---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# hannum

Whole-blood elastic-net predictor of chronological age from 71 CpG methylation fractions, derived in a 482-person primary cohort and validated in 174 independent participants.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | chronological age |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2013 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["hannum"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Hannum, G., et al. “Genome-wide methylation profiles reveal quantitative views of human aging rates.” Molecular Cell 49(2), 359–367 (2013).

https://doi.org/10.1016/j.molcel.2012.10.016