data/table_catalog.json

{
  "total_tables": 235,
  "categories": [
    "Clinical & Phenomics",
    "Chromosome Architecture",
    "Gene Panels & Interactome",
    "Mosaicism Spectrum",
    "ACMG & In Silico Predictors",
    "Precision Oncology & Pharma",
    "Cytogenetics & Aneuploidy",
    "Sequencing & Flowcell QC",
    "Biophysical Kinetics",
    "Comparative Oncology Cohorts"
  ],
  "tables": [
    {
      "id": "clin_01_hpo_ontological_ic",
      "category": "Clinical & Phenomics",
      "title": "HPO Ontological Hierarchy & Information Content Scoring",
      "description": "Ontological ancestry paths and calculated Information Content (IC) for proband clinical manifestations.",
      "row_count": 8,
      "columns_count": 6,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_02_classical_triad_scoring",
      "category": "Clinical & Phenomics",
      "title": "Classical MVA Diagnostic Triad Multi-Subtype Scoring",
      "description": "Quantitative matching of patient findings against diagnostic hallmarks across MVA Subtypes 1 through 4.",
      "row_count": 5,
      "columns_count": 7,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_03_growth_fenton_trajectories",
      "category": "Clinical & Phenomics",
      "title": "Gestational & Postnatal Growth Percentile Trajectory Audit",
      "description": "Anthropometric Z-scores and growth percentile deviations mapped against Fenton 2013 Preterm standards.",
      "row_count": 5,
      "columns_count": 6,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_04_erms_histopathology",
      "category": "Clinical & Phenomics",
      "title": "Embryonal Rhabdomyosarcoma (ERMS) Histopathology & Molecular Markers",
      "description": "Histopathological examination, immunohistochemical profiling, and genetic fusion status of patient tumor.",
      "row_count": 6,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_05_nephrocalcinosis_ultrasound",
      "category": "Clinical & Phenomics",
      "title": "Congenital Medullary Nephrocalcinosis Staging & Renal Sonography",
      "description": "Renal ultrasound grading, parenchymal echogenicity, and corticomedullary differentiation metrics.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_06_calcium_phosphate_handling",
      "category": "Clinical & Phenomics",
      "title": "Renal Tubular Calcium & Phosphate Handling Biomarker Profile",
      "description": "Serum electrolytes, fractional excretion indices, and urinary tubular transport metrics in proband.",
      "row_count": 6,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_07_parental_recurrent_rpl",
      "category": "Clinical & Phenomics",
      "title": "Parental Recurrent Pregnancy Loss & Meiotic Nondisjunction History",
      "description": "Reproductive genetic history, parental karyotypes, and chromosomal meiotic segregation failure analysis.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_08_satellite_cell_atrophy",
      "category": "Clinical & Phenomics",
      "title": "Skeletal Muscle Satellite Cell Depletion & Muscle Caliber Profile",
      "description": "Myogenic stem cell proliferation capacity, muscle fiber caliber, and sarcomeric integrity in proband.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_09_microcephaly_neurodevelopment",
      "category": "Clinical & Phenomics",
      "title": "Congenital Microcephaly & Cortical Neurogenesis Vulnerability",
      "description": "Radial glial cell division kinetics, cerebral cortex thickness, and neurodevelopmental tracking.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_10_wilms_nephroblastomatosis",
      "category": "Clinical & Phenomics",
      "title": "Wilms Tumor vs Nephroblastomatosis Predisposition Index",
      "description": "Nephrogenic rest surveillance, WT1 locus variant screening, and renal neoplasia risk stratification.",
      "row_count": 3,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_11_leukemogenesis_mds_risk",
      "category": "Clinical & Phenomics",
      "title": "Hematopoietic Clonal Instability & Bone Marrow Surveillance",
      "description": "Peripheral blood smear cytogenetics, cytopenias, and clonal hematopoiesis surveillance metrics.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_12_pan_cancer_surveillance",
      "category": "Clinical & Phenomics",
      "title": "Comprehensive Pediatric Pan-Cancer Surveillance Schedule",
      "description": "Evidence-based screening modalities, target organ systems, and surveillance frequency recommendations.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_13_confined_placental_mosaicism",
      "category": "Clinical & Phenomics",
      "title": "Confined Placental Mosaicism (CPM) vs Embryonic Aneuploidy Discrimination",
      "description": "Chorionic villus sampling vs amniocyte discordance models in prenatal growth restriction.",
      "row_count": 3,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_14_gh_igf1_endocrine_axis",
      "category": "Clinical & Phenomics",
      "title": "Hypothalamic-Pituitary-IGF1 Growth Axis Evaluation in MVA",
      "description": "Endocrine hormone levels, growth hormone responsiveness, and cellular growth resistance indices.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_15_craniofacial_metrics",
      "category": "Clinical & Phenomics",
      "title": "Craniofacial Dysmorphic Measurements & Anthropometric Facial Indices",
      "description": "Facial landmark dimensions, canthal distances, and palpebral fissure measurements.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_16_ophthalmic_cataracts_screen",
      "category": "Clinical & Phenomics",
      "title": "Ophthalmic & Retinal Aneuploidy Manifestation Screen",
      "description": "Slit-lamp examination, corneal diameter, fundoscopy, and visual evoked potential findings.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_17_cardiovascular_echocardiogram",
      "category": "Clinical & Phenomics",
      "title": "Congenital Cardiovascular Screening & Echocardiography Matrix",
      "description": "Doppler echocardiography, great vessel branching, and valvular structural evaluation in proband.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_18_lymphocyte_senescence",
      "category": "Clinical & Phenomics",
      "title": "Immune System T/B Cell Senescence & Lymphocyte Kinetics",
      "description": "Flow cytometry lymphocyte subsets, immunoglobulin levels, and cellular senescence markers in MVA.",
      "row_count": 6,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_19_dermatoglyphics_palmar_crease",
      "category": "Clinical & Phenomics",
      "title": "Dermatoglyphic Patterns & Minor Physical Aneuploidy Anomaly Audit",
      "description": "Palmar crease patterns, fingertip ridge configurations, and axial triradius positions.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_20_hepatic_function_matrix",
      "category": "Clinical & Phenomics",
      "title": "Hepatic Parenchymal Function & Microvesicular Stability Matrix",
      "description": "Liver enzymes, synthetic coagulopathy markers, and ultrasound parenchymal assessment in MVA.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_21_gastrointestinal_motility",
      "category": "Clinical & Phenomics",
      "title": "Gastrointestinal Autonomic Innervation & Motility Biomarkers",
      "description": "Enteric neuronal migration, abdominal radiograph findings, and caloric absorption kinetics.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_22_adrenal_stress_cortisol",
      "category": "Clinical & Phenomics",
      "title": "Adrenocortical Function & Stress Response Biomarker Profile",
