causal-variants: keep the 08:54 lede and benchmark-scope wording

causal-variants.html

@@ -18,7 +18,7 @@
 
 <main class="prose">
 <h1>Zero-shot causal variant prioritisation</h1>
-<p class="lede">545 loci across 14 species, each with an experimentally validated causal SNP. The task: recover that SNP among thousands of neighbouring population variants, using sequence alone.</p>
+<p class="lede">A new and harder zero-shot causal-variant discovery benchmark based on experimentally validated variants, totalling 545 loci across 14 species. Each task ranks one documented causal SNP among population SNPs in its surrounding 100 kbp locus.</p>
 
 <figure class="locus-browser" aria-labelledby="locus-title">
   <div class="locus-heading">
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 <div class="tablewrap"><table id="sweep"></table></div>
 
 <h2 id="limits">Simplifications</h2>
-<p>This benchmark restricts the search to SNPs in a 100 kbp locus. It asks whether the documented causal SNP ranks near the top by absolute LLR. Surrounding unlabelled variants may also be functional or phenotypically relevant, so the benchmark measures recovery of the documented causal SNP rather than identifying every functional variant in the locus.</p>
+<p>This new benchmark also uses some simplifications: the search is limited to a 100 kbp causal region and to a single basic type of mutation, SNPs. Besides, the task relies on the assumption that the documented causal SNP should be ranked among the candidate variants assigned the lowest likelihood by the model, an assumption that could be challenged since the surrounding unlabelled variants may include other functional or phenotypically relevant mutations. This limitation affects the interpretation of the absolute benchmark scores, but not the relative comparison between methods, since all methods are evaluated against the same set of unlabelled variants.</p>
 
 <h2 id="sec-studies">The 545 studies</h2>
 <p>Below are 20 example studies from the benchmark. The full set of 545 studies, candidate variants, and curation audit will be published later.</p>