---
license: apache-2.0
tags:
  - biology
  - protein-structure-prediction
  - protenix
  - mirror
---

# Protenix v0.5.0 base checkpoint (unmodified mirror)

The base checkpoint of [ByteDance Protenix](https://github.com/bytedance/Protenix) v0.5.0, byte
for byte as upstream published it. Not retrained, not quantised, not converted, not modified in
any way.

| | |
|---|---|
| File | `model_v0.5.0.pt` |
| Size | 1,474,265,486 bytes |
| sha256 | `9ea20b0aba42f2256711da1d0cd081510a4b291e64375bff6b70ced70b87a5f1` |
| Upstream URL | `https://af3-dev.tos-cn-beijing.volces.com/release_model/model_v0.5.0.pt` |
| Upstream code | [bytedance/Protenix](https://github.com/bytedance/Protenix), tag `v0.5.0` |
| Licence | Apache 2.0, ByteDance. Full text in `LICENSE`. |

## What it is

Weights for Protenix, an open reproduction of AlphaFold 3 that predicts the 3D structure of
proteins, nucleic acids and their complexes with ligands. The upstream URL above is the one
`protenix/web_service/dependency_url.py` names at tag `v0.5.0`.

## Why this mirror exists

Upstream serves this file from a single Volcengine bucket in Beijing. A network that cannot route
there gets a TCP connection that is accepted and then sends nothing, so an install hangs rather
than failing. This copy is the same bytes from a host that answers from anywhere. Upstream stays
the fallback, not the only door.

Published so [tt-bio](https://github.com/moritztng/tt-bio) can fetch it, which runs Protenix on
Tenstorrent accelerators. Nothing about the file is tt-bio specific: any Protenix install can use
it.

## Verify before you trust it

```bash
sha256sum model_v0.5.0.pt
# 9ea20b0aba42f2256711da1d0cd081510a4b291e64375bff6b70ced70b87a5f1
```

That hash was taken from a fresh upstream download and compared against this copy.

## Use it

With tt-bio, nothing to do: `tt-bio predict --model protenix-v1 <fasta>` fetches from here.

By hand, for an upstream Protenix install:

```bash
huggingface-cli download moritztng/protenix-v0.5.0 model_v0.5.0.pt --local-dir .
```

## Attribution

Copyright 2024 ByteDance and/or its affiliates, licensed under Apache 2.0. Redistributed under
section 4 of that licence: the licence text travels with the file, the notices in it are
unchanged, and this file is unmodified.