      "description": "Basal cortisol, ACTH stimulation, and mineralocorticoid steroidogenesis in proband.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_23_radiosensitivity_guidelines",
      "category": "Clinical & Phenomics",
      "title": "Constitutional Radiosensitivity & Diagnostic Genotoxic Precautions",
      "description": "Radiation exposure safety thresholds, chromosomal break induction, and imaging guidelines for MVA.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_24_familial_recurrence_counseling",
      "category": "Clinical & Phenomics",
      "title": "Autosomal Recessive vs De Novo Germline Mosaicism Recurrence Risk",
      "description": "Mendelian inheritance models, parental carrier status, and recurrence risk for future pregnancies.",
      "row_count": 4,
      "columns_count": 5,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "clin_25_bayesian_differential_model",
      "category": "Clinical & Phenomics",
      "title": "Multi-Feature Bayesian Diagnostic Posterior Probability Model",
      "description": "Bayesian posterior likelihood cross-matching for 12 rare syndromes presenting with growth restriction and tumors.",
      "row_count": 8,
      "columns_count": 6,
      "tags": [
        "Clinical",
        "Phenomics"
      ]
    },
    {
      "id": "chr_chr1_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR1 Fine-Grained Architecture & Locus Dynamics",
      "description": "Largest autosome; contains CENPF corona kinesin-adapter and 1p36 subtelomeric fragile region. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR1.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr1",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr2_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR2 Fine-Grained Architecture & Locus Dynamics",
      "description": "Harbors BUB1 kinetochore kinase and ancient 2q13 hominid fusion telomeric junction. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR2.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr2",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr3_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR3 Fine-Grained Architecture & Locus Dynamics",
      "description": "Harbors FRA3B common fragile site; high sensitivity to aphidicolin replication stress. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR3.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr3",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr4_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR4 Fine-Grained Architecture & Locus Dynamics",
      "description": "Key checkpoint chromosome; encodes MAD2L1 spindle clamp and CENPE plus-end motor. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR4.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr4",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr5_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR5 Fine-Grained Architecture & Locus Dynamics",
      "description": "Critical MVA3 locus; harbors TRIP13 AAA+ ATPase disassembler and 5p telomerase core. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR5.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr5",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr6_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR6 Fine-Grained Architecture & Locus Dynamics",
      "description": "MHC immunological cluster and FRA6E fragile site; high somatic copy-number stability. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR6.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr6",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr7_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR7 Fine-Grained Architecture & Locus Dynamics",
      "description": "Encodes MAD1L1 kinetochore anchor dimer; frequent aneuploid missegregation in MVA. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR7.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr7",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr8_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR8 Fine-Grained Architecture & Locus Dynamics",
      "description": "High constitutional trisomy 8 variegation in MVA lymphocytes; MYC oncogene hub. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR8.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr8",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr9_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR9 Fine-Grained Architecture & Locus Dynamics",
      "description": "Encodes SMC5 chromosome decatenation subunit and 9q12 Satellite III pericentric heterochromatin. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR9.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr9",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr10_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR10 Fine-Grained Architecture & Locus Dynamics",
      "description": "Encodes BUB3 WD40 propeller scaffold and ZWINT KNL1-docking structural component. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR10.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr10",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr11_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR11 Fine-Grained Architecture & Locus Dynamics",
      "description": "Critical MVA2 locus; encodes CEP57 centriolar anchor and 11p15.5 imprinting cluster. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR11.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr11",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr12_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR12 Fine-Grained Architecture & Locus Dynamics",
      "description": "12q14 amplicon hub; harbors KRAS signaling and CDK4/MDM2 cell cycle machinery. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR12.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr12",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr13_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR13 Fine-Grained Architecture & Locus Dynamics",
      "description": "Acrocentric autosome with NOR rDNA arrays; harbors RB1 tumor suppressor and FOXO1 RMS locus. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR13.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr13",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr14_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR14 Fine-Grained Architecture & Locus Dynamics",
      "description": "Encodes DICER1 microRNA processing endoribonuclease and immunoglobulin heavy chain locus. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR14.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr14",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr15_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR15 Fine-Grained Architecture & Locus Dynamics",
      "description": "Primary MVA1 master locus; encodes BUB1B/BUBR1 spindle assembly checkpoint kinase. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR15.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr15",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr16_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR16 Fine-Grained Architecture & Locus Dynamics",
      "description": "Encodes PLK1 Polo-like master mitotic kinase and 16q23.2 FRA16D fragile region. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR16.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr16",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr17_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR17 Fine-Grained Architecture & Locus Dynamics",
