---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# mammalianlifespan

Pan-mammalian tissue-agnostic elastic-net predictor fitted to log species maximum life span from conserved CpG methylation; pyaging exponentiates the linear output to years.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | species maximum lifespan |
| **Species** | multiple species |
| **Tissue** | multi-tissue |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2024 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["mammalianlifespan"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Li, Caesar Z., et al. "Epigenetic predictors of species maximum life span and other life-history traits in mammals." Science Advances 10.23 (2024): eadm7273.

https://doi.org/10.1126/sciadv.adm7273