Daily Papers

High-dimensional point cloud data arise across many scientific domains, especially single-cell biology. The shapes or topologies of these datasets determine the types of information that can be extracted. For example, clustered data supports cell-type identification, trajectory structures support transition analysis, and archetypal structures capture continua of cellular behaviors. Existing analysis pipelines often assume a specific shape. The standard Seurat pipeline combines UMAP visualization with Louvain clustering and therefore assumes clustered data, while tools such as Monocle and SPADE assume tree-like structures, and flow-based models such as MIOFlow and Conditional Flow Matching target trajectories. Choosing which pipeline to apply is therefore often left to bioinformaticians who visually inspect datasets before selecting an analysis strategy. With the rise of agentic AI scientists, automating shape detection is increasingly important for selecting downstream analysis pipelines. To address this problem, we introduce scShapeBench, a benchmark dataset for shape detection containing both synthetic and expert-annotated single-cell datasets. Synthetic datasets are sampled from ground-truth skeleton graphs with controlled variance. Real single-cell datasets are curated from diverse sources and annotated by experts into four categories: clusters, single trajectory, multi-branching, and archetypal. We additionally introduce scReebTower, a baseline method that uses diffusion geometry to extract Reeb graphs and connect visualization with pipeline selection. We provide topology-aware evaluation metrics and compare scReebTower against PAGA and Mapper on synthetic and real data. Our results indicate that scReebTower outperforms existing baselines. Overall, our contributions span benchmarks, evaluation metrics, and a baseline for automated shape detection in single-cell data.

Pixel-level segmentation of structural cracks across various scenarios remains a considerable challenge. Current methods encounter challenges in effectively modeling crack morphology and texture, facing challenges in balancing segmentation quality with low computational resource usage. To overcome these limitations, we propose a lightweight Structure-Aware Vision Mamba Network (SCSegamba), capable of generating high-quality pixel-level segmentation maps by leveraging both the morphological information and texture cues of crack pixels with minimal computational cost. Specifically, we developed a Structure-Aware Visual State Space module (SAVSS), which incorporates a lightweight Gated Bottleneck Convolution (GBC) and a Structure-Aware Scanning Strategy (SASS). The key insight of GBC lies in its effectiveness in modeling the morphological information of cracks, while the SASS enhances the perception of crack topology and texture by strengthening the continuity of semantic information between crack pixels. Experiments on crack benchmark datasets demonstrate that our method outperforms other state-of-the-art (SOTA) methods, achieving the highest performance with only 2.8M parameters. On the multi-scenario dataset, our method reached 0.8390 in F1 score and 0.8479 in mIoU. The code is available at https://github.com/Karl1109/SCSegamba.

Channel and spatial attentions have respectively brought significant improvements in extracting feature dependencies and spatial structure relations for various downstream vision tasks. While their combination is more beneficial for leveraging their individual strengths, the synergy between channel and spatial attentions has not been fully explored, lacking in fully harness the synergistic potential of multi-semantic information for feature guidance and mitigation of semantic disparities. Our study attempts to reveal the synergistic relationship between spatial and channel attention at multiple semantic levels, proposing a novel Spatial and Channel Synergistic Attention module (SCSA). Our SCSA consists of two parts: the Shareable Multi-Semantic Spatial Attention (SMSA) and the Progressive Channel-wise Self-Attention (PCSA). SMSA integrates multi-semantic information and utilizes a progressive compression strategy to inject discriminative spatial priors into PCSA's channel self-attention, effectively guiding channel recalibration. Additionally, the robust feature interactions based on the self-attention mechanism in PCSA further mitigate the disparities in multi-semantic information among different sub-features within SMSA. We conduct extensive experiments on seven benchmark datasets, including classification on ImageNet-1K, object detection on MSCOCO 2017, segmentation on ADE20K, and four other complex scene detection datasets. Our results demonstrate that our proposed SCSA not only surpasses the current state-of-the-art attention but also exhibits enhanced generalization capabilities across various task scenarios. The code and models are available at: https://github.com/HZAI-ZJNU/SCSA.