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  1. README.md +38 -0
  2. adbahadosingh.pt +3 -0
  3. config.json +35 -0
README.md ADDED
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+ ---
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+ license: bsd-3-clause
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+ library_name: pyaging
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+ tags:
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+ - pyaging
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+ - aging-clock
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+ - biology
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+ - dna-methylation
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+ ---
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+
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+ # adbahadosingh
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+
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+ PyAging implements the paper’s conventional four-CpG logistic-regression equation and applies a sigmoid to return LOAD case probability; it does not implement the separate high-dimensional deep-learning classifiers also evaluated in the paper.
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+
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+ | | |
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+ |---|---|
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+ | **Predicts** | late-onset Alzheimer's disease |
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+ | **Species** | Homo sapiens |
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+ | **Tissue** | whole blood |
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+ | **Data type** | DNA methylation |
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+ | **Model type** | logistic regression |
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+ | **Year** | 2021 |
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+
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+ ## Use with pyaging
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+
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+ ```python
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+ import pyaging as pya
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+
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+ pya.pred.predict_age(adata, ["adbahadosingh"])
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+ ```
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+
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+ Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
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+
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+ ## Citation
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+
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+ Bahado-Singh, R. O., Vishweswaraiah, S., Aydas, B., et al. (2021). Artificial intelligence and leukocyte epigenomics: Evaluation and prediction of late-onset Alzheimer's disease. PLOS ONE, 16(4), e0248375.
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+
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+ https://doi.org/10.1371/journal.pone.0248375
adbahadosingh.pt ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:43502e4a45b0d8113617641a3e3d3cfae8541a9c7d438b11c4f8ddc1dfd28b1d
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+ size 4837
config.json ADDED
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+ {
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+ "approved_by_author": "\u231b",
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+ "citation": "Bahado-Singh, R. O., Vishweswaraiah, S., Aydas, B., et al. (2021). Artificial intelligence and leukocyte epigenomics: Evaluation and prediction of late-onset Alzheimer's disease. PLOS ONE, 16(4), e0248375.",
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+ "citations": 33,
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+ "citations_date": "2026-07-05",
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+ "clock_name": "adbahadosingh",
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+ "data_type": "DNA methylation",
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+ "doi": "https://doi.org/10.1371/journal.pone.0248375",
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+ "journal": "PLOS ONE",
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+ "last_author": "Uppala Radhakrishna",
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+ "model_type": "logistic regression",
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+ "n_features": 4,
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+ "notes": "PyAging implements the paper\u2019s conventional four-CpG logistic-regression equation and applies a sigmoid to return LOAD case probability; it does not implement the separate high-dimensional deep-learning classifiers also evaluated in the paper.",
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+ "platform": [
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+ "Illumina EPIC"
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+ ],
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+ "population": "older adults",
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+ "postprocess": "sigmoid",
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+ "predicts": [
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+ "late-onset Alzheimer's disease"
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+ ],
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+ "research_only": null,
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+ "species": "Homo sapiens",
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+ "tissue": [
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+ "whole blood"
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+ ],
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+ "training_target": [
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+ "late-onset Alzheimer's disease"
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+ ],
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+ "unit": [
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+ "probability"
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+ ],
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+ "version": "v0.3.0",
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+ "year": 2021
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+ }