotizing Enterocolitis | probiotics | null | academic | completed | infectious_disease | infectious_disease |
NCT00132756 | Liposomal Doxorubicin and Estramustine Phosphate: A Phase II Study in Taxane Resistant, Hormone Refractory Advanced Prostate Cancer | Morton Plant Mease Health Care | TERMINATED | PHASE1, PHASE2 | INTERVENTIONAL | null | null | Prostate Cancer | Doxil and Estramustine | null | other | failed | oncology | oncology |
NCT03405415 | Assessment of Glucose Concentrations in People Without Diabetes Mellitus After Standardized Meals and in Daily Life | Institut für Diabetes-Technologie Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm | COMPLETED | NA | INTERVENTIONAL | 2018-01-27 | 2019-07-10 | Subjects Without Diabetes Mellitus, Assessment of Glucose Concentrations | Blood glucose monitoring system and continuous interstitial glucose monitoring system | 0 | other | completed | null | null |
NCT00126919 | Randomized Crossover Trial of Sonication Followed by 5 Minute LMX4 Application Compared With 30 Minute LMX4 Application for Topical Anesthesia Prior to Subcutaneous Port Access in Children | Connecticut Children's Medical Center | COMPLETED | PHASE4 | INTERVENTIONAL | null | null | Pain | SonoPrep | null | academic | completed | musculoskeletal | musculoskeletal |
NCT04788433 | ROCCO - Registry of Coronavirus Complications. Prospective Observational Study on Coronavirus Complications and Correlation With Glycomic Profile in COVID-19 Patients | Papa Giovanni XXIII Hospital | COMPLETED | OBSERVATIONAL | 2021-03-04 | 2021-09-10 | Chronic Pain, Morbidity, Multiple, Covid19 | Phone interview, glycomic analysis | 0 | academic | completed | infectious_disease | infectious_disease; musculoskeletal | |
NCT00275145 | Peripheral Effects of Exercise on Cardiovascular Health (STRRIDE II) | Duke University | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Cardiovascular Diseases, Heart Diseases, Obesity, Hyperlipidemia, Insulin Resistance, Metabolic Syndrome X | Aerobic Exercise, Combo, Continued Sedentary lifestyle, Resistance Training | null | academic | completed | cardiovascular | cardiovascular; metabolic |
NCT02828137 | Relationships Between Neutrophil-to-Lymphocyte Ratio and Index of Microcirculatory Resistance in ST-segment Elevation Myocardial Infarction Patients Undergone Primary Percutaneous Coronary Intervention | Inha University Hospital | COMPLETED | OBSERVATIONAL | null | null | Myocardial Infarction, Death | null | academic | completed | cardiovascular | cardiovascular; other | ||
NCT00015886 | Docetaxel (Taxotere) and 5-Fluorouracil As Second- Or Third-Line Chemotherapy In Women With Metastatic Breast Cancer | Wake Forest University Health Sciences | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Breast Cancer | docetaxel, fluorouracil | null | academic | completed | oncology | oncology |
NCT00118937 | Effect of Metformin On Glycaemic Control and Non-Glycaemic Cardiovascular Risk-Factors in Patients With Type-1 Diabetes, With Long-Standing Inadequate Glycaemic Control by Insulin and Diet | Steno Diabetes Center Copenhagen | COMPLETED | PHASE4 | INTERVENTIONAL | null | null | Diabetes Mellitus, Type 1 | Metformin, Placebo. | null | other | completed | metabolic | metabolic |
NCT02740777 | Immunogenicity Study of a 2-dose Immunization Schedule of Recombinant Human Papillomavirus Virus-like Particle Vaccine (Type 16 and 18 L1 Proteins, Yeast) in Adolescent Females Aged 9 to 14 Years | Shanghai Zerun Biotechnology Co.,Ltd | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Human Papillomavirus, Cervical Intraepithelial Neoplasia, Persistent Infection | HPV-16/18 vaccine | null | industry | completed | null | null |
NCT03848702 | Nonoperative Treatment of Dorsally Dislocated Distal Radius Fractures in Adults With an Individualized 3D Printed Brace; a Tolerability Study in Healthy Volunteers and Patients (DRFB) | VieCuri Medical Centre | COMPLETED | NA | INTERVENTIONAL | 2017-07-01 | 2018-06-01 | Dorsal Displacement | Distal radius fracture brace | 0 | other | completed | null | null |
NCT06595914 | Improving In-hospital and Post-discharge Patient Education for Mild Traumatic Brain Injury | Medical College of Wisconsin | ENROLLING_BY_INVITATION | NA | INTERVENTIONAL | 2024-09-11 | null | Concussion, Mild, Traumatic Brain Injury | Clinical implementation strategies | null | academic | active | neurology | neurology; other |
