dnamstress

Whole-blood methylation score (MS stress) derived as a 211-CpG proxy for a composite of 13 stress-related measures.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts	stress exposure
Species	Homo sapiens
Tissue	whole blood
Data type	DNA methylation
Model type	bootstrap-stabilized elastic net regression
Year	2023

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["dnamstress"])

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Citation

Jung, J., et al. “Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder.” Biological Psychiatry 93(4): 331–341 (2023).

https://doi.org/10.1016/j.biopsych.2022.06.036