      "description": "Harbors TP53 guardian of the genome; frequent 17p LOH in rhabdomyosarcoma progression. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR17.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr17",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr18_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR18 Fine-Grained Architecture & Locus Dynamics",
      "description": "Critical MVA4 locus; encodes CEP192 pericentriolar PCM scaffold and Aurora A recruiter. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR18.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr18",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr19_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR19 Fine-Grained Architecture & Locus Dynamics",
      "description": "Highest gene and variant density in human genome (1,922 / Mb); GC-rich isochore core. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR19.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr19",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr20_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR20 Fine-Grained Architecture & Locus Dynamics",
      "description": "Encodes AURKA Aurora Kinase A; centrosome maturation and spindle bipolarity hub. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR20.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr20",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr21_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR21 Fine-Grained Architecture & Locus Dynamics",
      "description": "Smallest acrocentric autosome; Down syndrome critical region and Robertsonian partner. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR21.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr21",
        "Genomics"
      ]
    },
    {
      "id": "chr_chr22_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHR22 Fine-Grained Architecture & Locus Dynamics",
      "description": "Acrocentric chromosome; encodes CHEK2 checkpoint kinase and BCR-ABL translocation site. Analysis of variant density, SNV/Indel balance, and candidate loci on CHR22.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chr22",
        "Genomics"
      ]
    },
    {
      "id": "chr_chrX_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHRX Fine-Grained Architecture & Locus Dynamics",
      "description": "Sex chromosome; subject to X-inactivation; frequent variegated loss in MVA lymphocytes. Analysis of variant density, SNV/Indel balance, and candidate loci on CHRX.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chrX",
        "Genomics"
      ]
    },
    {
      "id": "chr_chrY_structural_architecture",
      "category": "Chromosome Architecture",
      "title": "Chromosome CHRY Fine-Grained Architecture & Locus Dynamics",
      "description": "Heterochromatic male sex chromosome; high somatic loss-of-Y (LOY) rate in aneuploid clones. Analysis of variant density, SNV/Indel balance, and candidate loci on CHRY.",
      "row_count": 5,
      "columns_count": 5,
      "tags": [
        "Chromosome",
        "chrY",
        "Genomics"
      ]
    },
    {
      "id": "chr_cin70_burden_scores",
      "category": "Chromosome Architecture",
      "title": "CIN70 Chromosomal Instability Mutational Signature Scoring",
      "description": "Mutational burden, VAF values, and GATK quality metrics across the classic 70-gene CIN70 signature.",
      "row_count": 9,
      "columns_count": 6,
      "tags": [
        "CIN70",
        "Chromosomal Instability",
        "Signatures"
      ]
    },
    {
      "id": "chr_cosmic_sbs_profiles",
      "category": "Chromosome Architecture",
      "title": "COSMIC Single Base Substitution (SBS) Mutational Signatures in MVA",
      "description": "Decomposition of patient whole-genome SNV callset into standard COSMIC v3.3 trinucleotide mutational signatures.",
      "row_count": 5,
      "columns_count": 6,
      "tags": [
        "COSMIC",
        "Mutational Signatures",
        "Trinucleotide"
      ]
    },
    {
      "id": "chr_cn_loh_recombination_map",
      "category": "Chromosome Architecture",
      "title": "Segmental Copy-Neutral Loss-of-Heterozygosity (CN-LOH) Loci",
      "description": "Contiguous homozygous variant stretches identifying mitotic recombination and uniparental disomy intervals.",
      "row_count": 5,
      "columns_count": 6,
      "tags": [
        "LOH",
        "Mitotic Recombination",
        "Copy Neutral"
      ]
    },
    {
      "id": "chr_pericentromeric_satellite_fragility",
      "category": "Chromosome Architecture",
      "title": "Pericentromeric Heterochromatin Satellite Repeat Fragility Audit",
      "description": "Satellite II/III repeat stability, classical centromere constriction, and pericentromeric variant clustering.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Heterochromatin",
        "Pericentromere",
        "Satellite Repeats"
      ]
    },
    {
      "id": "chr_subtelomeric_recomb_caps",
      "category": "Chromosome Architecture",
      "title": "Subtelomeric Recombination Hotspots & Terminal Cap Integrity",
      "description": "Terminal 2Mb repeat content, telomeric variant density, and subtelomeric rearrangement hotspots.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Subtelomeres",
        "Recombination",
        "Caps"
      ]
    },
    {
      "id": "chr_cfs_breakage_indices",
      "category": "Chromosome Architecture",
      "title": "Common Fragile Sites (CFS) Breakage Susceptibility Index",
      "description": "Genomic coordinates of aphidicolin-sensitive common fragile sites and structural break vulnerability in MVA.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Fragile Sites",
        "Replication Stress",
        "Breaks"
      ]
    },
    {
      "id": "mit_bub1b_pseudokinase_clamp",
      "category": "Gene Panels & Interactome",
      "title": "BUB1B / BUBR1 Pseudokinase Domain & CDC20 Clamping Kinetics",
      "description": "BUBR1 TPR motifs, KARD phospho-domain, and CDC20 binding clamp.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "BUB1B"
      ]
    },
    {
      "id": "mit_cep57_centriole_inner_barrel",
      "category": "Gene Panels & Interactome",
      "title": "CEP57 Centriolar Inner Barrel Attachment & Tubulin Nucleation",
      "description": "CEP57 coiled-coil inner wall anchoring and MVA2 nephrocalcinosis.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CEP57"
      ]
    },
    {
      "id": "mit_trip13_aaa_atpase_hexamer",
      "category": "Gene Panels & Interactome",
      "title": "TRIP13 AAA+ ATPase Hexameric Disassembly Engine",
      "description": "ATP-dependent unfolding of C-MAD2 and mosaic somatic driver mechanics.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "TRIP13"
      ]
    },
    {
      "id": "mit_cep192_pcm_aurora_recruitment",
      "category": "Gene Panels & Interactome",
      "title": "CEP192 Pericentriolar Matrix Scaffold & Kinase Co-Recruitment",
      "description": "Centrosomal recruitment of AURKA and PLK1 in spindle bipolarity.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CEP192"
      ]
    },
    {
      "id": "mit_mad1l1_kinetochore_docking",
      "category": "Gene Panels & Interactome",
      "title": "MAD1L1 Coiled-Coil Dimerization & Kinetochore Corona Anchor",
      "description": "MAD1-MAD2 catalytic template and corona expansion.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "MAD1L1"
      ]
    },
    {
      "id": "mit_mad2l1_topological_safety_belt",
      "category": "Gene Panels & Interactome",
      "title": "MAD2L1 Topological Clamp & CDC20 Entrapment Dynamics",
      "description": "Open-to-closed conformer transition and APC/C inhibition.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "MAD2L1"
      ]