NCT02252809 | An Open-Label, Parallel Group, Controlled Study in Healthy Subjects to Characterize Biological Responses to Immunological Challenges and to Measure the Effect of Marketed Anti-Inflammatory Agents on Those Responses | Brugmann University Hospital | COMPLETED | EARLY_PHASE1 | INTERVENTIONAL | null | null | Innate Immunity | adalimumab, methylprednisolone | null | academic | completed | null | null |
NCT03268174 | A Placebo-Controlled, Double-Blind, Bilateral Cosmetic Study With an Open Label Extension to Evaluate the Performance of a Cosmetic Product Designed to Improve the Appearance of Skin Afflicted With Mild to Moderate Atopic Dermatitis. | AOBiome LLC | COMPLETED | NA | INTERVENTIONAL | 2016-05-11 | 2017-02-13 | Atopic Dermatitis Eczema | AO+Mist, Placebo | 0 | industry | completed | dermatology | dermatology |
NCT01993836 | Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care | Duke University | COMPLETED | PHASE4 | INTERVENTIONAL | null | 2019-01-10 | Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction | General anesthesia with isoflurane, Total intravenous anesthesia with propofol | null | academic | completed | neurology | neurology |
NCT01868828 | A Multicenter, Double Arms, Prospective Phase 4 Study to Evaluating the Efficacy and Safety of Combination Therapy of PAD Versus VCD Treatment in Previously Untreated Subjects With Multiple Myeloma. | Peking University People's Hospital | UNKNOWN | PHASE4 | INTERVENTIONAL | null | null | Multiple Myeloma | ASCT, PAD, VCD | null | academic | unknown | oncology | oncology |
NCT04514367 | A Phase 2a Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease | Annexon, Inc. | COMPLETED | PHASE2 | INTERVENTIONAL | 2020-08-17 | 2022-01-28 | Huntington Disease | ANX005 | 0 | industry | completed | neurology | neurology |
NCT07011108 | Machine Learning for Estimating Cardiorespiratory Fitness in Patients With Obesity | Sykehuset i Vestfold HF | ACTIVE_NOT_RECRUITING | OBSERVATIONAL | 2025-05-30 | 2027-12-10 | Obesity; Overweight | No intervention (observational study) | 0 | other | active | null | null | |
NCT00084435 | Adjuvant Chemo-RT With Cisplatin (NSC-119875) and Docetaxel (NSC-628503) After Complete Resection of Locally Advanced (Stage III and IV) Squamous Cell Carcinoma of the Head and Neck (SCCHN) | SWOG Cancer Research Network | WITHDRAWN | PHASE2 | INTERVENTIONAL | null | null | Head and Neck Cancer | cisplatin, docetaxel, radiation therapy | null | other | failed | oncology | oncology |
NCT05172986 | Enhanced Recovery Program After a Robotic-assisted Surgery (RAAC) of Radical Prostatectomy. PROSTA-RAAC | Elsan | COMPLETED | NA | INTERVENTIONAL | 2021-10-27 | 2023-12-31 | Prostate Cancer, Quality of Life, Recovery Programm | Follow-up patient program | 0 | other | completed | oncology | oncology; other |
NCT01119027 | Assessing Effectiveness of Laparoscopic Colorectal Surgical Skills | University Hospitals Cleveland Medical Center | TERMINATED | OBSERVATIONAL | null | null | Colonic Diseases | null | academic | failed | null | null | ||
NCT04049500 | An Observational Study to Adapt a Digital Diabetes Prevention Program (dDPP) and Incorporate it Into the Clinical Workflows. | NYU Langone Health | WITHDRAWN | OBSERVATIONAL | null | null | Physician-Patient Relations, Nurse-Patient Relations | Digital Diabetes Prevention Program (dDPP) | null | other | failed | null | null | |
NCT02561260 | Multicenter and Prospective Clinical Registry Study of Autoimmune Encephalitis in China | Beijing Tongren Hospital | UNKNOWN | OBSERVATIONAL | null | null | Autoimmune Encephlitis in China | null | academic | unknown | null | null | ||
NCT00116298 | A Study to Compare Long-Term Safety and Tolerability of Stavudine (d4T) Extended Release (ER) Versus Conventional (Immediate Release, IR) Formulations, Each In Combination With Lamivudine (3TC) and Efavirenz (EFV) in Subjects Who Have Completed BMS Studies AI455-096 and AI455-099 | Bristol-Myers Squibb | COMPLETED | PHASE3 | INTERVENTIONAL | null | null | HIV Infections, AIDS | stavudine, efavirenz, lamivudine | null | industry | completed | infectious_disease | infectious_disease |
NCT06609161 | A Study to Evaluate the Definitive Bioequivalence of Tedizolid Phosphate Single-Unit-Dose Sachet Powder for Oral Suspension Compared to Tedizolid Phosphate Powder for Oral Suspension Bottle Used in Pediatric Clinical Studies | Merck Sharp & Dohme LLC | COMPLETED | PHASE1 | INTERVENTIONAL | 2024-07-16 | 2024-08-08 | Healthy | Tedizolid Phosphate Oral Formulation 1 (Reference), Tedizolid Phosphate Oral Formulation 2 (Test) | 0 | industry | completed | healthy_volunteers | healthy_volunteers |
