| { | |
| "approved_by_author": "\u231b", | |
| "citation": "Shireby, G. L., et al. \"Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.\" Brain 143.12 (2020): 3763-3775.", | |
| "citations": 216, | |
| "citations_date": "2026-10-02", | |
| "clock_name": "corticalclock", | |
| "data_type": "DNA methylation", | |
| "doi": "https://doi.org/10.1093/brain/awaa334", | |
| "journal": "Brain", | |
| "last_author": "Jonathan Mill", | |
| "model_type": "elastic net regression", | |
| "n_features": 347, | |
| "notes": "Cortex-specific DNA-methylation chronological-age estimator trained by elastic net on 1,047 post-mortem cortical samples; its 347-CpG weighted score is back-transformed to years.", | |
| "platform": [ | |
| "Illumina 450K" | |
| ], | |
| "population": "all ages", | |
| "postprocess": "anti_log_linear", | |
| "predicts": [ | |
| "chronological age" | |
| ], | |
| "reference_values": true, | |
| "research_only": null, | |
| "species": "Homo sapiens", | |
| "tissue": [ | |
| "brain cortex" | |
| ], | |
| "training_target": [ | |
| "chronological age" | |
| ], | |
| "unit": [ | |
| "years" | |
| ], | |
| "version": "0.5.7", | |
| "year": 2020 | |
| } |