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"approved_by_author": "\u2705",
"citation": "de Lima Camillo, L. P., Asif, M. H., Horvath, S., Larschan, E., & Singh, R. Histone mark age of human tissues and cell types. Science Advances 11, eadk9373 (2025).",
"citations": 33,
"citations_date": "2026-10-02",
"clock_name": "camilloh3k27me3",
"data_type": "histone modification",
"doi": "https://doi.org/10.1126/sciadv.adk9373",
"journal": "Science Advances",
"last_author": "Ritambhara Singh",
"model_type": "PCA + elastic net + ARD regression",
"n_features": 922,
"notes": "Pan-tissue chronological-age predictor trained on gene-level H3K27me3 ChIP-seq enrichment; ElasticNet feature selection is followed by truncated-SVD PCA and automatic relevance determination regression.",
"platform": [
"ChIP-seq"
],
"population": "all ages",
"predicts": [
"chronological age"
],
"research_only": null,
"species": "Homo sapiens",
"tissue": [
"multi-tissue"
],
"training_target": [
"chronological age"
],
"unit": [
"years"
],
"version": "0.5.7",
"year": 2025
} |