    },
    {
      "id": "mit_bub1_melt_phospho_cascade",
      "category": "Gene Panels & Interactome",
      "title": "BUB1 Kinase & KNL1 MELT Phosphorylation Hierarchy",
      "description": "Multi-site phosphorylation of KNL1 coordinating outer kinetochore assembly.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "BUB1"
      ]
    },
    {
      "id": "mit_bub3_wd40_beta_propeller",
      "category": "Gene Panels & Interactome",
      "title": "BUB3 7-Bladed WD40 \u03b2-Propeller & Phospho-MELT Reader",
      "description": "Structural recognition of phosphorylated MELT motifs on KNL1.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "BUB3"
      ]
    },
    {
      "id": "mit_cenpe_kinesin7_translocation",
      "category": "Gene Panels & Interactome",
      "title": "CENPE Kinesin-7 Motor Mechanics & Chromosome Congression",
      "description": "Single-molecule stepping kinetics and metaphase alignment.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CENPE"
      ]
    },
    {
      "id": "mit_cenpf_corona_farnesylation",
      "category": "Gene Panels & Interactome",
      "title": "CENPF C-Terminal Farnesylation & Dynein Cargo Coupling",
      "description": "Outer corona structural expansion and Dynein-Dynactin recruitment.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CENPF"
      ]
    },
    {
      "id": "mit_aurka_tpx2_spindle_bipolarity",
      "category": "Gene Panels & Interactome",
      "title": "Aurora Kinase A - TPX2 Allosteric Spindle Pole Organizer",
      "description": "Centrosome maturation, spindle pole separation, and bipolarity.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "AURKA"
      ]
    },
    {
      "id": "mit_plk1_polo_box_substrate_docking",
      "category": "Gene Panels & Interactome",
      "title": "PLK1 Polo-Box Domain Phosphopeptide Recognition",
      "description": "Polo-box phosphopeptide docking and mitotic entry orchestration.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "PLK1"
      ]
    },
    {
      "id": "mit_smc5_smc6_cohesin_decatenation",
      "category": "Gene Panels & Interactome",
      "title": "SMC5/6 Complex & Post-Replicative Decatenation Checkpoint",
      "description": "Topoisomerase II assistance and chromosome arm resolution.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "SMC5"
      ]
    },
    {
      "id": "mit_rad21_stag2_sister_cohesion",
      "category": "Gene Panels & Interactome",
      "title": "RAD21 / STAG2 Cohesin Ring Structure & Separase Cleavage",
      "description": "Centromeric sister chromatid cohesion and anaphase trigger.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "RAD21"
      ]
    },
    {
      "id": "mit_sgo1_shugoshin_pp2a_protection",
      "category": "Gene Panels & Interactome",
      "title": "SGO1 (Shugoshin) / PP2A Centromeric Cohesion Protector",
      "description": "Protection of centromeric cohesin against prophase removal pathway.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "SGO1"
      ]
    },
    {
      "id": "mit_haspin_histone_h3t3_cpc_docking",
      "category": "Gene Panels & Interactome",
      "title": "Haspin Kinase Phosphorylation of H3T3 & CPC Kinetochore Docking",
      "description": "Centromeric targeting of the Chromosomal Passenger Complex (CPC).",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "HASPIN"
      ]
    },
    {
      "id": "mit_aurkb_borealin_survivin_incenp",
      "category": "Gene Panels & Interactome",
      "title": "Aurora B Chromosomal Passenger Complex (CPC) Tension Sensing",
      "description": "Phosphorylation of Ndc80 tail and error correction of syntelic attachments.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "AURKB"
      ]
    },
    {
      "id": "mit_mps1_ttk_activation_loop",
      "category": "Gene Panels & Interactome",
      "title": "MPS1 / TTK Kinase Autophosphorylation & Checkpoint Initiation",
      "description": "Kinetochore recruitment and MELT phosphorylation initiation.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "MPS1"
      ]
    },
    {
      "id": "mit_zw10_rod_zwilch_rzz_complex",
      "category": "Gene Panels & Interactome",
      "title": "RZZ Complex (ROD-ZW10-Zwilch) & Kinetochore Corona Assembly",
      "description": "Outer corona expansion and Spindly-Dynein adapter docking.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "ZW10"
      ]
    },
    {
      "id": "mit_spindly_dynein_sac_stripping",
      "category": "Gene Panels & Interactome",
      "title": "Spindly Adapter & Dynein-Mediated Checkpoint Protein Stripping",
      "description": "Mechanical transport of MAD2/BUBR1 along microtubules to centrosomes.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "SPINDLY"
      ]
    },
    {
      "id": "mit_apc_c_cdc20_cdh1_degron_selection",
      "category": "Gene Panels & Interactome",
      "title": "APC/C E3 Ubiquitin Ligase D-Box & KEN-Box Degron Selection",
      "description": "Ubiquitination of Securin and Cyclin B1 for anaphase onset.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "APC"
      ]
    },
    {
      "id": "mit_securin_pttgl1_separase_inhibitor",
      "category": "Gene Panels & Interactome",
      "title": "Securin (PTTG1) Degradation & Separase Protease Activation",
      "description": "Release of active Separase to cleave RAD21 cohesin rings.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "SECURIN"
      ]
    },
    {
      "id": "mit_cyclin_b1_ccnb1_cdk1_clearance",
      "category": "Gene Panels & Interactome",
      "title": "Cyclin B1 / CDK1 Kinase Clearance Dynamics at Metaphase Exit",
      "description": "Dephosphorylation cascade driving mitotic spindle disassembly.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CYCLIN"
      ]
    },
    {
      "id": "mit_p31comet_mad2l1bp_trip13_dock",
      "category": "Gene Panels & Interactome",
      "title": "p31(comet) Adapter Docking to Closed-MAD2 for TRIP13 Unfolding",
      "description": "Structural adapter driving SAC silencing and checkpoint inactivation.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "P31COMET"
      ]
    },
    {
      "id": "mit_ndc80_hec1_microtubule_coupling",
      "category": "Gene Panels & Interactome",
      "title": "Ndc80 (Hec1) Microtubule Coupling & Tension Elasticity",
      "description": "Calponin homology domain binding to tubulin protofilaments.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "NDC80"
      ]
    },
    {
      "id": "mit_knl1_casc5_melt_array_scaffold",
      "category": "Gene Panels & Interactome",
      "title": "KNL1 (CASC5) Multiple MELT Repeat Structural Scaffold",
      "description": "Intrinsically disordered docking platform for BUB3-BUBR1 complexes.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "KNL1"
      ]
    },
    {
      "id": "mit_mis12_dsn1_nsl1_pmf1_linker",
      "category": "Gene Panels & Interactome",
      "title": "Mis12 Complex Molecular Linker Between CENP-C and Ndc80",
      "description": "Four-subunit bridging complex connecting inner centromere to outer plate.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "MIS12"
      ]
    },
    {
      "id": "mit_cenpa_histone_h3_variant_nucleosome",
      "category": "Gene Panels & Interactome",
      "title": "CENP-A Centromeric Histone H3 Variant & Epigenetic Centromere",
      "description": "Epigenetic specification of kinetochore assembly loci on satellite DNA.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CENPA"
      ]
    },
    {
      "id": "mit_cenpc_inner_kinetochore_cup",
      "category": "Gene Panels & Interactome",
      "title": "CENP-C Central Kinetochore Hub & Mis12-CENPA Bridging",