NCT02592434 | EFFICACY, SAFETY AND TOLERABILITY OF TOFACITINIB FOR TREATMENT OF POLYARTICULAR COURSE JUVENILE IDIOPATHIC ARTHRITIS (JIA) IN CHILDREN AND ADOLESCENT SUBJECTS | Pfizer | COMPLETED | PHASE3 | INTERVENTIONAL | 2016-06-10 | 2019-05-16 | Juvenile Idiopathic Arthritis | CP-690,550 (tofacitinib), placebo | 0 | industry | completed | musculoskeletal | musculoskeletal |
NCT03721094 | Cognitive Load and Performance in Immersive Virtual Reality Versus Conventional Virtual Reality Simulation Training of Laparoscopic Surgery - a Randomized Trial | Copenhagen Academy for Medical Education and Simulation | COMPLETED | NA | INTERVENTIONAL | 2018-02-14 | 2018-06-05 | Cognitive Load, Performance | Immersive virtual reality | 0 | other | completed | null | null |
NCT03472118 | Apneic Oxygenation Using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) in Adult Patients Undergoing Suspension Laryngoscopy Under General Anesthesia: a Multicenter Study | CMC Ambroise Paré | TERMINATED | NA | INTERVENTIONAL | 2018-07-05 | 2019-01-24 | Laryngoscopy, Apnea, Anesthesia | Nasal High Flow Oxygen | 0 | other | failed | null | other |
NCT00534365 | A Randomized Trial Comparing Tension-free Vaginal Tape (TVT) to the TVT-SECUR for the Surgical Treatment of Stress Urinary Incontinence | The Cleveland Clinic | COMPLETED | PHASE3 | INTERVENTIONAL | null | null | Stress Urinary Incontinence | TVT-SECUR device, tension-free vaginal tape | null | academic | completed | urology | urology |
NCT05009004 | Digital Health for Medication Adherence Among African Americans With Hypertension | Environment and Health Group, Inc. | COMPLETED | NA | INTERVENTIONAL | 2022-10-14 | 2023-06-23 | Hypertension | text messages to support medication adherence | 0 | industry | completed | cardiovascular | cardiovascular |
NCT05741853 | Cognitive Reserve and Linguistic Resilience in Bilingual Hispanics With Primary Progressive Aphasia | University of Texas at Austin | RECRUITING | NA | INTERVENTIONAL | 2023-05-01 | 2027-11-30 | Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia | Lexical Retrieval Training (LRT), Video-Implemented Script Training for Aphasia (VISTA) | 0 | academic | active | neurology | neurology |
NCT05955209 | An Open, Single Arm, Single Center Phase II Clinical Study Evaluating the Efficacy and Safety of RC48-ADC in the Treatment of Metastatic Castration Resistant Prostate Cancer (mCRPC) Progression After Novel Endocrine Therapy | Peking University Cancer Hospital & Institute | UNKNOWN | PHASE2 | INTERVENTIONAL | 2023-08-01 | 2024-08-01 | Metastatic Castration-resistant Prostate Cancer | Disitamab Vedotin（RC48-ADC） | 0 | academic | unknown | oncology | oncology |
NCT03087396 | A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle | Zimmer Biomet | COMPLETED | OBSERVATIONAL | 2017-03-10 | 2023-08-23 | Insufficiency Fractures, Stress Fracture, Stress Fracture, Ankle, Foot and Toes | Treatment of insufficiency fractures | 0 | other | completed | null | null | |
NCT03269461 | Serial OCT Evaluation of Tissue Coverage in Patients Submitted to Inspiron Drug Eluting Stent Implantation | Scitech Produtos Medicos Ltda | COMPLETED | NA | INTERVENTIONAL | 2017-10-02 | 2018-12-30 | Coronary Artery Disease | Angiography and Optical Coherence Tomography evaluations | 0 | industry | completed | cardiovascular | cardiovascular |
NCT03233230 | A Phase IIb, Randomized, Double-blind Study in Subjects With Rheumatoid Arthritis Evaluating the Safety and Efficacy of Evobrutinib Compared With Placebo in Subjects With an Inadequate Response to Methotrexate | EMD Serono Research & Development Institute, Inc. | COMPLETED | PHASE2 | INTERVENTIONAL | 2017-09-18 | 2019-09-23 | Rheumatoid Arthritis | M2591 25 mg QD, M2951 50 mg BID, M2951 75 mg QD, Placebo | 0 | industry | completed | immunology | immunology |
NCT01627613 | Proof of Concept Study in Male and Female Intensive Care Patients to Investigate the Clinical Effect of Repetitive Orally Inhaled Doses of AP301 on Alveolar Liquid Clearance in Acute Lung Injury | Apeptico Forschung und Entwicklung GmbH | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Acute Lung Injury | AP301, Saline solution | null | industry | completed | null | null |
NCT03024424 | Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMD | University of Utah | COMPLETED | NA | INTERVENTIONAL | null | 2017-08-10 | Age-Related Macular Degeneration, Choroidal Neovascularization, Genetic Counseling | Early disclosure, Late disclosure | null | academic | completed | ophthalmology | ophthalmology |
