---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# garagnani

The source study identified age-associated ELOVL2 methylation, but did not publish a one-CpG age equation. Pyaging returns the raw cg16867657 methylation beta value using coefficient 1 and zero intercept; it does not return calibrated chronological age.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | ELOVL2 methylation |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | single-CpG score |
| **Year** | 2012 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["garagnani"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Garagnani, Paolo, et al. "Methylation of ELOVL2 gene as a new epigenetic marker of age." Aging Cell 11.6 (2012): 1132-1134.

https://doi.org/10.1111/acel.12005