dnamfili

Epigenetic frailty risk score (eFRS), a weighted 20-CpG whole-blood DNA-methylation score selected by LASSO from replicated frailty-associated loci.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts	frailty risk
Species	Homo sapiens
Tissue	whole blood
Data type	DNA methylation
Model type	LASSO regression
Year	2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["dnamfili"])

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Citation

Li, X. et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications 13, 5269 (2022).

https://doi.org/10.1038/s41467-022-32893-x