NCT00508222 | A Pilot, Prospective, Open-label Study to Evaluate the Safety and Efficacy of Kaletra® Monotherapy in HIV/HCV Co-infected Subjects. | Ottawa Hospital Research Institute | COMPLETED | PHASE3 | INTERVENTIONAL | null | null | HIV Infections | Kaletra Tablets | null | academic | completed | infectious_disease | infectious_disease |
NCT05784662 | Evaluating the Social Workers Addressing Firearm Risk (SAFR) Intervention: A Pilot Study | State University of New York at Buffalo | COMPLETED | NA | INTERVENTIONAL | 2023-08-21 | 2024-05-31 | Gun Violence Prevention | Social Workers Addressing Firearm Risk | 0 | academic | completed | null | null |
NCT02311218 | Oral Microbiota Shift After 12-week Supplementation With Lactobacillus Reuteri DSM 17938 and PTA 5289 | Umeå University | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Dental Plaque | Lactobacillus reuteri DSM 17938 and PTA 5289, Placebo | null | academic | completed | null | other |
NCT05878574 | Prospective Cohort Study of Bone Mineral Density and Calcium-phosphorus Metabolism in RSA Patients: Low Molecular Weight Heparin Use Versus Control | Aimin Zhao | UNKNOWN | OBSERVATIONAL | 2022-11-01 | null | Recurrent Spontaneous Abortion | Low molecular weight heparin | null | other | unknown | null | null | |
NCT03614039 | Effect of Alive Probiotics Supplementation With Absorbent Smectite Gel in NAFLD | Nazarii Kobyliak | COMPLETED | NA | INTERVENTIONAL | 2015-09-15 | 2016-03-15 | Non-Alcoholic Fatty Liver Disease, Fatty Liver, Liver Diseases, Digestive System Diseases, Type2 Diabetes | "Symbiter Forte", Placebo | 0 | other | completed | gastroenterology | gastroenterology; metabolic; psychiatry |
NCT01620398 | The Brazilian Cardioprotective Nutritional Program to Reduce Events and Risk Factors in Secondary Prevention for Cardiovascular Disease | Hospital do Coracao | COMPLETED | NA | INTERVENTIONAL | 2013-03-05 | null | Cardiovascular Diseases | BALANCE, Control diet | null | academic | completed | cardiovascular | cardiovascular |
NCT01601938 | Effects of Selenium Replacement on Prognosis of Severe Sepsis and Septic Shock Patients and Their Initial Serum Selenium Level: a Randomized, Double-blind Placebo Controlled Phase 2 Study | Gil Joon Suh | WITHDRAWN | PHASE2 | INTERVENTIONAL | null | null | Sepsis, Shock, Septic | Placebo, selenium replacement | null | other | failed | infectious_disease | infectious_disease; other |
NCT03053973 | Nocturnal Non-Invasive Ventilation in COPD Patients With Stable Hypercapnic Respiratory Failure: Why and in Which Patient Might This be Effective? | Peter Wijkstra | UNKNOWN | NA | INTERVENTIONAL | 2017-11-13 | 2025-08-01 | Noninvasive Ventilation | Standard Care, nocturnal noninvasive ventilation | 0 | other | unknown | null | null |
NCT04840303 | The Effectiveness and Cost-effectiveness of Mental Wellness Youth Hubs | The University of Hong Kong | UNKNOWN | NA | INTERVENTIONAL | 2019-11-01 | 2024-04-30 | Mental Stress | LevelMind@JC Mental Wellness Youth Hubs | 0 | academic | unknown | null | null |
NCT06500364 | Knotless Implants As an Alternative for Capsular Closure in Primary Hip Arthroscopy: a Prospective, Multi-Center Study | American Hip Institute | RECRUITING | PHASE4 | INTERVENTIONAL | 2024-10-29 | null | Femoro Acetabular Impingement | Control Arm, LoopLoc Arm | null | academic | active | null | null |
NCT02023775 | Non Interventional Study on Pulmonary Valve Replacement by Thranscatheter Pulmonary Valve Melody™ | Medtronic Cardiac Rhythm and Heart Failure | COMPLETED | OBSERVATIONAL | 2010-01-31 | 2013-01-24 | Right Ventricular Congenital Cardiopathies | Melody valve implantation | 0 | other | completed | null | null | |
NCT03288870 | International Multi-center Open-label Randomized Clinical Trial of Efficacy, Safety and Pharmacokinetics of BCD-100 (JSC "BIOCAD", Russia) Monotherapy Compared to Docetaxel as Second-line Therapy of Patients With Advanced Inoperable or Metastatic Non-small Cell Lung Cancer | Biocad | UNKNOWN | PHASE2, PHASE3 | INTERVENTIONAL | 2017-09-19 | 2020-08-10 | Non Small Cell Lung Cancer Stage IIIB, Non-Small Cell Carcinoma of Lung, TNM Stage 4 | BCD-100, Docetaxel | 0 | other | unknown | null | null |
NCT06168461 | Aspirin for the Treatment of Vascular Dysfunction After Preeclampsia | Anna Stanhewicz, PhD | RECRUITING | EARLY_PHASE1 | INTERVENTIONAL | 2023-11-01 | null | Preeclampsia | Aspirin, Placebo | null | other | active | reproductive | reproductive |
NCT00993941 | Evaluation the Efficacy and Safety of Autologous Bone Marrow Mesenchymal Stem Cells (MSCs) Transplantation in Patients With Early and Middle Stage of Liver Cirrhosis | Sun Yat-sen University | UNKNOWN | PHASE2 | INTERVENTIONAL | null | null | Liver Cirrhosis | Autologous BMSCs transplantation, Conserved therapy | null | academic | unknown | gastroenterology | gastroenterology |