      "description": "Direct interaction bridging CENP-A nucleosomes to outer Mis12 complex.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CENPC"
      ]
    },
    {
      "id": "mit_cenpt_inner_kinetochore_pathway",
      "category": "Gene Panels & Interactome",
      "title": "CENP-T Centromeric DNA-Binding & Direct Ndc80 Recruitment",
      "description": "Alternative non-Mis12 pathway for outer kinetochore microtubule tethering.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CENPT"
      ]
    },
    {
      "id": "mit_kif2c_mcak_microtubule_depolymerase",
      "category": "Gene Panels & Interactome",
      "title": "KIF2C (MCAK) Kinetochore Microtubule Depolymerase",
      "description": "Error correction of merotelic and syntelic microtubule-kinetochore attachments.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "KIF2C"
      ]
    },
    {
      "id": "mit_clasp1_clasp2_microtubule_plus_end",
      "category": "Gene Panels & Interactome",
      "title": "CLASP1 / CLASP2 Kinetochore Plus-End Microtubule Rescuers",
      "description": "Promotion of microtubule rescue and stabilization under tension.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CLASP1"
      ]
    },
    {
      "id": "mit_kif18a_kinesin8_length_dependent_motor",
      "category": "Gene Panels & Interactome",
      "title": "KIF18A Kinesin-8 Length-Dependent Microtubule Depolymerase",
      "description": "Dampening of chromosome oscillations and metaphase alignment confinement.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "KIF18A"
      ]
    },
    {
      "id": "mit_chmp4b_escrt_iii_micronucleus_repair",
      "category": "Gene Panels & Interactome",
      "title": "ESCRT-III (CHMP4B) Micronuclear Envelope Repair Complex",
      "description": "Sealing of ruptured micronuclear envelopes to prevent DNA damage.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "CHMP4B"
      ]
    },
    {
      "id": "mit_trex1_micronuclear_dna_exonuclease",
      "category": "Gene Panels & Interactome",
      "title": "TREX1 Endoplasmic Reticulum DNA Exonuclease & cGAS Degradation",
      "description": "Cleavage of shattered micronuclear DNA fragments upon envelope collapse.",
      "row_count": 3,
      "columns_count": 6,
      "tags": [
        "Gene Panel",
        "Mitotic Checkpoint",
        "TREX1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_01",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 01: TRIP13 c.1060G>A (27.8% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for TRIP13 c.1060G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "TRIP13"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_02",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 02: BUB1B c.1972C>T (51.4% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for BUB1B c.1972C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "BUB1B"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_03",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 03: CEP57 c.403C>T (51.4% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for CEP57 c.403C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "CEP57"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_04",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 04: MAD1L1 c.1852C>T (22.2% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for MAD1L1 c.1852C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "MAD1L1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_05",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 05: CEP192 c.1504G>A (18.5% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for CEP192 c.1504G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "CEP192"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_06",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 06: TP53 c.524G>A (34.2% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for TP53 c.524G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "TP53"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_07",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 07: WT1 c.1180C>T (14.8% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for WT1 c.1180C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "WT1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_08",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 08: DICER1 c.5438A>G (11.2% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for DICER1 c.5438A>G.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "DICER1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_09",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 09: CENPE c.7123G>A (48.9% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for CENPE c.7123G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "CENPE"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_10",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 10: CENPF c.5461C>T (16.4% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for CENPF c.5461C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "CENPF"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_11",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 11: PLK1 c.628G>A (9.5% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for PLK1 c.628G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "PLK1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_12",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 12: AURKA c.883A>G (100.0% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for AURKA c.883A>G.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "AURKA"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_13",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 13: SMC5 c.1441G>A (8.2% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for SMC5 c.1441G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "SMC5"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_14",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 14: RAD21 c.1105C>T (6.4% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for RAD21 c.1105C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "RAD21"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_15",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 15: SGO1 c.892A>G (5.1% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for SGO1 c.892A>G.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "SGO1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_16",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 16: MPS1 c.2026A>T (4.3% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for MPS1 c.2026A>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "MPS1"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_17",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 17: ZWINT c.421G>A (3.8% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for ZWINT c.421G>A.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "ZWINT"
      ]
    },
    {
      "id": "mos_strata_vaf_bin_18",
      "category": "Mosaicism Spectrum",
      "title": "Mosaicism Stratum 18: KIF2C c.1684C>T (42.1% VAF) Lineage Profile",
      "description": "Allelic fraction quantification, sequencing read support, and lineage allocation for KIF2C c.1684C>T.",
      "row_count": 4,
      "columns_count": 7,
      "tags": [
        "Mosaicism",
        "VAF",
        "KIF2C"
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        "VEST4"
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        "MetaSVM"
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        "MetaLR"
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        "BayesDel"
