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README.md
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- genomics
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- single-cell
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- model_cls_name:CondSCVI
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- scvi_version:1.
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- anndata_version:0.
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- modality:rna
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- tissue:various
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- annotated:True
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CondSCVI takes as input a scRNA-seq gene expression matrix with cells and genes as well as a
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cell-type annotation for all cells.
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We provide an extensive [user guide](https://docs.scvi-tools.org/en/
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for DestVI including a description of CondSCVI.
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- See our original manuscript for further details of the model:
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**Cell-wise Coefficient of Variation**:
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|-------------------------|----------------|------------------|
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| Mean Absolute Error | 1.67 | 1.66 |
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| Pearson Correlation | 0.72 | 0.73 |
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| Spearman Correlation | 0.70 | 0.71 |
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| R² (R-Squared) | 0.40 | 0.38 |
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The gene-wise coefficient of variation summarizes how well variation between different genes is
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preserved by the generated model expression. This value is usually quite high.
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**Gene-wise Coefficient of Variation**:
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|-------------------------|----------------|
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| Mean Absolute Error | 29.93 |
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| Pearson Correlation | 0.63 |
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| Spearman Correlation | 0.60 |
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| R² (R-Squared) | -27.26 |
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</details>
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**Differential expression**:
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| --- | --- | --- | --- | --- | --- | --- | --- |
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| basal cell | 0.84 | 0.78 | 0.70 | 0.82 | 0.42 | 0.88 | 6281.00 |
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| keratinocyte | 0.86 | 1.64 | 0.50 | 0.87 | 0.28 | 0.91 | 3667.00 |
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| epithelial cell | 0.59 | 1.02 | 0.17 | 0.57 | 0.56 | 0.88 | 2114.00 |
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| leukocyte | 0.77 | 1.53 | 0.29 | 0.56 | 0.43 | 0.87 | 2109.00 |
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| fibroblast | 0.58 | 4.03 | 0.14 | 0.35 | 0.55 | 0.82 | 251.00 |
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| vein endothelial cell | 0.64 | 4.67 | 0.22 | 0.26 | 0.58 | 0.84 | 226.00 |
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| pericyte | 0.44 | 5.37 | 0.28 | 0.27 | 0.47 | 0.72 | 117.00 |
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| capillary endothelial cell | 0.65 | 6.21 | 0.29 | 0.29 | 0.52 | 0.77 | 101.00 |
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| tongue muscle cell | 0.37 | 7.61 | 0.32 | 0.19 | 0.44 | 0.70 | 60.00 |
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| endothelial cell of lymphatic vessel | 0.42 | 7.81 | 0.29 | 0.20 | 0.49 | 0.71 | 44.00 |
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| endothelial cell of artery | 0.47 | 7.59 | 0.33 | 0.24 | 0.51 | 0.75 | 40.00 |
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</details>
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Arguments passed to setup_anndata of the original model:
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```json
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{
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}
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```
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<summary><strong>Data Registry</strong></summary>
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Registry elements for AnnData manager:
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| Registry Key
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|--------------|---------------------------|
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- **Data is Minified**: False
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<details>
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<summary><strong>Summary Statistics</strong></summary>
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| Summary Stat Key
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|------------------|-------|
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</details>
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- genomics
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- single-cell
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- model_cls_name:CondSCVI
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- scvi_version:1.4.2
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- anndata_version:0.12.7
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- modality:rna
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- tissue:various
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- annotated:True
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CondSCVI takes as input a scRNA-seq gene expression matrix with cells and genes as well as a
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cell-type annotation for all cells.
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+
We provide an extensive [user guide](https://docs.scvi-tools.org/en/stable/user_guide/models/destvi.html)
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for DestVI including a description of CondSCVI.
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- See our original manuscript for further details of the model:
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**Cell-wise Coefficient of Variation**:
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The gene-wise coefficient of variation summarizes how well variation between different genes is
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preserved by the generated model expression. This value is usually quite high.
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**Gene-wise Coefficient of Variation**:
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</details>
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**Differential expression**:
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</details>
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Arguments passed to setup_anndata of the original model:
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```json
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{
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"batch_key": null,
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"labels_key": "cell_type",
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"fine_labels_key": null,
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"layer": "counts",
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"unlabeled_category": "unlabeled",
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"size_factor_key": null
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}
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```
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<summary><strong>Data Registry</strong></summary>
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Registry elements for AnnData manager:
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| Registry Key | scvi-tools Location |
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|--------------------------|--------------------------------------|
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| X | adata.layers['counts'] |
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| batch | adata.obs['_scvi_batch'] |
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| labels | adata.obs['_scvi_labels'] |
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- **Data is Minified**: False
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<details>
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<summary><strong>Summary Statistics</strong></summary>
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| Summary Stat Key | Value |
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|--------------------------|-------|
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| n_batch | 1 |
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| n_cells | 38754 |
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| n_labels | 23 |
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| n_vars | 3000 |
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</details>
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