NCT04874857 | The Effect of Aromatherapy Massage Applied to Hemodialysis Patients With Muscle Cramp on Cramp Frequency, Severity of Pain and Quality of Life | TC Erciyes University | COMPLETED | NA | INTERVENTIONAL | 2020-11-25 | 2022-12-28 | Muscle Cramps, Aromatherapy, Hemodialysis, Quality of Life, Pain | Baby oil, Lavandula angustifolia, Rosmarinus officinalis L. and Origanum majorana L. | 0 | academic | completed | musculoskeletal | musculoskeletal; nephrology; other |
NCT02928744 | Evaluation of the Reversibility of the Bronchial Obstruction by Impulse Oscillometry Technique in Chronic Obstructive Pulmonary Disease (COPD): Correlation With Functional Features Measured by Plethysmography and Dyspnoea | Hopital Foch | TERMINATED | NA | INTERVENTIONAL | null | null | COPD | COPD | null | other | failed | respiratory | respiratory |
NCT06648798 | LIMBER UniLeg: Rapid, On-demand, and Scaled-up Manufacturing of Customized Transtibial Prosthetic Legs for Amputees | LIMBER Prosthetics & Orthotics Inc | RECRUITING | NA | INTERVENTIONAL | 2023-12-20 | 2025-10-31 | Amputation of Lower Limb, Prosthesis, Non-inferiority Trial of Prothesis | Limber Limb | 0 | industry | active | null | null |
NCT02863211 | The Assessment of Large and Small Artery Elasticity for the Early Detection of Cardiovascular Disease | St. Boniface Hospital | UNKNOWN | OBSERVATIONAL | null | null | Cardiovascular Diseases, Vascular Stiffness | null | academic | unknown | cardiovascular | cardiovascular | ||
NCT02093091 | Two-year Clinical Performance in Primary Teeth of Nano-filled Versus Conventional Resin Modified Glass Ionomer Restorations | Tanta University | COMPLETED | NA | INTERVENTIONAL | null | null | Dental Caries | Dental caries was removed from primary molars and was filled with the conventional filling material;Vitremer, Dental caries was removed from primary molars and was filled with the recent filling material; Ketac Nano. | null | academic | completed | null | other |
NCT04044781 | A Phase 1, Open-Label, Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of BPN14770 | Tetra Discovery Partners | WITHDRAWN | PHASE1 | INTERVENTIONAL | 2020-01-10 | 2020-04-30 | To Determine Brain Target Occupancy of BPN14770 | BPN14770, T2310 | 0 | other | failed | null | null |
NCT04138264 | Opioid Consumption After Orthopaedic Surgery: Prospective Randomized Trial on the Effects of Pre-Operative Counseling | Rothman Institute Orthopaedics | COMPLETED | NA | INTERVENTIONAL | 2018-06-19 | 2018-11-02 | Orthopedic Disorder | Preoperative opioid counseling | 0 | academic | completed | null | null |
NCT02572245 | A Phase 1, Open-label, Randomized, Single Dose, Parallel Group Comparability Study To Assess The Pharmacokinetics Of Pf-06410293 Following Subcutaneous Administration Using A Prefilled Syringe Or A Prefilled Pen In Healthy Adult Subjects | Pfizer | COMPLETED | PHASE1 | INTERVENTIONAL | null | null | Healthy Subjects | PF-06410293 PFP, PF-06410293 PFS | null | industry | completed | healthy_volunteers | healthy_volunteers |
NCT06797245 | The APPROVE Trial: A Randomized Controlled Trial Evaluating the Efficacy and Safety of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women | Medstar Health Research Institute | RECRUITING | NA | INTERVENTIONAL | 2025-03-17 | null | Overactive Bladder (OAB), Urinary Urgency, Urinary Urge Incontinence (UUI), Nocturia, Urinary Frequency | AUGS Patient Handouts, RiSolve App | null | academic | active | urology | urology |
NCT03966456 | Real World Study of Immunotherapy-Comparison of Four PD-1 Agents in China | The Affiliated Hospital of Qingdao University | UNKNOWN | OBSERVATIONAL | 2018-06-01 | 2021-06-01 | Thoracic Cancer, Gynecologic Cancer, Abdomen Tumors, Malignant Melanoma | Chemotherapy | 0 | academic | unknown | oncology | oncology | |
NCT05164250 | Compassionate Use (CU) of REGN5458 for Patients With Relapsed or Refractory Multiple Myeloma (MM) | Regeneron Pharmaceuticals | APPROVED_FOR_MARKETING | EXPANDED_ACCESS | null | null | Multiple Myeloma | REGN5458 | null | industry | other | oncology | oncology | |
NCT00140933 | A Randomized, Double-Blind, 7-Day Study of the Efficacy and Safety of Rofecoxib Versus Placebo and Diclofenac in Patients With Acute Painful Rotator Cuff Syndrome | Merck Sharp & Dohme LLC | TERMINATED | PHASE3 | INTERVENTIONAL | null | null | Pain | Comparator: diclofenac, placebo, MK0966; rofecoxib | null | industry | failed | musculoskeletal | musculoskeletal |