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        "LRT"
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        "ACMG",
        "InSilico",
        "DANN"
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        "Eigen-PC"
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        "GenoCanyon"
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        "Volasertib"
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        "Oncology",
        "Talazoparib"
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        "Olaparib"
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        "Dactinomycin"
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        "Hydroxychloroquine"
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        "Pembrolizumab"
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        "Selinexor"
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      "id": "pharm_oncology_profile_23",
      "category": "Precision Oncology & Pharma",
      "title": "Precision Oncology Stratum 23: Vorinostat (SAHA) Pharmacology & Synergy",
      "description": "Cellular IC50 potency, synthetic lethality mechanism, and safety considerations for Vorinostat (SAHA).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Pharmacology",
        "Oncology",
        "Vorinostat"
      ]
    },
    {
      "id": "pharm_oncology_profile_24",
      "category": "Precision Oncology & Pharma",
      "title": "Precision Oncology Stratum 24: JQ1 BET Inhibitor Pharmacology & Synergy",
      "description": "Cellular IC50 potency, synthetic lethality mechanism, and safety considerations for JQ1 BET Inhibitor.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Pharmacology",
        "Oncology",
        "JQ1"
      ]
    },
    {
      "id": "pharm_oncology_profile_25",
      "category": "Precision Oncology & Pharma",
      "title": "Precision Oncology Stratum 25: ARV-110 PROTAC Pharmacology & Synergy",
      "description": "Cellular IC50 potency, synthetic lethality mechanism, and safety considerations for ARV-110 PROTAC.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Pharmacology",
        "Oncology",
        "ARV-110"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_01",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 01: Premature Centromere Division (PCD) Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Premature Centromere Division (PCD).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Premature"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_02",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 02: Chromosome Missegregation Rate Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Chromosome Missegregation Rate.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Chromosome"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_03",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 03: Micronucleus Frequency Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Micronucleus Frequency.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Micronucleus"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_04",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 04: Multipolar Spindle Frequency Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Multipolar Spindle Frequency.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Multipolar"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_05",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 05: Sister Chromatid Exchange (SCE) Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Sister Chromatid Exchange (SCE).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Sister"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_06",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 06: Tetraploid Endoreduplication Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Tetraploid Endoreduplication.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Tetraploid"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_07",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 07: Acrocentric Satellite Association Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Acrocentric Satellite Association.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Acrocentric"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_08",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 08: Sex Chromosome Variegation Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Sex Chromosome Variegation.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Sex"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_09",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 09: Fragile Site Gaps (Aphidicolin) Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Fragile Site Gaps (Aphidicolin).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Fragile"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_10",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 10: Centromeric Cohesion Loss Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Centromeric Cohesion Loss.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Centromeric"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_11",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 11: Radial Nuclear Organization Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Radial Nuclear Organization.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Radial"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_12",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 12: Mitotic Index (MI%) Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Mitotic Index (MI%).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Mitotic"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_13",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 13: Telomere PNA-FISH Variance Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Telomere PNA-FISH Variance.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Telomere"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_14",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 14: Alpha-Satellite Repeat Arrays Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Alpha-Satellite Repeat Arrays.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Alpha-Satellite"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_15",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 15: TREX1 Ruptured Micronuclei Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for TREX1 Ruptured Micronuclei.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "TREX1"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_16",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 16: Death-in-Mitosis vs Slippage Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Death-in-Mitosis vs Slippage.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Death-in-Mitosis"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_17",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 17: Phylogenetic Karyotype Subtrees Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Phylogenetic Karyotype Subtrees.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Phylogenetic"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_18",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 18: KIFC1 Clustering Capacity Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for KIFC1 Clustering Capacity.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "KIFC1"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_19",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 19: Chromothripsis Reintegration Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Chromothripsis Reintegration.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Chromothripsis"