NCT00510380 | Epigenetic Markets in Growth Restricted Human Pregnancies: A Case- Control Study | National University Hospital, Singapore | COMPLETED | OBSERVATIONAL | null | null | Fetal Growth Retardation | null | academic | completed | null | null | ||
NCT03834194 | Effect of Incentives for Self-weighing, Weight Management Goals and Physical Activity Goals on Gaining Weight Healthily During Pregnancy | University of Tennessee | COMPLETED | NA | INTERVENTIONAL | 2019-02-26 | 2020-04-09 | Gestational Weight Gain | Loss + Monthly Weight, Loss + Monthly Weight + Exercise, Loss + Overall Weight, Loss + Overall Weight + Exercise, Lottery + Monthly Weight, Lottery + Monthly Weight + Exercise, Lottery + Overall Weight, Lottery + Overall Weight + Exercise | 0 | academic | completed | metabolic | metabolic |
NCT00246428 | Motivational Interviewing (MI) for ETOH+ Teens in the ER | Brown University | COMPLETED | PHASE3 | INTERVENTIONAL | 2003-01-01 | 2008-01-31 | Alcohol Abuse, Alcohol Dependence | Individual Motivational Interview (IMI), Individual Motivational Interview + Family Check-Up | 0 | academic | completed | psychiatry | psychiatry |
NCT03767920 | Role of Co-administered Dexamethasone in Transversus Abdominis Plane Block After Cesarean Section: A Randomized, Double-blind Controlled Trial | Aswan University Hospital | COMPLETED | NA | INTERVENTIONAL | 2019-01-01 | 2020-03-30 | Cesarean Section | bupivacaine, dexamethasone, placebo to dexamethasone | 0 | academic | completed | reproductive | reproductive |
NCT07252674 | Impact of Laryngeal Mask Airway Versus Endotracheal Intubation on Mechanical Power and Postoperative Respiratory Complications in Pediatric Patients: A Prospective Observational Study | Konya City Hospital | RECRUITING | OBSERVATIONAL | 2025-11-30 | 2026-02-20 | Mechanical Power | Laryngeal Mask Airway (LMA) | 0 | academic | active | null | null | |
NCT01334944 | A Multi-Center, Open-Label, Surveillance Trial To Evaluate The Safety and Efficacy of a Shortened Infusion Time of Intravenous Ibuprofen. | Cumberland Pharmaceuticals | COMPLETED | PHASE4 | INTERVENTIONAL | null | null | Pain, Fever | Intravenous ibuprofen | null | industry | completed | infectious_disease | infectious_disease; musculoskeletal |
NCT02134171 | Identification of Early Predictive Factors of Cardiac and Cerebral Involvement in Thrombotic Microangiopathies | Assistance Publique - Hôpitaux de Paris | COMPLETED | NA | INTERVENTIONAL | 2014-06-10 | 2017-07-04 | Thrombotic Microangiopathies, Thrombotic Thrombocytopenic Purpura | Biological and imaging investigations | 0 | academic | completed | null | null |
NCT05778916 | Radiological Outcome vs.Patient Reported Clinical Outcome 5 Years Post Hallux Valgus Surgery | Ostfold Hospital Trust | UNKNOWN | OBSERVATIONAL | 2023-04-12 | 2024-04-12 | Hallux Valgus | 5 year follow up on patients operated for hallux valgus deformity | 0 | academic | unknown | null | null | |
NCT06110000 | Effects of Pragmatic Set of Interventions Versus Scapular Strengthening Exercises on Scapular Dyskinesia in Adhesive Capsulitis | Riphah International University | UNKNOWN | NA | INTERVENTIONAL | 2023-05-08 | 2023-12-08 | Scapular Dyskinesis, Adhesive Capsulitis | pragmatic set of interventipons, scapular strengthening exercise. | 0 | academic | unknown | dermatology | dermatology |
NCT00077896 | Direct Current Brain Polarization in Frontotemporal Dementia | National Institute of Neurological Disorders and Stroke (NINDS) | COMPLETED | PHASE1 | INTERVENTIONAL | null | null | Pick Disease of the Brain | Direct Current Polarization | null | academic | completed | null | null |
NCT05379439 | Family Connections: Structured Family Deliberation for Decisions About Home Ventilation | Johns Hopkins All Children's Hospital | WITHDRAWN | NA | INTERVENTIONAL | 2022-07-01 | 2022-10-05 | Chronic Respiratory Failure | Structured Family Deliberation | 0 | academic | failed | null | null |
NCT00943098 | Efficacy and Safety of a Single s.c. Diclofenac HPBCD 75mg/1ml Injection as Compared to a Single i.m. Voltarol® 75mg/3ml, in the Treatment of Acute Moderate-to-severe Post-surgical Pain Following Dental Surgery (Impacted 3rd Molar Removal). | IBSA Institut Biochimique SA | COMPLETED | PHASE3 | INTERVENTIONAL | null | null | Dental Pain | Diclofenac HPBCD s.c. 75mg/ml, Voltarol 75mg/3ml i.m. | null | other | completed | null | null |
NCT04602013 | A Prospective, Multi-center, Single-arm Clinical Study of Sintilimab Injection Combined With Concurrent Radiotherapy and Chemotherapy in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma (IMCORT) | Sichuan Cancer Hospital and Research Institute | UNKNOWN | PHASE2 | INTERVENTIONAL | 2020-10-11 | null | Locally Advanced Esophageal Squamous Cell Carcinoma | Chemotherapy, Radiation Therapy, Sintilimab | null | academic | unknown | null | null |
NCT00003460 | Phase II Study of Antineoplastons A10 and AS2-1 In Children With Primitive Neuroectodermal Tumors | Burzynski Research Institute | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Childhood CNS Primitive Neuroectodermal Tumor | Antineoplaston therapy (Atengenal + Astugenal) | null | academic | completed | null | null |
NCT06681259 | Clinical Specialty Queue For Gestational Trophoblastic Neoplasia | Women's Hospital School Of Medicine Zhejiang University | RECRUITING | OBSERVATIONAL | 2024-11-04 | 2029-11-04 | Gestational Trophoblastic Neoplasia | 0 | academic | active | null | null | ||
NCT06567288 | Effeect of Spencer Muscle Energy Technique on Pain in Diabetic Stiff Shoulder | Cairo University | NOT_YET_RECRUITING | NA | INTERVENTIONAL | 2024-10-01 | 2024-11-01 | Frozen Shoulder | spencer mscle energy technique | 0 | academic | active | null | null |
NCT06555874 | Evaluation of the MORENO Score for the Regulation of Secondary Transfers to the UAS-SMUR in Brest in Finistère in 2020 | University Hospital, Brest | COMPLETED | OBSERVATIONAL | 2020-06-01 | 2021-06-30 | the Safety / Feasibility /MORENO Score/Regulation / Secondary Transfers / SAMU 29 / Current Practices | 0 | academic | completed | null | null | ||
NCT04972539 | A Randomized, Open, Single-dose, 2x2 Crossover Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics After Co-administration of A51R1 and A51R2 or Administration of AJU-A51 in Healthy Volunteers Under Fasting Conditions | AJU Pharm Co., Ltd. | COMPLETED | PHASE1 | INTERVENTIONAL | 2020-08-01 | 2020-11-30 | Diabetes Mellitus, Type 2 | A51R1 Tab. and A51R2 Tab., AJU-A51 Tab. | 0 | industry | completed | metabolic | metabolic |
NCT06671197 | Multicenter Randomized Controlled Study on Efficacy and Safety of Pulmonary Vein Isolation,Left Atrial Posterior Wall Ablation and Superior Vena Cava Isolation Using Pulsed Field Ablation for Persistent Atrial Fibrillation | Second Affiliated Hospital, School of Medicine, Zhejiang University | NOT_YET_RECRUITING | OBSERVATIONAL | 2025-03-31 | 2027-03-31 | Persistent Atrial Fibrillation | Pulmonary vein isolation, Pulmonary vein isolation+posterior left atrial wall line+superior vena cava isolation | 0 | academic | active | cardiovascular | cardiovascular | |
NCT05993065 | Study of Hematocrit to Hemoglobin Ratio and Red Blood Cell Distribution Width in Polycythemia Vera and Secondary Erythrocytosis | Sohag University | UNKNOWN | OBSERVATIONAL | 2022-12-15 | null | Polycythemia Vera | null | academic | unknown | hematology | hematology | ||
NCT02773550 | Clinical, Multicenter, Single-arm, Treatment With a Scheme With Low Doses of Bortezomib / Melphalan / Prednisone (MPV) in Patients With Multiple Myeloma (MM) Newly Diagnosed Symptomatic ≥75 Years | Basque Health Service | TERMINATED | PHASE4 | INTERVENTIONAL | null | null | Multiple Myeloma | Bortezomib, Melphalan, Prednisone | null | other | failed | oncology | oncology |
NCT00646659 | Randomized Phase II Feasibility Study of Cetuximab Combined With 4 Cycles of TPF Followed by Platinum Based Chemo-radiation Strategies | European Organisation for Research and Treatment of Cancer - EORTC | TERMINATED | PHASE2 | INTERVENTIONAL | null | null | Head and Neck Cancer | 3-dimensional conformal radiation therapy, biopsy, carboplatin, cetuximab, cisplatin, docetaxel, fluorescence in situ hybridization, fluorouracil, immunoenzyme technique, immunohistochemistry staining method, intensity-modulated radiation therapy, laboratory biomarker analysis, molecular genetic technique, reverse tran... | null | other | failed | oncology | oncology |
NCT06189118 | Online Mindfulness-Based Cognitive Therapy vs Health Enhancement Program for Depressive Symptoms in Older Adults: a Randomized Controlled Trial | Lady Davis Institute | COMPLETED | NA | INTERVENTIONAL | 2023-09-01 | 2024-12-31 | Older Age; Depression | Online Mindfulness Based Cognitive Therapy or Health Education Program | 0 | academic | completed | null | null |
NCT06698081 | The Effect of Using Multimedia During the Informed Consent Process on the Anxiety of Parents of Orchiopexy Patients: a Randomized Controlled Trial | Marmara University | RECRUITING | NA | INTERVENTIONAL | 2024-11-20 | 2025-03-25 | Undescended Testis, Anxiety State | Video Multimedia | 0 | academic | active | psychiatry | psychiatry |