      ]
    },
    {
      "id": "cyto_karyotype_phenotype_20",
      "category": "Cytogenetics & Aneuploidy",
      "title": "Cytogenetic Assay 20: Dicentric Bridge-Fusion Cycles Quantification",
      "description": "Quantitative cytogenetic parameters, metaphase counts, and clinical correlations for Dicentric Bridge-Fusion Cycles.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Cytogenetics",
        "Karyotype",
        "Dicentric"
      ]
    },
    {
      "id": "qc_telemetry_matrix_01",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 01: Lane L001 Microfluidics",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Lane L001 Microfluidics.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Lane"
      ]
    },
    {
      "id": "qc_telemetry_matrix_02",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 02: Lane L002 Dual-Laser Optics",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Lane L002 Dual-Laser Optics.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Lane"
      ]
    },
    {
      "id": "qc_telemetry_matrix_03",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 03: Lane L003 Thermal Peltier",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Lane L003 Thermal Peltier.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Lane"
      ]
    },
    {
      "id": "qc_telemetry_matrix_04",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 04: Lane L004 TDI Sensor Imaging",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Lane L004 TDI Sensor Imaging.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Lane"
      ]
    },
    {
      "id": "qc_telemetry_matrix_05",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 05: Forward Read 1 Quality",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Forward Read 1 Quality.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Forward"
      ]
    },
    {
      "id": "qc_telemetry_matrix_06",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 06: Reverse Read 2 Phasing",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Reverse Read 2 Phasing.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Reverse"
      ]
    },
    {
      "id": "qc_telemetry_matrix_07",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 07: TruSeq Adapter Trimming",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for TruSeq Adapter Trimming.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "TruSeq"
      ]
    },
    {
      "id": "qc_telemetry_matrix_08",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 08: Library Duplication Rate",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Library Duplication Rate.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Library"
      ]
    },
    {
      "id": "qc_telemetry_matrix_09",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 09: Insert Size Distribution",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Insert Size Distribution.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Insert"
      ]
    },
    {
      "id": "qc_telemetry_matrix_10",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 10: BWA-MEM GRCh38 Alignment",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for BWA-MEM GRCh38 Alignment.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "BWA-MEM"
      ]
    },
    {
      "id": "qc_telemetry_matrix_11",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 11: GATK BQSR Recalibration",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for GATK BQSR Recalibration.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "GATK"
      ]
    },
    {
      "id": "qc_telemetry_matrix_12",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 12: Exonic Coverage Uniformity",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Exonic Coverage Uniformity.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Exonic"
      ]
    },
    {
      "id": "qc_telemetry_matrix_13",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 13: GC Bias Coverage Curve",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for GC Bias Coverage Curve.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "GC"
      ]
    },
    {
      "id": "qc_telemetry_matrix_14",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 14: Mismatch Noise Floor",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Mismatch Noise Floor.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Mismatch"
      ]
    },
    {
      "id": "qc_telemetry_matrix_15",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 15: Indel Size Distribution",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Indel Size Distribution.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Indel"
      ]
    },
    {
      "id": "qc_telemetry_matrix_16",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 16: Ti/Tv Mutation Ratio",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Ti/Tv Mutation Ratio.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Ti/Tv"
      ]
    },
    {
      "id": "qc_telemetry_matrix_17",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 17: dbSNP 156 Concordance",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for dbSNP 156 Concordance.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "dbSNP"
      ]
    },
    {
      "id": "qc_telemetry_matrix_18",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 18: Chimeric Split-Reads",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Chimeric Split-Reads.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Chimeric"
      ]
    },
    {
      "id": "qc_telemetry_matrix_19",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 19: Soft-Clipped Read Clusters",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Soft-Clipped Read Clusters.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Soft-Clipped"
      ]
    },
    {
      "id": "qc_telemetry_matrix_20",
      "category": "Sequencing & Flowcell QC",
      "title": "Flowcell Telemetry 20: Flowcell Master COA",
      "description": "Detailed sequencing quality metrics, physical telemetry, and compliance benchmarks for Flowcell Master COA.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Sequencing QC",
        "NovaSeq",
        "Flowcell"
      ]
    },
    {
      "id": "bio_kinetics_matrix_01",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 01: TRIP13 AAA+ Hexamer Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for TRIP13 AAA+ Hexamer.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "TRIP13"
      ]
    },
    {
      "id": "bio_kinetics_matrix_02",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 02: CENPE Kinesin-7 Motor Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for CENPE Kinesin-7 Motor.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "CENPE"
      ]
    },
    {
      "id": "bio_kinetics_matrix_03",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 03: MAD1-MAD2 Dimerization Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for MAD1-MAD2 Dimerization.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "MAD1-MAD2"
      ]
    },
    {
      "id": "bio_kinetics_matrix_04",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 04: Aurora A - TPX2 Complex Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Aurora A - TPX2 Complex.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Aurora"
      ]
    },
    {
      "id": "bio_kinetics_matrix_05",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 05: PLK1 Polo-Box Domain Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for PLK1 Polo-Box Domain.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "PLK1"
      ]
    },
    {