NCT04056988 | Utilizing Contrast-enhanced Ultrasound (CEUS) to Assess Critically Hypo Perfused Spinal Cord Tissue After Injury | University of Washington | COMPLETED | PHASE4 | INTERVENTIONAL | 2018-07-31 | 2023-11-20 | Acute Spinal Cord Injury | Perflutren Lipid Microsphere | 0 | academic | completed | null | null |
NCT04108403 | Mechanisms of Massage | University of Florida | COMPLETED | NA | INTERVENTIONAL | 2019-10-31 | 2021-12-15 | Healthy, Pain | Negative Expectation Instructional Set, Pain Free Massage, Pain Inducing Massage, Positive Expectation Instructional Set | 0 | academic | completed | healthy_volunteers | healthy_volunteers; musculoskeletal |
NCT07019857 | Impact of Thymectomy on Immune Response in Infants 12 Months After Cardiac Surgery: a Single-centre Prospective Study | Nantes University Hospital | NOT_YET_RECRUITING | NA | INTERVENTIONAL | 2025-09-01 | 2027-12-01 | Congenital Heart Defects, Thymectomy, Immunological Deficiency Syndrome | Blood sample collection at surgery time and 12 months later | 0 | academic | active | null | null |
NCT05395117 | A Fixed Sequence, Open-label Study to Assess the Effect of Multiple Doses of AZD5462 on the Pharmacokinetics of Oral Midazolam (CYP3A4 Probe), Rosuvastatin (OATP1B1/3, BCRP Probe), and Digoxin (P-gp Probe) in Healthy Participants | AstraZeneca | COMPLETED | PHASE1 | INTERVENTIONAL | 2022-06-30 | 2022-09-12 | Healthy Participants | AZD5462, Digoxin, Midazolam, Rosuvastatin | 0 | industry | completed | healthy_volunteers | healthy_volunteers |
NCT01502046 | A Double Blind, Randomized, Cross Over, Placebo Controlled Phase 2 Clinical Trial to Asses Neuroprotection by Cannabinoids in Huntington's Disease | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Huntington's Disease | Placebo, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) | null | academic | completed | neurology | neurology |
NCT04923087 | Impact of Auditory Stimulation in Eating Pleasure : Multicentric Study With Biscuits With Crunchy Texture vs Soft Texture in 100 Seniors Affected or at Risk of Presbyacusis | Centre Hospitalier Universitaire de Nice | UNKNOWN | OBSERVATIONAL | 2021-06-01 | 2021-08-31 | Frailty, Malnutrition, Anorexia, Presbycusis, Edentulism Nos | Compare the noise and pleasure of crunching between two hyperprotein nutritional supplements | 0 | academic | unknown | metabolic | metabolic; other; psychiatry | |
NCT05476263 | Non-interventional, Observational, Prospective, Multicentre Study in a Routine Clinical Care Setting Using a Marketed Medical Device in Line With the Corresponding IFU in the Intended Patient Population | Lohmann & Rauscher | RECRUITING | OBSERVATIONAL | 2024-06-03 | null | Esophagus Injury, Rectal Lesion | null | other | active | null | null | ||
NCT03372226 | Computer-based Self-Help Program for People With Gambling Problems | Universitätsklinikum Hamburg-Eppendorf | COMPLETED | NA | INTERVENTIONAL | 2018-01-18 | 2018-12-09 | Gambling, Pathologic | Online self-help program | 0 | other | completed | null | null |
NCT06480630 | Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases | Anhui Provincial Hospital | NOT_YET_RECRUITING | PHASE2 | INTERVENTIONAL | 2024-07-01 | 2026-06-30 | Acute Graft Versus Host Disease, Malignant Hematologic Neoplasm | Basiliximab | 0 | industry | active | immunology | immunology |
NCT00802594 | Phase II A Trial of DB289 for the Treatment of Stage I African Trypanosomiasis | Immtech Pharmaceuticals, Inc | COMPLETED | PHASE2 | INTERVENTIONAL | null | null | Trypanosomiasis, African | DB289 | null | industry | completed | null | null |
NCT03471663 | A Phase I, Open-Label Study of D-0502 Single Agent and D-0502 in Combination With Palbociclib in Women With Advanced or Metastatic ER-Positive and HER2-Negative Breast Cancer | InventisBio Co., Ltd | COMPLETED | PHASE1 | INTERVENTIONAL | 2018-03-18 | 2023-10-18 | Breast Cancer | D-0502, palbociclib | 0 | industry | completed | oncology | oncology |
NCT02163408 | 3D Multi-Contrast Atherosclerosis Characterization of the Carotid Artery | Cedars-Sinai Medical Center | COMPLETED | OBSERVATIONAL | 2014-06-24 | 2022-04-25 | Carotid Artery Disease | MRI with/without contrast | 0 | academic | completed | null | null | |
NCT06892262 | Relationship Between FMS and Trunk Muscle Strength, Balance, Body Composition. | Gazi University | COMPLETED | NA | INTERVENTIONAL | null | null | Healthy Athletes | Athletes | null | academic | completed | null | null |
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