      "id": "bio_kinetics_matrix_06",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 06: BUBR1-CDC20 Complex Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for BUBR1-CDC20 Complex.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "BUBR1-CDC20"
      ]
    },
    {
      "id": "bio_kinetics_matrix_07",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 07: KNL1 Multi-MELT Array Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for KNL1 Multi-MELT Array.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "KNL1"
      ]
    },
    {
      "id": "bio_kinetics_matrix_08",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 08: Ndc80 Complex Tail Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Ndc80 Complex Tail.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Ndc80"
      ]
    },
    {
      "id": "bio_kinetics_matrix_09",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 09: Spindle Microtubules Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Spindle Microtubules.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Spindle"
      ]
    },
    {
      "id": "bio_kinetics_matrix_10",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 10: Separase Protease Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Separase Protease.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Separase"
      ]
    },
    {
      "id": "bio_kinetics_matrix_11",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 11: Centrosomal PCM (CEP192) Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Centrosomal PCM (CEP192).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Centrosomal"
      ]
    },
    {
      "id": "bio_kinetics_matrix_12",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 12: Chromatin Elastic Fiber Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Chromatin Elastic Fiber.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Chromatin"
      ]
    },
    {
      "id": "bio_kinetics_matrix_13",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 13: Centriolar Transition Zone Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Centriolar Transition Zone.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Centriolar"
      ]
    },
    {
      "id": "bio_kinetics_matrix_14",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 14: cGAS Micronuclear Condensation Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for cGAS Micronuclear Condensation.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "cGAS"
      ]
    },
    {
      "id": "bio_kinetics_matrix_15",
      "category": "Biophysical Kinetics",
      "title": "Biophysical Parameter 15: Cellular ATP Consumption Mechanics",
      "description": "Nanomechanical measurements, thermodynamic free energies, and cellular kinetics for Cellular ATP Consumption.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Biophysics",
        "Kinetics",
        "Cellular"
      ]
    },
    {
      "id": "coh_registry_crossmatch_01",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 01: St. Jude Children's Research Hospital",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from St. Jude Children's Research Hospital.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "St."
      ]
    },
    {
      "id": "coh_registry_crossmatch_02",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 02: NCI TARGET Pan-Cancer Project",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from NCI TARGET Pan-Cancer Project.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "NCI"
      ]
    },
    {
      "id": "coh_registry_crossmatch_03",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 03: International MVA Syndrome Registry",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from International MVA Syndrome Registry.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "International"
      ]
    },
    {
      "id": "coh_registry_crossmatch_04",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 04: TCGA Soft Tissue Sarcoma Cohort",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from TCGA Soft Tissue Sarcoma Cohort.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "TCGA"
      ]
    },
    {
      "id": "coh_registry_crossmatch_05",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 05: ICGC Pediatric Brain Tumor Consortium",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from ICGC Pediatric Brain Tumor Consortium.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "ICGC"
      ]
    },
    {
      "id": "coh_registry_crossmatch_06",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 06: Children's Oncology Group (COG) ARST",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from Children's Oncology Group (COG) ARST.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "Children's"
      ]
    },
    {
      "id": "coh_registry_crossmatch_07",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 07: DECIPHER Rare Disease Database",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from DECIPHER Rare Disease Database.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "DECIPHER"
      ]
    },
    {
      "id": "coh_registry_crossmatch_08",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 08: Genomics England 100,000 Genomes",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from Genomics England 100,000 Genomes.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "Genomics"
      ]
    },
    {
      "id": "coh_registry_crossmatch_09",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 09: DepMap Cancer Dependency Map (PRISM)",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from DepMap Cancer Dependency Map (PRISM).",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "DepMap"
      ]
    },
    {
      "id": "coh_registry_crossmatch_10",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 10: DepMap CRISPR Essentiality Screens",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from DepMap CRISPR Essentiality Screens.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "DepMap"
      ]
    },
    {
      "id": "coh_registry_crossmatch_11",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 11: COSMIC Cell Lines Project",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from COSMIC Cell Lines Project.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "COSMIC"
      ]
    },
    {
      "id": "coh_registry_crossmatch_12",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 12: CIViC Clinical Interpretations",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from CIViC Clinical Interpretations.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "CIViC"
      ]
    },
    {
      "id": "coh_registry_crossmatch_13",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 13: OncoKB Precision Oncology",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from OncoKB Precision Oncology.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "OncoKB"
      ]
    },
    {
      "id": "coh_registry_crossmatch_14",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 14: RDCA-DAP Rare Disease Cures",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from RDCA-DAP Rare Disease Cures.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "RDCA-DAP"
      ]
    },
    {
      "id": "coh_registry_crossmatch_15",
      "category": "Comparative Oncology Cohorts",
      "title": "Cohort Cross-Match 15: AACR Project GENIE Registry",
      "description": "Comparative genomic frequencies, survival statistics, and precision oncology insights from AACR Project GENIE Registry.",
      "row_count": 4,
      "columns_count": 6,
      "tags": [
        "Comparative Oncology",
        "Cohorts",
        "AACR"
      ]
    }
  ]
}